-
1
-
-
0036310316
-
The role of tumor lymphangiogenesis in metastatic spread
-
Stacker SA, Baldwin ME, Achen MG. The role of tumor lymphangiogenesis In metastatic spread. FASEB J 2002;16:922-34.
-
(2002)
FASEB J
, vol.16
, pp. 922-934
-
-
Stacker, S.A.1
Baldwin, M.E.2
Achen, M.G.3
-
2
-
-
1242269816
-
Role of lymphangiogenic factors in tumor metastasis
-
He Y, Karpanen T, Alitalo K. Role of lymphangiogenic factors in tumor metastasis, Biochim Biophys Acta 2004;1654:3-12.
-
(2004)
Biochim Biophys Acta
, vol.1654
, pp. 3-12
-
-
He, Y.1
Karpanen, T.2
Alitalo, K.3
-
3
-
-
0036673666
-
Metastasis: Lymphangiogenesis and cancer metastasis
-
Stacker SA, Achen MG, Jussila L, Baldwin ME, Alitalo K. Metastasis: Lymphangiogenesis and cancer metastasis. Nat Rev Cancer 2002;2:573-83.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 573-583
-
-
Stacker, S.A.1
Achen, M.G.2
Jussila, L.3
Baldwin, M.E.4
Alitalo, K.5
-
4
-
-
0036208217
-
The rediscovery of the lymphatic system: Old and new insights into the development and biological function of the lymphatic vasculature
-
Oliver G, Detmar M. The rediscovery of the lymphatic system: old and new insights into the development and biological function of the lymphatic vasculature. Genes Dev 2002;16:773-83.
-
(2002)
Genes Dev
, vol.16
, pp. 773-783
-
-
Oliver, G.1
Detmar, M.2
-
5
-
-
0030973506
-
Hyperplasia of lymphatic vessels in VEGF-C transgenic mice
-
Jeltsch M, Kaipainen A, Joukov V, et al. Hyperplasia of lymphatic vessels in VEGF-C transgenic mice, Science 1997;276:1423-5.
-
(1997)
Science
, vol.276
, pp. 1423-1425
-
-
Jeltsch, M.1
Kaipainen, A.2
Joukov, V.3
-
6
-
-
0031213636
-
VEGF and VEGF-C: Specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioal-lantoic membrane
-
Oh SJ, Jeltsch MM, Birkenhager R, et al. VEGF and VEGF-C: specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioal-lantoic membrane, Dev Biol 1997;188:96-109.
-
(1997)
Dev Biol
, vol.188
, pp. 96-109
-
-
Oh, S.J.1
Jeltsch, M.M.2
Birkenhager, R.3
-
7
-
-
17744396472
-
Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice
-
Velkkola T, Jussila L, Makinen T, et al. Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice. EMBO J 2001;20:1223-31.
-
(2001)
EMBO J
, vol.20
, pp. 1223-1231
-
-
Velkkola, T.1
Jussila, L.2
Makinen, T.3
-
8
-
-
0035970622
-
Adenoviral expression of vascular endothelial growth factor-CInduces lymphangiogenesis in the skin
-
Enholm B, Karpanen T, Jeltsch M, et al. Adenoviral expression of vascular endothelial growth factor-CInduces lymphangiogenesis in the skin, Circ Res 2001; 88:623-9.
-
(2001)
Circ Res
, vol.88
, pp. 623-629
-
-
Enholm, B.1
Karpanen, T.2
Jeltsch, M.3
-
9
-
-
0037120009
-
Lymphangiogenic gene therapy with minimal blood vascular side effects
-
Saaristo A, Veikkola T, Tammela T, et al. Lymphangiogenic gene therapy with minimal blood vascular side effects. J Exp Med 2002;196:719-30.
-
(2002)
J Exp Med
, vol.196
, pp. 719-730
-
-
Saaristo, A.1
Veikkola, T.2
Tammela, T.3
-
10
-
-
0035126049
-
VEGF-D promotes the metastatic spread of tumor cells via the lymphatics
-
Stacker SA, Caesar C, Baldwin ME, et al. VEGF-D promotes the metastatic spread of tumor cells via the lymphatics. Nat Med 2001;7:186-91.
-
(2001)
Nat Med
, vol.7
, pp. 186-191
-
-
Stacker, S.A.1
Caesar, C.2
Baldwin, M.E.3
-
11
-
-
0035122695
-
Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3
-
Makinen T. Jussila L, Veikkola T, et al. Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3. Nat Med 2001;7:199-205.
-
(2001)
Nat Med
, vol.7
, pp. 199-205
-
-
Makinen, T.1
Jussila, L.2
Veikkola, T.3
-
13
-
-
12244287614
-
Independent prognostic impact of lymphatic vessel density and presence of low-grade lymphangiogenesis in cutaneous melanoma
-
Straume O, Jackson DG, Akslen LA. Independent prognostic impact of lymphatic vessel density and presence of low-grade lymphangiogenesis in cutaneous melanoma. Clin Cancer Res 2003;9:250-6.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 250-256
-
-
Straume, O.1
Jackson, D.G.2
Akslen, L.A.3
-
14
-
-
0036494541
-
Intratumoral lymphangiogenesis and lymph node metastasis in head and neck cancer
-
Beasley NJ, Prevo R, Banerji S, et al. Intratumoral lymphangiogenesis and lymph node metastasis in head and neck cancer, Cancer Res 2002;62:1315-20.
-
(2002)
Cancer Res
, vol.62
, pp. 1315-1320
-
-
Beasley, N.J.1
Prevo, R.2
Banerji, S.3
-
15
-
-
6044232026
-
Lymphatic vessel density and vascular endothelial growth factor-C expression correlate with malignant behavior in human pancreatic endocrine tumors
-
Rubbia-Brandt L, Terris B, Giostra E, Dousset B, Morel P, Pepper MS. Lymphatic vessel density and vascular endothelial growth factor-C expression correlate with malignant behavior in human pancreatic endocrine tumors. Clin Cancer Res 2004;10: 6919-28.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 6919-6928
-
-
Rubbia-Brandt, L.1
Terris, B.2
Giostra, E.3
Dousset, B.4
Morel, P.5
Pepper, M.S.6
-
16
-
-
4644358551
-
Expression of lymphangiogenic factors and evidence of intratumoral lymphangiogenesis in pancreatic endocrine tumors
-
Sipos B, Klapper W, Kruse ML, Kalthoff H, Kerjaschki D, Kloppel G. Expression of lymphangiogenic factors and evidence of intratumoral lymphangiogenesis in pancreatic endocrine tumors. Am J Pathol 2004;65: 1187-97.
-
(2004)
Am J Pathol
, vol.65
, pp. 1187-1197
-
-
Sipos, B.1
Klapper, W.2
Kruse, M.L.3
Kalthoff, H.4
Kerjaschki, D.5
Kloppel, G.6
-
17
-
-
0035122537
-
Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis
-
Skobe M, Hawighorst T. Jackson DG, et al. Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis. Nat Med 2001;7:192-8.
-
(2001)
Nat Med
, vol.7
, pp. 192-198
-
-
Skobe, M.1
Hawighorst, T.2
Jackson, D.G.3
-
18
-
-
0035266283
-
Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth
-
Karpanen T, Egeblad M, Karkkainen MJ, et al. Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth. Cancer Res 2001;61:1786-90.
-
(2001)
Cancer Res
, vol.61
, pp. 1786-1790
-
-
Karpanen, T.1
Egeblad, M.2
Karkkainen, M.J.3
-
19
-
-
0037024472
-
Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling
-
He Y, Kozaki K, Karpanen T, et al. Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling, J Natl Cancer Inst 2002;94:819-25.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 819-825
-
-
He, Y.1
Kozaki, K.2
Karpanen, T.3
-
20
-
-
0037140120
-
VEGF-C induced lymphangio-genesis is associated with lymph node metastasis in orthotopic MCF-7 tumors
-
Mattila MM, Ruohola JK, Karpanen T, Jackson DG. Alitalo K, Harkonen PL. VEGF-C induced lymphangio-genesis is associated with lymph node metastasis in orthotopic MCF-7 tumors. Int J Cancer 2002;98:946-51.
-
(2002)
Int J Cancer
, vol.98
, pp. 946-951
-
-
Mattila, M.M.1
Ruohola, J.K.2
Karpanen, T.3
Jackson, D.G.4
Alitalo, K.5
Harkonen, P.L.6
-
21
-
-
0037079243
-
Thrombospondin-1 selectively inhibits early-stage cardnogenesis and anglogenesis but not tumor lymphangiogenesis and lymphatic metastasis in transgenic mice
-
Hawighorst T, Oura H, Streit M. et al. Thrombospondin-1 selectively inhibits early-stage cardnogenesis and anglogenesis but not tumor lymphangiogenesis and lymphatic metastasis in transgenic mice. Oncogene 2002; 21:7945-56.
-
(2002)
Oncogene
, vol.21
, pp. 7945-7956
-
-
Hawighorst, T.1
Oura, H.2
Streit, M.3
-
22
-
-
17744390184
-
Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis
-
Mandriota SJ, Jussila L, Jeltsch M, et al. Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis. EMBO J 2001;20:672-82.
-
(2001)
EMBO J
, vol.20
, pp. 672-682
-
-
Mandriota, S.J.1
Jussila, L.2
Jeltsch, M.3
-
23
-
-
2542512275
-
Preexisting lymphatic endothelium but not endothelial progenitor cells are essential for tumor lymphangiogenesis and lymphatic metastasis
-
He Y, Rajantie I, Ilmonen M, et al. Preexisting lymphatic endothelium but not endothelial progenitor cells are essential for tumor lymphangiogenesis and lymphatic metastasis. Cancer Res 2004;64: 3737-40.
-
(2004)
Cancer Res
, vol.64
, pp. 3737-3740
-
-
He, Y.1
Rajantie, I.2
Ilmonen, M.3
-
24
-
-
0037310399
-
Differential in vivo and in vitro expression of vascular endothelial growth factor (VEGF)-C and VEGF-D in tumors and its relationship to lymphatic metastasis in immunocompetent rats
-
Krishnan J, Kirkin V, Steffen A, et al. Differential in vivo and in vitro expression of vascular endothelial growth factor (VEGF)-C and VEGF-D In tumors and its relationship to lymphatic metastasis In immunocompetent rats. Cancer Res 2003;63:713-22.
-
(2003)
Cancer Res
, vol.63
, pp. 713-722
-
-
Krishnan, J.1
Kirkin, V.2
Steffen, A.3
-
25
-
-
0034192370
-
Establishment and characterization of a human lung cancer cell line NCl-H460-LNM35 with consistent lymphogenous metastasis via both subcutaneous and orthotopic propagation
-
Kozaki K, Miyaishi O, Tsukamoto T, Tatematsu Y, Hida T, Takahashi I. Establishment and characterization of a human lung cancer cell line NCl-H460-LNM35 with consistent lymphogenous metastasis via both subcutaneous and orthotopic propagation. Cancer Res 2000;60:2535-40.
-
(2000)
Cancer Res
, vol.60
, pp. 2535-2540
-
-
Kozaki, K.1
Miyaishi, O.2
Tsukamoto, T.3
Tatematsu, Y.4
Hida, T.5
Takahashi, I.6
-
26
-
-
0033870226
-
Influence of promoter and WHY post-transcriptional regulatory element on AAV-mediated transgene expression in the rat brain
-
Paterna JC. Moccetti T, Mura A, Feldon J, Bueler H. Influence of promoter and WHY post-transcriptional regulatory element on AAV-mediated transgene expression in the rat brain. Gene Ther 2000;7: 1304-11.
-
(2000)
Gene Ther
, vol.7
, pp. 1304-1311
-
-
Paterna, J.C.1
Moccetti, T.2
Mura, A.3
Feldon, J.4
Bueler, H.5
-
27
-
-
0025884056
-
Efficient selection for high-expression transfectants with a novel eukaryotic vector
-
Niwa H, Yamamura K, Miyazaki J, Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 1991;108:193-9.
-
(1991)
Gene
, vol.108
, pp. 193-199
-
-
Niwa, H.1
Yamamura, K.2
Miyazaki, J.3
-
28
-
-
17344371184
-
Adenovirus-mediated gene transfer to lower limb artery of patients with chronic critical leg ischemia
-
Laitinen M, Makinen K, Manninen H, et al. Adenovirus-mediated gene transfer to lower limb artery of patients with chronic critical leg ischemia. Hum Gene Ther 1998;9:1481-6.
-
(1998)
Hum Gene Ther
, vol.9
, pp. 1481-1486
-
-
Laitinen, M.1
Makinen, K.2
Manninen, H.3
-
29
-
-
0027301384
-
Apoptosis in torernifene-induced growth inhibition of human breast cancer cells in vivo and in vitro
-
Warri AM, Huovinen RL, Laine AM, Martikainen PM, Harkonen PL. Apoptosis in torernifene-induced growth inhibition of human breast cancer cells in vivo and in vitro, J Natl Cancer Inst 1993;85:1412-8.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 1412-1418
-
-
Warri, A.M.1
Huovinen, R.L.2
Laine, A.M.3
Martikainen, P.M.4
Harkonen, P.L.5
-
30
-
-
9144236286
-
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
-
Karkkainen MJ, Haiko P, Sainio K, et al. Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat Immunol 2004;5:74-80.
-
(2004)
Nat Immunol
, vol.5
, pp. 74-80
-
-
Karkkainen, M.J.1
Haiko, P.2
Sainio, K.3
-
31
-
-
0035375108
-
Mouse LYVE-1 is an endocytic receptor for hyaluronan in lymphatic endothelium
-
Prevo R, Banerji S, Ferguson DJ, Clasper S, Jackson DG. Mouse LYVE-1 is an endocytic receptor for hyaluronan in lymphatic endothelium, J Biol Chem 2001;276:19420-30.
-
(2001)
J Biol Chem
, vol.276
, pp. 19420-19430
-
-
Prevo, R.1
Banerji, S.2
Ferguson, D.J.3
Clasper, S.4
Jackson, D.G.5
-
32
-
-
0036087843
-
An invasion-independent pathway of blood-borne metastasis: A new murine mammary tumor model
-
Sugino T, Kusakabe T, Hoshi N, et al. An invasion-independent pathway of blood-borne metastasis: a new murine mammary tumor model. Am J Pathol 2002;160: 1973-80.
-
(2002)
Am J Pathol
, vol.160
, pp. 1973-1980
-
-
Sugino, T.1
Kusakabe, T.2
Hoshi, N.3
-
33
-
-
0033846016
-
Vascular endothelial growth factor receptor-3 in lymphanglogenesis in wound healing
-
Paavonen K, Puolakkainen P, Jussila L, Jahkola T, Alitalo K. Vascular endothelial growth factor receptor-3 in lymphanglogenesis in wound healing. Am J Pathol 2000;156:1499-304.
-
(2000)
Am J Pathol
, vol.156
, pp. 1499-2304
-
-
Paavonen, K.1
Puolakkainen, P.2
Jussila, L.3
Jahkola, T.4
Alitalo, K.5
-
34
-
-
10244235420
-
Prediction of the axillary lymph node status in mammary cancer on the basis of clinicopathological data and flow cytometry
-
Mattfeldt T, Kestler HA, Sinn HP. Prediction of the axillary lymph node status in mammary cancer on the basis of clinicopathological data and flow cytometry. Med Biol Eng Comput 2004;42:733-9.
-
(2004)
Med Biol Eng Comput
, vol.42
, pp. 733-739
-
-
Mattfeldt, T.1
Kestler, H.A.2
Sinn, H.P.3
|