메뉴 건너뛰기




Volumn 349, Issue 2, 2000, Pages 509-518

NIMA-related kinase 2 (Nek2), a cell-cycle-regulated protein kinase localized to centrosomes, is complexed to protein phosphatase 1

Author keywords

Cell signalling; Centrosome; NIMA related kinase; Protein serine threonine phosphatase

Indexed keywords

CELL CYCLE PROTEIN; CELL EXTRACT; ENZYME INHIBITOR; N METHYL DEXTRO ASPARTIC ACID; PHOSPHOPROTEIN PHOSPHATASE 1; PROTEIN KINASE; PROTEIN SERINE KINASE; THREONINE;

EID: 0034661499     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3490509     Document Type: Article
Times cited : (168)

References (47)
  • 1
    • 0024397415 scopus 로고
    • The structure and regulation of protein phosphatases
    • 1 Cohen, P. (1989) The structure and regulation of protein phosphatases. Annu. Rev. Biochem. 58, 453-508
    • (1989) Annu. Rev. Biochem. , vol.58 , pp. 453-508
    • Cohen, P.1
  • 2
    • 0026695872 scopus 로고
    • The structure, role and regulation of type I protein phosphatases
    • 2 Bollen, M and Stalmans, W. (1992) The structure, role and regulation of type I protein phosphatases. Crit. Rev. Biochem. Mol. Biol. 27, 227-281
    • (1992) Crit. Rev. Biochem. Mol. Biol. , vol.27 , pp. 227-281
    • Bollen, M.1    Stalmans, W.2
  • 3
    • 0027277098 scopus 로고
    • On target with a new mechanism for the regulation of protein phosphorylation
    • 3 Hubbard, M. J. and Cohen, P. (1993) On target with a new mechanism for the regulation of protein phosphorylation. Trends Biochem. Sci. 18, 172-177
    • (1993) Trends Biochem. Sci. , vol.18 , pp. 172-177
    • Hubbard, M.J.1    Cohen, P.2
  • 4
    • 0030036564 scopus 로고    scopus 로고
    • Identification of the protein phosphatase-1-binding domains on the glycogen and myofibrillar targetting subunits
    • 4 Johnson, D. F., Moorhead, G., Caudwell, F. B., Cohen, P., Chen, Y. H., Chen, M. X. and Cohen, P. T. W. (1996) Identification of the protein phosphatase-1-binding domains on the glycogen and myofibrillar targetting subunits. Eur. J. Biochem. 239, 317-325
    • (1996) Eur. J. Biochem. , vol.239 , pp. 317-325
    • Johnson, D.F.1    Moorhead, G.2    Caudwell, F.B.3    Cohen, P.4    Chen, Y.H.5    Chen, M.X.6    Cohen, P.T.W.7
  • 6
    • 0032994412 scopus 로고    scopus 로고
    • Nuclear organisation of NIPP1, a regulatory subunit of protein phosphatase 1 that assocoiates with pre-mRNA splicing factors
    • 6 Trinkle-Mulcahy, L., Ajuh, P., Prescott, A., Claverie-Martin, F., Cohen, S., Lamond, A. I. and Cohen, P. (1999) Nuclear organisation of NIPP1, a regulatory subunit of protein phosphatase 1 that assocoiates with pre-mRNA splicing factors. J. Cell Sci. 112, 157-168
    • (1999) J. Cell Sci. , vol.112 , pp. 157-168
    • Trinkle-Mulcahy, L.1    Ajuh, P.2    Prescott, A.3    Claverie-Martin, F.4    Cohen, S.5    Lamond, A.I.6    Cohen, P.7
  • 7
    • 0031583952 scopus 로고    scopus 로고
    • Purification and characterisation of p99, a nuclear modulator of protein phosphatase 1 activity
    • 7 Kreivi, J.-P., Trinkle-Mulcahy, L., Lyon, C. E., Morrice, N. A., Cohen, P. and Lamond, A. I. (1997) Purification and characterisation of p99, a nuclear modulator of protein phosphatase 1 activity FEBS Lett. 420, 57-62
    • (1997) FEBS Lett. , vol.420 , pp. 57-62
    • Kreivi, J.-P.1    Trinkle-Mulcahy, L.2    Lyon, C.E.3    Morrice, N.A.4    Cohen, P.5    Lamond, A.I.6
  • 8
    • 0032512720 scopus 로고    scopus 로고
    • Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit
    • 8 Allen, P. B., Kwon, Y.-G., Nairn, A. C. and Greengard, P. (1998) Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit. Proc. Natl Acad. Sci. U.S.A. 273, 4089-4095
    • (1998) Proc. Natl Acad. Sci. U.S.A. , vol.273 , pp. 4089-4095
    • Allen, P.B.1    Kwon, Y.-G.2    Nairn, A.C.3    Greengard, P.4
  • 9
    • 0030199521 scopus 로고    scopus 로고
    • Interaction of protein phosphatase type 1 with a splicing factor
    • 9 Hirano, K., Erdödi, F., Patton, J. G. and Hartshorne, D. J. (1996) Interaction of protein phosphatase type 1 with a splicing factor. FEBS Lett. 389, 191-194
    • (1996) FEBS Lett. , vol.389 , pp. 191-194
    • Hirano, K.1    Erdödi, F.2    Patton, J.G.3    Hartshorne, D.J.4
  • 10
    • 0002023634 scopus 로고
    • Mitotic regulation of protein phosphatases by the fission yeast sds22 protein
    • 10 Stone, E. M., Yamano, H., Kinoshita, N. and Yanagida, M. (1993) Mitotic regulation of protein phosphatases by the fission yeast sds22 protein. Curr. Biol. 3, 13-26
    • (1993) Curr. Biol. , vol.3 , pp. 13-26
    • Stone, E.M.1    Yamano, H.2    Kinoshita, N.3    Yanagida, M.4
  • 13
    • 0029617851 scopus 로고
    • Protein phosphatase 1 interacts with p53BP2, a protein which binds to the tumour suppressor p53
    • 13 Helps, N. R., Barker, H. M., Elledge, S. J. and Cohen, P. T. W. (1995) Protein phosphatase 1 interacts with p53BP2, a protein which binds to the tumour suppressor p53. FEBS Lett. 377, 295-300
    • (1995) FEBS Lett. , vol.377 , pp. 295-300
    • Helps, N.R.1    Barker, H.M.2    Elledge, S.J.3    Cohen, P.T.W.4
  • 14
    • 0029896654 scopus 로고    scopus 로고
    • Characterisation of a ribosomal inhibitory polypeptide of protein phosphatase-1 from rat liver
    • 14 Buellens, M., Stalmans, W. and Bollen, M. (1996) Characterisation of a ribosomal inhibitory polypeptide of protein phosphatase-1 from rat liver. Eur. J. Biochem. 239, 183-189
    • (1996) Eur. J. Biochem. , vol.239 , pp. 183-189
    • Buellens, M.1    Stalmans, W.2    Bollen, M.3
  • 15
    • 0031017382 scopus 로고    scopus 로고
    • 134.5 protein of herpes simplex virus 1 complexes to protein phosphatase 1α to dephosphorylate the a subunit of eukaryotic translation initiation factor 2 and preclude the shut of protein synthesis by double stranded RNA-activated protein kinase
    • 134.5 protein of herpes simplex virus 1 complexes to protein phosphatase 1α to dephosphorylate the a subunit of eukaryotic translation initiation factor 2 and preclude the shut of protein synthesis by double stranded RNA-activated protein kinase. Proc. Natl. Acad. Sci. U.SA. 94, 843-848
    • (1997) Proc. Natl. Acad. Sci. U.S A. , vol.94 , pp. 843-848
    • He, B.1    Gross, M.2    Roizman, B.3
  • 16
    • 0029129557 scopus 로고
    • Serine/threonine protein phosphatases
    • 16 Wera, S. and Hemmings, B. A. (1995) Serine/threonine protein phosphatases. Biochem. J. 311, 17-29
    • (1995) Biochem. J. , vol.311 , pp. 17-29
    • Wera, S.1    Hemmings, B.A.2
  • 17
    • 0030977268 scopus 로고    scopus 로고
    • Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1
    • 17 Egloff, M.-P., Johnson, F., Moorhead, G., Cohen, P. T. W., Cohen, P. and Barford, D. (1997) Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1. EMBO J 16, 1876-1887
    • (1997) EMBO J , vol.16 , pp. 1876-1887
    • Egloff, M.-P.1    Johnson, F.2    Moorhead, G.3    Cohen, P.T.W.4    Cohen, P.5    Barford, D.6
  • 18
    • 0029385296 scopus 로고
    • The NIMA kinase joins forces with Cdc2
    • 18 Fry, A. M. and Nigg, E. A. (1995) The NIMA kinase joins forces with Cdc2. Curr. Biol. 5, 1122-1125
    • (1995) Curr. Biol. , vol.5 , pp. 1122-1125
    • Fry, A.M.1    Nigg, E.A.2
  • 19
    • 0029418210 scopus 로고
    • The NIMA kinase: A mitotic regulator in Aspergillus nidulans and vertebrate cells
    • Meijer, L., Guidel, S. and Tung, H. Y. L., eds., Plenum Press, New York
    • 19 Lu, K. P. and Hunter, T. (1995) The NIMA kinase: a mitotic regulator in Aspergillus nidulans and vertebrate cells. In Progress in Cell Cycle Research , vol. 1 (Meijer, L., Guidel, S. and Tung, H. Y. L., eds.), pp. 187-205, Plenum Press, New York
    • (1995) Progress in Cell Cycle Research , vol.1 , pp. 187-205
    • Lu, K.P.1    Hunter, T.2
  • 20
    • 0029843956 scopus 로고    scopus 로고
    • Cell cycle regulation in Aspergillus by two protein kinases
    • 20 Osmani, S. A. and Ye, X. S. (1996) Cell cycle regulation in Aspergillus by two protein kinases. Biochem. J. 317, 633-641
    • (1996) Biochem. J. , vol.317 , pp. 633-641
    • Osmani, S.A.1    Ye, X.S.2
  • 21
    • 0020622867 scopus 로고
    • A mutation in Aspergillus nidulans that blocks the transition trom interphase to prophase
    • 21 Oakley, B. R. and Morris, N. R. (1983) A mutation in Aspergillus nidulans that blocks the transition trom interphase to prophase J. Cell Biol. 96, 1155-1158
    • (1983) J. Cell Biol. , vol.96 , pp. 1155-1158
    • Oakley, B.R.1    Morris, N.R.2
  • 22
    • 0026048594 scopus 로고
    • Parallel activation of the NIMA and p34cdc2 cell cycle-regulated protein kinases is required to initiate mitosis in A. nidulans
    • 22 Osmani, A. H., McGuire, S. L. and Osmani, S. A. (1991) Parallel activation of the NIMA and p34cdc2 cell cycle-regulated protein kinases is required to initiate mitosis in A. nidulans. Cell 67, 283-291
    • (1991) Cell , vol.67 , pp. 283-291
    • Osmani, A.H.1    McGuire, S.L.2    Osmani, S.A.3
  • 23
    • 0028904124 scopus 로고
    • The NIMA protein kinase is hyperphosphorylated and activated downstream of p34cdc2/cyclinB: Coordination of two mitosis promoting kinases
    • 23 Ye, X. S., Xu, G., Pu, R. T., Fincher, R. R., McGuire, S. L., Osmani, A. H. and Osmani, S. A. (1995) The NIMA protein kinase is hyperphosphorylated and activated downstream of p34cdc2/cyclinB: coordination of two mitosis promoting kinases. EMBO J. 14, 986-994
    • (1995) EMBO J. , vol.14 , pp. 986-994
    • Ye, X.S.1    Xu, G.2    Pu, R.T.3    Fincher, R.R.4    McGuire, S.L.5    Osmani, A.H.6    Osmani, S.A.7
  • 24
    • 0029028584 scopus 로고
    • Evidence for a NIMA-like mitotic pathway in vertebrate cells
    • 24 Lu, K. P. and Hunter, T. (1995) Evidence for a NIMA-like mitotic pathway in vertebrate cells. Cell 81, 413-424
    • (1995) Cell , vol.81 , pp. 413-424
    • Lu, K.P.1    Hunter, T.2
  • 25
    • 0028058885 scopus 로고
    • Cell cycle-dependent expression of Nek2, a novel human protein kinase related to the NIMA mitotic regulator of Aspergillus nidulans
    • 25 Schultz, S. J., Fry, A. M., Sütterlin, C., Ried, T. and Nigg, E. A. (1994) Cell cycle-dependent expression of Nek2, a novel human protein kinase related to the NIMA mitotic regulator of Aspergillus nidulans. Cell Growth Differ. 5, 625-635
    • (1994) Cell Growth Differ. , vol.5 , pp. 625-635
    • Schultz, S.J.1    Fry, A.M.2    Sütterlin, C.3    Ried, T.4    Nigg, E.A.5
  • 26
    • 0029011885 scopus 로고
    • Substrate specificity and cell cycle regulation of the Nek2 protein kinase, a potential human homologue of the mitotic regulator NIMA of Aspergillus nidulans
    • 26 Fry, A. M., Scultz, S. J., Bartek, J. and Nigg, E. A. (1995) Substrate specificity and cell cycle regulation of the Nek2 protein kinase, a potential human homologue of the mitotic regulator NIMA of Aspergillus nidulans. J. Biol. Chem. 270, 12899-12905
    • (1995) J. Biol. Chem. , vol.270 , pp. 12899-12905
    • Fry, A.M.1    Scultz, S.J.2    Bartek, J.3    Nigg, E.A.4
  • 27
    • 0032518798 scopus 로고    scopus 로고
    • A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators
    • 27 Fry, A. M., Meraldi, P. and Nigg, E. A. (1998) A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators. EMBO J. 17, 470-481
    • (1998) EMBO J. , vol.17 , pp. 470-481
    • Fry, A.M.1    Meraldi, P.2    Nigg, E.A.3
  • 28
    • 0032578008 scopus 로고    scopus 로고
    • C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2
    • 28 Fry, A. M., Mayor, T., Meraldi, P., Stierhof, Y.-D., Tanaka, K. and Nigg, E. A. (1998) C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2. J. Cell Biol. 141, 1563-1574
    • (1998) J. Cell Biol. , vol.141 , pp. 1563-1574
    • Fry, A.M.1    Mayor, T.2    Meraldi, P.3    Stierhof, Y.-D.4    Tanaka, K.5    Nigg, E.A.6
  • 29
    • 0028347434 scopus 로고
    • Cloning of the complete coding region for human protein phosphatase inhibitor 2 using the two hybrid system and expression of inhibitor 2 in E. coli
    • 29 Helps, N. R., Street, A. J., Elledge, S. J. and Cohen, P. T. W. (1994) Cloning of the complete coding region for human protein phosphatase inhibitor 2 using the two hybrid system and expression of inhibitor 2 in E. coli. FEBS Lett. 340, 93-98
    • (1994) FEBS Lett. , vol.340 , pp. 93-98
    • Helps, N.R.1    Street, A.J.2    Elledge, S.J.3    Cohen, P.T.W.4
  • 31
    • 0001823786 scopus 로고
    • Recombinant PCR
    • Innis, M. A., Gelfand, D. H., Sninsky, J. J. and White, T. J., eds. Academic Press, San Diego
    • 31 Higuchi, R. (1990) Recombinant PCR. In PCR Protocols, a Guide to Methods and Applications (Innis, M. A., Gelfand, D. H., Sninsky, J. J. and White, T. J., eds.), pp 177-183, Academic Press, San Diego
    • (1990) PCR Protocols, A Guide to Methods and Applications , pp. 177-183
    • Higuchi, R.1
  • 32
    • 0029088182 scopus 로고
    • The cyanobacterial toxin microcystin binds covalently to cysteine-273 on protein phosphatase 1
    • 32 MacKintosh, R. W., Dalby, K. N., Campbell, D. G., Cohen, P. T W., Cohen, P. and MacKintosh, C. (1995) The cyanobacterial toxin microcystin binds covalently to cysteine-273 on protein phosphatase 1. FEBS Lett. 371, 236-240
    • (1995) FEBS Lett. , vol.371 , pp. 236-240
    • MacKintosh, R.W.1    Dalby, K.N.2    Campbell, D.G.3    Cohen, P.T.W.4    Cohen, P.5    MacKintosh, C.6
  • 33
    • 0027171705 scopus 로고
    • Sequence of human protein serine/threonine phosphatase 1 gamma and localization of the gene (PPP1CC) encoding it to chromosome bands 12q24.1-q242
    • 33 Barker, H. M., Craig, S. P., Spurr, N. K. and Cohen, P. T. W. (1993) Sequence of human protein serine/threonine phosphatase 1 gamma and localization of the gene (PPP1CC) encoding it to chromosome bands 12q24.1-q242. Biochim. Biophys. Acta 1178, 228-233
    • (1993) Biochim. Biophys. Acta , vol.1178 , pp. 228-233
    • Barker, H.M.1    Craig, S.P.2    Spurr, N.K.3    Cohen, P.T.W.4
  • 34
    • 0027233603 scopus 로고
    • Inhibitor-2 functions like a chaperone to fold three expressed isoforms of mammalian protein phosphatase-1 into a conformation with the specificity and regulatory properties of the native enzyme
    • 34 Alessi, D. R., Street, A. J., Cohen, P. and Cohen, P. T. W. (1993) Inhibitor-2 functions like a chaperone to fold three expressed isoforms of mammalian protein phosphatase-1 into a conformation with the specificity and regulatory properties of the native enzyme. Eur. J. Biochem. 213, 1055-1066
    • (1993) Eur. J. Biochem. , vol.213 , pp. 1055-1066
    • Alessi, D.R.1    Street, A.J.2    Cohen, P.3    Cohen, P.T.W.4
  • 35
    • 0002547043 scopus 로고
    • Immunoaffinity purification
    • Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • 35 Harlow, E. and Lane, D. (1988) Immunoaffinity purification. In Antibodies: a Laboratory Manual, pp 511-552, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • (1988) Antibodies: A Laboratory Manual , pp. 511-552
    • Harlow, E.1    Lane, D.2
  • 38
    • 0001057395 scopus 로고
    • Assay and purification ot protein (serine/threonine) phosphatases
    • Hardie, D. G., ed, IRL Press, Oxford
    • 38 MacKintosh, C. (1993) Assay and purification ot protein (serine/threonine) phosphatases. In Protein Phosphorylation, a Practical Approach (Hardie, D. G., ed), pp. 197-230, IRL Press, Oxford
    • (1993) Protein Phosphorylation, A Practical Approach , pp. 197-230
    • MacKintosh, C.1
  • 40
    • 0029583122 scopus 로고
    • Crystal structure of the catalytic subunit of human protein phosphalase 1 and its complex with tungstate
    • 40 Egloff, M.-P., Cohen, P. T. W., Reinemer, P. and Barford, D. (1995) Crystal structure of the catalytic subunit of human protein phosphalase 1 and its complex with tungstate. J. Mol. Biol. 254, 942-959
    • (1995) J. Mol. Biol. , vol.254 , pp. 942-959
    • Egloff, M.-P.1    Cohen, P.T.W.2    Reinemer, P.3    Barford, D.4
  • 41
    • 0032101295 scopus 로고    scopus 로고
    • Differential subcellular localization of protein phosphatase-1 alpha, gamma1 and delta isoforms during both interphase and mitosis in mammalian cells
    • 41 Andreassen, P. R., Lacroix, F. B., Villa-Moruzzi, E. and Margolis, R. L. (1998) Differential subcellular localization of protein phosphatase-1 alpha, gamma1 and delta isoforms during both interphase and mitosis in mammalian cells. J. Cell Biol. 141, 1207-1215
    • (1998) J. Cell Biol. , vol.141 , pp. 1207-1215
    • Andreassen, P.R.1    Lacroix, F.B.2    Villa-Moruzzi, E.3    Margolis, R.L.4
  • 45
    • 12644291188 scopus 로고    scopus 로고
    • Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase
    • 45 Kwon, Y.-G., Lee, S. Y., Choi, Y., Greengard, P. and Nairn, A. C. (1997) Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase. Proc. Natl. Acad. Sci. U.S.A. 94, 2168-2173
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 2168-2173
    • Kwon, Y.-G.1    Lee, S.Y.2    Choi, Y.3    Greengard, P.4    Nairn, A.C.5
  • 46
    • 0031081209 scopus 로고    scopus 로고
    • Cell-cycle control: POLO-like kinases join the outer circle
    • 46 Lane, H. A. and Nigg, E. A. (1997) Cell-cycle control: POLO-like kinases join the outer circle. Trends Cell Biol. 7, 63-68
    • (1997) Trends Cell Biol. , vol.7 , pp. 63-68
    • Lane, H.A.1    Nigg, E.A.2
  • 47
    • 0034678923 scopus 로고    scopus 로고
    • Nek2B, a novel maternal form of Nek2 kinase, is essential for the assembly or maintenance of centrosomes in early Xenopus embryos
    • 47 Uto, K. and Sagata, N. (2000) Nek2B, a novel maternal form of Nek2 kinase, is essential for the assembly or maintenance of centrosomes in early Xenopus embryos EMBO J. 19, 1816-1826
    • (2000) EMBO J. , vol.19 , pp. 1816-1826
    • Uto, K.1    Sagata, N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.