Phosphatase inhibition and cell survival after DNA damage induced by radiation

Cancer Biology and Therapy

Volumn 8, Issue 16, 2009, Pages 1577-1586

  Hamilton, Julie ^a   Grawenda, Anna M ^a   Bernhard, Eric J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Calyculin A; Okadaic acid; PHLPP; PHLPPL; Phosphorylation; PP1; PP2A; Radiosensitivity

Indexed keywords

CALYCULIN A; EPIDERMAL GROWTH FACTOR RECEPTOR; GAMMA HISTONE H2AX; HISTONE H2AX; K RAS PROTEIN; OKADAIC ACID; PH DOMAIN AND LEUCINE RICH REPEAT PROTEIN PHOSPHATASE; PH DOMAIN AND LEUCINE RICH REPEAT PROTEIN PHOSPHATASE LIKE; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN KINASE B; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; DNA; NUCLEAR PROTEIN; OXAZOLE DERIVATIVE; PHLPP PROTEIN, HUMAN;

ARTICLE; CELL CYCLE; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MUTATIONAL ANALYSIS; ONCOGENE H RAS; ONCOGENE N RAS; PROTEIN EXPRESSION; RADIOSENSITIVITY; SENSITIZATION; DRUG ANTAGONISM; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; METABOLISM; PHOSPHORYLATION; RADIATION DOSE; RADIATION EXPOSURE; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

CELL LINE, TUMOR; DNA DAMAGE; DNA, NEOPLASM; HUMANS; NUCLEAR PROTEINS; OKADAIC ACID; OXAZOLES; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RADIATION TOLERANCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 70349122544     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.8.16.8962     Document Type: Article

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