HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim

EMBO Journal

Volumn 21, Issue 24, 2002, Pages 6801-6810

  Chen, Dan ^a   Wang, Michael ^b   Zhou, Sharleen ^a   Zhou, Qiang ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

Author keywords

Apoptosis; Bim; HIV 1; Microtubule; Tat

Indexed keywords

BIM PROTEIN; PROTEIN BCL 2; TRANSACTIVATOR PROTEIN; TUBULIN; UNCLASSIFIED DRUG;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING AFFINITY; BYSTANDER EFFECT; CYTOSKELETON; HOST CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE DEPLETION; MICROTUBULE; MITOCHONDRION; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PURIFICATION; PROTEIN SECRETION; PROTEIN TARGETING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CARRIER PROTEINS; CD4-POSITIVE T-LYMPHOCYTES; CELL DEATH; CELL LINE; CYTOPLASM; CYTOSKELETON; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; FLOW CYTOMETRY; G1 PHASE; GENE PRODUCTS, TAT; GLUTATHIONE TRANSFERASE; HIV-1; HUMANS; JURKAT CELLS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; MICROTUBULES; MITOCHONDRIA; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RETROVIRIDAE; TRANSFECTION; TUBULIN;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 12244304872     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdf683     Document Type: Article

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