Inhaled innate immune ligands to prevent pneumonia

British Journal of Pharmacology

Volumn 163, Issue 1, 2011, Pages 195-206

  Evans, Scott E ^a   Tuvim, Michael J ^a   Fox, Cory J ^a   Sachdev, Nidhi ^a   Gibiansky, Leonid ^b   Dickey, Burton F ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b QuantPharm LLC 49 Flints Grove Drive   (United States)

Author keywords

aerosol; antimicrobial peptides; epithelium; infection; innate immunity; lung; pneumonia; resistance; TLR; Toll like receptor

Indexed keywords

ANTIINFECTIVE AGENT; CASPASE; CPG OLIGODEOXYNUCLEOTIDE; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 33; LIPOPOLYSACCHARIDE; MACROPHAGE ACTIVATING LIPOPEPTIDE 2; OLIGODEOXYNUCLEOTIDE; PAM 2; PROTEIN MD 2; RETINOIC ACID; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR AGONIST; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ANTIBIOTIC RESISTANCE; ARTIFICIAL VENTILATION; CANCER PATIENT; CELL PROLIFERATION; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG FORMULATION; DRUG POTENTIATION; ENZYME METABOLISM; GENE EXPRESSION; HIGH RISK POPULATION; HUMAN; IN VIVO STUDY; INNATE IMMUNITY; INTRACELLULAR SIGNALING; LOWER RESPIRATORY TRACT INFECTION; LUNG INFECTION; LUNG LAVAGE; METAPLASIA; NONHUMAN; OLIGOMERIZATION; OVERALL SURVIVAL; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SEASONAL INFLUENZA; VIRAL RESPIRATORY TRACT INFECTION; VIRULENCE;

ADMINISTRATION, INHALATION; ANIMALS; EPITHELIAL CELLS; HUMANS; IMMUNITY, INNATE; LIGANDS; LUNG; PNEUMONIA;

EID: 79953721171     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01237.x     Document Type: Review

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