Cutting edge: Depletion of Foxp3+ cells leads to induction of autoimmunity by specific ablation of regulatory T cells in genetically targeted mice

Journal of Immunology

Volumn 183, Issue 12, 2009, Pages 7631-7634

  Kim, Jeong ^a,g   Lahl, Katharina ^b   Hori, Shohei ^c   Loddenkemper, Christoph ^d   Chaudhry, Ashutosh ^a   DeRoos, Paul ^a,h   Rudensky, Alexander ^a   Sparwasser, Tim ^e,f  

^a UNIVERSITY OF WASHINGTON   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c RIKEN Center for Integrative Medical Sciences   (Japan)

^d Research Center ImmunoSciences   (Germany)

^e INSTITUTE OF INFECTION IMMUNOLOGY   (Germany)

^f HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^g GENENTECH INC   (United States)

^h MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIPHTHERIA TOXIN; TRANSCRIPTION FACTOR FOXP3; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CELL ASSAY; CONTROLLED STUDY; GENE EXPRESSION; GENETICS; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; REGULATORY T LYMPHOCYTE; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; C57BL MOUSE; EPITHELIUM CELL; GENE TARGETING; IMMUNOLOGY; LUNG; LYMPHOCYTE DEPLETION; MALE; METABOLISM; MOUSE MUTANT; PATHOLOGY; PROSTATE; THYMUS; TRANSGENIC MOUSE;

ANIMALS; AUTOIMMUNE DISEASES; EPITHELIAL CELLS; FORKHEAD TRANSCRIPTION FACTORS; GENE TARGETING; LUNG; LYMPHOCYTE DEPLETION; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PROSTATE; T-LYMPHOCYTES, REGULATORY; THYMUS GLAND;

EID: 76249088097     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0804308     Document Type: Article

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