메뉴 건너뛰기




Volumn 6, Issue 2, 2011, Pages 82-92

Mesenchymal stem cells neuronal differentiation ability: A real perspective for nervous system repair?

Author keywords

Mesenchymal stem cells; Nervous system repair; Neuronal differentiation

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BUTYLATED HYDROXYANISOLE; CYTOKINE; DIMETHYL SULFOXIDE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MERCAPTOETHANOL; NEUROGENIN 1; NEUROTRANSMITTER; NEUROTROPHIC FACTOR; NOTCH RECEPTOR; RETINOIC ACID; TRANSCRIPTION FACTOR;

EID: 79955684801     PISSN: 1574888X     EISSN: None     Source Type: Journal    
DOI: 10.2174/157488811795495486     Document Type: Article
Times cited : (101)

References (110)
  • 1
    • 0030889354 scopus 로고    scopus 로고
    • Marrow stromal cells as stem cells for non-hematopoietic tissues
    • Prockop DJ. Marrow stromal cells as stem cells for non-hematopoietic tissues. Science 1997; 276: 71-74.
    • (1997) Science , vol.276 , pp. 71-74
    • Prockop, D.J.1
  • 2
    • 0033515827 scopus 로고    scopus 로고
    • Multilineage potential of adult human mesenchymal stem cells
    • Pittenger MF, MacKay AM, Beck SC, et al. Multilineage potentialof adult human mesenchymal stem cells. Science 1999; 284: 147-43.
    • (1999) Science , vol.284 , pp. 147-143
    • Pittenger, M.F.1    Mackay, A.M.2    Beck, S.C.3
  • 3
    • 33747713246 scopus 로고    scopus 로고
    • Minimal criteria fordefining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statemen
    • Dominici M, Le Blanc K, Mueller I, et al. Minimal criteria fordefining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 2006;4: 315-317.
    • (2006) Cytotherapy , vol.4 , pp. 315-317
    • Dominici, M.1    le Blanc, K.2    Mueller, I.3
  • 4
    • 33645462716 scopus 로고    scopus 로고
    • Neural transdifferentiation of mes-enchymal stem cells--a critical revie
    • Krabbe C, Zimmer J, Meyer M. Neural transdifferentiation of mes-enchymal stem cells--a critical review. APMIS 2005; 113: 831-844.
    • (2005) APMIS , vol.113 , pp. 831-844
    • Krabbe, C.1    Zimmer, J.2    Meye, M.3
  • 5
    • 33750742274 scopus 로고    scopus 로고
    • Mesenchymal stem cell: Characteristics and clinical applications
    • Bobis S, Jarocha D, Majka M. Mesenchymal stem cell: characteristics and clinical applications. Folia Histochem Cytobiol 2006; 44:215-230.
    • (2006) Folia Histochem Cytobiol , vol.44 , pp. 215-230
    • Bobis, S.1    Jarocha, D.2    Majka, M.3
  • 6
    • 79551475969 scopus 로고    scopus 로고
    • Opening the mesenchymal stem celltool box
    • Zeidán-Chuliá F, Noda M. Opening the mesenchymal stem celltool box. Eur J Dent 2009; 3: 240-249.
    • (2009) Eur J Dent , vol.3 , pp. 240-249
    • Zeidán-Chuliá, F.1    Noda, M.2
  • 7
    • 0037442264 scopus 로고    scopus 로고
    • Sup-pression of allogeneic T-cell proliferation by human marrow stro-mal cells: Implications in transplantatio
    • Tse WT, Pendleton JD, Beyer WM, Egalka MC, Guinan EC. Sup-pression of allogeneic T-cell proliferation by human marrow stro-mal cells: implications in transplantation. Transplantation 2003; 75:389-397.
    • (2003) Transplantation , vol.75 , pp. 389-397
    • Tse, W.T.1    Pendleton, J.D.2    Beyer, W.M.3    Egalka, M.C.4    Guinan, E.C.5
  • 8
    • 50249158511 scopus 로고    scopus 로고
    • Mesenchymal stem cells in healthand diseas
    • Uccelli A, Moretta L, Pistoia V. Mesenchymal stem cells in healthand disease. Nat Rev Immunol 2008; 8: 726-36.
    • (2008) Nat Rev Immunol , vol.8 , pp. 726-736
    • Uccelli, A.1    Moretta, L.2    Pistoia, V.3
  • 9
    • 0034663515 scopus 로고    scopus 로고
    • Adult rat andhuman bone marrow stromal cells differentiate into neuron
    • Woodbury D, Schwarz EJ, Prockop DJ, Black IB. Adult rat andhuman bone marrow stromal cells differentiate into neurons. J Neu-rosci Res 2000; 61: 364-70.
    • (2000) J Neurosci Res , vol.61 , pp. 364-370
    • Woodbury, D.1    Schwarz, E.J.2    Prockop, D.J.3    Black, I.B.4
  • 10
    • 0034537437 scopus 로고    scopus 로고
    • Adult bonemarrow stromal cells differentiate into neural cells in vitro
    • Sanchez-Ramos J, Song S, Cardozo-Pelaez F, et al. Adult bonemarrow stromal cells differentiate into neural cells in vitro. ExpNeurol 2000; 164: 247-56.
    • (2000) ExpNeurol , vol.164 , pp. 247-256
    • Sanchez-Ramos, J.1    Song, S.2    Cardozo-Pelaez, F.3
  • 11
    • 0034809239 scopus 로고    scopus 로고
    • In vitro differentiationof human marrow stromal cells into early progenitors of neuralcells by conditions that increase intracellular cyclic AMP
    • [Deng W, Obrocka M, Fischer I, Prockop DJ. In vitro differentiationof human marrow stromal cells into early progenitors of neuralcells by conditions that increase intracellular cyclic AMP. BiochemBiophys Res Commun 2001; 282: 148-52.
    • (2001) BiochemBiophys Res Commun , vol.282 , pp. 148-152
    • Deng, W.1    Obrocka, M.2    Fischer, I.3    Prockop, D.J.4
  • 12
    • 0142027130 scopus 로고    scopus 로고
    • Cell death andlong-term maintenance of neuron-like state after differentiation ofrat bone marrow stromal cells: A comparison of protocol
    • Rismanchi N, Floyd CL, Berman RF, Lyeth BG. Cell death andlong-term maintenance of neuron-like state after differentiation ofrat bone marrow stromal cells: a comparison of protocols. BrainRes 2003; 991: 46-55.
    • (2003) BrainRes , vol.991 , pp. 46-55
    • Rismanchi, N.1    Floyd, C.L.2    Berman, R.F.3    Lyeth, B.G.4
  • 13
    • 3042798843 scopus 로고    scopus 로고
    • Induction of bone marrow stromalcells to neurons: Differentiation, transdifferentiation, or artifact
    • Lu P, Blesch A, Tuszynski MH. Induction of bone marrow stromalcells to neurons: differentiation, transdifferentiation, or artifact? JNeurosci Res 2004; 77: 174-91.
    • (2004) J Neurosci Res , vol.77 , pp. 174-191
    • Lu, P.1    Blesch, A.2    Tuszynski, M.H.3
  • 14
    • 3042801100 scopus 로고    scopus 로고
    • Fischer I.Reevaluation of in vitro differentiation protocols for bone marrowstromal cells: Disruption of actin cytoskeleton induces rapid morphological changes and mimics neuronal phenotype
    • Neuhuber B, Gallo G, Howard L, Kostura L, Mackay A, Fischer I.Reevaluation of in vitro differentiation protocols for bone marrowstromal cells: disruption of actin cytoskeleton induces rapid morphological changes and mimics neuronal phenotype. J NeurosciRes 2004; 77: 192-204.
    • (2004) J Neurosci Res , vol.77 , pp. 192-204
    • Neuhuber, B.1    Gallo, G.2    Howard, L.3    Kostura, L.4    Mackay, A.5
  • 15
    • 26244441779 scopus 로고    scopus 로고
    • Neurogenicpotential of human mesenchymal stem cells revisited: Analysis byimmunostaining, time-lapse video and microarra
    • Bertani N, Malatesta P, Volpi G, Sonego P, Perris R. Neurogenicpotential of human mesenchymal stem cells revisited: analysis byimmunostaining, time-lapse video and microarray. J Cell Sci 2005;118: 3925-36.
    • (2005) J Cell Sci , vol.118 , pp. 3925-3936
    • Bertani, N.1    Malatesta, P.2    Volpi, G.3    Sonego, P.4    Perris, R.5
  • 16
    • 33749067408 scopus 로고    scopus 로고
    • Analysis of neuron-like differentiation of human bone marrow mesenchymal stem cells
    • Choi CB, Cho YK, Prakash KV, et al. Analysis of neuron-likedifferentiation of human bone marrow mesenchymal stem cells.Biochem Biophys Res Commun 2006; 350: 138-46.
    • (2006) Biochem Biophys Res Commu , vol.350 , pp. 138-146
    • Choi, C.B.1    Cho, Y.K.2    Prakash, K.V.3
  • 17
    • 33749342295 scopus 로고    scopus 로고
    • Immunochemical, ultrastructural and electrophysiological investigations of bone-derived stem cells in the course of neuronal differentiation
    • Wenisch S, Trinkaus K, Hild A, et al. Immunochemical, ultrastructural and electrophysiological investigations of bone-derived stem cells in the course of neuronal differentiation. Bone 2006; 38: 911-21.
    • (2006) Bone , vol.38 , pp. 911-921
    • Wenisch, S.1    Trinkaus, K.2    Hild, A.3
  • 18
    • 65349106547 scopus 로고    scopus 로고
    • Chemically-induced RAT mesenchymal stem cells adopt molecular properties of neuronal-like cells but do not have basic neuronal functional properties
    • Barnabé GF, Schwindt TT, Calcagnotto ME, et al. Chemically-induced RAT mesenchymal stem cells adopt molecular properties of neuronal-like cells but do not have basic neuronal functional properties. PLoS One 2009; 4: e5222.
    • (2009) PLoS One , vol.4
    • Barnabé, G.F.1    Schwindt, T.T.2    Calcagnotto, M.E.3
  • 19
    • 33749985102 scopus 로고    scopus 로고
    • Neural differentiationof human mesenchymal stem cells: Evidence for expression of neural markers and eag K+ channel types
    • Mareschi K, Novara M, Rustichelli D, et al. Neural differentiationof human mesenchymal stem cells: Evidence for expression of neu-ral markers and eag K+ channel types. Exp Hematol 2006; 34:1563-1572.
    • (2006) Exp Hematol , vol.34 , pp. 1563-1572
    • Mareschi, K.1    Novara, M.2    Rustichelli, D.3
  • 20
    • 65349131822 scopus 로고    scopus 로고
    • Elevation of cAMP in mesenchymal stem cells transiently upregulates neural markers rather than inducing neural differentiation
    • Rooney GE, Howard L, O'Brien T, Windebank AJ, Barry FP. Elevation of cAMP in mesenchymal stem cells transiently upregulates neural markers rather than inducing neural differentiation. Stem Cells Dev 2009; 18: 387-398.
    • (2009) Stem Cells Dev , vol.18 , pp. 387-983
    • Rooney, G.E.1    Howard, L.2    O'Brien, T.3    Windebank, A.J.4    Barry, F.P.5
  • 21
    • 21744460838 scopus 로고    scopus 로고
    • Molecular pathways involved in neural in vitro differentiation of marrow stromal stemcells
    • Jori FP, Napolitano MA, Melone MA, et al. Molecular pathwaysinvolved in neural in vitro differentiation of marrow stromal stemcells. J Cell Biochem 2005; 94: 645-55.
    • (2005) J Cell Biochem , vol.94 , pp. 645-655
    • Jori, F.P.1    Napolitano, M.A.2    Melone, M.A.3
  • 22
    • 42949171536 scopus 로고    scopus 로고
    • Gene expression pattern of functional neuronal cells derived from human bone marrow mesenchymal stromal cells
    • Tondreau T, Dejeneffe M, Meuleman N, et al. Gene expression pattern of functional neuronal cells derived from human bone mar-row mesenchymal stromal cells. BMC Genomics 2008; 9: 166.
    • (2008) BMC Genomics , vol.9 , pp. 166
    • Tondreau, T.1    Dejeneffe, M.2    Meuleman, N.3
  • 23
    • 0037007985 scopus 로고    scopus 로고
    • Differentiation of adult bonemarrow stem cells into neuroprogenitor cells in vitro
    • Kim BJ, Seo JH, Bubien JK, Oh YS. Differentiation of adult bonemarrow stem cells into neuroprogenitor cells in vitro. Neuroreport 2002; 13: 1185-8.
    • (2002) Neuroreport , vol.13 , pp. 1185-1188
    • Kim, B.J.1    Seo, J.H.2    Bubien, J.K.3    Oh, Y.S.4
  • 24
    • 0344825241 scopus 로고    scopus 로고
    • Improving the expansion and neuronal differentiation of mesenchymal stem cells through culture surface modification
    • Qian L, Saltzman WM. Improving the expansion and neuronal differentiation of mesenchymal stem cells through culture surface modification. Biomaterials 2004; 25: 1331-7.
    • (2004) Biomaterials , vol.25 , pp. 1331-1337
    • Qian, L.1    Saltzman, W.M.2
  • 25
    • 0345257757 scopus 로고    scopus 로고
    • Induction of neuronal markers in bone marrow cells: Differential effects of growth factors and patterns of intracellular expression
    • Jin K, Mao XO, Batteur S, Sun Y, Greenberg DA. Induction ofneuronal markers in bone marrow cells: differential effects ofgrowth factors and patterns of intracellular expression. Exp Neurol 2003; 184: 78-89.
    • (2003) Exp Neurol , vol.184 , pp. 78-89
    • Jin, K.1    Mao, X.O.2    Batteur, S.3    Sun, Y.4    Greenberg, D.A.5
  • 27
    • 36249021493 scopus 로고    scopus 로고
    • Concise review: Mesenchymal stem/multipotent stromal cells: The state of transdifferentiation and modes of tissue repair-current views
    • Phinney DG, Prockop DJ. Concise review: mesenchymalstem/multipotent stromal cells: the state of transdifferentiation andmodes of tissue repair-current views. Stem Cells 2007; 25: 2896-902.
    • (2007) Stem Cells , vol.25 , pp. 2896-2902
    • Phinney, D.G.1    Prockop, D.J.2
  • 28
    • 15544363087 scopus 로고    scopus 로고
    • Neurons derived from human mesenchymal stem cells show synaptic transmission and can be induced to produce the neurotransmitter substance P by interleukin-1alpha
    • Cho KJ, Trzaska KA, Greco SJ, et al. Neurons derived from human mesenchymal stem cells show synaptic transmission and can be induced to produce the neurotransmitter substance P by interleukin-1alpha. Stem Cells 2005; 23: 383-391.
    • (2005) Stem Cells , vol.23 , pp. 383-391
    • Cho, K.J.1    Trzaska, K.A.2    Greco, S.J.3
  • 29
    • 36248984369 scopus 로고    scopus 로고
    • An interdisciplinary approach and characterization of neuronal cells transdifferentiated from human mesenchymal stem cell
    • Greco SJ, Zhou C, Ye JH, Rameshwar P. An interdisciplinaryapproach and characterization of neuronal cells transdifferentiatedfrom human mesenchymal stem cells. Stem Cells Dev 2007; 16:811-826.
    • (2007) Stem Cells Dev , vol.16 , pp. 811-826
    • Greco, S.J.1    Zhou, C.2    Ye, J.H.3    Rameshwar, P.4
  • 30
    • 67650472646 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor facilitates maturation of mesenchymal stem cell-derived do-pamine progenitors to functional neuron
    • Trzaska KA, King CC, Li KY, et al. Brain-derived neurotrophicfactor facilitates maturation of mesenchymal stem cell-derived do-pamine progenitors to functional neurons. J Neurochem 2009; 110:1058-1069.
    • (2009) J Neurochem , vol.110 , pp. 1058-1069
    • Trzaska, K.A.1    King, C.C.2    Li, K.Y.3
  • 31
    • 8644265331 scopus 로고    scopus 로고
    • Modification of the brain-derived neurotrophic factor gene: A portal to transform mesenchymal stemcells into advantageous engineering cells for neuroregeneration and neuroprotectio
    • Zhao LX, Zhang J, Cao F, et al. Modification of the brain-derived neurotrophic factor gene: a portal to transform mesenchymal stemcells into advantageous engineering cells for neuroregeneration and neuroprotection. Exp Neurol 2004; 190: 396-406.
    • (2004) Exp Neuro , vol.190 , pp. 396-406
    • Zhao, L.X.1    Zhang, J.2    Cao, F.3
  • 32
    • 3042769428 scopus 로고    scopus 로고
    • Specific induction of neuronal cells from bone marrow stromal cells and application forautologous transplantation
    • Dezawa M, Kanno H, Hoshino M, et al. Specific induction of neuronal cells from bone marrow stromal cells and application forautologous transplantation. J Clin Invest 2004; 113: 1701-1710.
    • (2004) J Clin Invest , vol.113 , pp. 1701-1710
    • Dezawa, M.1    Kanno, H.2    Hoshino, M.3
  • 33
    • 0036304110 scopus 로고    scopus 로고
    • The role of notch in promoting glial and neural stem cell fates
    • Gaiano N, Fishell G. The role of notch in promoting glial and neu-ral stem cell fates. Annu Rev Neurosci 2002; 25: 471-90.
    • (2002) Annu Rev Neurosci , vol.25 , pp. 471-490
    • Gaiano, N.1    Fishell, G.2
  • 34
    • 68249088090 scopus 로고    scopus 로고
    • Committed neural progenitorcells derived from genetically modified bone marrow stromal cells ameliorate deficits in a rat model of stroke
    • Hayase M, Kitada M, Wakao S, et al. Committed neural progenitorcells derived from genetically modified bone marrow stromal cells ameliorate deficits in a rat model of stroke. J Cereb Blood Flow Metab 2009; 29: 1409-1420.
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 1409-1420
    • Hayase, M.1    Kitada, M.2    Wakao, S.3
  • 35
    • 55049110117 scopus 로고    scopus 로고
    • Neural induction with neuro-genin1 increases the therapeutic effects of mesenchymal stem cells in the ischemic brain
    • Kim SS, Yoo SW, Park TS, et al. Neural induction with neuro-genin1 increases the therapeutic effects of mesenchymal stem cells in the ischemic brain. Stem Cells 2008; 26: 2217-2228.
    • (2008) Stem Cells , vol.26 , pp. 2217-2228
    • Kim, S.S.1    Yoo, S.W.2    Park, T.S.3
  • 36
    • 19344378337 scopus 로고    scopus 로고
    • REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis
    • Ballas N, Grunseich C, Lu DD, Speh JC, Mandel G. REST and itscorepressors mediate plasticity of neuronal gene chromatin through out neurogenesis. Cell 2005; 121: 645-57.
    • (2005) Cell , vol.121 , pp. 645-657
    • Ballas, N.1    Grunseich, C.2    Lu, D.D.3    Speh, J.C.4    Mandel, G.5
  • 37
    • 52049101771 scopus 로고    scopus 로고
    • Loss of RE-1 silencing factor in mesenchymal stem cell-derived dopamine progenitors induces functional maturity
    • Trzaska KA, Reddy BY, Munoz JL, Li KY, Ye JH, Rameshwar P.Loss of RE-1 silencing factor in mesenchymal stem cell-deriveddopamine progenitors induces functional maturity. Mol Cell Neu-rosci 2008; 39: 285-290.
    • (2008) Mol Cell Neurosci , vol.39 , pp. 285-290
    • Trzaska, K.A.1    Reddy, B.Y.2    Munoz, J.L.3    Li, K.Y.4    Ye, J.H.5    Rameshwar, P.6
  • 38
    • 44949173148 scopus 로고    scopus 로고
    • NRSF silencing induces neuronal differentiation of human mesenchymal stem cells
    • Yang Y, Li Y, Lv Y, et al. NRSF silencing induces neuronal differ-entiation of human mesenchymal stem cells. Exp Cell Res 2008;314: 2257-65.
    • (2008) Exp Cell Res , vol.314 , pp. 2257-2265
    • Yang, Y.1    Li, Y.2    Lv, Y.3
  • 39
    • 3142521479 scopus 로고    scopus 로고
    • Stem cell therapy for human neurodegenerative disorders-how to make it work
    • Lindvall O, Kokaia Z, Martinez-Serrano A. Stem cell therapy forhuman neurodegenerative disorders-how to make it work. Nat Med 2004; 10: S42-50.
    • (2004) Nat Med , vol.10
    • Lindvall, O.1    Kokaia, Z.2    Martinez-Serrano, A.3
  • 40
    • 0026535505 scopus 로고
    • Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
    • Reynolds BA, Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 1992; 255: 1707-1710.
    • (1992) Science , vol.255 , pp. 1707-1710
    • Reynolds, B.A.1    Weiss, S.2
  • 41
    • 0027538182 scopus 로고
    • Proliferation, differentiation, and long-term culture of primary hippocampal neurons
    • Ray J, Peterson DA, Schinstine M, Gage FH. Proliferation, differ-entiation, and long-term culture of primary hippocampal neurons. Proc Natl Acad Sci USA 1993; 90: 3602-3606.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3602-3606
    • Ray, J.1    Peterson, D.A.2    Schinstine, M.3    Gage, F.H.4
  • 42
    • 24944484633 scopus 로고    scopus 로고
    • Niche-independent symmetrical self-renewal of a mammalian tissue stem cell
    • Conti L, Pollard SM, Gorba T, et al. Niche-independent symmetri-cal self-renewal of a mammalian tissue stem cell. PLoS Biol 2005;3: e283.
    • (2005) PLoS Biol , vol.3
    • Conti, L.1    Pollard, S.M.2    Gorba, T.3
  • 43
    • 0038015593 scopus 로고    scopus 로고
    • The stem-cell menagerie
    • Pevny L, Rao MS. The stem-cell menagerie. Trends Neurosci 2003; 26: 351-9.
    • (2003) Trends Neurosci , vol.26 , pp. 351-359
    • Pevny, L.1    Rao, M.S.2
  • 44
    • 0036938259 scopus 로고    scopus 로고
    • Generation of neural progenitor cells from whole adult bone marrow
    • Kabos P, Ehtesham M, Kabosova A, Black KL, Yu JS. Generationof neural progenitor cells from whole adult bone marrow. Exp Neu-rol 2002; 178: 288-93.
    • (2002) Exp Neurol , vol.178 , pp. 288-293
    • Kabos, P.1    Ehtesham, M.2    Kabosova, A.3    Black, K.L.4    Yu, J.S.5
  • 45
    • 33751197034 scopus 로고    scopus 로고
    • Neural differentiation potential of peripheral blood- and bone-marrow-derived precursor cells
    • Kim S, Honmou O, Kato K, et al. Neural differentiation potentialof peripheral blood- and bone-marrow-derived precursor cells. Brain Res 2006; 1123: 27-33.
    • (2006) Brain Res , vol.1123 , pp. 27-33
    • Kim, S.1    Honmou, O.2    Kato, K.3
  • 46
    • 4444363727 scopus 로고    scopus 로고
    • Neurospheres induced from bone marrow stromal cells are multipotent for differentiation intoneuron, astrocyte, and oligodendrocyte phenotypes
    • Suzuki H, Taguchi T, Tanaka H, et al. Neurospheres induced frombone marrow stromal cells are multipotent for differentiation intoneuron, astrocyte, and oligodendrocyte phenotypes. Biochem Bio-phys Res Commun 2004; 322: 918 22.
    • (2004) Biochem Bio-phys Res Commun , vol.322 , Issue.918 , pp. 22
    • Suzuki, H.1    Taguchi, T.2    Tanaka, H.3
  • 47
    • 57449096327 scopus 로고    scopus 로고
    • Derivation of neural stem cells from mesenchymal stemcells: Evidence for abipotential stem cell population
    • Fu L, Zhu L, Huang Y, Lee TD, Forman SJ, Shih CC. Derivation of neural stem cells from mesenchymal stemcells: evidence for abipotential stem cell population. Stem Cells Dev 2008; 17: 1109-21.
    • (2008) Stem Cells Dev , vol.17 , pp. 1109-1121
    • Fu, L.1    Zhu, L.2    Huang, Y.3    Lee, T.D.4    Forman, S.J.5    Shih, C.C.6
  • 48
    • 5444246148 scopus 로고    scopus 로고
    • Efficient generation of neuralstem cell-like cells from adult human bone marrow stromal cells
    • Hermann A, Gastl R, Liebau S, et al. Efficient generation of neuralstem cell-like cells from adult human bone marrow stromal cells. J Cell Sci 2004; 117: 4411-4422.
    • (2004) J Cell Sci , vol.117 , pp. 4411-4422
    • Hermann, A.1    Gastl, R.2    Liebau, S.3
  • 49
    • 33744914853 scopus 로고    scopus 로고
    • Comparative analysis of neuroectodermal differentiation capacity of human bone marrowstromal cells using various conversion protocol
    • Hermann A, Liebau S, Gastl R, et al. Comparative analysis ofneuroectodermal differentiation capacity of human bone marrowstromal cells using various conversion protocols. J Neurosci Res 2006; 83: 1502-1514.
    • (2006) J Neurosci Res , vol.83 , pp. 1502-1514
    • Hermann, A.1    Liebau, S.2    Gastl, R.3
  • 50
    • 0042887242 scopus 로고    scopus 로고
    • Regulation of neural markers nestin and GFAP expression by cultivated bone marrow stromal cells
    • Wislet-Gendebien S, Leprince P, Moonen G, Rogister B. Regulation of neural markers nestin and GFAP expression by cultivated bone marrow stromal cells. J Cell Sci 2003; 116: 3295-3302.
    • (2003) J Cell Sci , vol.116 , pp. 3295-3302
    • Wislet-Gendebien, S.1    Leprince, P.2    Moonen, G.3    Rogister, B.4
  • 51
    • 33644971648 scopus 로고    scopus 로고
    • Cells enriched in markers of neural tissue-committed stem cells reside in the bone marrow andare mobilized into the peripheral blood following stroke
    • Kucia M, Zhang YP, Reca R, et al. Cells enriched in markers of neural tissue-committed stem cells reside in the bone marrow andare mobilized into the peripheral blood following stroke. Leukemia 2006; 20: 18-28.
    • (2006) Leukemia , vol.20 , pp. 18-28
    • Kucia, M.1    Zhang, Y.P.2    Reca, R.3
  • 52
    • 61949408338 scopus 로고    scopus 로고
    • Mesenchymal stem cells express ingneural antigens instruct a neurogenic cell fate on neural stem cells
    • Croft AP, Przyborski SA. Mesenchymal stem cells express ingneural antigens instruct a neurogenic cell fate on neural stem cells. Exp Neurol 2009; 216: 329-341.
    • (2009) Exp Neurol , vol.216 , pp. 329-341
    • Croft, A.P.1    Przyborski, S.A.2
  • 53
    • 43049112438 scopus 로고    scopus 로고
    • Functional analysis of neuron-likecells differentiated from neural stem cells derived from bone marrow stroma cells in vitro
    • Xu R, Jiang X, Guo Z, et al. Functional analysis of neuron-likecells differentiated from neural stem cells derived from bone mar-row stroma cells in vitro. Cell Mol Neurobiol 2008; 28: 545-558.
    • (2008) Cell Mol Neurobiol , vol.28 , pp. 545-558
    • Xu, R.1    Jiang, X.2    Guo, Z.3
  • 54
    • 33846013213 scopus 로고    scopus 로고
    • Induction of neural-likedifferentiation in human mesenchymal stem cells derived frombone marrow, fat, spleen and thymus
    • Krampera M, Marconi S, Pasini A, et al. Induction of neural-likedifferentiation in human mesenchymal stem cells derived frombone marrow, fat, spleen and thymus. Bone 2007; 40: 382-390.
    • (2007) Bone , vol.40 , pp. 382-390
    • Krampera, M.1    Marconi, S.2    Pasini, A.3
  • 55
    • 18144382616 scopus 로고    scopus 로고
    • Neuroglial differentiation of human bone marrow stem cells in vitro
    • Bossolasco P, Cova L, Calzarossa C, et al. Neuro-glial differentia-tion of human bone marrow stem cells in vitro. Exp Neurol 2005;193: 312-325.
    • (2005) Exp Neurol , vol.193 , pp. 312-325
    • Bossolasco, P.1    Cova, L.2    Calzarossa, C.3
  • 56
    • 15544376664 scopus 로고    scopus 로고
    • Plasticity of cultured mesenchymal stem cells: Switch from nestin-positive to excitable neuron-like phenotype
    • Wislet-Gendebien S, Hans G, Leprince P, Rigo JM, Moonen G, Rogister B. Plasticity of cultured mesenchymal stem cells: switchfrom nestin-positive to excitable neuron-like phenotype. Stem Cells 2005; 23: 392-402.
    • (2005) Stem Cells , vol.23 , pp. 392-402
    • Wislet-Gendebien, S.1    Hans, G.2    Leprince, P.3    Rigo, J.M.4    Moonen, G.5    Rogister, B.6
  • 57
    • 33745443596 scopus 로고    scopus 로고
    • Autoreactive T cells induce in vitro BM mesenchymalstem cell transdifferentiation to neural stem cells
    • Moviglia GA, Varela G, Gaeta CA, Brizuela JA, Bastos F, Saslavsky J. Autoreactive T cells induce in vitro BM mesenchymalstem cell transdifferentiation to neural stem cells. Cytotherapy 2006; 8: 196-201.
    • (2006) Cytotherapy , vol.8 , pp. 196-201
    • Moviglia, G.A.1    Varela, G.2    Gaeta, C.A.3    Brizuela, J.A.4    Bastos, F.5    Saslavsky, J.6
  • 58
    • 62649113015 scopus 로고    scopus 로고
    • Neural differentiation potential of human bone marrow-derived mesenchymal stromal cells: Misleading marker gene expression
    • Montzka K, Lassonczyk N, Tschöke B, et al. Neural differentiationpotential of human bone marrow-derived mesenchymal stromalcells: misleading marker gene expression. BMC Neurosci 2009; 10:16.
    • (2009) BMC Neurosci , vol.10 , pp. 16
    • Montzka, K.1    Lassonczyk, N.2    Tschöke, B.3
  • 59
    • 1942455363 scopus 로고    scopus 로고
    • Regulatory genes controlling cellfate choice in embryonic and adult neural stem cells
    • Gangemi RM, Perera M, Corte G. Regulatory genes controlling cellfate choice in embryonic and adult neural stem cells. J Neurochem 2004; 89: 286-306.
    • (2004) J Neurochem , vol.89 , pp. 286-306
    • Gangemi, R.M.1    Perera, M.2    Corte, G.3
  • 60
    • 34547838109 scopus 로고    scopus 로고
    • Cell fate specification in the mammalian telencepha-lon
    • Guillemot F. Cell fate specification in the mammalian telencepha-lon. Prog Neurobiol 2007; 83: 37-52.
    • (2007) Prog Neurobiol , vol.83 , pp. 37-52
    • Guillemot, F.1
  • 61
    • 58349119327 scopus 로고    scopus 로고
    • Epigenetic background of neuronal fate determination
    • Wen S, Li H, Liu J. Epigenetic background of neuronal fate deter-mination. Prog Neurobiol 2009; 87: 98-117.
    • (2009) Prog Neurobiol , vol.87 , pp. 98-117
    • Wen, S.1    Li, H.2    Liu, J.3
  • 63
    • 4444342868 scopus 로고    scopus 로고
    • Expression profiling and functional analysis of wnt signaling mechanisms inmesenchymal stem cells
    • Etheridge SL, Spencer GJ, Heath DJ, Genever PG. Expressionprofiling and functional analysis of wnt signaling mechanisms inmesenchymal stem cells. Stem Cells 2004; 22: 849-60.
    • (2004) Stem Cells , vol.22 , pp. 849-860
    • Etheridge, S.L.1    Spencer, G.J.2    Heath, D.J.3    Genever, P.G.4
  • 64
    • 59649100796 scopus 로고    scopus 로고
    • Wnt signaling controls the fate of mesenchymal stem cells
    • Ling L, Nurcombe V, Cool SM. Wnt signaling controls the fate of mesenchymal stem cells. Gene 2009; 433: 1-7.
    • (2009) Gene , vol.433 , pp. 1-7
    • Ling, L.1    Nurcombe, V.2    Cool, S.M.3
  • 65
    • 34548092682 scopus 로고    scopus 로고
    • Effects of Notch-1 signalling pathway on differentiation of marrow mesenchymal stem cells into neurons in vitro
    • Yanjie J, Jiping S, Yan Z, Xiaofeng Z, Boai Z, Yajun L. Effects ofNotch-1 signalling pathway on differentiation of marrow mesen-chymal stem cells into neurons in vitro. Neuroreport 2007; 18:1443-7.
    • (2007) Neuroreport , vol.18 , pp. 1443-1447
    • Yanjie, J.1    Jiping, S.2    Yan, Z.3    Xiaofeng, Z.4    Boai, Z.5    Yajun, L.6
  • 66
    • 0036155343 scopus 로고    scopus 로고
    • Suppression of differentiation and proliferation of early chondrogenic cells by Notch
    • Tezuka K, Yasuda M, Watanabe N, et al. Suppression of differen-tiation and proliferation of early chondrogenic cells by Notch. JBone Miner Res 2002; 17: 231-9.
    • (2002) J Bone Miner Res , vol.17 , pp. 231-239
    • Tezuka, K.1    Yasuda, M.2    Watanabe, N.3
  • 67
    • 42049112734 scopus 로고    scopus 로고
    • MAPK as mediator of cell fate determination: An approach to neurodegenerative diseases
    • Miloso M, Scuteri A, Foudah D, Tredici G. MAPK as mediator of cell fate determination: an approach to neurodegenerative diseases. Curr Med Chem 2008; 15: 538-548.
    • (2008) Curr Med Chem , vol.15 , pp. 538-548
    • Miloso, M.1    Scuteri, A.2    Foudah, D.3    Tredici, G.4
  • 68
    • 69549126263 scopus 로고    scopus 로고
    • Amyloid beta-derived neuro-plasticity in bone marrow-derived mesenchymal stem cells is mediated by NPY and 5-HT2B receptors via ERK1/2 signalling path-ways
    • Jin HK, Bae JS, Furuya S, Carter JE. Amyloid beta-derived neuro-plasticity in bone marrow-derived mesenchymal stem cells is medi-ated by NPY and 5-HT2B receptors via ERK1/2 signalling path-ways. Cell Prolif 2009; 42: 571-586.
    • (2009) Cell Prolif , vol.42 , pp. 571-586
    • Jin, H.K.1    Bae, J.S.2    Furuya, S.3    Carter, J.E.4
  • 69
    • 73149105318 scopus 로고    scopus 로고
    • Laminin-1 induces neurite outgrowth in human mesen-chymal stem cells in serum/differentiation factors-free conditions through activation of FAK-MEK/ERK signaling pathways
    • Mruthyunjaya S, Manchanda R, Godbole R, Pujari R, Shiras A, Shastry P. Laminin-1 induces neurite outgrowth in human mesen-chymal stem cells in serum/differentiation factors-free conditions through activation of FAK-MEK/ERK signaling pathways. Bio-chem Biophys Res Commun 2010; 391: 43-8.
    • (2010) Bio-chem Biophys Res Commun , vol.391 , pp. 43-48
    • Mruthyunjaya, S.1    Manchanda, R.2    Godbole, R.3    Pujari, R.4    Shiras, A.5    Shastry, P.6
  • 70
    • 27544461403 scopus 로고    scopus 로고
    • ERK signaling pathways regulate the osteogenic differentiation of human mesenchymal stem cells on collagen I and vitronectin
    • Salasznyk RM, Klees RF, Hughlock MK, Plopper GE. ERK signal-ing pathways regulate the osteogenic differentiation of human mes-enchymal stem cells on collagen I and vitronectin. Cell Commun Adhes 2004; 11: 137-153.
    • (2004) Cell Commun Adhes , vol.11 , pp. 137-153
    • Salasznyk, R.M.1    Klees, R.F.2    Hughlock, M.K.3    Plopper, G.E.4
  • 71
    • 42649083295 scopus 로고    scopus 로고
    • ERK2 protein regulates the proliferation of human mesenchymal stem cells without affecting their mobilization and differentiation potential
    • Cárcamo-Orive I, Tejados N, Delgado J, et al. ERK2 protein regulates the proliferation of human mesenchymal stem cells without affecting their mobilization and differentiation potential. Exp Cell Res. 2008; 314: 1777-88.
    • (2008) Exp Cell Res , vol.314 , pp. 1777-1788
    • Cárcamo-Orive, I.1    Tejados, N.2    Delgado, J.3
  • 72
    • 77953935060 scopus 로고    scopus 로고
    • Serum regulates adipogenesis of mesenchymal stem cells via MEK/ERK dependent PPARgamma expression and phosphorylation
    • Wu L, Cai X, Dong H, et al. Serum regulates adipogenesis of mes-enchymal stem cells via MEK/ERK dependent PPARgamma ex-pression and phosphorylation. J Cell Mol Med 2010; 14(4): 922-932.
    • (2010) J Cell Mol Med , vol.14 , Issue.4 , pp. 922-932
    • Wu, L.1    Cai, X.2    Dong, H.3
  • 73
    • 70350243075 scopus 로고    scopus 로고
    • Introducing transcription factors to multipotent mesenchymal stem cells: Making transdifferentiation possible
    • Barzilay R, Melamed E, Offen D. Introducing transcription factorsto multipotent mesenchymal stem cells: making transdifferentiationpossible. Stem Cells 2009; 27: 2509-15.
    • (2009) Stem Cells , vol.27 , pp. 2509-2515
    • Barzilay, R.1    Melamed, E.2    Offen, D.3
  • 74
    • 46449113364 scopus 로고    scopus 로고
    • The tumorigenicity of human embryonicstem cells
    • Blum B, Benvenisty N. The tumorigenicity of human embryonicstem cells. Adv Cancer Res 2008; 100: 133-58.
    • (2008) Adv Cancer Res , vol.100 , pp. 133-1358
    • Blum, B.1    Benvenisty, N.2
  • 75
    • 51849111566 scopus 로고    scopus 로고
    • Fibroblast growth Factor-2 and -4 Promote the Proliferation of Bone Marrowmesenchymal Stem Cells By the Activation of the PI3K-Akt AndERK1/2 Signaling Pathways
    • Choi SC, Kim SJ, Choi JH, Park CY, Shim WJ, Lim DS. Fibroblast growth factor-2 and -4 promote the proliferation of bone marrowmesenchymal stem cells by the activation of the PI3K-Akt andERK1/2 signaling pathways. Stem Cells Dev 2008; 17: 725-736.
    • (2008) Stem Cells Dev , vol.17 , pp. 725-736
    • Choi, S.C.1    Kim, S.J.2    Choi, J.H.3    Park, C.Y.4    Shim, W.J.5    Lim, D.S.6
  • 76
    • 33645392225 scopus 로고    scopus 로고
    • Gene transfer into rat mesenchymal stem cells: A comparative study of viral and nonviral vectors
    • McMahon JM, Conroy S, Lyons M, et al. Gene transfer into rat mesenchymal stem cells: a comparative study of viral and nonviral vectors. Stem Cells Dev 2006; 15: 87-96.
    • (2006) Stem Cells Dev , vol.15 , pp. 87-96
    • McMahon, J.M.1    Conroy, S.2    Lyons, M.3
  • 77
    • 53249090261 scopus 로고    scopus 로고
    • Retrovirus-induced oncogenesis and safety of retroviral vectors
    • Nair V. Retrovirus-induced oncogenesis and safety of retroviral vectors. Curr Opin Mol Ther 2008; 10: 431-8.
    • (2008) Curr Opin Mol Ther , vol.10 , pp. 431-438
    • Nair, V.1
  • 78
    • 66049135249 scopus 로고    scopus 로고
    • Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins
    • Zhou H, Wu S, Joo JY, et al. Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins. Cell Stem Cell 2009; 4:381-4.
    • (2009) Cell Stem Cell , vol.4 , pp. 381-384
    • Zhou, H.1    Wu, S.2    Joo, J.Y.3
  • 79
    • 77950899350 scopus 로고    scopus 로고
    • Monitoring the genomic stability of in vitro cultured rat bone marrow-derived mesenchymal stem cells
    • Foudah D, Redaelli S, Bentivegna A, Miloso M, Tredici G. Monitoring the genomic stability of in vitro cultured rat bone marrow-derived mesenchymal stem cells. Chromosome Res 2009; 17:1025-39.
    • (2009) Chromosome Res , vol.17 , pp. 1025-1039
    • Foudah, D.1    Redaelli, S.2    Bentivegna, A.3    Miloso, M.4    Tredici, G.5
  • 80
    • 18144380142 scopus 로고    scopus 로고
    • Bone marrow-derivedmesenchymal stem cells already express specific neural proteinsbefore any differentiation
    • Tondreau T, Lagneaux L, Dejeneffe M, et al. Bone marrow-derivedmesenchymal stem cells already express specific neural proteinsbefore any differentiation. Differentiation 2004; 72: 319-26.
    • (2004) Differentiation , vol.72 , pp. 319-326
    • Tondreau, T.1    Lagneaux, L.2    Dejeneffe, M.3
  • 81
    • 0030948207 scopus 로고    scopus 로고
    • Mechanically regulated expression of a neural glutamate transporter in bone: A role for ex-citatory amino acids as osteotropic agents?
    • Mason DJ, Suva LJ, Genever PG, et al. Mechanically regulatedexpression of a neural glutamate transporter in bone: a role for ex-citatory amino acids as osteotropic agents? Bone 1997; 20: 199-205.
    • (1997) Bone , vol.20 , pp. 199-205
    • Mason, D.J.1    Suva, L.J.2    Genever, P.G.3
  • 82
    • 21244432845 scopus 로고    scopus 로고
    • Neuronal differentiation of bone marrow-derived stromal stem cells involves suppression of discordant phenotypes through gene silencing
    • Egusa H, Schweizer FE, Wang CC, Matsuka Y, Nishimura I. Neu-ronal differentiation of bone marrow-derived stromal stem cells in-volves suppression of discordant phenotypes through gene silenc-ing. J Biol Chem 2005; 280: 23691-7.
    • (2005) J Biol Chem , vol.280 , pp. 23691-23697
    • Egusa, H.1    Schweizer, F.E.2    Wang, C.C.3    Matsuka, Y.4    Nishimura, I.5
  • 83
    • 0033675165 scopus 로고    scopus 로고
    • Neurohormones and catecholamines as functional components of the bone marrow microenvironment
    • Maestroni GJ. Neurohormones and catecholamines as functionalcomponents of the bone marrow microenvironment. Ann N Y AcadSci 2000; 917: 29-37.
    • (2000) Ann N Y Acad Sci , vol.917 , pp. 29-37
    • Maestroni, G.J.1
  • 84
    • 0032916126 scopus 로고    scopus 로고
    • Expression of neurotrophins and their receptors in human bone marro
    • Labouyrie E, Dubus P, Groppi A, et al. Expression of neurotro-phins and their receptors in human bone marrow. Am J Pathol 1999; 154: 405-415.
    • (1999) Am J Patho , vol.15 , pp. 405-415
    • Labouyrie, E.1    Dubus, P.2    Groppi, A.3
  • 85
    • 0025217169 scopus 로고
    • Ultrastructural morphometric study of efferent nerve terminals on murine bone marrow stromal cells, and the recognition of a novel anatomical unit: The neuro-reticular complex
    • Yamazaki K, Allen TD. Ultrastructural morphometric study of efferent nerve terminals on murine bone marrow stromal cells, andthe recognition of a novel anatomical unit: the neuro-reticularcomplex. Am J Anat 1990; 187: 261-76.
    • (1990) Am J Anat , vol.187 , pp. 261-276
    • Yamazaki, K.1    Allen, T.D.2
  • 86
    • 10744233814 scopus 로고    scopus 로고
    • Electrophysiological properties of human mesenchymal stem cells
    • Heubach JF, Graf EM, Leutheuser J, et al. Electrophysiological properties of human mesenchymal stem cells. J Physiol 2004; 554:659-72.
    • (2004) J Physiol , vol.554 , pp. 659-672
    • Heubach, J.F.1    Graf, E.M.2    Leutheuser, J.3
  • 87
    • 0036239076 scopus 로고    scopus 로고
    • Neural stem cells: Form and function
    • Reh TA. Neural stem cells: form and function. Nat Neurosci 2002;5: 392-4.
    • (2002) Nat Neurosci , vol.5 , pp. 392-394
    • Reh, T.A.1
  • 88
    • 33749236055 scopus 로고    scopus 로고
    • Adult mesenchymal stem cellsrescue dorsal root ganglia neurons from dying
    • Scuteri A, Cassetti A, Tredici G. Adult mesenchymal stem cellsrescue dorsal root ganglia neurons from dying. Brain Res 2006;1116: 75-81.
    • (2006) Brain Res , vol.1116 , pp. 75-81
    • Scuteri, A.1    Cassetti, A.2    Tredici, G.3
  • 89
    • 52949150765 scopus 로고    scopus 로고
    • Adult mesenchymalstem cells support cisplatin-treated dorsal root ganglion survival
    • Scuteri A, Donzelli E, Ravasi M, Tredici G. Adult mesenchymalstem cells support cisplatin-treated dorsal root ganglion survival. Neurosci Lett 2008; 445: 68-72.
    • (2008) Neurosci Lett , vol.445 , pp. 68-72
    • Scuteri, A.1    Donzelli, E.2    Ravasi, M.3    Tredici, G.4
  • 90
    • 32644434557 scopus 로고    scopus 로고
    • Human mesenchymal stem cell subpopulations express a variety of neuro regulatory molecules and promote neuronal cell survival and neuritogenesis
    • Crigler L, Robey RC, Asawachaicharn A, Gaupp D, Phinney DG. Human mesenchymal stem cell subpopulations express a variety ofneuro-regulatory molecules and promote neuronal cell survival andneuritogenesis. Exp Neurol 2006; 198: 54-64.
    • (2006) Exp Neurol , vol.198 , pp. 54-64
    • Crigler, L.1    Robey, R.C.2    Asawachaicharn, A.3    Gaupp, D.4    Phinney, D.G.5
  • 92
    • 0036118625 scopus 로고    scopus 로고
    • Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats
    • Zhao LR, Duan WM, Reyes M, Keene CD, Verfaillie CM, Low WC. Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats. Exp Neurol 2002; 174: 11-20.
    • (2002) Exp Neurol , vol.174 , pp. 11-20
    • Zhao, L.R.1    Duan, W.M.2    Reyes, M.3    Keene, C.D.4    Verfaillie, C.M.5    Low, W.C.6
  • 93
    • 33745456034 scopus 로고    scopus 로고
    • Implantation of BM mesenchymal stem cells into injured spinal cord elicits denovo neurogenesis and functional recovery: Evidence from a study in rhesus mokeys
    • Deng YB, Liu XG, Liu ZG, Liu XL, Liu Y, Zhou GQ. Implantation of BM mesenchymal stem cells into injured spinal cord elicits denovo neurogenesis and functional recovery: evidence from a study in rhesus mokeys. Cytotherapy 2006; 8: 210-4.
    • (2006) Cytotherapy , vol.8 , pp. 210-214
    • Deng, Y.B.1    Liu, X.G.2    Liu, Z.G.3    Liu, X.L.4    Liu, Y.5    Zhou, G.Q.6
  • 94
    • 33847309067 scopus 로고    scopus 로고
    • Transplantation of bone marrow stromal cells for peripheral nerve repair
    • Chen CJ, Ou YC, Liao SL, et al. Transplantation of bone marrow stromal cells for peripheral nerve repair. Exp Neurol 2007; 204:443-453.
    • (2007) Exp Neurol , vol.204 , pp. 443-453
    • Chen, C.J.1    Ou, Y.C.2    Liao, S.L.3
  • 95
    • 0036789359 scopus 로고    scopus 로고
    • Peripheral nerve regeneration by bone marrow stromal cells
    • Cuevas P, Carceller F, Dujovny M, et al. Peripheral nerve regeneration by bone marrow stromal cells. Neurol Res 2002; 24: 634-8.
    • (2002) Neurol Res , vol.24 , pp. 634-638
    • Cuevas, P.1    Carceller, F.2    Dujovny, M.3
  • 97
    • 29144460856 scopus 로고    scopus 로고
    • Human stem/progenitor cells from bone marrow promote neurogenesis of endogenous neural stem cells in the hippocampus of mice
    • Munoz JR, Stoutenger BR, Robinson AP, Spees JL, Prockop DJ. Human stem/progenitor cells from bone marrow promote neuro-genesis of endogenous neural stem cells in the hippocampus of mice. Proc Natl Acad Sci USA 2005; 102: 18171-6.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 18171-18176
    • Munoz, J.R.1    Stoutenger, B.R.2    Robinson, A.P.3    Spees, J.L.4    Prockop, D.J.5
  • 98
    • 37549053263 scopus 로고    scopus 로고
    • Biochemical heterogeneity of mesenchymal stem cell populations: Clues to their therapeutic efficacy
    • Phinney DG. Biochemical heterogeneity of mesenchymal stem cellpopulations: clues to their therapeutic efficacy. Cell Cycle 2007; 6:2884-9.
    • (2007) Cell Cycle , vol.6 , pp. 2884-2889
    • Phinney, D.G.1
  • 99
    • 0034056758 scopus 로고    scopus 로고
    • Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to ahierarchical model
    • Muraglia A, Cancedda R, Quarto R. Clonal mesenchymal progeni-tors from human bone marrow differentiate in vitro according to ahierarchical model. J Cell Sci 2000; 113: 1161-6.
    • (2000) J Cell Sci , vol.113 , pp. 1161-1166
    • Muraglia, A.1    Cancedda, R.2    Quarto, R.3
  • 100
    • 46749133147 scopus 로고    scopus 로고
    • Variations of clonal marrowstem cell lines established from human bone marrow in surface epitopes, differentiation potential, gene expression, and cytokine secretion
    • Song SU, Kim CS, Yoon SP, et al. Variations of clonal marrowstem cell lines established from human bone marrow in surface epi-topes, differentiation potential, gene expression, and cytokine se-cretion. Stem Cells Dev 2008; 17: 451-61.
    • (2008) Stem Cells Dev , vol.17 , pp. 451-461
    • Song, S.U.1    Kim, C.S.2    Yoon, S.P.3
  • 101
    • 34250854663 scopus 로고    scopus 로고
    • Neuroepithelial cells supply an initial transient wave of MSC differentiation
    • Takashima Y, Era T, Nakao K, et al. Neuroepithelial cells supply an initial transient wave of MSC differentiation. Cell 2007; 129:1377-88.
    • (2007) Cell , vol.129 , pp. 1377-1388
    • Takashima, Y.1    Era, T.2    Nakao, K.3
  • 102
    • 33845547990 scopus 로고    scopus 로고
    • Transdifferentiated mesenchymal stem cells as alternative therapy in supportingnerve regeneration and myelination
    • Keilhoff G, Stang F, Goihl A, Wolf G, Fansa H. Transdifferentiated mesenchymal stem cells as alternative therapy in supportingnerve regeneration and myelination. Cell Mol Neurobiol 2006; 26:1235-52.
    • (2006) Cell Mol Neurobiol , vol.26 , pp. 1235-1252
    • Keilhoff, G.1    Stang, F.2    Goihl, A.3    Wolf, G.4    Fansa, H.5
  • 103
    • 30344440721 scopus 로고    scopus 로고
    • Transdifferentiation of mesenchymal stem cells into Schwann cell-like myelinating cells
    • Keilhoff G, Goihl A, Langnäse K, Fansa H, Wolf G. Transdifferen-tiation of mesenchymal stem cells into Schwann cell-like myelinat-ing cells. Eur J Cell Biol 2006; 85: 11-24.
    • (2006) Eur J Cell Biol , vol.85 , pp. 11-24
    • Keilhoff, G.1    Goihl, A.2    Langnäse, K.3    Fansa, H.4    Wolf, G.5
  • 104
    • 2442425936 scopus 로고    scopus 로고
    • Rat bone marrow mesenchymal stem cells express glial markers and stimulate nerve regeneration
    • Tohill M, Mantovani C, Wiberg M, Terenghi G. Rat bone marrow mesenchymal stem cells express glial markers and stimulate nerve regeneration. Neurosci Lett 2004; 362: 200-3.
    • (2004) Neurosci Lett , vol.362 , pp. 200-203
    • Tohill, M.1    Mantovani, C.2    Wiberg, M.3    Terenghi, G.4
  • 105
    • 64249119860 scopus 로고    scopus 로고
    • Characterisation of human mesenchymal stem cells following differentiation into Schwann cell-like cells
    • Brohlin M, Mahay D, Novikov LN, et al. Characterisation of hu-man mesenchymal stem cells following differentiation into Schwann cell-like cells. Neurosci Res 2009; 64: 41-9.
    • (2009) Neurosci Res , vol.64 , pp. 41-49
    • Brohlin, M.1    Mahay, D.2    Novikov, L.N.3
  • 106
    • 55749098498 scopus 로고    scopus 로고
    • Stem/progenitor cells from bone marrow decrease neuronal death in global ischemia by modulation of inflammatory/immune responses
    • Ohtaki H, Ylostalo JH, Foraker JE, et al. Stem/progenitor cells from bone marrow decrease neuronal death in global ischemia by modulation of inflammatory/immune responses. Proc Natl AcadSci USA 2008; 105: 14638-43.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14638-14643
    • Ohtaki, H.1    Ylostalo, J.H.2    Foraker, J.E.3
  • 107
    • 65649113921 scopus 로고    scopus 로고
    • Human bone marrow-derived mesenchymal stem cells induce Th2-polarized immune response and promote endogenous repair in animal models of multiple sclerosis
    • Bai L, Lennon DP, Eaton V, et al. Human bone marrow-derived mesenchymal stem cells induce Th2-polarized immune response and promote endogenous repair in animal models of multiple sclerosis. Glia 2009; 57: 1192-203.
    • (2009) Glia , vol.57 , pp. 1192-1203
    • Bai, L.1    Lennon, D.P.2    Eaton, V.3
  • 108
    • 68949209290 scopus 로고    scopus 로고
    • Neuroprotective mesenchymal stem cells are endowed with a potent antioxidant effect in vivo
    • Lanza C, Morando S, Voci A, et al. Neuroprotective mesenchymal stem cells are endowed with a potent antioxidant effect in vivo. J Neurochem 2009; 110: 1674-84.
    • (2009) J Neurochem , vol.110 , pp. 1674-1684
    • Lanza, C.1    Morando, S.2    Voci, A.3
  • 109
    • 23944519424 scopus 로고    scopus 로고
    • Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy
    • Zappia E, Casazza S, Pedemonte E, et al. Mesenchymal stem cellsameliorate experimental autoimmune encephalomyelitis inducingT-cell anergy. Blood 2005; 106: 1755-61.
    • (2005) Blood , vol.106 , pp. 1755-1761
    • Zappia, E.1    Casazza, S.2    Pedemonte, E.3
  • 110
    • 34147126415 scopus 로고    scopus 로고
    • Mesenchymal stem cells effectively modulate pathogenic immune response in experimental autoimmune encephalomyelitis
    • Gerdoni E, Gallo B, Casazza S, et al. Mesenchymal stem cells effectively modulate pathogenic immune response in experimental autoimmune encephalomyelitis. Ann Neurol 2007; 61: 219-227.
    • (2007) Ann Neurol , vol.61 , pp. 219-227
    • Gerdoni, E.1    Gallo, B.2    Casazza, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.