Interpretation of genetic association studies: Markers with replicated highly significant odds ratios may be poor classifiers

PLoS Genetics

Volumn 5, Issue 2, 2009, Pages

  Jakobsdottir, Johanna ^a   Gorin, Michael B ^b   Conley, Yvette P ^a,c   Ferrell, Robert E ^a   Weeks, Daniel E ^a  

^a UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CARDIOVASCULAR RISK; CROHN DISEASE; ENTERITIS; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC MARKER; GENETIC RISK; GENETIC VARIABILITY; HUMAN; LOGISTIC REGRESSION ANALYSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; PROSTATE CANCER; RECEIVER OPERATING CHARACTERISTIC; RETINA MACULA AGE RELATED DEGENERATION; SINGLE NUCLEOTIDE POLYMORPHISM; GENETIC PREDISPOSITION; GENETIC SCREENING; GENETICS; MALE; METHODOLOGY; PROSTATE TUMOR; RETINA MACULA DEGENERATION; RISK; STATISTICAL MODEL;

DIABETES MELLITUS, TYPE 2; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INFLAMMATORY BOWEL DISEASES; LOGISTIC MODELS; MACULAR DEGENERATION; MALE; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSTATIC NEOPLASMS;

EID: 61449230785     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000337     Document Type: Article

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