Unique induction of p21WAF1/CIP1 expression by vinorelbine in androgen-independent prostate cancer cells

British Journal of Cancer

Volumn 89, Issue 8, 2003, Pages 1566-1573

  Liu, X M ^a   Jiang, J D ^a   Ferrari, A C ^a   Budman, D R ^b   Wang, L G ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b NORTH SHORE UNIVERSITY HOSPITAL   (United States)

Author keywords

Androgen independent cell; p21 WAF1 CIP1induction; p21WAF1 CIP1 deficit cell; Vinorelbine and paclitaxel

Indexed keywords

ANDROGEN; LUCIFERASE; NAVELBINE; PACLITAXEL; PROTEIN P21; PROTEIN P53;

ADVANCED CANCER; APOPTOSIS; ARTICLE; BINDING SITE; CANCER CELL CULTURE; CELL CYCLE; CONTROLLED STUDY; DNA TRANSFECTION; DRUG POTENTIATION; GENE DELETION; GENE EXPRESSION; HORMONE DEPENDENCE; HUMAN; HUMAN CELL; IC 50; PRIORITY JOURNAL; PROSTATE CANCER; REPORTER GENE; WESTERN BLOTTING;

ANDROGEN ANTAGONISTS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DRUG INTERACTIONS; DRUG RESISTANCE, NEOPLASM; DRUG THERAPY, COMBINATION; ENZYME INHIBITORS; GENE DELETION; GENE EXPRESSION REGULATION, NEOPLASTIC; MALE; PACLITAXEL; PROSTATIC NEOPLASMS; TUMOR CELLS, CULTURED; VINBLASTINE;

EID: 0242407074     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6601317     Document Type: Article

References (36)

1. Ali S, Aranha O, Li Y, Pettit GR, Sarkar FH, Philip PA (2003) Sensitization of human breast cancer cells to gemcitabine by the protein kinase C modulator bryostatin 1. Cancer Chemother Pharmacol 52(3): 235-246
2. Barboule N, Chadebech P, Baldin V, Vidai S, Valette A (1997) Involvement of p21 in mitotic exit after paclitaxel treatment in MCF-7 breast adenocarcinoma cell line. Oncogene 15: 2867-2875
3. Biggs JR, Kudlow JE, Kraft AS (1996) The role of the transcription factor Spl in regulating the expression of the WAF1/CIP1 gene in U937 leukemic cells. J Biol Chem 271: 901-906
4. Billon N, Carlisi D, Datto MB, van Grunsven LA, Watt A, Wang XF, Rudkin BB (1999) Cooperation of Spl and p300 in the induction of the CDK inhibitor p21WAF1/CIP1 during NGF-mediated neuronal differentiation. Oncogene 18: 2872-2882
5. Blagosklonny MV, Schulte TW, Nguyen P, Mimnaugh EG, Trepel J, Neckers L (1995) Taxol induction of p21WAF1 and p53 requires c-raf-1. Cancer Res 55: 4623-4626
6. Budman DR (1997) Vinorelbine (Navelbine): a third-generation vinca alkaloid. Cancer Invest 15: 475-490
7. Budman DR, Calabro A, Wang LG, Liu XM, Stiel L, Adams LM, Kreis W (2000) Synergism of cytotoxic effects of vinorelbine and paclitaxel in vitro. Cancer Invest 18: 695-701
8. Charles AG, Han TY, Liu YY, Hansen N, Giuliano AE, Cabot MC (2001) Taxol-induced ceramide generation and apoptosis in human breast cancer cells. Cancer Chemother Pharmacol 47: 444-450
9. Datto MB, Yu Y, Wang XF (1995) Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter. J Biol Chem 270: 28623-28628
10. Fan M, Goodwin ME, Birrer MJ, Chambers TC (2001) The c-Jun NH(2) -terminal protein kinase/AP-1 pathway is required for efficient apoptosis induced by vinblastine. Cancer Res 61: 4450-4458
11. Ganansia-Leymarie V, Bischoff P, Bergerat JP, Roll V (2003) Signal transduction pathways of taxanes-induced apoptosis. Curr Med Chem Anti-Cancer Agents 3: 291-306
12. Gao M, Ossowski L, Ferrari AC (1999) Activation of Rb and decline in androgen receptor protein precede retinoic acid-induced apoptosis in androgen-dependent LNCaP cells and their androgen-independent derivative. J Cell Physiol 179: 336-346
13. Gartel AL, Tyner AL (1999) Transcriptional regulation of the p21((WAF1/ CIP1)) gene. Exp Cell Res 246: 280-289
14. Hochhauser D, Schnieders B, Ercikan-Abali E, Gorlick R, Muise-Helmericks R, Li WW, Fan J, Banerjee D, Bertino JR (1996) Effect of cyclin D1 overexpression on drug sensitivity in a human fibrosarcoma cell line. J Natl Cancer Inst 88: 1269-1275
15. Huggins C, Hodges CV (1941) Studies on prostatic cancer: I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. Cancer Res 1: 293-297
16. Kreis W, Budman DR, Calabro A (1997) Unique synergism or antagonism of combinations of chemotherapeutic and hormonal agents in human prostate cancer cell lines. Br J Urol 79: 196-202
17. Krikorian A, Breillout F (1991) Vinorelbine (Navelbine). A new semisynthetic vinca alkaloid. Onkologie 14: 7-12
18. Lee SJ, Ha MJ, Lee J, Nguyen P, Choi YH, Pirnia F, Kang WK, Wang XF, Kim SJ, Trepel JB (1998) Inhibition of the 3-hydroxy-3-methylglutarylcoenzyme A reductase pathway induces p53-independent transcriptional regulation of p21(WAF1/CIP1) in human prostate carcinoma cells. J Biol Chem 273: 10618-10623
19. Lee WS, Chen RJ, Wang YJ, Tseng H, Jeng JH, Lin SY, Liang YC, Chen CH, Lin CH, Lin JK, Ho PY, Chu JS, Ho WL, Chen LC, Ho YS (2003) In vitro and in vivo studies of the anticancer action of terbinafine in human cancer cell lines: GO/G1 p53-associated cell cycle arrest. Int J Cancer 106: 125-137
20. Li WW, Fan J, Hochhauser D, Bertino JR (1997) Overexpression of p21waf1 leads to increased inhibition of E2F-1 phosphorylation and sensitivity to anticancer drugs in retinoblastoma-negative human sarcoma cells. Cancer Res 57: 2193-2199
21. Lilenbaum R (2001) Options in advanced non-small cell lung cancer: a review and report on a phase II study of vinorelbine plus gemcitabine. Oncologist 6(Suppl 1): 16-19
22. Linke SP, Clarkin KC, Di Leonardo A, Tsou A, Wahl GM (1996) A reversible, p53-dependent GO/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage. Genes Dev 10: 934-947
23. Liu XM, Wang LG, Kreis W, Budman DR, Adams LM (2001) Differential effect of vinorelbine versus paclitaxel on ERK2 kinase activity during apoptosis in MCF-7 cells. Br J Cancer 85: 1403-1411
24. Lu S, Jenster G, Epner DE (2000) Androgen induction of cyclin-dependent kinase inhibitor p21 gene: role of androgen receptor and transcription factor Spl complex. Mol Endocrinol 14: 753-760
25. Nakano K, Mizuno T, Sowa Y, Orita T, Yoshino T, Okuyama Y, Fujita T, Ohtani-Fujita N, Matsukawa Y, Tokino T, Yamagishi H, Oka T, Nomura H, Sakai T (1997) Butyrate activates the WAF1/Cip1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line. J Biol Chem 272: 22199-22206
26. Prowse DM, Bolgan L, Molnar A, Dotto GP (1997) Involvement of the Sp3 transcription factor in induction of p21Cip1/WAF1 in keratinocyte differentiation. J. BM. Chem. 272: 1308-1314
27. Schwartz GK, O'Reilly E, Ilson D, Saltz L, Sharma S, Tong W, Maslak P, Stoltz M, Eden L, Perkins P, Endres S, Barazzoul J, Spriggs D, Kelsen D (2002) Phase I study of the cyclin-dependent kinase inhibitor flavopiridol in combination with paclitaxel in patients with advanced solid tumors. J Clin Oncol 20: 2157-2170
28. Sowa Y, Orita T, Minamikawa S, Nakano K, Mizuno T, Nomura H, Sakai T (1997) Histone deacetylase inhibitor activates the WAF1/Cip1 gene promoter through the Sp1 sites. Biochem Biophys Res Commun 241: 142-150
29. St Croix B, Florenes VA, Rak JW, Flanagan M, Bhattacharya N, Slingerland JM, Kerbel RS (1996) Impact of the cyclin-dependent kinase inhibitor p27Kip1 on resistance of tumor cells to anticancer agents. Nat Med 2: 1204-1210
30. Torres K, Horwitz SB (1998) Mechanisms of Taxol-induced cell death are concentration dependent. Cancer Res 58: 3620-3626
31. Trimble EL (2000) Innovative therapies for advanced ovarian cancer. Semin Oncol 27: 24-30
32. Wang LG, Liu XM, Budman DR, Kreis W (1999a) Synergistic effect of estramustine and [3′-keto-Bmtl]-[Val2]-cyclosporine (PSC 833) on the inhibition of androgen receptor phosphorylation in LNCaP cells. Biochem Pharmacol 58: 1115-1121
33. Wang LG, Liu XM, Kreis W, Budman DR (1997) Down-regulation of prostate-specific antigen expression by finasteride through inhibition of complex formation between androgen receptor and steroid receptor-binding consensus in the promoter of the PSA gene in LNCaP cells. Cancer Res 57: 714-719
34. Wang LG, Liu XM, Kreis W, Budman DR (1999b) The effect of antimicrotubule agents on signal transduction pathways of apoptosis: a review. Cancer Chemother Pharmacol 44: 355-361
35. Wang LG, Ossowski L, Ferrari AC (2001) Overexpressed androgen receptor linked to p21(WAF1) silencing may be responsible for androgen independence and resistance to apoptosis of a prostate cancer cell line. Cancer Res 61: 7544-7551
36. Wang TH, Wang HS, Soong YK (2000) Paclitaxel-induced cell death: where the cell cycle and apoptosis come together. Cancer 88: 2619-2628