A Common Polymorphism in the Complement Factor H Gene Is Associated With Increased Risk of Myocardial Infarction. The Rotterdam Study

Journal of the American College of Cardiology

Volumn 47, Issue 8, 2006, Pages 1568-1575

  Kardys, Isabella ^a   Klaver, Caroline C W ^a   Despriet, Dominiek D G ^a   Bergen, Arthur A B ^b,c   Uitterlinden, André G ^a   Hofman, Albert ^a   Oostra, Ben A ^a   Van Duijn, Cornelia M ^a   de Jong, Paulus T V M ^a,b,c   Witteman, Jacqueline C M ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CHOLESTEROL; COMPLEMENT FACTOR H; HISTIDINE; TYROSINE;

ADULT; AGE DISTRIBUTION; AGED; ALLELE; ARTICLE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONFIDENCE INTERVAL; DIABETES MELLITUS; DISEASE PREDISPOSITION; DNA POLYMORPHISM; FEMALE; FOLLOW UP; GENE FREQUENCY; GENOTYPE; HEART INFARCTION; HOMOZYGOTE; HUMAN; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; RISK ASSESSMENT; RISK FACTOR; SEX DIFFERENCE; SMOKING; BLOOD; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; INCIDENCE; MIDDLE AGED;

AGED; CHOLESTEROL; COMPLEMENT FACTOR H; DIABETES COMPLICATIONS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HISTIDINE; HOMOZYGOTE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; POLYMORPHISM, GENETIC; PROPORTIONAL HAZARDS MODELS; RISK FACTORS; SMOKING; TYROSINE;

EID: 33646588644     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2005.11.076     Document Type: Article

References (30)

1. Hansson G.K. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 352 (2005) 1685-1695
2. Oksjoki R., Kovanen P.T., and Pentikainen M.O. Role of complement activation in atherosclerosis. Curr Opin Lipidol 14 (2003) 477-482
3. Klein R.J., Zeiss C., Chew E.Y., et al. Complement factor H polymorphism in age-related macular degeneration. Science 308 (2005) 385-389
4. Haines J.L., Hauser M.A., Schmidt S., et al. Complement factor H variant increases the risk of age-related macular degeneration. Science 308 (2005) 419-421
5. Edwards A.O., Ritter III R., Abel K.J., Manning A., Panhuysen C., and Farrer L.A. Complement factor H polymorphism and age-related macular degeneration. Science 308 (2005) 421-424
6. Zareparsi S., Branham K.E., Li M., et al. Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration. Am J Hum Genet 77 (2005) 149-153
7. Hageman G.S., Anderson D.H., Johnson L.V., et al. A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci U S A 102 (2005) 7227-7232
8. Oksjoki R., Jarva H., Kovanen P.T., Laine P., Meri S., and Pentikainen M.O. Association between complement factor H and proteoglycans in early human coronary atherosclerotic lesions. implications for local regulation of complement activation. Arterioscler Thromb Vasc Biol 23 (2003) 630-636
9. Vingerling J.R., Dielemans I., Bots M.L., Hofman A., Grobbee D.E., and de Jong P.T. Age-related macular degeneration is associated with atherosclerosis. The Rotterdam study. Am J Epidemiol 142 (1995) 404-409
10. Rodriguez de Cordoba S., Esparza-Gordillo J., Goicoechea de Jorge E., Lopez-Trascasa M., and Sanchez-Corral P. The human complement factor H. functional roles, genetic variations and disease associations. Mol Immunol 41 (2004) 355-367
11. Giannakis E., Jokiranta T.S., Male D.A., et al. A common site within factor H SCR 7 responsible for binding heparin, C-reactive protein and streptococcal M protein. Eur J Immunol 33 (2003) 962-969
12. Hofman A., Grobbee D.E., de Jong P.T., and van den Ouweland F.A. Determinants of disease and disability in the elderly. the Rotterdam Elderly study. Eur J Epidemiol 7 (1991) 403-422
13. NCBI. Single Nucleotide Polymorphism. Available at: http://www.ncbi.nlm.nih.gov/SNP. Accessed March 6, 2006.
14. Applied Biosystems. Products and Services. Available at: http://store.appliedbiosystems.com. Accessed March 6, 2006.
15. WHO. Technical Rapport Series 727. Diabetes Mellitus (1985) Geneva, Switzerland
16. van Bemmel J.H., Kors J.A., and van Herpen G. Methodology of the modular ECG analysis system MEANS. Methods Inf Med 29 (1990) 346-353
17. Prineas R.J., Crow R.S., and Blackburn H. The Minnesota Code Manual of Electrocardiographic Findings (1982), John Wright PSG, Boston, MA
18. WHO. International Statistical Classification of Diseases and Related Health Problems, 10th revision (1992) Geneva, Switzerland
19. Fujinami T., Hirata H., Hayano J., Ohte N., Kohketsu M., and Hashimoto T. Coronary risk factors in angiographically defined patients with chest pain. Jpn J Med 29 (1990) 462-468
20. Seifert P.S., and Hansson G.K. Complement receptors and regulatory proteins in human atherosclerotic lesions. Arteriosclerosis 9 (1989) 802-811
21. Kaplan M.H., and Volanakis J.E. Interaction of C-reactive protein complexes with the complement system. I. Consumption of human complement associated with the reaction of C-reactive protein with pneumococcal C-polysaccharide and with the choline phosphatides, lecithin and sphingomyelin. J Immunol 112 (1974) 2135-2147
22. Mold C., Kingzette M., and Gewurz H. C-reactive protein inhibits pneumococcal activation of the alternative pathway by increasing the interaction between factor H and C3b. J Immunol 133 (1984) 882-885
23. Danesh J., Wheeler J.G., Hirschfield G.M., et al. C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. N Engl J Med 350 (2004) 1387-1397
24. Seddon J.M., Gensler G., Milton R.C., Klein M.L., and Rifai N. Association between C-reactive protein and age-related macular degeneration. JAMA 291 (2004) 704-710
25. Fearon D.T. Regulation by membrane sialic acid of beta1H-dependent decay-dissociation of amplification C3 convertase of the alternative complement pathway. Proc Natl Acad Sci U S A 75 (1978) 1971-1975
26. Zee RY, Diehl KA, Ridker PM. Complement factor H Y402H gene polymorphism, C-reactive protein, and risk of incident myocardial infarction, ischaemic stroke, and venous thromboembolism: a nested case-control study. Atherosclerosis 2006. In press.
27. Sheifer S.E., Gersh B.J., Yanez III N.D., Ades P.A., Burke G.L., and Manolio T.A. Prevalence, predisposing factors, and prognosis of clinically unrecognized myocardial infarction in the elderly. J Am Coll Cardiol 35 (2000) 119-126
28. Rothman K.J., and Greenland S. Modern Epidemiology. 2nd edition (1998), Lippincott Williams & Wilkins, Philadelphia, PA
29. Ziegler D. Type 2 diabetes as an inflammatory cardiovascular disorder. Curr Mol Med 5 (2005) 309-322
30. Ambrose J.A., and Barua R.S. The pathophysiology of cigarette smoking and cardiovascular disease. an update. J Am Coll Cardiol 43 (2004) 1731-1737