메뉴 건너뛰기




Volumn 49, Issue 4, 2008, Pages 1652-1659

Toll-like receptor polymorphisms and age-related macular degeneration

Author keywords

[No Author keywords available]

Indexed keywords

TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 10; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR;

EID: 45549091151     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.07-1378     Document Type: Article
Times cited : (76)

References (66)
  • 1
    • 11144354339 scopus 로고    scopus 로고
    • Prevalence of age- related macular degeneration in the United States
    • Friedman DS, O'Colmain BJ, Munoz B, et al. Prevalence of age- related macular degeneration in the United States. Arch Ophthalmol. 2004;122:564-572.
    • (2004) Arch Ophthalmol , vol.122 , pp. 564-572
    • Friedman, D.S.1    O'Colmain, B.J.2    Munoz, B.3
  • 3
    • 20244388812 scopus 로고    scopus 로고
    • Complement factor H variant increases the risk of age-related macular degeneration
    • Haines JL, Hauser MA, Schmidt S, et al. Complement factor H variant increases the risk of age-related macular degeneration. Science. 2005;308:419-421.
    • (2005) Science , vol.308 , pp. 419-421
    • Haines, J.L.1    Hauser, M.A.2    Schmidt, S.3
  • 4
    • 20244380171 scopus 로고    scopus 로고
    • Complement factor H polymorphism in age-related macular degeneration
    • Klein RJ, Zeiss C, Chew EY, et al. Complement factor H polymorphism in age-related macular degeneration. Science. 2005;308:385-389.
    • (2005) Science , vol.308 , pp. 385-389
    • Klein, R.J.1    Zeiss, C.2    Chew, E.Y.3
  • 6
    • 27744462212 scopus 로고    scopus 로고
    • Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk
    • Rivera A, Fisher SA, Fritsche LG, et al. Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk. Hum Mol Genet. 2005;14:3227-3236.
    • (2005) Hum Mol Genet , vol.14 , pp. 3227-3236
    • Rivera, A.1    Fisher, S.A.2    Fritsche, L.G.3
  • 7
    • 33645419787 scopus 로고    scopus 로고
    • Variation in factor B (BF) and complement component 2 (C2) genes is associated with age- related macular degeneration
    • Gold B, Merriam JE, Zernant J, et al. Variation in factor B (BF) and complement component 2 (C2) genes is associated with age- related macular degeneration. Nat Genet. 2006;38:458-462.
    • (2006) Nat Genet , vol.38 , pp. 458-462
    • Gold, B.1    Merriam, J.E.2    Zernant, J.3
  • 8
    • 20444471500 scopus 로고    scopus 로고
    • Association of HLA class I and class II polymorphisms with age-related macular degeneration
    • Goverdhan SV, Howell MW, Mullins RF, et al. Association of HLA class I and class II polymorphisms with age-related macular degeneration. Invest Ophthalmol Vis Sci. 2005;46:1726-1734.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 1726-1734
    • Goverdhan, S.V.1    Howell, M.W.2    Mullins, R.F.3
  • 9
    • 0032231956 scopus 로고    scopus 로고
    • Klaver CC, Kliffen M, van Duijn CM, et al. Genetic association of apolipoprotein E with age-related macular degeneration [published correction in Am J Hum Genet. 1998;63(4):1252]. Am J Hum Genet. 1998;63:200 -206.
    • Klaver CC, Kliffen M, van Duijn CM, et al. Genetic association of apolipoprotein E with age-related macular degeneration [published correction in Am J Hum Genet. 1998;63(4):1252]. Am J Hum Genet. 1998;63:200 -206.
  • 10
    • 0032014838 scopus 로고    scopus 로고
    • The epsilon4 allele of the apolipoprotein E gene as a potential protective factor for exudative age-related macular degeneration
    • Souied EH, Benlian P, Amouyel P, et al. The epsilon4 allele of the apolipoprotein E gene as a potential protective factor for exudative age-related macular degeneration. Am J Ophthalmol. 1998;125:353-359.
    • (1998) Am J Ophthalmol , vol.125 , pp. 353-359
    • Souied, E.H.1    Benlian, P.2    Amouyel, P.3
  • 11
    • 20544433415 scopus 로고    scopus 로고
    • Toll-like receptor 4 variant D299G is associated with susceptibility to age-related mac- ular degeneration
    • Zareparsi S, Buraczynska M, Branham KE, et al. Toll-like receptor 4 variant D299G is associated with susceptibility to age-related mac- ular degeneration. Hum Mol Genet. 2005;14:1449-1455.
    • (2005) Hum Mol Genet , vol.14 , pp. 1449-1455
    • Zareparsi, S.1    Buraczynska, M.2    Branham, K.E.3
  • 12
    • 33947315191 scopus 로고    scopus 로고
    • Molecular genetics of AMD and current animal models
    • Edwards AO, Malek G. Molecular genetics of AMD and current animal models. Angiogenesis 2007;10;119-132.
    • (2007) Angiogenesis , vol.10 , pp. 119-132
    • Edwards, A.O.1    Malek, G.2
  • 13
    • 34547764305 scopus 로고    scopus 로고
    • Complement C3 variant and the risk of age-related macular degeneration
    • Yates JR, Sepp T, Matharu BK, et al. Complement C3 variant and the risk of age-related macular degeneration. N Engl JMed. 2007;357:553-561.
    • (2007) N Engl JMed , vol.357 , pp. 553-561
    • Yates, J.R.1    Sepp, T.2    Matharu, B.K.3
  • 14
    • 33745712069 scopus 로고    scopus 로고
    • The role of complement in danger sensing and transmission
    • Kohl J. The role of complement in danger sensing and transmission. Immunol Res. 2006;34:157-176.
    • (2006) Immunol Res , vol.34 , pp. 157-176
    • Kohl, J.1
  • 15
    • 33846245059 scopus 로고    scopus 로고
    • Translational Mini-Review Series on Toll-like Receptors: Networks regulated by toll-like receptors mediate innate and adaptive immunity
    • Parker LC, Prince LR, Sabroe I. Translational Mini-Review Series on Toll-like Receptors: networks regulated by toll-like receptors mediate innate and adaptive immunity. Clin ExpImmunol. 2007;147:199 -207.
    • (2007) Clin ExpImmunol , vol.147 , pp. 199-207
    • Parker, L.C.1    Prince, L.R.2    Sabroe, I.3
  • 16
    • 0030831210 scopus 로고    scopus 로고
    • A human homo- logue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. A human homo- logue of the Drosophila Toll protein signals activation of adaptive immunity. Nature. 1997;388:394 -397.
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway Jr, C.A.3
  • 17
    • 0032509295 scopus 로고    scopus 로고
    • Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
    • Poltorak A, He X, Smirnova I, et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science. 1998;282:2085-2088.
    • (1998) Science , vol.282 , pp. 2085-2088
    • Poltorak, A.1    He, X.2    Smirnova, I.3
  • 18
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
    • Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature. 2001;413:732-738.
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 19
    • 1542317578 scopus 로고    scopus 로고
    • Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
    • Heil F, Hemmi H, Hochrein H, et al. Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science. 2004;303:1526-1529.
    • (2004) Science , vol.303 , pp. 1526-1529
    • Heil, F.1    Hemmi, H.2    Hochrein, H.3
  • 20
    • 1542317550 scopus 로고    scopus 로고
    • Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
    • Diebold SS, Kaisho T, Hemmi H, Akira S, Reise Sousa C. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science. 2004;303:1529 -1531.
    • (2004) Science , vol.303 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3    Akira, S.4    Reise Sousa, C.5
  • 21
    • 3843049059 scopus 로고    scopus 로고
    • Toll-like receptor 4 (TLR4) of retinal pigment epithelial cells participates in transmembrane signaling in response to photoreceptor outer segments
    • Kindzelskii AL, Elner VM, Elner SG, Yang D, Hughes BA, Petty HR. Toll-like receptor 4 (TLR4) of retinal pigment epithelial cells participates in transmembrane signaling in response to photoreceptor outer segments. J Gen Physiol. 2004;124:139-149.
    • (2004) J Gen Physiol , vol.124 , pp. 139-149
    • Kindzelskii, A.L.1    Elner, V.M.2    Elner, S.G.3    Yang, D.4    Hughes, B.A.5    Petty, H.R.6
  • 22
    • 0032468842 scopus 로고    scopus 로고
    • Age-related macular degeneration: Clinical features in a large family and linkage to chromosome 1q
    • Klein ML, Schultz DW, Edwards A, et al. Age-related macular degeneration: clinical features in a large family and linkage to chromosome 1q. Arch Ophthalmol. 1998;116:1082-1088.
    • (1998) Arch Ophthalmol , vol.116 , pp. 1082-1088
    • Klein, M.L.1    Schultz, D.W.2    Edwards, A.3
  • 23
    • 0041886495 scopus 로고    scopus 로고
    • Age-related macular degeneration: A genome scan in extended families
    • Majewski J, Schultz DW, Weleber RG, et al. Age-related macular degeneration: a genome scan in extended families. Am J Hum Genet. 2003;73:540 -550.
    • (2003) Am J Hum Genet , vol.73 , pp. 540-550
    • Majewski, J.1    Schultz, D.W.2    Weleber, R.G.3
  • 24
    • 34548072024 scopus 로고    scopus 로고
    • Genetics of pigment changes and geographic atrophy
    • Thompson CL, Jun G, Klein BE, et al. Genetics of pigment changes and geographic atrophy. Invest Ophthalmol Vis Sci. 2007;48:3005-3013.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 3005-3013
    • Thompson, C.L.1    Jun, G.2    Klein, B.E.3
  • 25
    • 9144228044 scopus 로고    scopus 로고
    • Dissection of genomewide-scan data in extended families reveals a major locus and oligogenic susceptibility for age-related macular degeneration
    • Iyengar SK, Song D, Klein BE, et al. Dissection of genomewide-scan data in extended families reveals a major locus and oligogenic susceptibility for age-related macular degeneration. Am J Hum Genet. 2004;74:20 -39.
    • (2004) Am J Hum Genet , vol.74 , pp. 20-39
    • Iyengar, S.K.1    Song, D.2    Klein, B.E.3
  • 26
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005;21:263-265.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 27
    • 0036155283 scopus 로고    scopus 로고
    • Score tests for association between traits and haplotypes when linkage phase is ambiguous
    • Schaid DJ, Rowland CM, Tines DE, Jacobson RM, Poland GA. Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am J Hum Genet. 2002;70:425-434.
    • (2002) Am J Hum Genet , vol.70 , pp. 425-434
    • Schaid, D.J.1    Rowland, C.M.2    Tines, D.E.3    Jacobson, R.M.4    Poland, G.A.5
  • 28
    • 0344410771 scopus 로고    scopus 로고
    • Inference on haplotype effects in case- control studies using unphased genotype data
    • Epstein MP, Satten GA. Inference on haplotype effects in case- control studies using unphased genotype data. Am JHum Genet. 2003;73:1316-1329.
    • (2003) Am JHum Genet , vol.73 , pp. 1316-1329
    • Epstein, M.P.1    Satten, G.A.2
  • 29
    • 84869264483 scopus 로고    scopus 로고
    • Duncan RD, Epstein MP, Satten GA. Case-control haplotype inference CHAPLIN, version 1.2, September 2006
    • Duncan RD, Epstein MP, Satten GA. Case-control haplotype inference (CHAPLIN), version 1.2, September 2006, http://www.genetics.emory.edu/labs/ epstein/software/chaplin/index.html.
  • 30
    • 33746041795 scopus 로고    scopus 로고
    • Complement factor H polymorphism, complement activators, and risk of age-related macular degeneration
    • Despriet DD, Klaver CC, Witteman JC, et al. Complement factor H polymorphism, complement activators, and risk of age-related macular degeneration. JAMA. 2006;296:301-309.
    • (2006) JAMA , vol.296 , pp. 301-309
    • Despriet, D.D.1    Klaver, C.C.2    Witteman, J.C.3
  • 31
    • 0037184995 scopus 로고    scopus 로고
    • Pattern recognition receptors: Doubling up for the innate immune response
    • Gordon S. Pattern recognition receptors: doubling up for the innate immune response. Cell. 2002;111:927-930.
    • (2002) Cell , vol.111 , pp. 927-930
    • Gordon, S.1
  • 33
    • 27744444832 scopus 로고    scopus 로고
    • RNA-associated autoantigens activate B cells by combined B cell antigen receptor/toll-like receptor 7 engagement
    • Lau CM, Broughton C, Tabor AS, et al. RNA-associated autoantigens activate B cells by combined B cell antigen receptor/toll-like receptor 7 engagement. J Exp Med. 2005;202:1171-1177.
    • (2005) J Exp Med , vol.202 , pp. 1171-1177
    • Lau, C.M.1    Broughton, C.2    Tabor, A.S.3
  • 34
    • 33751564664 scopus 로고    scopus 로고
    • TLR2/TLR4-independent neutrophil activation and recruitment upon endo-cytosis of nucleosomes reveals a new pathway of innate immunity in systemic lupus erythematosus
    • Ronnefarth VM, Erbacher AI, Lamkemeyer T, et al. TLR2/TLR4-independent neutrophil activation and recruitment upon endo-cytosis of nucleosomes reveals a new pathway of innate immunity in systemic lupus erythematosus. J Immunol. 2006;177:7740-7749.
    • (2006) J Immunol , vol.177 , pp. 7740-7749
    • Ronnefarth, V.M.1    Erbacher, A.I.2    Lamkemeyer, T.3
  • 35
    • 0035877013 scopus 로고    scopus 로고
    • An essential role of the NF-kappa B/Toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells
    • Li M, Carpio DF, Zheng Y, et al. An essential role of the NF-kappa B/Toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells. J Immunol. 2001; 166:7128-7135.
    • (2001) J Immunol , vol.166 , pp. 7128-7135
    • Li, M.1    Carpio, D.F.2    Zheng, Y.3
  • 37
    • 33646477966 scopus 로고    scopus 로고
    • Endogenous adjuvant activity of the RNA components of lupus autoantigens Sm/RNP and Ro 60
    • Kelly KM, Zhuang H, Nacionales DC, et al. "Endogenous adjuvant" activity of the RNA components of lupus autoantigens Sm/RNP and Ro 60. Arthritis Rheum. 2006;54:1557-1567.
    • (2006) Arthritis Rheum , vol.54 , pp. 1557-1567
    • Kelly, K.M.1    Zhuang, H.2    Nacionales, D.C.3
  • 38
    • 23344431978 scopus 로고    scopus 로고
    • The molecular structure of the toll-like receptor 3 ligand-binding domain
    • Bell JK, Botos I, Hall PR, et al. The molecular structure of the toll-like receptor 3 ligand-binding domain. Proc Natl Acad Sci USA. 2005;102:10976-10980.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 10976-10980
    • Bell, J.K.1    Botos, I.2    Hall, P.R.3
  • 39
    • 33744965385 scopus 로고    scopus 로고
    • Structural and functional analyses of the human toll-like receptor 3. Role of glycosylation
    • Sun J, Duffy KE, Ranjith-Kumar CT, et al. Structural and functional analyses of the human toll-like receptor 3. Role of glycosylation. J Biol Chem. 2006;281:11144-11151.
    • (2006) J Biol Chem , vol.281 , pp. 11144-11151
    • Sun, J.1    Duffy, K.E.2    Ranjith-Kumar, C.T.3
  • 40
    • 23044445303 scopus 로고    scopus 로고
    • Crystal structure of human toll-like receptor 3 (TLR3) ectodomain
    • Choe J, Kelker MS, Wilson IA. Crystal structure of human toll-like receptor 3 (TLR3) ectodomain. Science. 2005;309:581-585.
    • (2005) Science , vol.309 , pp. 581-585
    • Choe, J.1    Kelker, M.S.2    Wilson, I.A.3
  • 41
    • 34147116078 scopus 로고    scopus 로고
    • Biochemical and functional analyses of the human toll-like receptor 3 ectodomain
    • Ranjith-Kumar CT, Miller W, Xiong J, et al. Biochemical and functional analyses of the human toll-like receptor 3 ectodomain. J Biol Chem. 2007;282:7668-7688.
    • (2007) J Biol Chem , vol.282 , pp. 7668-7688
    • Ranjith-Kumar, C.T.1    Miller, W.2    Xiong, J.3
  • 42
    • 31344476404 scopus 로고    scopus 로고
    • Recognition of double- stranded RNA by human toll-like receptor 3 and downstream receptor signaling requires multimerization and an acidic pH
    • de Bouteiller O, Merck E, Hasan UA, et al. Recognition of double- stranded RNA by human toll-like receptor 3 and downstream receptor signaling requires multimerization and an acidic pH. J Biol Chem. 2005;280:38133-38145.
    • (2005) J Biol Chem , vol.280 , pp. 38133-38145
    • de Bouteiller, O.1    Merck, E.2    Hasan, U.A.3
  • 43
    • 3242670505 scopus 로고    scopus 로고
    • Innate immunity in the retina: Toll-like receptor (TLR) signaling in human retinal pigment epithelial cells
    • Kumar MV, Nagineni CN, Chin MS, Hooks JJ, Detrick B. Innate immunity in the retina: toll-like receptor (TLR) signaling in human retinal pigment epithelial cells. J Neuroimmunol. 2004;153:7-15.
    • (2004) J Neuroimmunol , vol.153 , pp. 7-15
    • Kumar, M.V.1    Nagineni, C.N.2    Chin, M.S.3    Hooks, J.J.4    Detrick, B.5
  • 44
    • 33644798080 scopus 로고    scopus 로고
    • TLR4 mediates human retinal pigment epithelial endotoxin binding and cytokine expression
    • Elner SG, Petty HR, Elner VM, et al. TLR4 mediates human retinal pigment epithelial endotoxin binding and cytokine expression. Invest Ophthalmol Vis Sci. 2005;46:4627- 4633.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 4627-4633
    • Elner, S.G.1    Petty, H.R.2    Elner, V.M.3
  • 45
    • 0034832029 scopus 로고    scopus 로고
    • An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration
    • Hageman GS, Luthert PJ, Victor Chong NH, Johnson LV, Anderson DH, Mullins RF. An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration. Prog Retin Eye Res. 2001;20:705-732.
    • (2001) Prog Retin Eye Res , vol.20 , pp. 705-732
    • Hageman, G.S.1    Luthert, P.J.2    Victor Chong, N.H.3    Johnson, L.V.4    Anderson, D.H.5    Mullins, R.F.6
  • 46
    • 26444552110 scopus 로고    scopus 로고
    • Virus infection switches TLR-3-positive human neurons to become strong producers of beta interferon
    • Prehaud C, Megret F, Lafage M, Lafon M. Virus infection switches TLR-3-positive human neurons to become strong producers of beta interferon. J Virol. 2005;79:12893-12904.
    • (2005) J Virol , vol.79 , pp. 12893-12904
    • Prehaud, C.1    Megret, F.2    Lafage, M.3    Lafon, M.4
  • 48
    • 0042069977 scopus 로고    scopus 로고
    • The critical role of ocular-infiltrating macrophages in the development of choroidal neovascularization
    • Tsutsumi C, Sonoda KH, Egashira K, et al. The critical role of ocular-infiltrating macrophages in the development of choroidal neovascularization. J Leukoc Biol. 2003;74:25-32.
    • (2003) J Leukoc Biol , vol.74 , pp. 25-32
    • Tsutsumi, C.1    Sonoda, K.H.2    Egashira, K.3
  • 49
    • 0344676389 scopus 로고    scopus 로고
    • An animal model of age- related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice
    • Ambati J, Anand A, Fernandez S, et al. An animal model of age- related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice. Nat Med. 2003;9:1390-1397.
    • (2003) Nat Med , vol.9 , pp. 1390-1397
    • Ambati, J.1    Anand, A.2    Fernandez, S.3
  • 50
    • 14744279701 scopus 로고    scopus 로고
    • Choroidal dendritic cells require activation to present antigen and resident choroidal macrophages potentiate this response
    • Forrester JV, Lumsden L, Duncan L, Dick AD. Choroidal dendritic cells require activation to present antigen and resident choroidal macrophages potentiate this response. Br J Ophthalmol. 2005;89:369-377.
    • (2005) Br J Ophthalmol , vol.89 , pp. 369-377
    • Forrester, J.V.1    Lumsden, L.2    Duncan, L.3    Dick, A.D.4
  • 51
    • 33845497259 scopus 로고    scopus 로고
    • Interferon-beta and adhesion molecules (E-selectin and s-intracellular adhesion molecule-1) are detected in sera from patients with retinal vasculitis and are induced in retinal vascular endothelial cells by Toll-like receptor 3 signalling
    • Lee MT, Hooper LC, Kump L, et al. Interferon-beta and adhesion molecules (E-selectin and s-intracellular adhesion molecule-1) are detected in sera from patients with retinal vasculitis and are induced in retinal vascular endothelial cells by Toll-like receptor 3 signalling. Clin Exp Immunol. 2007;147:71-80.
    • (2007) Clin Exp Immunol , vol.147 , pp. 71-80
    • Lee, M.T.1    Hooper, L.C.2    Kump, L.3
  • 52
    • 33845236216 scopus 로고    scopus 로고
    • Ligands to nucleic acid- specific toll-like receptors and the onset of lupus nephritis
    • Pawar RD, Patole PS, Ellwart A, et al. Ligands to nucleic acid- specific toll-like receptors and the onset of lupus nephritis. J Am Soc Nephrol. 2006;17:3365-3373.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 3365-3373
    • Pawar, R.D.1    Patole, P.S.2    Ellwart, A.3
  • 53
    • 0028201732 scopus 로고
    • Tolerance, danger, and the extended family
    • Matzinger P. Tolerance, danger, and the extended family. Annu Rev Immunol. 1994;12:991-1045.
    • (1994) Annu Rev Immunol , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 54
    • 0023199438 scopus 로고
    • Detection of specific extracellular matrix molecules in drusen, Bruch's membrane, and ciliary body
    • Newsome DA, Hewitt AT, Huh W, Robey PG, Hassell JR. Detection of specific extracellular matrix molecules in drusen, Bruch's membrane, and ciliary body. Am J Ophthalmol. 1987; 104:373-381.
    • (1987) Am J Ophthalmol , vol.104 , pp. 373-381
    • Newsome, D.A.1    Hewitt, A.T.2    Huh, W.3    Robey, P.G.4    Hassell, J.R.5
  • 56
    • 0034012166 scopus 로고    scopus 로고
    • Mullins RF, Russell SR, Anderson DH, Hageman GS. Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease. FASEB J. 2000;14:835- 846.
    • Mullins RF, Russell SR, Anderson DH, Hageman GS. Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease. FASEB J. 2000;14:835- 846.
  • 57
    • 0035699547 scopus 로고    scopus 로고
    • Complement activation and inflammatory processes in drusen formation and age related macular degeneration
    • Johnson LV, Leitner WP, Staples MK, Anderson DH. Complement activation and inflammatory processes in drusen formation and age related macular degeneration. Exp Eye Res. 2001; 73:887-896.
    • (2001) Exp Eye Res , vol.73 , pp. 887-896
    • Johnson, L.V.1    Leitner, W.P.2    Staples, M.K.3    Anderson, D.H.4
  • 58
    • 11144258543 scopus 로고    scopus 로고
    • Drusen proteome analysis: An approach to the etiology of age-related macular degeneration
    • Crabb JW, Miyagi M, Gu X, et al. Drusen proteome analysis: an approach to the etiology of age-related macular degeneration. Proc Natl Acad Sci USA. 2002;99:14682-14687.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 14682-14687
    • Crabb, J.W.1    Miyagi, M.2    Gu, X.3
  • 59
    • 0142242222 scopus 로고    scopus 로고
    • Carboxxyethylpyrrole protein adducts and autoantibodies' biomarkers for age-related macular degeneration
    • Gu X, Meer SG, Miyagi M, et al. Carboxxyethylpyrrole protein adducts and autoantibodies' biomarkers for age-related macular degeneration. J Biol Chem. 2003;278:42027-42035.
    • (2003) J Biol Chem , vol.278 , pp. 42027-42035
    • Gu, X.1    Meer, S.G.2    Miyagi, M.3
  • 60
    • 0034954060 scopus 로고    scopus 로고
    • Structure and composition of drusen associated with glomerulonephritis: Implications for the role of complement activation in drusen biogenesis
    • Mullins RF, Aptsiauri N, Hageman GS. Structure and composition of drusen associated with glomerulonephritis: implications for the role of complement activation in drusen biogenesis. Eye. 2001;15: 390-395.
    • (2001) Eye , vol.15 , pp. 390-395
    • Mullins, R.F.1    Aptsiauri, N.2    Hageman, G.S.3
  • 62
    • 0025086052 scopus 로고
    • Macrophages related to Bruch's membrane in age-related macular degeneration
    • Kilingsworth MC, Sarks JP, Sarks SH. Macrophages related to Bruch's membrane in age-related macular degeneration. Eye. 1990;4:613-621.
    • (1990) Eye , vol.4 , pp. 613-621
    • Kilingsworth, M.C.1    Sarks, J.P.2    Sarks, S.H.3
  • 63
    • 33750576993 scopus 로고    scopus 로고
    • Role of toll-like receptor signalling in Abeta uptake and clearance
    • Tahara K, Kim HD, Jin JJ, Maxwell JA Li L, Fukuchi K. Role of toll-like receptor signalling in Abeta uptake and clearance. Brain. 2006;129:3006-3019.
    • (2006) Brain , vol.129 , pp. 3006-3019
    • Tahara, K.1    Kim, H.D.2    Jin, J.J.3    Maxwell, J.A.4    Li, L.5    Fukuchi, K.6
  • 64
    • 33751243644 scopus 로고    scopus 로고
    • Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid
    • Johnson PT, Betts KE, RRadeke MJ, Hageman GS, Anderson DH Johnson LV. Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid. Proc Natl Acad Sci USA. 2006;103:17456-17461.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 17456-17461
    • Johnson, P.T.1    Betts, K.E.2    RRadeke, M.J.3    Hageman, G.S.4    Anderson, D.H.5    Johnson, L.V.6
  • 65
    • 0036741098 scopus 로고    scopus 로고
    • A role for local inflammation in the formation of drusen in the aging eye
    • Anderson DH, Mullins RF, Hageman GS, Johnson LV. A role for local inflammation in the formation of drusen in the aging eye. Am J Ophthalmol. 2002;134:411-431.
    • (2002) Am J Ophthalmol , vol.134 , pp. 411-431
    • Anderson, D.H.1    Mullins, R.F.2    Hageman, G.S.3    Johnson, L.V.4
  • 66
    • 33748296239 scopus 로고    scopus 로고
    • Immunoprivileged status of the liver is controlled by toll-like receptor 3 signaling
    • Lang KS, Georgiev P, Recher M' et al. Immunoprivileged status of the liver is controlled by toll-like receptor 3 signaling. JClin Invest. 2006;116:2456-2463.
    • (2006) JClin Invest , vol.116 , pp. 2456-2463
    • Lang, K.S.1    Georgiev, P.2    M', R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.