Olesoxime prevents microtubule-targeting drug neurotoxicity: Selective preservation of EB comets in differentiated neuronal cells

Biochemical Pharmacology

Volumn 80, Issue 6, 2010, Pages 884-894

  Rovini, Amandine ^a   Carré, Manon ^a   Bordet, Thierry ^b   Pruss, Rebecca M ^b   Braguer, Diane ^a  

^a University of the Mediterranean Aix Marseille II   (France)

^b Trophos   (France)

Author keywords

EB proteins; Microtubule; Mitochondria; Neuroprotection; Taxanes; Vinca alkaloids

Indexed keywords

END BINDING 1 PROTEIN; END BINDING 3 PROTEIN; NEUROPROTECTIVE AGENT; OLESOXIME; PROTEIN; TRO 19622; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENUATION; BRAIN ATROPHY; BRAIN NERVE CELL; CANCER CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRAIN; CYTOTOXICITY; CYTOTOXICITY TEST; DRUG MECHANISM; ENDOTHELIUM CELL; GLIOBLASTOMA; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MICROTUBULE; NEUROBLASTOMA CELL; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; TUMOR CELL; WESTERN BLOTTING;

ANIMALS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CHOLESTENONES; COMET ASSAY; DRUG DELIVERY SYSTEMS; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; NEURONS; NEUROPROTECTIVE AGENTS; PC12 CELLS; RATS; VINCA ALKALOIDS;

EID: 77954762893     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.04.018     Document Type: Article

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