메뉴 건너뛰기




Volumn 124, Issue 7, 2011, Pages 1007-1016

Mitotic spindle misorientation in cancer - out of alignment and into the fire

Author keywords

APC; E Cadherin; Spindle alignment; Spindle orientation; VHL

Indexed keywords

APC PROTEIN; TUMOR SUPPRESSOR PROTEIN; UVOMORULIN; VON HIPPEL LINDAU PROTEIN;

EID: 79953156769     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.081406     Document Type: Article
Times cited : (119)

References (177)
  • 1
    • 77954922985 scopus 로고    scopus 로고
    • Stem cells in cancer: instigators and propagators?
    • Alison, M. R., Shahriar, I. and Wright, N. A. (2010). Stem cells in cancer: instigators and propagators? J. Cell Sci. 123, 2357-2368.
    • (2010) J. Cell Sci. , vol.123 , pp. 2357-2368
    • Alison, M.R.1    Shahriar, I.2    Wright, N.A.3
  • 2
    • 47949122502 scopus 로고    scopus 로고
    • Hereditary colorectal cancer syndromes: familial adenomatous polyposis and lynch syndrome
    • Al-Sukhni, W., Aronson, M. and Gallinger, S. (2008). Hereditary colorectal cancer syndromes: familial adenomatous polyposis and lynch syndrome. Surg. Clin. North Am. 88, 819-844.
    • (2008) Surg. Clin. North Am. , vol.88 , pp. 819-844
    • Al-Sukhni, W.1    Aronson, M.2    Gallinger, S.3
  • 3
    • 24944575221 scopus 로고    scopus 로고
    • The orientation of cell divisions determines the shape of Drosophila organs
    • Baena-López, L. A., Baonza, A. and García-Bellido, A. (2005). The orientation of cell divisions determines the shape of Drosophila organs. Curr. Biol. 15, 1640-1644.
    • (2005) Curr. Biol. , vol.15 , pp. 1640-1644
    • Baena-López, L.A.1    Baonza, A.2    García-Bellido, A.3
  • 7
    • 70349417837 scopus 로고    scopus 로고
    • Microtubule plus-end and minus-end capture at adherens junctions is involved in the assembly of apico-basal arrays in polarised epithelial cells
    • Bellett, G., Carter, J. M., Keynton, J., Goldspink, D., James, C., Moss, D. K. and Mogensen, M. M. (2009). Microtubule plus-end and minus-end capture at adherens junctions is involved in the assembly of apico-basal arrays in polarised epithelial cells. Cell Motil. Cytoskeleton 66, 893-908.
    • (2009) Cell Motil. Cytoskeleton , vol.66 , pp. 893-908
    • Bellett, G.1    Carter, J.M.2    Keynton, J.3    Goldspink, D.4    James, C.5    Moss, D.K.6    Mogensen, M.M.7
  • 9
    • 4344648897 scopus 로고    scopus 로고
    • Dare to be different: asymmetric cell division in Drosophila, C. elegans and vertebrates
    • Betschinger, J. and Knoblich, J. A. (2004). Dare to be different: asymmetric cell division in Drosophila, C. elegans and vertebrates. Curr. Biol. 14, R674-R685.
    • (2004) Curr. Biol. , vol.14
    • Betschinger, J.1    Knoblich, J.A.2
  • 10
    • 33646027006 scopus 로고    scopus 로고
    • Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells
    • Betschinger, J., Mechtler, K. and Knoblich, J. A. (2006). Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells. Cell 124, 1241-1253.
    • (2006) Cell , vol.124 , pp. 1241-1253
    • Betschinger, J.1    Mechtler, K.2    Knoblich, J.A.3
  • 11
    • 0034644526 scopus 로고    scopus 로고
    • Linking colorectal cancer to Wnt signaling
    • Bienz, M. and Clevers, H. (2000). Linking colorectal cancer to Wnt signaling. Cell 103, 311-320.
    • (2000) Cell , vol.103 , pp. 311-320
    • Bienz, M.1    Clevers, H.2
  • 13
    • 33846460770 scopus 로고    scopus 로고
    • Spindle regulation in neural precursors of flies and mammals
    • Buchman, J. J. and Tsai, L. H. (2007). Spindle regulation in neural precursors of flies and mammals. Nat. Rev. Neurosci. 8, 89-100.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 89-100
    • Buchman, J.J.1    Tsai, L.H.2
  • 14
    • 67650240369 scopus 로고    scopus 로고
    • Apical/basal spindle orientation is required for neuroblast homeostasis and neuronal differentiation in Drosophila
    • Cabernard, C. and Doe, C. Q. (2009). Apical/basal spindle orientation is required for neuroblast homeostasis and neuronal differentiation in Drosophila. Dev. Cell 17, 134-141.
    • (2009) Dev. Cell , vol.17 , pp. 134-141
    • Cabernard, C.1    Doe, C.Q.2
  • 15
    • 34748818856 scopus 로고    scopus 로고
    • APC mutations lead to cytokinetic failures in vitro and tetraploid genotypes in Min mice
    • Caldwell, C. M., Green, R. A. and Kaplan, K. B. (2007). APC mutations lead to cytokinetic failures in vitro and tetraploid genotypes in Min mice. J. Cell Biol. 178, 1109-1120.
    • (2007) J. Cell Biol. , vol.178 , pp. 1109-1120
    • Caldwell, C.M.1    Green, R.A.2    Kaplan, K.B.3
  • 16
    • 77956460390 scopus 로고    scopus 로고
    • Environmental control of invasiveness and metastatic dissemination of tumor cells: the role of tumor cell-host cell interactions
    • Calorini, L. and Bianchini, F. (2010). Environmental control of invasiveness and metastatic dissemination of tumor cells: the role of tumor cell-host cell interactions. Cell Comm. Signal. 8, 24.
    • (2010) Cell Comm. Signal. , vol.8 , pp. 24
    • Calorini, L.1    Bianchini, F.2
  • 17
    • 32944457801 scopus 로고    scopus 로고
    • von Hippel-Lindau tumor suppressor protein regulates the assembly of intercellular junctions in renal cancer cells through hypoxia-inducible factor independent mechanisms
    • Calzada, M. J., Esteban, M. A., Feijoo-Cuaresma, M., Castellanos, M. C., Naranjo-Suárez, S., Temes, E., Méndez, F., Yánez-Mo, M., Ohh, M. and Landázuri, M. O. (2006). von Hippel-Lindau tumor suppressor protein regulates the assembly of intercellular junctions in renal cancer cells through hypoxia-inducible factor independent mechanisms. Cancer Res. 66, 1553-1560.
    • (2006) Cancer Res , vol.66 , pp. 1553-1560
    • Calzada, M.J.1    Esteban, M.A.2    Feijoo-Cuaresma, M.3    Castellanos, M.C.4    Naranjo-Suárez, S.5    Temes, E.6    Méndez, F.7    Yánez-Mo, M.8    Ohh, M.9    Landázuri, M.O.10
  • 18
    • 33846065117 scopus 로고    scopus 로고
    • Depletion of E-cadherin disrupts establishment but not maintenance of cell junctions in Madin-Darby canine kidney epithelial cells
    • Capaldo, C. T. and Macara, I. G. (2007). Depletion of E-cadherin disrupts establishment but not maintenance of cell junctions in Madin-Darby canine kidney epithelial cells. Mol. Biol. Cell 18, 189-200.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 189-200
    • Capaldo, C.T.1    Macara, I.G.2
  • 19
    • 49649092093 scopus 로고    scopus 로고
    • Centrosome dysfunction in Drosophila neural stem cells causes tumors that are not due to genome instability
    • Castellanos, E., Dominguez, P. and Gonzalez, C. (2008). Centrosome dysfunction in Drosophila neural stem cells causes tumors that are not due to genome instability. Curr. Biol. 18, 1209-1214.
    • (2008) Curr. Biol. , vol.18 , pp. 1209-1214
    • Castellanos, E.1    Dominguez, P.2    Gonzalez, C.3
  • 20
    • 27144555447 scopus 로고    scopus 로고
    • Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster
    • Caussinus, E. and Gonzalez, C. (2005). Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster. Nat. Genet. 37, 1125-1129.
    • (2005) Nat. Genet. , vol.37 , pp. 1125-1129
    • Caussinus, E.1    Gonzalez, C.2
  • 21
    • 0035425836 scopus 로고    scopus 로고
    • Asymmetric segregation of Numb in retinal development and the influence of the pigmented epithelium
    • Cayouette, M., Whitmore, A. V., Jeffery, G. and Raff, M. (2001). Asymmetric segregation of Numb in retinal development and the influence of the pigmented epithelium. J. Neurosci. 21, 5643-5651.
    • (2001) J. Neurosci. , vol.21 , pp. 5643-5651
    • Cayouette, M.1    Whitmore, A.V.2    Jeffery, G.3    Raff, M.4
  • 22
    • 34547609385 scopus 로고    scopus 로고
    • Disruption of tumor cell adhesion promotes angiogenic switch and progression to micrometastasis in RAF-driven murine lung cancer
    • Ceteci, F., Ceteci, S., Karreman, C., Kramer, B. W., Asan, E., Götz, R. and Rapp, U. R. (2007). Disruption of tumor cell adhesion promotes angiogenic switch and progression to micrometastasis in RAF-driven murine lung cancer. Cancer Cell 12, 145-159.
    • (2007) Cancer Cell , vol.12 , pp. 145-159
    • Ceteci, F.1    Ceteci, S.2    Karreman, C.3    Kramer, B.W.4    Asan, E.5    Götz, R.6    Rapp, U.R.7
  • 23
    • 60949102816 scopus 로고    scopus 로고
    • A little CIN may cost a lot: revisiting aneuploidy and cancer
    • Chandhok, N. S. and Pellman, D. (2009). A little CIN may cost a lot: revisiting aneuploidy and cancer. Curr. Opin. Genet. Dev. 19, 74-81.
    • (2009) Curr. Opin. Genet. Dev. , vol.19 , pp. 74-81
    • Chandhok, N.S.1    Pellman, D.2
  • 24
    • 0033769661 scopus 로고    scopus 로고
    • Cadherin-mediated regulation of microtubule dynamics
    • Chausovsky, A., Bershadsky, A. D. and Borisy, G. G. (2000). Cadherin-mediated regulation of microtubule dynamics. Nat. Cell Biol. 2, 797-804.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 797-804
    • Chausovsky, A.1    Bershadsky, A.D.2    Borisy, G.G.3
  • 25
    • 0029080470 scopus 로고
    • Cleavage orientation and the asymmetric inheritance of Notch1 immunoreactivity in mammalian neurogenesis
    • Chenn, A. and McConnell, S. K. (1995). Cleavage orientation and the asymmetric inheritance of Notch1 immunoreactivity in mammalian neurogenesis. Cell 82, 631-641.
    • (1995) Cell , vol.82 , pp. 631-641
    • Chenn, A.1    McConnell, S.K.2
  • 27
    • 77954564655 scopus 로고    scopus 로고
    • Matricellular proteins: from homeostasis to inflammation, cancer, and metastasis
    • Chiodoni, C., Colombo, M. P. and Sangaletti, S. (2010). Matricellular proteins: from homeostasis to inflammation, cancer, and metastasis. Cancer Metastasis Rev. 29, 295-307.
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 295-307
    • Chiodoni, C.1    Colombo, M.P.2    Sangaletti, S.3
  • 28
    • 33646346143 scopus 로고    scopus 로고
    • Prototypical type I E-cadherin and type II cadherin-7 mediate very distinct adhesiveness through their extracellular domains
    • Chu, Y. S., Eder, O., Thomas, W. A., Simcha, I., Pincet, F., Ben-Ze'ev, A., Perez, E., Thiery, J. P. and Dufour, S. (2005). Prototypical type I E-cadherin and type II cadherin-7 mediate very distinct adhesiveness through their extracellular domains. J. Biol. Chem. 281, 2901-2910.
    • (2005) J. Biol. Chem. , vol.281 , pp. 2901-2910
    • Chu, Y.S.1    Eder, O.2    Thomas, W.A.3    Simcha, I.4    Pincet, F.5    Ben-Ze'ev, A.6    Perez, E.7    Thiery, J.P.8    Dufour, S.9
  • 29
    • 77949881462 scopus 로고    scopus 로고
    • The PI3K pathway as drug target in human cancer
    • Courtney, K. D., Corcoran, R. B. and Engelman, J. A. (2010). The PI3K pathway as drug target in human cancer. J. Clin. Oncol. 28, 1075-1083.
    • (2010) J. Clin. Oncol. , vol.28 , pp. 1075-1083
    • Courtney, K.D.1    Corcoran, R.B.2    Engelman, J.A.3
  • 30
    • 8344221351 scopus 로고    scopus 로고
    • Asymmetric cell division in C. elegans: cortical polarity and spindle positioning
    • Cowan, C. R. and Hyman, A. A. (2004). Asymmetric cell division in C. elegans: cortical polarity and spindle positioning. Annu. Rev. Cell Dev. Biol. 20, 427-453.
    • (2004) Annu. Rev. Cell Dev. Biol. , vol.20 , pp. 427-453
    • Cowan, C.R.1    Hyman, A.A.2
  • 31
    • 69949106214 scopus 로고    scopus 로고
    • Cadherin adhesion receptors orient the mitotic spindle during symmetric cell division in mammalian epithelia
    • den Elzen, N., Buttery, C. V., Maddugoda, M. P., Ren, G. and Yap, A. S. (2009). Cadherin adhesion receptors orient the mitotic spindle during symmetric cell division in mammalian epithelia. Mol. Biol. Cell 20, 3740-3750.
    • (2009) Mol. Biol. Cell , vol.20 , pp. 3740-3750
    • den Elzen, N.1    Buttery, C.V.2    Maddugoda, M.P.3    Ren, G.4    Yap, A.S.5
  • 32
    • 0031239690 scopus 로고    scopus 로고
    • Spectrosomes and fusomes anchor mitotic spindles during asymmetric germ cell divisions and facilitate the formation of a polarized microtubule array for oocyte specification in Drosophila
    • Deng, W. and Lin, H. (1997). Spectrosomes and fusomes anchor mitotic spindles during asymmetric germ cell divisions and facilitate the formation of a polarized microtubule array for oocyte specification in Drosophila. Dev. Biol. 189, 79-94.
    • (1997) Dev. Biol. , vol.189 , pp. 79-94
    • Deng, W.1    Lin, H.2
  • 33
  • 34
    • 0033561521 scopus 로고    scopus 로고
    • Dominant negative effect of the APC1309 mutation: a possible explanation for genotype-phenotype correlations in familial adenomatous polyposis
    • Dihlmann, S., Gebert, J., Siermann, A., Herfarth, C. and von Knebel Doeberitz, M. (1999). Dominant negative effect of the APC1309 mutation: a possible explanation for genotype-phenotype correlations in familial adenomatous polyposis. Cancer Res. 59, 1857-1860.
    • (1999) Cancer Res , vol.59 , pp. 1857-1860
    • Dihlmann, S.1    Gebert, J.2    Siermann, A.3    Herfarth, C.4    von Knebel Doeberitz, M.5
  • 35
  • 36
    • 0034800271 scopus 로고    scopus 로고
    • Hereditary diffuse gastric cancer
    • Dunbier, A. and Guilford, P. (2001). Hereditary diffuse gastric cancer. Adv. Cancer Res. 83, 55-65.
    • (2001) Adv. Cancer Res. , vol.83 , pp. 55-65
    • Dunbier, A.1    Guilford, P.2
  • 37
    • 34250681643 scopus 로고    scopus 로고
    • Regulation of spindle orientation and neural stem cell fate in the Drosophila optic lobe
    • Egger, B., Boone, J. Q., Stevens, N. R., Brand, A. H. and Doe, C. Q. (2007). Regulation of spindle orientation and neural stem cell fate in the Drosophila optic lobe. Neural Dev. 2, 1.
    • (2007) Neural Dev , vol.2 , pp. 1
    • Egger, B.1    Boone, J.Q.2    Stevens, N.R.3    Brand, A.H.4    Doe, C.Q.5
  • 38
    • 77956600380 scopus 로고    scopus 로고
    • Notch regulates the switch from symmetric to asymmetric neural stem cell division in the Drosophila optic lobe
    • Egger, B., Gold, K. S. and Brand, A. H. (2010). Notch regulates the switch from symmetric to asymmetric neural stem cell division in the Drosophila optic lobe. Development 137, 2981-2987.
    • (2010) Development , vol.137 , pp. 2981-2987
    • Egger, B.1    Gold, K.S.2    Brand, A.H.3
  • 41
    • 24944577909 scopus 로고    scopus 로고
    • Cdc42 and Par6-PKCzeta regulate the spatially localized association of Dlg1 and APC to control cell polarization
    • Etienne-Manneville, S., Manneville, J. B., Nicholls, S., Ferenczi, M. A. and Hall, A. (2005). Cdc42 and Par6-PKCzeta regulate the spatially localized association of Dlg1 and APC to control cell polarization. J. Cell Biol. 170, 895-901.
    • (2005) J. Cell Biol. , vol.170 , pp. 895-901
    • Etienne-Manneville, S.1    Manneville, J.B.2    Nicholls, S.3    Ferenczi, M.A.4    Hall, A.5
  • 44
    • 34047276624 scopus 로고    scopus 로고
    • Integrin signaling regulates spindle orientation in Drosophila to preserve the follicular-epithelium monolayer
    • Fernández-Miñán, A., Martín-Bermudo, M. D. and González-Reyes, A. (2007). Integrin signaling regulates spindle orientation in Drosophila to preserve the follicular-epithelium monolayer. Curr. Biol. 17, 683-688.
    • (2007) Curr. Biol. , vol.17 , pp. 683-688
    • Fernández-Miñán, A.1    Martín-Bermudo, M.D.2    González-Reyes, A.3
  • 46
    • 0032417068 scopus 로고    scopus 로고
    • Benign breast changes and the risk for subsequent breast cancer: an update of the 1985 consensus statement. Cancer committee of the College of American Pathologists
    • Fitzgibbons, P. L., Henson, D. E. and Hutter, R. V. (1998). Benign breast changes and the risk for subsequent breast cancer: an update of the 1985 consensus statement. Cancer committee of the College of American Pathologists. Arch. Pathol. Lab. Med. 122, 1053-1055.
    • (1998) Arch. Pathol. Lab. Med. , vol.122 , pp. 1053-1055
    • Fitzgibbons, P.L.1    Henson, D.E.2    Hutter, R.V.3
  • 49
    • 0034902674 scopus 로고    scopus 로고
    • Disease model: familial adenomatous polyposis
    • Fodde, R. and Smits, R. (2001). Disease model: familial adenomatous polyposis. Trends Mol. Med. 7, 369-373.
    • (2001) Trends Mol. Med. , vol.7 , pp. 369-373
    • Fodde, R.1    Smits, R.2
  • 51
    • 0033407456 scopus 로고    scopus 로고
    • Von Hippel-Lindau syndrome. A pleomorphic condition
    • Friedrich, C. A. (1999). Von Hippel-Lindau syndrome. A pleomorphic condition. Cancer 86, 2478-2482.
    • (1999) Cancer , vol.86 , pp. 2478-2482
    • Friedrich, C.A.1
  • 52
    • 0029881977 scopus 로고    scopus 로고
    • Abnormal centrosome amplification in the absence of p53
    • Fukasawa, K., Choi, T., Kuriyama, R., Rulong, S. and Vande Woude, G. F. (1996). Abnormal centrosome amplification in the absence of p53. Science 271, 1744-1747.
    • (1996) Science , vol.271 , pp. 1744-1747
    • Fukasawa, K.1    Choi, T.2    Kuriyama, R.3    Rulong, S.4    Vande Woude, G.F.5
  • 53
    • 0035032565 scopus 로고    scopus 로고
    • The role of centrosomes and astral microtubules during asymmetric division of Drosophila neuroblasts
    • Giansanti, M. G., Gatti, M. and Bonaccorsi, S. (2001). The role of centrosomes and astral microtubules during asymmetric division of Drosophila neuroblasts. Development 128, 1137-1145.
    • (2001) Development , vol.128 , pp. 1137-1145
    • Giansanti, M.G.1    Gatti, M.2    Bonaccorsi, S.3
  • 54
    • 0842331360 scopus 로고    scopus 로고
    • Cleavage furrow positioning
    • Glotzer, M. (2004). Cleavage furrow positioning. J. Cell Biol. 164, 347-351.
    • (2004) J. Cell Biol. , vol.164 , pp. 347-351
    • Glotzer, M.1
  • 56
    • 0342265157 scopus 로고    scopus 로고
    • Cytoplasmic dynein is required for distinct aspects of MTOC positioning, including centrosome separation, in the one cell stage Caenorhabditis elegans embryo
    • Gönczy, P., Pichler, S., Kirkham, M. and Hyman, A. A. (1999). Cytoplasmic dynein is required for distinct aspects of MTOC positioning, including centrosome separation, in the one cell stage Caenorhabditis elegans embryo. J. Cell Biol. 147, 135-150.
    • (1999) J. Cell Biol. , vol.147 , pp. 135-150
    • Gönczy, P.1    Pichler, S.2    Kirkham, M.3    Hyman, A.A.4
  • 57
    • 34249018619 scopus 로고    scopus 로고
    • Spindle orientation, asymmetric division and tumour suppression in Drosophila stem cells
    • Gonzalez, C. (2007). Spindle orientation, asymmetric division and tumour suppression in Drosophila stem cells. Nat. Rev. Genet. 8, 462-472.
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 462-472
    • Gonzalez, C.1
  • 58
    • 26244463198 scopus 로고    scopus 로고
    • APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment
    • Green, R. A., Wollman, R. and Kaplan, K. B. (2005). APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment. Mol. Biol. Cell 16, 4609-4622.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 4609-4622
    • Green, R.A.1    Wollman, R.2    Kaplan, K.B.3
  • 59
    • 0037079003 scopus 로고    scopus 로고
    • Rules for making human tumor cells
    • Hahn, W. C. and Weinberg, R. A. (2002). Rules for making human tumor cells. N. Eng. J. Med. 347, 1593-1603.
    • (2002) N. Eng. J. Med. , vol.347 , pp. 1593-1603
    • Hahn, W.C.1    Weinberg, R.A.2
  • 60
    • 0036108620 scopus 로고    scopus 로고
    • Cadherin and catenin alterations in human cancer
    • Hajra, K. M. and Fearon, E. R. (2002). Cadherin and catenin alterations in human cancer. Genes Chromosomes Cancer 34, 255-268.
    • (2002) Genes Chromosomes Cancer , vol.34 , pp. 255-268
    • Hajra, K.M.1    Fearon, E.R.2
  • 61
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D. and Weinberg, R. A. (2000). The hallmarks of cancer. Cell 100, 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 62
    • 0037223823 scopus 로고    scopus 로고
    • Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL
    • Hergovich, A., Lisztwan, J., Barry, R., Ballschmieter, P. and Krek, W. (2003). Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL. Nat. Cell Biol. 5, 64-70.
    • (2003) Nat. Cell Biol. , vol.5 , pp. 64-70
    • Hergovich, A.1    Lisztwan, J.2    Barry, R.3    Ballschmieter, P.4    Krek, W.5
  • 63
    • 33746472918 scopus 로고    scopus 로고
    • Priming-dependent phosphorylation and regulation of the tumor suppressor pVHL by glycogen synthase kinase 3
    • Hergovich, A., Lisztwan, J., Thoma, C. R., Wirbelauer, C., Barry, R. E. and Krek, W. (2006). Priming-dependent phosphorylation and regulation of the tumor suppressor pVHL by glycogen synthase kinase 3. Mol. Biol. Cell 26, 5784-5796.
    • (2006) Mol. Biol. Cell , vol.26 , pp. 5784-5796
    • Hergovich, A.1    Lisztwan, J.2    Thoma, C.R.3    Wirbelauer, C.4    Barry, R.E.5    Krek, W.6
  • 64
    • 77952187795 scopus 로고    scopus 로고
    • Tumor suppressor interactions with microtubules: keeping cell polarity and cell division on track
    • Hernandez, P. and Tirnauer, J. S. (2010). Tumor suppressor interactions with microtubules: keeping cell polarity and cell division on track. Dis. Model. Mech. 3, 304-315.
    • (2010) Dis. Model. Mech. , vol.3 , pp. 304-315
    • Hernandez, P.1    Tirnauer, J.S.2
  • 65
    • 36349005441 scopus 로고    scopus 로고
    • KCl cotransporter-3 down-regulates E-cadherin/betacatenin complex to promote epithelial-mesenchymal transition
    • Hsu, Y. M., Chen, Y. F., Chou, C. Y., Tang, M. J., Chen, J. H., Wilkins, R. J., Ellory, J. C. and Shen, M. R. (2007). KCl cotransporter-3 down-regulates E-cadherin/betacatenin complex to promote epithelial-mesenchymal transition. Cancer Res. 67, 11064-11073.
    • (2007) Cancer Res , vol.67 , pp. 11064-11073
    • Hsu, Y.M.1    Chen, Y.F.2    Chou, C.Y.3    Tang, M.J.4    Chen, J.H.5    Wilkins, R.J.6    Ellory, J.C.7    Shen, M.R.8
  • 66
    • 67449093573 scopus 로고    scopus 로고
    • Hereditary diffuse gastric cancer: a manifestation of lost cell polarity
    • Humar, B. and Guilford, P. (2009). Hereditary diffuse gastric cancer: a manifestation of lost cell polarity. Cancer Sci. 100, 1151-1157.
    • (2009) Cancer Sci , vol.100 , pp. 1151-1157
    • Humar, B.1    Guilford, P.2
  • 67
  • 69
    • 58149191544 scopus 로고    scopus 로고
    • Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis
    • Jaffe, A. B., Kaji, N., Durgan, J. and Hall, A. (2008). Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis. J. Cell Biol. 183, 625-633.
    • (2008) J. Cell Biol. , vol.183 , pp. 625-633
    • Jaffe, A.B.1    Kaji, N.2    Durgan, J.3    Hall, A.4
  • 70
    • 0026561134 scopus 로고
    • Electron microscopic observations on the maintenance of the tight junction during cell division in the epithelium of the mouse small intestine
    • Jinguji, Y. and Ishikawa, H. (1992). Electron microscopic observations on the maintenance of the tight junction during cell division in the epithelium of the mouse small intestine. Cell Struct. Funct. 17, 27-37.
    • (1992) Cell Struct. Funct. , vol.17 , pp. 27-37
    • Jinguji, Y.1    Ishikawa, H.2
  • 71
    • 0027979618 scopus 로고
    • The differential diagnosis of prostatic carcinoma. Its distinction from premalignant and pseudocarcinomatous lesions of the prostate gland
    • Jones, E. C. and Young, R. H. (1994). The differential diagnosis of prostatic carcinoma. Its distinction from premalignant and pseudocarcinomatous lesions of the prostate gland. Am. J. Clin. Pathol. 101, 48-64.
    • (1994) Am. J. Clin. Pathol. , vol.101 , pp. 48-64
    • Jones, E.C.1    Young, R.H.2
  • 72
    • 54549113030 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer
    • Kaelin, W. G., Jr (2008). The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer. Nat. Rev. Cancer 8, 865-873.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 865-873
    • Kaelin Jr., W.G.1
  • 73
    • 0033788487 scopus 로고    scopus 로고
    • Rotation and asymmetry of the mitotic spindle direct asymmetric cell division in the developing central nervous system
    • Kaltschmitdt, J. A., Davidson, C. M., Brown, N. H. and Brand, A. H. (2000). Rotation and asymmetry of the mitotic spindle direct asymmetric cell division in the developing central nervous system. Nat. Cell Biol. 2, 7-12.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 7-12
    • Kaltschmitdt, J.A.1    Davidson, C.M.2    Brown, N.H.3    Brand, A.H.4
  • 75
    • 0037341566 scopus 로고    scopus 로고
    • Mutated APC and Asef are involved in the migration of colorectal tumour cells
    • Kawasaki, Y., Sato, R. and Akiyama, T. (2003). Mutated APC and Asef are involved in the migration of colorectal tumour cells. Nat. Cell Biol. 5, 211-215.
    • (2003) Nat. Cell Biol. , vol.5 , pp. 211-215
    • Kawasaki, Y.1    Sato, R.2    Akiyama, T.3
  • 77
    • 0030712193 scopus 로고    scopus 로고
    • The distribution and requirements of microtubules and microfilaments during fertilization and parthenogenesis in pig oocytes
    • Kim, N. H., Chung, K. S. and Day, B. N. (1997). The distribution and requirements of microtubules and microfilaments during fertilization and parthenogenesis in pig oocytes. J. Reprod. Fertil. 111, 143-149.
    • (1997) J. Reprod. Fertil. , vol.111 , pp. 143-149
    • Kim, N.H.1    Chung, K.S.2    Day, B.N.3
  • 78
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • Kinzler, K. W. and Vogelstein, B. (1996). Lessons from hereditary colorectal cancer. Cell 87, 159-170.
    • (1996) Cell , vol.87 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 79
    • 0030666655 scopus 로고    scopus 로고
    • Mechanisms of asymmetric cell division during animal development
    • Knoblich, J. A. (1997). Mechanisms of asymmetric cell division during animal development. Curr. Opin. Cell Biol. 9, 833-841.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 833-841
    • Knoblich, J.A.1
  • 80
    • 39149130360 scopus 로고    scopus 로고
    • Mechanisms of asymmetric stem cell division
    • Knoblich, J. A. (2008). Mechanisms of asymmetric stem cell division. Cell 132, 583-597.
    • (2008) Cell , vol.132 , pp. 583-597
    • Knoblich, J.A.1
  • 81
    • 3042541528 scopus 로고    scopus 로고
    • Asymmetric distribution of the apical plasma membrane during neurogenic divisions of mammalian neuroepithelial cells
    • Kosodo, Y., Röpera, K., Haubensakac, W., Marzesco, A.-M., Corbeil, D. and Huttner, W. B. (2004). Asymmetric distribution of the apical plasma membrane during neurogenic divisions of mammalian neuroepithelial cells. EMBO J. 23, 2314-2324.
    • (2004) EMBO J , vol.23 , pp. 2314-2324
    • Kosodo, Y.1    Röpera, K.2    Haubensakac, W.3    Marzesco, A.-M.4    Corbeil, D.5    Huttner, W.B.6
  • 83
    • 33645090169 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1-dependent repression of Ecadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B
    • Krishnamachary, B., Zagzag, D., Nagasawa, H., Rainey, K., Okuyama, H., Baek, J. H. and Semenza, G. L. (2006). Hypoxia-inducible factor-1-dependent repression of Ecadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B. Cancer Res. 66, 2725-2731.
    • (2006) Cancer Res , vol.66 , pp. 2725-2731
    • Krishnamachary, B.1    Zagzag, D.2    Nagasawa, H.3    Rainey, K.4    Okuyama, H.5    Baek, J.H.6    Semenza, G.L.7
  • 84
    • 33947177629 scopus 로고    scopus 로고
    • Lack of adenomatous polyposis coli protein correlates with a decrease in cell migration and overall changes in microtubule stability
    • Kroboth, K., Newton, I. P., Kita, K., Dikovskaya, D., Zumbrunn, J., Waterman-Storer, C. M. and Näthke, I. S. (2007). Lack of adenomatous polyposis coli protein correlates with a decrease in cell migration and overall changes in microtubule stability. Mol. Biol. Cell 18, 910-918.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 910-918
    • Kroboth, K.1    Newton, I.P.2    Kita, K.3    Dikovskaya, D.4    Zumbrunn, J.5    Waterman-Storer, C.M.6    Näthke, I.S.7
  • 86
    • 24644494270 scopus 로고    scopus 로고
    • Asymmetric cell divisions promote stratification and differentiation of mammalian skin
    • Lechler, T. and Fuchs, E. (2005). Asymmetric cell divisions promote stratification and differentiation of mammalian skin. Nature 437, 275-280.
    • (2005) Nature , vol.437 , pp. 275-280
    • Lechler, T.1    Fuchs, E.2
  • 87
    • 33645525794 scopus 로고    scopus 로고
    • Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal
    • Lee, C. Y., Wilkinson, B. D., Siegrist, S. E., Wharton, R. P. and Doe, C. Q. (2006). Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal. Dev. Cell 10, 441-449.
    • (2006) Dev. Cell , vol.10 , pp. 441-449
    • Lee, C.Y.1    Wilkinson, B.D.2    Siegrist, S.E.3    Wharton, R.P.4    Doe, C.Q.5
  • 88
    • 34250888843 scopus 로고    scopus 로고
    • Microtubules tethered at epithelial cell junctions by dynein facilitate efficient junction assembly
    • Ligon, L. A. and Holzbaur, E. L. (2007). Microtubules tethered at epithelial cell junctions by dynein facilitate efficient junction assembly. Traffic 8, 808-819.
    • (2007) Traffic , vol.8 , pp. 808-819
    • Ligon, L.A.1    Holzbaur, E.L.2
  • 89
    • 0034795209 scopus 로고    scopus 로고
    • Dynein binds to betacatenin and may tether microtubules at adherens junctions
    • Ligon, L. A., Karki, S., Tokito, M. and Holzbaur, E. L. (2001). Dynein binds to betacatenin and may tether microtubules at adherens junctions. Nat. Cell Biol. 3, 913-917.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 913-917
    • Ligon, L.A.1    Karki, S.2    Tokito, M.3    Holzbaur, E.L.4
  • 90
    • 0032539868 scopus 로고    scopus 로고
    • Centrosome hypertrophy in human breast tumors: implications for genomic stability and cell polarity
    • Lingle, W. L., Lutz, W. H., Ingle, J. N., Haihle, N. J. and Salisbury, J. L. (1998). Centrosome hypertrophy in human breast tumors: implications for genomic stability and cell polarity. Proc. Natl. Acad. Sci. USA 95, 2950-2955.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 2950-2955
    • Lingle, W.L.1    Lutz, W.H.2    Ingle, J.N.3    Haihle, N.J.4    Salisbury, J.L.5
  • 93
    • 77958485383 scopus 로고    scopus 로고
    • Intestinal stem cell replacement follows a pattern of neutral drift
    • Lopez-Garcia, C., Klein, A. M., Simons, B. D. and Winton, D. J. (2010). Intestinal stem cell replacement follows a pattern of neutral drift. Science 330, 822-825.
    • (2010) Science , vol.330 , pp. 822-825
    • Lopez-Garcia, C.1    Klein, A.M.2    Simons, B.D.3    Winton, D.J.4
  • 94
    • 0035945614 scopus 로고    scopus 로고
    • Adherens junctions inhibit asymmetric division in the Drosophila epithelium
    • Lu, B., Roegiers, F., Jan, L. Y. and Jan, Y. N. (2001). Adherens junctions inhibit asymmetric division in the Drosophila epithelium. Nature 409, 522-525.
    • (2001) Nature , vol.409 , pp. 522-525
    • Lu, B.1    Roegiers, F.2    Jan, L.Y.3    Jan, Y.N.4
  • 96
    • 0030703623 scopus 로고    scopus 로고
    • Apc gene mutation is associated with a dominant-negative effect upon intestinal cell migration
    • Mahmoud, N. N., Boolbol, S. K., Bilinski, R. T., Martucci, C., Chadburn, A. and Bertagnolli, M. M. (1997). Apc gene mutation is associated with a dominant-negative effect upon intestinal cell migration. Cancer Res. 57, 5045-5050.
    • (1997) Cancer Res , vol.57 , pp. 5045-5050
    • Mahmoud, N.N.1    Boolbol, S.K.2    Bilinski, R.T.3    Martucci, C.4    Chadburn, A.5    Bertagnolli, M.M.6
  • 98
    • 0037663344 scopus 로고    scopus 로고
    • Aneuploidy of human testicular germ cell tumors is associated with amplification of centrosomes
    • Mayer, F., Stoop, H., Sen, S., Bokemeyer, C., Oosterhuis, J. W. and Looijenga, L. H. (2003). Aneuploidy of human testicular germ cell tumors is associated with amplification of centrosomes. Oncogene 22, 3859-3866.
    • (2003) Oncogene , vol.22 , pp. 3859-3866
    • Mayer, F.1    Stoop, H.2    Sen, S.3    Bokemeyer, C.4    Oosterhuis, J.W.5    Looijenga, L.H.6
  • 99
    • 77956903803 scopus 로고    scopus 로고
    • Tumor-host interactions: a far-reaching relationship
    • McAllister, S. S. and Weinberg, R. A. (2010). Tumor-host interactions: a far-reaching relationship. J. Clin. Oncol. 28, 4022-4028.
    • (2010) J. Clin. Oncol. , vol.28 , pp. 4022-4028
    • McAllister, S.S.1    Weinberg, R.A.2
  • 100
    • 41549117418 scopus 로고    scopus 로고
    • Cell regulation by the Apc protein: Apc as master regulator of epithelia
    • McCartney, B. M. and Näthke, I. S. (2008). Cell regulation by the Apc protein: Apc as master regulator of epithelia. Curr. Opin. Cell Biol. 20, 186-193.
    • (2008) Curr. Opin. Cell Biol. , vol.20 , pp. 186-193
    • McCartney, B.M.1    Näthke, I.S.2
  • 101
    • 56349123945 scopus 로고    scopus 로고
    • Anchorage of microtubule minus ends to adherens junctions regulates epithelial cell-cell contacts
    • Meng, W., Mushika, Y., Ichii, T. and Takeichi, M. (2008). Anchorage of microtubule minus ends to adherens junctions regulates epithelial cell-cell contacts. Cell 135, 948-959.
    • (2008) Cell , vol.135 , pp. 948-959
    • Meng, W.1    Mushika, Y.2    Ichii, T.3    Takeichi, M.4
  • 102
    • 24944582969 scopus 로고    scopus 로고
    • Interpreting epithelial cancer biology in the context of stem cells: tumor properties and therapeutic implications
    • Miller, S. J., Lavker, R. M. and Sun, T. T. (2005). Interpreting epithelial cancer biology in the context of stem cells: tumor properties and therapeutic implications. Biochim. Biophys. Acta 1756, 25-52.
    • (2005) Biochim. Biophys. Acta , vol.1756 , pp. 25-52
    • Miller, S.J.1    Lavker, R.M.2    Sun, T.T.3
  • 104
    • 33745600820 scopus 로고    scopus 로고
    • Asymmetric and symmetric stem-cell divisions in development and cancer
    • Morrison, S. J. and Kimble, J. (2006). Asymmetric and symmetric stem-cell divisions in development and cancer. Nature 441, 1068-1074.
    • (2006) Nature , vol.441 , pp. 1068-1074
    • Morrison, S.J.1    Kimble, J.2
  • 105
    • 0027930066 scopus 로고
    • The APC gene product associates with microtubules in vivo and promotes their assembly in vitro
    • Munemitsu, S., Souza, B., Muller, O., Albert, I., Bubinfeld, B. and Polakis, P. (1994). The APC gene product associates with microtubules in vivo and promotes their assembly in vitro. Cancer Res. 54, 3676-3681.
    • (1994) Cancer Res , vol.54 , pp. 3676-3681
    • Munemitsu, S.1    Souza, B.2    Muller, O.3    Albert, I.4    Bubinfeld, B.5    Polakis, P.6
  • 106
    • 0742289586 scopus 로고    scopus 로고
    • Microtubule organization and function in epithelial cells
    • Musch, A. (2004). Microtubule organization and function in epithelial cells. Traffic 5, 1-9.
    • (2004) Traffic , vol.5 , pp. 1-9
    • Musch, A.1
  • 107
    • 0035838422 scopus 로고    scopus 로고
    • Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization
    • Nakamura, M., Zhou, X. Z. and Lu, K. P. (2001). Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization. Curr. Biol. 11, 1062-1067.
    • (2001) Curr. Biol. , vol.11 , pp. 1062-1067
    • Nakamura, M.1    Zhou, X.Z.2    Lu, K.P.3
  • 109
    • 23844543408 scopus 로고    scopus 로고
    • Relationship between the role of the adenomatous polyposis coli protein in colon cancer and its contribution to cytoskeletal regulation
    • Nathke, I. S. (2005). Relationship between the role of the adenomatous polyposis coli protein in colon cancer and its contribution to cytoskeletal regulation. Biochem. Soc. Trans. 33, 694-687.
    • (2005) Biochem. Soc. Trans. , vol.33 , pp. 694-687
    • Nathke, I.S.1
  • 110
    • 0025779188 scopus 로고
    • Role of the membranecytoskeleton in the spatial organization of the Na,K-ATPase in polarized epithelial cells
    • Nelson, W. J., Hammerton, R. W. and McNeill, H. (1991). Role of the membranecytoskeleton in the spatial organization of the Na,K-ATPase in polarized epithelial cells. Soc. Gen. Physiol. Ser. 46, 77-87.
    • (1991) Soc. Gen. Physiol. Ser. , vol.46 , pp. 77-87
    • Nelson, W.J.1    Hammerton, R.W.2    McNeill, H.3
  • 111
    • 72549092813 scopus 로고    scopus 로고
    • Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer
    • Neumüller, R. A. and Knoblich, J. A. (2009). Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer. Genes Dev. 23, 2675-2699.
    • (2009) Genes Dev , vol.23 , pp. 2675-2699
    • Neumüller, R.A.1    Knoblich, J.A.2
  • 113
    • 0033230475 scopus 로고    scopus 로고
    • N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression
    • Nieman, M. T., Prudoff, R. S., Johnson, K. R. and Wheelock, M. J. (1999). N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression. J. Cell Biol. 147, 631-644.
    • (1999) J. Cell Biol. , vol.147 , pp. 631-644
    • Nieman, M.T.1    Prudoff, R.S.2    Johnson, K.R.3    Wheelock, M.J.4
  • 114
    • 45249124315 scopus 로고    scopus 로고
    • Role of the VHL (von Hippel-Lindau) gene in renal cancer: a multifunctional tumour suppressor
    • Nyhan, M. J., O'Sullivan, G. C. and McKenna, S. L. (2008). Role of the VHL (von Hippel-Lindau) gene in renal cancer: a multifunctional tumour suppressor. Biochem. Soc. Trans. 36, 472-478.
    • (2008) Biochem. Soc. Trans. , vol.36 , pp. 472-478
    • Nyhan, M.J.1    O'Sullivan, G.C.2    McKenna, S.L.3
  • 115
    • 0034026122 scopus 로고    scopus 로고
    • Mammalian spindle orientation and position respond to changes in cell shape in a dynein-dependent fashion
    • O'Connell, C. B. and Wang, Y. L. (2000). Mammalian spindle orientation and position respond to changes in cell shape in a dynein-dependent fashion. Mol. Biol. Cell 11, 1765-1774.
    • (2000) Mol. Biol. Cell , vol.11 , pp. 1765-1774
    • O'Connell, C.B.1    Wang, Y.L.2
  • 116
    • 33746807862 scopus 로고    scopus 로고
    • Ubiquitin pathway in VHL cancer syndrome
    • Ohh, M. (2006). Ubiquitin pathway in VHL cancer syndrome. Neoplasia 8, 623-629.
    • (2006) Neoplasia , vol.8 , pp. 623-629
    • Ohh, M.1
  • 117
    • 44449111555 scopus 로고    scopus 로고
    • Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways
    • Onder, T. T., Gupta, P. B., Mani, S. A., Yang, J., Lander, E. S. and Weinberg, R. A. (2008). Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Res. 68, 3645-3654.
    • (2008) Cancer Res , vol.68 , pp. 3645-3654
    • Onder, T.T.1    Gupta, P.B.2    Mani, S.A.3    Yang, J.4    Lander, E.S.5    Weinberg, R.A.6
  • 118
    • 0026781163 scopus 로고
    • Role of astral microtubules and actin in spindle orientation and migration in the budding yeast, Saccharomyces cerevisiae
    • Palmer, R. E., Sullivan, D. S., Huffaker, T. and Koshland, D. (1992). Role of astral microtubules and actin in spindle orientation and migration in the budding yeast, Saccharomyces cerevisiae. J. Cell Biol. 119, 583-593.
    • (1992) J. Cell Biol. , vol.119 , pp. 583-593
    • Palmer, R.E.1    Sullivan, D.S.2    Huffaker, T.3    Koshland, D.4
  • 119
    • 44349116202 scopus 로고    scopus 로고
    • Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia
    • Patel, V., Li, L., Cobo-Stark, P., Shao, X., Somlo, S., Lin, F. and Igarashi, P. (2008). Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia. Hum. Mol. Genet. 17, 1578-1590.
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 1578-1590
    • Patel, V.1    Li, L.2    Cobo-Stark, P.3    Shao, X.4    Somlo, S.5    Lin, F.6    Igarashi, P.7
  • 120
    • 0032510494 scopus 로고    scopus 로고
    • A causal role for E-cadherin in the transition from adenoma to carcinoma
    • Perl, A. K., Wilgenbus, P., Dahl, U., Semb, H. and Christofori, G. (1998). A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature 392, 190-193.
    • (1998) Nature , vol.392 , pp. 190-193
    • Perl, A.K.1    Wilgenbus, P.2    Dahl, U.3    Semb, H.4    Christofori, G.5
  • 121
    • 0031769352 scopus 로고    scopus 로고
    • Biogenesis of polarized epithelial cells during kidney development in situ: roles of E-cadherin-mediated cell-cell adhesion and membrane cytoskeleton organization
    • Piepenhagen, P. A. and Nelson, W. J. (1998). Biogenesis of polarized epithelial cells during kidney development in situ: roles of E-cadherin-mediated cell-cell adhesion and membrane cytoskeleton organization. Mol. Biol. Cell 9, 3161-3177.
    • (1998) Mol. Biol. Cell , vol.9 , pp. 3161-3177
    • Piepenhagen, P.A.1    Nelson, W.J.2
  • 122
    • 67649371134 scopus 로고    scopus 로고
    • The APC tumor suppressor is required for epithelial integrity in the mouse mammary gland
    • Prosperi, J. R., Becher, K. R., Willson, T. A., Collins, M. H., Witte, D. P. and Goss, K. H. (2009). The APC tumor suppressor is required for epithelial integrity in the mouse mammary gland. J. Cell Physiol. 220, 319-331.
    • (2009) J. Cell Physiol. , vol.220 , pp. 319-331
    • Prosperi, J.R.1    Becher, K.R.2    Willson, T.A.3    Collins, M.H.4    Witte, D.P.5    Goss, K.H.6
  • 123
    • 77952396762 scopus 로고    scopus 로고
    • Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation
    • Qin, Y., Meisen, W. H., Hao, Y. and Macara, I. G. (2010). Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation. J. Cell Biol. 189, 661-669.
    • (2010) J. Cell Biol. , vol.189 , pp. 661-669
    • Qin, Y.1    Meisen, W.H.2    Hao, Y.3    Macara, I.G.4
  • 125
    • 0030898998 scopus 로고    scopus 로고
    • Cleavage furrow establishment by the moving mitotic apparatus
    • Rappaport, R. (1997). Cleavage furrow establishment by the moving mitotic apparatus. Dev. Growth Differ. 39, 221-226.
    • (1997) Dev. Growth Differ. , vol.39 , pp. 221-226
    • Rappaport, R.1
  • 128
    • 0035141028 scopus 로고    scopus 로고
    • Two types of asymmetric divisions in the Drosophila sensory organ precursor cell lineage
    • Roegiers, F., Younger-Shepherd, S., Jan, L. Y. and Jan, Y. N. (2001). Two types of asymmetric divisions in the Drosophila sensory organ precursor cell lineage. Nat. Cell Biol. 3, 58-67.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 58-67
    • Roegiers, F.1    Younger-Shepherd, S.2    Jan, L.Y.3    Jan, Y.N.4
  • 129
    • 67649939163 scopus 로고    scopus 로고
    • The increasing complexity of the cancer stem cell paradigm
    • Rosen, J. M. and Jordan, C. T. (2009). The increasing complexity of the cancer stem cell paradigm. Science 324, 1670-1673.
    • (2009) Science , vol.324 , pp. 1670-1673
    • Rosen, J.M.1    Jordan, C.T.2
  • 133
    • 0031005659 scopus 로고    scopus 로고
    • The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transition
    • Savagner, P., Yamada, K. M. and Thiery, J. P. (1997). The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transition. J. Cell Biol. 137, 1403-1419.
    • (1997) J. Cell Biol. , vol.137 , pp. 1403-1419
    • Savagner, P.1    Yamada, K.M.2    Thiery, J.P.3
  • 134
    • 0035906940 scopus 로고    scopus 로고
    • Microtubule "plus-end-tracking proteins" : the end is just the beginning
    • Schuyler, S. and Pellman, D. (2001). Microtubule "plus-end-tracking proteins" : the end is just the beginning. Cell 105, 421-424.
    • (2001) Cell , vol.105 , pp. 421-424
    • Schuyler, S.1    Pellman, D.2
  • 135
    • 70449529540 scopus 로고    scopus 로고
    • Cell division orientation and planar cell polarity pathways
    • Segalen, M. and Bellaïche, Y. (2009). Cell division orientation and planar cell polarity pathways. Semin. Cell Dev. Biol. 20, 972-977.
    • (2009) Semin. Cell Dev. Biol. , vol.20 , pp. 972-977
    • Segalen, M.1    Bellaïche, Y.2
  • 136
    • 34548174902 scopus 로고    scopus 로고
    • Adenomatous polyposis coli (APC) plays multiple roles in the intestinal and colorectal epithelia
    • A.S
    • Senda, T., Iizuka-Kogo, A., Onouchi, T. and A. S. (2007). Adenomatous polyposis coli (APC) plays multiple roles in the intestinal and colorectal epithelia. Med. Mol. Morphol. 40, 68-81.
    • (2007) Med. Mol. Morphol. , vol.40 , pp. 68-81
    • Senda, T.1    Iizuka-Kogo, A.2    Onouchi, T.3
  • 137
    • 0036801150 scopus 로고    scopus 로고
    • Asymmetric Numb distribution is critical for asymmetric cell division of mouse cerebral cortical stem cells and neuroblasts
    • Shen, Q., Zhong, W., Jan, Y. N. and Temple, S. (2002). Asymmetric Numb distribution is critical for asymmetric cell division of mouse cerebral cortical stem cells and neuroblasts. Development 129, 4843-4853.
    • (2002) Development , vol.129 , pp. 4843-4853
    • Shen, Q.1    Zhong, W.2    Jan, Y.N.3    Temple, S.4
  • 138
    • 9244249219 scopus 로고    scopus 로고
    • APC and GSK-3beta are involved in mPar3 targeting to the nascent axon and establishment of neuronal polarity
    • Shi, S. H., Cheng, T., Jan, L. Y. and Jan, Y. N. (2004). APC and GSK-3beta are involved in mPar3 targeting to the nascent axon and establishment of neuronal polarity. Curr. Biol. 14, 2025-2032.
    • (2004) Curr. Biol. , vol.14 , pp. 2025-2032
    • Shi, S.H.1    Cheng, T.2    Jan, L.Y.3    Jan, Y.N.4
  • 140
    • 64049088018 scopus 로고    scopus 로고
    • Spindle orientation during asymmetric cell division
    • Siller, K. H. and Doe, C. Q. (2009). Spindle orientation during asymmetric cell division. Nat. Cell Biol. 11, 365-374.
    • (2009) Nat. Cell Biol. , vol.11 , pp. 365-374
    • Siller, K.H.1    Doe, C.Q.2
  • 141
    • 69949165703 scopus 로고    scopus 로고
    • P115 RhoGEF and microtubules decide the direction apoptotic cells extrude from an epithelium
    • Slattum, G., McGee, K. M. and Rosenblatt, J. (2009). P115 RhoGEF and microtubules decide the direction apoptotic cells extrude from an epithelium. J. Cell Biol. 186, 693-702.
    • (2009) J. Cell Biol. , vol.186 , pp. 693-702
    • Slattum, G.1    McGee, K.M.2    Rosenblatt, J.3
  • 142
  • 144
    • 76849110610 scopus 로고    scopus 로고
    • Regulating neural proliferation in the Drosophila CNS
    • Sousa-Nunes, R., Cheng, L. Y. and Gould, A. P. (2010). Regulating neural proliferation in the Drosophila CNS. Curr. Opin. Neurobiol. 20, 50-57.
    • (2010) Curr. Opin. Neurobiol. , vol.20 , pp. 50-57
    • Sousa-Nunes, R.1    Cheng, L.Y.2    Gould, A.P.3
  • 145
    • 63849176160 scopus 로고    scopus 로고
    • Microtubules and cadherins: a neglected partnership
    • Stehbens, S. J., Akhmanova, A. and Yap, A. S. (2009). Microtubules and cadherins: a neglected partnership. Front. Biosci. 14, 3159-3167.
    • (2009) Front. Biosci. , vol.14 , pp. 3159-3167
    • Stehbens, S.J.1    Akhmanova, A.2    Yap, A.S.3
  • 146
    • 0242517286 scopus 로고    scopus 로고
    • Targeting of the myosin-I myr 3 to intercellular adherens type junctions induced by dominant active Cdc42 in HeLa cells
    • Stöffler, H.-E., Honnert, U., Bauer, C. A., Höfer, D., Schwarz, H., Müller, R. T., Drenckhahn, D. and Bähler, M. (1998). Targeting of the myosin-I myr 3 to intercellular adherens type junctions induced by dominant active Cdc42 in HeLa cells. J. Cell Sci. 111, 2779-2788.
    • (1998) J. Cell Sci. , vol.111 , pp. 2779-2788
    • Stöffler, H.-E.1    Honnert, U.2    Bauer, C.A.3    Höfer, D.4    Schwarz, H.5    Müller, R.T.6    Drenckhahn, D.7    Bähler, M.8
  • 147
    • 0036392129 scopus 로고    scopus 로고
    • Epigenetic versus genetic alterations in the inactivation of Ecadherin
    • Strathdee, G. (2002). Epigenetic versus genetic alterations in the inactivation of Ecadherin. Semin. Cancer Biol. 12, 373-379.
    • (2002) Semin. Cancer Biol. , vol.12 , pp. 373-379
    • Strathdee, G.1
  • 148
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery, J. P., Acloque, H., Huang, R. Y. and Nieto, M. A. (2009). Epithelial-mesenchymal transitions in development and disease. Cell 139, 871-890.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 150
    • 1242272912 scopus 로고    scopus 로고
    • The orientation and dynamics of cell division within the plane of the developing vertebrate retina
    • Tibber, M. S., Kralj-Hans, I., Savage, J., Mobbs, P. G. and Jeffery, G. (2004). The orientation and dynamics of cell division within the plane of the developing vertebrate retina. Eur. J. Neurosci. 19, 497-504.
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 497-504
    • Tibber, M.S.1    Kralj-Hans, I.2    Savage, J.3    Mobbs, P.G.4    Jeffery, G.5
  • 151
    • 0033558595 scopus 로고    scopus 로고
    • Polyps as biomarkers for colorectal neoplasia
    • Tobi, M. (1999). Polyps as biomarkers for colorectal neoplasia. Front. Biosci. 4, D329-D338.
    • (1999) Front. Biosci. , vol.4
    • Tobi, M.1
  • 152
    • 33947596005 scopus 로고    scopus 로고
    • Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1-and myosin X-dependent manner
    • Toyoshima, F. and Nishida, E. (2007a). Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1-and myosin X-dependent manner. EMBO J. 26, 1487-1498.
    • (2007) EMBO J , vol.26 , pp. 1487-1498
    • Toyoshima, F.1    Nishida, E.2
  • 153
    • 34848840325 scopus 로고    scopus 로고
    • Spindle orientation in animal cell mitosis: roles of integrin in the control of spindle axis
    • Toyoshima, F. and Nishida, E. (2007b). Spindle orientation in animal cell mitosis: roles of integrin in the control of spindle axis. J. Cell. Physiol. 213, 407-411.
    • (2007) J. Cell. Physiol. , vol.213 , pp. 407-411
    • Toyoshima, F.1    Nishida, E.2
  • 155
    • 0033533731 scopus 로고    scopus 로고
    • Absence of Brca2 causes genome instability by chromosome breakage and loss associated with centrosome amplification
    • Tutt, A., Gabriel, A., Bertwistle, D., Connor, F., Paterson, H., Peacock, J., Ross, G. and Ashworth, A. (1999). Absence of Brca2 causes genome instability by chromosome breakage and loss associated with centrosome amplification. Curr. Biol. 9, 1107-1110.
    • (1999) Curr. Biol. , vol.9 , pp. 1107-1110
    • Tutt, A.1    Gabriel, A.2    Bertwistle, D.3    Connor, F.4    Paterson, H.5    Peacock, J.6    Ross, G.7    Ashworth, A.8
  • 156
    • 0035312694 scopus 로고    scopus 로고
    • LIS1: cellular function of a diseasecausing gene
    • Vallee, R. B., Tai, C. and Faulkner, N. E. (2001). LIS1: cellular function of a diseasecausing gene. Trends Cell Biol. 11, 155-160.
    • (2001) Trends Cell Biol , vol.11 , pp. 155-160
    • Vallee, R.B.1    Tai, C.2    Faulkner, N.E.3
  • 157
    • 4344572283 scopus 로고    scopus 로고
    • Rho overexpression leads to mitosis-associated detachment of cells from epithelial sheets: a link to the mechanism of cancer dissemination
    • Vasiliev, J. M., Omelchenko, T., Gelfand, I. M., Feder, H. H. and Bonder, E. M. (2004). Rho overexpression leads to mitosis-associated detachment of cells from epithelial sheets: a link to the mechanism of cancer dissemination. Proc. Natl. Acad. Sci. USA 101, 12526-12530.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 12526-12530
    • Vasiliev, J.M.1    Omelchenko, T.2    Gelfand, I.M.3    Feder, H.H.4    Bonder, E.M.5
  • 158
    • 0023198134 scopus 로고
    • Formation of the apical pole of epithelial (Madin-Darby canine kidney) cells: polarity of an apical protein is independent of tight junctions while segregation of a basolateral marker requires cell-cell interactions
    • Vega-Salas, D. E., Salas, P. J., Gundersen, D. and Rodriguez-Boulan, E. (1987). Formation of the apical pole of epithelial (Madin-Darby canine kidney) cells: polarity of an apical protein is independent of tight junctions while segregation of a basolateral marker requires cell-cell interactions. J. Cell Biol. 104, 905-916.
    • (1987) J. Cell Biol. , vol.104 , pp. 905-916
    • Vega-Salas, D.E.1    Salas, P.J.2    Gundersen, D.3    Rodriguez-Boulan, E.4
  • 159
    • 0025818032 scopus 로고
    • Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role
    • Vleminckx, K., Vakaet, L. J., Mareel, M., Fiers, W. and van Roy, F. (1991). Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 66, 107-119.
    • (1991) Cell , vol.66 , pp. 107-119
    • Vleminckx, K.1    Vakaet, L.J.2    Mareel, M.3    Fiers, W.4    van Roy, F.5
  • 161
    • 62849126658 scopus 로고    scopus 로고
    • The expression of E-cadherin at the invasive tumor front of oral squamous cell carcinoma: immunohistochemical and RT-PCR analysis with clinicopathological correlation
    • Wang, X., Zhang, J., Fan, M., Zhou, Q., Deng, H., Aisharif, M. J. and Chen, X. (2009). The expression of E-cadherin at the invasive tumor front of oral squamous cell carcinoma: immunohistochemical and RT-PCR analysis with clinicopathological correlation. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 107, 547-554.
    • (2009) Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. , vol.107 , pp. 547-554
    • Wang, X.1    Zhang, J.2    Fan, M.3    Zhou, Q.4    Deng, H.5    Aisharif, M.J.6    Chen, X.7
  • 163
    • 33750626189 scopus 로고    scopus 로고
    • Does aneuploidy cause cancer? Curr
    • Weaver, B. A. and Cleveland, D. W. (2006). Does aneuploidy cause cancer? Curr. Opin. Cell Biol. 18, 658-667.
    • (2006) Opin. Cell Biol. , vol.18 , pp. 658-667
    • Weaver, B.A.1    Cleveland, D.W.2
  • 165
    • 24644499168 scopus 로고    scopus 로고
    • Molecular control of cell polarity and asymmetric cell division in Drosophila neuroblasts
    • Wodarz, A. (2005). Molecular control of cell polarity and asymmetric cell division in Drosophila neuroblasts. Curr. Opin. Cell Biol. 17, 475-481.
    • (2005) Curr. Opin. Cell Biol. , vol.17 , pp. 475-481
    • Wodarz, A.1
  • 166
    • 0026551855 scopus 로고
    • Remodeling the cell surface distribution of membrane proteins during the development of epithelial cell polarity
    • Wollner, D. A. and Krzeminski, K. A. (1992). Remodeling the cell surface distribution of membrane proteins during the development of epithelial cell polarity. J. Cell Biol. 116, 889-899.
    • (1992) J. Cell Biol. , vol.116 , pp. 889-899
    • Wollner, D.A.1    Krzeminski, K.A.2
  • 167
    • 0029835278 scopus 로고    scopus 로고
    • Forced expression of the tumor suppressor adenomatous polyposis coli protein induces disordered cell migration in the intestinal epithelium
    • Wong, M., Hermiston, M. L., Syder, A. J. and Gordon, J. I. (1996). Forced expression of the tumor suppressor adenomatous polyposis coli protein induces disordered cell migration in the intestinal epithelium. Proc. Natl. Acad. Sci. USA 93, 9588-9593.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9588-9593
    • Wong, M.1    Hermiston, M.L.2    Syder, A.J.3    Gordon, J.I.4
  • 168
    • 0344392858 scopus 로고    scopus 로고
    • Mutations in a beta-tubulin disrupt spindle orientation and microtubule dynamics in the early Caenorhabditis elegans embryo
    • Wright, A. J. and Hunter, C. P. (2003). Mutations in a beta-tubulin disrupt spindle orientation and microtubule dynamics in the early Caenorhabditis elegans embryo. Mol. Biol. Cell 14, 4512-4525.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 4512-4525
    • Wright, A.J.1    Hunter, C.P.2
  • 169
    • 77954919005 scopus 로고    scopus 로고
    • Epicardial spindle orientation controls cell entry into the myocardium
    • Wu, M., Smith, C. L., Hall, J. A., Lee, I., Luby-Phelps, K. and Tallquist, M. D. (2010). Epicardial spindle orientation controls cell entry into the myocardium. Dev. Cell 19, 114-125.
    • (2010) Dev. Cell , vol.19 , pp. 114-125
    • Wu, M.1    Smith, C.L.2    Hall, J.A.3    Lee, I.4    Luby-Phelps, K.5    Tallquist, M.D.6
  • 170
    • 44949183595 scopus 로고    scopus 로고
    • Molecular and cell biology of brain tumor stem cells: lessons from neural progenitor/stem cells
    • Xie, Z. and Chin, L. S. (2008). Molecular and cell biology of brain tumor stem cells: lessons from neural progenitor/stem cells. Neurosurg. Focus 24, E25.
    • (2008) Neurosurg. Focus , vol.24
    • Xie, Z.1    Chin, L.S.2
  • 171
    • 63849244921 scopus 로고    scopus 로고
    • Regulation of asymmetric stem cell division: spindle orientation and the centrosome
    • Yamashita, Y. M. (2009). Regulation of asymmetric stem cell division: spindle orientation and the centrosome. Front. Biosci. 14, 3003-3011.
    • (2009) Front. Biosci. , vol.14 , pp. 3003-3011
    • Yamashita, Y.M.1
  • 172
    • 0141483737 scopus 로고    scopus 로고
    • Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome
    • Yamashita, Y. M., Jones, D. L. and Fuller, M. T. (2003). Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome. Science 301, 1547-1550.
    • (2003) Science , vol.301 , pp. 1547-1550
    • Yamashita, Y.M.1    Jones, D.L.2    Fuller, M.T.3
  • 175
    • 0037328574 scopus 로고    scopus 로고
    • Hepatocyte growth factor switches orientation of polarity and mode of movement during morphogenesis of multicellular epithelial structures
    • Yu, W., O'Brien, L. E., Wang, F., Bourne, H., Mostov, K. E. and Zegers, M. M. (2003). Hepatocyte growth factor switches orientation of polarity and mode of movement during morphogenesis of multicellular epithelial structures. Mol. Biol. Cell 14, 748-763.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 748-763
    • Yu, W.1    O'Brien, L.E.2    Wang, F.3    Bourne, H.4    Mostov, K.E.5    Zegers, M.M.6
  • 176
    • 77951174042 scopus 로고    scopus 로고
    • LGN regulates mitotic spindle orientation during epithelial morphogenesis
    • Zheng, Z., Zhu, H., Wan, Q., Liu, J., Xiao, Z., Siderovski, D. P. and Du, Q. (2010). LGN regulates mitotic spindle orientation during epithelial morphogenesis. J. Cell Biol. 189, 275-288.
    • (2010) J. Cell Biol. , vol.189 , pp. 275-288
    • Zheng, Z.1    Zhu, H.2    Wan, Q.3    Liu, J.4    Xiao, Z.5    Siderovski, D.P.6    Du, Q.7
  • 177
    • 0035176077 scopus 로고    scopus 로고
    • Binding of the Adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation
    • Zumbrunn, J., Kinoshita, K., Hyman, A. A. and Nathke, I. S. (2001). Binding of the Adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation. Curr. Biol. 11, 44-49.
    • (2001) Curr. Biol. , vol.11 , pp. 44-49
    • Zumbrunn, J.1    Kinoshita, K.2    Hyman, A.A.3    Nathke, I.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.