Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors

Nature

Volumn 386, Issue 6627, 1997, Pages 833-838

  Leonardo, E David ^a   Hinck, Lindsay ^a   Masu, Masayuki ^a   Keino Masu, Kazuko ^a,b   Ackerman, Susan L ^c   Tessier Lavigne, Marc ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^c JACKSON LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOATTRACTANT;

ARTICLE; CAENORHABDITIS ELEGANS; CELL MIGRATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

EID: 0030888324     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/386833a0     Document Type: Article

References (32)

1. Ishii, N., Wadsworth, W. G., Stern, B. D., Culotti, J. G. & Hedgecock, E. M. UNC-6, a laminin related protein, guides cells and pioneer axon migrations in C. elegans. Neuron 9, 873-881 (1992).
2. Serafini, T. et al. The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6. Cell 78, 409-424 (1994).
3. Kennedy, T. E., Serafini, T., de la Torre, J. R. & Tessier-Lavigne, M. Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord. Cell 78, 425-435 (1994).
4. Colamarino, S. A. & Tessier-Lavigne, M. The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons. Cell 81, 621-629 (1995).
5. Shirasaki, R., Tamada, A., Katsumata, R. & Murakami, F. Guidance of cerebellofugal axons in the rat embryo: directed growth toward the floor plate and subsequent elongation along the longitudinal axis. Neuron 14, 961-972 (1995).
6. Wadsworth, W. G., Bhatt, H. & Hedgecock, E. M. Neuroglia and pioneer neurons express UNC-6 to provide global and local netrin cues for guiding migrations in C. elegans. Neuron 16, 35-46 (1996).
7. Mitchell, K. J. et al. Genetic analysis of Netrin genes in Drosophila: Netrins guide CNS commissural axons and peripheral motor axons. Neuron 17, 203-215 (1996).
8. Harris, R., Sabatelli, L. M. & Seeger, M. A. Guidance cues at the Drosophila CNS midline: identification and characterization of two Drosophila Netrin/UNC-6 homologs. Neuron 17, 217-228 (1996).
9. Serafini, T. et al. Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system. Cell 87, 1001-1014 (1996).
10. Shirasaki, R., Mirzayan, C., Tessier-Lavigne, M. & Murakami, F. Guidance of circumferentially growing axons by netrin-dependent and -independent floor plate chemotropism in the vertebrate brain. Neuron 17, 1079-1088 (1996).
11. Chan, S. S.-Y. et al. UNC-40, a C. elegans homolog of DCC (Deleted in Colorectal Cancer), is required in motile cells responding to UNC-6 netrin cues. Cell 87, 187-195 (1996).
12. Kolodziej, P. A. et al. frazzled encodes a Drosophila member of the DCC immunoglobulin subfamily and is required for CNS and motor axon guidance. Cell 87, 197-204 (1996).
13. Keino-Masu, K. et al. Deleted in Colorectal Cancer (DCC) encodes a netrin receptor. Cell 87, 175-185 (1996).
14. Leung-Hagesteijn, C. et al. UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C elegans. Cell 71, 289-299 (1992).
15. Fazeli, A. et al. Phenotype of mice lacking functional Deleted in Colorectal Cancer (DCC) gene. Nature 386, 796-804 (1997).
16. Hedgecock, E. M., Culotti, J. G. & Hall, D. H. The unc-5, unc-6 and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans. Neuron 2, 61-85 (1990).
17. McIntire, S. L., Garriga, G., White, J., Jacobson, D. & Horvitz, H. R. Genes necessary for directed axonal elongation or fasciculation in C. elegans. Neuron 8, 307-322 (1992).
18. Hamelin, M., Zhou, Y., Su, M. W., Scott, I. M. & Culotti, J. G. Expression of the UNC-5 guidance receptor in the touch neurons of C. elegans steers their axons dorsally. Nature 364, 327-330 (1993).
19. Ackerman, S. L. et al. The mouse rostral cerebellar malformation gene encodes an UNC-5 like protein. Nature 386, 838-842 (1997).
20. Willott, E. et al. The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions. Proc. Natl Acad. Sci. USA 90, 7834-7838 (1993).
21. Itoh, M. et al. The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy. J. Cell Biol. 121, 491-502 (1993).
22. Sheng, M. PDZs and receptor/channel clustering: rounding up the latest suspects. Neuron 17, 575-578 (1996).
23. Altman, J. & Bayer, S. A. The development of the rat spinal cord. Adv. Anat. Embryol. Cell Biol. 85, 1-166 (1984).
24. Ramón y Cajal, S. Histologie du Système Nerveux de l'Homme at des Vertébrés Vol. 2 (Maloine, Paris, 1911).
25. Rakic, P. Neuron-glia relationship during granule cell migration in developing cerebellar cortex. A Golgi and electron microscopic study in Macacus rhesus. J. Comp. Neurol. 141, 283-312 (1971).
26. Klar, A., Baldassare, M. & Jessell, T. M. F-spondin: a gene expressed at high levels in the floor plate encodes a secreted protein that promotes neural cell adhesion and neurite extension. Cell 69, 95-110 (1992).
27. Messersmith, E. K. et al. Semaphorin III can function as a selective chemorepellent to pattern sensory projections in the spinal cord. Neuron 14, 949-959 (1995).
28. Luo, Y., Raible, D. & Raper, J. A. Collapsin: a protein in brain that induces the collapse and paralysis of neuronal growth cones. Cell 75, 217-227 (1993).
29. Guthrie, S. & Pini, A. Chemorepulsion of developing motor axons by the floor plate. Neuron 14, 1117-1130 (1995).
30. Varela-Echavarria, A., Tucker, A., Puschel, A. & Guthrie, S. Motor axon subpopulations respond differentially to the chemorepellents netrin-1 and semaphorin D. Neuron 18, 193-207 (1997).
31. Livesey, F. J. & Hunt, S. P. Netrin and netrin receptor expression in the embryonic mammalian nervous system suggests role in retinal, striatal, nigral and cerebellar development. Mol. Cell. Neurosci. (in the press). UPDATE?
32. Evan, G. I., Lewis, G. K., Ramsay, G. & Bishop, J. M. Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol. Cell. Biol. 5, 3610-3616 (1985).