Baclofen, a GABAB receptor agonist, inhibits human hepatocellular carcinoma cell growth in vitro and in vivo

Life Sciences

Volumn 82, Issue 9-10, 2008, Pages 536-541

  Wang, Tao ^a   Huang, Wei ^b   Chen, Fei ^c  

^a NATIONAL ENGINEERING CENTER FOR BIOCHIP AT SHANGHAI   (China)

^b ZHEJIANG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Baclofen; GABAB receptor; Growth; Hepatocellular carcinoma

Indexed keywords

4 AMINOBUTYRIC ACID; BACLOFEN; CYCLIC AMP; CYCLIN DEPENDENT KINASE INHIBITOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER GROWTH; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION;

ANIMALS; BACLOFEN; CARCINOMA, HEPATOCELLULAR; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIC AMP; CYCLIN-DEPENDENT KINASE INHIBITOR P21; GABA AGONISTS; HUMANS; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; RADIOIMMUNOASSAY; RECEPTORS, GABA-B; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 39149131369     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2007.12.014     Document Type: Article

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