-
1
-
-
0021686169
-
Dynamic instability of microtubule growth
-
DOI 10.1038/312237a0
-
T. Mitchison, and M. Kirschner Dynamic instability of microtubule growth Nature 312 1984 237 242 (Pubitemid 15201998)
-
(1984)
Nature
, vol.312
, Issue.5991
, pp. 237-242
-
-
Mitchinson, T.1
Kirschner, M.2
-
2
-
-
34548436228
-
Targeting microtubules to inhibit angiogenesis and disrupt tumour vasculature: Implications for cancer treatment
-
DOI 10.2174/156800907781662266
-
E. Pasquier, N. Andre, and D. Braguer Targeting microtubules to inhibit angiogenesis and disrupt tumour vasculature: implications for cancer treatment Curr. Cancer Drug Targets 7 2007 566 581 (Pubitemid 47358143)
-
(2007)
Current Cancer Drug Targets
, vol.7
, Issue.6
, pp. 566-581
-
-
Pasquier, E.1
Andre, N.2
Braguer, D.3
-
3
-
-
77950608347
-
Microtubule targeting agents: From biophysics to proteomics
-
D. Calligaris, P. Verdier-Pinard, F. Devred, C. Villard, D. Braguer, and D. Lafitte Microtubule targeting agents: from biophysics to proteomics Cell. Mol. Life Sci. 67 2010 1089 1104
-
(2010)
Cell. Mol. Life Sci.
, vol.67
, pp. 1089-1104
-
-
Calligaris, D.1
Verdier-Pinard, P.2
Devred, F.3
Villard, C.4
Braguer, D.5
Lafitte, D.6
-
5
-
-
77952168147
-
Targeted delivery for breast cancer therapy: The history of nanoparticle-albumin-bound paclitaxel
-
F. Petrelli, K. Borgonovo, and S. Barni Targeted delivery for breast cancer therapy: the history of nanoparticle-albumin-bound paclitaxel Expert Opin. Pharmacother. 11 2010 1413 1432
-
(2010)
Expert Opin. Pharmacother.
, vol.11
, pp. 1413-1432
-
-
Petrelli, F.1
Borgonovo, K.2
Barni, S.3
-
6
-
-
68849087436
-
Microtubule inhibitors: Differentiating tubulin-inhibiting agents based on mechanisms of action, clinical activity, and resistance
-
E.A. Perez Microtubule inhibitors: differentiating tubulin-inhibiting agents based on mechanisms of action, clinical activity, and resistance Mol. Cancer Ther. 8 2009 2086 2095
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 2086-2095
-
-
Perez, E.A.1
-
7
-
-
11244309692
-
New microtubule/tubulin-targeted anticancer drugs and novel chemotherapeutic strategies
-
L. Wilson, and M.A. Jordan New microtubule/tubulin-targeted anticancer drugs and novel chemotherapeutic strategies J. Chemother. 16 Suppl 4 2004 83 85 (Pubitemid 40065290)
-
(2004)
Journal of Chemotherapy
, vol.16
, Issue.SUPPL. 4
, pp. 83-85
-
-
Wilson, L.1
Jordan, M.A.2
-
8
-
-
1942490811
-
Suppression of microtubule dynamics by discodermolide by a novel mechanism is associated with mitotic arrest and inhibition of tumor cell proliferation
-
S. Honore, K. Kamath, D. Braguer, L. Wilson, C. Briand, and M.A. Jordan Suppression of microtubule dynamics by discodermolide by a novel mechanism is associated with mitotic arrest and inhibition of tumor cell proliferation Mol. Cancer Ther. 2 2003 1303 1311
-
(2003)
Mol. Cancer Ther.
, vol.2
, pp. 1303-1311
-
-
Honore, S.1
Kamath, K.2
Braguer, D.3
Wilson, L.4
Briand, C.5
Jordan, M.A.6
-
9
-
-
29344471072
-
Understanding microtubule dynamics for improved cancer therapy
-
DOI 10.1007/s00018-005-5330-x
-
S. Honore, E. Pasquier, and D. Braguer Understanding microtubule dynamics for improved cancer therapy Cell. Mol. Life Sci. 62 2005 3039 3056 (Pubitemid 43004753)
-
(2005)
Cellular and Molecular Life Sciences
, vol.62
, Issue.24
, pp. 3039-3056
-
-
Honore, S.1
Pasquier, E.2
Braguer, D.3
-
10
-
-
0141507953
-
Suppression of microtubule dynamics by epothilone B is associated with mitotic arrest
-
K. Kamath, and M.A. Jordan Suppression of microtubule dynamics by epothilone B is associated with mitotic arrest Cancer Res. 63 2003 6026 6031 (Pubitemid 37187506)
-
(2003)
Cancer Research
, vol.63
, Issue.18
, pp. 6026-6031
-
-
Kamath, K.1
Jordan, M.A.2
-
11
-
-
33645533966
-
Antiangiogenic concentrations of vinflunine increase the interphase microtubule dynamics and decrease the motility of endothelial cells
-
B. Pourroy, S. Honore, E. Pasquier, V. Bourgarel-Rey, A. Kruczynski, C. Briand, and D. Braguer Antiangiogenic concentrations of vinflunine increase the interphase microtubule dynamics and decrease the motility of endothelial cells Cancer Res. 66 2006 3256 3263
-
(2006)
Cancer Res.
, vol.66
, pp. 3256-3263
-
-
Pourroy, B.1
Honore, S.2
Pasquier, E.3
Bourgarel-Rey, V.4
Kruczynski, A.5
Briand, C.6
Braguer, D.7
-
12
-
-
7744233719
-
Stuck in division or passing through: What happens when cells cannot satisfy the spindle assembly checkpoint
-
DOI 10.1016/j.devcel.2004.09.002, PII S1534580704003016
-
C.L. Rieder, and H. Maiato Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint Dev. Cell 7 2004 637 651 (Pubitemid 39462685)
-
(2004)
Developmental Cell
, vol.7
, Issue.5
, pp. 637-651
-
-
Rieder, C.L.1
Maiato, H.2
-
13
-
-
3142723291
-
Synergistic suppression of microtubule dynamics by discodermolide and paclitaxel in non-small cell lung carcinoma cells
-
DOI 10.1158/0008-5472.CAN-04-0693
-
S. Honore, K. Kamath, D. Braguer, S.B. Horwitz, L. Wilson, C. Briand, and M.A. Jordan Synergistic suppression of microtubule dynamics by discodermolide and paclitaxel in non-small cell lung carcinoma cells Cancer Res. 64 2004 4957 4964 (Pubitemid 38924543)
-
(2004)
Cancer Research
, vol.64
, Issue.14
, pp. 4957-4964
-
-
Honore, S.1
Kamath, K.2
Braguer, D.3
Horwitz, S.B.4
Wilson, L.5
Briand, C.6
Jordan, M.A.7
-
14
-
-
0034960408
-
Mechanism of mitotic block and inhibition of cell proliferation by the semisynthetic Vinca alkaloids vinorelbine and its newer derivative vinflunine
-
V.K. Ngan, K. Bellman, B.T. Hill, L. Wilson, and M.A. Jordan Mechanism of mitotic block and inhibition of cell proliferation by the semisynthetic Vinca alkaloids vinorelbine and its newer derivative vinflunine Mol. Pharmacol. 60 2001 225 232 (Pubitemid 32595250)
-
(2001)
Molecular Pharmacology
, vol.60
, Issue.1
, pp. 225-232
-
-
Ngan, V.K.1
Bellman, K.2
Hill, B.T.3
Wilson, L.4
Jordan, M.A.5
-
15
-
-
4944234717
-
1 arrest and a mitochondrial pathway
-
B. Pourroy, M. Carre, S. Honore, V. Bourgarel-Rey, A. Kruczynski, C. Briand, and D. Braguer Low concentrations of vinflunine induce apoptosis in human SK-N-SH neuroblastoma cells through a postmitotic G1 arrest and a mitochondrial pathway Mol. Pharmacol. 66 2004 580 591 (Pubitemid 39329257)
-
(2004)
Molecular Pharmacology
, vol.66
, Issue.3
, pp. 580-591
-
-
Pourroy, B.1
Carre, M.2
Honore, S.3
Bourgarel-Rey, V.4
Kruczynski, A.5
Briand, C.6
Braguer, D.7
-
16
-
-
67649362238
-
Length of mitotic arrest induced by microtubule-stabilizing drugs determines cell death after mitotic exit
-
M.E. Bekier, R. Fischbach, J. Lee, and W.R. Taylor Length of mitotic arrest induced by microtubule-stabilizing drugs determines cell death after mitotic exit Mol. Cancer Ther. 8 2009 1646 1654
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 1646-1654
-
-
Bekier, M.E.1
Fischbach, R.2
Lee, J.3
Taylor, W.R.4
-
17
-
-
33845228689
-
Bcl-2 down-regulation and tubulin subtype composition are involved in resistance of ovarian cancer cells to vinflunine
-
DOI 10.1158/1535-7163.MCT-06-0277
-
M.A. Esteve, M. Carre, V. Bourgarel-Rey, A. Kruczynski, G. Raspaglio, C. Ferlini, and D. Braguer Bcl-2 down-regulation and tubulin subtype composition are involved in resistance of ovarian cancer cells to vinflunine Mol. Cancer Ther. 5 2006 2824 2833 (Pubitemid 44849009)
-
(2006)
Molecular Cancer Therapeutics
, vol.5
, Issue.11
, pp. 2824-2833
-
-
Esteve, M.-A.1
Carre, M.2
Bourgarel-Rey, V.3
Kruczynski, A.4
Raspaglio, G.5
Ferlini, C.6
Braguer, D.7
-
18
-
-
0028857104
-
Low concentrations of nocodazole interfere with fibroblast locomotion without significantly affecting microtubule level: Implications for the role of dynamic microtubules in cell locomotion
-
G. Liao, T. Nagasaki, and G.G. Gundersen Low concentrations of nocodazole interfere with fibroblast locomotion without significantly affecting microtubule level: implications for the role of dynamic microtubules in cell locomotion J. Cell Sci. 108 Pt 11 1995 3473 3483
-
(1995)
J. Cell Sci.
, vol.108
, Issue.PART 11
, pp. 3473-3483
-
-
Liao, G.1
Nagasaki, T.2
Gundersen, G.G.3
-
19
-
-
0032451018
-
Relationship between microtubule dynamics and lamellipodium formation revealed by direct imaging of microtubules in cells treated with nocodazole or taxol
-
DOI 10.1002/(SICI)1097-0169(1998)41:4<325::AID-CM5>3.0.CO;2-D
-
A. Mikhailov, and G.G. Gundersen Relationship between microtubule dynamics and lamellipodium formation revealed by direct imaging of microtubules in cells treated with nocodazole or taxol Cell Motil. Cytoskeleton 41 1998 325 340 (Pubitemid 29086468)
-
(1998)
Cell Motility and the Cytoskeleton
, vol.41
, Issue.4
, pp. 325-340
-
-
Mikhailov, A.1
Gundersen, G.G.2
-
20
-
-
16844381714
-
Antiangiogenic concentrations of paclitaxel induce an increase in microtubule dynamics in endothelial cells but not in cancer cells
-
DOI 10.1158/0008-5472.CAN-04-2624
-
E. Pasquier, S. Honore, B. Pourroy, M.A. Jordan, M. Lehmann, C. Briand, and D. Braguer Antiangiogenic concentrations of paclitaxel induce an increase in microtubule dynamics in endothelial cells but not in cancer cells Cancer Res. 65 2005 2433 2440 (Pubitemid 40490155)
-
(2005)
Cancer Research
, vol.65
, Issue.6
, pp. 2433-2440
-
-
Pasquier, E.1
Honore, S.2
Pourroy, B.3
Jordan, M.A.4
Lehmann, M.5
Briand, C.6
Braguer, D.7
-
21
-
-
51049105074
-
Antiangiogenic vinflunine affects EB1 localization and microtubule targeting to adhesion sites
-
S. Honore, A. Pagano, G. Gauthier, V. Bourgarel-Rey, P. Verdier-Pinard, K. Civiletti, A. Kruczynski, and D. Braguer Antiangiogenic vinflunine affects EB1 localization and microtubule targeting to adhesion sites Mol. Cancer Ther. 7 2008 2080 2089
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 2080-2089
-
-
Honore, S.1
Pagano, A.2
Gauthier, G.3
Bourgarel-Rey, V.4
Verdier-Pinard, P.5
Civiletti, K.6
Kruczynski, A.7
Braguer, D.8
-
22
-
-
41149156427
-
Tracking the ends: A dynamic protein network controls the fate of microtubule tips
-
DOI 10.1038/nrm2369, PII NRM2369
-
A. Akhmanova, and M.O. Steinmetz Tracking the ends: a dynamic protein network controls the fate of microtubule tips Nat. Rev. Mol. Cell Biol. 9 2008 309 322 (Pubitemid 351430849)
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
, Issue.4
, pp. 309-322
-
-
Akhmanova, A.1
Steinmetz, M.O.2
-
23
-
-
77954762893
-
Olesoxime prevents microtubule-targeting drug neurotoxicity: Selective preservation of EB comets in differentiated neuronal cells
-
A. Rovini, M. Carre, T. Bordet, R.M. Pruss, and D. Braguer Olesoxime prevents microtubule-targeting drug neurotoxicity: selective preservation of EB comets in differentiated neuronal cells Biochem. Pharmacol. 80 2010 884 894
-
(2010)
Biochem. Pharmacol.
, vol.80
, pp. 884-894
-
-
Rovini, A.1
Carre, M.2
Bordet, T.3
Pruss, R.M.4
Braguer, D.5
-
24
-
-
33744785404
-
Novel combretastatin analogues endowed with antitumor activity
-
DOI 10.1021/jm0510732
-
D. Simoni, R. Romagnoli, R. Baruchello, R. Rondanin, M. Rizzi, M.G. Pavani, D. Alloatti, G. Giannini, M. Marcellini, T. Riccioni, M. Castorina, M.B. Guglielmi, F. Bucci, P. Carminati, and C. Pisano Novel combretastatin analogues endowed with antitumor activity J. Med. Chem. 49 2006 3143 3152 (Pubitemid 43830513)
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.11
, pp. 3143-3152
-
-
Simoni, D.1
Romagnoli, R.2
Baruchello, R.3
Rondanin, R.4
Rizzi, M.5
Pavani, M.G.6
Alloatti, D.7
Giannini, G.8
Marcellini, M.9
Riccioni, T.10
Castorina, M.11
Guglielmi, M.B.12
Bucci, F.13
Carminati, P.14
Pisano, C.15
-
25
-
-
23044482259
-
Investigation of antitumor effects of synthetic epothilone analogs in human myeloma models in vitro and in vivo
-
DOI 10.1073/pnas.0504512102
-
K.D. Wu, Y.S. Cho, J. Katz, V. Ponomarev, S. Chen-Kiang, S.J. Danishefsky, and M.A. Moore Investigation of antitumor effects of synthetic epothilone analogs in human myeloma models in vitro and in vivo Proc. Natl Acad. Sci. USA 102 2005 10640 10645 (Pubitemid 41061607)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.30
, pp. 10640-10645
-
-
Wu, K.-D.1
Cho, Y.S.2
Katz, J.3
Ponomarev, V.4
Chen-Kiang, S.5
Danishefsky, S.J.6
Moore, M.A.S.7
-
26
-
-
33746599829
-
Interaction of 4-arylcoumarin analogues of combretastatins with microtubule network of HBL100 cells and binding to tubulin
-
DOI 10.1021/bi060476g
-
C. Rappl, P. Barbier, V. Bourgarel-Rey, C. Gregoire, R. Gilli, M. Carre, S. Combes, J.P. Finet, and V. Peyrot Interaction of 4-arylcoumarin analogues of combretastatins with microtubule network of HBL100 cells and binding to tubulin Biochemistry 45 2006 9210 9218 (Pubitemid 44156384)
-
(2006)
Biochemistry
, vol.45
, Issue.30
, pp. 9210-9218
-
-
Rappl, C.1
Barbier, P.2
Bourgarel-Rey, V.3
Gregoire, C.4
Gilli, R.5
Carre, M.6
Combes, S.7
Finet, J.-P.8
Peyrot, V.9
-
28
-
-
19944428071
-
Patupilone (epothilone B) inhibits growth and survival of multiple myeloma cells in vitro and in vivo
-
DOI 10.1182/blood-2004-06-2499
-
B. Lin, L. Catley, R. LeBlanc, C. Mitsiades, R. Burger, Y.T. Tai, K. Podar, M. Wartmann, D. Chauhan, J.D. Griffin, and K.C. Anderson Patupilone (epothilone B) inhibits growth and survival of multiple myeloma cells in vitro and in vivo Blood 105 2005 350 357 (Pubitemid 40053103)
-
(2005)
Blood
, vol.105
, Issue.1
, pp. 350-357
-
-
Lin, B.1
Catley, L.2
LeBlanc, R.3
Mitsiades, C.4
Burger, R.5
Tai, Y.-T.6
Podar, K.7
Wartmann, M.8
Chauhan, D.9
Griffin, J.D.10
Anderson, K.C.11
-
29
-
-
0027196777
-
Taxol induces internucleosomal DNA fragmentation associated with programmed cell death in human myeloid leukemia cells
-
K. Bhalla, A.M. Ibrado, E. Tourkina, C. Tang, M.E. Mahoney, and Y. Huang Taxol induces internucleosomal DNA fragmentation associated with programmed cell death in human myeloid leukemia cells Leukemia 7 1993 563 568 (Pubitemid 23139860)
-
(1993)
Leukemia
, vol.7
, Issue.4
, pp. 563-568
-
-
Bhalla, K.1
Ibrado, A.M.2
Tourkina, E.3
Tang, C.4
Mahoney, M.E.5
Huang, Y.6
-
30
-
-
7444269580
-
Antiangiogenic activity of paclitaxel is associated with its cytostatic effect, mediated by the initiation but not completion of a mitochondrial apoptotic signaling pathway
-
E. Pasquier, M. Carre, B. Pourroy, L. Camoin, O. Rebai, C. Briand, and D. Braguer Antiangiogenic activity of paclitaxel is associated with its cytostatic effect, mediated by the initiation but not completion of a mitochondrial apoptotic signaling pathway Mol. Cancer Ther. 3 2004 1301 1310 (Pubitemid 39440174)
-
(2004)
Molecular Cancer Therapeutics
, vol.3
, Issue.10
, pp. 1301-1310
-
-
Pasquier, E.1
Carre, M.2
Pourroy, B.3
Camoin, L.4
Rebai, O.5
Briand, C.6
Braguer, D.7
-
31
-
-
0035150786
-
Anti-vascular effects of vinflunine in the MAC 15A transplantable adenocarcinoma model
-
DOI 10.1054/bjoc.2000.1587
-
S.E. Holwell, B.T. Hill, and M.C. Bibby Anti-vascular effects of vinflunine in the MAC 15A transplantable adenocarcinoma model Br. J. Cancer 84 2001 290 295 (Pubitemid 32113459)
-
(2001)
British Journal of Cancer
, vol.84
, Issue.2
, pp. 290-295
-
-
Holwell, S.E.1
Hill, B.T.2
Bibby, M.C.3
-
32
-
-
0034575597
-
Caspase-8 activation independent of CD95/CD95-L interaction during paclitaxel-induced apoptosis in human colon cancer cells (HT29-D4)
-
A. Goncalves, D. Braguer, G. Carles, N. Andre, C. Prevot, and C. Briand Caspase-8 activation independent of CD95/CD95-L interaction during paclitaxel-induced apoptosis in human colon cancer cells (HT29-D4) Biochem. Pharmacol. 60 2000 1579 1584
-
(2000)
Biochem. Pharmacol.
, vol.60
, pp. 1579-1584
-
-
Goncalves, A.1
Braguer, D.2
Carles, G.3
Andre, N.4
Prevot, C.5
Briand, C.6
-
33
-
-
2642563086
-
Death receptor-dependent and -independent pathways in anticancer drug-induced apoptosis of breast cancer cells
-
R. Kim, K. Tanabe, M. Emi, Y. Uchida, and T. Toge Death receptor-dependent and -independent pathways in anticancer drug-induced apoptosis of breast cancer cells Oncol. Rep. 10 2003 1925 1930
-
(2003)
Oncol. Rep.
, vol.10
, pp. 1925-1930
-
-
Kim, R.1
Tanabe, K.2
Emi, M.3
Uchida, Y.4
Toge, T.5
-
34
-
-
33746886979
-
Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
-
DOI 10.1038/sj.onc.1209608, PII 1209608
-
S. Fulda, and K.M. Debatin Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy Oncogene 25 2006 4798 4811 (Pubitemid 44187627)
-
(2006)
Oncogene
, vol.25
, Issue.34
, pp. 4798-4811
-
-
Fulda, S.1
Debatin, K.-M.2
-
35
-
-
0037021417
-
Paclitaxel targets mitochondria upstream of caspase activation in intact human neuroblastoma cells
-
DOI 10.1016/S0014-5793(02)03691-8, PII S0014579302036918
-
N. Andre, M. Carre, G. Brasseur, B. Pourroy, H. Kovacic, C. Briand, and D. Braguer Paclitaxel targets mitochondria upstream of caspase activation in intact human neuroblastoma cells FEBS Lett. 532 2002 256 260 (Pubitemid 35375900)
-
(2002)
FEBS Letters
, vol.532
, Issue.1-2
, pp. 256-260
-
-
Andre, N.1
Carre, M.2
Brasseur, G.3
Pourroy, B.4
Kovacic, H.5
Briand, C.6
Braguer, D.7
-
36
-
-
51049100659
-
Activation of the mitochondria-driven pathway of apoptosis in human PC-3 prostate cancer cells by a novel hydrophilic paclitaxel derivative, 7-xylosyl-10-deacetylpaclitaxel
-
S. Jiang, Y. Zu, Y. Fu, Y. Zhang, and T. Efferth Activation of the mitochondria-driven pathway of apoptosis in human PC-3 prostate cancer cells by a novel hydrophilic paclitaxel derivative, 7-xylosyl-10-deacetylpaclitaxel Int. J. Oncol. 33 2008 103 111
-
(2008)
Int. J. Oncol.
, vol.33
, pp. 103-111
-
-
Jiang, S.1
Zu, Y.2
Fu, Y.3
Zhang, Y.4
Efferth, T.5
-
37
-
-
47949124685
-
2
-
2 Langmuir 24 2008 7432 7441
-
(2008)
Langmuir
, vol.24
, pp. 7432-7441
-
-
Kang, Y.1
Wu, J.2
Yin, G.3
Huang, Z.4
Liao, X.5
Yao, Y.6
Ouyang, P.7
Wang, H.8
Yang, Q.9
-
38
-
-
0034016574
-
Mass spectrometric identification of proteins released from mitochondria undergoing permeability transition
-
S.D. Patterson, C.S. Spahr, E. Daugas, S.A. Susin, T. Irinopoulou, C. Koehler, and G. Kroemer Mass spectrometric identification of proteins released from mitochondria undergoing permeability transition Cell Death Differ. 7 2000 137 144 (Pubitemid 30150781)
-
(2000)
Cell Death and Differentiation
, vol.7
, Issue.2
, pp. 137-144
-
-
Patterson, S.D.1
Spahr, C.S.2
Daugas, E.3
Susin, S.A.4
Irinopoulou, T.5
Koehler, C.6
Kroemer, G.7
-
39
-
-
0036119432
-
A matrix-assisted laser desorption ionization post-source decay (MALDI-PSD) analysis of proteins released from isolated liver mitochondria treated with recombinant truncated Bid
-
DOI 10.1038/sj.cdd.4400966
-
G. Van Loo, H. Demol, M. van Gurp, B. Hoorelbeke, P. Schotte, R. Beyaert, B. Zhivotovsky, K. Gevaert, W. Declercq, J. Vandekerckhove, and P. Vandenabeele A matrix-assisted laser desorption ionization post-source decay (MALDI-PSD) analysis of proteins released from isolated liver mitochondria treated with recombinant truncated Bid Cell Death Differ. 9 2002 301 308 (Pubitemid 34223873)
-
(2002)
Cell Death and Differentiation
, vol.9
, Issue.3
, pp. 301-308
-
-
Van Loo, G.1
Demol, H.2
Van Gurp, M.3
Hoorelbeke, B.4
Schotte, P.5
Beyaert, R.6
Zhivotovsky, B.7
Gevaert, K.8
Declercq, W.9
Vandekerckhove, J.10
Vandenabeele, P.11
-
40
-
-
0037033711
-
Characterization of cell death induced by vinflunine, the most recent vinca alkaloid in clinical development
-
DOI 10.1038/sj.bjc.6600025
-
A. Kruczynski, C. Etievant, D. Perrin, N. Chansard, A. Duflos, and B.T. Hill Characterization of cell death induced by vinflunine, the most recent Vinca alkaloid in clinical development Br. J. Cancer 86 2002 143 150 (Pubitemid 34146355)
-
(2002)
British Journal of Cancer
, vol.86
, Issue.1
, pp. 143-150
-
-
Kruczynski, A.1
Etievant, C.2
Perrin, D.3
Chansard, N.4
Duflos, A.5
Hill, B.T.6
-
41
-
-
10944257440
-
Taxol induces caspase-10-dependent apoptosis
-
DOI 10.1074/jbc.M406543200
-
S.J. Park, C.H. Wu, J.D. Gordon, X. Zhong, A. Emami, and A.R. Safa Taxol induces caspase-10-dependent apoptosis J. Biol. Chem. 279 2004 51057 51067 (Pubitemid 40017847)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.49
, pp. 51057-51067
-
-
Park, S.-J.1
Wu, C.-H.2
Gordon, J.D.3
Zhong, X.4
Emami, A.5
Safa, A.R.6
-
42
-
-
0034654517
-
The role of Apaf-1, caspase-9, and Bid proteins in etoposide- or paclitaxel-induced mitochondrial events during apoptosis
-
C.L. Perkins, G. Fang, C.N. Kim, and K.N. Bhalla The role of Apaf-1, caspase-9, and bid proteins in etoposide- or paclitaxel-induced mitochondrial events during apoptosis Cancer Res. 60 2000 1645 1653 (Pubitemid 30183437)
-
(2000)
Cancer Research
, vol.60
, Issue.6
, pp. 1645-1653
-
-
Perkins, C.L.1
Fang, G.2
Kim, C.N.3
Bhalla, K.N.4
-
43
-
-
12244251385
-
Involvement of mitochondrial pathway in Taxol-induced apoptosis of human T24 bladder cancer cells
-
S.Y. Yuan, S.L. Hsu, K.J. Tsai, and C.R. Yang Involvement of mitochondrial pathway in Taxol-induced apoptosis of human T24 bladder cancer cells Urol. Res. 30 2002 282 288
-
(2002)
Urol. Res.
, vol.30
, pp. 282-288
-
-
Yuan, S.Y.1
Hsu, S.L.2
Tsai, K.J.3
Yang, C.R.4
-
44
-
-
0141757448
-
Apoptotic pathways of epothilone BMS 310705
-
DOI 10.1016/S0090-8258(03)00481-5
-
D. Uyar, N. Takigawa, T. Mekhail, D. Grabowski, M. Markman, F. Lee, R. Canetta, R. Peck, R. Bukowski, and R. Ganapathi Apoptotic pathways of epothilone BMS 310705 Gynecol. Oncol. 91 2003 173 178 (Pubitemid 37188608)
-
(2003)
Gynecologic Oncology
, vol.91
, Issue.1
, pp. 173-178
-
-
Uyar, D.1
Takigawa, N.2
Mekhail, T.3
Grabowski, D.4
Markman, M.5
Lee, F.6
Canetta, R.7
Peck, R.8
Bukowski, R.9
Ganapathi, R.10
-
45
-
-
0032532653
-
Overexpression of Apaf-1 promotes apoptosis of untreated and paclitaxel- or etoposide-treated HL-60 cells
-
C. Perkins, C.N. Kim, G. Fang, and K.N. Bhalla Overexpression of Apaf-1 promotes apoptosis of untreated and paclitaxel- or etoposide-treated HL-60 cells Cancer Res. 58 1998 4561 4566 (Pubitemid 28480614)
-
(1998)
Cancer Research
, vol.58
, Issue.20
, pp. 4561-4566
-
-
Perkins, C.1
Kim, C.N.2
Fang, G.3
Bhalla, K.N.4
-
46
-
-
0035901938
-
Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance
-
DOI 10.1038/sj.onc.1204342
-
K. Friedrich, T. Wieder, C. Von Haefen, S. Radetzki, R. Janicke, K. Schulze-Osthoff, B. Dorken, and P.T. Daniel Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance Oncogene 20 2001 2749 2760 (Pubitemid 32549832)
-
(2001)
Oncogene
, vol.20
, Issue.22
, pp. 2749-2760
-
-
Friedrich, K.1
Wieder, T.2
Von Haefen, C.3
Radetzki, S.4
Janicke, R.5
Schulze-Osthoff, K.6
Dorken, B.7
Daniel, P.T.8
-
47
-
-
0034710649
-
Structural and biochemical basis of apoptotic activation by Smac/DIABLO
-
DOI 10.1038/35022514
-
J. Chai, C. Du, J.W. Wu, S. Kyin, X. Wang, and Y. Shi Structural and biochemical basis of apoptotic activation by Smac/DIABLO Nature 406 2000 855 862 (Pubitemid 30664254)
-
(2000)
Nature
, vol.406
, Issue.6798
, pp. 855-862
-
-
Chai, J.1
Du, C.2
Wu, J.-W.3
Kyin, S.4
Wang, X.5
Shi, Y.6
-
48
-
-
48249140223
-
Smac/DIABLO enhances the therapeutic potential of chemotherapeutic drugs and irradiation, and sensitizes TRAIL-resistant breast cancer cells
-
T.E. Fandy, S. Shankar, and R.K. Srivastava Smac/DIABLO enhances the therapeutic potential of chemotherapeutic drugs and irradiation, and sensitizes TRAIL-resistant breast cancer cells Mol. Cancer 7 2008 60
-
(2008)
Mol. Cancer
, vol.7
, pp. 60
-
-
Fandy, T.E.1
Shankar, S.2
Srivastava, R.K.3
-
49
-
-
0347895102
-
Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ
-
DOI 10.1074/jbc.M207578200
-
C.R. Arnt, M.V. Chiorean, M.P. Heldebrant, G.J. Gores, and S.H. Kaufmann Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ J. Biol. Chem. 277 2002 44236 44243 (Pubitemid 36157856)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.46
, pp. 44236-44243
-
-
Arnt, C.R.1
Chiorean, M.V.2
Heldebrant, M.P.3
Gores, G.J.4
Kaufmann, S.H.5
-
50
-
-
0038297558
-
Expression of Smac/DIABLO in ovarian carcinoma cells induces apoptosis via a caspase-9-mediated pathway
-
DOI 10.1016/S0014-4827(03)00073-9
-
I.A. McNeish, S. Bell, T. McKay, T. Tenev, M. Marani, and N.R. Lemoine Expression of Smac/DIABLO in ovarian carcinoma cells induces apoptosis via a caspase-9-mediated pathway Exp. Cell Res. 286 2003 186 198 (Pubitemid 36566432)
-
(2003)
Experimental Cell Research
, vol.286
, Issue.2
, pp. 186-198
-
-
McNeish, I.A.1
Bell, S.2
McKay, T.3
Tenev, T.4
Marani, M.5
Lemoine, N.R.6
-
51
-
-
36249022057
-
Transfection of Smac/DIABLO sensitizes drug-resistant tumor cells to TRAIL or paclitaxel-induced apoptosis in vitro
-
DOI 10.1016/j.phrs.2007.09.010, PII S1043661807001697
-
H.L. Mao, P.S. Liu, J.F. Zheng, P.H. Zhang, L.G. Zhou, G. Xin, and C. Liu Transfection of Smac/DIABLO sensitizes drug-resistant tumor cells to TRAIL or paclitaxel-induced apoptosis in vitro Pharmacol. Res. 56 2007 483 492 (Pubitemid 350137770)
-
(2007)
Pharmacological Research
, vol.56
, Issue.6
, pp. 483-492
-
-
Mao, H.L.1
Liu, P.S.2
Zheng, J.F.3
Zhang, P.H.4
Zhou, L.G.5
Xin, G.6
Liu, C.7
-
52
-
-
33745953139
-
BCL-2 in the crosshairs: Tipping the balance of life and death
-
DOI 10.1038/sj.cdd.4401992, PII 4401992
-
L.D. Walensky BCL-2 in the crosshairs: tipping the balance of life and death Cell Death Differ. 13 2006 1339 1350 (Pubitemid 44057469)
-
(2006)
Cell Death and Differentiation
, vol.13
, Issue.8
, pp. 1339-1350
-
-
Walensky, L.D.1
-
53
-
-
0031747118
-
Cisplatin- and paclitaxel-induced apoptosis of ovarian carcinoma cells and the relationship between Bax and Bak up-regulation and the functional status of p53
-
N.A. Jones, J. Turner, A.J. McIlwrath, R. Brown, and C. Dive Cisplatin- and paclitaxel-induced apoptosis of ovarian carcinoma cells and the relationship between bax and bak up-regulation and the functional status of p53 Mol. Pharmacol. 53 1998 819 826 (Pubitemid 28244068)
-
(1998)
Molecular Pharmacology
, vol.53
, Issue.5
, pp. 819-826
-
-
Jones, N.A.1
Turner, J.2
McIlwrath, A.J.3
Brown, R.4
Dive, C.5
-
54
-
-
4544381708
-
Regulation of Bax activation and apoptotic response to microtubule-damaging agents by p53 transcription-dependent and -independent pathways
-
DOI 10.1074/jbc.M401530200
-
H. Yamaguchi, J. Chen, K. Bhalla, and H.G. Wang Regulation of Bax activation and apoptotic response to microtubule-damaging agents by p53 transcription-dependent and -independent pathways J. Biol. Chem. 279 2004 39431 39437 (Pubitemid 39258208)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.38
, pp. 39431-39437
-
-
Yamaguchi, H.1
Chen, J.2
Bhalla, K.3
Wang, H.-G.4
-
55
-
-
0034064991
-
Susceptibility to drug-induced apoptosis correlates with differential modulation of Bad, Bcl-2 and Bcl-x(L) protein levels
-
G. Tudor, A. Aguilera, D.O. Halverson, N.D. Laing, and E.A. Sausville Susceptibility to drug-induced apoptosis correlates with differential modulation of Bad, Bcl-2 and Bcl-xL protein levels Cell Death Differ. 7 2000 574 586 (Pubitemid 30303613)
-
(2000)
Cell Death and Differentiation
, vol.7
, Issue.6
, pp. 574-586
-
-
Tudor, G.1
Aguilera, A.2
Halverson, D.O.3
Laing, N.D.4
Sausville, E.A.5
-
56
-
-
0032511891
-
BAD partly reverses paclitaxel resistance in human ovarian cancer cells
-
T. Strobel, Y.T. Tai, S. Korsmeyer, and S.A. Cannistra BAD partly reverses paclitaxel resistance in human ovarian cancer cells Oncogene 17 1998 2419 2427 (Pubitemid 28544711)
-
(1998)
Oncogene
, vol.17
, Issue.19
, pp. 2419-2427
-
-
Strobel, T.1
Tai, Y.-T.2
Korsmeyer, S.3
Cannistra, S.A.4
-
57
-
-
0034164496
-
Bax overexpression enhances cytochrome c release from mitochondria and sensitizes KATOIII gastric cancer cells to chemotherapeutic agent-induced apoptosis
-
H. Sawa, T. Kobayashi, K. Mukai, W. Zhang, and H. Shiku Bax overexpression enhances cytochrome c release from mitochondria and sensitizes KATOIII gastric cancer cells to chemotherapeutic agent-induced apoptosis Int. J. Oncol. 16 2000 745 749
-
(2000)
Int. J. Oncol.
, vol.16
, pp. 745-749
-
-
Sawa, H.1
Kobayashi, T.2
Mukai, K.3
Zhang, W.4
Shiku, H.5
-
58
-
-
0028979438
-
Overexpression of Bcl-XS sensitizes MCF-7 cells to chemotherapy-induced apoptosis
-
V.N. Sumantran, M.W. Ealovega, G. Nunez, M.F. Clarke, and M.S. Wicha Overexpression of Bcl-XS sensitizes MCF-7 cells to chemotherapy-induced apoptosis Cancer Res. 55 1995 2507 2510
-
(1995)
Cancer Res.
, vol.55
, pp. 2507-2510
-
-
Sumantran, V.N.1
Ealovega, M.W.2
Nunez, G.3
Clarke, M.F.4
Wicha, M.S.5
-
59
-
-
0035890335
-
Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate
-
DOI 10.1093/emboj/20.22.6306
-
G.W. Makin, B.M. Corfe, G.J. Griffiths, A. Thistlethwaite, J.A. Hickman, and C. Dive Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate EMBO J. 20 2001 6306 6315 (Pubitemid 33078704)
-
(2001)
EMBO Journal
, vol.20
, Issue.22
, pp. 6306-6315
-
-
Makin, G.W.J.1
Corfe, B.M.2
Griffiths, G.J.3
Thistlethwaite, A.4
Hickman, J.A.5
Dive, C.6
-
60
-
-
0035853811
-
Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells
-
B. Antonsson, S. Montessuit, B. Sanchez, and J.C. Martinou Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells J. Biol. Chem. 276 2001 11615 11623
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 11615-11623
-
-
Antonsson, B.1
Montessuit, S.2
Sanchez, B.3
Martinou, J.C.4
-
61
-
-
0038515279
-
The N-terminal end of Bax contains a mitochondrial-targeting signal
-
DOI 10.1074/jbc.M208955200
-
P.F. Cartron, M. Priault, L. Oliver, K. Meflah, S. Manon, and F.M. Vallette The N-terminal end of Bax contains a mitochondrial-targeting signal J. Biol. Chem. 278 2003 11633 11641 (Pubitemid 36792725)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.13
, pp. 11633-11641
-
-
Cartron, P.-F.1
Priault, M.2
Oliver, L.3
Meflah, K.4
Manon, S.5
Vallette, F.M.6
-
62
-
-
0037385915
-
Molecular determinants of epothilone B derivative (BMS 247550) and Apo-2L/TRAIL-induced apoptosis of human ovarian cancer cells
-
DOI 10.1016/S0090-8258(03)00006-4
-
D. Griffin, S. Wittmann, F. Guo, R. Nimmanapalli, P. Bali, H.G. Wang, and K. Bhalla Molecular determinants of epothilone B derivative (BMS 247550) and Apo-2L/TRAIL-induced apoptosis of human ovarian cancer cells Gynecol. Oncol. 89 2003 37 47 (Pubitemid 36403645)
-
(2003)
Gynecologic Oncology
, vol.89
, Issue.1
, pp. 37-47
-
-
Griffin, D.1
Wittmann, S.2
Guo, F.3
Nimmanapalli, R.4
Bali, P.5
Wang, H.G.6
Bhalla, K.7
-
63
-
-
0036184739
-
Paclitaxel triggers cell death primarily via caspase-independent routes in the non-small cell lung cancer cell line NCI-H460
-
C. Huisman, C.G. Ferreira, L.E. Broker, J.A. Rodriguez, E.F. Smit, P.E. Postmus, F.A. Kruyt, and G. Giaccone Paclitaxel triggers cell death primarily via caspase-independent routes in the non-small cell lung cancer cell line NCI-H460 Clin. Cancer Res. 8 2002 596 606 (Pubitemid 34193982)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.2
, pp. 596-606
-
-
Huisman, C.1
Ferreira, C.G.2
Broker, L.E.3
Rodriguez, J.A.4
Smit, E.F.5
Postmus, P.E.6
Kruyt, F.A.E.7
Giaccone, G.8
-
64
-
-
12444306413
-
Characterization of vinblastine-induced Bcl-xL and Bcl-2 phosphorylation: Evidence for a novel protein kinase and a coordinated phosphorylation/ dephosphorylation cycle associated with apoptosis induction
-
DOI 10.1038/sj.onc.1208189
-
L. Du, C.S. Lyle, and T.C. Chambers Characterization of vinblastine-induced Bcl-xL and Bcl-2 phosphorylation: evidence for a novel protein kinase and a coordinated phosphorylation/dephosphorylation cycle associated with apoptosis induction Oncogene 24 2005 107 117 (Pubitemid 40143870)
-
(2005)
Oncogene
, vol.24
, Issue.1
, pp. 107-117
-
-
Du, L.1
Lyle, C.S.2
Chambers, T.C.3
-
65
-
-
0035093701
-
Microtubule-targeting drugs induce Bcl-2 phosphorylation and association with Pin1
-
N. Pathan, C. Aime-Sempe, S. Kitada, S. Haldar, and J.C. Reed Microtubule-targeting drugs induce Bcl-2 phosphorylation and association with Pin1 Neoplasia 3 2001 70 79 (Pubitemid 32201612)
-
(2001)
Neoplasia
, vol.3
, Issue.1
, pp. 70-79
-
-
Pathan, N.1
Aime-Sempe, C.2
Kitada, S.3
Haldar, S.4
Reed, J.C.5
-
66
-
-
0029964257
-
Taxol induces bcl-2 phosphorylation and death of prostate cancer cells
-
S. Haldar, J. Chintapalli, and C.M. Croce Taxol induces bcl-2 phosphorylation and death of prostate cancer cells Cancer Res. 56 1996 1253 1255 (Pubitemid 26080965)
-
(1996)
Cancer Research
, vol.56
, Issue.6
, pp. 1253-1255
-
-
Haldar, S.1
Chintapalli, J.2
Croce, C.M.3
-
67
-
-
0036295952
-
PP1 phosphatase is involved in Bcl-2 dephosphorylation after prolonged mitotic arrest induced by paclitaxel
-
DOI 10.1016/S0006-291X(02)00505-3, PII S0006291X02005053
-
L. Brichese, and A. Valette PP1 phosphatase is involved in Bcl-2 dephosphorylation after prolonged mitotic arrest induced by paclitaxel Biochem. Biophys. Res. Commun. 294 2002 504 508 (Pubitemid 34694122)
-
(2002)
Biochemical and Biophysical Research Communications
, vol.294
, Issue.2
, pp. 504-508
-
-
Brichese, L.1
Valette, A.2
-
68
-
-
0032514914
-
Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and taxol-induced growth arrest
-
DOI 10.1074/jbc.273.46.30777
-
C.D. Scatena, Z.A. Stewart, D. Mays, L.J. Tang, C.J. Keefer, S.D. Leach, and J.A. Pietenpol Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol-induced growth arrest J. Biol. Chem. 273 1998 30777 30784 (Pubitemid 28545562)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.46
, pp. 30777-30784
-
-
Scatena, C.D.1
Stewart, Z.A.2
Mays, D.3
Tang, L.J.4
Keefer, C.J.5
Leach, S.D.6
Pietenpol, J.A.7
-
69
-
-
0033708421
-
Modulation of mitogen-activated protein kinases and phosphorylation of Bcl-2 by vinblastine represent persistent forms of normal fluctuations at G2-M1
-
M. Fan, L. Du, A.A. Stone, K.M. Gilbert, and T.C. Chambers Modulation of mitogen-activated protein kinases and phosphorylation of Bcl-2 by vinblastine represent persistent forms of normal fluctuations at G2-M1 Cancer Res. 60 2000 6403 6407
-
(2000)
Cancer Res.
, vol.60
, pp. 6403-6407
-
-
Fan, M.1
Du, L.2
Stone, A.A.3
Gilbert, K.M.4
Chambers, T.C.5
-
70
-
-
0037608711
-
Chemotherapy-induced apoptosis and Bcl-2 levels correlate with breast cancer response to chemotherapy
-
T.A. Buchholz, D.W. Davis, D.J. McConkey, W.F. Symmans, V. Valero, A. Jhingran, S.L. Tucker, L. Pusztai, M. Cristofanilli, F.J. Esteva, G.N. Hortobagyi, and A.A. Sahin Chemotherapy-induced apoptosis and Bcl-2 levels correlate with breast cancer response to chemotherapy Cancer J. 9 2003 33 41
-
(2003)
Cancer J.
, vol.9
, pp. 33-41
-
-
Buchholz, T.A.1
Davis, D.W.2
McConkey, D.J.3
Symmans, W.F.4
Valero, V.5
Jhingran, A.6
Tucker, S.L.7
Pusztai, L.8
Cristofanilli, M.9
Esteva, F.J.10
Hortobagyi, G.N.11
Sahin, A.A.12
-
71
-
-
33646236796
-
Decrease in c-Myc activity enhances cancer cell sensitivity to vinblastine
-
C. Bressin, V. Bourgarel-Rey, M. Carre, B. Pourroy, D. Arango, D. Braguer, and Y. Barra Decrease in c-Myc activity enhances cancer cell sensitivity to vinblastine Anticancer Drugs 17 2006 181 187
-
(2006)
Anticancer Drugs
, vol.17
, pp. 181-187
-
-
Bressin, C.1
Bourgarel-Rey, V.2
Carre, M.3
Pourroy, B.4
Arango, D.5
Braguer, D.6
Barra, Y.7
-
72
-
-
33645967518
-
Evidence that low doses of Taxol enhance the functional transactivatory properties of p53 on p21 waf promoter in MCF-7 breast cancer cells
-
M.L. Panno, F. Giordano, F. Mastroianni, C. Morelli, E. Brunelli, M.G. Palma, M. Pellegrino, S. Aquila, A. Miglietta, L. Mauro, D. Bonofiglio, and S. Ando Evidence that low doses of Taxol enhance the functional transactivatory properties of p53 on p21 waf promoter in MCF-7 breast cancer cells FEBS Lett. 580 2006 2371 2380
-
(2006)
FEBS Lett.
, vol.580
, pp. 2371-2380
-
-
Panno, M.L.1
Giordano, F.2
Mastroianni, F.3
Morelli, C.4
Brunelli, E.5
Palma, M.G.6
Pellegrino, M.7
Aquila, S.8
Miglietta, A.9
Mauro, L.10
Bonofiglio, D.11
Ando, S.12
-
73
-
-
33750723137
-
Bcl-2 expression as a predictive marker of hormone-refractory prostate cancer treated with taxane-based chemotherapy
-
DOI 10.1158/1078-0432.CCR-06-0147
-
T. Yoshino, H. Shiina, S. Urakami, N. Kikuno, T. Yoneda, K. Shigeno, and M. Igawa Bcl-2 expression as a predictive marker of hormone-refractory prostate cancer treated with taxane-based chemotherapy Clin. Cancer Res. 12 2006 6116 6124 (Pubitemid 44703777)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.20 PART 1
, pp. 6116-6124
-
-
Yoshino, T.1
Shiina, H.2
Urakami, S.3
Kikuno, N.4
Yoneda, T.5
Shigeno, K.6
Igawa, M.7
-
74
-
-
0034326272
-
Bcl-xL in prostate cancer cells: Effects of overexpression and down-regulation on chemosensitivity
-
I. Lebedeva, R. Rando, J. Ojwang, P. Cossum, and C.A. Stein Bcl-xL in prostate cancer cells: effects of overexpression and down-regulation on chemosensitivity Cancer Res. 60 2000 6052 6060
-
(2000)
Cancer Res.
, vol.60
, pp. 6052-6060
-
-
Lebedeva, I.1
Rando, R.2
Ojwang, J.3
Cossum, P.4
Stein, C.A.5
-
75
-
-
36849084779
-
CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice
-
DOI 10.1172/JCI32481
-
X. Tang, Y. Zhu, L. Han, A.L. Kim, L. Kopelovich, D.R. Bickers, and M. Athar CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice J. Clin. Invest. 117 2007 3753 3764 (Pubitemid 350224086)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.12
, pp. 3753-3764
-
-
Tang, X.1
Zhu, Y.2
Han, L.3
Kim, A.L.4
Kopelovich, L.5
Bickers, D.R.6
Athar, M.7
-
76
-
-
48549095021
-
Improved cellular pharmacokinetics and pharmacodynamics underlie the wide anticancer activity of sagopilone
-
J. Hoffmann, I. Vitale, B. Buchmann, L. Galluzzi, W. Schwede, L. Senovilla, W. Skuballa, S. Vivet, R.B. Lichtner, J.M. Vicencio, T. Panaretakis, G. Siemeister, H. Lage, L. Nanty, S. Hammer, K. Mittelstaedt, S. Winsel, J. Eschenbrenner, M. Castedo, C. Demarche, U. Klar, and G. Kroemer Improved cellular pharmacokinetics and pharmacodynamics underlie the wide anticancer activity of sagopilone Cancer Res. 68 2008 5301 5308
-
(2008)
Cancer Res.
, vol.68
, pp. 5301-5308
-
-
Hoffmann, J.1
Vitale, I.2
Buchmann, B.3
Galluzzi, L.4
Schwede, W.5
Senovilla, L.6
Skuballa, W.7
Vivet, S.8
Lichtner, R.B.9
Vicencio, J.M.10
Panaretakis, T.11
Siemeister, G.12
Lage, H.13
Nanty, L.14
Hammer, S.15
Mittelstaedt, K.16
Winsel, S.17
Eschenbrenner, J.18
Castedo, M.19
Demarche, C.20
Klar, U.21
Kroemer, G.22
more..
-
77
-
-
34548736559
-
Therapeutic integration of c-myc and bcl-2 antisense molecules with docetaxel in a preclinical model of hormone-refractory prostate cancer
-
DOI 10.1002/pros.20636
-
C. Leonetti, A. Biroccio, C. D'Angelo, S.C. Semple, M. Scarsella, and G. Zupi Therapeutic integration of c-myc and bcl-2 antisense molecules with docetaxel in a preclinical model of hormone-refractory prostate cancer Prostate 67 2007 1475 1485 (Pubitemid 47435794)
-
(2007)
Prostate
, vol.67
, Issue.13
, pp. 1475-1485
-
-
Leonetti, C.1
Biroccio, A.2
D'Angelo, C.3
Semple, S.C.4
Scarsella, M.5
Zupi, G.6
-
78
-
-
0242539538
-
Antisense Bcl-2 and HER-2 oligonucleotide treatment of breast cancer cells enhances their sensitivity to anticancer drugs
-
K. Tanabe, R. Kim, H. Inoue, M. Emi, Y. Uchida, and T. Toge Antisense Bcl-2 and HER-2 oligonucleotide treatment of breast cancer cells enhances their sensitivity to anticancer drugs Int. J. Oncol. 22 2003 875 881
-
(2003)
Int. J. Oncol.
, vol.22
, pp. 875-881
-
-
Tanabe, K.1
Kim, R.2
Inoue, H.3
Emi, M.4
Uchida, Y.5
Toge, T.6
-
79
-
-
33745191622
-
Induction of apoptosis and enhancement of chemosensitivity in human prostate cancer LNCaP cells using bispecific antisense oligonucleotide targeting Bcl-2 and Bcl-xL genes
-
DOI 10.1111/j.1464-410X.2006.06147.x
-
K. Yamanaka, P. Rocchi, H. Miyake, L. Fazli, A. So, U. Zangemeister-Wittke, and M.E. Gleave Induction of apoptosis and enhancement of chemosensitivity in human prostate cancer LNCaP cells using bispecific antisense oligonucleotide targeting Bcl-2 and Bcl-xL genes BJU Int. 97 2006 1300 1308 (Pubitemid 43907340)
-
(2006)
BJU International
, vol.97
, Issue.6
, pp. 1300-1308
-
-
Yamanaka, K.1
Rocchi, P.2
Miyake, H.3
Fazli, L.4
So, A.5
Zangemeister-Wittke, U.6
Gleave, M.E.7
-
80
-
-
54249093808
-
Alteration of the mitochondrial apoptotic pathway is key to acquired paclitaxel resistance and can be reversed by ABT-737
-
O. Kutuk, and A. Letai Alteration of the mitochondrial apoptotic pathway is key to acquired paclitaxel resistance and can be reversed by ABT-737 Cancer Res. 68 2008 7985 7994
-
(2008)
Cancer Res.
, vol.68
, pp. 7985-7994
-
-
Kutuk, O.1
Letai, A.2
-
81
-
-
20444486559
-
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
-
DOI 10.1038/nature03579
-
T. Oltersdorf, S.W. Elmore, A.R. Shoemaker, R.C. Armstrong, D.J. Augeri, B.A. Belli, M. Bruncko, T.L. Deckwerth, J. Dinges, P.J. Hajduk, M.K. Joseph, S. Kitada, S.J. Korsmeyer, A.R. Kunzer, A. Letai, C. Li, M.J. Mitten, D.G. Nettesheim, S. Ng, P.M. Nimmer, J.M. O'Connor, A. Oleksijew, A.M. Petros, J.C. Reed, W. Shen, S.K. Tahir, C.B. Thompson, K.J. Tomaselli, B. Wang, M.D. Wendt, H. Zhang, S.W. Fesik, and S.H. Rosenberg An inhibitor of Bcl-2 family proteins induces regression of solid tumours Nature 435 2005 677 681 (Pubitemid 40825512)
-
(2005)
Nature
, vol.435
, Issue.7042
, pp. 677-681
-
-
Oltersdorf, T.1
Elmore, S.W.2
Shoemaker, A.R.3
Armstrong, R.C.4
Augeri, D.J.5
Belli, B.A.6
Bruncko, M.7
Deckwerth, T.L.8
Dinges, J.9
Hajduk, P.J.10
Joseph, M.K.11
Kitada, S.12
Korsmeyer, S.J.13
Kunzer, A.R.14
Letai, A.15
Li, C.16
Mitten, M.J.17
Nettesheim, D.G.18
Ng, S.19
Nimmer, P.M.20
O'Connor, J.M.21
Oleksijew, A.22
Petros, A.M.23
Reed, J.C.24
Shen, W.25
Tahir, S.K.26
Thompson, C.B.27
Tomaselli, K.J.28
Wang, B.29
Wendt, M.D.30
Zhang, H.31
Fesik, S.W.32
Rosenberg, S.H.33
more..
-
82
-
-
77954609010
-
Chemotherapeutic drugs sensitize human renal cell carcinoma cells to ABT-737 by a mechanism involving the Noxa-dependent inactivation of Mcl-1 or A1
-
H. Zall, A. Weber, R. Besch, N. Zantl, and G. Hacker Chemotherapeutic drugs sensitize human renal cell carcinoma cells to ABT-737 by a mechanism involving the Noxa-dependent inactivation of Mcl-1 or A1 Mol. Cancer 9 2010 164
-
(2010)
Mol. Cancer
, vol.9
, pp. 164
-
-
Zall, H.1
Weber, A.2
Besch, R.3
Zantl, N.4
Hacker, G.5
-
83
-
-
33749016520
-
L potentiates the activity of cytotoxic drugs in vitro and in vivo
-
DOI 10.1158/0008-5472.CAN-06-0367
-
A.R. Shoemaker, A. Oleksijew, J. Bauch, B.A. Belli, T. Borre, M. Bruncko, T. Deckwirth, D.J. Frost, K. Jarvis, M.K. Joseph, K. Marsh, W. McClellan, H. Nellans, S. Ng, P. Nimmer, J.M. O'Connor, T. Oltersdorf, W. Qing, W. Shen, J. Stavropoulos, S.K. Tahir, B. Wang, R. Warner, H. Zhang, S.W. Fesik, S.H. Rosenberg, and S.W. Elmore A small-molecule inhibitor of Bcl-XL potentiates the activity of cytotoxic drugs in vitro and in vivo Cancer Res. 66 2006 8731 8739 (Pubitemid 44449190)
-
(2006)
Cancer Research
, vol.66
, Issue.17
, pp. 8731-8739
-
-
Shoemaker, A.R.1
Oleksijew, A.2
Bauch, J.3
Belli, B.A.4
Borre, T.5
Bruncko, M.6
Deckwirth, T.7
Frost, D.J.8
Jarvis, K.9
Joseph, M.K.10
Marsh, K.11
McClellan, W.12
Nellans, H.13
Ng, S.14
Nimmer, P.15
O'Connor, J.M.16
Oltersdorf, T.17
Qing, W.18
Shen, W.19
Stavropoulos, J.20
Tahir, S.K.21
Wang, B.22
Warner, R.23
Zhang, H.24
Fesik, S.W.25
Rosenberg, S.H.26
Elmore, S.W.27
more..
-
84
-
-
70349490638
-
Bcl-2 modulation to activate apoptosis in prostate cancer
-
K. Bray, H.Y. Chen, C.M. Karp, M. May, S. Ganesan, V. Karantza-Wadsworth, R.S. DiPaola, and E. White Bcl-2 modulation to activate apoptosis in prostate cancer Mol. Cancer Res. 7 2009 1487 1496
-
(2009)
Mol. Cancer Res.
, vol.7
, pp. 1487-1496
-
-
Bray, K.1
Chen, H.Y.2
Karp, C.M.3
May, M.4
Ganesan, S.5
Karantza-Wadsworth, V.6
Dipaola, R.S.7
White, E.8
-
85
-
-
68449085118
-
Phase III randomised study of dexamethasone with or without oblimersen sodium for patients with advanced multiple myeloma
-
A.A. Chanan-Khan, R. Niesvizky, R.J. Hohl, T.M. Zimmerman, N.P. Christiansen, G.J. Schiller, N. Callander, J. Lister, M. Oken, and S. Jagannath Phase III randomised study of dexamethasone with or without oblimersen sodium for patients with advanced multiple myeloma Leuk. Lymphoma 50 2009 559 565
-
(2009)
Leuk. Lymphoma
, vol.50
, pp. 559-565
-
-
Chanan-Khan, A.A.1
Niesvizky, R.2
Hohl, R.J.3
Zimmerman, T.M.4
Christiansen, N.P.5
Schiller, G.J.6
Callander, N.7
Lister, J.8
Oken, M.9
Jagannath, S.10
-
86
-
-
34047217206
-
Randomized phase III trial of fludarabine plus cyclophosphamide with or without oblimersen sodium (Bcl-2 antisense) in patients with relapsed or refractory chronic lymphocytic leukemia
-
DOI 10.1200/JCO.2006.07.1191
-
S. O'Brien, J.O. Moore, T.E. Boyd, L.M. Larratt, A. Skotnicki, B. Koziner, A.A. Chanan-Khan, J.F. Seymour, R.G. Bociek, S. Pavletic, and K.R. Rai Randomized phase III trial of fludarabine plus cyclophosphamide with or without oblimersen sodium (Bcl-2 antisense) in patients with relapsed or refractory chronic lymphocytic leukemia J. Clin. Oncol. 25 2007 1114 1120 (Pubitemid 46596764)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.9
, pp. 1114-1120
-
-
O'Brien, S.1
Moore, J.O.2
Boyd, T.E.3
Larratt, L.M.4
Skotnicki, A.5
Koziner, B.6
Chanan-Khan, A.A.7
Seymour, J.F.8
Bociek, R.G.9
Pavletic, S.10
Rai, K.R.11
-
87
-
-
35648973642
-
Targeting BCL-2 family proteins to overcome drug resistance in non-small cell lung cancer
-
DOI 10.1002/ijc.22977
-
E. Wesarg, S. Hoffarth, R. Wiewrodt, M. Kroll, S. Biesterfeld, C. Huber, and M. Schuler Targeting BCL-2 family proteins to overcome drug resistance in non-small cell lung cancer Int. J. Cancer 121 2007 2387 2394 (Pubitemid 350022407)
-
(2007)
International Journal of Cancer
, vol.121
, Issue.11
, pp. 2387-2394
-
-
Wesarg, E.1
Hoffarth, S.2
Wiewrodt, R.3
Kroll, M.4
Biesterfeld, S.5
Huber, C.6
Schuler, M.7
-
88
-
-
10744229243
-
Bcl-2 down-regulation is a novel mechanism of paclitaxel resistance
-
DOI 10.1124/mol.64.1.51
-
C. Ferlini, G. Raspaglio, S. Mozzetti, M. Distefano, F. Filippetti, E. Martinelli, G. Ferrandina, D. Gallo, F.O. Ranelletti, and G. Scambia Bcl-2 down-regulation is a novel mechanism of paclitaxel resistance Mol. Pharmacol. 64 2003 51 58 (Pubitemid 36759817)
-
(2003)
Molecular Pharmacology
, vol.64
, Issue.1
, pp. 51-58
-
-
Ferlini, C.1
Raspaglio, G.2
Mozzetti, S.3
Distefano, M.4
Filippetti, F.5
Martinelli, E.6
Ferrandina, G.7
Gallo, D.8
Oreste Ranelletti, F.9
Scambia, G.10
-
89
-
-
16244366499
-
Bcl-2 overexpression enhances in vitro sensitivity against docetaxel in non-small cell lung cancer
-
Y. Inoue, M. Gika, T. Abiko, T. Oyama, Y. Saitoh, H. Yamazaki, M. Nakamura, Y. Abe, M. Kawamura, and K. Kobayashi Bcl-2 overexpression enhances in vitro sensitivity against docetaxel in non-small cell lung cancer Oncol. Rep. 13 2005 259 264
-
(2005)
Oncol. Rep.
, vol.13
, pp. 259-264
-
-
Inoue, Y.1
Gika, M.2
Abiko, T.3
Oyama, T.4
Saitoh, Y.5
Yamazaki, H.6
Nakamura, M.7
Abe, Y.8
Kawamura, M.9
Kobayashi, K.10
-
90
-
-
0036531791
-
Antisense RNA down-regulation of bcl-xL expression in prostate cancer cells leads to diminished rates of cellular proliferation and resistance to cytotoxic chemotherapeutic agents
-
M. Vilenchik, A.J. Raffo, L. Benimetskaya, D. Shames, and C.A. Stein Antisense RNA down-regulation of bcl-xL expression in prostate cancer cells leads to diminished rates of cellular proliferation and resistance to cytotoxic chemotherapeutic agents Cancer Res. 62 2002 2175 2183 (Pubitemid 34408468)
-
(2002)
Cancer Research
, vol.62
, Issue.7
, pp. 2175-2183
-
-
Vilenchik, M.1
Raffo, A.J.2
Benimetskaya, L.3
Shames, D.4
Stein, C.A.5
-
92
-
-
0034306461
-
P53 is associated with cellular microtubules and is transported to the nucleus by dynein
-
P. Giannakakou, D.L. Sackett, Y. Ward, K.R. Webster, M.V. Blagosklonny, and T. Fojo p53 is associated with cellular microtubules and is transported to the nucleus by dynein Nat. Cell Biol. 2 2000 709 717
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 709-717
-
-
Giannakakou, P.1
Sackett, D.L.2
Ward, Y.3
Webster, K.R.4
Blagosklonny, M.V.5
Fojo, T.6
-
93
-
-
52949107914
-
Patupilone-induced apoptosis is mediated by mitochondrial reactive oxygen species through Bim relocalization to mitochondria
-
N.R. Khawaja, M. Carre, H. Kovacic, M.A. Esteve, and D. Braguer Patupilone-induced apoptosis is mediated by mitochondrial reactive oxygen species through Bim relocalization to mitochondria Mol. Pharmacol. 74 2008 1072 1083
-
(2008)
Mol. Pharmacol.
, vol.74
, pp. 1072-1083
-
-
Khawaja, N.R.1
Carre, M.2
Kovacic, H.3
Esteve, M.A.4
Braguer, D.5
-
94
-
-
0242407074
-
WAF1/CIP1 expression by vinorelbine in androgen-independent prostate cancer cells
-
DOI 10.1038/sj.bjc.6601317
-
X.M. Liu, J.D. Jiang, A.C. Ferrari, D.R. Budman, and L.G. Wang Unique induction of p21(WAF1/CIP1) expression by vinorelbine in androgen-independent prostate cancer cells Br. J. Cancer 89 2003 1566 1573 (Pubitemid 37386616)
-
(2003)
British Journal of Cancer
, vol.89
, Issue.8
, pp. 1566-1573
-
-
Liu, X.M.1
Jiang, J.D.2
Ferrari, A.C.3
Budman, D.R.4
Wang, L.G.5
-
95
-
-
77952303646
-
Griseofulvin stabilizes microtubule dynamics, activates p53 and inhibits the proliferation of MCF-7 cells synergistically with vinblastine
-
K. Rathinasamy, B. Jindal, J. Asthana, P. Singh, P.V. Balaji, and D. Panda Griseofulvin stabilizes microtubule dynamics, activates p53 and inhibits the proliferation of MCF-7 cells synergistically with vinblastine BMC Cancer 10 2010 213
-
(2010)
BMC Cancer
, vol.10
, pp. 213
-
-
Rathinasamy, K.1
Jindal, B.2
Asthana, J.3
Singh, P.4
Balaji, P.V.5
Panda, D.6
-
96
-
-
0028875515
-
Microtubule-active drugs taxol, vinblastine, and nocodazole increase the levels of transcriptionally active p53
-
R.B. Tishler, D.M. Lamppu, S. Park, and B.D. Price Microtubule-active drugs taxol, vinblastine, and nocodazole increase the levels of transcriptionally active p53 Cancer Res. 55 1995 6021 6025
-
(1995)
Cancer Res.
, vol.55
, pp. 6021-6025
-
-
Tishler, R.B.1
Lamppu, D.M.2
Park, S.3
Price, B.D.4
-
97
-
-
77955011172
-
Tau overexpression inhibits cell apoptosis with the mechanisms involving multiple viability-related factors
-
H.H. Wang, H.L. Li, R. Liu, Y. Zhang, K. Liao, Q. Wang, J.Z. Wang, and S.J. Liu Tau overexpression inhibits cell apoptosis with the mechanisms involving multiple viability-related factors J. Alzheimers Dis. 2010 167 179
-
(2010)
J. Alzheimers Dis.
, pp. 167-179
-
-
Wang, H.H.1
Li, H.L.2
Liu, R.3
Zhang, Y.4
Liao, K.5
Wang, Q.6
Wang, J.Z.7
Liu, S.J.8
-
98
-
-
54049104910
-
Low doses of paclitaxel potently induce apoptosis in human retinoblastoma Y79 cells by up-regulating E2F1
-
R. Drago-Ferrante, A. Santulli, R. Di Fiore, M. Giuliano, G. Calvaruso, G. Tesoriere, and R. Vento Low doses of paclitaxel potently induce apoptosis in human retinoblastoma Y79 cells by up-regulating E2F1 Int. J. Oncol. 33 2008 677 687
-
(2008)
Int. J. Oncol.
, vol.33
, pp. 677-687
-
-
Drago-Ferrante, R.1
Santulli, A.2
Di Fiore, R.3
Giuliano, M.4
Calvaruso, G.5
Tesoriere, G.6
Vento, R.7
-
99
-
-
17644421083
-
Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy
-
DOI 10.1016/j.ccr.2005.02.008
-
T.T. Tan, K. Degenhardt, D.A. Nelson, B. Beaudoin, W. Nieves-Neira, P. Bouillet, A. Villunger, J.M. Adams, and E. White Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy Cancer Cell 7 2005 227 238 (Pubitemid 40568682)
-
(2005)
Cancer Cell
, vol.7
, Issue.3
, pp. 227-238
-
-
Tan, T.-T.1
Degenhardt, K.2
Nelson, D.A.3
Beaudoin, B.4
Nieves-Neira, W.5
Bouillet, P.6
Villunger, A.7
Adams, J.M.8
White, E.9
-
100
-
-
2542482495
-
Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus
-
DOI 10.1074/jbc.M402223200
-
M.D. Galigniana, J.M. Harrell, H.M. O'Hagen, M. Ljungman, and W.B. Pratt Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus J. Biol. Chem. 279 2004 22483 22489 (Pubitemid 38679447)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.21
, pp. 22483-22489
-
-
Galigniana, M.D.1
Harrell, J.M.2
O'Hagen, H.M.3
Ljungman, M.4
Pratt, W.B.5
-
101
-
-
56549120027
-
Kinetic stabilization of microtubule dynamic instability by benomyl increases the nuclear transport of p53
-
K. Rathinasamy, and D. Panda Kinetic stabilization of microtubule dynamic instability by benomyl increases the nuclear transport of p53 Biochem. Pharmacol. 76 2008 1669 1680
-
(2008)
Biochem. Pharmacol.
, vol.76
, pp. 1669-1680
-
-
Rathinasamy, K.1
Panda, D.2
-
102
-
-
0031593748
-
The relationship between Bcl2, Bax and p53: Consequences for cell cycle progression and cell death
-
A. Basu, and S. Haldar The relationship between BcI2, Bax and p53: consequences for cell cycle progression and cell death Mol. Hum. Reprod. 4 1998 1099 1109 (Pubitemid 28552792)
-
(1998)
Molecular Human Reproduction
, vol.4
, Issue.12
, pp. 1099-1109
-
-
Basu, A.1
Haldar, S.2
-
103
-
-
0035843156
-
Negative regulation of bcl-2 expression by p53 in hematopoietic cells
-
DOI 10.1038/sj.onc.1204067
-
Y. Wu, J.W. Mehew, C.A. Heckman, M. Arcinas, and L.M. Boxer Negative regulation of bcl-2 expression by p53 in hematopoietic cells Oncogene 20 2001 240 251 (Pubitemid 32150269)
-
(2001)
Oncogene
, vol.20
, Issue.2
, pp. 240-251
-
-
Wu, Y.1
Mehew, J.W.2
Heckman, C.A.3
Arcinas, M.4
Boxer, L.M.5
-
104
-
-
70249117438
-
Transcriptional down-regulation of Bcl-2 by vinorelbine: Identification of a novel binding site of p53 on Bcl-2 promoter
-
V. Bourgarel-Rey, A. Savry, G. Hua, M. Carre, C. Bressin, C. Chacon, J. Imbert, D. Braguer, and Y. Barra Transcriptional down-regulation of Bcl-2 by vinorelbine: identification of a novel binding site of p53 on Bcl-2 promoter Biochem. Pharmacol. 78 2009 1148 1156
-
(2009)
Biochem. Pharmacol.
, vol.78
, pp. 1148-1156
-
-
Bourgarel-Rey, V.1
Savry, A.2
Hua, G.3
Carre, M.4
Bressin, C.5
Chacon, C.6
Imbert, J.7
Braguer, D.8
Barra, Y.9
-
105
-
-
0035963277
-
Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: Molecular determinants of paclitaxel-induced cytotoxicity
-
DOI 10.1038/sj.onc.1204487
-
P. Giannakakou, R. Robey, T. Fojo, and M.V. Blagosklonny Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity Oncogene 20 2001 3806 3813 (Pubitemid 32646191)
-
(2001)
Oncogene
, vol.20
, Issue.29
, pp. 3806-3813
-
-
Giannakakou, P.1
Robey, R.2
Fojo, T.3
Blagosklonny, M.V.4
-
106
-
-
0035949470
-
Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals
-
DOI 10.1073/pnas.201208798
-
J. Han, C. Flemington, A.B. Houghton, Z. Gu, G.P. Zambetti, R.J. Lutz, L. Zhu, and T. Chittenden Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals Proc. Natl Acad. Sci. USA 98 2001 11318 11323 (Pubitemid 32928726)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.20
, pp. 11318-11323
-
-
Han, J.-W.1
Flemington, C.2
Houghton, A.B.3
Gu, Z.4
Zambetti, G.P.5
Lutz, R.J.6
Zhu, L.7
Chittenden, T.8
-
107
-
-
0035265686
-
PUMA, a novel proapoptotic gene, is induced by p53
-
DOI 10.1016/S1097-2765(01)00214-3
-
K. Nakano, and K.H. Vousden PUMA, a novel proapoptotic gene, is induced by p53 Mol. Cell 7 2001 683 694 (Pubitemid 32706359)
-
(2001)
Molecular Cell
, vol.7
, Issue.3
, pp. 683-694
-
-
Nakano, K.1
Vousden, K.H.2
-
108
-
-
27144488229
-
Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol γ
-
DOI 10.1038/sj.emboj.7600819, PII 7600819
-
G. Achanta, R. Sasaki, L. Feng, J.S. Carew, W. Lu, H. Pelicano, M.J. Keating, and P. Huang Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma EMBO J. 24 2005 3482 3492 (Pubitemid 41486785)
-
(2005)
EMBO Journal
, vol.24
, Issue.19
, pp. 3482-3492
-
-
Achanta, G.1
Sasaki, R.2
Feng, L.3
Carew, J.S.4
Lu, W.5
Pelicano, H.6
Keating, M.J.7
Huang, P.8
-
109
-
-
17144428550
-
Stress-induced p53 runs a direct mitochondrial death program: Its role in physiologic and pathophysiologic stress responses in vivo
-
S. Erster, and U.M. Moll Stress-induced p53 runs a direct mitochondrial death program: its role in physiologic and pathophysiologic stress responses in vivo Cell Cycle 3 2004 1492 1495 (Pubitemid 40521398)
-
(2004)
Cell Cycle
, vol.3
, Issue.12
, pp. 1492-1495
-
-
Erster, S.1
Moll, U.M.2
-
110
-
-
0037349289
-
P53 has a direct apoptogenic role at the mitochondria
-
DOI 10.1016/S1097-2765(03)00050-9
-
M. Mihara, S. Erster, A. Zaika, O. Petrenko, T. Chittenden, P. Pancoska, and U.M. Moll p53 has a direct apoptogenic role at the mitochondria Mol. Cell 11 2003 577 590 (Pubitemid 36385115)
-
(2003)
Molecular Cell
, vol.11
, Issue.3
, pp. 577-590
-
-
Mihara, M.1
Erster, S.2
Zaika, A.3
Petrenko, O.4
Chittenden, T.5
Pancoska, P.6
Moll, U.M.7
-
111
-
-
0035910385
-
Hypoxia death stimulus induces translocation of p53 protein to mitochondria - Detection by immunofluorescence on whole cells
-
DOI 10.1016/S0014-5793(00)02368-1, PII S0014579300023681
-
C. Sansome, A. Zaika, N.D. Marchenko, and U.M. Moll Hypoxia death stimulus induces translocation of p53 protein to mitochondria. Detection by immunofluorescence on whole cells FEBS Lett. 488 2001 110 115 (Pubitemid 32103581)
-
(2001)
FEBS Letters
, vol.488
, Issue.3
, pp. 110-115
-
-
Sansome, C.1
Zaika, A.2
Marchenko, N.D.3
Moll, U.M.4
-
112
-
-
0034717014
-
Death signal-induced localization of p53 protein to mitochondria: A potential role in apoptotic signaling
-
DOI 10.1074/jbc.275.21.16202
-
N.D. Marchenko, A. Zaika, and U.M. Moll Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling J. Biol. Chem. 275 2000 16202 16212 (Pubitemid 30366932)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.21
, pp. 16202-16212
-
-
Marchenko, N.D.1
Zaika, A.2
Moll, U.M.3
-
113
-
-
18144382261
-
P53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase
-
DOI 10.1158/0008-5472.CAN-04-3835
-
Y. Zhao, L. Chaiswing, J.M. Velez, I. Batinic-Haberle, N.H. Colburn, T.D. Oberley, and D.K. St Clair p53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase Cancer Res. 65 2005 3745 3750 (Pubitemid 40616352)
-
(2005)
Cancer Research
, vol.65
, Issue.9
, pp. 3745-3750
-
-
Zhao, Y.1
Chaiswing, L.2
Velez, J.M.3
Batinic-Haberle, I.4
Colburn, N.H.5
Oberley, T.D.6
St. Clair, D.K.7
-
114
-
-
65949083750
-
Cytoplasmic functions of the tumour suppressor p53
-
D.R. Green, and G. Kroemer Cytoplasmic functions of the tumour suppressor p53 Nature 458 2009 1127 1130
-
(2009)
Nature
, vol.458
, pp. 1127-1130
-
-
Green, D.R.1
Kroemer, G.2
-
115
-
-
33747620737
-
Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation
-
DOI 10.1038/nchembio809, PII NCHEMBIO809
-
E. Strom, S. Sathe, P.G. Komarov, O.B. Chernova, I. Pavlovska, I. Shyshynova, D.A. Bosykh, L.G. Burdelya, R.M. Macklis, R. Skaliter, E.A. Komarova, and A.V. Gudkov Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation Nat. Chem. Biol. 2 2006 474 479 (Pubitemid 44266309)
-
(2006)
Nature Chemical Biology
, vol.2
, Issue.9
, pp. 474-479
-
-
Strom, E.1
Sathe, S.2
Komarov, P.G.3
Chernova, O.B.4
Pavlovska, I.5
Shyshynova, I.6
Bosykh, D.A.7
Burdelya, L.G.8
Macklis, R.M.9
Skaliter, R.10
Komarova, E.A.11
Gudkov, A.V.12
-
116
-
-
33748316625
-
TRAIL receptor-mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality
-
DOI 10.1172/JCI27726
-
N. Corazza, S. Jakob, C. Schaer, S. Frese, A. Keogh, D. Stroka, D. Kassahn, R. Torgler, C. Mueller, P. Schneider, and T. Brunner TRAIL receptor-mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality J. Clin. Invest. 116 2006 2493 2499 (Pubitemid 44330148)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.9
, pp. 2493-2499
-
-
Corazza, N.1
Jakob, S.2
Schaer, C.3
Frese, S.4
Keogh, A.5
Stroka, D.6
Kassahn, D.7
Torgler, R.8
Mueller, C.9
Schneider, P.10
Brunner, T.11
-
117
-
-
35648949422
-
BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations
-
D.B. Costa, B. Halmos, A. Kumar, S.T. Schumer, M.S. Huberman, T.J. Boggon, D.G. Tenen, and S. Kobayashi BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations PLoS Med. 4 2007 1669 1679 discussion 1680
-
(2007)
PLoS Med.
, vol.4
, pp. 1669-1679
-
-
Costa, D.B.1
Halmos, B.2
Kumar, A.3
Schumer, S.T.4
Huberman, M.S.5
Boggon, T.J.6
Tenen, D.G.7
Kobayashi, S.8
-
118
-
-
33749510073
-
+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic
-
DOI 10.1073/pnas.0606176103
-
J. Kuroda, H. Puthalakath, M.S. Cragg, P.N. Kelly, P. Bouillet, D.C. Huang, S. Kimura, O.G. Ottmann, B.J. Druker, A. Villunger, A.W. Roberts, and A. Strasser Bim and Bad mediate imatinib-induced killing of Bcr/Abl + leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic Proc. Natl Acad. Sci. USA 103 2006 14907 14912 (Pubitemid 44527827)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.40
, pp. 14907-14912
-
-
Kuroda, J.1
Puthalakath, H.2
Cragg, M.S.3
Kelly, P.N.4
Bouillet, P.5
Huang, D.C.S.6
Kimura, S.7
Ottmann, O.G.8
Druker, B.J.9
Villunger, A.10
Roberts, A.W.11
Strasser, A.12
-
119
-
-
33746391136
-
P38-MAP kinase activation followed by BIM induction is essential for glucocorticoid-induced apoptosis in lymphoblastic leukemia cells
-
DOI 10.1016/j.febslet.2006.05.031, PII S0014579306006235
-
J. Lu, B. Quearry, and H. Harada p38-MAP kinase activation followed by BIM induction is essential for glucocorticoid-induced apoptosis in lymphoblastic leukemia cells FEBS Lett. 580 2006 3539 3544 (Pubitemid 44208999)
-
(2006)
FEBS Letters
, vol.580
, Issue.14
, pp. 3539-3544
-
-
Lu, J.1
Quearry, B.2
Harada, H.3
-
120
-
-
64049095817
-
BH3-only protein Bim more critical than Puma in tyrosine kinase inhibitor-induced apoptosis of human leukemic cells and transduced hematopoietic progenitors carrying oncogenic FLT3
-
A. Nordigarden, M. Kraft, P. Eliasson, V. Labi, E.W. Lam, A. Villunger, and J.I. Jonsson BH3-only protein Bim more critical than Puma in tyrosine kinase inhibitor-induced apoptosis of human leukemic cells and transduced hematopoietic progenitors carrying oncogenic FLT3 Blood 113 2009 2302 2311
-
(2009)
Blood
, vol.113
, pp. 2302-2311
-
-
Nordigarden, A.1
Kraft, M.2
Eliasson, P.3
Labi, V.4
Lam, E.W.5
Villunger, A.6
Jonsson, J.I.7
-
121
-
-
27544446991
-
Life in the balance: How BH3-only proteins induce apoptosis
-
DOI 10.1016/j.ceb.2005.10.001, PII S095506740500150X
-
S.N. Willis, and J.M. Adams Life in the balance: how BH3-only proteins induce apoptosis Curr. Opin. Cell Biol. 17 2005 617 625 (Pubitemid 41540411)
-
(2005)
Current Opinion in Cell Biology
, vol.17
, Issue.6
, pp. 617-625
-
-
Willis, S.N.1
Adams, J.M.2
-
122
-
-
10744230034
-
FoxO3a Transcriptional Regulation of Bim Controls Apoptosis in Paclitaxel-treated Breast Cancer Cell Lines
-
DOI 10.1074/jbc.M309523200
-
A. Sunters, S. Fernandez de Mattos, M. Stahl, J.J. Brosens, G. Zoumpoulidou, C.A. Saunders, P.J. Coffer, R.H. Medema, R.C. Coombes, and E.W. Lam FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines J. Biol. Chem. 278 2003 49795 49805 (Pubitemid 37548813)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.50
, pp. 49795-49805
-
-
Sunters, A.1
Fernandez De Mattos, S.2
Stahl, M.3
Brosens, J.J.4
Zoumpoulidou, G.5
Saunders, C.A.6
Coffer, P.J.7
Medema, R.H.8
Coombes, R.C.9
Lam, E.W.-F.10
-
123
-
-
79955578148
-
RhoA and diaphanous-related homolog 1 mediate adrenocorticotropin- stimulated cortisol biosynthesis by regulating mitochondrial trafficking
-
D. Li, and M.B. Sewer RhoA and diaphanous-related homolog 1 mediate adrenocorticotropin-stimulated cortisol biosynthesis by regulating mitochondrial trafficking Endocrinology 2010 247 258
-
(2010)
Endocrinology
, pp. 247-258
-
-
Li, D.1
Sewer, M.B.2
-
124
-
-
0033607506
-
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
-
P. Bouillet, D. Metcalf, D.C. Huang, D.M. Tarlinton, T.W. Kay, F. Kontgen, J.M. Adams, and A. Strasser Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity Science 286 1999 1735 1738 (Pubitemid 129515880)
-
(1999)
Science
, vol.286
, Issue.5445
, pp. 1735-1738
-
-
Bouillet, P.1
Metcalf, D.2
Huang, D.C.S.3
Tarlinton, D.M.4
Kay, T.W.H.5
Kontgen, F.6
Adams, J.M.7
Strasser, A.8
-
126
-
-
0033104996
-
The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex
-
DOI 10.1016/S1097-2765(00)80456-6
-
H. Puthalakath, D.C. Huang, L.A. O'Reilly, S.M. King, and A. Strasser The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex Mol. Cell 3 1999 287 296 (Pubitemid 29290669)
-
(1999)
Molecular Cell
, vol.3
, Issue.3
, pp. 287-296
-
-
Puthalakath, H.1
Huang, D.C.S.2
O'Reilly, L.A.3
King, S.M.4
Strasser, A.5
-
127
-
-
12244304872
-
HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim
-
DOI 10.1093/emboj/cdf683
-
D. Chen, M. Wang, S. Zhou, and Q. Zhou HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim EMBO J. 21 2002 6801 6810 (Pubitemid 36014552)
-
(2002)
EMBO Journal
, vol.21
, Issue.24
, pp. 6801-6810
-
-
Chen, D.1
Wang, M.2
Zhou, S.3
Zhou, Q.4
-
128
-
-
33749565548
-
A novel plant toxin, persin, with in vivo activity in the mammary gland, induces Bim-dependent apoptosis in human breast cancer cells
-
DOI 10.1158/1535-7163.MCT-06-0170
-
A.J. Butt, C.G. Roberts, A.A. Seawright, P.B. Oelrichs, J.K. Macleod, T.Y. Liaw, M. Kavallaris, T.J. Somers-Edgar, G.M. Lehrbach, C.K. Watts, and R.L. Sutherland A novel plant toxin, persin, with in vivo activity in the mammary gland, induces Bim-dependent apoptosis in human breast cancer cells Mol. Cancer Ther. 5 2006 2300 2309 (Pubitemid 44530467)
-
(2006)
Molecular Cancer Therapeutics
, vol.5
, Issue.9
, pp. 2300-2309
-
-
Butt, A.J.1
Roberts, C.G.2
Seawright, A.A.3
Oelrichs, P.B.4
MacLeod, J.K.5
Liaw, T.Y.E.6
Kavallaris, M.7
Somers-Edgar, T.J.8
Lehrbach, G.M.9
Watts, C.K.10
Sutherland, R.L.11
-
129
-
-
42149153777
-
The tubulin-depolymerising agent combretastatin-4 induces ectopic aster assembly and mitotic catastrophe in lung cancer cells H460
-
C. Cenciarelli, C. Tanzarella, I. Vitale, C. Pisano, P. Crateri, S. Meschini, G. Arancia, and A. Antoccia The tubulin-depolymerising agent combretastatin-4 induces ectopic aster assembly and mitotic catastrophe in lung cancer cells H460 Apoptosis 13 2008 659 669
-
(2008)
Apoptosis
, vol.13
, pp. 659-669
-
-
Cenciarelli, C.1
Tanzarella, C.2
Vitale, I.3
Pisano, C.4
Crateri, P.5
Meschini, S.6
Arancia, G.7
Antoccia, A.8
-
130
-
-
70350212784
-
BH3-only proteins Mcl-1 and Bim as well as endonuclease G are targeted in spongistatin 1-induced apoptosis in breast cancer cells
-
U.M. Schneiders, L. Schyschka, A. Rudy, and A.M. Vollmar BH3-only proteins Mcl-1 and Bim as well as endonuclease G are targeted in spongistatin 1-induced apoptosis in breast cancer cells Mol. Cancer Ther. 8 2009 2914 2925
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 2914-2925
-
-
Schneiders, U.M.1
Schyschka, L.2
Rudy, A.3
Vollmar, A.M.4
-
132
-
-
21044444012
-
Gadd45a expression induces bim dissociation from the cytoskeleton and translocation to mitochondria
-
DOI 10.1128/MCB.25.11.4488-4500.2005
-
T. Tong, J. Ji, S. Jin, X. Li, W. Fan, Y. Song, M. Wang, Z. Liu, M. Wu, and Q. Zhan Gadd45a expression induces Bim dissociation from the cytoskeleton and translocation to mitochondria Mol. Cell. Biol. 25 2005 4488 4500 (Pubitemid 40705755)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.11
, pp. 4488-4500
-
-
Tong, T.1
Ji, J.2
Jin, S.3
Li, X.4
Fan, W.5
Song, Y.6
Wang, M.7
Liu, Z.8
Wu, M.9
Zhan, Q.10
-
133
-
-
33646517942
-
Accumulation of hydrogen peroxide is an early and crucial step for paclitaxel-induced cancer cell death both in vitro and in vivo
-
J. Alexandre, F. Batteux, C. Nicco, C. Chereau, A. Laurent, L. Guillevin, B. Weill, and F. Goldwasser Accumulation of hydrogen peroxide is an early and crucial step for paclitaxel-induced cancer cell death both in vitro and in vivo Int. J. Cancer 119 2006 41 48
-
(2006)
Int. J. Cancer
, vol.119
, pp. 41-48
-
-
Alexandre, J.1
Batteux, F.2
Nicco, C.3
Chereau, C.4
Laurent, A.5
Guillevin, L.6
Weill, B.7
Goldwasser, F.8
-
134
-
-
33144481896
-
Contribution of reactive oxygen species and caspase-3 to apoptosis and attenuated ICAM-1 expression by paclitaxel-treated MDA-MB-435 breast carcinoma cells
-
H. Fawcett, J.S. Mader, M. Robichaud, C. Giacomantonio, and D.W. Hoskin Contribution of reactive oxygen species and caspase-3 to apoptosis and attenuated ICAM-1 expression by paclitaxel-treated MDA-MB-435 breast carcinoma cells Int. J. Oncol. 27 2005 1717 1726
-
(2005)
Int. J. Oncol.
, vol.27
, pp. 1717-1726
-
-
Fawcett, H.1
Mader, J.S.2
Robichaud, M.3
Giacomantonio, C.4
Hoskin, D.W.5
-
135
-
-
0034283773
-
Comparison of 2-methoxyestradiol-induced, docetaxel-induced, and paclitaxel-induced apoptosis in hepatoma cells and its correlation with reactive oxygen species
-
H.L. Lin, T.Y. Liu, G.Y. Chau, W.Y. Lui, and C.W. Chi Comparison of 2-methoxyestradiol-induced, docetaxel-induced, and paclitaxel-induced apoptosis in hepatoma cells and its correlation with reactive oxygen species Cancer 89 2000 983 994
-
(2000)
Cancer
, vol.89
, pp. 983-994
-
-
Lin, H.L.1
Liu, T.Y.2
Chau, G.Y.3
Lui, W.Y.4
Chi, C.W.5
-
136
-
-
0035882351
-
Direct effect of Taxol on free radical formation and mitochondrial permeability transition
-
DOI 10.1016/S0891-5849(01)00616-5, PII S0891584901006165
-
G. Varbiro, B. Veres, F. Gallyas Jr., and B. Sumegi Direct effect of Taxol on free radical formation and mitochondrial permeability transition Free Radic. Biol. Med. 31 2001 548 558 (Pubitemid 32728442)
-
(2001)
Free Radical Biology and Medicine
, vol.31
, Issue.4
, pp. 548-558
-
-
Varbiro, G.1
Veres, B.2
Gallyas Jr., F.3
Sumegi, B.4
-
138
-
-
0034307316
-
Paclitaxel induces release of cytochrome c from mitochondria isolated from human neuroblastoma cells
-
N. Andre, D. Braguer, G. Brasseur, A. Goncalves, D. Lemesle-Meunier, S. Guise, M.A. Jordan, and C. Briand Paclitaxel induces release of cytochrome c from mitochondria isolated from human neuroblastoma cells Cancer Res. 60 2000 5349 5353
-
(2000)
Cancer Res.
, vol.60
, pp. 5349-5353
-
-
Andre, N.1
Braguer, D.2
Brasseur, G.3
Goncalves, A.4
Lemesle-Meunier, D.5
Guise, S.6
Jordan, M.A.7
Briand, C.8
-
139
-
-
12844273565
-
2+ release
-
DOI 10.1074/jbc.M409819200
-
S.L. Mironov, M.V. Ivannikov, and M. Johansson [Ca2+]i signaling between mitochondria and endoplasmic reticulum in neurons is regulated by microtubules. From mitochondrial permeability transition pore to Ca2+-induced Ca2+ release J. Biol. Chem. 280 2005 715 721 (Pubitemid 40165039)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.1
, pp. 715-721
-
-
Mironov, S.L.1
Ivannikov, M.V.2
Johansson, M.3
-
140
-
-
0037155258
-
Paclitaxel affects cytosolic calcium signals by opening the mitochondrial permeability transition pore
-
DOI 10.1074/jbc.M106802200
-
J.F. Kidd, M.F. Pilkington, M.J. Schell, K.E. Fogarty, J.N. Skepper, C.W. Taylor, and P. Thorn Paclitaxel affects cytosolic calcium signals by opening the mitochondrial permeability transition pore J. Biol. Chem. 277 2002 6504 6510 (Pubitemid 34968448)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.8
, pp. 6504-6510
-
-
Kidd, J.F.1
Pilkington, M.F.2
Schell, M.J.3
Fogarty, K.E.4
Skepper, J.N.5
Taylor, C.W.6
Thorn, P.7
-
141
-
-
49149124239
-
Nanocarrier-assisted sub-cellular targeting to the site of mitochondria improves the pro-apoptotic activity of paclitaxel
-
G.G. D'Souza, S.M. Cheng, S.V. Boddapati, R.W. Horobin, and V. Weissig Nanocarrier-assisted sub-cellular targeting to the site of mitochondria improves the pro-apoptotic activity of paclitaxel J. Drug Target. 16 2008 578 585
-
(2008)
J. Drug Target.
, vol.16
, pp. 578-585
-
-
D'Souza, G.G.1
Cheng, S.M.2
Boddapati, S.V.3
Horobin, R.W.4
Weissig, V.5
-
142
-
-
0037072776
-
Tubulin is an inherent component of mitochondrial membranes that interacts with the voltage-dependent anion channel
-
M. Carre, N. Andre, G. Carles, H. Borghi, L. Brichese, C. Briand, and D. Braguer Tubulin is an inherent component of mitochondrial membranes that interacts with the voltage-dependent anion channel J. Biol. Chem. 277 2002 33664 33669
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 33664-33669
-
-
Carre, M.1
Andre, N.2
Carles, G.3
Borghi, H.4
Brichese, L.5
Briand, C.6
Braguer, D.7
-
143
-
-
0037094447
-
Involvement of microtubules and mitochondria in the antagonism of arsenic trioxide on paclitaxel-induced apoptosis
-
DOI 10.1016/S0006-2952(02)00922-X, PII S000629520200922X
-
M. Carre, G. Carles, N. Andre, S. Douillard, J. Ciccolini, C. Briand, and D. Braguer Involvement of microtubules and mitochondria in the antagonism of arsenic trioxide on paclitaxel-induced apoptosis Biochem. Pharmacol. 63 2002 1831 1842 (Pubitemid 34603447)
-
(2002)
Biochemical Pharmacology
, vol.63
, Issue.10
, pp. 1831-1842
-
-
Carre, M.1
Carles, G.2
Andre, N.3
Douillard, S.4
Ciccolini, J.5
Briand, C.6
Braguer, D.7
-
144
-
-
51049119252
-
Proteomic characterization of cytoskeletal and mitochondrial class III beta-tubulin
-
L. Cicchillitti, R. Penci, M. Di Michele, F. Filippetti, D. Rotilio, M.B. Donati, G. Scambia, and C. Ferlini Proteomic characterization of cytoskeletal and mitochondrial class III beta-tubulin Mol. Cancer Ther. 7 2008 2070 2079
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 2070-2079
-
-
Cicchillitti, L.1
Penci, R.2
Di Michele, M.3
Filippetti, F.4
Rotilio, D.5
Donati, M.B.6
Scambia, G.7
Ferlini, C.8
-
145
-
-
57749084634
-
Tubulin binding blocks mitochondrial voltage-dependent anion channel and regulates respiration
-
T.K. Rostovtseva, K.L. Sheldon, E. Hassanzadeh, C. Monge, V. Saks, S.M. Bezrukov, and D.L. Sackett Tubulin binding blocks mitochondrial voltage-dependent anion channel and regulates respiration Proc. Natl Acad. Sci. USA 105 2008 18746 18751
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 18746-18751
-
-
Rostovtseva, T.K.1
Sheldon, K.L.2
Hassanzadeh, E.3
Monge, C.4
Saks, V.5
Bezrukov, S.M.6
Sackett, D.L.7
-
146
-
-
0030576917
-
Microtubule-active drugs suppress the closure of the permeability transition pore in tumour mitochondria
-
DOI 10.1016/0014-5793(96)00875-7
-
Y.V. Evtodienko, V.V. Teplova, S.S. Sidash, F. Ichas, and J.P. Mazat Microtubule-active drugs suppress the closure of the permeability transition pore in tumour mitochondria FEBS Lett. 393 1996 86 88 (Pubitemid 26298235)
-
(1996)
FEBS Letters
, vol.393
, Issue.1
, pp. 86-88
-
-
Evtodienko, Y.V.1
Teplova, V.V.2
Sidash, S.S.3
Ichas, F.4
Mazat, J.-P.5
-
147
-
-
0033534641
-
Screening of a library of phage-displayed peptides identifies human Bcl-2 as a Taxol-binding protein
-
DOI 10.1006/jmbi.1998.2303
-
D.J. Rodi, R.W. Janes, H.J. Sanganee, R.A. Holton, B.A. Wallace, and L. Makowski Screening of a library of phage-displayed peptides identifies human bcl-2 as a taxol-binding protein J. Mol. Biol. 285 1999 197 203 (Pubitemid 29034037)
-
(1999)
Journal of Molecular Biology
, vol.285
, Issue.1
, pp. 197-203
-
-
Rodi, D.J.1
Janes, R.W.2
Sanganee, H.J.3
Holton, R.A.4
Wallace, B.A.5
Makowski, L.6
-
148
-
-
0034434428
-
A model for the interaction of paclitaxel with the Bcl-2 loop domain: A chemical approach to induce conformation-dependent phosphorylation
-
J.H. Wu, G. Batist, and L.O. Zamir A model for the interaction of paclitaxel with the Bcl-2 loop domain: a chemical approach to induce conformation-dependent phosphorylation Anticancer Drug Des. 15 2000 441 446 (Pubitemid 32762370)
-
(2000)
Anti-Cancer Drug Design
, vol.15
, Issue.6
, pp. 441-446
-
-
Jian Hui Wu1
Batist, G.2
Zamir, L.O.3
-
149
-
-
70149101801
-
Paclitaxel directly binds to Bcl-2 and functionally mimics activity of Nur77
-
C. Ferlini, L. Cicchillitti, G. Raspaglio, S. Bartollino, S. Cimitan, C. Bertucci, S. Mozzetti, D. Gallo, M. Persico, C. Fattorusso, G. Campiani, and G. Scambia Paclitaxel directly binds to Bcl-2 and functionally mimics activity of Nur77 Cancer Res. 69 2009 6906 6914
-
(2009)
Cancer Res.
, vol.69
, pp. 6906-6914
-
-
Ferlini, C.1
Cicchillitti, L.2
Raspaglio, G.3
Bartollino, S.4
Cimitan, S.5
Bertucci, C.6
Mozzetti, S.7
Gallo, D.8
Persico, M.9
Fattorusso, C.10
Campiani, G.11
Scambia, G.12
-
150
-
-
31444434855
-
Direct interaction of Bcl-2 proteins with tubulin
-
DOI 10.1016/j.bbrc.2005.12.201, PII S0006291X06000519
-
L. Knipling, and J. Wolff Direct interaction of Bcl-2 proteins with tubulin Biochem. Biophys. Res. Commun. 341 2006 433 439 (Pubitemid 43152123)
-
(2006)
Biochemical and Biophysical Research Communications
, vol.341
, Issue.2
, pp. 433-439
-
-
Knipling, L.1
Wolff, J.2
-
151
-
-
74949132242
-
Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium
-
J.W. Smyth, T.T. Hong, D. Gao, J.M. Vogan, B.C. Jensen, T.S. Fong, P.C. Simpson, D.Y. Stainier, N.C. Chi, and R.M. Shaw Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium J. Clin. Invest. 120 2010 266 279
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 266-279
-
-
Smyth, J.W.1
Hong, T.T.2
Gao, D.3
Vogan, J.M.4
Jensen, B.C.5
Fong, T.S.6
Simpson, P.C.7
Stainier, D.Y.8
Chi, N.C.9
Shaw, R.M.10
-
152
-
-
61449190676
-
Central and peripheral nervous system toxicity of common chemotherapeutic agents
-
C. Sioka, and A.P. Kyritsis Central and peripheral nervous system toxicity of common chemotherapeutic agents Cancer Chemother. Pharmacol. 63 2009 761 767
-
(2009)
Cancer Chemother. Pharmacol.
, vol.63
, pp. 761-767
-
-
Sioka, C.1
Kyritsis, A.P.2
-
153
-
-
45949131693
-
Chemotherapy-induced peripheral neuropathy: Prevention and treatment strategies
-
S. Wolf, D. Barton, L. Kottschade, A. Grothey, and C. Loprinzi Chemotherapy-induced peripheral neuropathy: prevention and treatment strategies Eur. J. Cancer 44 2008 1507 1515
-
(2008)
Eur. J. Cancer
, vol.44
, pp. 1507-1515
-
-
Wolf, S.1
Barton, D.2
Kottschade, L.3
Grothey, A.4
Loprinzi, C.5
-
154
-
-
32244438054
-
Diagnosis, management, and evaluation of chemotherapy-induced peripheral neuropathy
-
DOI 10.1053/j.seminoncol.2005.12.010, PII S0093775405004938, Toxicity of Chemotherapy - The Last Decade
-
F.H. Hausheer, R.L. Schilsky, S. Bain, E.J. Berghorn, and F. Lieberman Diagnosis, management, and evaluation of chemotherapy-induced peripheral neuropathy Semin. Oncol. 33 2006 15 49 (Pubitemid 43214485)
-
(2006)
Seminars in Oncology
, vol.33
, Issue.1
, pp. 15-49
-
-
Hausheer, F.H.1
Schilsky, R.L.2
Bain, S.3
Berghorn, E.J.4
Lieberman, F.5
-
155
-
-
70349446343
-
Targeting neuroprotection as an alternative approach to preventing and treating neuropathic pain
-
T. Bordet, and R.M. Pruss Targeting neuroprotection as an alternative approach to preventing and treating neuropathic pain Neurotherapeutics 6 2009 648 662
-
(2009)
Neurotherapeutics
, vol.6
, pp. 648-662
-
-
Bordet, T.1
Pruss, R.M.2
-
156
-
-
61849097298
-
Therapy of chemotherapy-induced peripheral neuropathy
-
T.J. Kaley, and L.M. Deangelis Therapy of chemotherapy-induced peripheral neuropathy Br. J. Haematol. 145 2009 3 14
-
(2009)
Br. J. Haematol.
, vol.145
, pp. 3-14
-
-
Kaley, T.J.1
Deangelis, L.M.2
-
157
-
-
70349446342
-
Animal models of chemotherapy-evoked painful peripheral neuropathies
-
N. Authier, D. Balayssac, F. Marchand, B. Ling, A. Zangarelli, J. Descoeur, F. Coudore, E. Bourinet, and A. Eschalier Animal models of chemotherapy-evoked painful peripheral neuropathies Neurotherapeutics 6 2009 620 629
-
(2009)
Neurotherapeutics
, vol.6
, pp. 620-629
-
-
Authier, N.1
Balayssac, D.2
Marchand, F.3
Ling, B.4
Zangarelli, A.5
Descoeur, J.6
Coudore, F.7
Bourinet, E.8
Eschalier, A.9
-
158
-
-
0032527105
-
Microtubule disorientation and axonal swelling in unmyelinated sensory axons during vincristine-induced painful neuropathy in rat
-
DOI 10.1002/(SICI)1096-9861(19980615)395:4<481::AID-CNE5>3.0.CO;2-Y
-
K.D. Tanner, J.D. Levine, and K.S. Topp Microtubule disorientation and axonal swelling in unmyelinated sensory axons during vincristine-induced painful neuropathy in rat J. Comp. Neurol. 395 1998 481 492 (Pubitemid 28226093)
-
(1998)
Journal of Comparative Neurology
, vol.395
, Issue.4
, pp. 481-492
-
-
Tanner, K.D.1
Levine, J.D.2
Topp, K.S.3
-
159
-
-
0034605376
-
Damage to the cytoskeleton of large diameter sensory neurons and myelinated axons in vincristine-induced painful peripheral neuropathy in the rat
-
K.S. Topp, K.D. Tanner, and J.D. Levine Damage to the cytoskeleton of large diameter sensory neurons and myelinated axons in vincristine-induced painful peripheral neuropathy in the rat J. Comp. Neurol. 424 2000 563 576 (Pubitemid 30643051)
-
(2000)
Journal of Comparative Neurology
, vol.424
, Issue.4
, pp. 563-576
-
-
Topp, K.S.1
Tanner, K.D.2
Levine, J.D.3
-
160
-
-
33646586688
-
Studies of peripheral sensory nerves in paclitaxel-induced painful peripheral neuropathy: Evidence for mitochondrial dysfunction
-
DOI 10.1016/j.pain.2006.01.037, PII S0304395906000637
-
S.J. Flatters, and G.J. Bennett Studies of peripheral sensory nerves in paclitaxel-induced painful peripheral neuropathy: evidence for mitochondrial dysfunction Pain 122 2006 245 257 (Pubitemid 43729476)
-
(2006)
Pain
, vol.122
, Issue.3
, pp. 245-257
-
-
Flatters, S.J.L.1
Bennett, G.J.2
-
161
-
-
39249083334
-
Prevention of paclitaxel-evoked painful peripheral neuropathy by acetyl-l-carnitine: Effects on axonal mitochondria, sensory nerve fiber terminal arbors, and cutaneous Langerhans cells
-
H.W. Jin, S.J. Flatters, W.H. Xiao, H.L. Mulhern, and G.J. Bennett Prevention of paclitaxel-evoked painful peripheral neuropathy by acetyl-l-carnitine: effects on axonal mitochondria, sensory nerve fiber terminal arbors, and cutaneous Langerhans cells Exp. Neurol. 210 2008 229 237
-
(2008)
Exp. Neurol.
, vol.210
, pp. 229-237
-
-
Jin, H.W.1
Flatters, S.J.2
Xiao, W.H.3
Mulhern, H.L.4
Bennett, G.J.5
-
162
-
-
56349134317
-
Alpha-lipoic acid prevents mitochondrial damage and neurotoxicity in experimental chemotherapy neuropathy
-
G. Melli, M. Taiana, F. Camozzi, D. Triolo, P. Podini, A. Quattrini, F. Taroni, and G. Lauria Alpha-lipoic acid prevents mitochondrial damage and neurotoxicity in experimental chemotherapy neuropathy Exp. Neurol. 214 2008 276 284
-
(2008)
Exp. Neurol.
, vol.214
, pp. 276-284
-
-
Melli, G.1
Taiana, M.2
Camozzi, F.3
Triolo, D.4
Podini, P.5
Quattrini, A.6
Taroni, F.7
Lauria, G.8
-
163
-
-
0032755275
-
Morphological evidence of the inhibitory effect of taxol on the fast axonal transport
-
DOI 10.1016/S0168-0102(99)00074-7, PII S0168010299000747
-
T. Nakata, and H. Yorifuji Morphological evidence of the inhibitory effect of taxol on the fast axonal transport Neurosci. Res. 35 1999 113 122 (Pubitemid 29518402)
-
(1999)
Neuroscience Research
, vol.35
, Issue.2
, pp. 113-122
-
-
Nakata, T.1
Yorifuji, H.2
-
164
-
-
0033970658
-
Taxol impairs anterograde axonal transport of microinjected horseradish peroxidase in dorsal root ganglia neurons in vitro
-
DOI 10.1007/s004410050019
-
C. Theiss, and K. Meller Taxol impairs anterograde axonal transport of microinjected horseradish peroxidase in dorsal root ganglia neurons in vitro Cell Tissue Res. 299 2000 213 224 (Pubitemid 30103139)
-
(2000)
Cell and Tissue Research
, vol.299
, Issue.2
, pp. 213-224
-
-
Theiss, C.1
Meller, K.2
-
165
-
-
0033915199
-
Managing the neurotoxicity of paclitaxel (Taxol®) and docetaxel (Taxotere®) with neurotrophic factors
-
S.C. Apfel Managing the neurotoxicity of paclitaxel (Taxol) and docetaxel (Taxotere) with neurotrophic factors Cancer Investig. 18 2000 564 573 (Pubitemid 30485673)
-
(2000)
Cancer Investigation
, vol.18
, Issue.6
, pp. 564-573
-
-
Apfel, S.C.1
-
166
-
-
0036158822
-
Chemotherapy-induced peripheral neuropathy
-
S. Quasthoff, and H.P. Hartung Chemotherapy-induced peripheral neuropathy J. Neurol. 249 2002 9 17 (Pubitemid 34119018)
-
(2002)
Journal of Neurology
, vol.249
, Issue.1
, pp. 9-17
-
-
Quasthoff, S.1
Hartung, H.P.2
-
167
-
-
3142514196
-
Oxidative stress in neurodegeneration: Cause or consequence?
-
J.K. Andersen Oxidative stress in neurodegeneration: cause or consequence? Nat. Med. 10 Suppl 2004 S18 S25
-
(2004)
Nat. Med.
, vol.10
, Issue.SUPPL.
-
-
Andersen, J.K.1
-
168
-
-
70449678592
-
Olesoxime (cholest-4-en-3-one, oxime): Analgesic and neuroprotective effects in a rat model of painful peripheral neuropathy produced by the chemotherapeutic agent, paclitaxel
-
W.H. Xiao, F.Y. Zheng, G.J. Bennett, T. Bordet, and R.M. Pruss Olesoxime (cholest-4-en-3-one, oxime): analgesic and neuroprotective effects in a rat model of painful peripheral neuropathy produced by the chemotherapeutic agent, paclitaxel Pain 147 2009 202 209
-
(2009)
Pain
, vol.147
, pp. 202-209
-
-
Xiao, W.H.1
Zheng, F.Y.2
Bennett, G.J.3
Bordet, T.4
Pruss, R.M.5
-
169
-
-
0017894770
-
An association between mitochondria and microtubules in synaptosomes and axon terminals of cerebral cortex
-
DOI 10.1007/BF01217913
-
K.Y. Chan, and A.H. Bunt An association between mitochondria and microtubules in synaptosomes and axon terminals of cerebral cortex J. Neurocytol. 7 1978 137 143 (Pubitemid 8301219)
-
(1978)
Journal of Neurocytology
, vol.7
, Issue.2
, pp. 137-143
-
-
Chan, K.Y.1
Bunt, A.H.2
-
170
-
-
0019192282
-
2+: Evidence that microtubules are not required
-
DOI 10.1073/pnas.77.10.5909
-
S.T. Brady, S.D. Crothers, C. Nosal, and W.O. McClure Fast axonal transport in the presence of high Ca2+: evidence that microtubules are not required Proc. Natl Acad. Sci. USA 77 1980 5909 5913 (Pubitemid 11211230)
-
(1980)
Proceedings of the National Academy of Sciences of the United States of America
, vol.77
, Issue.II10
, pp. 5909-5913
-
-
Brady, S.T.1
Crothers, S.D.2
Nosal, C.3
McClure, W.O.4
-
171
-
-
0021136122
-
Gelsolin inhibition of fast axonal transport indicates a requirement of actin microfilaments
-
S.T. Brady, R.J. Lasek, R.D. Allen, H.L. Yin, and T.P. Stossel Gelsolin inhibition of fast axonal transport indicates a requirement for actin microfilaments Nature 310 1984 56 58 (Pubitemid 14077861)
-
(1984)
Nature
, vol.310
, Issue.5972
, pp. 56-58
-
-
Brady, S.T.1
Lasek, R.J.2
Allen, R.D.3
-
172
-
-
0020170121
-
Microinjection into an identified axon to study the mechanism of fast axonal transport
-
D.J. Goldberg Microinjection into an identified axon to study the mechanism of fast axonal transport Proc. Natl Acad. Sci. USA 79 1982 4818 4822
-
(1982)
Proc. Natl Acad. Sci. USA
, vol.79
, pp. 4818-4822
-
-
Goldberg, D.J.1
-
173
-
-
0019274004
-
Analysis of the mechanism of fast axonal transport by intracellular injection of potentially inhibitory macromolecules: Evidence for a possible role of actin filaments
-
DOI 10.1073/pnas.77.12.7448
-
D.J. Goldberg, D.A. Harris, B.W. Lubit, and J.H. Schwartz Analysis of the mechanism of fast axonal transport by intracellular injection of potentially inhibitory macromolecules: evidence for a possible role of actin filaments Proc. Natl Acad. Sci. USA 77 1980 7448 7452 (Pubitemid 11131147)
-
(1980)
Proceedings of the National Academy of Sciences of the United States of America
, vol.77
, Issue.II12
, pp. 7448-7452
-
-
Goldberg, D.J.1
Harris, D.A.2
Lubit, B.W.3
Schwartz, J.H.4
-
174
-
-
0028861992
-
Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons
-
R.L. Morris, and P.J. Hollenbeck Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons J. Cell Biol. 131 1995 1315 1326
-
(1995)
J. Cell Biol.
, vol.131
, pp. 1315-1326
-
-
Morris, R.L.1
Hollenbeck, P.J.2
-
175
-
-
77956594742
-
Microtubule dysfunction precedes transport impairment and mitochondria damage in MPP+-induced neurodegeneration
-
D. Cartelli, C. Ronchi, M.G. Maggioni, S. Rodighiero, E. Giavini, and G. Cappelletti Microtubule dysfunction precedes transport impairment and mitochondria damage in MPP+-induced neurodegeneration J. Neurochem. 115 2010 247 258
-
(2010)
J. Neurochem.
, vol.115
, pp. 247-258
-
-
Cartelli, D.1
Ronchi, C.2
Maggioni, M.G.3
Rodighiero, S.4
Giavini, E.5
Cappelletti, G.6
-
176
-
-
77950547934
-
The speed of mitochondrial movement is regulated by the cytoskeleton and myosin in Picea wilsonii pollen tubes
-
M. Zheng, Q. Wang, Y. Teng, X. Wang, F. Wang, T. Chen, J. Samaj, J. Lin, and D.C. Logan The speed of mitochondrial movement is regulated by the cytoskeleton and myosin in Picea wilsonii pollen tubes Planta 231 2010 779 791
-
(2010)
Planta
, vol.231
, pp. 779-791
-
-
Zheng, M.1
Wang, Q.2
Teng, Y.3
Wang, X.4
Wang, F.5
Chen, T.6
Samaj, J.7
Lin, J.8
Logan, D.C.9
-
177
-
-
34047175919
-
Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation
-
DOI 10.1523/JNEUROSCI.0037-07.2007
-
J.P. Dompierre, J.D. Godin, B.C. Charrin, F.P. Cordelieres, S.J. King, S. Humbert, and F. Saudou Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation J. Neurosci. 27 2007 3571 3583 (Pubitemid 46515140)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.13
, pp. 3571-3583
-
-
Dompierre, J.P.1
Godin, J.D.2
Charrin, B.C.3
Cordelieres, F.P.4
King, S.J.5
Humbert, S.6
Saudou, F.7
-
178
-
-
33750618516
-
Microtubule Acetylation Promotes Kinesin-1 Binding and Transport
-
DOI 10.1016/j.cub.2006.09.014, PII S096098220602207X
-
N.A. Reed, D. Cai, T.L. Blasius, G.T. Jih, E. Meyhofer, J. Gaertig, and K.J. Verhey Microtubule acetylation promotes kinesin-1 binding and transport Curr. Biol. 16 2006 2166 2172 (Pubitemid 44692098)
-
(2006)
Current Biology
, vol.16
, Issue.21
, pp. 2166-2172
-
-
Reed, N.A.1
Cai, D.2
Blasius, T.L.3
Jih, G.T.4
Meyhofer, E.5
Gaertig, J.6
Verhey, K.J.7
-
179
-
-
8844273265
-
Enhancement of paclitaxel-induced microtubule stabilization, mitotic arrest, and apoptosis by the microtubule-targeting agent EM012
-
DOI 10.1016/j.bcp.2004.08.032, PII S0006295204006380
-
J. Zhou, M. Liu, R. Aneja, R. Chandra, and H.C. Joshi Enhancement of paclitaxel-induced microtubule stabilization, mitotic arrest, and apoptosis by the microtubule-targeting agent EM012 Biochem. Pharmacol. 68 2004 2435 2441 (Pubitemid 39535116)
-
(2004)
Biochemical Pharmacology
, vol.68
, Issue.12
, pp. 2435-2441
-
-
Zhou, J.1
Liu, M.2
Aneja, R.3
Chandra, R.4
Joshi, H.C.5
-
180
-
-
37549047609
-
Evidence for microtubule target engagement in tumors of patients receiving ixabepilone
-
S.H. Zhuang, Y.E. Hung, L. Hung, R.W. Robey, D.L. Sackett, W.M. Linehan, S.E. Bates, T. Fojo, and M.S. Poruchynsky Evidence for microtubule target engagement in tumors of patients receiving ixabepilone Clin. Cancer Res. 13 2007 7480 7486
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 7480-7486
-
-
Zhuang, S.H.1
Hung, Y.E.2
Hung, L.3
Robey, R.W.4
Sackett, D.L.5
Linehan, W.M.6
Bates, S.E.7
Fojo, T.8
Poruchynsky, M.S.9
-
181
-
-
0023952233
-
Effects of intraneural injection of taxol on retrograde axonal transport and morphology of corresponding nerve cell bodies
-
I. Nennesmo, and F.P. Reinholt Effects of intraneural injection of taxol on retrograde axonal transport and morphology of corresponding nerve cell bodies Virchows Arch. B Cell Pathol. Incl. Mol. Pathol. 55 1988 241 246
-
(1988)
Virchows Arch. B Cell Pathol. Incl. Mol. Pathol.
, vol.55
, pp. 241-246
-
-
Nennesmo, I.1
Reinholt, F.P.2
-
182
-
-
76649143069
-
Posttranslational modifications of tubulin and the polarized transport of kinesin-1 in neurons
-
J.W. Hammond, C.F. Huang, S. Kaech, C. Jacobson, G. Banker, and K.J. Verhey Posttranslational modifications of tubulin and the polarized transport of kinesin-1 in neurons Mol. Biol. Cell 21 2010 572 583
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 572-583
-
-
Hammond, J.W.1
Huang, C.F.2
Kaech, S.3
Jacobson, C.4
Banker, G.5
Verhey, K.J.6
-
183
-
-
0032799381
-
Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles
-
B. Trinczek, A. Ebneth, E.M. Mandelkow, and E. Mandelkow Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles J. Cell Sci. 112 Pt 14 1999 2355 2367 (Pubitemid 29381026)
-
(1999)
Journal of Cell Science
, vol.112
, Issue.14
, pp. 2355-2367
-
-
Trinczek, B.1
Ebneth, A.2
Mandelkow, E.-M.3
Mandelkow, E.4
-
184
-
-
0031469160
-
Overexpression of MAP4 inhibits organelle motility and trafficking in vivo
-
J.C. Bulinski, T.E. McGraw, D. Gruber, H.L. Nguyen, and M.P. Sheetz Overexpression of MAP4 inhibits organelle motility and trafficking in vivo J. Cell Sci. 110 Pt 24 1997 3055 3064
-
(1997)
J. Cell Sci.
, vol.110
, Issue.PART 24
, pp. 3055-3064
-
-
Bulinski, J.C.1
McGraw, T.E.2
Gruber, D.3
Nguyen, H.L.4
Sheetz, M.P.5
-
185
-
-
0037119947
-
Single-molecule investigation of the interference between kinesin, tau and MAP2c
-
A. Seitz, H. Kojima, K. Oiwa, E.M. Mandelkow, Y.H. Song, and E. Mandelkow Single-molecule investigation of the interference between kinesin, tau and MAP2c EMBO J. 21 2002 4896 4905
-
(2002)
EMBO J.
, vol.21
, pp. 4896-4905
-
-
Seitz, A.1
Kojima, H.2
Oiwa, K.3
Mandelkow, E.M.4
Song, Y.H.5
Mandelkow, E.6
-
186
-
-
0028793720
-
Enhanced interaction between tubulin and microtubule-associated protein 2 via inhibition of MAP kinase and CDC2 kinase by paclitaxel
-
K. Nishio, H. Arioka, T. Ishida, H. Fukumoto, H. Kurokawa, M. Sata, M. Ohata, and N. Saijo Enhanced interaction between tubulin and microtubule-associated protein 2 via inhibition of MAP kinase and CDC2 kinase by paclitaxel Int. J. Cancer 63 1995 688 693
-
(1995)
Int. J. Cancer
, vol.63
, pp. 688-693
-
-
Nishio, K.1
Arioka, H.2
Ishida, T.3
Fukumoto, H.4
Kurokawa, H.5
Sata, M.6
Ohata, M.7
Saijo, N.8
-
187
-
-
33644551565
-
A motor neuron disease-associated mutation in p150Glued perturbs dynactin function and induces protein aggregation
-
J.R. Levy, C.J. Sumner, J.P. Caviston, M.K. Tokito, S. Ranganathan, L.A. Ligon, K.E. Wallace, B.H. LaMonte, G.G. Harmison, I. Puls, K.H. Fischbeck, and E.L. Holzbaur A motor neuron disease-associated mutation in p150Glued perturbs dynactin function and induces protein aggregation J. Cell Biol. 172 2006 733 745
-
(2006)
J. Cell Biol.
, vol.172
, pp. 733-745
-
-
Levy, J.R.1
Sumner, C.J.2
Caviston, J.P.3
Tokito, M.K.4
Ranganathan, S.5
Ligon, L.A.6
Wallace, K.E.7
Lamonte, B.H.8
Harmison, G.G.9
Puls, I.10
Fischbeck, K.H.11
Holzbaur, E.L.12
-
188
-
-
58149214025
-
Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity
-
J. Jaworski, L.C. Kapitein, S.M. Gouveia, B.R. Dortland, P.S. Wulf, I. Grigoriev, P. Camera, S.A. Spangler, P. Di Stefano, J. Demmers, H. Krugers, P. Defilippi, A. Akhmanova, and C.C. Hoogenraad Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity Neuron 61 2009 85 100
-
(2009)
Neuron
, vol.61
, pp. 85-100
-
-
Jaworski, J.1
Kapitein, L.C.2
Gouveia, S.M.3
Dortland, B.R.4
Wulf, P.S.5
Grigoriev, I.6
Camera, P.7
Spangler, S.A.8
Di Stefano, P.9
Demmers, J.10
Krugers, H.11
Defilippi, P.12
Akhmanova, A.13
Hoogenraad, C.C.14
-
189
-
-
77449107515
-
Paclitaxel induces axonal microtubules polar reconfiguration and impaired organelle transport: Implications for the pathogenesis of paclitaxel-induced polyneuropathy
-
O.A. Shemesh, and M.E. Spira Paclitaxel induces axonal microtubules polar reconfiguration and impaired organelle transport: implications for the pathogenesis of paclitaxel-induced polyneuropathy Acta Neuropathol. 119 2010 235 248
-
(2010)
Acta Neuropathol.
, vol.119
, pp. 235-248
-
-
Shemesh, O.A.1
Spira, M.E.2
-
190
-
-
45749117188
-
Mitochondrial fragmentation in neurodegeneration
-
DOI 10.1038/nrn2417, PII NRN2417
-
A.B. Knott, G. Perkins, R. Schwarzenbacher, and E. Bossy-Wetzel Mitochondrial fragmentation in neurodegeneration Nat. Rev. Neurosci. 9 2008 505 518 (Pubitemid 351873464)
-
(2008)
Nature Reviews Neuroscience
, vol.9
, Issue.7
, pp. 505-518
-
-
Knott, A.B.1
Perkins, G.2
Schwarzenbacher, R.3
Bossy-Wetzel, E.4
-
191
-
-
57649210194
-
Impairing the mitochondrial fission and fusion balance: A new mechanism of neurodegeneration
-
A.B. Knott, and E. Bossy-Wetzel Impairing the mitochondrial fission and fusion balance: a new mechanism of neurodegeneration Ann. NY Acad. Sci. 1147 2008 283 292
-
(2008)
Ann. NY Acad. Sci.
, vol.1147
, pp. 283-292
-
-
Knott, A.B.1
Bossy-Wetzel, E.2
-
192
-
-
58349112352
-
Mitochondrial remodeling in differentiating neuroblasts
-
V. Voccoli, and L. Colombaioni Mitochondrial remodeling in differentiating neuroblasts Brain Res. 1252 2009 15 29
-
(2009)
Brain Res.
, vol.1252
, pp. 15-29
-
-
Voccoli, V.1
Colombaioni, L.2
-
193
-
-
62149125579
-
A novel method for analyzing mitochondrial movement: Inhibition by paclitaxel in a pheochromocytoma cell model
-
T. Shprung, and I. Gozes A novel method for analyzing mitochondrial movement: inhibition by paclitaxel in a pheochromocytoma cell model J. Mol. Neurosci. 37 2009 254 262
-
(2009)
J. Mol. Neurosci.
, vol.37
, pp. 254-262
-
-
Shprung, T.1
Gozes, I.2
-
194
-
-
49349112331
-
Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization
-
R. Yamaguchi, L. Lartigue, G. Perkins, R.T. Scott, A. Dixit, Y. Kushnareva, T. Kuwana, M.H. Ellisman, and D.D. Newmeyer Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization Mol. Cell 31 2008 557 569
-
(2008)
Mol. Cell
, vol.31
, pp. 557-569
-
-
Yamaguchi, R.1
Lartigue, L.2
Perkins, G.3
Scott, R.T.4
Dixit, A.5
Kushnareva, Y.6
Kuwana, T.7
Ellisman, M.H.8
Newmeyer, D.D.9
-
195
-
-
0035578214
-
Accompanying protein alterations in malignant cells with a microtubule-polymerizing drug-resistance phenotype and a primary resistance mechanism
-
DOI 10.1016/S0006-2952(01)00804-8, PII S0006295201008048
-
M.S. Poruchynsky, P. Giannakakou, Y. Ward, J.C. Bulinski, W.G. Telford, R.W. Robey, and T. Fojo Accompanying protein alterations in malignant cells with a microtubule-polymerizing drug-resistance phenotype and a primary resistance mechanism Biochem. Pharmacol. 62 2001 1469 1480 (Pubitemid 33145290)
-
(2001)
Biochemical Pharmacology
, vol.62
, Issue.11
, pp. 1469-1480
-
-
Poruchynsky, M.S.1
Giannakakou, P.2
Ward, Y.3
Chloe Bulinski, J.4
Telford, W.G.5
Robey, R.W.6
Fojo, T.7
|