메뉴 건너뛰기




Volumn 23, Issue 12, 2009, Pages 2238-2244

Variations in five genes and the severity of age-related macular degeneration: Results from the Muenster aging and retina study

Author keywords

Age related macular degeneration; ARMS2; C2; CFB; CFH; HtrA1; Severity

Indexed keywords

AGE RELATED MACULOPATHY SUSCEPTIBILITY; ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT COMPONENT C2; COMPLEMENT FACTOR H; EYE PROTEIN; HTRA SERINE PEPTIDASE 1; PEPTIDASE; UNCLASSIFIED DRUG;

EID: 72749123983     PISSN: 0950222X     EISSN: 14765454     Source Type: Journal    
DOI: 10.1038/eye.2008.426     Document Type: Article
Times cited : (35)

References (43)
  • 1
    • 33749440219 scopus 로고    scopus 로고
    • Age-related macular degeneration
    • De Jong PT. Age-related macular degeneration. N Engl J Med 2006; 355: 1474-1485.
    • (2006) N Engl J Med , vol.355 , pp. 1474-1485
    • De Jong, P.T.1
  • 3
    • 0028934221 scopus 로고
    • An international classification and grading system for age- related maculopathy and age-related macular degeneration
    • The International ARM Epidemiological Study Group
    • Bird AC, Bressler NM, Bressler SB, Chisholm IH, Coscas G, Davis MD et al. An international classification and grading system for age- related maculopathy and age-related macular degeneration. The International ARM Epidemiological Study Group. Surv Ophthalmol 1995; 39: 367-374.
    • (1995) Surv Ophthalmol , vol.39 , pp. 367-374
    • Bird, A.C.1    Bressler, N.M.2    Bressler, S.B.3    Chisholm, I.H.4    Coscas, G.5    Davis, M.D.6
  • 8
    • 21044453724 scopus 로고    scopus 로고
    • A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
    • Hageman GS, Anderson DH, Johnson LV, Hancox LS, Taiber AJ, Hardisty LI et al. A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci USA 2005; 102: 7227-7232.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 7227-7232
    • Hageman, G.S.1    Anderson, D.H.2    Johnson, L.V.3    Hancox, L.S.4    Taiber, A.J.5    Hardisty, L.I.6
  • 9
    • 20244388812 scopus 로고    scopus 로고
    • Complement factor H variant increases the risk of age-related macular degeneration
    • Haines JL, Hauser MA, Schmidt S, Scott WK, Olson LM, Gallins P et al. Complement factor H variant increases the risk of age-related macular degeneration. Science 2005; 308: 419-421.
    • (2005) Science , vol.308 , pp. 419-421
    • Haines, J.L.1    Hauser, M.A.2    Schmidt, S.3    Scott, W.K.4    Olson, L.M.5    Gallins, P.6
  • 10
    • 20244380171 scopus 로고    scopus 로고
    • Complement factor H polymorphism in age-related macular degeneration
    • Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, Haynes C et al. Complement factor H polymorphism in age-related macular degeneration. Science 2005; 308: 385-389.
    • (2005) Science , vol.308 , pp. 385-389
    • Klein, R.J.1    Zeiss, C.2    Chew, E.Y.3    Tsai, J.Y.4    Sackler, R.S.5    Haynes, C.6
  • 12
    • 27744462212 scopus 로고    scopus 로고
    • Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk
    • Rivera A, Fisher SA, Fritsche LG, Keilhauer CN, Lichtner P, Meitinger Tet al. Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk. Hum Mol Genet 2005; 14: 3227-3236.
    • (2005) Hum Mol Genet , vol.14 , pp. 3227-3236
    • Rivera, A.1    Fisher, S.A.2    Fritsche, L.G.3    Keilhauer, C.N.4    Lichtner, P.5    Meitinger, T.6
  • 13
    • 33646070308 scopus 로고    scopus 로고
    • Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration
    • Schmidt S, Hauser MA, Scott WK, Postel EA, Agarwal A, Gallins P et al. Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration. Am J Hum Genet 2006; 78: 852-864.
    • (2006) Am J Hum Genet , vol.78 , pp. 852-864
    • Schmidt, S.1    Hauser, M.A.2    Scott, W.K.3    Postel, E.A.4    Agarwal, A.5    Gallins, P.6
  • 15
    • 36049042661 scopus 로고    scopus 로고
    • A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration
    • Kanda A, Chen W, Othman M, Branham KE, Brooks M, Khanna R et al. A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration. Proc Natl Acad Sci USA 2007; 104: 16227-16232.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 16227-16232
    • Kanda, A.1    Chen, W.2    Othman, M.3    Branham, K.E.4    Brooks, M.5    Khanna, R.6
  • 16
    • 33751011889 scopus 로고    scopus 로고
    • HTRA1 promoter polymorphism in wet age-related macular degeneration
    • Dewan A, Liu M, Hartman S, Zhang SS, Liu DT, Zhao C et al. HTRA1 promoter polymorphism in wet age-related macular degeneration. Science 2006; 314: 989-992.
    • (2006) Science , vol.314 , pp. 989-992
    • Dewan, A.1    Liu, M.2    Hartman, S.3    Zhang, S.S.4    Liu, D.T.5    Zhao, C.6
  • 17
    • 33751004690 scopus 로고    scopus 로고
    • A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration
    • Yang Z, Camp NJ, Sun H, Tong Z, Gibbs D, Cameron DJ et al. A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration. Science 2006; 314: 992-993.
    • (2006) Science , vol.314 , pp. 992-993
    • Yang, Z.1    Camp, N.J.2    Sun, H.3    Tong, Z.4    Gibbs, D.5    Cameron, D.J.6
  • 18
    • 39149112776 scopus 로고    scopus 로고
    • Further mapping of 10q26 supports strong association of HTRA1 polymorphisms with age-related macular degeneration
    • Gibbs D, Yang Z, Constantine R, Ma X, Camp NJ, Yang X et al. Further mapping of 10q26 supports strong association of HTRA1 polymorphisms with age-related macular degeneration. Vision Res 2008; 48: 685-689.
    • (2008) Vision Res , vol.48 , pp. 685-689
    • Gibbs, D.1    Yang, Z.2    Constantine, R.3    Ma, X.4    Camp, N.J.5    Yang, X.6
  • 19
    • 34047270761 scopus 로고    scopus 로고
    • HTRA1 promoter polymorphism predisposes Japanese to age-related macular degeneration
    • Yoshida T, Dewan A, Zhang H, Sakamoto R, Okamoto H, Minami M et al. HTRA1 promoter polymorphism predisposes Japanese to age-related macular degeneration. Mol Vis 2007; 13: 545-548.
    • (2007) Mol Vis , vol.13 , pp. 545-548
    • Yoshida, T.1    Dewan, A.2    Zhang, H.3    Sakamoto, R.4    Okamoto, H.5    Minami, M.6
  • 20
    • 48249096770 scopus 로고    scopus 로고
    • C2 and CFB genes in age-related maculopathy and joint action with CFH and LOC387715 genes
    • Jakobsdottir J, Conley YP, Weeks DE, Ferrell RE, Gorin MB. C2 and CFB genes in age-related maculopathy and joint action with CFH and LOC387715 genes. PLoS ONE 2008; 3: e2199.
    • (2008) PLoS ONE , vol.3
    • Jakobsdottir, J.1    Conley, Y.P.2    Weeks, D.E.3    Ferrell, R.E.4    Gorin, M.B.5
  • 22
    • 33748309136 scopus 로고    scopus 로고
    • Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration
    • Maller J, George S, Purcell S, Fagerness J, Altshuler D, Daly MJ et al. Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration. Nat Genet 2006; 38: 1055-1059.
    • (2006) Nat Genet , vol.38 , pp. 1055-1059
    • Maller, J.1    George, S.2    Purcell, S.3    Fagerness, J.4    Altshuler, D.5    Daly, M.J.6
  • 23
    • 33645419787 scopus 로고    scopus 로고
    • Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration
    • AMD Genetics Clinical Study Group
    • Gold B, Merriam JE, Zernant J, Hancox LS, Taiber AJ, Gehrs K et al., AMD Genetics Clinical Study Group. Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration. Nat Genet 2006; 38: 458-462.
    • (2006) Nat Genet , Issue.38 , pp. 458-462
    • Gold, B.1    Merriam, J.E.2    Zernant, J.3    Hancox, L.S.4    Taiber, A.J.5    Gehrs, K.6
  • 24
    • 33746041795 scopus 로고    scopus 로고
    • Complement factor H polymorphism, complement activators, and risk of age-related macular degeneration
    • Despriet DD, Klaver CC,Witteman JC, Witteman JC, Bergen AA, Kardys I et al. Complement factor H polymorphism, complement activators, and risk of age-related macular degeneration. JAMA 2006; 296: 301-309.
    • (2006) JAMA , vol.296 , pp. 301-309
    • Despriet, D.D.1    Klaver, C.C.2    Witteman, J.C.3    Witteman, J.C.4    Bergen, A.A.5    Kardys, I.6
  • 25
    • 43549091327 scopus 로고    scopus 로고
    • Haplotypes in the complement factor H (CFH) gene: Associations with drusen and advanced age-related macular degeneration
    • Francis PJ, Schultz DW, Hamon S, Ott J, Weleber RG, Klein ML. Haplotypes in the complement factor H (CFH) gene: associations with drusen and advanced age-related macular degeneration. PLoS ONE 2007; 2: e1197.
    • (2007) PLoS ONE , vol.2
    • Francis, P.J.1    Schultz, D.W.2    Hamon, S.3    Ott, J.4    Weleber, R.G.5    Klein, M.L.6
  • 27
    • 38349178812 scopus 로고    scopus 로고
    • Phenotype analysis of patients with the risk variant LOC387715 (A69S) in age-related macular degeneration
    • Shuler Jr RK, Schmidt S, Gallins P, Hauser MA, Scott WK, Caldwell J et al. Phenotype analysis of patients with the risk variant LOC387715 (A69S) in age-related macular degeneration. Am J Ophthalmol 2008; 145: 303-307.
    • (2008) Am J Ophthalmol , vol.145 , pp. 303-307
    • Shuler Jr., R.K.1    Schmidt, S.2    Gallins, P.3    Hauser, M.A.4    Scott, W.K.5    Caldwell, J.6
  • 28
    • 39749170465 scopus 로고    scopus 로고
    • Peripheral reticular pigmentary change is associated with complement factor H polymorphism (Y402H) in age-related macular degeneration
    • Shuler Jr RK, Schmidt S, Gallins P, Hauser MA, Scott WK, Caldwell J et al. Peripheral reticular pigmentary change is associated with complement factor H polymorphism (Y402H) in age-related macular degeneration. Ophthalmology 2008; 115: 520-524.
    • (2008) Ophthalmology , vol.115 , pp. 520-524
    • Shuler Jr., R.K.1    Schmidt, S.2    Gallins, P.3    Hauser, M.A.4    Scott, W.K.5    Caldwell, J.6
  • 29
    • 33845806940 scopus 로고    scopus 로고
    • Population-based study of early age-related macular degeneration: Role of the complement factor H Y402H polymorphism in bilateral but not unilateral disease
    • Tedeschi-Blok N, Buckley J, Varma R, Triche TJ, Hinton DR. Population-based study of early age-related macular degeneration: role of the complement factor H Y402H polymorphism in bilateral but not unilateral disease. Ophthalmology 2007; 114: 99-103.
    • (2007) Ophthalmology , vol.114 , pp. 99-103
    • Tedeschi-Blok, N.1    Buckley, J.2    Varma, R.3    Triche, T.J.4    Hinton, D.R.5
  • 30
    • 34249675827 scopus 로고    scopus 로고
    • Two genetic pathways for age-related macular degeneration
    • Dewan A, Bracken MB, Hoh J. Two genetic pathways for age-related macular degeneration. Curr Opin Genet Dev 2007; 17: 228-233.
    • (2007) Curr Opin Genet Dev , vol.17 , pp. 228-233
    • Dewan, A.1    Bracken, M.B.2    Hoh, J.3
  • 32
    • 27744506525 scopus 로고    scopus 로고
    • Serum levels of macular carotenoids in relation to age-related maculopathy the Muenster Aging and Retina Study (MARS)
    • Dasch B, Fuhs A, Schmidt J, Behrens T, Meister A, Wellmann J et al. Serum levels of macular carotenoids in relation to age-related maculopathy The Muenster Aging and Retina Study (MARS). Graefes Arch Clin Exp Ophthalmol 2005; 243: 1028-1035.
    • (2005) Graefes Arch Clin Exp Ophthalmol , vol.243 , pp. 1028-1035
    • Dasch, B.1    Fuhs, A.2    Schmidt, J.3    Behrens, T.4    Meister, A.5    Wellmann, J.6
  • 33
    • 27744591080 scopus 로고    scopus 로고
    • [Association between classic cardiovascular risk factors and age-related maculopathy (ARM) Results of the baseline examination of the Munster Aging and Retina Study (MARS).]
    • Dasch B, Fuhs A, Meister A, Behrens T, Krause K, Pauleikhoff D et al. [Association between classic cardiovascular risk factors and age-related maculopathy (ARM) Results of the baseline examination of the Munster Aging and Retina Study (MARS).]. Ophthalmologe 2005; 102: 1057-1063.
    • (2005) Ophthalmologe , vol.102 , pp. 1057-1063
    • Dasch, B.1    Fuhs, A.2    Meister, A.3    Behrens, T.4    Krause, K.5    Pauleikhoff, D.6
  • 34
    • 27744450912 scopus 로고    scopus 로고
    • Inflammatory markers in age-related maculopathy: Cross-sectional analysis from the Muenster Aging and Retina Study
    • Dasch B, Fuhs A, Behrens T, Meister A, Wellmann J, Fobker M et al. Inflammatory markers in age-related maculopathy: cross-sectional analysis from the Muenster Aging and Retina Study. Arch Ophthalmol 2005; 123: 1501-1506.
    • (2005) Arch Ophthalmol , vol.123 , pp. 1501-1506
    • Dasch, B.1    Fuhs, A.2    Behrens, T.3    Meister, A.4    Wellmann, J.5    Fobker, M.6
  • 35
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005; 21: 263-265.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 36
    • 36749100977 scopus 로고    scopus 로고
    • PLEKHA1-LOC387715-HTRA1 polymorphisms and exudative age-related macular degeneration in the French population
    • Leveziel N, Souied EH, Richard F, Barbu V, Zourdani A, Morineau G et al. PLEKHA1-LOC387715-HTRA1 polymorphisms and exudative age-related macular degeneration in the French population. Mol Vis 2007; 13: 2153-2159.
    • (2007) Mol Vis , vol.13 , pp. 2153-2159
    • Leveziel, N.1    Souied, E.H.2    Richard, F.3    Barbu, V.4    Zourdani, A.5    Morineau, G.6
  • 37
    • 12244264435 scopus 로고    scopus 로고
    • Genetic Power Calculator: Design of linkage and association genetic mapping studies of complex traits
    • Purcell S, Cherny SS, Sham PC. Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics 2003; 19: 149-150.
    • (2003) Bioinformatics , vol.19 , pp. 149-150
    • Purcell, S.1    Cherny, S.S.2    Sham, P.C.3
  • 39
    • 58949096362 scopus 로고    scopus 로고
    • Complement factor H variant increases the risk for early age-related macular degeneration
    • Lin JM, Tsai YY, Wan L, Lin HJ, Tsai Y, Lee CC et al. Complement factor H variant increases the risk for early age-related macular degeneration. Retina 2008; 28: 1416-1420.
    • (2008) Retina , vol.28 , pp. 1416-1420
    • Lin, J.M.1    Tsai, Y.Y.2    Wan, L.3    Lin, H.J.4    Tsai, Y.5    Lee, C.C.6
  • 41
    • 33144459399 scopus 로고    scopus 로고
    • The role of inflammation in the pathogenesis of age-related macular degeneration
    • DOI 10.1016/j.survophthal.2005.12.001, PII S0039625705002067
    • Donoso LA, Kim D, Frost A, Callahan A, Hageman G. The role of inflammation in the pathogenesis of age-related macular degeneration. Surv Ophthalmol 2006; 51: 137-152. (Pubitemid 43269939)
    • (2006) Survey of Ophthalmology , vol.51 , Issue.2 , pp. 137-152
    • Donoso, L.A.1    Kim, D.2    Frost, A.3    Callahan, A.4    Hageman, G.5
  • 43
    • 33748752137 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of the association between complementary factor H Y402H polymorphisms and age-related macular degeneration
    • DOI 10.1093/hmg/ddl220
    • Thakkinstian A, Han P, McEvoy M, Smith W, Hoh J, Magnusson K et al. Systematic review and meta-analysis of the association between complement factor H Y402H polymorphisms and age-related macular degeneration. Hum Mol Genet 2006; 15: 2784-2790. (Pubitemid 44400405)
    • (2006) Human Molecular Genetics , vol.15 , Issue.18 , pp. 2784-2790
    • Thakkinstian, A.1    Han, P.2    McEvoy, M.3    Smith, W.4    Hoh, J.5    Magnusson, K.6    Zhang, K.7    Attia, J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.