Spindle orientation in animal cell mitosis: Roles of integrin in the control of spindle axis

Journal of Cellular Physiology

Volumn 213, Issue 2, 2007, Pages 407-411

  Toyoshima, Fumiko ^a,b   Nishida, Eisuke ^a  

^a KYOTO UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; BINDING PROTEIN; INTEGRIN; TUMOR SUPPRESSOR PROTEIN;

CELL ADHESION; CELL CULTURE; CELL DIVISION; CELL JUNCTION; CELL POLARITY; EPITHELIUM CELL; EXTRACELLULAR MATRIX; GRAVITY; HUMAN; MICROTUBULE; MITOSIS; MITOSIS SPINDLE; MOLECULAR INTERACTION; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SHORT SURVEY;

ANIMALS; CELL POLARITY; CELLS, CULTURED; EXTRACELLULAR MATRIX; INTEGRINS; MITOSIS; MITOTIC SPINDLE APPARATUS;

ANIMALIA;

EID: 34848840325     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21227     Document Type: Short Survey

References (73)

1. Baena-Lopez LA, Baonxa A, Garcia-Bellido A. 2005. The orientation of cell divisions determines the shape of Drosophila organs. Curr Biol 15:1640-1644.
2. Bellaiche Y, Gotta M. 2005. Heterotrimeric G proteins and regulation of size asymmetry during cell division. Curr Opin Cell Biol 17:658-663.
3. Berdnik D, Knoblich JA. 2002. Drosophila aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis. Curr Biol 12:640-647.
4. Betschinger J, Knoblich JA. 2004. Dare to be different: Asymmetric cell division in Drosophila, C. elegans and vertebrates. Curr Biol 14:R674-685.
5. Bowman SK, Neumuller RA, Novatchkova M, Du Q, Knoblich JA. 2006. The Drosophila NuMA Homolog Mud regulates spindle orientation in asymmetric cell division. Dev Cell 10:731-742.
6. Colombo K, Grill SW, Kimple RJ, Willard FS, Siderovski DP, Gonczy P. 2003. Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos. Science 300:1957-1961.
7. Compton DA, Szilak I, Cleveland DW. 1992. Primary structure of NuMA, an intranuclear protein that defines a novel pathway for segregation of proteins at mitosis. J Cell Biol 116:1395-1408.
8. Cowan CR, Hyman AA. 2004. Asymmetric cell division in C. elegans: Cortical polarity and spindle positioning. Annu Rev Cell Dev Biol 20:427-453.
9. Doe CQ, Bowerman B. 2001. Asymmetric cell division: Fly neuroblast meets worm zygote. Curr Opin Cell Biol 13:68-75.
10. Draviam VM, Shapiro I, Aldridge B, Sorger PK. 2006. Misorientation and reduced stretching of aligned sister kinetochores promote chromosome m is segregation in EB1- or APC-depleted cells. EMBO J 25:2814-2827.
11. Du Q, Macara IG. 2004. Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins. Cell 119:503-516.
12. Du Q, Stukenberg PT, Macara IG. 2001. A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization. Nat Cell Biol 3:1069-1075.
13. Du Q, Taylor L, Compton DA, Macara IG. 2002. LGN blocks the ability of NuMA to bind and stabilize microtubules. A mechanism for mitotic spindle assembly regulation. Curr Biol 12:1928-1933.
14. Feng Y, Walsh CA. 2004. Mitotic spindle regulation by Nde 1 controls cerebral cortical size. Neuron 44:279-293.
15. Fernandez-Minan A, Martin-Bermudo MD, Gonzalez-Reyes A. 2007. Integrin signaling regulates spindle orientation in Drosophila to preserve the follicular-epithelium monolayer. Curr Biol 17:683-688.
16. Fischer E, Legue E, Doyen A, Nato F, Nicolas JF, Torres V, Yaniv M, Pontoglio M. 2006. Defective planar cell polarity in polycystic kidney disease. Nat Genet 38:21-23.
17. Gaglio T, Saredi A, Compton DA. 1995. NuMA is required for the organization of microtubules into aster-like mitotic arrays. J Cell Biol 131:693-708.
18. Geldmacher-Voss B, Reugels AM, Pauls S, Campos-Ortega JA. 2003. A 90-degree rotation of the mitotic spindle changes the orientation of mitoses of zebrafish neuroepithelial cells. Development 130:3767-3780.
19. Gho M, Schweisguth F. 1998. Frizzled signalling controls orientation of asymmetric sense organ precursor cell divisions in Drosophila. Nature 393:178-181.
20. Gonczy P. 2002. Mechanisms of spindle positioning: Focus on flies and worms. Trends Cell Biol 12:332-339.
21. Gong Y, Mo C, Fraser SE. 2004. Planar cell polarity signalling controls cell division orientation during zebrafish gastrulation. Nature 430:689-693.
22. Gonzalez C. 2007. Spindle orientation, asymmetric division, and tumour suppression in Drosophila stem cells. Nat Rev Genet 8:462-472.
23. Gordon MB, Howard L, Compton DA. 2001. Chromosome movement in mitosis requires microtubule anchorage at spindle poles. J Cell Biol 152:425-434.
24. Gotta M, Ahringer J. 2001. Distinct roles for Galpha and Gbetagamma in regulating spindle position and orientation in Caenorhabditis elegans embryos. Nat Cell Biol 3:297-300.
25. Gotta M, Dong Y, Peterson YK, Lanier SM, Ahringer J. 2003. Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo. Curr Biol 13:1029-1037
26. Green RA, Kaplan KB. 2003. Chromosome instability in colorectal tumor cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC. J Cell Biol 163:949-961.
27. Green RA, Wollman R, Kaplan KB. 2005. APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment. Mol Biol Cell 16:4609-4622.
28. Gundersen GG, Bretscher A. 2003. Microtubule asymmetry. Science 300:2040-2041.
29. Gundersen GG, Gomes ER, Wen Y. 2004. Cortical control of microtubule stability and polarization. Curr Opin Cell Biol 16:106-112.
30. Haren L, Merdes A. 2002. Direct binding of NuMA to tubulin is mediated by a novel sequence motif in the tail domain that bundles and stabilizes microtubules. J Cell Sci 115:1815-1824.
31. Izumi Y, Ohta N, Hisata K, Raabe T, Matsuzaki F. 2006. Drosophila Pins-binding protein Mud regulates spindle-polarity coupling and centrosome organization. Nat Cell Biol 8:586-593.
32. Jan YN, Jan LY. 2001. Asymmetric cell division in the Drosophila nervous system. Nat Rev Neurosci 2:772-779.
33. Lamprecht J. 1990. Symmetric and asymmetric cell division in rat corneal epithelium. Cell Tissue Kinet 23:203-216.
34. Le Borgne R, Bellaiche Y, Schweisguth F. 2002. Drosophila E-cadherin regulates the orientation of asymmetric cell division in the sensory organ lineage. Curr Biol 12:95-104.
35. Lechler T, Fuchs E. 2005. Asymmetric cell divisions promote stratification and differentiation of mammalian skin. Nature 437:275-280.
36. Lee CY, Anderson RO, Cabernard C, Manning L, Tran KD, Lanskey MJ, Bashirullah A, Doe CQ. 2006. Drosophila aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation. Genes Dev 20:3464-3474.
37. Li N, Zhang Y, Naylor MJ, Schatzmann F, Maurer F, Wintermantel T, Schuetz G, Mueller U, Streuli CH, Hynes NE. 2005. Beta 1 integrins regulate mammary gland proliferation and maintain the integrity of mammary alveoli. EMBO J 24:1942-1953.
38. Lu B, Roegiers F, Jan LY, Jan YN. 2001. Adherens junctions inhibit asymmetric division in the Drosophila epithelium. Nature 409:522-525.
39. Machesky LM, Hall A. 1997. Role of actin polymerization and adhesion to extracellular matrix in Rac- and Rho-induced cytoskeletal reorganization. J Cell Biol 138:913-926.
40. Matsuzaki F. 2000. Asymmetric division of Drosophila neural stem cells: A basis for neural diversity. Curr Opin Neurobiol 10:38-44.
41. McCarthy EK, Goldstein B. 2006. Asymmetric spindle positioning. Curr Opin Cell Biol 18:79-85.
42. Merdes A, Ramyar K, Vechio JD, Cleveland DW. 1996. A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly. Cell 87:447-458.
43. Mimori-Kiyosue Y, Tsukita S. 2003. "Search-and-capture" of microtubules through plus-end-binding proteins (+TIPs). J Biochem 134:321-326.
44. Naylor MJ, Li N, Cheung J, Lowe ET, Lambert E, Marlow R, Wang P, Schatzmann F, Wintermantel T, Schuetz G, Clarke AR, Mueller U, Hynes NE, Streuli CH. 2005. Ablation of beta1 integrin in mammary epithelium reveals a key role for integrin in glandular morphogenesis and differentiation. J Cell Biol 171:717-728.
45. O'Connell CB, Wang YL. 2000. Mammalian spindle orientation and position respond to changes in cell shape in a dynein-dependent fashion. Mol Biol Cell 11:1765-1774.
46. Pearson CG, Bloom K. 2004. Dynamic microtubules lead the way for spindle positioning. Naure Rev Mol Cell Biol 5:481-492.
47. Pierschbacher MD, Ruoslahti E. 1984. Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule. Nature 309:30-33.
48. Pugacheva EN, Golemis EA. 2005. The focal adhesion scaffolding protein HEF1 regulates activation ofthe Aurora-A and Nek2 kinases at the centrosome. Nat Cell Biol 7:937-946.
49. Reinsch S, Karsenti E. 1994. Orientation of spindle axis and distribution of plasma membrane proteins during cell division in polarized MDCKII cells. J Cell Biol 126:1509-1526.
50. Reverte CG, Benware A, Jones CW, LaFlamme SE. 2006. Perturbing integrin function inhibits microtubule growth from centrosomes, spindle assembly, and cytokinesis. J Cell Biol 174:491-497.
51. Rogers SL, Rogers GC, Sharp DJ, Vale RD. 2002. Drosophila EBI is important for proper assembly, dynamics, and positioning ofthe mitotic spindle. J Cell Biol 158:873-884.
52. Sanada K, Tsai LH. 2005. G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitors. Cell 122:119-131.
53. Schaefer M, Petronczki M, Dorner D, Forte M, Knoblich JA. 2001. Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system. Cell 107:183-194.
54. Schneider SQ, Bowerman B. 2003. Cell polarity and the cytoskeleton in the Caenorhabditis elegans zygote. Annu Rev Genet 37:221-249.
55. Schuyler SC, Pellman D. 2001. Microtubule "plus-end-tracking proteins": The end is just the beginning. Cell 105:421-424.
56. Siller KH, Cabernard C, Doe CQ. 2006. The NuMA-related Mud protein binds Pins and regulates spindle orientation in Drosophila neuroblasts. Nat Cell Biol 8:594-600.
57. Srinivasan DG, Fisk RM, Xu H, van den Heuvel S. 2003. A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function in C. elegans. Genes Dev 17:1225-1239.
58. Tawk M, Araya C, Lyons DA, Reugels AM, Girdler GC, Bayley PR, Hyde DR, Tada M, Clarke JD. 2007. A mirror-symmetric cell division that orchestrates neuroepithelial morphogenesis. Nature 446:797-800.
59. Thery M, Bornens M. 2006. Cell shape and cell division. Curr Opin Cell Biol 18:648-657.
60. Thery M, Racine V, Pepin A, Piel M, Chen Y, Sibarita JB, Bornens M. 2005. The extracellular matrix guides the orientation of the cell division axis. Nat Cell Biol 7:947-953.
61. Thery M, Jimenez-Dalmaroni A, Racine V, Bornens M, Julicher F. 2007. Experimental and theoretical study of mitotic spindle orientation. Nature 447:493-496.
62. Toyoshima F, Nishida E. 2007. Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1 - and myosin X-dependent manner. EMBO J 26:1487-1498.
63. Weber KL, Sokac AM, Berg JS, Cheney RE, Bernent WMA. 2004. Microtubule-binding myosin required for nuclear anchoring and spindle assembly. Nature 431:325-329.
64. Wilkie TM, Kinch L. 2005. New roles for Galpha and RGS proteins: Communication continues despite pulling sisters apart. Curr Biol 15:R843-854.
65. Wilson EB. 1925. The Cell in Development and Heredity, 3rd edition. New York: The Macmillian Company.
66. Wodarz A. 2005. Molecular control of cell polarity and asymmetric cell division in Drosophila neuroblasts. Curr Opin Cell Biol 17:475-481.
67. Wodarz A, Huttner WB. 2003. Asymmetric cell division during neurogenesis in Drosophila and vertebrates. Mech Dev 120:1297-1309.
68. Yamada KM, Kennedy DW. 1984. Dualistic nature of adhesive protein function: Fibronectin and its biologically active peptide fragments can autoinhibit fibronectin function. J Cell Biol 99:29-36.
69. Yamashita YM, Jones DL, Fuller MT. 2003. Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome. Science 301:1547-1550.
70. Yu F, Wang H, Qian H, Kaushik R, Bownes M, Yang X, Chia W. 2005. Locomotion defects, together with Pins, regulates heterotrimeric G-protein signaling during Drosophila neuroblast asymmetric divisions. Genes Dev 19:1341-1353.
71. Yu F, Kuo CT, Jan YN. 2006. Drosophila neuroblast asymmetric cell division: Recent advances and implications for stem cell biology. Neuron 51:13-20.
72. Zhang H, Berg JS, Li Z, Wang Y, Lang P, Sousa AD, Bhaskar A, Cheney RE, Stromblad S. 2004. Myosin-X provides a motor-based link between integrins and the cytoskeleton. Nature Cell Biol 6:523-531.
73. Zhao ZS, Lim JP, Ng YW, Lim L, Manser E. 2005. The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A. Mol Cell 20:237-249.