Up-regulation of ephrin-a1 during melanoma progression

International Journal of Cancer

Volumn 84, Issue 5, 1999, Pages 494-501

  Easty, David J ^a   Hill, Simon P ^a   Hsu, Mei Yu ^a   Fallowfield, Mary E ^a   Ftorenes, Vivi Ann ^a   Herlyn, Meenhard ^a   Bennett, Dorothy C ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; EPHRIN A1; EPHRIN RECEPTOR A2; MEMBRANE PROTEIN; MESSENGER RNA; PROTEIN;

ARTICLE; BIOSYNTHESIS; CELL CULTURE; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; MELANOMA; METABOLISM; PATHOLOGY; PROTEIN SYNTHESIS; UPREGULATION;

CYTOKINES; EPHRIN-A1; HUMANS; IMMUNOHISTOCHEMISTRY; MELANOMA; MEMBRANE PROTEINS; PROTEIN BIOSYNTHESIS; PROTEINS; RECEPTOR, EPHA2; RNA, MESSENGER; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0033595651     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-0215(19991022)84:5<494::aid-ijc8>3.0.co;2-o     Document Type: Article

References (35)

1. HARTLEY, T.D. and 19 OTHERS, B61 is a ligand for the ECK receptor protein-tyrosine kinase. Nature (Land.), 368, 558-560 (1994).
2. CLARK, W.H., JR., ELDER, D.E., GUERRY, D., EPSTEIN, M.N., GREENE, M.H. and HORN, M., A study of tumor progression: the precursor lesions of superficial spreading and nodular melanoma. Hum. Pathol., 15, 1147-1165 (1984).
3. DAVIS, S., GALE, N.W., ALDRICH, T.H., MAISONPIERRE, P.C., LHOTAK, V., PAWSON, T., GOLDFARB, M. and YANCOPOULOS, G.D., Ligands for EPH receptor tyrosine kinases that require membrane attachment or clustering for activity. Science, 266, 816-819 (1994).
4. DRESCHER, U., The Eph family in the patterning of neural development. Curr. Biol, 7, R799-R807 (1997).
5. EASTY, D.J., GANZ, S.E., FARR, C.J., LAI, C., HERLYN, M. and BENNETT, D.C., Novel and known protein tyrosine kinases and their abnormal expression in human melanoma. J. invest. Dennatol., 101, 679-684 (1993).
6. EASTY, D.J., GUTHRIE, B.A., MAUNG, K., FARR, C.J., LINDBERG, R.A., Toso, R.J., HERLYN, M. and BENNETT, D.C., Protein B61 as a new growth factor: expression of B61 and upregulation of its receptor epithelial cell kinase during melanoma progression. Cancer Res., 55, 2528-2532 (1995a).
7. EASTY, D.J., HERLYN, M. and BENNETT, D.C., Abnormal protein tyrosine kinase gene expression during melanoma progression and metastasis. Int. J. Cancer, 60, 129-136(19950).
8. EASTY, D.J., MAUNG, K., LASCU, I., VERNON, M., FALLOWFIELD, M.E., HART, I.R. and BENNETT, D.C., Expression of NM23 in human melanoma progression and metastasis. Brit. J. Cancer, 74, 109-114 (1996).
9. EASTY, D.J., MITCHELL, P.J., PATEL, K., FLORENES, V.A., SPRITZ, R.A. and BENNETT, D.C., Loss of expression of receptor tyrosine kinase family genes PTK7 and SEK in metastatic melanoma. /;;J. J. Cancer, 71, 1061-1065 (1997).
10. EPH NOMENCLATURE COMMITTEE, United nomenclature for Eph family receptors and their ligands, the ephrins. Cell, 90, 403-104 (1998).
11. FLORENES, V.A., AAMDAL, S., MYKLEBOST, O., MAELANDSMO, G.M., BRULAND, O.S. and FODSTAD, O., Levels of nm23 messenger RNA in metastatic malignant melanomas: inverse correlation to disease progression. Cancer Res., 52, 6088-6091(1992).
12. HANAHAN, D. and FOLKMAN, J., Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell, 86, 353-364 (1996).
13. HERLYN, D., ILIOPOULOS, D., JENSEN, P.J., PARMITER, A., BAIRD, J., HOTLA, H., Ross, A.H., JAMBROSIC, J., KOPROWSKI, H. and HERLYN, M., In vitro properties of human melanoma cells metastatic in nude mice. Cancer Res., 50, 2296-2302(1990).
14. HOLZMAN, L.B., MARKS, R.M. and DIXIT, V.M., A novel immediate-early response gene of endothelium is induced by cytokines and encodes a secreted protein. Mol. cell. Bio!., 10, 5830-5838 (1990).
15. Hsu, M.-Y. and HERLYN, M., Cultivation of normal human epidermal melanocytes. In: G.E. Jones (ed.), Methods in molecular medicine. Human cell culture protocols, p. 9-20, Humana Press, Totowa, NJ ( 1998).
16. IWAMOTO, T., TAKAHASHI, M., ITO, M., HAMATANI, K., OHBAYASHI, M., WAJJWALKU, W., ISOBE, K.-I. and NAKASHIMA, I., Aberrant melanogenesis and melanocytic tumor development in transgenic mice that carry a metallothionein/rf / fusion gene. EM BO J., 10, 3167-3175 ( 1991 ).
17. JUHASZ, I., ALBEDA, S.M., ELDER, D.E., MURPHY, G.F., ADACHI, K., HERLYN, D., VALYI-NAOY, I.T. and HERLYN, M., Growth and invasion of human skin grafted to immunodeficient mice. Amer. J. Palhol, 143, 528-537 (1993).
18. KOBAYASHI, H., MAN, S., MACUOUGALL, J.R., GRAHAM, C.H., Lu, C. and KERBEL, R.S., Variant sublines of earlystage human melanomas selected for tumorigenicity in nude mice express a multicytokine-resistant phenotype. Amer. J. Pathol, 144, 776-786 (1994).
19. LAI, C. and LEMKE, G., An extended family of protein tyrosine-kinase genes differentially expressed in the vertebrate nervous system. Neuron, 6, 691-704(1991).
20. LASSAM, N. and BICKFORD, S., Loss of c-kit expression in cultured melanoma cells. Oncogene, 7, 51-56 (1992).
21. LEE, ST., STRUNK, K.M. and SPRITZ, R.A., A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes. Oncogene, 8, 3403-3410(1993).
22. LINDBERG, R. and HUNTER, T., cDNA cloning and characterisation of eck, an epithelial cell receptor tyrosine kinase in the epli/elk family of protein kinases. Mol. cell. Biol., 10, 6316-6324 (1990).
23. MAGAL, E., HOLLASH, J.A., Toso, R.J., CHANG, D., LINDBERG, R.A. and PASQUALE, E.B., B61, a ligand for the Eck receptor protein-tyrosine kinase, exhibits neurotrophic activity in cultures of rat spinal cord neurons. J. Neurosci. Res., 43, 735-744 (1996).
24. MALITSCHEK, B., FORNZLER, D. and SCHARTL, M., Melanoma formation in Xiphophoms: a model system for the role of receptor tyrosine kinases in tumorigenesis. Bioessays, 17, 1017-1023(1995).
25. MARU, Y., HIRAI, H. and TAKAKU, F., Over-expression confers an oncogenic potential upon the eph gene. Oncogene, 5, 445-147 (1990).
26. NATALI, P.O., NICOTRA, M.R., WINKLER, A.B., CAVALIERE, R., BIGOTTI, A. and ULLRICH, A., Progression of human cutaneous melanoma is associated with loss of expression of c-kit protooncogene receptor. Int. J. Cancer, 52, 197-201 (1992).
27. PANDEY, A., LINDBERG, R.A. and DIXIT, V., Receptor orphans find a family. Cell Biol., 5, 986-989 (1995a).
28. PANDEY, A., SHAO, H., MARKS, R.M., POLVERINI, P.J. and DIXIT, V.M., Role of B61, the licand for the Eck receptor tyrosine kinase, in TNF-α-induced angiogenesis.Science, 268, 567-569 (1995b).
29. PASQUALE, E.B., The Eph family of receptors. Girr. Opin. Cell Biol., 9, 608-615(1997).
30. RAK, J.W., ST. CROIX, D.B. and KERBEL, R.S., Consequences of angiogenesis for tumor progression, metastasis, and cancer therapy. Anti-Cancer Drugs, 6, 3-18(1995).
31. RODECK, U. and HERLYN, M., Growth factors in melanoma. Cancer Metastasis Rev.. 10, 89-101 (1991).
32. ROSENBERG, I.M., GOKE, M., KANI, M., REINECKER, H.-C. and POLDOLSKY, O.K., Epithelial cell kinase-B61: an autocrine loop modulating intestinal epithelial migration and barrier function. Amer. J. Physiol, 272, G824-G832(1997).
33. VAN DER GEER, P., HUNTER, T. and LINDBERG, R.A., Receptor protein tyrosine kinases and their signal transduction pathways. Ann. Rev. Cell Biol., 10, 257-337(1994).
34. VOGT, T., STOLZ, \V., WELSH, J., JUNG, B., KERBEL, R.S., KOBAYASHI, H., LANDTHALER, M. and MCCLELLAND, M., Over-expression of Lerk-5/Eplg5 messenger RNA: a novel marker for increased tumorigenicity and metastatic potential in human malignant melanomas. Clin. Cancer Res., 4, 791-797(1998).
35. WiLCOX, J., Fundamental principles of in situ hybridization. J. Histochem. Cytochem., 41, 1721-1723 (1993).