-
1
-
-
70350504453
-
The DNA-damage response in human biology and disease
-
Jackson SP, Bartek J. The DNA-damage response in human biology and disease. Nature 2009; 461:1071-8.
-
(2009)
Nature
, vol.461
, pp. 1071-1078
-
-
Jackson, S.P.1
Bartek, J.2
-
2
-
-
78649336706
-
The DNA damage response: Making it safe to play with knives
-
Ciccia A, Elledge SJ. The DNA damage response: making it safe to play with knives. Mol Cell 2010; 40:179-204.
-
(2010)
Mol Cell
, vol.40
, pp. 179-204
-
-
Ciccia, A.1
Elledge, S.J.2
-
3
-
-
33847737716
-
DNA damage checkpoints: From initiation to recovery or adaptation
-
DOI 10.1016/j.ceb.2007.02.009, PII S0955067407000233
-
Bartek J, Lukas J. DNA damage checkpoints: from initiation to recovery or adaptation. Curr Opin Cell Biol 2007; 19:238-45. (Pubitemid 46386406)
-
(2007)
Current Opinion in Cell Biology
, vol.19
, Issue.2
, pp. 238-245
-
-
Bartek, J.1
Lukas, J.2
-
4
-
-
51349144633
-
Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery
-
Macurek L, Lindqvist A, Lim D, Lampson MA, Klompmaker R, Freire R, et al. Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery. Nature 2008; 455:119-23.
-
(2008)
Nature
, vol.455
, pp. 119-123
-
-
Macurek, L.1
Lindqvist, A.2
Lim, D.3
Lampson, M.A.4
Klompmaker, R.5
Freire, R.6
-
6
-
-
34548253635
-
Checkpoint adaptation in human cells
-
Syljuasen RG. Checkpoint adaptation in human cells. Oncogene 2007; 26:5833-9.
-
(2007)
Oncogene
, vol.26
, pp. 5833-5839
-
-
Syljuasen, R.G.1
-
7
-
-
34249947699
-
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
-
DOI 10.1126/science.1140321
-
Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER, III, Hurov KE, Luo J, et al. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 2007; 316:1160-6. (Pubitemid 46877472)
-
(2007)
Science
, vol.316
, Issue.5828
, pp. 1160-1166
-
-
Matsuoka, S.1
Ballif, B.A.2
Smogorzewska, A.3
McDonald III, E.R.4
Hurov, K.E.5
Luo, J.6
Bakalarski, C.E.7
Zhao, Z.8
Solimini, N.9
Lerenthal, Y.10
Shiloh, Y.11
Gygi, S.P.12
Elledge, S.J.13
-
8
-
-
77953148666
-
Site-specific phosphorylation dynamics of the nuclear proteome during the DNA damage response
-
Bennetzen MV, Larsen DH, Bunkenborg J, Bartek J, Lukas J, Andersen JS. Site-specific phosphorylation dynamics of the nuclear proteome during the DNA damage response. Mol Cell Proteomics 2010; 9:1314-23.
-
(2010)
Mol Cell Proteomics
, vol.9
, pp. 1314-1323
-
-
Bennetzen, M.V.1
Larsen, D.H.2
Bunkenborg, J.3
Bartek, J.4
Lukas, J.5
Andersen, J.S.6
-
9
-
-
78649938817
-
ATM-dependent and -independent dynamics of the nuclear phosphoproteome after DNA damage
-
Bensimon A, Schmidt A, Ziv Y, Elkon R, Wang SY, Chen DJ, et al. ATM-dependent and -independent dynamics of the nuclear phosphoproteome after DNA damage. Sci Signal 2010; 3:3.
-
(2010)
Sci Signal
, vol.3
, pp. 3
-
-
Bensimon, A.1
Schmidt, A.2
Ziv, Y.3
Elkon, R.4
Wang, S.Y.5
Chen, D.J.6
-
10
-
-
1842614272
-
Recovery from DNA damage checkpoint arrest by PP1-mediated inhibition of Chk1
-
DOI 10.1038/sj.emboj.7600105
-
den Elzen NR, O'Connell MJ. Recovery from DNA damage checkpoint arrest by PP1-mediated inhibition of Chk1. EMBO J 2004; 23:908-18. (Pubitemid 38418757)
-
(2004)
EMBO Journal
, vol.23
, Issue.4
, pp. 908-918
-
-
Den, E.N.R.1
O'Connell, M.J.2
-
11
-
-
70349122544
-
Phosphatase inhibition and cell survival after DNA damage induced by radiation
-
Hamilton J, Grawenda AM, Bernhard EJ. Phosphatase inhibition and cell survival after DNA damage induced by radiation. Cancer Biol Ther 2009; 8:1577-86.
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 1577-1586
-
-
Hamilton, J.1
Grawenda, A.M.2
Bernhard, E.J.3
-
12
-
-
78049342712
-
The protein phosphatase 1 regulator PNUTS is a new component of the DNA damage response
-
Landsverk HB, Mora-Bermudez F, Landsverk OJ, Hasvold G, Naderi S, Bakke O, et al. The protein phosphatase 1 regulator PNUTS is a new component of the DNA damage response. EMBO Rep 2010; 11:868-75.
-
(2010)
EMBO Rep
, vol.11
, pp. 868-875
-
-
Landsverk, H.B.1
Mora-Bermudez, F.2
Landsverk, O.J.3
Hasvold, G.4
Naderi, S.5
Bakke, O.6
-
13
-
-
77649178662
-
Repo-man controls a protein phosphatase 1-dependent threshold for DNA damage checkpoint activation
-
Peng A, Lewellyn AL, Schiemann WP, Maller JL. Repo-man controls a protein phosphatase 1-dependent threshold for DNA damage checkpoint activation. Curr Biol 2010; 20:387-96.
-
(2010)
Curr Biol
, vol.20
, pp. 387-396
-
-
Peng, A.1
Lewellyn, A.L.2
Schiemann, W.P.3
Maller, J.L.4
-
14
-
-
42149114544
-
A novel ATM-dependent pathway regulates protein phosphatase 1 in response to DNA damage
-
DOI 10.1128/MCB.01711-07
-
Tang X, Hui ZG, Cui XL, Garg R, Kastan MB, Xu B. A novel ATM-dependent pathway regulates protein phosphatase 1 in response to DNA damage. Mol Cell Biol 2008; 28:2559-66. (Pubitemid 351542357)
-
(2008)
Molecular and Cellular Biology
, vol.28
, Issue.8
, pp. 2559-2566
-
-
Tang, X.1
Hui, Z.-G.2
Cui, X.-L.3
Garg, R.4
Kastan, M.B.5
Xu, B.6
-
15
-
-
33750618926
-
Mitotic phosphatases: No longer silent partners
-
DOI 10.1016/j.ceb.2006.09.001, PII S0955067406001463
-
Trinkle-Mulcahy L, Lamond AI. Mitotic phosphatases: no longer silent partners. Curr Opin Cell Biol 2006; 18:623-31. (Pubitemid 44692470)
-
(2006)
Current Opinion in Cell Biology
, vol.18
, Issue.6
, pp. 623-631
-
-
Trinkle-Mulcahy, L.1
Lamond, A.I.2
-
16
-
-
70349333819
-
Mitotic phosphatases: From entry guards to exit guides
-
Bollen M, Gerlich DW, Lesage B. Mitotic phosphatases: from entry guards to exit guides. Trends Cell Biol 2009; 19:531-41.
-
(2009)
Trends Cell Biol
, vol.19
, pp. 531-541
-
-
Bollen, M.1
Gerlich, D.W.2
Lesage, B.3
-
18
-
-
61649127812
-
From promiscuity to precision: Protein phosphatases get a makeover
-
Virshup DM, Shenolikar S. From promiscuity to precision: protein phosphatases get a makeover. Mol Cell 2009; 33:537-45.
-
(2009)
Mol Cell
, vol.33
, pp. 537-545
-
-
Virshup, D.M.1
Shenolikar, S.2
-
19
-
-
0037032835
-
The protein kinase complement of the human genome
-
DOI 10.1126/science.1075762
-
Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S. The protein kinase complement of the human genome. Science 2002; 298:1912-34. (Pubitemid 35425239)
-
(2002)
Science
, vol.298
, Issue.5600
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sudarsanam, S.5
-
20
-
-
0035399464
-
Combinatorial control of protein phosphatase- 1
-
Bollen M. Combinatorial control of protein phosphatase- 1. Trends Biochem Sci 2001; 26:426-31.
-
(2001)
Trends Biochem Sci
, vol.26
, pp. 426-431
-
-
Bollen, M.1
-
21
-
-
0030977268
-
Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1
-
DOI 10.1093/emboj/16.8.1876
-
Egloff MP, Johnson DF, Moorhead G, Cohen PT, Cohen P, Barford D. Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1. EMBO J 1997; 16:1876-87. (Pubitemid 27170949)
-
(1997)
EMBO Journal
, vol.16
, Issue.8
, pp. 1876-1887
-
-
Egloff, M.-P.1
Johnson, D.F.2
Moorhead, G.3
Cohen, P.T.W.4
Cohen, P.5
Barford, D.6
-
22
-
-
64749085585
-
Docking motif-guided mapping of the interactome of protein phosphatase-1
-
Hendrickx A, Beullens M, Ceulemans H, Den AT, Van EA, Nicolaescu E, et al. Docking motif-guided mapping of the interactome of protein phosphatase-1. Chem Biol 2009; 16:365-71.
-
(2009)
Chem Biol
, vol.16
, pp. 365-371
-
-
Hendrickx, A.1
Beullens, M.2
Ceulemans, H.3
Den, A.T.4
Van, E.A.5
Nicolaescu, E.6
-
23
-
-
33644524404
-
Repo-Man recruits PP1 gamma to chromatin and is essential for cell viability
-
Trinkle-Mulcahy L, Andersen J, Lam YW, Moorhead G, Mann M, Lamond AI. Repo-Man recruits PP1 gamma to chromatin and is essential for cell viability. J Cell Biol 2006; 172:679-92.
-
(2006)
J Cell Biol
, vol.172
, pp. 679-692
-
-
Trinkle-Mulcahy, L.1
Andersen, J.2
Lam, Y.W.3
Moorhead, G.4
Mann, M.5
Lamond, A.I.6
-
24
-
-
33749186913
-
Condensin and Repo-Man-PP1 co-operate in the regulation of chromosome architecture during mitosis
-
DOI 10.1038/ncb1475, PII NCB1475
-
Vagnarelli P, Hudson DF, Ribeiro SA, Trinkle- Mulcahy L, Spence JM, Lai F, et al. Condensin and Repo-Man-PP1 co-operate in the regulation of chromosome architecture during mitosis. Nat Cell Biol 2006; 8:1133-42. (Pubitemid 44473609)
-
(2006)
Nature Cell Biology
, vol.8
, Issue.10
, pp. 1133-1142
-
-
Vagnarelli, P.1
Hudson, D.F.2
Ribeiro, S.A.3
Trinkle-Mulcahy, L.4
Spence, J.M.5
Lai, F.6
Farr, C.J.7
Lamond, A.I.8
Earnshaw, W.C.9
-
25
-
-
0032512720
-
Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit
-
DOI 10.1074/jbc.273.7.4089
-
Allen PB, Kwon YG, Nairn AC, Greengard P. Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit. J Biol Chem 1998; 273:4089-95. (Pubitemid 28103276)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.7
, pp. 4089-4095
-
-
Allen, P.B.1
Kwon, Y.-G.2
Nairn, A.C.3
Greengard, P.4
-
26
-
-
0037515628
-
PNUTS, a protein Phosphatase 1 (PP1) NUclear Targeting Subunit: Characterization of its PP1 and RNA-binding domains and regulation by phosphorylation
-
DOI 10.1074/jbc.M209621200
-
Kim YM, Watanabe T, Allen PB, Lee SJ, Greengard P, Nairn AC, et al. PNUTS, a protein phosphatase 1 (PP1) nuclear targeting subunit. Characterization of its PP1- and RNA-binding domains and regulation by phosphorylation. J Biol Chem 2003; 278:13819-28. (Pubitemid 36799920)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.16
, pp. 13819-13828
-
-
Kim, Y.-M.1
Watanabe, T.2
Allen, P.B.3
Kim, Y.-M.4
Lee, S.-J.5
Greengard, P.6
Nairn, A.C.7
Kwon, Y.-G.8
-
27
-
-
0031583952
-
Purification and characterisation of p99, a nuclear modulator of protein phosphatase 1 activity
-
DOI 10.1016/S0014-5793(97)01485-3, PII S0014579397014853
-
Kreivi JP, Trinkle-Mulcahy L, Lyon CE, Morrice NA, Cohen P, Lamond AI. Purification and characterisation of p99, a nuclear modulator of protein phosphatase 1 activity. FEBS Lett 1997; 420:57-62. (Pubitemid 28037200)
-
(1997)
FEBS Letters
, vol.420
, Issue.1
, pp. 57-62
-
-
Kreivi, J.-P.1
Trinkle-Mulcahy, L.2
Lyon, C.E.3
Morrice, N.A.4
Cohen, P.5
Lamond, A.I.6
-
28
-
-
34249050483
-
Protein phosphatase 1 nuclear targeting subunit is a hypoxia inducible gene: Its role in post-translational modification of p53 and MDM2
-
Lee SJ, Lim CJ, Min JK, Lee JK, Kim YM, Lee JY, et al. Protein phosphatase 1 nuclear targeting subunit is a hypoxia inducible gene: its role in post-translational modification of p53 and MDM2. Cell Death Differ 2007; 14:1106-16.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1106-1116
-
-
Lee, S.J.1
Lim, C.J.2
Min, J.K.3
Lee, J.K.4
Kim, Y.M.5
Lee, J.Y.6
-
29
-
-
64049099444
-
TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs
-
Kim H, Lee OH, Xin H, Chen LY, Qin J, Chae HK, et al. TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs. Nat Struct Mol Biol 2009; 16:372-9.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 372-379
-
-
Kim, H.1
Lee, O.H.2
Xin, H.3
Chen, L.Y.4
Qin, J.5
Chae, H.K.6
-
30
-
-
25844468586
-
PNUTS enhances in vitro chromosome decondensation in a PP1-dependent manner
-
DOI 10.1042/BJ20050678
-
Landsverk HB, Kirkhus M, Bollen M, Kuntziger T, Collas P. PNUTS enhances in vitro chromosome decondensation in a PP1-dependent manner. Biochem J 2005; 390:709-17. (Pubitemid 41395354)
-
(2005)
Biochemical Journal
, vol.390
, Issue.3
, pp. 709-717
-
-
Landsverk, H.B.1
Kirkhus, M.2
Bollen, M.3
Kuntziger, T.4
Collas, P.5
-
31
-
-
0037337748
-
Attenuation of a phosphorylation-dependent activator by an HDAC-PP1 complex
-
DOI 10.1038/nsb895
-
Canettieri G, Morantte I, Guzman E, Asahara H, Herzig S, Anderson SD, et al. Attenuation of a phosphorylation-dependent activator by an HDACPP1 complex. Nat Struct Biol 2003; 10:175-81. (Pubitemid 36297986)
-
(2003)
Nature Structural Biology
, vol.10
, Issue.3
, pp. 175-181
-
-
Canettieri, G.1
Morantte, I.2
Guzman, E.3
Asahara, H.4
Herzig, S.5
Anderson, S.D.6
Yates III, J.R.7
Montminy, M.8
-
32
-
-
65949110134
-
Langerhans cell protein 1 (LCP1) binds to PNUTS in the nucleus: Implications for this complex in transcriptional regulation
-
Lee SJ, Lee JK, Maeng YS, Kim YM, Kwon YG. Langerhans cell protein 1 (LCP1) binds to PNUTS in the nucleus: implications for this complex in transcriptional regulation. Exp Mol Med 2009; 41:189-200.
-
(2009)
Exp Mol Med
, vol.41
, pp. 189-200
-
-
Lee, S.J.1
Lee, J.K.2
Maeng, Y.S.3
Kim, Y.M.4
Kwon, Y.G.5
-
33
-
-
77955301844
-
Identification and characterization of a novel human PP1 phosphatase complex
-
Lee JH, You J, Dobrota E, Skalnik DG. Identification and characterization of a novel human PP1 phosphatase complex. J Biol Chem 2010; 285:24466-76.
-
(2010)
J Biol Chem
, vol.285
, pp. 24466-24476
-
-
Lee, J.H.1
You, J.2
Dobrota, E.3
Skalnik, D.G.4
-
34
-
-
41149156291
-
PNUTS forms a trimeric protein complex with GABA(C) receptors and protein phosphatase 1
-
Rose M, Dutting E, Schroder N, Sticht H, Brandstatter JH, Enz R. PNUTS forms a trimeric protein complex with GABA(C) receptors and protein phosphatase 1. Mol Cell Neurosci 2008; 37:808-19.
-
(2008)
Mol Cell Neurosci
, vol.37
, pp. 808-819
-
-
Rose, M.1
Dutting, E.2
Schroder, N.3
Sticht, H.4
Brandstatter, J.H.5
Enz, R.6
-
35
-
-
46249125488
-
How shelterin protects mammalian telomeres
-
Palm W, de LT. How shelterin protects mammalian telomeres. Annu Rev Genet 2008; 42:301-34.
-
(2008)
Annu Rev Genet
, vol.42
, pp. 301-334
-
-
Palm, W.1
De, L.T.2
-
36
-
-
79951959703
-
TOX4 and its binding partners recognize DNA adducts generated by platinum anticancer drugs
-
Puch CB, Barbier E, Kraut A, Coute Y, Fuchs J, Buhot A, et al. TOX4 and its binding partners recognize DNA adducts generated by platinum anticancer drugs. Arch Biochem Biophys 2010.
-
(2010)
Arch Biochem Biophys
-
-
Puch, C.B.1
Barbier, E.2
Kraut, A.3
Coute, Y.4
Fuchs, J.5
Buhot, A.6
-
37
-
-
0031801634
-
Proteins that specifically recognize cisplatin-damaged DNA: A clue to anticancer activity of cisplatin
-
Zlatanova J, Yaneva J, Leuba SH. Proteins that specifically recognize cisplatin-damaged DNA: a clue to anticancer activity of cisplatin. FASEB J 1998; 12:791-9. (Pubitemid 28294669)
-
(1998)
FASEB Journal
, vol.12
, Issue.10
, pp. 791-799
-
-
Zlatanova, J.1
Yaneva, J.2
Leuba, S.H.3
-
38
-
-
23744447715
-
Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells
-
DOI 10.1083/jcb.200411083
-
Kim JS, Krasieva TB, Kurumizaka H, Chen DJ, Taylor AM, Yokomori K. Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells. J Cell Biol 2005; 170:341-7. (Pubitemid 41126934)
-
(2005)
Journal of Cell Biology
, vol.170
, Issue.3
, pp. 341-347
-
-
Kim, J.-S.1
Krasieva, T.B.2
Kurumizaka, H.3
Chen, D.J.4
Taylor, A.M.R.5
Yokomori, K.6
-
39
-
-
33845484385
-
Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4
-
DOI 10.1073/pnas.0609061103
-
Mari PO, Florea BI, Persengiev SP, Verkaik NS, Bruggenwirth HT, Modesti M, et al. Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4. Proc Natl Acad Sci USA 2006; 103:18597-602. (Pubitemid 44913456)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.49
, pp. 18597-18602
-
-
Mari, P.-O.1
Florea, B.I.2
Persengiev, S.P.3
Verkaik, N.S.4
Bruggenwirth, H.T.5
Modesti, M.6
Giglia-Mari, G.7
Bezstarosti, K.8
Demmers, J.A.A.9
Luider, T.M.10
Houtsmuller, A.B.11
Van Gent, D.C.12
-
40
-
-
0017130995
-
Separation and characterization of two phosphorylase phosphatase inhibitors from rabbit skeletal muscle
-
Huang FL, Glinsmann WH. Separation and characterization of two phosphorylase phosphatase inhibitors from rabbit skeletal muscle. Eur J Biochem 1976; 70:419-26.
-
(1976)
Eur J Biochem
, vol.70
, pp. 419-426
-
-
Huang, F.L.1
Glinsmann, W.H.2
-
41
-
-
58149290228
-
Phosphatase inhibitor-2 balances protein phosphatase 1 and aurora B kinase for chromosome segregation and cytokinesis in human retinal epithelial cells
-
Wang W, Stukenberg PT, Brautigan DL. Phosphatase inhibitor-2 balances protein phosphatase 1 and aurora B kinase for chromosome segregation and cytokinesis in human retinal epithelial cells. Mol Biol Cell 2008; 19:4852-62.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 4852-4862
-
-
Wang, W.1
Stukenberg, P.T.2
Brautigan, D.L.3
-
42
-
-
0036829505
-
Ionizing radiation activates nuclear protein phosphatase-1 by ATM-dependent dephosphorylation
-
DOI 10.1074/jbc.M207519200
-
Guo CY, Brautigan DL, Larner JM. Ionizing radiation activates nuclear protein phosphatase-1 by ATM-dependent dephosphorylation. J Biol Chem 2002; 277:41756-61. (Pubitemid 35257484)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.44
, pp. 41756-41761
-
-
Guo, C.Y.1
Brautigan, D.L.2
Larner, J.M.3
-
43
-
-
37549021501
-
Role for KAP1 serine 824 phosphorylation and sumoylation/desumoylation switch in regulating KAP1-mediated transcriptional repression
-
Li X, Lee YK, Jeng JC, Yen Y, Schultz DC, Shih HM, et al. Role for KAP1 serine 824 phosphorylation and sumoylation/desumoylation switch in regulating KAP1-mediated transcriptional repression. J Biol Chem 2007; 282:36177-89.
-
(2007)
J Biol Chem
, vol.282
, pp. 36177-36189
-
-
Li, X.1
Lee, Y.K.2
Jeng, J.C.3
Yen, Y.4
Schultz, D.C.5
Shih, H.M.6
-
44
-
-
0029858585
-
KAP-1, a novel corepressor for the highly conserved KRAB repression domain
-
Friedman JR, Fredericks WJ, Jensen DE, Speicher DW, Huang XP, Neilson EG, et al. KAP-1, a novel corepressor for the highly conserved KRAB repression domain. Genes Dev 1996; 10:2067-78. (Pubitemid 26346114)
-
(1996)
Genes and Development
, vol.10
, Issue.16
, pp. 2067-2078
-
-
Friedman, J.R.1
Fredericks, W.J.2
Jensen, D.E.3
Speicher, D.W.4
Huang, X.-P.5
Neilson, E.G.6
Rauscher III, F.J.7
-
45
-
-
47349107760
-
ATM Signaling Facilitates Repair of DNA Double-Strand Breaks Associated with Heterochromatin
-
DOI 10.1016/j.molcel.2008.05.017, PII S109727650800395X
-
Goodarzi AA, Noon AT, Deckbar D, Ziv Y, Shiloh Y, Lobrich M, et al. ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol Cell 2008; 31:167-77. (Pubitemid 352001394)
-
(2008)
Molecular Cell
, vol.31
, Issue.2
, pp. 167-177
-
-
Goodarzi, A.A.1
Noon, A.T.2
Deckbar, D.3
Ziv, Y.4
Shiloh, Y.5
Lobrich, M.6
Jeggo, P.A.7
-
46
-
-
75949122330
-
53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair
-
Noon AT, Shibata A, Rief N, Lobrich M, Stewart GS, Jeggo PA, et al. 53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair. Nat Cell Biol 2010; 12:177-84.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 177-184
-
-
Noon, A.T.1
Shibata, A.2
Rief, N.3
Lobrich, M.4
Stewart, G.S.5
Jeggo, P.A.6
-
47
-
-
77953819028
-
SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1
-
Li X, Lin HH, Chen H, Xu X, Shih HM, Ann DK. SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1. Sci Signal 2010; 3:32.
-
(2010)
Sci Signal
, vol.3
, pp. 32
-
-
Li, X.1
Lin, H.H.2
Chen, H.3
Xu, X.4
Shih, H.M.5
Ann, D.K.6
-
48
-
-
75149189204
-
BRCA1 and its toolbox for the maintenance of genome integrity
-
Huen MS, Sy SM, Chen J. BRCA1 and its toolbox for the maintenance of genome integrity. Nat Rev Mol Cell Biol 2010; 11:138-48.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 138-148
-
-
Huen, M.S.1
Sy, S.M.2
Chen, J.3
-
49
-
-
0035942190
-
Cancer-predisposing mutations within the RING domain of BRCA1: Loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity
-
DOI 10.1073/pnas.081068398
-
Ruffner H, Joazeiro CA, Hemmati D, Hunter T, Verma IM. Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity. Proc Natl Acad Sci USA 2001; 98:5134-9. (Pubitemid 32397095)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.9
, pp. 5134-5139
-
-
Ruffner, H.1
Joazeiro, C.A.P.2
Hemmati, D.3
Hunter, T.4
Verma, I.M.5
-
50
-
-
0030850047
-
Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage
-
DOI 10.1016/S0092-8674(00)80503-6
-
Scully R, Chen J, Ochs RL, Keegan K, Hoekstra M, Feunteun J, et al. Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell 1997; 90:425-35. (Pubitemid 27347233)
-
(1997)
Cell
, vol.90
, Issue.3
, pp. 425-435
-
-
Scully, R.1
Chen, J.2
Ochs, R.L.3
Keegan, K.4
Hoekstra, M.5
Feunteun, J.6
Livingston, D.M.7
-
51
-
-
59049091728
-
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
-
Doil C, Mailand N, Bekker-Jensen S, Menard P, Larsen DH, Pepperkok R, et al. RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell 2009; 136:435-46.
-
(2009)
Cell
, vol.136
, pp. 435-446
-
-
Doil, C.1
Mailand, N.2
Bekker-Jensen, S.3
Menard, P.4
Larsen, D.H.5
Pepperkok, R.6
-
52
-
-
59049103900
-
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage
-
Stewart GS, Panier S, Townsend K, Al-Hakim AK, Kolas NK, Miller ES, et al. The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell 2009; 136:420-34.
-
(2009)
Cell
, vol.136
, pp. 420-434
-
-
Stewart, G.S.1
Panier, S.2
Townsend, K.3
Al-Hakim, A.K.4
Kolas, N.K.5
Miller, E.S.6
-
53
-
-
66349096607
-
PALB2 is an integral component of the BRCA complex required for homologous recombination repair
-
Sy SM, Huen MS, Chen J. PALB2 is an integral component of the BRCA complex required for homologous recombination repair. Proc Natl Acad Sci USA 2009; 106:7155-60.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 7155-7160
-
-
Sy, S.M.1
Huen, M.S.2
Chen, J.3
-
54
-
-
0035032649
-
2-phase checkpoints after ionizing irradiation
-
DOI 10.1128/MCB.21.10.3445-3450.2001
-
Xu B, Kim S, Kastan MB. Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation. Mol Cell Biol 2001; 21:3445-50. (Pubitemid 32381780)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.10
, pp. 3445-3450
-
-
Xu, B.1
Kim, S.-T.2
Kastan, M.B.3
-
56
-
-
34447093273
-
Identification and functional characterization of a PP1-binding site in BRCA1
-
Hsu LC. Identification and functional characterization of a PP1-binding site in BRCA1. Biochem Biophys Res Commun 2007; 360:507-12.
-
(2007)
Biochem Biophys Res Commun
, vol.360
, pp. 507-512
-
-
Hsu, L.C.1
-
57
-
-
0037112506
-
Regulation of BRCA1 phosphorylation by interaction with protein phosphatase 1alpha
-
Liu Y, Virshup DM, White RL, Hsu LC. Regulation of BRCA1 phosphorylation by interaction with protein phosphatase 1alpha. Cancer Res 2002; 62:6357-61. (Pubitemid 35364085)
-
(2002)
Cancer Research
, vol.62
, Issue.22
, pp. 6357-6361
-
-
Liu, Y.1
Virshup, D.M.2
White, R.L.3
Hsu, L.-C.4
-
59
-
-
54949102033
-
A PP1-binding motif present in BRCA1 plays a role in its DNA repair function
-
Yu YM, Pace SM, Allen SR, Deng CX, Hsu LC. A PP1-binding motif present in BRCA1 plays a role in its DNA repair function. Int J Biol Sci 2008; 4:352-61.
-
(2008)
Int J Biol Sci
, vol.4
, pp. 352-361
-
-
Yu, Y.M.1
Pace, S.M.2
Allen, S.R.3
Deng, C.X.4
Hsu, L.C.5
-
60
-
-
0027251721
-
The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit
-
Durfee T, Becherer K, Chen PL, Yeh SH, Yang Y, Kilburn AE, et al. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes Dev 1993; 7:555-69. (Pubitemid 23125257)
-
(1993)
Genes and Development
, vol.7
, Issue.4
, pp. 555-569
-
-
Durfee, T.1
Becherer, K.2
Chen, P.-L.3
Yeh, S.-H.4
Yang, Y.5
Kilburn, A.E.6
Lee, W.-H.7
Elledge, S.J.8
-
61
-
-
33644519320
-
Direct interaction between the catalytic subunit of Protein Phosphatase 1 and pRb
-
Vietri M, Bianchi M, Ludlow JW, Mittnacht S, Villa- Moruzzi E. Direct interaction between the catalytic subunit of Protein Phosphatase 1 and pRb. Cancer Cell Int 2006; 6:3.
-
(2006)
Cancer Cell Int
, vol.6
, pp. 3
-
-
Vietri, M.1
Bianchi, M.2
Ludlow, J.W.3
Mittnacht, S.4
Villa- Moruzzi, E.5
-
62
-
-
77956340499
-
An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein
-
Hirschi A, Cecchini M, Steinhardt RC, Schamber MR, Dick FA, Rubin SM. An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein. Nat Struct Mol Biol 2010; 17:1051-7.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 1051-1057
-
-
Hirschi, A.1
Cecchini, M.2
Steinhardt, R.C.3
Schamber, M.R.4
Dick, F.A.5
Rubin, S.M.6
-
63
-
-
33748028804
-
Cell cycle control and beyond: Emerging roles for the retinoblastoma gene family
-
DOI 10.1038/sj.onc.1209652, PII 1209652
-
Genovese C, Trani D, Caputi M, Claudio PP. Cell cycle control and beyond: emerging roles for the retinoblastoma gene family. Oncogene 2006; 25:5201-9. (Pubitemid 44299078)
-
(2006)
Oncogene
, vol.25
, Issue.38
, pp. 5201-5209
-
-
Genovese, C.1
Trani, D.2
Caputi, M.3
Claudio, P.P.4
-
64
-
-
0027458292
-
Regulation of cell cycle progression and nuclear affinity of the retinoblastoma protein by protein phosphatases
-
DOI 10.1073/pnas.90.2.388
-
Alberts AS, Thorburn AM, Shenolikar S, Mumby MC, Feramisco JR. Regulation of cell cycle progression and nuclear affinity of the retinoblastoma protein by protein phosphatases. Proc Natl Acad Sci USA 1993; 90:388-92. (Pubitemid 23028867)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.2
, pp. 388-392
-
-
Alberts, A.S.1
Thorburn, A.M.2
Shenolikar, S.3
Mumby, M.C.4
Feramisco, J.R.5
-
65
-
-
0027455644
-
Specific enzymatic dephosphorylation of the retinoblastoma protein
-
Ludlow JW, Glendening CL, Livingston DM, DeCarprio JA. Specific enzymatic dephosphorylation of the retinoblastoma protein. Mol Cell Biol 1993; 13:367-72. (Pubitemid 23006914)
-
(1993)
Molecular and Cellular Biology
, vol.13
, Issue.1
, pp. 367-372
-
-
Ludlow, J.W.1
Glendening, C.L.2
Livingston, D.M.3
DeCaprio, J.A.4
-
66
-
-
33747339919
-
Dephosphorylation of Rb (Thr- 821) in response to cell stress
-
Krucher NA, Rubin E, Tedesco VC, Roberts MH, Sherry TC, De LG. Dephosphorylation of Rb (Thr- 821) in response to cell stress. Exp Cell Res 2006; 312:2757-63.
-
(2006)
Exp Cell Res
, vol.312
, pp. 2757-2763
-
-
Krucher, N.A.1
Rubin, E.2
Tedesco, V.C.3
Roberts, M.H.4
Sherry, T.C.5
De, L.G.6
-
67
-
-
0036389746
-
PNUTS (phosphatase nuclear targeting subunit) inhibits retinoblastoma-directed PP1 activity
-
Udho E, Tedesco VC, Zygmunt A, Krucher NA. PNUTS (phosphatase nuclear targeting subunit) inhibits retinoblastoma-directed PP1 activity. Biochem Biophys Res Commun 2002; 297:463-7.
-
(2002)
Biochem Biophys Res Commun
, vol.297
, pp. 463-467
-
-
Udho, E.1
Tedesco, V.C.2
Zygmunt, A.3
Krucher, N.A.4
-
68
-
-
46749089975
-
Reduced expression of PNUTS leads to activation of Rb-phosphatase and caspase-mediated apoptosis
-
De LG, Sherry TC, Krucher NA. Reduced expression of PNUTS leads to activation of Rb-phosphatase and caspase-mediated apoptosis. Cancer Biol Ther 2008; 7:833-41.
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 833-841
-
-
De, L.G.1
Sherry, T.C.2
Krucher, N.A.3
-
69
-
-
34347232361
-
Phactr4 regulates neural tube and optic fissure closure by controlling PP1-, Rb- and E2F1-regulated cell cycle progression
-
Kim TH, Goodman J, Anderson KV, Niswander L. Phactr4 regulates neural tube and optic fissure closure by controlling PP1-, Rb- and E2F1-regulated cell cycle progression. Dev Cell 2007; 13:87-102.
-
(2007)
Dev Cell
, vol.13
, pp. 87-102
-
-
Kim, T.H.1
Goodman, J.2
Anderson, K.V.3
Niswander, L.4
-
70
-
-
70349286051
-
New insights into the expanding complexity of the tumor suppressor ASPP2
-
Kampa KM, Bonin M, Lopez CD. New insights into the expanding complexity of the tumor suppressor ASPP2. Cell Cycle 2009; 8:2871-6.
-
(2009)
Cell Cycle
, vol.8
, pp. 2871-2876
-
-
Kampa, K.M.1
Bonin, M.2
Lopez, C.D.3
-
71
-
-
0037418624
-
The ASPP family: Deciding between life and death after DNA damage
-
DOI 10.1016/S0378-4274(02)00421-6, PII S0378427402004216
-
Slee EA, Lu X. The ASPP family: deciding between life and death after DNA damage. Toxicol Lett 2003; 139:81-7. (Pubitemid 36298965)
-
(2003)
Toxicology Letters
, vol.139
, Issue.2-3
, pp. 81-87
-
-
Slee, E.A.1
Lu, X.2
-
72
-
-
0029617851
-
Protein phosphatase 1 interacts with p53BP2, a protein which binds to the tumour suppressor p53
-
DOI 10.1016/0014-5793(95)01347-4
-
Helps NR, Barker HM, Elledge SJ, Cohen PT. Protein phosphatase 1 interacts with p53BP2, a protein which binds to the tumour suppressor p53. FEBS Lett 1995; 377:295-300. (Pubitemid 26025716)
-
(1995)
FEBS Letters
, vol.377
, Issue.3
, pp. 295-300
-
-
Helps, N.R.1
Barker, H.M.2
Elledge, S.J.3
Cohen, P.T.W.4
-
73
-
-
79953153876
-
PP1 Cooperates with ASPP2 to dephosphorylate and activate TAZ
-
Liu CY, Lv X, Li T, Xu Y, Zhou X, Zhao S, et al. PP1 Cooperates with ASPP2 to dephosphorylate and activate TAZ. J Biol Chem 2010.
-
(2010)
J Biol Chem
-
-
Liu, C.Y.1
Lv, X.2
Li, T.3
Xu, Y.4
Zhou, X.5
Zhao, S.6
-
74
-
-
0037081563
-
Protein phosphatase 1 - Targeted in many directions
-
Cohen PT. Protein phosphatase 1 - targeted in many directions. J Cell Sci 2002; 115:241-56. (Pubitemid 34145174)
-
(2002)
Journal of Cell Science
, vol.115
, Issue.2
, pp. 241-256
-
-
Cohen, P.T.W.1
-
75
-
-
42349088170
-
A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells
-
DOI 10.1158/0008-5472.CAN-07-2696
-
Chan SW, Lim CJ, Guo K, Ng CP, Lee I, Hunziker W, et al. A role for TAZ in migration, invasion and tumorigenesis of breast cancer cells. Cancer Res 2008; 68:2592-8. (Pubitemid 351556257)
-
(2008)
Cancer Research
, vol.68
, Issue.8
, pp. 2592-2598
-
-
Siew, W.C.1
Chun, J.L.2
Guo, K.3
Chee, P.N.4
Lee, I.5
Hunziker, W.6
Zeng, Q.7
Hong, W.8
-
76
-
-
41149098966
-
TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway
-
DOI 10.1128/MCB.01874-07
-
Lei QY, Zhang H, Zhao B, Zha ZY, Bai F, Pei XH, et al. TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway. Mol Cell Biol 2008; 28:2426-36. (Pubitemid 351429986)
-
(2008)
Molecular and Cellular Biology
, vol.28
, Issue.7
, pp. 2426-2436
-
-
Lei, Q.-Y.1
Zhang, H.2
Zhao, B.3
Zha, Z.-Y.4
Bai, F.5
Pei, X.-H.6
Zhao, S.7
Xiong, Y.8
Guan, K.-L.9
-
77
-
-
0030971097
-
Mammalian GADD34, an apoptosis- and DNA damage-inducible gene
-
DOI 10.1074/jbc.272.21.13731
-
Hollander MC, Zhan Q, Bae I, Fornace AJ Jr. Mammalian GADD34, an apoptosis- and DNA damage- inducible gene. J Biol Chem 1997; 272:13731-7. (Pubitemid 27224809)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.21
, pp. 13731-13737
-
-
Hollander, M.C.1
Zhan, Q.2
Bae, I.3
Fornace Jr., A.J.4
-
78
-
-
0032850199
-
Leukemic HRX fusion proteins inhibit GADD34-induced apoptosis and associate with the GADD34 and hSNF5/INI1 proteins
-
Adler HT, Chinery R, Wu DY, Kussick SJ, Payne JM, Fornace AJ Jr, et al. Leukemic HRX fusion proteins inhibit GADD34-induced apoptosis and associate with the GADD34 and hSNF5/INI1 proteins. Mol Cell Biol 1999; 19:7050-60. (Pubitemid 29441887)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.10
, pp. 7050-7060
-
-
Adler, H.T.1
Chinery, R.2
Wu, D.Y.3
Kussick, S.J.4
Payne, J.M.5
Fornace Jr., A.J.6
Tkachuk, D.C.7
-
79
-
-
0035964285
-
Interaction between growth arrest-DNA damage protein 34 and Src kinase Lyn negatively regulates genotoxic apoptosis
-
DOI 10.1073/pnas.191130798
-
Grishin AV, Azhipa O, Semenov I, Corey SJ. Interaction between growth arrest-DNA damage protein 34 and Src kinase Lyn negatively regulates genotoxic apoptosis. Proc Natl Acad Sci USA 2001; 98:10172-7. (Pubitemid 32802993)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.18
, pp. 10172-10177
-
-
Grishin, A.V.1
Azhipa, O.2
Semenov, I.3
Corey, S.J.4
-
80
-
-
0035947778
-
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha
-
Novoa I, Zeng H, Harding HP, Ron D. Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha. JCell Biol 2001; 153:1011-22.
-
(2001)
JCell Biol
, vol.153
, pp. 1011-1022
-
-
Novoa, I.1
Zeng, H.2
Harding, H.P.3
Ron, D.4
-
81
-
-
1642539976
-
GADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptor
-
DOI 10.1083/jcb.200307151
-
Shi W, Sun C, He B, Xiong W, Shi X, Yao D, et al. GADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptor. J Cell Biol 2004; 164:291-300. (Pubitemid 38133948)
-
(2004)
Journal of Cell Biology
, vol.164
, Issue.2
, pp. 291-300
-
-
Shi, W.1
Sun, C.2
He, B.3
Xiong, W.4
Shi, X.5
Yao, D.6
Cao, X.7
-
82
-
-
0035854731
-
Ultraviolet irradiation blocks cellular responses to transforming growth factor-beta by downregulating its type-II receptor and inducing Smad7
-
Quan T, He T, Voorhees JJ, Fisher GJ. Ultraviolet irradiation blocks cellular responses to transforming growth factor-beta by downregulating its type-II receptor and inducing Smad7. J Biol Chem 2001; 276:26349-56.
-
(2001)
J Biol Chem
, vol.276
, pp. 26349-26356
-
-
Quan, T.1
He, T.2
Voorhees, J.J.3
Fisher, G.J.4
-
83
-
-
2942594540
-
Protein phosphatase 1, but not protein phosphatase 2A, dephosphorylates DNA-damaging stress-induced phospho-serine 15 of p53
-
DOI 10.1016/j.febslet.2004.04.066, PII S0014579304005113
-
Haneda M, Kojima E, Nishikimi A, Hasegawa T, Nakashima I, Isobe K. Protein phosphatase 1, but not protein phosphatase 2A, dephosphorylates DNA-damaging stress-induced phospho-serine 15 of p53. FEBS Lett 2004; 567:171-4. (Pubitemid 38748387)
-
(2004)
FEBS Letters
, vol.567
, Issue.2-3
, pp. 171-174
-
-
Haneda, M.1
Kojima, E.2
Nishikimi, A.3
Hasegawa, T.4
Nakashima, I.5
Isobe, K.-I.6
-
84
-
-
4143051237
-
Inhibition of centrosome separation after DNA damage: A role for Nek2
-
DOI 10.1667/RR3211
-
Fletcher L, Cerniglia GJ, Nigg EA, Yend TJ, Muschel RJ. Inhibition of centrosome separation after DNA damage: a role for Nek2. Radiat Res 2004; 162:128-35. (Pubitemid 39100011)
-
(2004)
Radiation Research
, vol.162
, Issue.2
, pp. 128-135
-
-
Fletcher, L.1
Cerniglia, G.J.2
Nigg, E.A.3
Yen, T.J.4
Muschel, R.J.5
-
85
-
-
0032518798
-
A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators
-
DOI 10.1093/emboj/17.2.470
-
Fry AM, Meraldi P, Nigg EA. A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators. EMBO J 1998; 17:470-81. (Pubitemid 28045488)
-
(1998)
EMBO Journal
, vol.17
, Issue.2
, pp. 470-481
-
-
Fry, A.M.1
Meraldi, P.2
Nigg, E.A.3
-
86
-
-
0028058885
-
Cell cycle-dependent expression of Nek2, a novel human protein kinase related to the NIMA mitotic regulator of Aspergillus nidulans
-
Schultz SJ, Fry AM, Sutterlin C, Ried T, Nigg EA. Cell cycle-dependent expression of Nek2, a novel human protein kinase related to the NIMA mitotic regulator of Aspergillus nidulans. Cell Growth Differ 1994; 5:625-35. (Pubitemid 24252327)
-
(1994)
Cell Growth and Differentiation
, vol.5
, Issue.6
, pp. 625-635
-
-
Schultz, S.J.1
Fry, A.M.2
Sutterlin, C.3
Ried, T.4
Nigg, E.A.5
-
87
-
-
0034661499
-
NIMA-related kinase 2 (Nek2), a cell-cycle-regulated protein kinase localized to centrosomes, is complexed to protein phosphatase 1
-
DOI 10.1042/0264-6021:3490509
-
Helps NR, Luo X, Barker HM, Cohen PT. NIMA-related kinase 2 (Nek2), a cell cycle-regulated protein kinase localized to centrosomes, is complexed to protein phosphatase 1. Biochem J 2000; 349:509-18. (Pubitemid 30465786)
-
(2000)
Biochemical Journal
, vol.349
, Issue.2
, pp. 509-518
-
-
Helps, N.R.1
Luo, X.2
Barker, H.M.3
Cohen, P.T.W.4
-
88
-
-
0034753402
-
Centrosome cohesion is regulated by a balance of kinase and phosphatase activities
-
Meraldi P, Nigg EA. Centrosome cohesion is regulated by a balance of kinase and phosphatase activities. J Cell Sci 2001; 114:3749-57. (Pubitemid 33041056)
-
(2001)
Journal of Cell Science
, vol.114
, Issue.20
, pp. 3749-3757
-
-
Meraldi, P.1
Nigg, E.A.2
-
89
-
-
33847008755
-
Protein phosphatase-1alpha regulates centrosome splitting through Nek2
-
Mi J, Guo C, Brautigan DL, Larner JM. Protein phosphatase-1alpha regulates centrosome splitting through Nek2. Cancer Res 2007; 67:1082-9.
-
(2007)
Cancer Res
, vol.67
, pp. 1082-1089
-
-
Mi, J.1
Guo, C.2
Brautigan, D.L.3
Larner, J.M.4
-
90
-
-
34250865564
-
CDC25 phosphatases in cancer cells: Key players? Good targets?
-
Boutros R, Lobjois V, Ducommun B. CDC25 phosphatases in cancer cells: key players? Good targets? Nat Rev Cancer 2007; 7:495-507.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 495-507
-
-
Boutros, R.1
Lobjois, V.2
Ducommun, B.3
-
91
-
-
0025917804
-
CDC25 is a nuclear protein required for the initiation of mitosis in human cells
-
Millar JB, Blevitt J, Gerace L, Sadhu K, Featherstone C, Russell P. p55CDC25 is a nuclear protein required for the initiation of mitosis in human cells. Proc Natl Acad Sci USA 1991; 88:10500-4. (Pubitemid 21915863)
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.23
, pp. 10500-10504
-
-
Millar, J.B.A.1
Blevitt, J.2
Gerace, L.3
Sadhu, K.4
Featherstone, C.5
Russell, P.6
-
92
-
-
0037804567
-
Dual phosphorylation controls Cdc25 phosphatases and mitotic entry
-
DOI 10.1038/ncb994
-
Bulavin DV, Higashimoto Y, Demidenko ZN, Meek S, Graves P, Phillips C, et al. Dual phosphorylation controls Cdc25 phosphatases and mitotic entry. Nat Cell Biol 2003; 5:545-51. (Pubitemid 36781089)
-
(2003)
Nature Cell Biology
, vol.5
, Issue.6
, pp. 545-551
-
-
Bulavin, D.V.1
Higashimoto, Y.2
Demidenko, Z.N.3
Meek, S.4
Graves, P.5
Phillips, C.6
Zhao, H.7
Moody, S.A.8
Appella, E.9
Piwnica-Worms, H.10
Fornace Jr., A.J.11
-
93
-
-
0032974109
-
Cytoplasmic localization of human cdc25C during interphase requires an intact 14-3-3 binding site
-
Dalal SN, Schweitzer CM, Gan J, Decaprio JA. Cytoplasmic localization of human cdc25C during interphase requires an intact 14-3-3 binding site. MolCell Biol 1999; 19:4465-79. (Pubitemid 29242020)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.6
, pp. 4465-4479
-
-
Dalal, S.N.1
Schweitzer, C.M.2
Gan, J.3
DeCaprio, J.A.4
-
94
-
-
0032484084
-
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase
-
Matsuoka S, Huang M, Elledge SJ. Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science 1998; 282:1893-7. (Pubitemid 28555269)
-
(1998)
Science
, vol.282
, Issue.5395
, pp. 1893-1897
-
-
Matsuoka, S.1
Huang, M.2
Elledge, S.J.3
-
95
-
-
0030611095
-
2 checkpoint control: Regulation of 14-3-3 protein binding by phosphorylation of Cdc25c on serine-216
-
DOI 10.1126/science.277.5331.1501
-
Peng CY, Graves PR, Thoma RS, Wu Z, Shaw AS, Piwnica-Worms H. Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science 1997; 277:1501-5. (Pubitemid 27449237)
-
(1997)
Science
, vol.277
, Issue.5331
, pp. 1501-1505
-
-
Peng, C.-Y.1
Graves, P.R.2
Thoma, R.S.3
Wu, Z.4
Shaw, A.S.5
Piwnica-Worms, H.6
-
96
-
-
0030867582
-
Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25
-
DOI 10.1126/science.277.5331.1497
-
Sanchez Y, Wong C, Thoma RS, Richman R, Wu Z, Piwnica-Worms H, et al. Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science 1997; 277:1497-501. (Pubitemid 27449236)
-
(1997)
Science
, vol.277
, Issue.5331
, pp. 1497-1501
-
-
Sanchez, Y.1
Wong, C.2
Thoma, R.S.3
Richman, R.4
Wu, Z.5
Piwnica-Worms, H.6
Elledge, S.J.7
-
97
-
-
0242389822
-
PP1 control of M phase entry exerted through 14-3-3-regulated Cdc25 dephosphorylation
-
DOI 10.1093/emboj/cdg545
-
Margolis SS, Walsh S, Weiser DC, Yoshida M, Shenolikar S, Kornbluth S. PP1 control of M phase entry exerted through 14-3-3-regulated Cdc25 dephosphorylation. EMBO J 2003; 22:5734-45. (Pubitemid 37408813)
-
(2003)
EMBO Journal
, vol.22
, Issue.21
, pp. 5734-5745
-
-
Margolis, S.S.1
Walsh, S.2
Weiser, D.C.3
Yoshida, M.4
Shenolikar, S.5
Kornbluth, S.6
-
98
-
-
0034997233
-
Absence of apparent phenotype in mice lacking Cdc25C protein phosphatase
-
DOI 10.1128/MCB.21.12.3853-3861.2001
-
Chen MS, Hurov J, White LS, Woodford-Thomas T, Piwnica-Worms H. Absence of apparent phenotype in mice lacking Cdc25C protein phosphatase. Mol Cell Biol 2001; 21:3853-61. (Pubitemid 32476448)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.12
, pp. 3853-3861
-
-
Chen, M.-S.1
Hurov, J.2
White, L.S.3
Woodford-Thomas, T.4
Piwnica-Worms, H.5
-
99
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
DOI 10.1074/jbc.273.10.5858
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 1998; 273:5858-68. (Pubitemid 28124064)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.10
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
100
-
-
65149084552
-
Crosstalk between histone modifications during the DNA damage response
-
van AH, Gasser SM. Crosstalk between histone modifications during the DNA damage response. Trends Cell Biol 2009; 19:207-17.
-
(2009)
Trends Cell Biol
, vol.19
, pp. 207-217
-
-
Van, A.H.1
Gasser, S.M.2
-
101
-
-
73549116091
-
Dephosphorylation of gamma H2A by Glc7/protein phosphatase 1 promotes recovery from inhibition of DNA replication
-
Bazzi M, Mantiero D, Trovesi C, Lucchini G, Longhese MP. Dephosphorylation of gamma H2A by Glc7/protein phosphatase 1 promotes recovery from inhibition of DNA replication. Mol Cell Biol 2010; 30:131-45.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 131-145
-
-
Bazzi, M.1
Mantiero, D.2
Trovesi, C.3
Lucchini, G.4
Longhese, M.P.5
-
102
-
-
46149117962
-
A PP4-Phosphatase Complex Dephosphorylates gamma-H2AX Generated during DNA Replication
-
DOI 10.1016/j.molcel.2008.05.016, PII S1097276508003948
-
Chowdhury D, Xu X, Zhong X, Ahmed F, Zhong J, Liao J, et al. A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication. Mol Cell 2008; 31:33-46. (Pubitemid 351905923)
-
(2008)
Molecular Cell
, vol.31
, Issue.1
, pp. 33-46
-
-
Chowdhury, D.1
Xu, X.2
Zhong, X.3
Ahmed, F.4
Zhong, J.5
Liao, J.6
Dykxhoorn, D.M.7
Weinstock, D.M.8
Pfeifer, G.P.9
Lieberman, J.10
-
103
-
-
31444445458
-
A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery
-
DOI 10.1038/nature04384, PII NATURE04384
-
Keogh MC, Kim JA, Downey M, Fillingham J, Chowdhury D, Harrison JC, et al. A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery. Nature 2006; 439:497-501. (Pubitemid 43152843)
-
(2006)
Nature
, vol.439
, Issue.7075
, pp. 497-501
-
-
Keogh, M.-C.1
Kim, J.-A.2
Downey, M.3
Fillingham, J.4
Chowdhury, D.5
Harrison, J.C.6
Onishi, M.7
Datta, N.8
Galicia, S.9
Emili, A.10
Lieberman, J.11
Shen, X.12
Buratowski, S.13
Haber, J.E.14
Durocher, D.15
Greenblatt, J.F.16
Krogan, N.J.17
-
104
-
-
53249100305
-
PP4 is a gamma H2AX phosphatase required for recovery from the DNA damage checkpoint
-
Nakada S, Chen GI, Gingras AC, Durocher D. PP4 is a gamma H2AX phosphatase required for recovery from the DNA damage checkpoint. EMBO Rep 2008; 9:1019-26.
-
(2008)
EMBO Rep
, vol.9
, pp. 1019-1026
-
-
Nakada, S.1
Chen, G.I.2
Gingras, A.C.3
Durocher, D.4
-
105
-
-
28444483130
-
gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair
-
DOI 10.1016/j.molcel.2005.10.003, PII S1097276505016734
-
Chowdhury D, Keogh MC, Ishii H, Peterson CL, Buratowski S, Lieberman J. gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair. Mol Cell 2005; 20:801-9. (Pubitemid 41740701)
-
(2005)
Molecular Cell
, vol.20
, Issue.5
, pp. 801-809
-
-
Chowdhury, D.1
Keogh, M.-C.2
Ishii, H.3
Peterson, C.L.4
Buratowski, S.5
Lieberman, J.6
-
106
-
-
77952825226
-
Wip1 directly dephosphorylates gamma- H2AX and attenuates the DNA damage response
-
Cha H, Lowe JM, Li H, Lee JS, Belova GI, Bulavin DV, et al. Wip1 directly dephosphorylates gamma- H2AX and attenuates the DNA damage response. Cancer Res 2010; 70:4112-22.
-
(2010)
Cancer Res
, vol.70
, pp. 4112-4122
-
-
Cha, H.1
Lowe, J.M.2
Li, H.3
Lee, J.S.4
Belova, G.I.5
Bulavin, D.V.6
-
107
-
-
77951064789
-
Wip1 phosphatase is associated with chromatin and dephosphorylates gammaH2AX to promote checkpoint inhibition
-
Macurek L, Lindqvist A, Voets O, Kool J, Vos HR, Medema RH. Wip1 phosphatase is associated with chromatin and dephosphorylates gammaH2AX to promote checkpoint inhibition. Oncogene 2010; 29:2281-91.
-
(2010)
Oncogene
, vol.29
, pp. 2281-2291
-
-
Macurek, L.1
Lindqvist, A.2
Voets, O.3
Kool, J.4
Vos, H.R.5
Medema, R.H.6
-
108
-
-
77951244965
-
Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma- H2AX and suppresses DNA double strand break repair
-
Moon SH, Lin L, Zhang X, Nguyen TA, Darlington Y, Waldman AS, et al. Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma- H2AX and suppresses DNA double strand break repair. J Biol Chem 2010; 285:12935-47.
-
(2010)
J Biol Chem
, vol.285
, pp. 12935-12947
-
-
Moon, S.H.1
Lin, L.2
Zhang, X.3
Nguyen, T.A.4
Darlington, Y.5
Waldman, A.S.6
-
109
-
-
38649118240
-
Chk1 Is a Histone H3 Threonine 11 Kinase that Regulates DNA Damage-Induced Transcriptional Repression
-
DOI 10.1016/j.cell.2007.12.013, PII S009286740701611X
-
Shimada M, Niida H, Zineldeen DH, Tagami H, Tanaka M, Saito H, et al. Chk1 is a histone H3 threonine 11 kinase that regulates DNA damage-induced transcriptional repression. Cell 2008; 132:221-32. (Pubitemid 351172429)
-
(2008)
Cell
, vol.132
, Issue.2
, pp. 221-232
-
-
Shimada, M.1
Niida, H.2
Zineldeen, D.H.3
Tagami, H.4
Tanaka, M.5
Saito, H.6
Nakanishi, M.7
-
110
-
-
78049323483
-
Protein phosphatase 1gamma is responsible for dephosphorylation of histone H3 at Thr 11 after DNA damage
-
Shimada M, Haruta M, Niida H, Sawamoto K, Nakanishi M. Protein phosphatase 1gamma is responsible for dephosphorylation of histone H3 at Thr 11 after DNA damage. EMBO Rep 2010; 11:883-9.
-
(2010)
EMBO Rep
, vol.11
, pp. 883-889
-
-
Shimada, M.1
Haruta, M.2
Niida, H.3
Sawamoto, K.4
Nakanishi, M.5
-
112
-
-
4644303544
-
Resisting arrest: Recovery from checkpoint arrest through dephosphorylation of Chk1 by PP1
-
den EN, Kosoy A, Christopoulos H, O'Connell MJ. Resisting arrest: recovery from checkpoint arrest through dephosphorylation of Chk1 by PP1. Cell Cycle 2004; 3:529-33. (Pubitemid 40278178)
-
(2004)
Cell Cycle
, vol.3
, Issue.5
, pp. 529-533
-
-
Den, E.N.1
Kosoy, A.2
Christopoulos, H.3
O'Connell, M.J.4
-
113
-
-
33846203708
-
ATM regulates ionizing radiation-induced disruption of HDAC1:PP1:Rb complexes
-
DOI 10.1016/j.cellsig.2006.08.001, PII S0898656806001938
-
Guo C, Mi J, Brautigan DL, Larner JM. ATM regulates ionizing radiation-induced disruption of HDAC1:PP1:Rb complexes. Cell Signal 2007; 19:504-10. (Pubitemid 46107801)
-
(2007)
Cellular Signalling
, vol.19
, Issue.3
, pp. 504-510
-
-
Guo, C.1
Mi, J.2
Brautigan, D.L.3
Larner, J.M.4
-
114
-
-
78149464883
-
Serine/threonine phosphatases in the DNA damage response and cancer
-
Peng A, Maller JL. Serine/threonine phosphatases in the DNA damage response and cancer. Oncogene 2010; 29:5977-88.
-
(2010)
Oncogene
, vol.29
, pp. 5977-5988
-
-
Peng, A.1
Maller, J.L.2
-
115
-
-
0346274978
-
KRAB-containing zinc-finger repressor proteins
-
Urrutia R. KRAB-containing zinc-finger repressor proteins. Genome Biol 2003; 4:231.
-
(2003)
Genome Biol
, vol.4
, pp. 231
-
-
Urrutia, R.1
|