메뉴 건너뛰기




Volumn 20, Issue 6, 2009, Pages 477-482

Prevention of pancreatic cancer by the beta-blocker propranolol

Author keywords

Beta blocker; cAMP signaling; Nicotinic acetylcholine receptor; Pancreatic cancer prevention

Indexed keywords

2 BUTANONE; ALCOHOL; BETA ADRENERGIC RECEPTOR; BUNGAROTOXIN RECEPTOR; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; EPIDERMAL GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NITROSAMINE 4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; PROPRANOLOL; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 67249100746     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/CAD.0b013e32832bd1e3     Document Type: Article
Times cited : (97)

References (36)
  • 1
    • 33646940131 scopus 로고    scopus 로고
    • Current therapies and advances in the treatment of pancreatic cancer
    • DOI 10.1016/j.critrevonc.2006.02.004, PII S1040842806000400
    • Mancuso A, Calabro F, Sternberg CN. Current therapies and advances in the treatment of pancreatic cancer. Crit Rev Oncol Hematol 2006; 58:231-241. (Pubitemid 43796083)
    • (2006) Critical Reviews in Oncology/Hematology , vol.58 , Issue.3 , pp. 231-241
    • Mancuso, A.1    Calabro, F.2    Sternberg, C.N.3
  • 3
    • 0035098423 scopus 로고    scopus 로고
    • Beta-Adrenergic growth regulation of human cancer cell lines derived from pancreatic ductal carcinomas
    • Weddle DL, Tithoff P, Williams M, Schuller HM. Beta-adrenergic growth regulation of human cancer cell lines derived from pancreatic ductal carcinomas. Carcinogenesis 2001; 22:473-479. (Pubitemid 32203828)
    • (2001) Carcinogenesis , vol.22 , Issue.3 , pp. 473-479
    • Weddle, D.L.1    Tithoff, P.2    Williams, M.3    Schuller, H.M.4
  • 4
    • 27144434360 scopus 로고    scopus 로고
    • The tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1- Butanone stimulates proliferation of immortalized human pancreatic duct epithelia through beta-adrenergic transactivation of EGF receptors
    • DOI 10.1007/s00432-005-0002-7
    • Askari MD, Tsao MS, Schuller HM. The tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone stimulates proliferation of immortalized human pancreatic duct epithelia through beta-adrenergic transactivation of EGF receptors. J Cancer Res Clin Oncol 2005; 131:639-648. (Pubitemid 41502206)
    • (2005) Journal of Cancer Research and Clinical Oncology , vol.131 , Issue.10 , pp. 639-648
    • Askari, M.D.F.1    Tsao, M.-S.2    Schuller, H.M.3
  • 5
    • 4544305469 scopus 로고    scopus 로고
    • Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanone promotes functional cooperation of Bcl2 and c-Myc through phosphorylation in regulating cell survival and proliferation
    • DOI 10.1074/jbc.M404056200
    • Jin Z, Gao F, Flagg T, Deng X. Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone promotes functional cooperation of Bcl2 and c-Myc through phosphorylation in regulating cell survival and proliferation. J Biol Chem 2004; 279:40209-40219. (Pubitemid 39258297)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.38 , pp. 40209-40219
    • Jin, Z.1    Gao, F.2    Flagg, T.3    Deng, X.4
  • 6
    • 33747450166 scopus 로고    scopus 로고
    • NNK activates ERK1/2 and CREB/ATF-1 via beta-1-AR and EGFR signaling in human lung adenocarcinoma and small airway epithelial cells
    • DOI 10.1002/ijc.21987
    • Laag E, Majidi M, Cekanova C, Masi T, Takahashi T, Schuller HM. NNK activates ERK1/2 and CREB/ATF-1 via beta-1-AR and EGFR signaling in human lung adenocarcinoma and small airway epithelial cells. Int J Cancer 2006; 119:1547-1552. (Pubitemid 44258759)
    • (2006) International Journal of Cancer , vol.119 , Issue.7 , pp. 1547-1552
    • Laag, E.1    Majidi, M.2    Cekanova, M.3    Masi, T.4    Takahashi, T.5    Schuller, H.M.6
  • 8
    • 0035300538 scopus 로고    scopus 로고
    • Norepinephrine-induced migration of SW 480 colon carcinoma cells is inhibited by beta-blockers
    • Masur K, Niggemann B, Zanker KS, Entschladen F. Norepinephrine-induced migration of SW 480 colon carcinoma cells is inhibited by beta-blockers. Cancer Res 2001; 61:2866-2869. (Pubitemid 32691927)
    • (2001) Cancer Research , vol.61 , Issue.7 , pp. 2866-2869
    • Masur, K.1    Niggemann, B.2    Zanker, K.S.3    Entschladen, F.4
  • 9
    • 33646371479 scopus 로고    scopus 로고
    • The norepinephrine-driven metastasis development of PC-3 human prostate cancer cells in BALB/c nude mice is inhibited by beta-blockers
    • DOI 10.1002/ijc.21723
    • Palm D, Lang K, Niggemann B, Drell TLT, Masur K, Zaenker KS, et al. The norepinephrine-driven metastasis development of PC-3 human prostate cancer cells in BALB/c nude mice is inhibited by beta-blockers. Int J Cancer 2006; 118:2744-2749. (Pubitemid 43673352)
    • (2006) International Journal of Cancer , vol.118 , Issue.11 , pp. 2744-2749
    • Palm, D.1    Lang, K.2    Niggemann, B.3    Drell IV, T.L.4    Masur, K.5    Zaenker, K.S.6    Entschladen, F.7
  • 12
    • 0027240991 scopus 로고
    • Transplacental induction of pancreas tumors in hamsters by ethanol and the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
    • Schuller HM, Jorquera R, Reichert A, Castonguay A. Transplacental induction of pancreas tumors in hamsters by ethanol and the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Cancer Res 1993; 53:2498-2501. (Pubitemid 23168012)
    • (1993) Cancer Research , vol.53 , Issue.11 , pp. 2498-2501
    • Schuller, H.M.1    Jorquera, R.2    Reichert, A.3    Castonguay, A.4
  • 13
    • 0036033780 scopus 로고    scopus 로고
    • The cyclooxygenase inhibitor ibuprofen and the FLAP inhibitor MK886 inhibit pancreatic carcinogenesis induced in hamsters by transplacental exposure to ethanol and the tobacco carcinogen NNK
    • DOI 10.1007/s00432-002-0365-y
    • Schuller HM, Zhang L, Weddle DL, Castonguay A, Walker K, Miller MS. The cyclooxygenase inhibitor ibuprofen and the FLAP inhibitor MK886 inhibit pancreatic carcinogenesis induced in hamsters by transplacental exposure to ethanol and the tobacco carcinogen NNK. J Cancer Res Clin Oncol 2002; 128:525-532. (Pubitemid 35244927)
    • (2002) Journal of Cancer Research and Clinical Oncology , vol.128 , Issue.10 , pp. 525-532
    • Schuller, H.1    Zhang, L.2    Weddle, D.3    Castonguay, A.4    Walker, K.5    Miller, M.6
  • 14
    • 67650927348 scopus 로고    scopus 로고
    • Nicotinic receptor-associated modulation of stimulatory and inhibitory neurotransmitters in NNK-induced adenocarcinoma of the lungs and pancreas
    • in press
    • Al-Wadei HAN, Schuller HM. Nicotinic receptor-associated modulation of stimulatory and inhibitory neurotransmitters in NNK-induced adenocarcinoma of the lungs and pancreas. J Pathol (in press).
    • J Pathol
    • Al-Wadei, H.A.N.1    Schuller, H.M.2
  • 15
    • 33947253249 scopus 로고    scopus 로고
    • Overexpressed Raf-1 and phosphorylated cyclic adenosine 3′-5′-monophosphatate response element-binding protein are early markers for lung adenocarcinoma
    • DOI 10.1002/cncr.22520
    • Cekanova M, Majidy M, Masi T, Al-Wadei HA, Schuller HM. Overexpressed Raf-1 and phosphorylated cyclic adenosine 3′-5′-monophosphatate response element-binding protein are early markers for lung adenocarcinoma. Cancer 2007; 109:1164-1173. (Pubitemid 46435397)
    • (2007) Cancer , vol.109 , Issue.6 , pp. 1164-1173
    • Cekanova, M.1    Majidy, M.2    Masi, T.3    Al-Wadei, H.A.N.4    Schuller, H.M.5
  • 16
    • 31044439244 scopus 로고    scopus 로고
    • Indirect modulation by alpha7 nicotinic acetylcholine receptors of noradrenaline release in rat hippocampal slices: Interaction with glutamate and GABA systems and effect of nicotine withdrawal
    • DOI 10.1124/mol.105.018184
    • Barik J, Wonnacott S. Indirect modulation by alpha7 nicotinic acetylcholine receptors of noradrenaline release in rat hippocampal slices: interaction with glutamate and GABA systems and effect of nicotine withdrawal. Mol Pharmacol 2006; 69:618-628. (Pubitemid 43121959)
    • (2006) Molecular Pharmacology , vol.69 , Issue.2 , pp. 618-628
    • Barik, J.1    Wonnacott, S.2
  • 17
    • 0030623464 scopus 로고    scopus 로고
    • Notice and sympathetic neurotransmission
    • DOI 10.1007/BF00053022
    • Haass M, Kubler W. Nicotine and sympathetic neurotransmission. Cardiovasc Drugs Ther 1997; 19:657-665. (Pubitemid 27129768)
    • (1997) Cardiovascular Drugs and Therapy , vol.10 , Issue.6 , pp. 657-665
    • Haass, M.1    Kubler, W.2
  • 18
    • 34249776345 scopus 로고    scopus 로고
    • Nicotine promotes cell proliferation via alpha7-nicotinic acetylcholine receptor and catecholamine-synthesizing enzymes-mediated pathway in human colon adenocarcinoma HT-29 cells
    • DOI 10.1016/j.taap.2007.04.002, PII S0041008X07001639
    • Wong HP, Yu L, Lam EK, Tai EK, Wu WK, Cho CH. Nicotine promotes cell proliferation via alpha7-nicotinic acetylcholine receptor and catecholamine-synthesizing enzymes-mediated pathway in human colon adenocarcinoma HT-29 cells. Toxicol Appl Pharmacol 2007; 221:261-267. (Pubitemid 46855813)
    • (2007) Toxicology and Applied Pharmacology , vol.221 , Issue.3 , pp. 261-267
    • Wong, H.P.S.1    Yu, L.2    Lam, E.K.Y.3    Tai, E.K.K.4    Wu, W.K.K.5    Cho, C.H.6
  • 19
    • 34248345864 scopus 로고    scopus 로고
    • Chronic pancreatitis, pseudotumors and other tumor-like lesions
    • DOI 10.1038/modpathol.3800690, PII 3800690
    • Klöppel G. Chronic pancreatitis, pseudotumors and other tumor-like lesions. Modern Pathology 2007; 20:S113-S131. (Pubitemid 46733658)
    • (2007) Modern Pathology , vol.20 , Issue.1 SUPPL.
    • Kloppel, G.1
  • 20
    • 34547903586 scopus 로고    scopus 로고
    • Validation of the 6th edition AJCC pancreatic cancer staging system: Report from the National Cancer Database
    • Bilimoria KY, Bentrem DJ, Ko CY, Ritchey J, Stewart AK, Winchester DP, et al. Validation of the 6th edition AJCC pancreatic cancer staging system: report from the National Cancer Database. Cancer 2007; 110:738-744.
    • (2007) Cancer , vol.110 , pp. 738-744
    • Bilimoria, K.Y.1    Bentrem, D.J.2    Ko, C.Y.3    Ritchey, J.4    Stewart, A.K.5    Winchester, D.P.6
  • 21
    • 34248335374 scopus 로고    scopus 로고
    • Pancreatic adenocarcinoma: Update on the surgical pathology of carcinomas of ductal origin and PanINs
    • DOI 10.1038/modpathol.3800685
    • Hruban RH, Fukushima N. Pancreatic adenocarcinoma: update on the surgical pathology of carcinomas of ductal origin and PanlNs. Modern Pathology 2007; 20:S61-S70. (Pubitemid 46733656)
    • (2007) Modern Pathology , vol.20 , Issue.1 SUPPL.
    • Hruban, R.H.1    Fukushima, N.2
  • 22
    • 0033568544 scopus 로고    scopus 로고
    • The tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1- Butanone is a beta-adrenergic agonist and stimulates DNA synthesis in lung adenocarcinoma via beta-adrenergic receptor-mediated release of arachidonic acid
    • Schuller HM, Tithof PK, Williams M, Plummer H 3rd. The tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone is a beta-adrenergic agonist and stimulates DNA synthesis in lung adenocarcinoma via beta-adrenergic receptor-mediated release of arachidonic acid. Cancer Res 1999; 59:4510-4515. (Pubitemid 29428948)
    • (1999) Cancer Research , vol.59 , Issue.18 , pp. 4510-4515
    • Schuller, H.M.1    Tithof, P.K.2    Williams, M.3    Plummer III, H.4
  • 23
    • 64049109101 scopus 로고    scopus 로고
    • Beta-carotene promotes the development of NNK-induced small airway-derived lung adenocarcinoma
    • in press
    • Al-Wadei HAN, Schuller HM. Beta-carotene promotes the development of NNK-induced small airway-derived lung adenocarcinoma. Eur J Cancer. (in press).
    • Eur J Cancer
    • Al-Wadei, H.A.N.1    Schuller, H.M.2
  • 24
    • 0032499397 scopus 로고    scopus 로고
    • Tobacco-specific carcinogenic nitrosamines: Ligands for nicotinic acetylcholine receptors in human lung cancer cells
    • DOI 10.1016/S0006-2952(97)00651-5, PII S0006295297006515
    • Schuller HM, Orloff M. Tobacco-specific carcinogenic nitrosamines. Ligands for nicotinic acetylcholine receptors in human lung cancer cells. Biochem Pharmacol 1998; 55:1377-1384. (Pubitemid 28298517)
    • (1998) Biochemical Pharmacology , vol.55 , Issue.9 , pp. 1377-1384
    • Schuller, H.M.1    Orloff, M.2
  • 25
    • 34249284421 scopus 로고    scopus 로고
    • Nitrosamines as nicotinic receptor ligands
    • DOI 10.1016/j.lfs.2007.03.006, PII S002432050700255X, Proceedings of the 2nd International Symposium on Non-neuronal Acetylcholine
    • Schuller HM. Nitrosamines as nicotinic receptor ligands. Life Sci 2007; 80:2274-2280. (Pubitemid 46818287)
    • (2007) Life Sciences , vol.80 , Issue.24-25 , pp. 2274-2280
    • Schuller, H.M.1
  • 26
    • 33646800564 scopus 로고    scopus 로고
    • Nicotinic receptors mediate tumorigenic action of tobacco-derived nitrosamines on immortalized oral epithelial cells
    • Arredondo J, Chernyavsky AI, Grando SA. Nicotinic receptors mediate tumorigenic action of tobacco-derived nitrosamines on immortalized oral epithelial cells. Cancer Biol Ther 2006; 5:511-517. (Pubitemid 43765286)
    • (2006) Cancer Biology and Therapy , vol.5 , Issue.5 , pp. 511-517
    • Arredondo, J.1    Chernyavsky, A.I.2    Grando, S.A.3
  • 29
    • 51049114513 scopus 로고    scopus 로고
    • Neurotransmission and cancer: Implications for prevention and therapy
    • Schuller HM. Neurotransmission and cancer: implications for prevention and therapy. Anticancer Drugs 2008; 19:655-671.
    • (2008) Anticancer Drugs , vol.19 , pp. 655-671
    • Schuller, H.M.1
  • 30
    • 34548396785 scopus 로고    scopus 로고
    • Statins prevent cholinesterase inhibitor blockade of sympathetic alpha7-nAChR-mediated currents in rat superior cervical ganglion neurons
    • DOI 10.1152/ajpheart.00269.2007
    • Mozayan M, Lee TJ. Statins prevent cholinesterase inhibitor blockade of sympathetic alpha7 nAChR-mediated currents in rat superior cervical ganglion neurons. Am J Physiol Heart Circ Physiol 2007; 293:H1737-H1744. (Pubitemid 47367222)
    • (2007) American Journal of Physiology - Heart and Circulatory Physiology , vol.293 , Issue.3
    • Mozayan, M.1    Lee, T.J.F.2
  • 31
    • 34447562804 scopus 로고    scopus 로고
    • Nicotine promotes colon tumor growth and angiogenesis through beta-adrenergic activation
    • DOI 10.1093/toxsci/kfm060
    • Wong HP, Yu L, Lam EK, Tai EK, Wu WK, Cho CH. Nicotine promotes colon tumor growth and angiogenesis through beta-adrenergic activatriton. Toxicol Sci 2007; 97:279-287. (Pubitemid 47073845)
    • (2007) Toxicological Sciences , vol.97 , Issue.2 , pp. 279-287
    • Wong, H.P.S.1    Yu, L.2    Lam, E.K.Y.3    Tai, E.K.K.4    Wu, W.K.K.5    Cho, C.-H.6
  • 33
    • 0030960068 scopus 로고    scopus 로고
    • Interaction between adrenaline and epidermal growth factor in the control of liver glycogenolysis in mouse
    • DOI 10.1210/en.138.6.2601
    • Grau M, Soley M, Ramirez I. Interaction between adrenaline and epidermal growth factor in the control of liver glycogenosis in mouse. Endocrinology 1997; 138:2601-2609. (Pubitemid 27215268)
    • (1997) Endocrinology , vol.138 , Issue.6 , pp. 2601-2609
    • Grau, M.1    Soley, M.2    Ramirez, I.3
  • 34
    • 60749101452 scopus 로고    scopus 로고
    • Is cancer triggered by altered signalling of nicotinic acetylcholine receptors?
    • Schuller HM. Is cancer triggered by altered signalling of nicotinic acetylcholine receptors? Nat Rev Cancer 2009; 9:195-205.
    • (2009) Nat Rev Cancer , vol.9 , pp. 195-205
    • Schuller, H.M.1
  • 36
    • 34548282539 scopus 로고    scopus 로고
    • Isoform-specific enhancement of adenylyl cyclase activity by n-alkanols
    • DOI 10.1111/j.1530-0277.2007.00455.x
    • Kou J, Yoshimura M. Isoform-specific enhancement of adenylyl cyclase activity by n-alkanols. Alcohol Clin Exp Res 2007; 31:1467-1472. (Pubitemid 47319663)
    • (2007) Alcoholism: Clinical and Experimental Research , vol.31 , Issue.9 , pp. 1467-1472
    • Kou, J.1    Yoshimura, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.