Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate

EMBO Journal

Volumn 20, Issue 22, 2001, Pages 6306-6315

  Makin, Guy W J ^a   Corfe, Bernard M ^a   Griffiths, Gareth J ^a   Thistlethwaite, Angela ^a   Hickman, John A ^b   Dive, Caroline ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

Bax; Chemoresistance; Mitochondria; Neuroblastoma; Taxol

Indexed keywords

CISPLATIN; CYTOCHROME C; CYTOTOXIN; EPITOPE; PACLITAXEL; PROTEIN BAX;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; CANCER RESISTANCE; CELL FATE; CELL SURVIVAL; COMPLEX FORMATION; CONTROLLED STUDY; DIMERIZATION; DNA FLANKING REGION; GENE ACTIVATION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; MITOCHONDRION; NEUROBLASTOMA CELL; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CASPASES; CELL LINEAGE; CELL SURVIVAL; CISPLATIN; CYTOCHROME C GROUP; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; EPITOPES; FLOW CYTOMETRY; HUMANS; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; NEUROBLASTOMA; PACLITAXEL; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SUBCELLULAR FRACTIONS; TIME FACTORS; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0035890335     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.22.6306     Document Type: Article

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