The Genetics of Adult-Onset Neuropsychiatric Disease: Complexities and Conundra?

Science

Volumn 302, Issue 5646, 2003, Pages 822-826

  Kennedy, James L ^a,b   Farrer, Lindsay A ^c,d   Andreasen, Nancy C ^e   Mayeux, Richard ^f   St George Hyslop, Peter ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^e UNIVERSITY OF NEW MEXICO   (United States)

^f Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H Sergievsky Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENES; HEALTH; NEUROLOGY;

ETIOLOGY;

DISEASES;

AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E; BRAIN DERIVED NEUROTROPHIC FACTOR; CATECHOL METHYLTRANSFERASE; NEU DIFFERENTIATION FACTOR; PRESENILIN 1; PRESENILIN 2; TAU PROTEIN;

ALZHEIMER DISEASE; AUTOSOMAL DOMINANT INHERITANCE; BIPOLAR DISORDER; DEGENERATIVE DISEASE; FRONTOTEMPORAL DEMENTIA; GENE LOCUS; GENETIC SUSCEPTIBILITY; HUMAN; NEUROPATHOLOGY; PARKINSON DISEASE; PENETRANCE; PRIORITY JOURNAL; REVIEW; SCHIZOPHRENIA;

ADULT; ALZHEIMER DISEASE; BIPOLAR DISORDER; CHROMOSOME MAPPING; DEMENTIA; GENETIC HETEROGENEITY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LINKAGE (GENETICS); MENTAL DISORDERS; MIDDLE AGED; MULTIFACTORIAL INHERITANCE; NEUREGULIN-1; NEURODEGENERATIVE DISEASES; PHENOTYPE; SCHIZOPHRENIA;

EID: 0242268946     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1092132     Document Type: Review

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56. Supported by grants from the Canadian Institutes of Health Research, Howard Hughes Foundation, Alzheimer Society of Ontario, Canadian Genetic Diseases Network, NIH (R01-AG09029, P30-AG95004, U01-AG17173, AG15473, AG07232, MH31593, MH40856, and MH43271), Philip Morris External Research Program, Banbury Fund, Taub Foundation, and Rockefeller Foundation.