-
1
-
-
0024453308
-
Identification of the cystic fibrosis gene: Chromosome walking and jumping
-
Rommens, J.M.; Iannuzzi, M.C.; Kerem, B.; Drumm, M.L. and Melmer, G. (1989) Identification of the cystic fibrosis gene: chromosome walking and jumping. Science, 245, 1059-1065.
-
(1989)
Science
, vol.245
, pp. 1059-1065
-
-
Rommens, J.M.1
Iannuzzi, M.C.2
Kerem, B.3
Drumm, M.L.4
Melmer, G.5
-
2
-
-
0024424270
-
Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
-
[Erratum, Science, 1989, 245, 1437]
-
Riordan, J.R.; Rommens, J.M.; Kerem, B.; Alon, N.; Rozmahel, R.; Grzelczak, Z.; Zielenski, J.; Lok, S.; Plavsic, N.; Chou, J.L.; Drumm, M.L.; Iannuzzi, M.C.; Collins, F.S. and Tsui, L.-C. (1989) Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science, 245, 1066-1073 [Erratum, Science, 1989, 245, 1437].
-
(1989)
Science
, vol.245
, pp. 1066-1073
-
-
Riordan, J.R.1
Rommens, J.M.2
Kerem, B.3
Alon, N.4
Rozmahel, R.5
Grzelczak, Z.6
Zielenski, J.7
Lok, S.8
Plavsic, N.9
Chou, J.L.10
Drumm, M.L.11
Iannuzzi, M.C.12
Collins, F.S.13
Tsui, L.-C.14
-
3
-
-
0024423668
-
Identification of the cystic fibrosis gene: Genetic analysis
-
Kerem, B.; Rommens, J.M.; Buchanan, J.A.; Markiewicz, D.; Cox, T.K.; Chakravarti, A.; Buchwald, M. and Tsui, L.C. (1989) Identification of the cystic fibrosis gene: genetic analysis. Science, 245, 1073-1080.
-
(1989)
Science
, vol.245
, pp. 1073-1080
-
-
Kerem, B.1
Rommens, J.M.2
Buchanan, J.A.3
Markiewicz, D.4
Cox, T.K.5
Chakravarti, A.6
Buchwald, M.7
Tsui, L.C.8
-
4
-
-
0022970788
-
Missing Cl conductance in cystic fibrosis
-
Quinton, P.M. (1986) Missing Cl conductance in cystic fibrosis. Am. J. Physiol., 251, C649-C652.
-
(1986)
Am. J. Physiol.
, vol.251
-
-
Quinton, P.M.1
-
5
-
-
0032913809
-
Physiological basis of cystic fibrosis: A historical perspective
-
Quinton, P.M. (1999) Physiological basis of cystic fibrosis: a historical perspective. Physiol. Rev., 79, S3-S22.
-
(1999)
Physiol. Rev.
, vol.79
-
-
Quinton, P.M.1
-
6
-
-
0346505482
-
New concepts of the pathogenesis of cystic fibrosis lung disease
-
Boucher, R.C. (2004) New concepts of the pathogenesis of cystic fibrosis lung disease. Eur. Respir. J., 23, 146-158.
-
(2004)
Eur. Respir. J.
, vol.23
, pp. 146-158
-
-
Boucher, R.C.1
-
7
-
-
18344395560
-
Cystic fibrosis
-
Rowe, S.M.; Miller, S. and Sorscher, E.J. (2005) Cystic fibrosis. N. Engl. J. Med., 352, 1992-2001.
-
(2005)
N. Engl. J. Med.
, vol.352
, pp. 1992-2001
-
-
Rowe, S.M.1
Miller, S.2
Sorscher, E.J.3
-
8
-
-
0032424454
-
Severe viral respiratory infections in infants with cystic fibrosis
-
Armstrong, D.; Grimwood, K.; Carlin, J.B.; Carzino, R.; Hull, J.; Olinsky, A. and Phelan, P.D. (1998) Severe viral respiratory infections in infants with cystic fibrosis. Pediatr. Pulmonol., 26, 371-379.
-
(1998)
Pediatr. Pulmonol.
, vol.26
, pp. 371-379
-
-
Armstrong, D.1
Grimwood, K.2
Carlin, J.B.3
Carzino, R.4
Hull, J.5
Olinsky, A.6
Phelan, P.D.7
-
9
-
-
0035947372
-
Impairment of the ubiquitin-proteasome system by protein aggregation
-
Bence, N.F.; Sampat, R.M. and Kopito, R.R. (2001) Impairment of the ubiquitin-proteasome system by protein aggregation. Science, 292, 1552-1555.
-
(2001)
Science
, vol.292
, pp. 1552-1555
-
-
Bence, N.F.1
Sampat, R.M.2
Kopito, R.R.3
-
10
-
-
65649115086
-
Mechanisms of the noxious inflammatory cycle in cystic fibrosis
-
Rottner, M.; Freyssinet, J.M. and Martinez, M.C. (2009) Mechanisms of the noxious inflammatory cycle in cystic fibrosis. Respir. Res., 10, 23.
-
(2009)
Respir. Res.
, vol.10
, pp. 23
-
-
Rottner, M.1
Freyssinet, J.M.2
Martinez, M.C.3
-
12
-
-
0032433707
-
Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airway disease
-
Matsui, H.; Grubb, B.R.; Tarran, R.; Randell, S.H.; Gatzy, J.T.; Davis, C.W. and Boucher, R.C. (1998) Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airway disease. Cell, 95, 1005-1015.
-
(1998)
Cell
, vol.95
, pp. 1005-1015
-
-
Matsui, H.1
Grubb, B.R.2
Tarran, R.3
Randell, S.H.4
Gatzy, J.T.5
Davis, C.W.6
Boucher, R.C.7
-
13
-
-
0036167851
-
Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients
-
Worlitzsch, D.; Tarran, R.; Ulrich, M.; Schwab, U.; Cekici, A.; Meyer, K.C.; Birrer, P.; Bellon, G.; Berger, J.; Weiss, A.; Botzenhart, K.; Yankaskas, J.R.; Randell, S.; Boucher, R.C. and Doring, G. (2002) Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients. J. Clin. Invest., 109, 317-325.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 317-325
-
-
Worlitzsch, D.1
Tarran, R.2
Ulrich, M.3
Schwab, U.4
Cekici, A.5
Meyer, K.C.6
Birrer, P.7
Bellon, G.8
Berger, J.9
Weiss, A.10
Botzenhart, K.11
Yankaskas, J.R.12
Randell, S.13
Boucher, R.C.14
Doring, G.15
-
14
-
-
0002414405
-
Microbiology of cystic fibrosis
-
Hodson, M. E.; Geddes, D. M., Eds. Chapman & Hall: London
-
Hoiby, N. Microbiology of cystic fibrosis. In Cystic fibrosis, Hodson, M. E.; Geddes, D. M., Eds. Chapman & Hall: London, 1995, pp. 75-98.
-
(1995)
Cystic Fibrosis
, pp. 75-98
-
-
Hoiby, N.1
-
15
-
-
33845309114
-
A physical linkage between cystic fibrosis airway surface dehydration and Pseudomonas aeruginosa biofilms
-
Matsui, H.; Wagner, V.E.; Hill, D.B.; Schwab, U.E.; Rogers, T.D.; Button, B.; Taylor, R.M.N.; Superfine, R.; Rubinstein, M.; Iglewski, B.H. and Boucher, R.C. (2006) A physical linkage between cystic fibrosis airway surface dehydration and Pseudomonas aeruginosa biofilms. Proc. Natl. Acad. Sci. USA, 103, 18131-18136.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 18131-18136
-
-
Matsui, H.1
Wagner, V.E.2
Hill, D.B.3
Schwab, U.E.4
Rogers, T.D.5
Button, B.6
Taylor, R.M.N.7
Superfine, R.8
Rubinstein, M.9
Iglewski, B.H.10
Boucher, R.C.11
-
16
-
-
23244461620
-
Reduced three-dimensional motility in dehydrated airway mucus prevents neutrophil capture and killing bacteria on airway epithelial surfaces
-
Matsui, H.; Verghese, M.W.; Kesimer, M.; Schwab, U.E.; Randell, S.H.; Sheehan, J.K.; Grubb, B.R. and Boucher, R.C. (2005) Reduced three-dimensional motility in dehydrated airway mucus prevents neutrophil capture and killing bacteria on airway epithelial surfaces. J. Immunol., 175, 1090-1099.
-
(2005)
J. Immunol.
, vol.175
, pp. 1090-1099
-
-
Matsui, H.1
Verghese, M.W.2
Kesimer, M.3
Schwab, U.E.4
Randell, S.H.5
Sheehan, J.K.6
Grubb, B.R.7
Boucher, R.C.8
-
17
-
-
4544353992
-
Submucosal glands and airway defense
-
Wine, J.J. and Joo, N.S. (2004) Submucosal glands and airway defense. Proc. Am. Thorac. Soc., 1, 47-53.
-
(2004)
Proc. Am. Thorac. Soc.
, vol.1
, pp. 47-53
-
-
Wine, J.J.1
Joo, N.S.2
-
18
-
-
0029823833
-
Cystic Fibrosis
-
Davis, P.B.; Drumm, M. and Konstan, M.W. (1996) Cystic Fibrosis. Am. J. Respir. Crit. Care Med., 154, 1229-1256.
-
(1996)
Am. J. Respir. Crit. Care Med.
, vol.154
, pp. 1229-1256
-
-
Davis, P.B.1
Drumm, M.2
Konstan, M.W.3
-
19
-
-
0028914085
-
Early pulmonary inflammation in infants with cystic fibrosis
-
Khan, T.Z.; Wagener, J.S.; Bost, T.; Martinez, J.; Accurso, F.J. and Riches, D.W.H. (1995) Early pulmonary inflammation in infants with cystic fibrosis. Am. J. Respir. Crit. Care Med., 151, 1075-1082.
-
(1995)
Am. J. Respir. Crit. Care Med.
, vol.151
, pp. 1075-1082
-
-
Khan, T.Z.1
Wagener, J.S.2
Bost, T.3
Martinez, J.4
Accurso, F.J.5
Riches, D.W.H.6
-
20
-
-
13444312010
-
Role of IL-10 deficiency in excessive nuclear factor-kappaB activation and lung inflammation in cystic fibrosis transmembrane conductance regulator knockout mice
-
Saadane, A.; Soltys, J. and Berger, M. (2005) Role of IL-10 deficiency in excessive nuclear factor-kappaB activation and lung inflammation in cystic fibrosis transmembrane conductance regulator knockout mice. J. Allergy Clin. Immunol., 115, 405-411.
-
(2005)
J. Allergy Clin. Immunol.
, vol.115
, pp. 405-411
-
-
Saadane, A.1
Soltys, J.2
Berger, M.3
-
21
-
-
0033844485
-
Inflammation and infection in naive human cystic fibrosis airway xenografts
-
Tirouvanziam, R.; de Bentzmann, S.; Hubeau, C.; Hinnrasky, J.; Jacquot, J.; Péault, B. and Puchelle, E. (2000) Inflammation and infection in naive human cystic fibrosis airway xenografts. Am. J. Respir. Cell Mol. Biol., 23, 121-127.
-
(2000)
Am. J. Respir. Cell Mol. Biol.
, vol.23
, pp. 121-127
-
-
Tirouvanziam, R.1
de Bentzmann, S.2
Hubeau, C.3
Hinnrasky, J.4
Jacquot, J.5
Péault, B.6
Puchelle, E.7
-
22
-
-
0034816052
-
Activation of NF-kappaB in airway epithelial cells is dependent on CFTR trafficking and Cl- channel function
-
Weber, A.J.; Soong, G.; Bryan, R.; Saba, S. and Prince, A. (2001) Activation of NF-kappaB in airway epithelial cells is dependent on CFTR trafficking and Cl- channel function. Am. J. Physiol. Lung Cell. Mol. Physiol., 281, L71-L78.
-
(2001)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.281
-
-
Weber, A.J.1
Soong, G.2
Bryan, R.3
Saba, S.4
Prince, A.5
-
23
-
-
0034997191
-
Proinflammatory cytokine responses to P. aeruginosa infection in human airway epithelial cell lines
-
Kube, D.; Sontich, U.; Fletcher, D. and Davis, P.B. (2001) Proinflammatory cytokine responses to P. aeruginosa infection in human airway epithelial cell lines. Am. J. Physiol. Lung Cell. Mol. Physiol., 280, L493-L502.
-
(2001)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.280
-
-
Kube, D.1
Sontich, U.2
Fletcher, D.3
Davis, P.B.4
-
24
-
-
0036840478
-
Inflammatory response in airway epithelial cells isolated from patients with cystic fibrosis
-
Aldallal, N.; McNaughton, E.E.; Manzel, L.J.; Richards, A.M.; Zabner, J.; Ferkol, T.W. and Look, D.C. (2002) Inflammatory response in airway epithelial cells isolated from patients with cystic fibrosis. Am. J. Respir. Crit Care Med., 166, 1248-1256.
-
(2002)
Am. J. Respir. Crit Care Med.
, vol.166
, pp. 1248-1256
-
-
Aldallal, N.1
McNaughton, E.E.2
Manzel, L.J.3
Richards, A.M.4
Zabner, J.5
Ferkol, T.W.6
Look, D.C.7
-
25
-
-
1442325340
-
Cytokine secretion by cystic fibrosis airway epithelial cells
-
Becker, M.N.; Sauer, M.S.; Muhlebach, M.S.; Hirsh, A.J.; Wu, Q.; Verghese, M.W. and Randell, S.H. (2004) Cytokine secretion by cystic fibrosis airway epithelial cells. Am. J. Respir. Crit. Care Med., 169, 645-653.
-
(2004)
Am. J. Respir. Crit. Care Med.
, vol.169
, pp. 645-653
-
-
Becker, M.N.1
Sauer, M.S.2
Muhlebach, M.S.3
Hirsh, A.J.4
Wu, Q.5
Verghese, M.W.6
Randell, S.H.7
-
26
-
-
33646469375
-
Dysregulated interleukin-8 secretion and NF-kappaB activity in human cystic fibrosis nasal epithelial cells
-
Carrabino, S.; Carpani, D.; Livraghi, A.; Di Cicco, M.; Costantini, D.; Copreni, E.; Colombo, C. and Conese, M. (2006) Dysregulated interleukin-8 secretion and NF-kappaB activity in human cystic fibrosis nasal epithelial cells. J. Cyst. Fibros., 5, 113-119.
-
(2006)
J. Cyst. Fibros.
, vol.5
, pp. 113-119
-
-
Carrabino, S.1
Carpani, D.2
Livraghi, A.3
Di Cicco, M.4
Costantini, D.5
Copreni, E.6
Colombo, C.7
Conese, M.8
-
27
-
-
0035002033
-
Dysregulated cytokine production in human cystic fibrosis bronchial epithelial cells
-
Stecenko, A.A.; King, G.; Torii, K.; Breyer, R.M.; Dworski, R.; Blackwell, T.S.; Christman, J.W. and Brigham, K.L. (2001) Dysregulated cytokine production in human cystic fibrosis bronchial epithelial cells. Inflammation, 25, 145-155.
-
(2001)
Inflammation
, vol.25
, pp. 145-155
-
-
Stecenko, A.A.1
King, G.2
Torii, K.3
Breyer, R.M.4
Dworski, R.5
Blackwell, T.S.6
Christman, J.W.7
Brigham, K.L.8
-
28
-
-
33847025695
-
CFTR inhibition mimics the cystic fibrosis inflammatory profile
-
Perez, A.; Issler, A.C.; Cotton, C.U.; Kelley, T.J.; Verkman, A.S. and Davis, P.B. (2007) CFTR inhibition mimics the cystic fibrosis inflammatory profile. Am. J. Physiol. Lung Cell Mol. Physiol., 292, L383-L395.
-
(2007)
Am. J. Physiol. Lung Cell Mol. Physiol.
, vol.292
-
-
Perez, A.1
Issler, A.C.2
Cotton, C.U.3
Kelley, T.J.4
Verkman, A.S.5
Davis, P.B.6
-
29
-
-
77955382245
-
Expression of wild-type CFTR suppresses NF-kappaB-driven inflammatory signalling
-
Hunter, M.J.; Treharne, K.J.; Winter, A.K.; Cassidy, D.M.; Land, S. and Mehta, A. (2010) Expression of wild-type CFTR suppresses NF-kappaB-driven inflammatory signalling. PLoS One, 5, e11598.
-
(2010)
PLoS One
, vol.5
-
-
Hunter, M.J.1
Treharne, K.J.2
Winter, A.K.3
Cassidy, D.M.4
Land, S.5
Mehta, A.6
-
30
-
-
84864288310
-
CFTR is a negative regulator of NFkappaB mediated innate immune response
-
Vij, N.; Mazur, S. and Zeitlin, P.L. (2009) CFTR is a negative regulator of NFkappaB mediated innate immune response. PLoS One, 4, e4664.
-
(2009)
PLoS One
, vol.4
-
-
Vij, N.1
Mazur, S.2
Zeitlin, P.L.3
-
31
-
-
0346103721
-
Localization of cystic fibrosis transmembrane conductance regulator to lipid rafts of epithelial cells is required for Pseudomonas aeruginosa-induced cellular activation
-
Kowalski, M.P. and Pier, G.B. (2004) Localization of cystic fibrosis transmembrane conductance regulator to lipid rafts of epithelial cells is required for Pseudomonas aeruginosa-induced cellular activation. J. Immunol., 172, 418-425.
-
(2004)
J. Immunol.
, vol.172
, pp. 418-425
-
-
Kowalski, M.P.1
Pier, G.B.2
-
32
-
-
0006422025
-
The innate immune response of the respiratory epithelium
-
Diamond, G.; Legarda, D.; Ryan, L.K. (2000) The innate immune response of the respiratory epithelium. Immunol. Rev., 173, 27-38.
-
(2000)
Immunol. Rev.
, vol.173
, pp. 27-38
-
-
Diamond, G.1
Legarda, D.2
Ryan, L.K.3
-
33
-
-
1042269503
-
Innate immunity in the lung: How epithelial cells fight against respiratory pathogens
-
Bals, R. and Hiemstra, P.S. (2004) Innate immunity in the lung: how epithelial cells fight against respiratory pathogens. Eur. Respir. J., 23, 327-333.
-
(2004)
Eur. Respir. J.
, vol.23
, pp. 327-333
-
-
Bals, R.1
Hiemstra, P.S.2
-
34
-
-
2942544512
-
Toll-like receptors in normal and cystic fibrosis airway epithelial cells
-
Muir, A.; Soong, G.; Sokol, S.; Reddy, B.; Gomez, M.I.; Van Heeckeren, A. and Prince, A. (2004) Toll-like receptors in normal and cystic fibrosis airway epithelial cells. Am. J. Respir. Cell. Mol. Biol., 30, 777-783.
-
(2004)
Am. J. Respir. Cell. Mol. Biol.
, vol.30
, pp. 777-783
-
-
Muir, A.1
Soong, G.2
Sokol, S.3
Reddy, B.4
Gomez, M.I.5
van Heeckeren, A.6
Prince, A.7
-
35
-
-
0012929728
-
Toll-like receptors
-
Takeda, K.; Kaisho, T. and Akira, S. (2003) Toll-like receptors. Annu. Rev. Immunol., 21, 335-376.
-
(2003)
Annu. Rev. Immunol.
, vol.21
, pp. 335-376
-
-
Takeda, K.1
Kaisho, T.2
Akira, S.3
-
36
-
-
0038018539
-
Neutrophil elastase up-regulates interleukin-8 via toll-like receptor 4
-
Devaney, J.M.; Greene, C.M.; Taggart, C.C.; Carroll, T.P.; O'Neill, S.J. and McElvaney, N.G. (2003) Neutrophil elastase up-regulates interleukin-8 via toll-like receptor 4. FEBS Lett., 544, 129-132.
-
(2003)
FEBS Lett
, vol.544
, pp. 129-132
-
-
Devaney, J.M.1
Greene, C.M.2
Taggart, C.C.3
Carroll, T.P.4
O'Neill, S.J.5
McElvaney, N.G.6
-
37
-
-
12444341944
-
Toll-like receptors in innate immunity
-
Takeda, K. and Akira, S. (2005) Toll-like receptors in innate immunity. Int. Immunol., 17, 1-14.
-
(2005)
Int. Immunol.
, vol.17
, pp. 1-14
-
-
Takeda, K.1
Akira, S.2
-
38
-
-
0032482752
-
MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta
-
Lee, F.S.; Peters, R.T.; Dang, L.C. and Maniatis, T. (1998) MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta. Proc. Natl. Acad. Sci. USA, 95, 9319-9324.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 9319-9324
-
-
Lee, F.S.1
Peters, R.T.2
Dang, L.C.3
Maniatis, T.4
-
39
-
-
0033605575
-
Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta
-
Zhao, Q. and Lee, F.S. (1999) Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta. J. Biol. Chem., 274, 8355-8358.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8355-8358
-
-
Zhao, Q.1
Lee, F.S.2
-
40
-
-
12444322678
-
TLRinduced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells
-
Greene, C.M.; Carroll, T.P.; Smith, S.G.; Taggart, C.C.; Devaney, J.; Griffin, S.; O'Neill, S.J. and McElvaney, N.G. (2005) TLRinduced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells. J. Immunol., 174, 1638-1646.
-
(2005)
J. Immunol.
, vol.174
, pp. 1638-1646
-
-
Greene, C.M.1
Carroll, T.P.2
Smith, S.G.3
Taggart, C.C.4
Devaney, J.5
Griffin, S.6
O'Neill, S.J.7
McElvaney, N.G.8
-
41
-
-
0037308173
-
Signaling intermediates required for NFkappa B activation and IL-8 expression in CF bronchial epithelial cells
-
Li, J.; Johnson, X.D.; Iazvovskaia, S.; Tan, A.; Lin, A. and Hershenson, M.B. (2003) Signaling intermediates required for NFkappa B activation and IL-8 expression in CF bronchial epithelial cells. Am. J. Physiol. Lung Cell Mol. Physiol., 284, L307-L315.
-
(2003)
Am. J. Physiol. Lung Cell Mol. Physiol.
, vol.284
-
-
Li, J.1
Johnson, X.D.2
Iazvovskaia, S.3
Tan, A.4
Lin, A.5
Hershenson, M.B.6
-
42
-
-
0032510596
-
Activation of NF-kappaB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells
-
Li, J.D.; Feng, W.; Gallup, M.; Kim, J.H.; Gum, J.; Kim, Y. and Basbaum, C. (1998) Activation of NF-kappaB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells. Proc. Natl. Acad. Sci. USA, 95, 5718-5723.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 5718-5723
-
-
Li, J.D.1
Feng, W.2
Gallup, M.3
Kim, J.H.4
Gum, J.5
Kim, Y.6
Basbaum, C.7
-
43
-
-
0036005866
-
DeltaF508-CFTR causes constitutive NF-kappaB activation through an ER-overload response in cystic fibrosis lungs
-
Knorre, A.; Wagner, M.; Schaefer, H.E.; Colledge, W.H. and Pahl, H.L. (2002) DeltaF508-CFTR causes constitutive NF-kappaB activation through an ER-overload response in cystic fibrosis lungs. Biol. Chem., 383, 271-282.
-
(2002)
Biol. Chem.
, vol.383
, pp. 271-282
-
-
Knorre, A.1
Wagner, M.2
Schaefer, H.E.3
Colledge, W.H.4
Pahl, H.L.5
-
44
-
-
34247557545
-
Role of IKK and ERK pathways in intrinsic inflammation of cystic fibrosis airways
-
Verhaeghe, C.; Remouchamps, C.; Hennuy, B.; Vanderplasschen, A.; Chariot, A.; Tabruyn, S.P.; Oury, C. and Bours, V. (2007) Role of IKK and ERK pathways in intrinsic inflammation of cystic fibrosis airways. Biochem. Pharmacol., 73, 1982-1994.
-
(2007)
Biochem. Pharmacol.
, vol.73
, pp. 1982-1994
-
-
Verhaeghe, C.1
Remouchamps, C.2
Hennuy, B.3
Vanderplasschen, A.4
Chariot, A.5
Tabruyn, S.P.6
Oury, C.7
Bours, V.8
-
45
-
-
34247106830
-
Enhanced IL-1betainduced IL-8 production in cystic fibrosis lung epithelial cells is dependent of both mitogen-activated protein kinases and NFkappaB signaling
-
Muselet-Charlier, C.; Roque, T.; Boncoeur, E.; Chadelat, K.; Clement, A.; Jacquot, J. and Tabary, O. (2007) Enhanced IL-1betainduced IL-8 production in cystic fibrosis lung epithelial cells is dependent of both mitogen-activated protein kinases and NFkappaB signaling. Biochem. Biophys. Res. Commun., 357, 402-407.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.357
, pp. 402-407
-
-
Muselet-Charlier, C.1
Roque, T.2
Boncoeur, E.3
Chadelat, K.4
Clement, A.5
Jacquot, J.6
Tabary, O.7
-
46
-
-
77954603744
-
Loss of cystic fibrosis transmembrane conductance regulator function enhances activation of p38 and ERK MAPKs, increasing interleukin-6 synthesis in airway epithelial cells exposed to Pseudomonas aeruginosa
-
Berube, J.; Roussel, L.; Nattagh, L. and Rousseau, S. (2010) Loss of cystic fibrosis transmembrane conductance regulator function enhances activation of p38 and ERK MAPKs, increasing interleukin-6 synthesis in airway epithelial cells exposed to Pseudomonas aeruginosa. J. Biol. Chem., 285, 22299-22307.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 22299-22307
-
-
Berube, J.1
Roussel, L.2
Nattagh, L.3
Rousseau, S.4
-
47
-
-
32244441372
-
The role of intracellular calcium signals in inflammatory responses of polarised cystic fibrosis human airway epithelia
-
Ribeiro, C.M. (2006) The role of intracellular calcium signals in inflammatory responses of polarised cystic fibrosis human airway epithelia. Drugs R. D., 7, 17-31.
-
(2006)
Drugs R. D.
, vol.7
, pp. 17-31
-
-
Ribeiro, C.M.1
-
48
-
-
30944432774
-
Calcium-dependent regulation of NF-(kappa)B activation in cystic fibrosis airway epithelial cells
-
Tabary, O.; Boncoeur, E.; de Martin, R.; Pepperkok, R.; Clement, A.; Schultz, C. and Jacquot, J. (2006) Calcium-dependent regulation of NF-(kappa)B activation in cystic fibrosis airway epithelial cells. Cell Signal, 18, 652-660.
-
(2006)
Cell Signal
, vol.18
, pp. 652-660
-
-
Tabary, O.1
Boncoeur, E.2
de Martin, R.3
Pepperkok, R.4
Clement, A.5
Schultz, C.6
Jacquot, J.7
-
50
-
-
0033846368
-
In vivo alterations of IFN regulatory factor-1 and PIAS1 protein levels in cystic fibrosis epithelium
-
Kelley, T.J. and Elmer, H.L. (2000) In vivo alterations of IFN regulatory factor-1 and PIAS1 protein levels in cystic fibrosis epithelium. J. Clin. Invest., 106, 403-410.
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 403-410
-
-
Kelley, T.J.1
Elmer, H.L.2
-
51
-
-
3242702434
-
Impaired nitric oxide synthase-2 signaling pathway in cystic fibrosis airway epithelium
-
Zheng, S.; Xu, W.; Bose, S.; Banerjee, A.K.; Haque, S.J. and Erzurum, S.C. (2004) Impaired nitric oxide synthase-2 signaling pathway in cystic fibrosis airway epithelium. Am. J. Physiol. Lung Cell. Mol. Physiol., 287, L374-L381.
-
(2004)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.287
-
-
Zheng, S.1
Xu, W.2
Bose, S.3
Banerjee, A.K.4
Haque, S.J.5
Erzurum, S.C.6
-
52
-
-
0037407805
-
Effects of nitric oxide on Pseudomonas aeruginosa infection of epithelial cells from a human respiratory cell line derived from a patient with cystic fibrosis
-
Darling, K.E. and Evans, T.J. (2003) Effects of nitric oxide on Pseudomonas aeruginosa infection of epithelial cells from a human respiratory cell line derived from a patient with cystic fibrosis. Infect. Immun., 71, 2341-2349.
-
(2003)
Infect. Immun.
, vol.71
, pp. 2341-2349
-
-
Darling, K.E.1
Evans, T.J.2
-
53
-
-
0037728657
-
Impaired innate host defense causes susceptibility to respiratory virus infections in cystic fibrosis
-
Zheng, S.; De Bishnu, P.; Choudhary, S.; Comhair, S.A.; Goggans, T.; Slee, R.; Williams, B.R.; Pilewski, J.; Haque, S.J. and Erzurum, S.C. (2003) Impaired innate host defense causes susceptibility to respiratory virus infections in cystic fibrosis. Immunity, 18, 619-630.
-
(2003)
Immunity
, vol.18
, pp. 619-630
-
-
Zheng, S.1
de Bishnu, P.2
Choudhary, S.3
Comhair, S.A.4
Goggans, T.5
Slee, R.6
Williams, B.R.7
Pilewski, J.8
Haque, S.J.9
Erzurum, S.C.10
-
54
-
-
0032964751
-
Nitric oxide reduces the sequestration of polymorphonuclear leukocytes in lung by changing deformability and CD18 expression
-
Sato, Y.; Walley, K.R.; Klut, M.E.; English, D.; D'Yachkova, Y.; Hogg, J.C. and van Eeden, S.F. (1999) Nitric oxide reduces the sequestration of polymorphonuclear leukocytes in lung by changing deformability and CD18 expression. Am. J. Respir. Crit. Care Med., 159, 1469-1476.
-
(1999)
Am. J. Respir. Crit. Care Med.
, vol.159
, pp. 1469-1476
-
-
Sato, Y.1
Walley, K.R.2
Klut, M.E.3
English, D.4
D'Yachkova, Y.5
Hogg, J.C.6
van Eeden, S.F.7
-
55
-
-
0347318128
-
Direct oxidation of 2', 7'-dichlorodihydrofluorescein by pyocyanin and other redox-active compounds independent of reactive oxygen species production
-
O'Malley, Y.Q.; Reszka, K.J. and Britigan, B.E. (2004) Direct oxidation of 2', 7'-dichlorodihydrofluorescein by pyocyanin and other redox-active compounds independent of reactive oxygen species production. Free Radic. Biol. Med., 36, 90-100.
-
(2004)
Free Radic. Biol. Med.
, vol.36
, pp. 90-100
-
-
O'Malley, Y.Q.1
Reszka, K.J.2
Britigan, B.E.3
-
56
-
-
54949110924
-
Exhaled 8-isoprostane and prostaglandin E(2) in patients with stable and unstable cystic fibrosis
-
Lucidi, V.; Ciabattoni, G.; Bella, S.; Barnes, P.J. and Montuschi, P. (2008) Exhaled 8-isoprostane and prostaglandin E(2) in patients with stable and unstable cystic fibrosis. Free Radic. Biol. Med., 45, 913-919.
-
(2008)
Free Radic. Biol. Med.
, vol.45
, pp. 913-919
-
-
Lucidi, V.1
Ciabattoni, G.2
Bella, S.3
Barnes, P.J.4
Montuschi, P.5
-
57
-
-
54249153391
-
Biomarkers in exhaled breath condensate indicate presence and severity of cystic fibrosis in children
-
Robroeks, C.M.; Rosias, P.P.; van Vliet, D.; Jobsis, Q.; Yntema, J.B.; Brackel, H.J.; Damoiseaux, J.G.; den Hartog, G.M.; Wodzig, W.K. and Dompeling, E. (2008) Biomarkers in exhaled breath condensate indicate presence and severity of cystic fibrosis in children. Pediatr. Allergy Immunol., 19, 652-659.
-
(2008)
Pediatr. Allergy Immunol.
, vol.19
, pp. 652-659
-
-
Robroeks, C.M.1
Rosias, P.P.2
van Vliet, D.3
Jobsis, Q.4
Yntema, J.B.5
Brackel, H.J.6
Damoiseaux, J.G.7
den Hartog, G.M.8
Wodzig, W.K.9
Dompeling, E.10
-
58
-
-
33344476292
-
Oxidative changes of bronchoalveolar proteins in cystic fibrosis
-
Starosta, V.; Rietschel, E.; Paul, K.; Baumann, U. and Griese, M. (2006) Oxidative changes of bronchoalveolar proteins in cystic fibrosis. Chest, 129, 431-437.
-
(2006)
Chest
, vol.129
, pp. 431-437
-
-
Starosta, V.1
Rietschel, E.2
Paul, K.3
Baumann, U.4
Griese, M.5
-
59
-
-
10644263047
-
Myeloperoxidase and protein oxidation in the airways of young children with cystic fibrosis
-
Kettle, A.J.; Chan, T.; Osberg, I.; Senthilmohan, R.; Chapman, A.L.; Mocatta, T.J. and Wagener, J.S. (2004) Myeloperoxidase and protein oxidation in the airways of young children with cystic fibrosis. Am. J. Respir. Crit. Care Med., 170, 1317-1323.
-
(2004)
Am. J. Respir. Crit. Care Med.
, vol.170
, pp. 1317-1323
-
-
Kettle, A.J.1
Chan, T.2
Osberg, I.3
Senthilmohan, R.4
Chapman, A.L.5
Mocatta, T.J.6
Wagener, J.S.7
-
60
-
-
33750737798
-
Mitochondrial oxidative stress in the lungs of cystic fibrosis transmembrane conductance regulator protein mutant mice
-
Velsor, L.W.; Kariya, C.; Kachadourian, R. and Day, B.J. (2006) Mitochondrial oxidative stress in the lungs of cystic fibrosis transmembrane conductance regulator protein mutant mice. Am. J. Respir. Cell. Mol. Biol., 35, 579-586.
-
(2006)
Am. J. Respir. Cell. Mol. Biol.
, vol.35
, pp. 579-586
-
-
Velsor, L.W.1
Kariya, C.2
Kachadourian, R.3
Day, B.J.4
-
61
-
-
0034816784
-
Antioxidant imbalance in the lungs of cystic fibrosis transmembrane conductance regulator protein mutant mice
-
Velsor, L.W.; van Heeckeren, A. and Day, B.J. (2001) Antioxidant imbalance in the lungs of cystic fibrosis transmembrane conductance regulator protein mutant mice. Am. J. Physiol. Lung Cell. Mol. Physiol., 281, L31-L38.
-
(2001)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.281
-
-
Velsor, L.W.1
van Heeckeren, A.2
Day, B.J.3
-
62
-
-
33644833034
-
Oxidant stress suppresses CFTR expression
-
Cantin, A.M.; Bilodeau, G.; Ouellet, C.; Liao, J. and Hanrahan, J.W. (2006) Oxidant stress suppresses CFTR expression. Am. J. Physiol. Cell Physiol., 290, C262-C270.
-
(2006)
Am. J. Physiol. Cell Physiol.
, vol.290
-
-
Cantin, A.M.1
Bilodeau, G.2
Ouellet, C.3
Liao, J.4
Hanrahan, J.W.5
-
63
-
-
46949105608
-
Airway epithelial cell inflammatory signalling in cystic fibrosis
-
Jacquot, J.; Tabary, O.; Le Rouzic, P. and Clement, A. (2008) Airway epithelial cell inflammatory signalling in cystic fibrosis. Int. J. Biochem. Cell Biol., 40, 1703-1715.
-
(2008)
Int. J. Biochem. Cell Biol.
, vol.40
, pp. 1703-1715
-
-
Jacquot, J.1
Tabary, O.2
Le Rouzic, P.3
Clement, A.4
-
64
-
-
67650682128
-
Peroxiredoxin 6 fails to limit phospholipid peroxidation in lung from Cftr-knockout mice subjected to oxidative challenge
-
Trudel, S.; Kelly, M.; Fritsch, J.; Nguyen-Khoa, T.; Therond, P.; Couturier, M.; Dadlez, M.; Debski, J.; Touqui, L.; Vallee, B.; Ollero, M.; Edelman, A. and Brouillard, F. (2009) Peroxiredoxin 6 fails to limit phospholipid peroxidation in lung from Cftr-knockout mice subjected to oxidative challenge. PLoS One, 4, e6075.
-
(2009)
PLoS One
, vol.4
-
-
Trudel, S.1
Kelly, M.2
Fritsch, J.3
Nguyen-Khoa, T.4
Therond, P.5
Couturier, M.6
Dadlez, M.7
Debski, J.8
Touqui, L.9
Vallee, B.10
Ollero, M.11
Edelman, A.12
Brouillard, F.13
-
65
-
-
0027742895
-
Systemic deficiency of glutathione in cystic fibrosis
-
Roum, J.H.; Buhl, R.; McElvaney, N.G.; Borok, Z. and Crystal, R.G. (1993) Systemic deficiency of glutathione in cystic fibrosis. J. Appl. Physiol., 75, 2419-2424.
-
(1993)
J. Appl. Physiol.
, vol.75
, pp. 2419-2424
-
-
Roum, J.H.1
Buhl, R.2
McElvaney, N.G.3
Borok, Z.4
Crystal, R.G.5
-
66
-
-
0344258132
-
Abnormal glutathione transport in cystic fibrosis airway epithelia
-
Gao, L.; Kim, K.J.; Yankaskas, J.R. and Forman, H.J. (1999) Abnormal glutathione transport in cystic fibrosis airway epithelia. Am. J. Physiol., 277, L113-L118.
-
(1999)
Am. J. Physiol.
, vol.277
-
-
Gao, L.1
Kim, K.J.2
Yankaskas, J.R.3
Forman, H.J.4
-
67
-
-
0035876878
-
Rethinking cystic fibrosis pathology: The critical role of abnormal reduced glutathione (GSH) transport caused by CFTR mutation
-
Hudson, V.M. (2001) Rethinking cystic fibrosis pathology: the critical role of abnormal reduced glutathione (GSH) transport caused by CFTR mutation. Free Radic. Biol. Med., 30, 1440-1461.
-
(2001)
Free Radic. Biol. Med.
, vol.30
, pp. 1440-1461
-
-
Hudson, V.M.1
-
68
-
-
41849092177
-
Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis
-
Teichgraber, V.; Ulrich, M.; Endlich, N.; Riethmuller, J.; Wilker, B.; De Oliveira-Munding, C.C.; van Heeckeren, A.M.; Barr, M.L.; von Kurthy, G.; Schmid, K.W.; Weller, M.; Tummler, B.; Lang, F.; Grassme, H.; Doring, G. and Gulbins, E. (2008) Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis. Nat. Med., 14, 382-391.
-
(2008)
Nat. Med.
, vol.14
, pp. 382-391
-
-
Teichgraber, V.1
Ulrich, M.2
Endlich, N.3
Riethmuller, J.4
Wilker, B.5
de Oliveira-Munding, C.C.6
van Heeckeren, A.M.7
Barr, M.L.8
von Kurthy, G.9
Schmid, K.W.10
Weller, M.11
Tummler, B.12
Lang, F.13
Grassme, H.14
Doring, G.15
Gulbins, E.16
-
69
-
-
0033884050
-
Compartmentalization of ceramide signaling: Physical foundations and biological effects
-
Kolesnick, R.N.; Goni, F.M. and Alonso, A. (2000) Compartmentalization of ceramide signaling: physical foundations and biological effects. J. Cell Physiol., 184, 285-300.
-
(2000)
J. Cell Physiol.
, vol.184
, pp. 285-300
-
-
Kolesnick, R.N.1
Goni, F.M.2
Alonso, A.3
-
70
-
-
58349116453
-
Cystic fibrosis and innate immunity: How chloride channel mutations provoke lung disease
-
Doring, G. and Gulbins, E. (2009) Cystic fibrosis and innate immunity: how chloride channel mutations provoke lung disease. Cell Microbiol., 11, 208-216.
-
(2009)
Cell Microbiol
, vol.11
, pp. 208-216
-
-
Doring, G.1
Gulbins, E.2
-
71
-
-
37549012987
-
Fenretinide corrects newly found ceramide deficiency in cystic fibrosis
-
Guilbault, C.; De Sanctis, J.B.; Wojewodka, G.; Saeed, Z.; Lachance, C.; Skinner, T.A.; Vilela, R.M.; Kubow, S.; Lands, L.C.; Hajduch, M.; Matouk, E. and Radzioch, D. (2008) Fenretinide corrects newly found ceramide deficiency in cystic fibrosis. Am. J. Respir. Cell Mol. Biol., 38, 47-56.
-
(2008)
Am. J. Respir. Cell Mol. Biol.
, vol.38
, pp. 47-56
-
-
Guilbault, C.1
de Sanctis, J.B.2
Wojewodka, G.3
Saeed, Z.4
Lachance, C.5
Skinner, T.A.6
Vilela, R.M.7
Kubow, S.8
Lands, L.C.9
Hajduch, M.10
Matouk, E.11
Radzioch, D.12
-
72
-
-
77953251984
-
Acid sphingomyelinase inhibitors normalize pulmonary ceramide and inflammation in cystic fibrosis
-
Becker, K.A.; Riethmuller, J.; Luth, A.; Doring, G.; Kleuser, B. and Gulbins, E. (2010) Acid sphingomyelinase inhibitors normalize pulmonary ceramide and inflammation in cystic fibrosis. Am. J. Respir. Cell Mol. Biol., 42, 716-724.
-
(2010)
Am. J. Respir. Cell Mol. Biol.
, vol.42
, pp. 716-724
-
-
Becker, K.A.1
Riethmuller, J.2
Luth, A.3
Doring, G.4
Kleuser, B.5
Gulbins, E.6
-
73
-
-
70149091116
-
SUMOylation of tissue transglutaminase as link between oxidative stress and inflammation
-
Luciani, A.; Villella, V.R.; Vasaturo, A.; Giardino, I.; Raia, V.; Pettoello-Mantovani, M.; D'Apolito, M.; Guido, S.; Leal, T.; Quaratino, S. and Maiuri, L. (2009) SUMOylation of tissue transglutaminase as link between oxidative stress and inflammation. J. Immunol., 183, 2775-2784.
-
(2009)
J. Immunol.
, vol.183
, pp. 2775-2784
-
-
Luciani, A.1
Villella, V.R.2
Vasaturo, A.3
Giardino, I.4
Raia, V.5
Pettoello-Mantovani, M.6
D'Apolito, M.7
Guido, S.8
Leal, T.9
Quaratino, S.10
Maiuri, L.11
-
75
-
-
78149475088
-
Regulation of Mammalian autophagy in physiology and pathophysiology
-
Ravikumar, B.; Sarkar, S.; Davies, J.E.; Futter, M.; Garcia- Arencibia, M.; Green-Thompson, Z.W.; Jimenez-Sanchez, M.; Korolchuk, V.I.; Lichtenberg, M.; Luo, S.; Massey, D.C.; Menzies, F.M.; Moreau, K.; Narayanan, U.; Renna, M.; Siddiqi, F.H.; Underwood, B.R.; Winslow, A.R. and Rubinsztein, D.C. (2010) Regulation of Mammalian autophagy in physiology and pathophysiology. Physiol. Rev., 90, 1383-1435.
-
(2010)
Physiol. Rev.
, vol.90
, pp. 1383-1435
-
-
Ravikumar, B.1
Sarkar, S.2
Davies, J.E.3
Futter, M.4
Garcia-Arencibia, M.5
Green-Thompson, Z.W.6
Jimenez-Sanchez, M.7
Korolchuk, V.I.8
Lichtenberg, M.9
Luo, S.10
Massey, D.C.11
Menzies, F.M.12
Moreau, K.13
Narayanan, U.14
Renna, M.15
Siddiqi, F.H.16
Underwood, B.R.17
Winslow, A.R.18
Rubinsztein, D.C.19
-
76
-
-
77956396747
-
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition
-
Luciani, A.; Villella, V.R.; Esposito, S.; Brunetti-Pierri, N.; Medina, D.; Settembre, C.; Gavina, M.; Pulze, L.; Giardino, I.; Pettoello-Mantovani, M.; D'Apolito, M.; Guido, S.; Masliah, E.; Spencer, B.; Quaratino, S.; Raia, V.; Ballabio, A. and Maiuri, L. (2010) Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition. Nat. Cell Biol., 12, 863-875.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 863-875
-
-
Luciani, A.1
Villella, V.R.2
Esposito, S.3
Brunetti-Pierri, N.4
Medina, D.5
Settembre, C.6
Gavina, M.7
Pulze, L.8
Giardino, I.9
Pettoello-Mantovani, M.10
D'Apolito, M.11
Guido, S.12
Masliah, E.13
Spencer, B.14
Quaratino, S.15
Raia, V.16
Ballabio, A.17
Maiuri, L.18
-
77
-
-
1542617932
-
Cutting edge: Myeloid differentiation factor 88 is essential for pulmonary host defense against Pseudomonas aeruginosa but not Staphylococcus aureus
-
Skerrett, S.J.; Liggitt, H.D.; Hajjar, A.M. and Wilson, C.B. (2004) Cutting edge: myeloid differentiation factor 88 is essential for pulmonary host defense against Pseudomonas aeruginosa but not Staphylococcus aureus. J. Immunol., 172, 3377-3381.
-
(2004)
J. Immunol.
, vol.172
, pp. 3377-3381
-
-
Skerrett, S.J.1
Liggitt, H.D.2
Hajjar, A.M.3
Wilson, C.B.4
-
78
-
-
0033915314
-
Role of pulmonary alveolar macrophages in defense of the lung against Pseudomonas aeruginosa
-
Cheung, D.O.Y.; Halsey, K. and Speert, D.P. (2000) Role of pulmonary alveolar macrophages in defense of the lung against Pseudomonas aeruginosa. Infect. Immun., 68, 4585-4592.
-
(2000)
Infect. Immun.
, vol.68
, pp. 4585-4592
-
-
Cheung, D.O.Y.1
Halsey, K.2
Speert, D.P.3
-
79
-
-
0141958113
-
Defective phagocytosis and clearance of Pseudomonas aeruginosa in the lung following bone marrow transplantation
-
Ojielo, C.I.; Cooke, K.; Mancuso, P.; Standiford, T.J.; Olkiewicz, K.M.; Clouthier, S.; Corrion, L.; Ballinger, M.N.; Toews, G.B.; Paine, R. 3rd. and Moore, B.B. (2003) Defective phagocytosis and clearance of Pseudomonas aeruginosa in the lung following bone marrow transplantation. J. Immunol., 171, 4416-4424.
-
(2003)
J. Immunol.
, vol.171
, pp. 4416-4424
-
-
Ojielo, C.I.1
Cooke, K.2
Mancuso, P.3
Standiford, T.J.4
Olkiewicz, K.M.5
Clouthier, S.6
Corrion, L.7
Ballinger, M.N.8
Toews, G.B.9
Paine III, R.10
Moore, B.B.11
-
80
-
-
15844425585
-
Depletion of alveolar macrophages decreases neutrophil chemotaxis to Pseudomonas airspace infections
-
Hashimoto, S.; Pittet, J.F.; Hong, K.; Folkesson, H.; Bagby, G.; Kobzik, L.; Frevert, C.; Watanabe, K.; Tsurufuji, S. and Wiener- Kronish, J. (1996) Depletion of alveolar macrophages decreases neutrophil chemotaxis to Pseudomonas airspace infections. Am. J. Physiol. Lung Cell. Mol. Physiol., 270, L819-L828.
-
(1996)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.270
-
-
Hashimoto, S.1
Pittet, J.F.2
Hong, K.3
Folkesson, H.4
Bagby, G.5
Kobzik, L.6
Frevert, C.7
Watanabe, K.8
Tsurufuji, S.9
Wiener-Kronish, J.10
-
81
-
-
0031813752
-
Role of alveolar macrophages in initiation and regulation of inflammation in Pseudomonas aeruginosa pneumonia
-
Kooguchi, K.; Hashimoto, S.; Kobayashi, A.; Kitamura, Y.; Kudoh, I.; Wiener-Kronish, J. and Sawa, T. (1998) Role of alveolar macrophages in initiation and regulation of inflammation in Pseudomonas aeruginosa pneumonia. Infect. Immun., 66, 3164-3169.
-
(1998)
Infect. Immun.
, vol.66
, pp. 3164-3169
-
-
Kooguchi, K.1
Hashimoto, S.2
Kobayashi, A.3
Kitamura, Y.4
Kudoh, I.5
Wiener-Kronish, J.6
Sawa, T.7
-
82
-
-
0029085705
-
Bacterial stimulators of macrophages
-
Hauschildt, S. and Kleine, B. (1995) Bacterial stimulators of macrophages. Int. Rev. Cytol., 161, 263-331.
-
(1995)
Int. Rev. Cytol.
, vol.161
, pp. 263-331
-
-
Hauschildt, S.1
Kleine, B.2
-
83
-
-
0028236526
-
Granulocyte/macrophage colony-stimulating factordeficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology
-
Stanley, E.; Lieschke, G.J.; Grail, D.; Metcalf, D.; Hodgson, G.; Gall, J.A.; Maher, D.W.; Cebon, J.; Sinickas, V. and Dunn, A.R. (1994) Granulocyte/macrophage colony-stimulating factordeficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology. Proc. Natl. Acad. Sci. USA, 91, 5592-5596.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 5592-5596
-
-
Stanley, E.1
Lieschke, G.J.2
Grail, D.3
Metcalf, D.4
Hodgson, G.5
Gall, J.A.6
Maher, D.W.7
Cebon, J.8
Sinickas, V.9
Dunn, A.R.10
-
84
-
-
0036201268
-
Gm-CSF regulates pulmonary surfactant homeostasis and alveolar macrophagemediated innate host defense
-
Trapnell, B.C. and Whitsett, J.A. (2002) Gm-CSF regulates pulmonary surfactant homeostasis and alveolar macrophagemediated innate host defense. Annu. Rev. Physiol., 64, 775-802.
-
(2002)
Annu. Rev. Physiol.
, vol.64
, pp. 775-802
-
-
Trapnell, B.C.1
Whitsett, J.A.2
-
85
-
-
0029967842
-
Surfactant metabolism in transgenic mice after granulocyte macrophage-colony stimulating factor ablation
-
Ikegami, M.; Ueda, T.; Hull, W.; Whitsett, J.A.; Mulligan, R.C.; Dranoff, G. and Jobe, A.H. (1996) Surfactant metabolism in transgenic mice after granulocyte macrophage-colony stimulating factor ablation. Am. J. Physiol., 270, L650-L658.
-
(1996)
Am. J. Physiol.
, vol.270
-
-
Ikegami, M.1
Ueda, T.2
Hull, W.3
Whitsett, J.A.4
Mulligan, R.C.5
Dranoff, G.6
Jobe, A.H.7
-
86
-
-
0028263504
-
Involvement of granulocytemacrophage colony-stimulating factor in pulmonary homeostasis
-
Dranoff, G.; Crawford, A.D.; Sadelain, M.; Ream, B.; Rashid, A.; Bronson, R.T.; Dickersin, G.R.; Bachurski, C.J.; Mark, E.L.; Whitsett, J.A. and Mulligan, R.C. (1994) Involvement of granulocytemacrophage colony-stimulating factor in pulmonary homeostasis. Science, 264, 713-716.
-
(1994)
Science
, vol.264
, pp. 713-716
-
-
Dranoff, G.1
Crawford, A.D.2
Sadelain, M.3
Ream, B.4
Rashid, A.5
Bronson, R.T.6
Dickersin, G.R.7
Bachurski, C.J.8
Mark, E.L.9
Whitsett, J.A.10
Mulligan, R.C.11
-
87
-
-
0033557298
-
GM-CSF-deficient mice are susceptible to pulmonary group B streptococcal infection
-
LeVine, A.M.; Reed, J.A.; Kurak, K.E.; Cianciolo, E. and Whitsett, J.A. (1999) GM-CSF-deficient mice are susceptible to pulmonary group B streptococcal infection. J. Clin. Invest., 103, 563-569.
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 563-569
-
-
Levine, A.M.1
Reed, J.A.2
Kurak, K.E.3
Cianciolo, E.4
Whitsett, J.A.5
-
88
-
-
0034161743
-
Granulocyte-macrophage colony-stimulating factor in the innate immune response to Pneumocystis carinii pneumonia in mice
-
Paine, R. 3rd; Preston, A.M.; Wilcoxen, S.; Jin, H.; Siu, B.B.; Morris, S.B.; Reed, J.A.; Ross, G.; Whitsett, J.A. and Beck, J.M. (2000) Granulocyte-macrophage colony-stimulating factor in the innate immune response to Pneumocystis carinii pneumonia in mice. J. Immunol., 164, 2602-2609.
-
(2000)
J. Immunol.
, vol.164
, pp. 2602-2609
-
-
Paine III, R.1
Preston, A.M.2
Wilcoxen, S.3
Jin, H.4
Siu, B.B.5
Morris, S.B.6
Reed, J.A.7
Ross, G.8
Whitsett, J.A.9
Beck, J.M.10
-
89
-
-
20044379240
-
Disruption of granulocyte macrophage-colony stimulating factor production in the lungs severely affects the ability of mice to control Mycobacterium tuberculosis infection
-
Gonzalez-Juarrero, M.; Hattle, J.M.; Izzo, A.; Junqueira-Kipnis, A.P.; Shim, T.S.; Trapnell, B.C.; Cooper, A.M. and Orme, I.M. (2005) Disruption of granulocyte macrophage-colony stimulating factor production in the lungs severely affects the ability of mice to control Mycobacterium tuberculosis infection. J. Leukoc. Biol., 77, 914-922.
-
(2005)
J. Leukoc. Biol.
, vol.77
, pp. 914-922
-
-
Gonzalez-Juarrero, M.1
Hattle, J.M.2
Izzo, A.3
Junqueira-Kipnis, A.P.4
Shim, T.S.5
Trapnell, B.C.6
Cooper, A.M.7
Orme, I.M.8
-
90
-
-
33744722811
-
Role of granulocyte macrophage colony-stimulating factor during gram-negative lung infection with Pseudomonas aeruginosa
-
Ballinger, M.N.; Paine, R. 3rd; Serezani, C.H.; Aronoff, D.M.; Choi, E.S.; Standiford, T.J.; Toews, G.B. and Moore, B.B. (2006) Role of granulocyte macrophage colony-stimulating factor during gram-negative lung infection with Pseudomonas aeruginosa. Am. J. Respir. Cell. Mol. Biol., 34, 766-774.
-
(2006)
Am. J. Respir. Cell. Mol. Biol.
, vol.34
, pp. 766-774
-
-
Ballinger, M.N.1
Paine III, R.2
Serezani, C.H.3
Aronoff, D.M.4
Choi, E.S.5
Standiford, T.J.6
Toews, G.B.7
Moore, B.B.8
-
91
-
-
0034748924
-
GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.1
-
Shibata, Y.; Berclaz, P.Y.; Chroneos, Z.C.; Yoshida, M.; Whitsett, J.A. and Trapnell, B.C. (2001) GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.1. Immunity, 15, 557-567.
-
(2001)
Immunity
, vol.15
, pp. 557-567
-
-
Shibata, Y.1
Berclaz, P.Y.2
Chroneos, Z.C.3
Yoshida, M.4
Whitsett, J.A.5
Trapnell, B.C.6
-
92
-
-
33846101642
-
GM-CSF regulates a PU.1-dependent transcriptional program determining the pulmonary response to LPS
-
Berclaz, P.Y.; Carey, B.; Fillipi, M.D.; Wernke-Dollries, K.; Geraci, N.; Cush, S.; Richardson, T.; Kitzmiller, J.; O'Connor, M.; Hermoyian, C.; Korfhagen, T.; Whitsett, J.A. and Trapnell, B.C. (2007) GM-CSF regulates a PU.1-dependent transcriptional program determining the pulmonary response to LPS. Am. J. Respir. Cell Mol. Biol., 36, 114-121.
-
(2007)
Am. J. Respir. Cell Mol. Biol.
, vol.36
, pp. 114-121
-
-
Berclaz, P.Y.1
Carey, B.2
Fillipi, M.D.3
Wernke-Dollries, K.4
Geraci, N.5
Cush, S.6
Richardson, T.7
Kitzmiller, J.8
O'Connor, M.9
Hermoyian, C.10
Korfhagen, T.11
Whitsett, J.A.12
Trapnell, B.C.13
-
93
-
-
0030893651
-
Cytokine concentrations in sputum from patients with cystic fibrosis and their relation to eosinophil activity
-
Koller, D.Y.; Nething, I.; Otto, J.; Urbanek, R. and Eichler, I. (1997) Cytokine concentrations in sputum from patients with cystic fibrosis and their relation to eosinophil activity. Am. J. Respir. Crit. Care Med., 155, 1050-1054.
-
(1997)
Am. J. Respir. Crit. Care Med.
, vol.155
, pp. 1050-1054
-
-
Koller, D.Y.1
Nething, I.2
Otto, J.3
Urbanek, R.4
Eichler, I.5
-
94
-
-
22044442105
-
Serum concentrations of GM-CSF and G-CSF correlate with the Th1/Th2 cytokine response in cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection
-
Moser, C.; Jensen, P.O.; Pressler, T.; Frederiksen, B.; Lanng, S.; Kharazmi, A.; Koch, C. and Hoiby, N. (2005) Serum concentrations of GM-CSF and G-CSF correlate with the Th1/Th2 cytokine response in cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection. Apmis, 113, 400-409.
-
(2005)
Apmis
, vol.113
, pp. 400-409
-
-
Moser, C.1
Jensen, P.O.2
Pressler, T.3
Frederiksen, B.4
Lanng, S.5
Kharazmi, A.6
Koch, C.7
Hoiby, N.8
-
95
-
-
33746161139
-
Increased serum concentration of G-CSF in cystic fibrosis patients with chronic Pseudomonas aeruginosa pneumonia
-
Jensen, P.O.; Moser, C.; Kharazmi, A.; Presler, T.; Koch, C. and Hoiby, N. (2006) Increased serum concentration of G-CSF in cystic fibrosis patients with chronic Pseudomonas aeruginosa pneumonia. J. Cyst. Fibros., 5, 145-151.
-
(2006)
J. Cyst. Fibros.
, vol.5
, pp. 145-151
-
-
Jensen, P.O.1
Moser, C.2
Kharazmi, A.3
Presler, T.4
Koch, C.5
Hoiby, N.6
-
96
-
-
40349087455
-
Neutrophils in cystic fibrosis display a distinct gene expression pattern
-
Adib-Conquy, M.; Pedron, T.; Petit-Bertron, A.F.; Tabary, O.; Corvol, H.; Jacquot, J.; Clement, A. and Cavaillon, J.M. (2008) Neutrophils in cystic fibrosis display a distinct gene expression pattern. Mol. Med., 14, 36-44.
-
(2008)
Mol. Med.
, vol.14
, pp. 36-44
-
-
Adib-Conquy, M.1
Pedron, T.2
Petit-Bertron, A.F.3
Tabary, O.4
Corvol, H.5
Jacquot, J.6
Clement, A.7
Cavaillon, J.M.8
-
97
-
-
33748146503
-
CFTR regulates phagosome acidification in macrophages and alters bactericidal activity
-
Di, A.; Brown, M.E.; Deriy, L.V.; Li, C.; Szeto, F.L.; Chen, Y.; Huang, P.; Tong, J.; Naren, A.P.; Bindokas, V.; Palfrey, H.C. and Nelson, D.J. (2006) CFTR regulates phagosome acidification in macrophages and alters bactericidal activity. Nat. Cell Biol., 8, 933-944.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 933-944
-
-
Di, A.1
Brown, M.E.2
Deriy, L.V.3
Li, C.4
Szeto, F.L.5
Chen, Y.6
Huang, P.7
Tong, J.8
Naren, A.P.9
Bindokas, V.10
Palfrey, H.C.11
Nelson, D.J.12
-
98
-
-
35748973573
-
Cystic fibrosis transmembrane conductance regulator-independent phagosomal acidification in macrophages
-
Haggie, P.M. and Verkman, A.S. (2007) Cystic fibrosis transmembrane conductance regulator-independent phagosomal acidification in macrophages. J. Biol. Chem., 282, 31422-31428.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 31422-31428
-
-
Haggie, P.M.1
Verkman, A.S.2
-
99
-
-
77954504913
-
Alterations in ceramide concentration and pH determine the release of reactive oxygen species by Cftr-deficient macrophages on infection
-
Zhang, Y.; Li, X.; Grassme, H.; Doring, G. and Gulbins, E. (2010) Alterations in ceramide concentration and pH determine the release of reactive oxygen species by Cftr-deficient macrophages on infection. J. Immunol., 184, 5104-5111.
-
(2010)
J. Immunol.
, vol.184
, pp. 5104-5111
-
-
Zhang, Y.1
Li, X.2
Grassme, H.3
Doring, G.4
Gulbins, E.5
-
100
-
-
0033937232
-
The immune response to chronic Pseudomonas aeruginosa lung infection in cystic fibrosis patients is predominantly of the Th2 type
-
Moser, C.; Kjaergaard, S.; Pressler, T.; Kharazmi, A.; Koch, C. and Hoiby, N. (2000) The immune response to chronic Pseudomonas aeruginosa lung infection in cystic fibrosis patients is predominantly of the Th2 type. Apmis, 108, 329-335.
-
(2000)
Apmis
, vol.108
, pp. 329-335
-
-
Moser, C.1
Kjaergaard, S.2
Pressler, T.3
Kharazmi, A.4
Koch, C.5
Hoiby, N.6
-
101
-
-
29544436136
-
Pulmonary T(H)2 response in Pseudomonas aeruginosa-infected patients with cystic fibrosis
-
Hartl, D.; Griese, M.; Kappler, M.; Zissel, G.; Reinhardt, D.; Rebhan, C.; Schendel, D.J. and Krauss-Etschmann, S. (2006) Pulmonary T(H)2 response in Pseudomonas aeruginosa-infected patients with cystic fibrosis. J. Allergy Clin. Immunol., 117, 204-211.
-
(2006)
J. Allergy Clin. Immunol.
, vol.117
, pp. 204-211
-
-
Hartl, D.1
Griese, M.2
Kappler, M.3
Zissel, G.4
Reinhardt, D.5
Rebhan, C.6
Schendel, D.J.7
Krauss-Etschmann, S.8
-
102
-
-
77956898288
-
Characterization of macrophage activation states in patients with cystic fibrosis
-
Murphy, B.S.; Bush, H.M.; Sundareshan, V.; Davis, C.; Hagadone, J.; Cory, T.J.; Hoy, H.; Hayes, D.Jr.; Anstead, M.I. and Feola, D.J. (2010) Characterization of macrophage activation states in patients with cystic fibrosis. J. Cyst. Fibros., 9, 314-322.
-
(2010)
J. Cyst. Fibros.
, vol.9
, pp. 314-322
-
-
Murphy, B.S.1
Bush, H.M.2
Sundareshan, V.3
Davis, C.4
Hagadone, J.5
Cory, T.J.6
Hoy, H.7
Hayes Jr., D.8
Anstead, M.I.9
Feola, D.J.10
-
103
-
-
34347396792
-
Is cystic fibrosis a TH17 disease?
-
Dubin, P.J.; McAllister, F. and Kolls, J.K. (2007) Is cystic fibrosis a TH17 disease? Inflamm. Res., 56, 221-227.
-
(2007)
Inflamm. Res.
, vol.56
, pp. 221-227
-
-
Dubin, P.J.1
McAllister, F.2
Kolls, J.K.3
-
104
-
-
21244455537
-
Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: Implications for airway inflammation in cystic fibrosis
-
McAllister, F.; Henry, A.; Kreindler, J.L.; Dubin, P.J.; Ulrich, L.; Steele, C.; Finder, J.D.; Pilewski, J.M.; Carreno, B.M.; Goldman, S.J.; Pirhonen, J. and Kolls, J.K. (2005) Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis. J. Immunol., 175, 404-412.
-
(2005)
J. Immunol.
, vol.175
, pp. 404-412
-
-
McAllister, F.1
Henry, A.2
Kreindler, J.L.3
Dubin, P.J.4
Ulrich, L.5
Steele, C.6
Finder, J.D.7
Pilewski, J.M.8
Carreno, B.M.9
Goldman, S.J.10
Pirhonen, J.11
Kolls, J.K.12
-
105
-
-
0038172655
-
Distinct cytokine production by lung and blood neutrophils from children with cystic fibrosis
-
Corvol, H.; Fitting, C.; Chadelat, K.; Jacquot, J.; Tabary, O.; Boule, M.; Cavaillon, J.M. and Clement, A. (2003) Distinct cytokine production by lung and blood neutrophils from children with cystic fibrosis. Am. J. Physiol. Lung Cell. Mol. Physiol., 284, L997-L1003.
-
(2003)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.284
-
-
Corvol, H.1
Fitting, C.2
Chadelat, K.3
Jacquot, J.4
Tabary, O.5
Boule, M.6
Cavaillon, J.M.7
Clement, A.8
-
106
-
-
65249151394
-
Activation of critical, hostinduced, metabolic and stress pathways marks neutrophil entry into cystic fibrosis lungs
-
Makam, M.; Diaz, D.; Laval, J.; Gernez, Y.; Conrad, C.K.; Dunn, C.E.; Davies, Z.A.; Moss, R. B.; Herzenberg, L.A.; Herzenberg, L.A. and Tirouvanziam, R. (2009) Activation of critical, hostinduced, metabolic and stress pathways marks neutrophil entry into cystic fibrosis lungs. Proc. Natl. Acad. Sci. USA, 106, 5779-5783.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 5779-5783
-
-
Makam, M.1
Diaz, D.2
Laval, J.3
Gernez, Y.4
Conrad, C.K.5
Dunn, C.E.6
Davies, Z.A.7
Moss, R.B.8
Herzenberg, L.A.9
Herzenberg, L.A.10
Tirouvanziam, R.11
-
107
-
-
41949120305
-
Profound functional and signaling changes in viable inflammatory neutrophils homing to cystic fibrosis airways
-
Tirouvanziam, R.; Gernez, Y.; Conrad, C.K.; Moss, R.B.; Schrijver, I.; Dunn, C.E.; Davies, Z.A.; Herzenberg, L.A. and Herzenberg, L.A. (2008) Profound functional and signaling changes in viable inflammatory neutrophils homing to cystic fibrosis airways. Proc. Natl. Acad. Sci. USA, 105, 4335-4339.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 4335-4339
-
-
Tirouvanziam, R.1
Gernez, Y.2
Conrad, C.K.3
Moss, R.B.4
Schrijver, I.5
Dunn, C.E.6
Davies, Z.A.7
Herzenberg, L.A.8
Herzenberg, L.A.9
-
108
-
-
37449031035
-
Circulating and airway neutrophils in cystic fibrosis display different TLR expression and responsiveness to interleukin-10
-
Petit-Bertron, A.F.; Tabary, O.; Corvol, H.; Jacquot, J.; Clement, A.; Cavaillon, J.M. and Adib-Conquy, M. (2008) Circulating and airway neutrophils in cystic fibrosis display different TLR expression and responsiveness to interleukin-10. Cytokine, 41, 54-60.
-
(2008)
Cytokine
, vol.41
, pp. 54-60
-
-
Petit-Bertron, A.F.1
Tabary, O.2
Corvol, H.3
Jacquot, J.4
Clement, A.5
Cavaillon, J.M.6
Adib-Conquy, M.7
-
109
-
-
0042360446
-
Neutrophil recruitment and airway epithelial cell involvement in chronic cystic fibrosis lung disease
-
Conese, M.; Copreni, E.; Di Gioia, S.; De Rinaldis, P. and Fumarulo, R. (2003) Neutrophil recruitment and airway epithelial cell involvement in chronic cystic fibrosis lung disease. J. Cyst. Fibros., 2, 129-135.
-
(2003)
J. Cyst. Fibros.
, vol.2
, pp. 129-135
-
-
Conese, M.1
Copreni, E.2
Di Gioia, S.3
de Rinaldis, P.4
Fumarulo, R.5
-
110
-
-
58349104978
-
Neutrophils in cystic fibrosis
-
Downey, D.G.; Bell, S.C. and Elborn, J.S. (2009) Neutrophils in cystic fibrosis. Thorax, 64, 81-88.
-
(2009)
Thorax
, vol.64
, pp. 81-88
-
-
Downey, D.G.1
Bell, S.C.2
Elborn, J.S.3
-
111
-
-
23744490412
-
Neutrophil cell death, activation and bacterial infection in cystic fibrosis
-
Watt, A.P.; Courtney, J.; Moore, J.; Ennis, M. and Elborn, J.S. (2005) Neutrophil cell death, activation and bacterial infection in cystic fibrosis. Thorax, 60, 659-664.
-
(2005)
Thorax
, vol.60
, pp. 659-664
-
-
Watt, A.P.1
Courtney, J.2
Moore, J.3
Ennis, M.4
Elborn, J.S.5
-
112
-
-
0036195343
-
Elastase-mediated phosphatidylserine receptor cleavage impairs apoptotic cell clearance in cystic fibrosis and bronchiectasis
-
Vandivier, R.W.; Fadok, V.A.; Hoffmann, P.R.; Bratton, D.L.; Penvari, C.; Brown, K.K.; Brain, J.D.; Accurso, F.J. and Henson, P.M. (2002) Elastase-mediated phosphatidylserine receptor cleavage impairs apoptotic cell clearance in cystic fibrosis and bronchiectasis. J. Clin. Invest., 109, 661-670.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 661-670
-
-
Vandivier, R.W.1
Fadok, V.A.2
Hoffmann, P.R.3
Bratton, D.L.4
Penvari, C.5
Brown, K.K.6
Brain, J.D.7
Accurso, F.J.8
Henson, P.M.9
-
113
-
-
70349759567
-
Dysfunctional cystic fibrosis transmembrane conductance regulator inhibits phagocytosis of apoptotic cells with proinflammatory consequences
-
Vandivier, R.W.; Richens, T.R.; Horstmann, S.A.; deCathelineau, A.M.; Ghosh, M.; Reynolds, S.D.; Xiao, Y.Q.; Riches, D.W.; Plumb, J.; Vachon, E.; Downey, G.P. and Henson, P.M. (2009) Dysfunctional cystic fibrosis transmembrane conductance regulator inhibits phagocytosis of apoptotic cells with proinflammatory consequences. Am. J. Physiol. Lung Cell. Mol. Physiol., 297, L677- L686.
-
(2009)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.297
-
-
Vandivier, R.W.1
Richens, T.R.2
Horstmann, S.A.3
Decathelineau, A.M.4
Ghosh, M.5
Reynolds, S.D.6
Xiao, Y.Q.7
Riches, D.W.8
Plumb, J.9
Vachon, E.10
Downey, G.P.11
Henson, P.M.12
-
114
-
-
33644936021
-
Adherence of airway neutrophils and inflammatory response are increased in CF airway epithelial cell-neutrophil interactions
-
Tabary, O.; Corvol, H.; Boncoeur, E.; Chadelat, K.; Fitting, C.; Cavaillon, J.M.; Clement, A. and Jacquot, J. (2006) Adherence of airway neutrophils and inflammatory response are increased in CF airway epithelial cell-neutrophil interactions. Am. J. Physiol. Lung Cell. Mol. Physiol., 290, L588-L596.
-
(2006)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.290
-
-
Tabary, O.1
Corvol, H.2
Boncoeur, E.3
Chadelat, K.4
Fitting, C.5
Cavaillon, J.M.6
Clement, A.7
Jacquot, J.8
-
115
-
-
36849020586
-
Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease
-
Hartl, D.; Latzin, P.; Hordijk, P.; Marcos, V.; Rudolph, C.; Woischnik, M.; Krauss-Etschmann, S.; Koller, B.; Reinhardt, D.; Roscher, A.A.; Roos, D. and Griese, M. (2007) Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease. Nat. Med., 13, 1423-1430.
-
(2007)
Nat. Med.
, vol.13
, pp. 1423-1430
-
-
Hartl, D.1
Latzin, P.2
Hordijk, P.3
Marcos, V.4
Rudolph, C.5
Woischnik, M.6
Krauss-Etschmann, S.7
Koller, B.8
Reinhardt, D.9
Roscher, A.A.10
Roos, D.11
Griese, M.12
-
116
-
-
21144459960
-
Enhanced Pseudomonas aeruginosa biofilm development mediated by human neutrophils
-
Walker, T.S.; Tomlin, K.L.; Worthen, G.S.; Poch, K.R.; Lieber, J.G.; Saavedra, M.T.; Fessler, M.B.; Malcolm, K.C.; Vasil, M.L. and Nick, J.A. (2005) Enhanced Pseudomonas aeruginosa biofilm development mediated by human neutrophils. Infect. Immun., 73, 3693-3701.
-
(2005)
Infect. Immun.
, vol.73
, pp. 3693-3701
-
-
Walker, T.S.1
Tomlin, K.L.2
Worthen, G.S.3
Poch, K.R.4
Lieber, J.G.5
Saavedra, M.T.6
Fessler, M.B.7
Malcolm, K.C.8
Vasil, M.L.9
Nick, J.A.10
-
117
-
-
0034999076
-
Quantitative analysis of inflammatory cells infiltrating the cystic fibrosis airway mucosa
-
Hubeau, C.; Lorenzato, M.; Couetil, J.P.; Hubert, D.; Dusser, D.; Puchelle, E. and Gaillard, D. (2001) Quantitative analysis of inflammatory cells infiltrating the cystic fibrosis airway mucosa. Clin. Exp. Immunol., 124, 69-76.
-
(2001)
Clin. Exp. Immunol.
, vol.124
, pp. 69-76
-
-
Hubeau, C.1
Lorenzato, M.2
Couetil, J.P.3
Hubert, D.4
Dusser, D.5
Puchelle, E.6
Gaillard, D.7
-
118
-
-
34447525439
-
Beneficial suicide: Why neutrophils die to make NETs
-
Brinkmann, V. and Zychlinsky, A. (2007) Beneficial suicide: why neutrophils die to make NETs. Nat. Rev. Microbiol., 5, 577-582.
-
(2007)
Nat. Rev. Microbiol.
, vol.5
, pp. 577-582
-
-
Brinkmann, V.1
Zychlinsky, A.2
-
119
-
-
1542287347
-
Neutrophil extracellular traps kill bacteria
-
Brinkmann, V.; Reichard, U.; Goosmann, C.; Fauler, B.; Uhlemann, Y.; Weiss, D.S.; Weinrauch, Y. and Zychlinsky, A. (2004) Neutrophil extracellular traps kill bacteria. Science, 303, 1532-1535.
-
(2004)
Science
, vol.303
, pp. 1532-1535
-
-
Brinkmann, V.1
Reichard, U.2
Goosmann, C.3
Fauler, B.4
Uhlemann, Y.5
Weiss, D.S.6
Weinrauch, Y.7
Zychlinsky, A.8
-
120
-
-
32944465559
-
DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps
-
Buchanan, J.T.; Simpson, A.J.; Aziz, R.K.; Liu, G.Y.; Kristian, S.A.; Kotb, M.; Feramisco, J. and Nizet, V. (2006) DNase expression allows the pathogen group A Streptococcus to escape killing in neutrophil extracellular traps. Curr. Biol., 16, 396-400.
-
(2006)
Curr. Biol.
, vol.16
, pp. 396-400
-
-
Buchanan, J.T.1
Simpson, A.J.2
Aziz, R.K.3
Liu, G.Y.4
Kristian, S.A.5
Kotb, M.6
Feramisco, J.7
Nizet, V.8
-
121
-
-
34147188469
-
Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood
-
Clark, S.R.; Ma, A.C.; Tavener, S.A.; McDonald, B.; Goodarzi, Z.; Kelly, M.M.; Patel, K.D.; Chakrabarti, S.; McAvoy, E.; Sinclair, G.D.; Keys, E.M.; Allen-Vercoe, E.; Devinney, R.; Doig, C.J.; Green, F.H. and Kubes, P. (2007) Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood. Nat. Med., 13, 463-469.
-
(2007)
Nat. Med.
, vol.13
, pp. 463-469
-
-
Clark, S.R.1
Ma, A.C.2
Tavener, S.A.3
McDonald, B.4
Goodarzi, Z.5
Kelly, M.M.6
Patel, K.D.7
Chakrabarti, S.8
McAvoy, E.9
Sinclair, G.D.10
Keys, E.M.11
Allen-Vercoe, E.12
Devinney, R.13
Doig, C.J.14
Green, F.H.15
Kubes, P.16
-
122
-
-
32944463724
-
Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms
-
Urban, C.F.; Reichard, U.; Brinkmann, V. and Zychlinsky, A. (2006) Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms. Cell. Microbiol., 8, 668-676.
-
(2006)
Cell. Microbiol.
, vol.8
, pp. 668-676
-
-
Urban, C.F.1
Reichard, U.2
Brinkmann, V.3
Zychlinsky, A.4
-
123
-
-
73649099522
-
Neutrophil extracellular traps contain calprotectin, a cytosolic protein complex involved in host defense against Candida albicans
-
Urban, C.F.; Ermert, D.; Schmid, M.; Abu-Abed, U.; Goosmann, C.; Nacken, W.; Brinkmann, V.; Jungblut, P.R. and Zychlinsky, A. (2009) Neutrophil extracellular traps contain calprotectin, a cytosolic protein complex involved in host defense against Candida albicans. PLoS Pathog., 5, e1000639.
-
(2009)
PLoS Pathog
, vol.5
-
-
Urban, C.F.1
Ermert, D.2
Schmid, M.3
Abu-Abed, U.4
Goosmann, C.5
Nacken, W.6
Brinkmann, V.7
Jungblut, P.R.8
Zychlinsky, A.9
-
124
-
-
67349279881
-
Netting neutrophils in autoimmune small-vessel vasculitis
-
Kessenbrock, K.; Krumbholz, M.; Schonermarck, U.; Back, W.; Gross, W.L.; Werb, Z.; Grone, H.J.; Brinkmann, V. and Jenne, D.E. (2009) Netting neutrophils in autoimmune small-vessel vasculitis. Nat. Med., 15, 623-625.
-
(2009)
Nat. Med.
, vol.15
, pp. 623-625
-
-
Kessenbrock, K.1
Krumbholz, M.2
Schonermarck, U.3
Back, W.4
Gross, W.L.5
Werb, Z.6
Grone, H.J.7
Brinkmann, V.8
Jenne, D.E.9
-
125
-
-
77953088427
-
Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis
-
Hakkim, A.; Furnrohr, B.G.; Amann, K.; Laube, B.; Abed, U.A.; Brinkmann, V.; Herrmann, M.; Voll, R.E. and Zychlinsky, A. (2010) Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis. Proc. Natl. Acad. Sci. USA, 107, 9813-9318.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 9813-9318
-
-
Hakkim, A.1
Furnrohr, B.G.2
Amann, K.3
Laube, B.4
Abed, U.A.5
Brinkmann, V.6
Herrmann, M.7
Voll, R.E.8
Zychlinsky, A.9
-
126
-
-
77956426154
-
CXCR2 mediates NADPH oxidaseindependent neutrophil extracellular trap formation in cystic fibrosis airway inflammation
-
Marcos, V.; Zhou, Z.; Yildirim, A.O.; Bohla, A.; Hector, A.; Vitkov, L.; Wiedenbauer, E. M.; Krautgartner, W.D.; Stoiber, W.; Belohradsky, B.H.; Rieber, N.; Kormann, M.; Koller, B.; Roscher, A.; Roos, D.; Griese, M.; Eickelberg, O.; Doring, G.; Mall, M.A. and Hartl, D. (2010) CXCR2 mediates NADPH oxidaseindependent neutrophil extracellular trap formation in cystic fibrosis airway inflammation. Nat. Med., 16, 1018-1023.
-
(2010)
Nat. Med.
, vol.16
, pp. 1018-1023
-
-
Marcos, V.1
Zhou, Z.2
Yildirim, A.O.3
Bohla, A.4
Hector, A.5
Vitkov, L.6
Wiedenbauer, E.M.7
Krautgartner, W.D.8
Stoiber, W.9
Belohradsky, B.H.10
Rieber, N.11
Kormann, M.12
Koller, B.13
Roscher, A.14
Roos, D.15
Griese, M.16
Eickelberg, O.17
Doring, G.18
Mall, M.A.19
Hartl, D.20
more..
-
127
-
-
77956705683
-
Isolation and characterization of microparticles in sputum of cystic fibrosis patients
-
Porro, C.; Lepore, S.; Trotta, T.; Castellani, S.; Ratclif, L.; Battaglino, A.; Di Gioia, S.; Martinez, M.C.; Conese, M. and Maffione, A.B. (2010) Isolation and characterization of microparticles in sputum of cystic fibrosis patients. Respir. Res., 11, 94.
-
(2010)
Respir. Res.
, vol.11
, pp. 94
-
-
Porro, C.1
Lepore, S.2
Trotta, T.3
Castellani, S.4
Ratclif, L.5
Battaglino, A.6
Di Gioia, S.7
Martinez, M.C.8
Conese, M.9
Maffione, A.B.10
-
128
-
-
33645234855
-
Induction of neutrophil extracellular DNA lattices by placental microparticles and IL-8 and their presence in preeclampsia
-
Gupta, A.K.; Hasler, P.; Holzgreve, W.; Gebhardt, S. and Hahn, S. (2005) Induction of neutrophil extracellular DNA lattices by placental microparticles and IL-8 and their presence in preeclampsia. Hum. Immunol., 66, 1146-1154.
-
(2005)
Hum. Immunol.
, vol.66
, pp. 1146-1154
-
-
Gupta, A.K.1
Hasler, P.2
Holzgreve, W.3
Gebhardt, S.4
Hahn, S.5
-
129
-
-
65949116148
-
New genetic and pharmacological treatments for cystic fibrosis
-
Conese, M.; Romano, M.; Furnari, M.L.; Copreni, E.; de Fino, I.; Pardo, F.; Galietta, L.V.J. (2009) New genetic and pharmacological treatments for cystic fibrosis. Curr. Ped. Rev., 5, 8-27.
-
(2009)
Curr. Ped. Rev.
, vol.5
, pp. 8-27
-
-
Conese, M.1
Romano, M.2
Furnari, M.L.3
Copreni, E.4
de Fino, I.5
Pardo, F.6
Galietta, L.V.J.7
-
130
-
-
70350475798
-
A pipeline of therapies for cystic fibrosis
-
Ashlock, M.A.; Beall, R.J.; Hamblett, N.M.; Konstan, M.W.; Penland, C.M.; Ramsey, B.W.; Van Dalfsen, J.M.; Wetmore, D.R. and Campbell, P.W. 3rd. (2009) A pipeline of therapies for cystic fibrosis. Semin. Respir. Crit. Care Med., 30, 611-626.
-
(2009)
Semin. Respir. Crit. Care Med.
, vol.30
, pp. 611-626
-
-
Ashlock, M.A.1
Beall, R.J.2
Hamblett, N.M.3
Konstan, M.W.4
Penland, C.M.5
Ramsey, B.W.6
van Dalfsen, J.M.7
Wetmore, D.R.8
Campbell III, P.W.9
-
131
-
-
4944260975
-
Lung inflammation as a therapeutic target in cystic fibrosis
-
Koehler, D.R.; Downey, G.P.; Sweezey, N.B.; Tanswell, A.K. and Hu, J. (2004) Lung inflammation as a therapeutic target in cystic fibrosis. Am. J. Respir. Cell Mol. Biol., 31, 377-381.
-
(2004)
Am. J. Respir. Cell Mol. Biol.
, vol.31
, pp. 377-381
-
-
Koehler, D.R.1
Downey, G.P.2
Sweezey, N.B.3
Tanswell, A.K.4
Hu, J.5
-
132
-
-
59449089139
-
Antiinflammatory therapies for cystic fibrosis-related lung disease
-
Nichols, D.P.; Konstan, M.W. and Chmiel, J.F. (2008) Antiinflammatory therapies for cystic fibrosis-related lung disease. Clin. Rev. Allergy Immunol., 35, 135-153.
-
(2008)
Clin. Rev. Allergy Immunol.
, vol.35
, pp. 135-153
-
-
Nichols, D.P.1
Konstan, M.W.2
Chmiel, J.F.3
-
133
-
-
77956624118
-
The NF-kappaB signaling in cystic fibrosis lung disease: Pathophysiology and therapeutic potential
-
Bodas, M. and Vij, N. The NF-kappaB signaling in cystic fibrosis lung disease: pathophysiology and therapeutic potential. Discov. Med., 9, 346-356.
-
Discov. Med.
, vol.9
, pp. 346-356
-
-
Bodas, M.1
Vij, N.2
-
134
-
-
0035976575
-
Prostaglandins and leukotrienes: Advances in eicosanoid biology
-
Funk, C.D. (2001) Prostaglandins and leukotrienes: advances in eicosanoid biology. Science, 294, 1871-1875.
-
(2001)
Science
, vol.294
, pp. 1871-1875
-
-
Funk, C.D.1
-
135
-
-
25444468323
-
Leukotriene B4 receptor and the function of its helix 8
-
Okuno, T.; Yokomizo, T.; Hori, T.; Miyano, M. and Shimizu, T. (2005) Leukotriene B4 receptor and the function of its helix 8. J. Biol. Chem., 280, 32049-32052.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 32049-32052
-
-
Okuno, T.1
Yokomizo, T.2
Hori, T.3
Miyano, M.4
Shimizu, T.5
-
136
-
-
0037528819
-
Increased leukotriene B4 and interleukin-6 in exhaled breath condensate in cystic fibrosis
-
Carpagnano, G.E.; Barnes, P.J.; Geddes, D.M.; Hodson, M.E. and Kharitonov, S.A. (2003) Increased leukotriene B4 and interleukin-6 in exhaled breath condensate in cystic fibrosis. Am. J. Respir. Crit. Care Med., 167, 1109-1112.
-
(2003)
Am. J. Respir. Crit. Care Med.
, vol.167
, pp. 1109-1112
-
-
Carpagnano, G.E.1
Barnes, P.J.2
Geddes, D.M.3
Hodson, M.E.4
Kharitonov, S.A.5
-
137
-
-
29144528654
-
Results of a phase II clinical trial of BIIL 284 BS (a LTB4 receptor antagonist) for the treatment of CF lung disease
-
Konstan, M.W.; Doring, G.; Lands, L.C.; Hilliard, K.A.; Koker, P.; Bhattacharya, B.; Staab, A. and Hamilton, A.L. (2005) Results of a phase II clinical trial of BIIL 284 BS (a LTB4 receptor antagonist) for the treatment of CF lung disease. Ped. Pulmunol., 28, 125-127.
-
(2005)
Ped. Pulmunol.
, vol.28
, pp. 125-127
-
-
Konstan, M.W.1
Doring, G.2
Lands, L.C.3
Hilliard, K.A.4
Koker, P.5
Bhattacharya, B.6
Staab, A.7
Hamilton, A.L.8
-
138
-
-
20144387174
-
Randomized, double-blind, placebo-controlled, doseescalating study of aerosolized interferon gamma-1b in patients with mild to moderate cystic fibrosis lung disease
-
Moss, R.B.; Mayer-Hamblett, N.; Wagener, J.; Daines, C.; Hale, K.; Ahrens, R.; Gibson, R.L.; Anderson, P.; Retsch-Bogart, G.; Nasr, S.Z.; Noth, I.; Waltz, D.; Zeitlin, P.; Ramsey, B. and Starko, K. (2005) Randomized, double-blind, placebo-controlled, doseescalating study of aerosolized interferon gamma-1b in patients with mild to moderate cystic fibrosis lung disease. Pediatr. Pulmonol., 39, 209-218.
-
(2005)
Pediatr. Pulmonol.
, vol.39
, pp. 209-218
-
-
Moss, R.B.1
Mayer-Hamblett, N.2
Wagener, J.3
Daines, C.4
Hale, K.5
Ahrens, R.6
Gibson, R.L.7
Anderson, P.8
Retsch-Bogart, G.9
Nasr, S.Z.10
Noth, I.11
Waltz, D.12
Zeitlin, P.13
Ramsey, B.14
Starko, K.15
-
139
-
-
57549085708
-
Toll-like receptors as therapeutic targets in cystic fibrosis
-
Greene, C.M.; Branagan, P. and McElvaney, N.G. (2008) Toll-like receptors as therapeutic targets in cystic fibrosis. Expert. Opin. Ther. Targets, 12, 1481-1495.
-
(2008)
Expert. Opin. Ther. Targets
, vol.12
, pp. 1481-1495
-
-
Greene, C.M.1
Branagan, P.2
McElvaney, N.G.3
-
140
-
-
0029821647
-
Secretory leukoprotease inhibitor: Partnering alpha 1-proteinase inhibitor to combat pulmonary inflammation
-
Bingle, L. and Tetley, T.D. (1996) Secretory leukoprotease inhibitor: partnering alpha 1-proteinase inhibitor to combat pulmonary inflammation. Thorax, 51, 1273-1274.
-
(1996)
Thorax
, vol.51
, pp. 1273-1274
-
-
Bingle, L.1
Tetley, T.D.2
-
141
-
-
0037072766
-
Secretory leucoprotease inhibitor prevents lipopolysaccharide- induced IkappaBalpha degradation without affecting phosphorylation or ubiquitination
-
Taggart, C.C.; Greene, C.M.; McElvaney, N.G. and O'Neill, S. (2002) Secretory leucoprotease inhibitor prevents lipopolysaccharide- induced IkappaBalpha degradation without affecting phosphorylation or ubiquitination. J. Biol. Chem., 277, 33648-33653.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 33648-33653
-
-
Taggart, C.C.1
Greene, C.M.2
McElvaney, N.G.3
O'Neill, S.4
-
142
-
-
29144439305
-
Secretory leucoprotease inhibitor binds to NF-kappaB binding sites in monocytes and inhibits p65 binding
-
Taggart, C.C.; Cryan, S.A.; Weldon, S.; Gibbons, A.; Greene, C.M.; Kelly, E.; Low, T.B.; O'Neill, S.J. and McElvaney, N.G. (2005) Secretory leucoprotease inhibitor binds to NF-kappaB binding sites in monocytes and inhibits p65 binding. J. Exp. Med., 202, 1659-1668.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 1659-1668
-
-
Taggart, C.C.1
Cryan, S.A.2
Weldon, S.3
Gibbons, A.4
Greene, C.M.5
Kelly, E.6
Low, T.B.7
O'Neill, S.J.8
McElvaney, N.G.9
-
143
-
-
2342464085
-
The two NF-kappaB activation pathways and their role in innate and adaptive immunity
-
Bonizzi, G. and Karin, M. (2004) The two NF-kappaB activation pathways and their role in innate and adaptive immunity. Trends Immunol., 25, 280-288.
-
(2004)
Trends Immunol
, vol.25
, pp. 280-288
-
-
Bonizzi, G.1
Karin, M.2
-
144
-
-
0038266174
-
The role of nuclear factor kappa B in the pathogenesis of pulmonary diseases: Implications for therapy
-
Wright, J.G. and Christman, J.W. (2003) The role of nuclear factor kappa B in the pathogenesis of pulmonary diseases: implications for therapy. Am. J. Respir. Med., 2, 211-219.
-
(2003)
Am. J. Respir. Med.
, vol.2
, pp. 211-219
-
-
Wright, J.G.1
Christman, J.W.2
-
145
-
-
78650648443
-
Targeting transcription factor activity as a strategy to inhibit pro-inflammatory genes involved in cystic fibrosis: Decoy oligonucleotides and low-molecular weight compounds
-
Cabrini, G.; Bezzerri, V.; Mancini, I.; Nicolis, E.; Dechecchi, M.C.; Tamanini, A.; Lampronti, I.; Piccagli, L.; Bianchi, N.; Borgatti, M. and Gambari, R. (2010) Targeting transcription factor activity as a strategy to inhibit pro-inflammatory genes involved in cystic fibrosis: decoy oligonucleotides and low-molecular weight compounds. Curr. Med. Chem., 17, 4392-4404.
-
(2010)
Curr. Med. Chem.
, vol.17
, pp. 4392-4404
-
-
Cabrini, G.1
Bezzerri, V.2
Mancini, I.3
Nicolis, E.4
Dechecchi, M.C.5
Tamanini, A.6
Lampronti, I.7
Piccagli, L.8
Bianchi, N.9
Borgatti, M.10
Gambari, R.11
-
146
-
-
45849120519
-
Transcription factor oligodeoxynucleotides to NF-kappaB inhibit transcription of IL-8 in bronchial cells
-
Bezzerri, V.; Borgatti, M.; Nicolis, E.; Lampronti, I.; Dechecchi, M.C.; Mancini, I.; Rizzotti, P.; Gambari, R. and Cabrini, G. (2008) Transcription factor oligodeoxynucleotides to NF-kappaB inhibit transcription of IL-8 in bronchial cells. Am. J. Respir. Cell Mol. Biol., 39, 86-96.
-
(2008)
Am. J. Respir. Cell Mol. Biol.
, vol.39
, pp. 86-96
-
-
Bezzerri, V.1
Borgatti, M.2
Nicolis, E.3
Lampronti, I.4
Dechecchi, M.C.5
Mancini, I.6
Rizzotti, P.7
Gambari, R.8
Cabrini, G.9
-
147
-
-
52249121789
-
Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: Correlation with inhibition of NF-kappaB/DNA interactions and inhibitory effects on IL-8 gene expression
-
Piccagli, L.; Fabbri, E.; Borgatti, M.; Bezzerri, V.; Mancini, I.; Nicolis, E.; Dechecchi, M.C.; Lampronti, I.; Cabrini, G. and Gambari, R. (2008) Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: correlation with inhibition of NF-kappaB/DNA interactions and inhibitory effects on IL-8 gene expression. BMC Struct. Biol., 8, 38.
-
(2008)
BMC Struct. Biol.
, vol.8
, pp. 38
-
-
Piccagli, L.1
Fabbri, E.2
Borgatti, M.3
Bezzerri, V.4
Mancini, I.5
Nicolis, E.6
Dechecchi, M.C.7
Lampronti, I.8
Cabrini, G.9
Gambari, R.10
-
148
-
-
78249265983
-
Virtual screening against nuclear factor kappaB (NF-kappaB) of a focus library: Identification of bioactive furocoumarin derivatives inhibiting NF-kappaB dependent biological functions involved in cystic fibrosis
-
Piccagli, L.; Borgatti, M.; Nicolis, E.; Bianchi, N.; Mancini, I.; Lampronti, I.; Vevaldi, D.; Dall'acqua, F.; Cabrini, G. and Gambari, R. (2010) Virtual screening against nuclear factor kappaB (NF-kappaB) of a focus library: Identification of bioactive furocoumarin derivatives inhibiting NF-kappaB dependent biological functions involved in cystic fibrosis. Bioorg. Med. Chem., 18, 8341-8349.
-
(2010)
Bioorg. Med. Chem.
, vol.18
, pp. 8341-8349
-
-
Piccagli, L.1
Borgatti, M.2
Nicolis, E.3
Bianchi, N.4
Mancini, I.5
Lampronti, I.6
Vevaldi, D.7
Dall'acqua, F.8
Cabrini, G.9
Gambari, R.10
-
149
-
-
70049114406
-
Cystic fibrosis gene therapy: Successes, failures and hopes for the future
-
Griesenbach, U. and Alton, E.W.F.W. (2009) Cystic fibrosis gene therapy: successes, failures and hopes for the future. Exp. Rev. Resp. Med., 3, 363-371.
-
(2009)
Exp. Rev. Resp. Med.
, vol.3
, pp. 363-371
-
-
Griesenbach, U.1
Alton, E.W.F.W.2
-
150
-
-
42449153440
-
Gene and cell therapy for the treatment of cystic fibrosis
-
Conese, M.; Copreni, E.; Piro, D. and Rejman, J. (2007) Gene and cell therapy for the treatment of cystic fibrosis. Adv. Gene Mol. Cell Ther., 1, 99-119.
-
(2007)
Adv. Gene Mol. Cell Ther.
, vol.1
, pp. 99-119
-
-
Conese, M.1
Copreni, E.2
Piro, D.3
Rejman, J.4
-
151
-
-
33751177801
-
Azithromycin reduces spontaneous and induced inflammation in DeltaF508 cystic fibrosis mice
-
Legssyer, R.; Huaux, F.; Lebacq, J.; Delos, M.; Marbaix, E.; Lebecque, P.; Lison, D.; Scholte, B.J.; Wallemacq, P. and Leal, T. (2006) Azithromycin reduces spontaneous and induced inflammation in DeltaF508 cystic fibrosis mice. Respir. Res., 7, 134.
-
(2006)
Respir. Res.
, vol.7
, pp. 134
-
-
Legssyer, R.1
Huaux, F.2
Lebacq, J.3
Delos, M.4
Marbaix, E.5
Lebecque, P.6
Lison, D.7
Scholte, B.J.8
Wallemacq, P.9
Leal, T.10
-
152
-
-
34548072307
-
N-Acetylcysteine--a safe antidote for cysteine/ glutathione deficiency
-
Atkuri, K.R.; Mantovani, J.J.; Herzenberg, L.A. and Herzenberg, L.A. (2007) N-Acetylcysteine--a safe antidote for cysteine/ glutathione deficiency. Curr. Opin. Pharmacol., 7, 355-359.
-
(2007)
Curr. Opin. Pharmacol.
, vol.7
, pp. 355-359
-
-
Atkuri, K.R.1
Mantovani, J.J.2
Herzenberg, L.A.3
Herzenberg, L.A.4
-
153
-
-
33751580475
-
Antioxidants in cystic fibrosis: Conclusions from the CF antioxidant workshop
-
Bethesda, Maryland, November 11-12, 2003
-
Cantin, A.M.; White, T.B.; Cross, C.E.; Forman, H.J.; Sokol, R.J. and Borowitz, D. (2007) Antioxidants in cystic fibrosis: conclusions from the CF antioxidant workshop, Bethesda, Maryland, November 11-12, 2003. Free Radic. Biol. Med., 42, 15-31.
-
(2007)
Free Radic. Biol. Med.
, vol.42
, pp. 15-31
-
-
Cantin, A.M.1
White, T.B.2
Cross, C.E.3
Forman, H.J.4
Sokol, R.J.5
Borowitz, D.6
-
154
-
-
33645229803
-
High-dose oral Nacetylcysteine, a glutathione prodrug, modulates inflammation in cystic fibrosis
-
Tirouvanziam, R.; Conrad, C.K.; Bottiglieri, T.; Herzenberg, L.A.; Moss, R.B. and Herzenberg, L.A. (2006) High-dose oral Nacetylcysteine, a glutathione prodrug, modulates inflammation in cystic fibrosis. Proc. Natl. Acad. Sci. USA, 103, 4628-4633.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 4628-4633
-
-
Tirouvanziam, R.1
Conrad, C.K.2
Bottiglieri, T.3
Herzenberg, L.A.4
Moss, R.B.5
Herzenberg, L.A.6
-
155
-
-
60149110687
-
The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by nonadhesive polymer nanoparticles
-
Suk, J.S.; Lai, S.K.; Wang, Y.Y.; Ensign, L.M.; Zeitlin, P.L.; Boyle, M.P. and Hanes, J. (2009) The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by nonadhesive polymer nanoparticles. Biomaterials, 30, 2591-2597.
-
(2009)
Biomaterials
, vol.30
, pp. 2591-2597
-
-
Suk, J.S.1
Lai, S.K.2
Wang, Y.Y.3
Ensign, L.M.4
Zeitlin, P.L.5
Boyle, M.P.6
Hanes, J.7
-
156
-
-
67650429993
-
Therapeutic efficacy and safety of amitriptyline in patients with cystic fibrosis
-
Riethmuller, J.; Anthonysamy, J.; Serra, E.; Schwab, M.; Doring, G. and Gulbins, E. (2009) Therapeutic efficacy and safety of amitriptyline in patients with cystic fibrosis. Cell Physiol. Biochem., 24, 65-72.
-
(2009)
Cell Physiol. Biochem.
, vol.24
, pp. 65-72
-
-
Riethmuller, J.1
Anthonysamy, J.2
Serra, E.3
Schwab, M.4
Doring, G.5
Gulbins, E.6
-
157
-
-
10744223051
-
Association of cystic fibrosis with abnormalities in fatty acid metabolism
-
Freedman, S.D.; Blanco, P.G.; Zaman, M.M.; Shea, J.C.; Ollero, M.; Hopper, I.K.; Weed, D.A.; Gelrud, A.; Regan, M.M.; Laposata, M.; Alvarez, J.G. and O'Sullivan, B.P. (2004) Association of cystic fibrosis with abnormalities in fatty acid metabolism. N. Engl. J. Med., 350, 560-569.
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 560-569
-
-
Freedman, S.D.1
Blanco, P.G.2
Zaman, M.M.3
Shea, J.C.4
Ollero, M.5
Hopper, I.K.6
Weed, D.A.7
Gelrud, A.8
Regan, M.M.9
Laposata, M.10
Alvarez, J.G.11
O'Sullivan, B.P.12
-
158
-
-
34247847681
-
Resolution phase of inflammation: Novel endogenous anti-inflammatory and proresolving lipid mediators and pathways
-
Serhan, C.N. (2007) Resolution phase of inflammation: novel endogenous anti-inflammatory and proresolving lipid mediators and pathways. Annu. Rev. Immunol., 25, 101-137.
-
(2007)
Annu. Rev. Immunol.
, vol.25
, pp. 101-137
-
-
Serhan, C.N.1
-
159
-
-
67649172232
-
Cystic fibrosis fatty acid imbalance is linked to ceramide deficiency and corrected by fenretinide
-
Guilbault, C.; Wojewodka, G.; Saeed, Z.; Hajduch, M.; Matouk, E.; De Sanctis, J.B. and Radzioch, D. (2009) Cystic fibrosis fatty acid imbalance is linked to ceramide deficiency and corrected by fenretinide. Am. J. Respir. Cell. Mol. Biol., 41, 100-106.
-
(2009)
Am. J. Respir. Cell. Mol. Biol.
, vol.41
, pp. 100-106
-
-
Guilbault, C.1
Wojewodka, G.2
Saeed, Z.3
Hajduch, M.4
Matouk, E.5
de Sanctis, J.B.6
Radzioch, D.7
-
160
-
-
66149105578
-
Combined blockade of GM-CSF and IL-17 pathways potently suppresses chronic destructive arthritis in a TNF{alpha}independent mouse model
-
Plater-Zyberk, C.; Joosten, L.A.; Helsen, M.M.; Koenders, M.I.; Baeuerle, P.A. and van den Berg, W.B. (2009) Combined blockade of GM-CSF and IL-17 pathways potently suppresses chronic destructive arthritis in a TNF{alpha}independent mouse model. Ann. Rheum. Dis., 68, 721-728.
-
(2009)
Ann. Rheum. Dis.
, vol.68
, pp. 721-728
-
-
Plater-Zyberk, C.1
Joosten, L.A.2
Helsen, M.M.3
Koenders, M.I.4
Baeuerle, P.A.5
van den Berg, W.B.6
-
161
-
-
34147198271
-
GM-CSF neutralisation suppresses inflammation and protects cartilage in acute streptococcal cell wall arthritis of mice
-
Plater-Zyberk, C.; Joosten, L.A.; Helsen, M.M.; Hepp, J.; Baeuerle, P.A. and van den Berg, W.B. (2007) GM-CSF neutralisation suppresses inflammation and protects cartilage in acute streptococcal cell wall arthritis of mice. Ann. Rheum. Dis., 66, 452-457.
-
(2007)
Ann. Rheum. Dis.
, vol.66
, pp. 452-457
-
-
Plater-Zyberk, C.1
Joosten, L.A.2
Helsen, M.M.3
Hepp, J.4
Baeuerle, P.A.5
van den Berg, W.B.6
-
162
-
-
33744821605
-
Chemokine receptors in chronic obstructive pulmonary disease (COPD)
-
Panina, P.; Mariani, M.; D'Ambrosio, D. (2006) Chemokine receptors in chronic obstructive pulmonary disease (COPD). Curr. Drug Targets, 7, 669-674.
-
(2006)
Curr. Drug Targets
, vol.7
, pp. 669-674
-
-
Panina, P.1
Mariani, M.2
D'Ambrosio, D.3
-
163
-
-
33748654201
-
CFTR expression in human neutrophils and the phagolysosomal chlorination defect in cystic fibrosis
-
Painter, R.G.; Valentine, V.G.; Lanson, N.A.Jr.; Leidal, K.; Zhang, Q.; Lombard, G.; Thompson, C.; Viswanathan, A.; Nauseef, W.M.; Wang, G. and Wang, G. (2006) CFTR expression in human neutrophils and the phagolysosomal chlorination defect in cystic fibrosis. Biochemistry, 45, 10260-10269.
-
(2006)
Biochemistry
, vol.45
, pp. 10260-10269
-
-
Painter, R.G.1
Valentine, V.G.2
Lanson Jr., N.A.3
Leidal, K.4
Zhang, Q.5
Lombard, G.6
Thompson, C.7
Viswanathan, A.8
Nauseef, W.M.9
Wang, G.10
Wang, G.11
-
164
-
-
0036222413
-
Hematopoietic stem cells for transplantation
-
Verfaillie, C.M. (2002) Hematopoietic stem cells for transplantation. Nat. Immunol., 3, 314-317.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 314-317
-
-
Verfaillie, C.M.1
-
165
-
-
0037019331
-
Stem-cell competition
-
Orkin, S.H. and Morrison, S.J. (2002) Stem-cell competition. Nature, 418, 25-27.
-
(2002)
Nature
, vol.418
, pp. 25-27
-
-
Orkin, S.H.1
Morrison, S.J.2
-
166
-
-
0030889354
-
Marrow stromal cells as stem cells for nonhematopoietic tissues
-
Prockop, D.J. (1997) Marrow stromal cells as stem cells for nonhematopoietic tissues. Science, 276, 71-74.
-
(1997)
Science
, vol.276
, pp. 71-74
-
-
Prockop, D.J.1
-
167
-
-
0033515827
-
Multilineage potential of adult human mesenchymal stem cells
-
Pittenger, M.F.; Mackay, A.M.; Beck, S.C.; Jaiswal, R.K.; Douglas, R.; Mosca, J.D.; Moorman, M.A.; Simonetti, D.W.; Craig, S. and Marshak, D.R. (1999) Multilineage potential of adult human mesenchymal stem cells. Science, 284, 143-147.
-
(1999)
Science
, vol.284
, pp. 143-147
-
-
Pittenger, M.F.1
Mackay, A.M.2
Beck, S.C.3
Jaiswal, R.K.4
Douglas, R.5
Mosca, J.D.6
Moorman, M.A.7
Simonetti, D.W.8
Craig, S.9
Marshak, D.R.10
-
168
-
-
31944451977
-
Limited restoration of cystic fibrosis lung epithelium in vivo with adult marrow derived cells
-
Loi, R.; Beckett, T.; Goncz, K.K.; Suratt, B.T. and Weiss, D.J. (2006) Limited restoration of cystic fibrosis lung epithelium in vivo with adult marrow derived cells. Am. J. Respir. Crit. Care Med., 173, 171-179.
-
(2006)
Am. J. Respir. Crit. Care Med.
, vol.173
, pp. 171-179
-
-
Loi, R.1
Beckett, T.2
Goncz, K.K.3
Suratt, B.T.4
Weiss, D.J.5
-
169
-
-
33644501073
-
Assessment of cystic fibrosis transmembrane conductance regulator (CFTR) activity in CFTR-null mice after bone marrow transplantation
-
Bruscia, E.M.; Price, J.E.; Cheng, E.-C.; Weiner, S.; Caputo, C.; Ferreira, E.C.; Egan, M.E. and Krause, D.S. (2006) Assessment of cystic fibrosis transmembrane conductance regulator (CFTR) activity in CFTR-null mice after bone marrow transplantation. Proc. Natl. Acad. Sci. USA, 103, 2965-2970.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 2965-2970
-
-
Bruscia, E.M.1
Price, J.E.2
Cheng, E.-C.3
Weiner, S.4
Caputo, C.5
Ferreira, E.C.6
Egan, M.E.7
Krause, D.S.8
-
170
-
-
33749513225
-
Engraftment of donor-derived epithelial cells in multiple organs following bone marrow transplantation into newborn mice
-
Bruscia, E.M.; Ziegler, E.C.; Price, J.E.; Weiner, S.; Egan, M.E. and Krause, D.S. (2006) Engraftment of donor-derived epithelial cells in multiple organs following bone marrow transplantation into newborn mice. Stem Cells, 24, 2299-2308.
-
(2006)
Stem Cells
, vol.24
, pp. 2299-2308
-
-
Bruscia, E.M.1
Ziegler, E.C.2
Price, J.E.3
Weiner, S.4
Egan, M.E.5
Krause, D.S.6
-
171
-
-
19944427214
-
Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: Potential therapy for cystic fibrosis
-
Wang, G.; Bunnell, B.A.; Painter, R.G.; Quiniones, B.C.; Tom, S.; Lanson, N.A.J.; Spees, J.L.; Bertucci, D.; Peister, A.; Weiss, D.J.; Valentine, V.G.; Prockop, D.J. and Kolls, J.K. (2005) Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: potential therapy for cystic fibrosis. Proc. Natl. Acad. Sci. USA, 102, 186-191.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 186-191
-
-
Wang, G.1
Bunnell, B.A.2
Painter, R.G.3
Quiniones, B.C.4
Tom, S.5
Lanson, N.A.J.6
Spees, J.L.7
Bertucci, D.8
Peister, A.9
Weiss, D.J.10
Valentine, V.G.11
Prockop, D.J.12
Kolls, J.K.13
-
172
-
-
37549053263
-
Biochemical heterogeneity of mesenchymal stem cell populations: Clues to their therapeutic efficacy
-
Phinney, D.G. (2007) Biochemical heterogeneity of mesenchymal stem cell populations: clues to their therapeutic efficacy. Cell Cycle, 6, 2884-2889.
-
(2007)
Cell Cycle
, vol.6
, pp. 2884-2889
-
-
Phinney, D.G.1
-
173
-
-
34748845732
-
Angiogenic effects of human multipotent stromal cell conditioned medium activate the PI3K-Akt pathway in hypoxic endothelial cells to inhibit apoptosis, increase survival, and stimulate angiogenesis
-
Hung, S.C.; Pochampally, R.R.; Chen, S.C.; Hsu, S.C. and Prockop, D.J. (2007) Angiogenic effects of human multipotent stromal cell conditioned medium activate the PI3K-Akt pathway in hypoxic endothelial cells to inhibit apoptosis, increase survival, and stimulate angiogenesis. Stem Cells, 25, 2363-2370.
-
(2007)
Stem Cells
, vol.25
, pp. 2363-2370
-
-
Hung, S.C.1
Pochampally, R.R.2
Chen, S.C.3
Hsu, S.C.4
Prockop, D.J.5
-
174
-
-
34447645326
-
Subretinal transplantation of bone marrow mesenchymal stem cells delays retinal degeneration in the RCS rat model of retinal degeneration
-
Inoue, Y.; Iriyama, A.; Ueno, S.; Takahashi, H.; Kondo, M.; Tamaki, Y.; Araie, M. and Yanagi, Y. (2007) Subretinal transplantation of bone marrow mesenchymal stem cells delays retinal degeneration in the RCS rat model of retinal degeneration. Exp. Eye Res., 85, 234-241.
-
(2007)
Exp. Eye Res.
, vol.85
, pp. 234-241
-
-
Inoue, Y.1
Iriyama, A.2
Ueno, S.3
Takahashi, H.4
Kondo, M.5
Tamaki, Y.6
Araie, M.7
Yanagi, Y.8
-
175
-
-
20844440562
-
Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms
-
Togel, F.; Hu, Z.; Weiss, K.; Isaac, J.; Lange, C. and Westenfelder, C. (2005) Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms. Am. J. Physiol. Renal. Physiol., 289, F31-F42.
-
(2005)
Am. J. Physiol. Renal. Physiol.
, vol.289
-
-
Togel, F.1
Hu, Z.2
Weiss, K.3
Isaac, J.4
Lange, C.5
Westenfelder, C.6
-
176
-
-
0037478581
-
Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects
-
Ortiz, L.A.; Gambelli, F.; McBride, C.; Gaupp, D.; Baddoo, M.; Kaminski, N. and Phinney, D.G. (2003) Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects. Proc. Natl. Acad. Sci. USA, 100, 8407-8411.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8407-8411
-
-
Ortiz, L.A.1
Gambelli, F.2
McBride, C.3
Gaupp, D.4
Baddoo, M.5
Kaminski, N.6
Phinney, D.G.7
-
177
-
-
34848853276
-
Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1
-
Mei, S.H.; McCarter, S.D.; Deng, Y.; Parker, C.H.; Liles, W.C. and Stewart, D.J. (2007) Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1. PLoS Med., 4, e269.
-
(2007)
PLoS Med
, vol.4
-
-
Mei, S.H.1
McCarter, S.D.2
Deng, Y.3
Parker, C.H.4
Liles, W.C.5
Stewart, D.J.6
-
178
-
-
34547402979
-
Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury
-
Ortiz, L.A.; Dutreil, M.; Fattman, C.; Pandey, A.C.; Torres, G.; Go, K. and Phinney, D.G. (2007) Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury. Proc. Natl. Acad. Sci. USA, 104, 11002-11007.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 11002-11007
-
-
Ortiz, L.A.1
Dutreil, M.2
Fattman, C.3
Pandey, A.C.4
Torres, G.5
Go, K.6
Phinney, D.G.7
-
179
-
-
34548610480
-
Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin- induced acute lung injury in mice
-
Gupta, N.; Su, X.; Popov, B.; Lee, J.W.; Serikov, V. and Matthay, M.A. (2007) Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin- induced acute lung injury in mice. J. Immunol., 179, 1855-1863.
-
(2007)
J. Immunol.
, vol.179
, pp. 1855-1863
-
-
Gupta, N.1
Su, X.2
Popov, B.3
Lee, J.W.4
Serikov, V.5
Matthay, M.A.6
-
180
-
-
34247645621
-
Mesenchymal stem cells: A new strategy for immunosuppression?
-
Uccelli, A.; Pistoia, V. and Moretta, L. (2007) Mesenchymal stem cells: a new strategy for immunosuppression? Trends Immunol., 28, 219-226.
-
(2007)
Trends Immunol
, vol.28
, pp. 219-226
-
-
Uccelli, A.1
Pistoia, V.2
Moretta, L.3
-
181
-
-
61549139061
-
Macrophages directly contribute to the exaggerated inflammatory response in cystic fibrosis transmembrane conductance regulator-/- mice
-
Bruscia, E.M.; Zhang, P.X.; Ferreira, E.; Caputo, C.; Emerson, J.W.; Tuck, D.; Krause, D.S. and Egan, M.E. (2009) Macrophages directly contribute to the exaggerated inflammatory response in cystic fibrosis transmembrane conductance regulator-/- mice. Am. J. Respir. Cell Mol. Biol., 40, 295-304.
-
(2009)
Am. J. Respir. Cell Mol. Biol.
, vol.40
, pp. 295-304
-
-
Bruscia, E.M.1
Zhang, P.X.2
Ferreira, E.3
Caputo, C.4
Emerson, J.W.5
Tuck, D.6
Krause, D.S.7
Egan, M.E.8
-
182
-
-
0035191223
-
Relationship between Ikappa- Balpha deficiency, NFkappaB activity and interleukin-8 production in CF human airway epithelial cells
-
Tabary, O.; Escotte, S.; Couetil, J.P.; Hubert, D.; Dusser, D.; Puchelle, E. and Jacquot, J. (2001) Relationship between Ikappa- Balpha deficiency, NFkappaB activity and interleukin-8 production in CF human airway epithelial cells. Pflugers Arch., 443 (Suppl 1), S40-S44.
-
(2001)
Pflugers Arch
, vol.443
, Issue.SUPPL. 1
-
-
Tabary, O.1
Escotte, S.2
Couetil, J.P.3
Hubert, D.4
Dusser, D.5
Puchelle, E.6
Jacquot, J.7
-
183
-
-
14944344881
-
NF-κB activation and sustained IL-8 gene expression in primary cultures of cystic fibrosis airway epithelial cells stimulated with Pseudomonas aeruginosa
-
Joseph, T.; Look, D. and Ferkol, T. (2005) NF-κB activation and sustained IL-8 gene expression in primary cultures of cystic fibrosis airway epithelial cells stimulated with Pseudomonas aeruginosa. Am. J. Physiol. Lung Cell. Mol. Physiol., 288, L471-L479.
-
(2005)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.288
-
-
Joseph, T.1
Look, D.2
Ferkol, T.3
-
184
-
-
0033831270
-
Exaggerated activation of nuclear factor-kappaB and altered IkappaBbeta processing in cystic fibrosis bronchial epithelial cells
-
Venkatakrishnan, A.; Stecenko, A.A.; King, G.; Blackwell, T.R.; Brigham, K.L.; Christman, J.W. and Blackwell, T.S. (2000) Exaggerated activation of nuclear factor-kappaB and altered IkappaBbeta processing in cystic fibrosis bronchial epithelial cells. Am. J. Respir. Cell. Mol. Biol., 23, 396-403.
-
(2000)
Am. J. Respir. Cell. Mol. Biol.
, vol.23
, pp. 396-403
-
-
Venkatakrishnan, A.1
Stecenko, A.A.2
King, G.3
Blackwell, T.R.4
Brigham, K.L.5
Christman, J.W.6
Blackwell, T.S.7
|