-
1
-
-
2942720573
-
The nature of small-airway obstruction in chronic obstructive pulmonary disease
-
Hogg JC, Chu F, Utokaparch S, Woods R, Elliott WM, Buzatu L, Cherniack RM, Rogers RM, Sciurba FC, Coxson HO, et al. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 2004;350:2645-2653.
-
(2004)
N Engl J Med
, vol.350
, pp. 2645-2653
-
-
Hogg, J.C.1
Chu, F.2
Utokaparch, S.3
Woods, R.4
Elliott, W.M.5
Buzatu, L.6
Cherniack, R.M.7
Rogers, R.M.8
Sciurba, F.C.9
Coxson, H.O.10
-
2
-
-
0141928029
-
Chronic obstructive pulmonary disease: Molecular and cellular mechanisms
-
Barnes PJ, Shapiro SD, Pauwels RA. Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur Respir J 2003;22:672-688.
-
(2003)
Eur Respir J
, vol.22
, pp. 672-688
-
-
Barnes, P.J.1
Shapiro, S.D.2
Pauwels, R.A.3
-
3
-
-
0037304945
-
Acquired somatic mutations in the molecular pathogenesis of COPD
-
Anderson GP, Bozinovski S. Acquired somatic mutations in the molecular pathogenesis of COPD. Trends Pharmacol Sci 2003;24:71-76.
-
(2003)
Trends Pharmacol Sci
, vol.24
, pp. 71-76
-
-
Anderson, G.P.1
Bozinovski, S.2
-
4
-
-
0035218753
-
Chronic obstructive pulmonary disease: An overview of pathology and pathogenesis
-
Hogg JC. Chronic obstructive pulmonary disease: an overview of pathology and pathogenesis. Novartis Found Symp 2001;234:4-19.
-
(2001)
Novartis Found Symp
, vol.234
, pp. 4-19
-
-
Hogg, J.C.1
-
5
-
-
4344675455
-
Pathophysiology of airflow limitation in chronic obstructive pulmonary disease
-
Hogg JC. Pathophysiology of airflow limitation in chronic obstructive pulmonary disease. Lancet 2004;364:709-721.
-
(2004)
Lancet
, vol.364
, pp. 709-721
-
-
Hogg, J.C.1
-
6
-
-
2942735127
-
Small airways in COPD
-
Barnes PJ. Small airways in COPD. N Engl J Med 2004;350:2635-2637.
-
(2004)
N Engl J Med
, vol.350
, pp. 2635-2637
-
-
Barnes, P.J.1
-
7
-
-
0012626868
-
New concepts in chronic obstructive pulmonary disease
-
Barnes PJ. New concepts in chronic obstructive pulmonary disease. Annu Rev Med 2003;54:113-129.
-
(2003)
Annu Rev Med
, vol.54
, pp. 113-129
-
-
Barnes, P.J.1
-
8
-
-
0034032761
-
Comparison of the structural and inflammatory features of COPD and asthma. Giles F. Filley Lecture
-
Jeffery PK. Comparison of the structural and inflammatory features of COPD and asthma. Giles F. Filley Lecture. Chest 2000;117:251S-260S.
-
(2000)
Chest
, vol.117
-
-
Jeffery, P.K.1
-
9
-
-
0032014542
-
CD81 T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease
-
Saetta M, Di Stefano A, Turato G, Facchini FM, Corbino L, Mapp CE, Maestrelli P, Ciaccia A, Fabbri LM. CD81 T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998;157:822-826.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 822-826
-
-
Saetta, M.1
Di Stefano, A.2
Turato, G.3
Facchini, F.M.4
Corbino, L.5
Mapp, C.E.6
Maestrelli, P.7
Ciaccia, A.8
Fabbri, L.M.9
-
10
-
-
0032698544
-
The macrophage in chronic obstructive pulmonary disease
-
Shapiro SD. The macrophage in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999;160:S29-S32.
-
(1999)
Am J Respir Crit Care Med
, vol.160
-
-
Shapiro, S.D.1
-
11
-
-
0035219462
-
Lymphocytes, chronic bronchitis and chronic obstructive pulmonary disease
-
Jeffery PK. Lymphocytes, chronic bronchitis and chronic obstructive pulmonary disease. Novartis Found Symp 2001;234:149-161.
-
(2001)
Novartis Found Symp
, vol.234
, pp. 149-161
-
-
Jeffery, P.K.1
-
12
-
-
0034721232
-
Chronic obstructive pulmonary disease
-
Barnes PJ. Chronic obstructive pulmonary disease. N Engl J Med 2000;343:269-280.
-
(2000)
N Engl J Med
, vol.343
, pp. 269-280
-
-
Barnes, P.J.1
-
13
-
-
0035744614
-
Cytokines in chronic obstructive pulmonary disease
-
Chung KF. Cytokines in chronic obstructive pulmonary disease. Eur Respir J Suppl 2001;34:50s-59s.
-
(2001)
Eur Respir J Suppl
, vol.34
-
-
Chung, K.F.1
-
14
-
-
0031954369
-
Structural and inflammatory changes in COPD: A comparison with asthma
-
Jeffery PK. Structural and inflammatory changes in COPD: a comparison with asthma. Thorax 1998;53:129-136.
-
(1998)
Thorax
, vol.53
, pp. 129-136
-
-
Jeffery, P.K.1
-
15
-
-
0035423344
-
End-stage chronic obstructive pulmonary disease: The cigarette is burned out but inflammation rages on
-
Shapiro SD. End-stage chronic obstructive pulmonary disease: the cigarette is burned out but inflammation rages on. Am J Respir Crit Care Med 2001;164:339-340.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 339-340
-
-
Shapiro, S.D.1
-
16
-
-
15744364004
-
Characterization of T lymphocytes in chronic obstructive pulmonary disease
-
Barnes PJ, Cosio MG. Characterization of T lymphocytes in chronic obstructive pulmonary disease. PLoS Med 2004;1:e20.
-
(2004)
PLoS Med
, vol.1
-
-
Barnes, P.J.1
Cosio, M.G.2
-
17
-
-
15744363493
-
An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema
-
Grumelli S, Corry DB, Song LZ, Song L, Green L, Huh J, Hacken J, Espada R, Bag R, Lewis DE, et al. An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema. PLoS Med 2004;1:e8.
-
(2004)
PLoS Med
, vol.1
-
-
Grumelli, S.1
Corry, D.B.2
Song, L.Z.3
Song, L.4
Green, L.5
Huh, J.6
Hacken, J.7
Espada, R.8
Bag, R.9
Lewis, D.E.10
-
18
-
-
0035662726
-
Nontypeable Haemophilus influenzae in the lower respiratory tract of patients with chronic bronchitis
-
Bandi V, Apicella MA, Mason E, Murphy TF, Siddiqi A, Atmar RL, Greenberg SB. Nontypeable Haemophilus influenzae in the lower respiratory tract of patients with chronic bronchitis. Am J Respir Crit Care Med 2001;164:2114-2119.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 2114-2119
-
-
Bandi, V.1
Apicella, M.A.2
Mason, E.3
Murphy, T.F.4
Siddiqi, A.5
Atmar, R.L.6
Greenberg, S.B.7
-
19
-
-
0032717535
-
Airway inflammation and bronchial microbial patterns in patients with stable chronic obstructive pulmonary disease
-
Soler N, Ewig S, Torres A, Filella X, Gonzalez J, Zaubet A. Airway inflammation and bronchial microbial patterns in patients with stable chronic obstructive pulmonary disease. Eur Respir J 1999;14:1015-1022.
-
(1999)
Eur Respir J
, vol.14
, pp. 1015-1022
-
-
Soler, N.1
Ewig, S.2
Torres, A.3
Filella, X.4
Gonzalez, J.5
Zaubet, A.6
-
20
-
-
0029085092
-
Bacterial infection in chronic obstructive pulmonary disease: A study of stable and exacerbated outpatients using the protected specimen brush
-
Monso E, Ruiz J, Rosell A, Manterola J, Fiz J, Morera J, Ausina V. Bacterial infection in chronic obstructive pulmonary disease: a study of stable and exacerbated outpatients using the protected specimen brush. Am J Respir Crit Care Med 1995;152:1316-1320.
-
(1995)
Am J Respir Crit Care Med
, vol.152
, pp. 1316-1320
-
-
Monso, E.1
Ruiz, J.2
Rosell, A.3
Manterola, J.4
Fiz, J.5
Morera, J.6
Ausina, V.7
-
21
-
-
0033018960
-
Predisposing factors to bacterial colonization in chronic obstructive pulmonary disease
-
Zalacain R, Sobradillo V, Amilibia J, Barron J, Achotegui V, Pijoan JI, Llorente JL. Predisposing factors to bacterial colonization in chronic obstructive pulmonary disease. Eur Respir J 1999;13:343-348.
-
(1999)
Eur Respir J
, vol.13
, pp. 343-348
-
-
Zalacain, R.1
Sobradillo, V.2
Amilibia, J.3
Barron, J.4
Achotegui, V.5
Pijoan, J.I.6
Llorente, J.L.7
-
22
-
-
0033764787
-
Evidence of bacterial infection in acute exacerbations of chronic bronchitis
-
Wilson R. Evidence of bacterial infection in acute exacerbations of chronic bronchitis. Semin Respir Infect 2000;15:208-215.
-
(2000)
Semin Respir Infect
, vol.15
, pp. 208-215
-
-
Wilson, R.1
-
23
-
-
0034100579
-
Haemophilus influenzae in chronic bronchitis
-
Murphy TF. Haemophilus influenzae in chronic bronchitis. Semin Respir Infect 2000;15:41-51.
-
(2000)
Semin Respir Infect
, vol.15
, pp. 41-51
-
-
Murphy, T.F.1
-
24
-
-
0033943481
-
Characterization of adherence of non-typeable Haemophilus influenzae to human epithelial cells
-
van Schilfgaarde M, van Ulsen P, Eijk P, Brand M, Stam M, Kouame J, van Alphen L, Dankert J. Characterization of adherence of non-typeable Haemophilus influenzae to human epithelial cells. Infect Immun 2000;68:4658-4665.
-
(2000)
Infect Immun
, vol.68
, pp. 4658-4665
-
-
van Schilfgaarde, M.1
van Ulsen, P.2
Eijk, P.3
Brand, M.4
Stam, M.5
Kouame, J.6
van Alphen, L.7
Dankert, J.8
-
25
-
-
0033135754
-
Haemophilus influenzae localized in epithelial cell layers is shielded from antibiotics and antibody-mediated bactericidal activity
-
van Schilfgaarde M, Eijk P, Regelink A, van Ulsen P, Everts V, Dankert J, van Alphen L. Haemophilus influenzae localized in epithelial cell layers is shielded from antibiotics and antibody-mediated bactericidal activity. Microb Pathog 1999;26:249-262.
-
(1999)
Microb Pathog
, vol.26
, pp. 249-262
-
-
van Schilfgaarde, M.1
Eijk, P.2
Regelink, A.3
van Ulsen, P.4
Everts, V.5
Dankert, J.6
van Alphen, L.7
-
26
-
-
0029812466
-
Bacterial-induced release of inflammatory mediators by bronchial epithelial cells
-
Khair OA, Davies RJ, Devalia JL. Bacterial-induced release of inflammatory mediators by bronchial epithelial cells. Eur Respir J 1996;9:1913-1922.
-
(1996)
Eur Respir J
, vol.9
, pp. 1913-1922
-
-
Khair, O.A.1
Davies, R.J.2
Devalia, J.L.3
-
27
-
-
33846896421
-
Transgenic and gene-targeted mice as models for chronic obstructive pulmonary disease
-
Shapiro SD. Transgenic and gene-targeted mice as models for chronic obstructive pulmonary disease. Eur Respir J 2007;29:375-378.
-
(2007)
Eur Respir J
, vol.29
, pp. 375-378
-
-
Shapiro, S.D.1
-
28
-
-
0037059829
-
Novel cytoplasmic proteins of nontypeable Haemophilus influenzae upregulate human MUC5AC mucin transcription via a positive p38 mitogen-activated protein kinase pathway and a negative phosphoinositide 3-kinase-Akt pathway
-
Wang B, Lim DJ, Han J, Kim YS, Basbaum CB, Li JD. Novel cytoplasmic proteins of nontypeable Haemophilus influenzae upregulate human MUC5AC mucin transcription via a positive p38 mitogen-activated protein kinase pathway and a negative phosphoinositide 3-kinase-Akt pathway. J Biol Chem 2002;277:949-957.
-
(2002)
J Biol Chem
, vol.277
, pp. 949-957
-
-
Wang, B.1
Lim, D.J.2
Han, J.3
Kim, Y.S.4
Basbaum, C.B.5
Li, J.D.6
-
29
-
-
0036529109
-
Lymphocyte proliferative response to P6 of Haemophilus influenzae is associated with relative protection from exacerbations of chronic obstructive pulmonary disease
-
Abe Y, Murphy TF, Sethi S, Faden HS, Dmochowski J, Harabuchi Y, Thanavala YM. Lymphocyte proliferative response to P6 of Haemophilus influenzae is associated with relative protection from exacerbations of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2002;165:967-971.
-
(2002)
Am J Respir Crit Care Med
, vol.165
, pp. 967-971
-
-
Abe, Y.1
Murphy, T.F.2
Sethi, S.3
Faden, H.S.4
Dmochowski, J.5
Harabuchi, Y.6
Thanavala, Y.M.7
-
30
-
-
42049086290
-
Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice
-
Lim JH, Jono H, Koga T, Woo CH, Ishinaga H, Bourne P, Xu H, Ha UH, Xu H, Li JD. Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice. PLoS ONE 2007;2:e1032.
-
(2007)
PLoS ONE
, vol.2
-
-
Lim, J.H.1
Jono, H.2
Koga, T.3
Woo, C.H.4
Ishinaga, H.5
Bourne, P.6
Xu, H.7
Ha, U.H.8
Xu, H.9
Li, J.D.10
-
31
-
-
33845629463
-
Haemophilus haemolyticus: A human respiratory tract commensal to be distinguished from Haemophilus influenzae
-
Murphy TF, Brauer AL, Sethi S, Kilian M, Cai X, Lesse AJ. Haemophilus haemolyticus: a human respiratory tract commensal to be distinguished from Haemophilus influenzae. J Infect Dis 2007;195:81-89.
-
(2007)
J Infect Dis
, vol.195
, pp. 81-89
-
-
Murphy, T.F.1
Brauer, A.L.2
Sethi, S.3
Kilian, M.4
Cai, X.5
Lesse, A.J.6
-
32
-
-
0037094284
-
Effects of intercellular adhesion molecule 1 (ICAM-1) null mutation on radiation-induced pulmonary fibrosis and respiratory insufficiency in mice
-
Hallahan DE, Geng L, Shyr Y. Effects of intercellular adhesion molecule 1 (ICAM-1) null mutation on radiation-induced pulmonary fibrosis and respiratory insufficiency in mice. J Natl Cancer Inst 2002;94:733-741.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 733-741
-
-
Hallahan, D.E.1
Geng, L.2
Shyr, Y.3
-
33
-
-
0018775237
-
Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections
-
Junqueira LC, Bignolas G, Brentani RR. Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections. Histochem J 1979;11:447-455.
-
(1979)
Histochem J
, vol.11
, pp. 447-455
-
-
Junqueira, L.C.1
Bignolas, G.2
Brentani, R.R.3
-
34
-
-
4944265773
-
Mucin is produced by clara cells in the proximal airways of antigen-challenged mice
-
Evans CM, Williams OW, Tuvim MJ, Nigam R, Mixides GP, Blackburn MR, DeMayo FJ, Burns AR, Smith C, Reynolds SD, et al. Mucin is produced by clara cells in the proximal airways of antigen-challenged mice. Am J Respir Cell Mol Biol 2004;31:382-394.
-
(2004)
Am J Respir Cell Mol Biol
, vol.31
, pp. 382-394
-
-
Evans, C.M.1
Williams, O.W.2
Tuvim, M.J.3
Nigam, R.4
Mixides, G.P.5
Blackburn, M.R.6
DeMayo, F.J.7
Burns, A.R.8
Smith, C.9
Reynolds, S.D.10
-
35
-
-
0018679527
-
Morphometry of the human lung: The state of the art after two decades
-
Weibel ER. Morphometry of the human lung: the state of the art after two decades. Bull Eur Physiopathol Respir 1979;15:999-1013.
-
(1979)
Bull Eur Physiopathol Respir
, vol.15
, pp. 999-1013
-
-
Weibel, E.R.1
-
36
-
-
0024895886
-
Distribution analysis of alveolar size by digital imaging
-
Huang YI, Mitzner W. Distribution analysis of alveolar size by digital imaging. Comput Assist Microsc 1989;1:397-409.
-
(1989)
Comput Assist Microsc
, vol.1
, pp. 397-409
-
-
Huang, Y.I.1
Mitzner, W.2
-
37
-
-
2342468107
-
On defining total lung capacity in the mouse
-
Soutiere SE, Mitzner W. On defining total lung capacity in the mouse. J Appl Physiol 2004;96:1658-1664.
-
(2004)
J Appl Physiol
, vol.96
, pp. 1658-1664
-
-
Soutiere, S.E.1
Mitzner, W.2
-
38
-
-
35948940010
-
Central role of Muc5ac expression in mucous metaplasia and its regulation by conserved 59 elements
-
Young HW, Williams OW, Chandra D, Bellinghausen LK, Perez G, Suarez A, Tuvim MJ, Roy MG, Alexander SN, Moghaddam SJ, et al. Central role of Muc5ac expression in mucous metaplasia and its regulation by conserved 59 elements. Am J Respir Cell Mol Biol 2007;37:273-290.
-
(2007)
Am J Respir Cell Mol Biol
, vol.37
, pp. 273-290
-
-
Young, H.W.1
Williams, O.W.2
Chandra, D.3
Bellinghausen, L.K.4
Perez, G.5
Suarez, A.6
Tuvim, M.J.7
Roy, M.G.8
Alexander, S.N.9
Moghaddam, S.J.10
-
39
-
-
33750182181
-
Mucin overproduction in chronic inflammatory lung disease
-
Hauber HP, Foley SC, Hamid Q. Mucin overproduction in chronic inflammatory lung disease. Can Respir J 2006;13:327-335.
-
(2006)
Can Respir J
, vol.13
, pp. 327-335
-
-
Hauber, H.P.1
Foley, S.C.2
Hamid, Q.3
-
40
-
-
0031836613
-
Mucin gene (MUC 2 and MUC 5AC) upregulation by Gram-positive and Gram-negative bacteria
-
Dohrman A, Miyata S, Gallup M, Li JD, Chapelin C, Coste A, Escudier E, Nadel J, Basbaum C. Mucin gene (MUC 2 and MUC 5AC) upregulation by Gram-positive and Gram-negative bacteria. Biochim Biophys Acta 1998;1406:251-259.
-
(1998)
Biochim Biophys Acta
, vol.1406
, pp. 251-259
-
-
Dohrman, A.1
Miyata, S.2
Gallup, M.3
Li, J.D.4
Chapelin, C.5
Coste, A.6
Escudier, E.7
Nadel, J.8
Basbaum, C.9
-
41
-
-
0032549673
-
Cloning of the amino-terminal and 5′-flanking region of the human MUC5AC mucin gene and transcriptional up-regulation by bacterial exoproducts
-
Li D, Gallup M, Fan N, Szymkowski DE, Basbaum CB. Cloning of the amino-terminal and 5′-flanking region of the human MUC5AC mucin gene and transcriptional up-regulation by bacterial exoproducts. J Biol Chem 1998;273:6812-6820.
-
(1998)
J Biol Chem
, vol.273
, pp. 6812-6820
-
-
Li, D.1
Gallup, M.2
Fan, N.3
Szymkowski, D.E.4
Basbaum, C.B.5
-
42
-
-
0030071687
-
Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma
-
Keatings VM, Collins PD, Scott DM, Barnes PJ. Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma. Am J Respir Crit Care Med 1996;153:530-534.
-
(1996)
Am J Respir Crit Care Med
, vol.153
, pp. 530-534
-
-
Keatings, V.M.1
Collins, P.D.2
Scott, D.M.3
Barnes, P.J.4
-
43
-
-
22044450897
-
Matrix metalloproteinase-2 (MMP-2) and MMP-9 in pulmonary pathology
-
Chakrabarti S, Patel KD. Matrix metalloproteinase-2 (MMP-2) and MMP-9 in pulmonary pathology. Exp Lung Res 2005;31:599-621.
-
(2005)
Exp Lung Res
, vol.31
, pp. 599-621
-
-
Chakrabarti, S.1
Patel, K.D.2
-
44
-
-
0034999076
-
Quantitative analysis of inflammatory cells infiltrating the cystic fibrosis airway mucosa
-
Hubeau C, Lorenzato M, Couetil JP, Hubert D, Dusser D, Puchelle E, Gaillard D. Quantitative analysis of inflammatory cells infiltrating the cystic fibrosis airway mucosa. Clin Exp Immunol 2001;124:69-76.
-
(2001)
Clin Exp Immunol
, vol.124
, pp. 69-76
-
-
Hubeau, C.1
Lorenzato, M.2
Couetil, J.P.3
Hubert, D.4
Dusser, D.5
Puchelle, E.6
Gaillard, D.7
-
45
-
-
33845303956
-
Inducible bronchus-associated lymphoid tissue (iBALT) in patients with pulmonary complications of rheumatoid arthritis
-
Rangel-Moreno J, Hartson L, Navarro C, Gaxiola M, Selman M, Randall TD. Inducible bronchus-associated lymphoid tissue (iBALT) in patients with pulmonary complications of rheumatoid arthritis. J Clin Invest 2006;116:3183-3194.
-
(2006)
J Clin Invest
, vol.116
, pp. 3183-3194
-
-
Rangel-Moreno, J.1
Hartson, L.2
Navarro, C.3
Gaxiola, M.4
Selman, M.5
Randall, T.D.6
-
46
-
-
33748669853
-
Role of nontypeable Haemophilus influenzae in exacerbations and progression of chronic obstructive pulmonary disease
-
Eldika N, Sethi S. Role of nontypeable Haemophilus influenzae in exacerbations and progression of chronic obstructive pulmonary disease. Curr Opin Pulm Med 2006;12:118-124.
-
(2006)
Curr Opin Pulm Med
, vol.12
, pp. 118-124
-
-
Eldika, N.1
Sethi, S.2
-
47
-
-
33646675116
-
Pathogenesis of bacterial exacerbations of COPD
-
Veeramachaneni SB, Sethi S. Pathogenesis of bacterial exacerbations of COPD. COPD 2006;3:109-115.
-
(2006)
COPD
, vol.3
, pp. 109-115
-
-
Veeramachaneni, S.B.1
Sethi, S.2
-
48
-
-
34250823515
-
Gene-specific control of inflammation by TLR-induced chromatin modifications
-
Foster SL, Hargreaves DC, Medzhitov R. Gene-specific control of inflammation by TLR-induced chromatin modifications. Nature 2007;447:972-978.
-
(2007)
Nature
, vol.447
, pp. 972-978
-
-
Foster, S.L.1
Hargreaves, D.C.2
Medzhitov, R.3
-
49
-
-
34948886712
-
Adaptive immune cells temper initial innate responses
-
Kim KD, Zhao J, Auh S, Yang X, Du P, Tang H, Fu YX. Adaptive immune cells temper initial innate responses. Nat Med 2007;13:1248-1252.
-
(2007)
Nat Med
, vol.13
, pp. 1248-1252
-
-
Kim, K.D.1
Zhao, J.2
Auh, S.3
Yang, X.4
Du, P.5
Tang, H.6
Fu, Y.X.7
-
50
-
-
0028270358
-
Collagen content of alveolar wall tissue in emphysematous and non-emphysematous lungs
-
Lang MR, Fiaux GW, Gillooly M, Stewart JA, Hulmes DJ, Lamb D. Collagen content of alveolar wall tissue in emphysematous and non-emphysematous lungs. Thorax 1994;49:319-326.
-
(1994)
Thorax
, vol.49
, pp. 319-326
-
-
Lang, M.R.1
Fiaux, G.W.2
Gillooly, M.3
Stewart, J.A.4
Hulmes, D.J.5
Lamb, D.6
-
52
-
-
0037397842
-
Respiratory infections caused by non-typeable Haemophilus influenzae
-
Murphy TF. Respiratory infections caused by non-typeable Haemophilus influenzae. Curr Opin Infect Dis 2003;16:129-134.
-
(2003)
Curr Opin Infect Dis
, vol.16
, pp. 129-134
-
-
Murphy, T.F.1
-
53
-
-
5444253271
-
Nontypeable Haemophilus influenzae lipoprotein P6 induces MUC5AC mucin transcription via TLR2-TAK1-dependent p38 MAPK-AP1 and IKKbeta-IkappaBalpha-NF- kappaB signaling pathways
-
Chen R, Lim JH, Jono H, Gu XX, Kim YS, Basbaum CB, Murphy TF, Li JD. Nontypeable Haemophilus influenzae lipoprotein P6 induces MUC5AC mucin transcription via TLR2-TAK1-dependent p38 MAPK-AP1 and IKKbeta-IkappaBalpha-NF- kappaB signaling pathways. Biochem Biophys Res Commun 2004;324:1087-1094.
-
(2004)
Biochem Biophys Res Commun
, vol.324
, pp. 1087-1094
-
-
Chen, R.1
Lim, J.H.2
Jono, H.3
Gu, X.X.4
Kim, Y.S.5
Basbaum, C.B.6
Murphy, T.F.7
Li, J.D.8
-
54
-
-
8644255162
-
Neutrophil elastase induces mucus cell metaplasia in mouse lung
-
Voynow JA, Fischer BM, Malarkey DE, Burch LH, Wong T, Longphre M, Ho SB, Foster WM. Neutrophil elastase induces mucus cell metaplasia in mouse lung. Am J Physiol Lung Cell Mol Physiol 2004;287:L1293-L1302.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
-
-
Voynow, J.A.1
Fischer, B.M.2
Malarkey, D.E.3
Burch, L.H.4
Wong, T.5
Longphre, M.6
Ho, S.B.7
Foster, W.M.8
-
55
-
-
0034069787
-
Role of neutrophil elastase in hypersecretion during COPD exacerbations, and proposed therapies
-
Nadel JA. Role of neutrophil elastase in hypersecretion during COPD exacerbations, and proposed therapies. Chest 2000;117:386S-389S.
-
(2000)
Chest
, vol.117
-
-
Nadel, J.A.1
-
56
-
-
33847084360
-
A morphometric study of mucins and small airway plugging in cystic fibrosis
-
Burgel PR, Montani D, Danel C, Dusser DJ, Nadel JA. A morphometric study of mucins and small airway plugging in cystic fibrosis. Thorax 2007;62:153-161.
-
(2007)
Thorax
, vol.62
, pp. 153-161
-
-
Burgel, P.R.1
Montani, D.2
Danel, C.3
Dusser, D.J.4
Nadel, J.A.5
-
57
-
-
0042847362
-
Transforming growth factor-beta-Smad signaling pathway negatively regulates non-typeable Haemophilus influenzae-induced MUC5AC mucin transcription via mitogen-activated protein kinase (MAPK) phosphatase-1-dependent inhibition of p38 MAPK
-
Jono H, Xu H, Kai H, Lim DJ, Kim YS, Feng XH, Li JD. Transforming growth factor-beta-Smad signaling pathway negatively regulates non-typeable Haemophilus influenzae-induced MUC5AC mucin transcription via mitogen-activated protein kinase (MAPK) phosphatase-1-dependent inhibition of p38 MAPK. J Biol Chem 2003;278:27811-27819.
-
(2003)
J Biol Chem
, vol.278
, pp. 27811-27819
-
-
Jono, H.1
Xu, H.2
Kai, H.3
Lim, D.J.4
Kim, Y.S.5
Feng, X.H.6
Li, J.D.7
-
58
-
-
0032251330
-
The relationship of chronic mucin secretion to airway disease in normal and CFTR-deficient mice
-
Cressman VL, Hicks EM, Funkhouser WK, Backlund DC, Koller BH. The relationship of chronic mucin secretion to airway disease in normal and CFTR-deficient mice. Am J Respir Cell Mol Biol 1998;19:853-866.
-
(1998)
Am J Respir Cell Mol Biol
, vol.19
, pp. 853-866
-
-
Cressman, V.L.1
Hicks, E.M.2
Funkhouser, W.K.3
Backlund, D.C.4
Koller, B.H.5
-
59
-
-
0033045546
-
Neutrophil elastase increases MUC5AC mRNA and protein expression in respiratory epithelial cells
-
Voynow JA, Young LR, Wang Y, Horger T, Rose MC, Fischer BM. Neutrophil elastase increases MUC5AC mRNA and protein expression in respiratory epithelial cells. Am J Physiol 1999;276:L835-L843.
-
(1999)
Am J Physiol
, vol.276
-
-
Voynow, J.A.1
Young, L.R.2
Wang, Y.3
Horger, T.4
Rose, M.C.5
Fischer, B.M.6
-
60
-
-
24044456312
-
Human neutrophil elastase induces hypersecretion of mucin from well-differentiated human bronchial epithelial cells in vitro via a protein kinase C{delta}-mediated mechanism
-
Park JA, He F, Martin LD, Li Y, Chorley BN, Adler KB. Human neutrophil elastase induces hypersecretion of mucin from well-differentiated human bronchial epithelial cells in vitro via a protein kinase C{delta}-mediated mechanism. Am J Pathol 2005;167:651-661.
-
(2005)
Am J Pathol
, vol.167
, pp. 651-661
-
-
Park, J.A.1
He, F.2
Martin, L.D.3
Li, Y.4
Chorley, B.N.5
Adler, K.B.6
-
61
-
-
24744464353
-
Neutrophil elastase induces MUC5AC mucin production in human airway epithelial cells via a cascade involving protein kinase C, reactive oxygen species, and TNF-alpha-converting enzyme
-
Shao MX, Nadel JA. Neutrophil elastase induces MUC5AC mucin production in human airway epithelial cells via a cascade involving protein kinase C, reactive oxygen species, and TNF-alpha-converting enzyme. J Immunol 2005;175:4009-4016.
-
(2005)
J Immunol
, vol.175
, pp. 4009-4016
-
-
Shao, M.X.1
Nadel, J.A.2
-
62
-
-
13444310932
-
Niflumic acid and MSI-2216 reduce TNF-alpha-induced mucin expression in human airway mucosa
-
Hauber HP, Daigneault P, Frenkiel S, Lavigne F, Hung HL, Levitt RC, Hamid Q. Niflumic acid and MSI-2216 reduce TNF-alpha-induced mucin expression in human airway mucosa. J Allergy Clin Immunol 2005;115:266-271.
-
(2005)
J Allergy Clin Immunol
, vol.115
, pp. 266-271
-
-
Hauber, H.P.1
Daigneault, P.2
Frenkiel, S.3
Lavigne, F.4
Hung, H.L.5
Levitt, R.C.6
Hamid, Q.7
-
63
-
-
0037593635
-
Interleukin-1 beta and tumor necrosis factor-alpha induce MUC5AC overexpression through a mechanism involving ERK/p38 mitogen-activated protein kinases-MSK1-CREB activation in human airway epithelial cells
-
Song KS, Lee WJ, Chung KC, Koo JS, Yang EJ, Choi JY, Yoon JH. Interleukin-1 beta and tumor necrosis factor-alpha induce MUC5AC overexpression through a mechanism involving ERK/p38 mitogen-activated protein kinases-MSK1-CREB activation in human airway epithelial cells. J Biol Chem 2003;278:23243-23250.
-
(2003)
J Biol Chem
, vol.278
, pp. 23243-23250
-
-
Song, K.S.1
Lee, W.J.2
Chung, K.C.3
Koo, J.S.4
Yang, E.J.5
Choi, J.Y.6
Yoon, J.H.7
-
64
-
-
28444435861
-
Chronic exposure to TNF-alpha increases airway mucus gene expression in vivo
-
Busse PJ, Zhang TF, Srivastava K, Lin BP, Schofield B, Sealfon SC, Li XM. Chronic exposure to TNF-alpha increases airway mucus gene expression in vivo. J Allergy Clin Immunol 2005;116:1256-1263.
-
(2005)
J Allergy Clin Immunol
, vol.116
, pp. 1256-1263
-
-
Busse, P.J.1
Zhang, T.F.2
Srivastava, K.3
Lin, B.P.4
Schofield, B.5
Sealfon, S.C.6
Li, X.M.7
-
65
-
-
0036846875
-
Interleukin-13 mediates a fundamental pathway for airway epithelial mucus induced by CD4 T cells and interleukin-9
-
Whittaker L, Niu N, Temann UA, Stoddard A, Flavell RA, Ray A, Homer RJ, Cohn L. Interleukin-13 mediates a fundamental pathway for airway epithelial mucus induced by CD4 T cells and interleukin-9. Am J Respir Cell Mol Biol 2002;27:593-602.
-
(2002)
Am J Respir Cell Mol Biol
, vol.27
, pp. 593-602
-
-
Whittaker, L.1
Niu, N.2
Temann, U.A.3
Stoddard, A.4
Flavell, R.A.5
Ray, A.6
Homer, R.J.7
Cohn, L.8
-
66
-
-
29144479205
-
Allergen-induced peribronchial fibrosis and mucus production mediated by IkappaB kinase beta-dependent genes in airway epithelium
-
Broide DH, Lawrence T, Doherty T, Cho JY, Miller M, McElwain K, McElwain S, Karin M. Allergen-induced peribronchial fibrosis and mucus production mediated by IkappaB kinase beta-dependent genes in airway epithelium. Proc Natl Acad Sci USA 2005;102:17723-17728.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 17723-17728
-
-
Broide, D.H.1
Lawrence, T.2
Doherty, T.3
Cho, J.Y.4
Miller, M.5
McElwain, K.6
McElwain, S.7
Karin, M.8
-
67
-
-
33646458808
-
Airway mucus: From production to secretion
-
Williams OW, Sharafkhaneh A, Kim V, Dickey BF, Evans CM. Airway mucus: from production to secretion. Am J Respir Cell Mol Biol 2006;34:527-536.
-
(2006)
Am J Respir Cell Mol Biol
, vol.34
, pp. 527-536
-
-
Williams, O.W.1
Sharafkhaneh, A.2
Kim, V.3
Dickey, B.F.4
Evans, C.M.5
-
68
-
-
34247607712
-
The safety and efficacy of infliximab in moderate to severe chronic obstructive pulmonary disease
-
Rennard SI, Fogarty C, Kelsen S, Long W, Ramsdell J, Allison J, Mahler D, Saadeh C, Siler T, Snell P, et al. The safety and efficacy of infliximab in moderate to severe chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2007;175:926-934.
-
(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 926-934
-
-
Rennard, S.I.1
Fogarty, C.2
Kelsen, S.3
Long, W.4
Ramsdell, J.5
Allison, J.6
Mahler, D.7
Saadeh, C.8
Siler, T.9
Snell, P.10
-
69
-
-
38049057089
-
TNF-alpha antagonists and the prevention of hospitalisation for chronic obstructive pulmonary disease
-
Suissa S, Ernst P, Hudson M. TNF-alpha antagonists and the prevention of hospitalisation for chronic obstructive pulmonary disease. Pulm Pharmacol Ther 2008;21:234-238.
-
(2008)
Pulm Pharmacol Ther
, vol.21
, pp. 234-238
-
-
Suissa, S.1
Ernst, P.2
Hudson, M.3
-
70
-
-
33846191549
-
Tumour necrosis factor and lymphotoxin A polymorphisms: A relationship with COPD and its progression?
-
Boezen HM, Postma DS. Tumour necrosis factor and lymphotoxin A polymorphisms: a relationship with COPD and its progression? Eur Respir J 2007;29:8-10.
-
(2007)
Eur Respir J
, vol.29
, pp. 8-10
-
-
Boezen, H.M.1
Postma, D.S.2
-
71
-
-
33846204316
-
Tumour necrosis factor and lymphotoxin A polymorphisms and lung function in smokers
-
Tanaka G, Sandford AJ, Burkett K, Connett JE, Anthonisen NR, Pare PD, He JQ. Tumour necrosis factor and lymphotoxin A polymorphisms and lung function in smokers. Eur Respir J 2007;29:34-41.
-
(2007)
Eur Respir J
, vol.29
, pp. 34-41
-
-
Tanaka, G.1
Sandford, A.J.2
Burkett, K.3
Connett, J.E.4
Anthonisen, N.R.5
Pare, P.D.6
He, J.Q.7
-
72
-
-
0029114675
-
Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis: A mouse model of progressive pulmonary fibrosis
-
Miyazaki Y, Araki K, Vesin C, Garcia I, Kapanci Y, Whitsett JA, Piguet PF, Vassalli P. Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis: a mouse model of progressive pulmonary fibrosis. J Clin Invest 1995;96:250-259.
-
(1995)
J Clin Invest
, vol.96
, pp. 250-259
-
-
Miyazaki, Y.1
Araki, K.2
Vesin, C.3
Garcia, I.4
Kapanci, Y.5
Whitsett, J.A.6
Piguet, P.F.7
Vassalli, P.8
-
73
-
-
1842504010
-
Lymphoid tissue and emphysema in the lungs of transgenic mice inducibly expressing tumor necrosis factor-alpha
-
Vuillemenot BR, Rodriguez JF, Hoyle GW. Lymphoid tissue and emphysema in the lungs of transgenic mice inducibly expressing tumor necrosis factor-alpha. Am J Respir Cell Mol Biol 2004;30:438-448.
-
(2004)
Am J Respir Cell Mol Biol
, vol.30
, pp. 438-448
-
-
Vuillemenot, B.R.1
Rodriguez, J.F.2
Hoyle, G.W.3
-
74
-
-
0035859841
-
Left ventricular remodeling in transgenic mice with cardiac restricted overexpression of tumor necrosis factor
-
Sivasubramanian N, Coker ML, Kurrelmeyer KM, MacLellan WR, DeMayo FJ, Spinale FG, Mann DL. Left ventricular remodeling in transgenic mice with cardiac restricted overexpression of tumor necrosis factor. Circulation 2001;104:826-831.
-
(2001)
Circulation
, vol.104
, pp. 826-831
-
-
Sivasubramanian, N.1
Coker, M.L.2
Kurrelmeyer, K.M.3
MacLellan, W.R.4
DeMayo, F.J.5
Spinale, F.G.6
Mann, D.L.7
-
75
-
-
0029793254
-
Immunohistochemical localization of mouse Clara cell 10-KD protein using antibodies raised against the recombinant protein
-
Ray MK, Wang G, Barrish J, Finegold MJ, DeMayo FJ. Immunohistochemical localization of mouse Clara cell 10-KD protein using antibodies raised against the recombinant protein. J Histochem Cytochem 1996;44:919-927.
-
(1996)
J Histochem Cytochem
, vol.44
, pp. 919-927
-
-
Ray, M.K.1
Wang, G.2
Barrish, J.3
Finegold, M.J.4
DeMayo, F.J.5
|