Complement factor H variant Y402H is a major risk determinant for geographic atrophy and choroidal neovascularization in smokers and nonsmokers

Investigative Ophthalmology and Visual Science

Volumn 47, Issue 2, 2006, Pages 536-540

  Sepp, Tiina ^a   Khan, Jane C ^a   Thurlby, Deborah A ^a   Shahid, Humma ^a   Clayton, David G ^a   Moore, Anthony T ^b,c   Bird, Alan C ^b,c   Yates, John R W ^a,d   Bhattacharya, Shomi S ^b   Bishop, Paul N ^e   Black, Peter D ^f   Butt, Zahida A ^g   Chong, Victor N H ^h   Day, Nicholas E ⁱ   Edelsten, Clive ^j   Fitt, Alan W ^k   Flanagan, Declan W ^l   Glenn, Andrew M ^m   Harding, Simon ⁿ   Jakeman, Clifford M ^g   Jones, Colin D ^m   Lamb, Robert J ^o   Lotery, Andrew J ^p   Moffatt, Victor ⁿ   Moorman, Consuela M ^q   Peto, Tunde ^c   Pushpanathan, Rajadurai J ^g   Redmond, Elizabeth ^b   Rimmer, Timothy J ^k   more..

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c MOORFIELDS EYE HOSPITAL   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e MANCHESTER ROYAL EYE HOSPITAL   (United Kingdom)

^f JAMES PAGET UNIVERSITY HOSPITAL   (United Kingdom)

^g QUEEN ELIZABETH HOSPITAL   (United Kingdom)

^h KING S COLLEGE HOSPITAL   (United Kingdom)

ⁱ UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^j IPSWICH HOSPITAL   (United Kingdom)

^k PETERBOROUGH DISTRICT HOSPITAL   (United Kingdom)

^l ADDENBROOKE S HOSPITAL   (United Kingdom)

^m NORFOLK AND NORWICH UNIVERSITY HOSPITAL   (United Kingdom)

ⁿ ROYAL LIVERPOOL UNIVERSITY HOSPITAL   (United Kingdom)

^o WEST SUFFOLK HOSPITAL   (United Kingdom)

^p SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

^q STOKE MANDEVILLE HOSPITAL   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT FACTOR H; COMPLEMENT FACTOR H, HUMAN;

ADULT; AGED; ARTICLE; CHOROID GYRATE ATROPHY; CIGARETTE SMOKING; CONTROLLED STUDY; DISEASE COURSE; EYE EXAMINATION; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; GEOGRAPHY; HUMAN; LIFESTYLE MODIFICATION; MAJOR CLINICAL STUDY; MALE; OPHTHALMOSCOPY; PRIORITY JOURNAL; QUESTIONNAIRE; RETINA MACULA AGE RELATED DEGENERATION; RISK ASSESSMENT; SUBRETINAL NEOVASCULARIZATION; ALLELE; ATROPHY; CASE CONTROL STUDY; GENETICS; PATHOLOGY; PHOTORECEPTOR; PIGMENT EPITHELIUM; POLYMERASE CHAIN REACTION; RETINA MACULA DEGENERATION; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING;

AGED; AGED, 80 AND OVER; ALLELES; ATROPHY; CASE-CONTROL STUDIES; CHOROIDAL NEOVASCULARIZATION; COMPLEMENT FACTOR H; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; MACULAR DEGENERATION; MALE; PHOTORECEPTORS, VERTEBRATE; PIGMENT EPITHELIUM OF EYE; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SMOKING; VARIATION (GENETICS);

EID: 33644872864     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.05-1143     Document Type: Article

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