메뉴 건너뛰기




Volumn 40, Issue 9, 2008, Pages 1703-1715

Airway epithelial cell inflammatory signalling in cystic fibrosis

Author keywords

Airway epithelial cells; Cystic fibrosis; Glucocorticoids; Inflammation; NF B; Oxidative stress; Signalling

Indexed keywords

ANTIINFLAMMATORY AGENT; CHLORIDE CHANNEL; DEXAMETHASONE; GLUCOCORTICOID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; NONSTEROID ANTIINFLAMMATORY AGENT; PREDNISONE; REACTIVE OXYGEN METABOLITE;

EID: 46949105608     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2008.02.002     Document Type: Review
Times cited : (95)

References (143)
  • 3
    • 34347333381 scopus 로고    scopus 로고
    • Molecular targeting of CFTR as a therapeutic approach to cystic fibrosis
    • Amaral M.D., and Kunzelmann K. Molecular targeting of CFTR as a therapeutic approach to cystic fibrosis. Trends Pharmacol. Sci. 28 (2007) 334-341
    • (2007) Trends Pharmacol. Sci. , vol.28 , pp. 334-341
    • Amaral, M.D.1    Kunzelmann, K.2
  • 4
    • 38149091749 scopus 로고    scopus 로고
    • Calcium homeostasis is abnormal in cystic fibrosis airway epithelial cells but is normalized after rescue of F508del-CFTR
    • Antigny F., Norez C., Becq F., and Vandebrouck C. Calcium homeostasis is abnormal in cystic fibrosis airway epithelial cells but is normalized after rescue of F508del-CFTR. Cell Calcium 43 (2008) 175-183
    • (2008) Cell Calcium , vol.43 , pp. 175-183
    • Antigny, F.1    Norez, C.2    Becq, F.3    Vandebrouck, C.4
  • 5
    • 0021970474 scopus 로고
    • Alternate-day prednisone reduces morbidity and improves pulmonary function in cystic fibrosis
    • Auerbach H.S., Williams M., Kirkpatrick J.A., and Colten H.R. Alternate-day prednisone reduces morbidity and improves pulmonary function in cystic fibrosis. Lancet 2 (1985) 686-688
    • (1985) Lancet , vol.2 , pp. 686-688
    • Auerbach, H.S.1    Williams, M.2    Kirkpatrick, J.A.3    Colten, H.R.4
  • 7
    • 33745130682 scopus 로고    scopus 로고
    • Multicenter randomized controlled trial of withdrawal of inhaled corticosteroids in cystic fibrosis
    • Balfour-Lynn I.M., Lees B., Hall P., Phillips G., Khan M., Flather M., et al. Multicenter randomized controlled trial of withdrawal of inhaled corticosteroids in cystic fibrosis. Am. J. Respir. Crit. Care Med. 173 (2006) 1356-1362
    • (2006) Am. J. Respir. Crit. Care Med. , vol.173 , pp. 1356-1362
    • Balfour-Lynn, I.M.1    Lees, B.2    Hall, P.3    Phillips, G.4    Khan, M.5    Flather, M.6
  • 8
    • 0029346937 scopus 로고
    • The relationship between infection and inflammation in the early stages of lung disease from cystic fibrosis
    • Balough K., McCubbin M., Weinberger M., Smits W., Ahrens R., and Fick R. The relationship between infection and inflammation in the early stages of lung disease from cystic fibrosis. Pediatr. Pulmonol. 20 (1995) 63-70
    • (1995) Pediatr. Pulmonol. , vol.20 , pp. 63-70
    • Balough, K.1    McCubbin, M.2    Weinberger, M.3    Smits, W.4    Ahrens, R.5    Fick, R.6
  • 10
    • 33644784718 scopus 로고    scopus 로고
    • Corticosteroids: the drugs to beat
    • Barnes P.J. Corticosteroids: the drugs to beat. Eur. J. Pharmacol. 533 (2006) 2-14
    • (2006) Eur. J. Pharmacol. , vol.533 , pp. 2-14
    • Barnes, P.J.1
  • 12
    • 27644571479 scopus 로고    scopus 로고
    • Down-regulation of the anti-inflammatory protein annexin A1 in cystic fibrosis knock-out mice and patients
    • Bensalem N., Ventura A.P., Vallee B., Lipecka J., Tondelier D., Davezac N., et al. Down-regulation of the anti-inflammatory protein annexin A1 in cystic fibrosis knock-out mice and patients. Mol. Cell. Proteomics 4 (2005) 1591-1601
    • (2005) Mol. Cell. Proteomics , vol.4 , pp. 1591-1601
    • Bensalem, N.1    Ventura, A.P.2    Vallee, B.3    Lipecka, J.4    Tondelier, D.5    Davezac, N.6
  • 13
    • 39049101599 scopus 로고    scopus 로고
    • Oxidative stress induces ERK1/2 signaling in cystic fibrosis lung epithelial cells: potentiel mechanism for excessive IL-8 expression
    • Boncoeur E., Bonvin E., Muselet-Charlier C., Henrion-Caude A., Gruenert D., Clement A., et al. Oxidative stress induces ERK1/2 signaling in cystic fibrosis lung epithelial cells: potentiel mechanism for excessive IL-8 expression. Int. J. Biochem. Cell. Biol. 40 (2008) 432-446
    • (2008) Int. J. Biochem. Cell. Biol. , vol.40 , pp. 432-446
    • Boncoeur, E.1    Bonvin, E.2    Muselet-Charlier, C.3    Henrion-Caude, A.4    Gruenert, D.5    Clement, A.6
  • 14
    • 85119726016 scopus 로고    scopus 로고
    • Boncoeur, E., Roque, T., Bonvin, E., Saint Criq, V., Bonora, M., Clement, A., et al. (2008). Cystic fibrosis transmembrane conductance regulator controls lung proteasomal degradation and NF-kB activity in conditions of oxidative stress. Am. J. Pathol, 172, in press.
    • Boncoeur, E., Roque, T., Bonvin, E., Saint Criq, V., Bonora, M., Clement, A., et al. (2008). Cystic fibrosis transmembrane conductance regulator controls lung proteasomal degradation and NF-kB activity in conditions of oxidative stress. Am. J. Pathol, 172, in press.
  • 15
    • 1942469568 scopus 로고    scopus 로고
    • Ventilatory responses to hypercapnia and hypoxia in conscious cystic fibrosis knockout mice Cftr
    • Bonora M., Bernaudin J.F., Guernier C., and Brahimi-Horn M.C. Ventilatory responses to hypercapnia and hypoxia in conscious cystic fibrosis knockout mice Cftr. Pediatr Res. 55 (2004) 738-746
    • (2004) Pediatr Res. , vol.55 , pp. 738-746
    • Bonora, M.1    Bernaudin, J.F.2    Guernier, C.3    Brahimi-Horn, M.C.4
  • 16
    • 0346505482 scopus 로고    scopus 로고
    • New concepts of the pathogenesis of cystic fibrosis lung disease
    • Boucher R.C. New concepts of the pathogenesis of cystic fibrosis lung disease. Eur. Respir. J. 23 (2004) 146-158
    • (2004) Eur. Respir. J. , vol.23 , pp. 146-158
    • Boucher, R.C.1
  • 17
    • 34047166052 scopus 로고    scopus 로고
    • Airway surface dehydration in cystic fibrosis: pathogenesis and therapy
    • Boucher R.C. Airway surface dehydration in cystic fibrosis: pathogenesis and therapy. Annu. Rev. Med. 58 (2007) 157-170
    • (2007) Annu. Rev. Med. , vol.58 , pp. 157-170
    • Boucher, R.C.1
  • 18
    • 34249662628 scopus 로고    scopus 로고
    • Cystic fibrosis: a disease of vulnerability to airway surface dehydration
    • Boucher R.C. Cystic fibrosis: a disease of vulnerability to airway surface dehydration. Trends Mol. Med. 13 (2007) 231-240
    • (2007) Trends Mol. Med. , vol.13 , pp. 231-240
    • Boucher, R.C.1
  • 20
    • 34548023098 scopus 로고    scopus 로고
    • Non! to non-steroidal anti-inflammatory therapy for inflammatory lung disease in cystic fibrosis (at least at the moment)
    • Bush A., and Davies J. Non! to non-steroidal anti-inflammatory therapy for inflammatory lung disease in cystic fibrosis (at least at the moment). J. Pediatr. 151 (2007) 228-230
    • (2007) J. Pediatr. , vol.151 , pp. 228-230
    • Bush, A.1    Davies, J.2
  • 22
    • 33751580475 scopus 로고    scopus 로고
    • Antioxidants in cystic fibrosis. Conclusions from the CF antioxidant workshop, Bethesda, Maryland, November 11-12, 2003
    • Cantin A.M., White T.B., Cross C.E., Forman H.J., Sokol R.J., and Borowitz D. Antioxidants in cystic fibrosis. Conclusions from the CF antioxidant workshop, Bethesda, Maryland, November 11-12, 2003. Free Radic. Biol. Med. 42 (2007) 15-31
    • (2007) Free Radic. Biol. Med. , vol.42 , pp. 15-31
    • Cantin, A.M.1    White, T.B.2    Cross, C.E.3    Forman, H.J.4    Sokol, R.J.5    Borowitz, D.6
  • 23
  • 24
    • 0025242929 scopus 로고
    • Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis
    • Cheng S.H., Gregory R.J., Marshall J., Paul S., Souza D.W., White G.A., et al. Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis. Cell 63 (1990) 827-834
    • (1990) Cell , vol.63 , pp. 827-834
    • Cheng, S.H.1    Gregory, R.J.2    Marshall, J.3    Paul, S.4    Souza, D.W.5    White, G.A.6
  • 25
    • 1542267080 scopus 로고    scopus 로고
    • State of the Art: Why do the lungs of patients with cystic fibrosis become infected and why can't they clear the infection?
    • Chmiel J.F., and Davis P.B. State of the Art: Why do the lungs of patients with cystic fibrosis become infected and why can't they clear the infection?. Respir. Res. 4 (2003) 8
    • (2003) Respir. Res. , vol.4 , pp. 8
    • Chmiel, J.F.1    Davis, P.B.2
  • 26
    • 24344492706 scopus 로고    scopus 로고
    • Anti-inflammatory medications for cystic fibrosis lung disease: selecting the most appropriate agent
    • Chmiel J.F., and Konstan M.W. Anti-inflammatory medications for cystic fibrosis lung disease: selecting the most appropriate agent. Treat Respir. Med. 4 (2005) 255-273
    • (2005) Treat Respir. Med. , vol.4 , pp. 255-273
    • Chmiel, J.F.1    Konstan, M.W.2
  • 27
    • 0028047286 scopus 로고
    • Relationship of a non-cystic fibrosis transmembrane conductance regulator-mediated chloride conductance to organ-level disease in Cftr(-/-) mice
    • Clarke L.L., Grubb B.R., Yankaskas J.R., Cotton C.U., McKenzie A., and Boucher R.C. Relationship of a non-cystic fibrosis transmembrane conductance regulator-mediated chloride conductance to organ-level disease in Cftr(-/-) mice. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 479-483
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 479-483
    • Clarke, L.L.1    Grubb, B.R.2    Yankaskas, J.R.3    Cotton, C.U.4    McKenzie, A.5    Boucher, R.C.6
  • 28
    • 33749984264 scopus 로고    scopus 로고
    • Long term effects of azithromycin in patients with cystic fibrosis: A double blind, placebo controlled trial
    • Clement A., Tamalet A., Leroux E., Ravilly S., Fauroux B., and Jais J.P. Long term effects of azithromycin in patients with cystic fibrosis: A double blind, placebo controlled trial. Thorax 61 (2006) 895-902
    • (2006) Thorax , vol.61 , pp. 895-902
    • Clement, A.1    Tamalet, A.2    Leroux, E.3    Ravilly, S.4    Fauroux, B.5    Jais, J.P.6
  • 32
    • 33947265925 scopus 로고    scopus 로고
    • A quantitative study of NF-kappaB activation by H2O2: relevance in inflammation and synergy with TNF-alpha
    • de Oliveira-Marques V., Cyrne L., Marinho H.S., and Antunes F. A quantitative study of NF-kappaB activation by H2O2: relevance in inflammation and synergy with TNF-alpha. J. Immunol. 178 (2007) 3893-3902
    • (2007) J. Immunol. , vol.178 , pp. 3893-3902
    • de Oliveira-Marques, V.1    Cyrne, L.2    Marinho, H.S.3    Antunes, F.4
  • 33
    • 84921431053 scopus 로고    scopus 로고
    • Oral non-steroidal anti-inflammatory drug therapy for cystic fibrosis
    • CD001505
    • Dezateux C., and Crighton A. Oral non-steroidal anti-inflammatory drug therapy for cystic fibrosis. Cochrane Database Syst. Rev. (2000) CD001505
    • (2000) Cochrane Database Syst. Rev.
    • Dezateux, C.1    Crighton, A.2
  • 34
    • 0032081281 scopus 로고    scopus 로고
    • Activation of NF-kappaB by adherent Pseudomonas aeruginosa in normal and cystic fibrosis respiratory epithelial cells
    • DiMango E., Ratner A.J., Bryan R., Tabibi S., and Prince A. Activation of NF-kappaB by adherent Pseudomonas aeruginosa in normal and cystic fibrosis respiratory epithelial cells. J. Clin. Invest. 101 (1998) 2598-2605
    • (1998) J. Clin. Invest. , vol.101 , pp. 2598-2605
    • DiMango, E.1    Ratner, A.J.2    Bryan, R.3    Tabibi, S.4    Prince, A.5
  • 35
    • 0028881698 scopus 로고
    • Diverse Pseudomonas aeruginosa gene products stimulate respiratory epithelial cells to produce interleukin-8
    • DiMango E., Zar H.J., Bryan R., and Prince A. Diverse Pseudomonas aeruginosa gene products stimulate respiratory epithelial cells to produce interleukin-8. J. Clin. Invest. 96 (1995) 2204-2210
    • (1995) J. Clin. Invest. , vol.96 , pp. 2204-2210
    • DiMango, E.1    Zar, H.J.2    Bryan, R.3    Prince, A.4
  • 36
    • 23644440630 scopus 로고    scopus 로고
    • Anti-inflammatory therapy in cystic fibrosis
    • Dinwiddie R. Anti-inflammatory therapy in cystic fibrosis. J. Cyst. Fibros. 4 Suppl. 2 (2005) 45-48
    • (2005) J. Cyst. Fibros. , vol.4 , Issue.SUPPL. 2 , pp. 45-48
    • Dinwiddie, R.1
  • 38
    • 1642277855 scopus 로고    scopus 로고
    • Characteristic multiorgan pathology of cystic fibrosis in a long-living cystic fibrosis transmembrane regulator knockout murine model
    • Durie P.R., Kent G., Phillips M.J., and Ackerley C.A. Characteristic multiorgan pathology of cystic fibrosis in a long-living cystic fibrosis transmembrane regulator knockout murine model. Am. J. Pathol. 164 (2004) 1481-1493
    • (2004) Am. J. Pathol. , vol.164 , pp. 1481-1493
    • Durie, P.R.1    Kent, G.2    Phillips, M.J.3    Ackerley, C.A.4
  • 39
    • 0036115199 scopus 로고    scopus 로고
    • Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells
    • Egan M.E., Glockner-Pagel J., Ambrose C., Cahill P.A., Pappoe L., Balamuth N., et al. Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells. Nat. Med. 8 (2002) 485-492
    • (2002) Nat. Med. , vol.8 , pp. 485-492
    • Egan, M.E.1    Glockner-Pagel, J.2    Ambrose, C.3    Cahill, P.A.4    Pappoe, L.5    Balamuth, N.6
  • 40
    • 0035431701 scopus 로고    scopus 로고
    • Control of the proinflammatory state in cystic fibrosis lung epithelial cells by genes from the TNF-alphaR/NFkappaB pathway
    • Eidelman O., Srivastava M., Zhang J., Leighton X., Murtie J., Jozwik C., et al. Control of the proinflammatory state in cystic fibrosis lung epithelial cells by genes from the TNF-alphaR/NFkappaB pathway. Mol. Med. 7 (2001) 523-534
    • (2001) Mol. Med. , vol.7 , pp. 523-534
    • Eidelman, O.1    Srivastava, M.2    Zhang, J.3    Leighton, X.4    Murtie, J.5    Jozwik, C.6
  • 41
    • 0028969594 scopus 로고
    • A multicenter study of alternate-day prednisone therapy in patients with cystic fibrosis. Cystic Fibrosis Foundation Prednisone Trial Group
    • Eigen H., Rosenstein B.J., FitzSimmons S., and Schidlow D.V. A multicenter study of alternate-day prednisone therapy in patients with cystic fibrosis. Cystic Fibrosis Foundation Prednisone Trial Group. J. Pediatr. 126 (1995) 515-523
    • (1995) J. Pediatr. , vol.126 , pp. 515-523
    • Eigen, H.1    Rosenstein, B.J.2    FitzSimmons, S.3    Schidlow, D.V.4
  • 42
    • 30944466084 scopus 로고    scopus 로고
    • A controlled trial of long-term inhaled hypertonic saline in patients with cystic fibrosis
    • Elkins M.R., Robinson M., Rose B.R., Harbour C., Moriarty C.P., Marks G.B., et al. A controlled trial of long-term inhaled hypertonic saline in patients with cystic fibrosis. N. Engl. J. Med. 354 (2006) 229-240
    • (2006) N. Engl. J. Med. , vol.354 , pp. 229-240
    • Elkins, M.R.1    Robinson, M.2    Rose, B.R.3    Harbour, C.4    Moriarty, C.P.5    Marks, G.B.6
  • 43
    • 0037190575 scopus 로고    scopus 로고
    • Long term azithromycin in children with cystic fibrosis: a randomised, placebo-controlled crossover trial
    • Equi A., Balfour-Lynn I.M., Bush A., and Rosenthal M. Long term azithromycin in children with cystic fibrosis: a randomised, placebo-controlled crossover trial. Lancet 360 (2002) 978-984
    • (2002) Lancet , vol.360 , pp. 978-984
    • Equi, A.1    Balfour-Lynn, I.M.2    Bush, A.3    Rosenthal, M.4
  • 46
    • 33750523632 scopus 로고    scopus 로고
    • NF-kappaB activation by reactive oxygen species: fifteen years later
    • Gloire G., Legrand-Poels S., and Piette J. NF-kappaB activation by reactive oxygen species: fifteen years later. Biochem. Pharmacol. 72 (2006) 1493-1505
    • (2006) Biochem. Pharmacol. , vol.72 , pp. 1493-1505
    • Gloire, G.1    Legrand-Poels, S.2    Piette, J.3
  • 47
    • 38349018953 scopus 로고    scopus 로고
    • Airway epithelial cell signaling in response to bacterial pathogens
    • Gomez M.I., and Prince A. Airway epithelial cell signaling in response to bacterial pathogens. Pediatr. Pulmonol. 43 (2008) 11-19
    • (2008) Pediatr. Pulmonol. , vol.43 , pp. 11-19
    • Gomez, M.I.1    Prince, A.2
  • 50
    • 49949151883 scopus 로고    scopus 로고
    • IL-6 and IL-8 increase the expression of glycosyltransferases and sulfotransferases involved in the biosynthesis of sialylated and/or sulfated Lewis x epitopes in the human bronchial mucosa
    • Groux-Degroote S., Krzewinski-Recchi M.A., Cazet A., Vincent A., Lehoux S., Lafitte J.J., et al. IL-6 and IL-8 increase the expression of glycosyltransferases and sulfotransferases involved in the biosynthesis of sialylated and/or sulfated Lewis x epitopes in the human bronchial mucosa. Biochem. J. (2007)
    • (2007) Biochem. J.
    • Groux-Degroote, S.1    Krzewinski-Recchi, M.A.2    Cazet, A.3    Vincent, A.4    Lehoux, S.5    Lafitte, J.J.6
  • 51
    • 0032962320 scopus 로고    scopus 로고
    • Pathophysiology of gene-targeted mouse models for cystic fibrosis
    • Grubb B.R., and Boucher R.C. Pathophysiology of gene-targeted mouse models for cystic fibrosis. Physiol. Rev. 79 (1999) S193-S214
    • (1999) Physiol. Rev. , vol.79
    • Grubb, B.R.1    Boucher, R.C.2
  • 52
    • 11044227865 scopus 로고    scopus 로고
    • Established cell lines used in cystic fibrosis research
    • Gruenert D.C., Willems M., Cassiman J.J., and Frizzell R.A. Established cell lines used in cystic fibrosis research. J. Cyst. Fibros 3 Suppl 2 (2004) 191-196
    • (2004) J. Cyst. Fibros , vol.3 , Issue.SUPPL. 2 , pp. 191-196
    • Gruenert, D.C.1    Willems, M.2    Cassiman, J.J.3    Frizzell, R.A.4
  • 53
    • 33745772850 scopus 로고    scopus 로고
    • New insights into cystic fibrosis: molecular switches that regulate CFTR
    • Guggino W.B., and Stanton B.A. New insights into cystic fibrosis: molecular switches that regulate CFTR. Nat. Rev. Mol. Cell Biol. 7 (2006) 426-436
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 426-436
    • Guggino, W.B.1    Stanton, B.A.2
  • 54
    • 33645231670 scopus 로고    scopus 로고
    • Up-regulation of AMP-activated kinase by dysfunctional cystic fibrosis transmembrane conductance regulator in cystic fibrosis airway epithelial cells mitigates excessive inflammation
    • Hallows K.R., Fitch A.C., Richardson C.A., Reynolds P.R., Clancy J.P., Dagher P.C., et al. Up-regulation of AMP-activated kinase by dysfunctional cystic fibrosis transmembrane conductance regulator in cystic fibrosis airway epithelial cells mitigates excessive inflammation. J. Biol. Chem. 281 (2006) 4231-4241
    • (2006) J. Biol. Chem. , vol.281 , pp. 4231-4241
    • Hallows, K.R.1    Fitch, A.C.2    Richardson, C.A.3    Reynolds, P.R.4    Clancy, J.P.5    Dagher, P.C.6
  • 55
    • 36849020586 scopus 로고    scopus 로고
    • Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease
    • Hartl D., Latzin P., Hordijk P., Marcos V., Rudolph C., Woischnik M., et al. Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease. Nat. Med. 13 (2007) 1423-1430
    • (2007) Nat. Med. , vol.13 , pp. 1423-1430
    • Hartl, D.1    Latzin, P.2    Hordijk, P.3    Marcos, V.4    Rudolph, C.5    Woischnik, M.6
  • 56
    • 0033537767 scopus 로고    scopus 로고
    • Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase
    • Hu Y., Baud V., Delhase M., Zhang P., Deerinck T., Ellisman M., et al. Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase. Science 284 (1999) 316-320
    • (1999) Science , vol.284 , pp. 316-320
    • Hu, Y.1    Baud, V.2    Delhase, M.3    Zhang, P.4    Deerinck, T.5    Ellisman, M.6
  • 57
    • 0035876878 scopus 로고    scopus 로고
    • Rethinking cystic fibrosis pathology: the critical role of abnormal reduced glutathione (GSH) transport caused by CFTR mutation
    • Hudson V.M. Rethinking cystic fibrosis pathology: the critical role of abnormal reduced glutathione (GSH) transport caused by CFTR mutation. Free Radic. Biol. Med. 30 (2001) 1440-1461
    • (2001) Free Radic. Biol. Med. , vol.30 , pp. 1440-1461
    • Hudson, V.M.1
  • 58
    • 12744273488 scopus 로고    scopus 로고
    • New insights into the pathogenesis of cystic fibrosis: pivotal role of glutathione system dysfunction and implications for therapy
    • Hudson V.M. New insights into the pathogenesis of cystic fibrosis: pivotal role of glutathione system dysfunction and implications for therapy. Treat. Respir. Med. 3 (2004) 353-363
    • (2004) Treat. Respir. Med. , vol.3 , pp. 353-363
    • Hudson, V.M.1
  • 59
    • 33947526466 scopus 로고    scopus 로고
    • Mucus secretion by single tracheal submucosal glands from normal and cystic fibrosis transmembrane conductance regulator knockout mice
    • Ianowski J.P., Choi J.Y., Wine J.J., and Hanrahan J.W. Mucus secretion by single tracheal submucosal glands from normal and cystic fibrosis transmembrane conductance regulator knockout mice. J. Physiol. 580 (2007) 301-314
    • (2007) J. Physiol. , vol.580 , pp. 301-314
    • Ianowski, J.P.1    Choi, J.Y.2    Wine, J.J.3    Hanrahan, J.W.4
  • 60
    • 0027402791 scopus 로고
    • Localization of the cystic fibrosis transmembrane conductance regulator in airway secretory glands
    • Jacquot J., Puchelle E., Hinnrasky J., Fuchey C., Bettinger C., Spilmont C., et al. Localization of the cystic fibrosis transmembrane conductance regulator in airway secretory glands. Eur. Respir. J. 6 (1993) 169-176
    • (1993) Eur. Respir. J. , vol.6 , pp. 169-176
    • Jacquot, J.1    Puchelle, E.2    Hinnrasky, J.3    Fuchey, C.4    Bettinger, C.5    Spilmont, C.6
  • 61
    • 0033571379 scopus 로고    scopus 로고
    • Roles of intracellular calcium and NF-kappa B in the Clostridium difficile toxin A-induced up-regulation and secretion of IL-8 from human monocytes
    • Jefferson K.K., Smith Jr. M.F., and Bobak D.A. Roles of intracellular calcium and NF-kappa B in the Clostridium difficile toxin A-induced up-regulation and secretion of IL-8 from human monocytes. J. Immunol. 163 (1999) 5183-5191
    • (1999) J. Immunol. , vol.163 , pp. 5183-5191
    • Jefferson, K.K.1    Smith Jr., M.F.2    Bobak, D.A.3
  • 62
    • 33646348165 scopus 로고    scopus 로고
    • Hyposecretion, not hyperabsorption, is the basic defect of cystic fibrosis airway glands
    • Joo N.S., Irokawa T., Robbins R.C., and Wine J.J. Hyposecretion, not hyperabsorption, is the basic defect of cystic fibrosis airway glands. J. Biol. Chem. 281 (2006) 7392-7398
    • (2006) J. Biol. Chem. , vol.281 , pp. 7392-7398
    • Joo, N.S.1    Irokawa, T.2    Robbins, R.C.3    Wine, J.J.4
  • 63
    • 14044277556 scopus 로고    scopus 로고
    • Redox regulation of NF-kappaB activation: distinct redox regulation between the cytoplasm and the nucleus
    • Kabe Y., Ando K., Hirao S., Yoshida M., and Handa H. Redox regulation of NF-kappaB activation: distinct redox regulation between the cytoplasm and the nucleus. Antioxid. Redox Signal 7 (2005) 395-403
    • (2005) Antioxid. Redox Signal , vol.7 , pp. 395-403
    • Kabe, Y.1    Ando, K.2    Hirao, S.3    Yoshida, M.4    Handa, H.5
  • 64
    • 4644272735 scopus 로고    scopus 로고
    • Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway
    • Karp C.L., Flick L.M., Park K.W., Softic S., Greer T.M., Keledjian R., et al. Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway. Nat. Immunol. 5 (2004) 388-392
    • (2004) Nat. Immunol. , vol.5 , pp. 388-392
    • Karp, C.L.1    Flick, L.M.2    Park, K.W.3    Softic, S.4    Greer, T.M.5    Keledjian, R.6
  • 67
    • 36848999782 scopus 로고    scopus 로고
    • Clinical Use of Ibuprofen is Associated with Slower FEV1 Decline in Children with Cystic Fibrosis
    • Konstan M.W., Schluchter M.D., Xue W., and Davis P.B. Clinical Use of Ibuprofen is Associated with Slower FEV1 Decline in Children with Cystic Fibrosis. Am. J. Respir. Crit. Care Med. (2007)
    • (2007) Am. J. Respir. Crit. Care Med.
    • Konstan, M.W.1    Schluchter, M.D.2    Xue, W.3    Davis, P.B.4
  • 68
    • 18244377969 scopus 로고    scopus 로고
    • Characterization of wild-type and deltaF508 cystic fibrosis transmembrane regulator in human respiratory epithelia
    • Kreda S.M., Mall M., Mengos A., Rochelle L., Yankaskas J., Riordan J.R., et al. Characterization of wild-type and deltaF508 cystic fibrosis transmembrane regulator in human respiratory epithelia. Mol. Biol. Cell 16 (2005) 2154-2167
    • (2005) Mol. Biol. Cell , vol.16 , pp. 2154-2167
    • Kreda, S.M.1    Mall, M.2    Mengos, A.3    Rochelle, L.4    Yankaskas, J.5    Riordan, J.R.6
  • 69
    • 0034997191 scopus 로고    scopus 로고
    • Proinflammatory cytokine responses to P. aeruginosa infection in human airway epithelial cell lines
    • Kube D., Sontich U., Fletcher D., and Davis P.B. Proinflammatory cytokine responses to P. aeruginosa infection in human airway epithelial cell lines. Am. J. Physiol. Lung Cell Mol. Physiol. 280 (2001) L493-L502
    • (2001) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.280
    • Kube, D.1    Sontich, U.2    Fletcher, D.3    Davis, P.B.4
  • 70
    • 35848942405 scopus 로고    scopus 로고
    • Knockdown of NHERF1 enhances degradation of temperature rescued DeltaF508 CFTR from the cell surface of human airway cells
    • Kwon S.H., Pollard H., and Guggino W.B. Knockdown of NHERF1 enhances degradation of temperature rescued DeltaF508 CFTR from the cell surface of human airway cells. Cell Physiol. Biochem. 20 (2007) 763-772
    • (2007) Cell Physiol. Biochem. , vol.20 , pp. 763-772
    • Kwon, S.H.1    Pollard, H.2    Guggino, W.B.3
  • 71
    • 3042548715 scopus 로고    scopus 로고
    • Longitudinal study of oxidative status in 312 cystic fibrosis patients in stable state and during bronchial exacerbation
    • Lagrange-Puget M., Durieu I., Ecochard R., Abbas-Chorfa F., Drai J., Steghens J.P., et al. Longitudinal study of oxidative status in 312 cystic fibrosis patients in stable state and during bronchial exacerbation. Pediatr. Pulmonol. 38 (2004) 43-49
    • (2004) Pediatr. Pulmonol. , vol.38 , pp. 43-49
    • Lagrange-Puget, M.1    Durieu, I.2    Ecochard, R.3    Abbas-Chorfa, F.4    Drai, J.5    Steghens, J.P.6
  • 72
    • 44949151079 scopus 로고    scopus 로고
    • Oral non-steroidal anti-inflammatory drug therapy for cystic fibrosis
    • CD001505
    • Lands L., and Stanojevic S. Oral non-steroidal anti-inflammatory drug therapy for cystic fibrosis. Cochrane Database Syst. Rev. (2007) CD001505
    • (2007) Cochrane Database Syst. Rev.
    • Lands, L.1    Stanojevic, S.2
  • 73
    • 33751177801 scopus 로고    scopus 로고
    • Azithromycin reduces spontaneous and induced inflammation in DeltaF508 cystic fibrosis mice
    • Legssyer R., Huaux F., Lebacq J., Delos M., Marbaix E., Lebecque P., et al. Azithromycin reduces spontaneous and induced inflammation in DeltaF508 cystic fibrosis mice. Respir. Res. 7 (2006) 134
    • (2006) Respir. Res. , vol.7 , pp. 134
    • Legssyer, R.1    Huaux, F.2    Lebacq, J.3    Delos, M.4    Marbaix, E.5    Lebecque, P.6
  • 75
    • 0037383635 scopus 로고    scopus 로고
    • From calcium to NF-kappa B signaling pathways in neurons
    • Lilienbaum A., and Israel A. From calcium to NF-kappa B signaling pathways in neurons. Mol. Cell Biol. 23 (2003) 2680-2698
    • (2003) Mol. Cell Biol. , vol.23 , pp. 2680-2698
    • Lilienbaum, A.1    Israel, A.2
  • 76
    • 0031851457 scopus 로고    scopus 로고
    • Glutathione permeability of CFTR
    • Linsdell P., and Hanrahan J.W. Glutathione permeability of CFTR. Am. J. Physiol. 275 (1998) 323-326
    • (1998) Am. J. Physiol. , vol.275 , pp. 323-326
    • Linsdell, P.1    Hanrahan, J.W.2
  • 77
    • 0035478537 scopus 로고    scopus 로고
    • A real-time electrochemical technique for measurement of cellular hydrogen peroxide generation and consumption: evaluation in human polymorphonuclear leukocytes
    • Liu X., and Zweier J.L. A real-time electrochemical technique for measurement of cellular hydrogen peroxide generation and consumption: evaluation in human polymorphonuclear leukocytes. Free Radic. Biol. Med. 31 (2001) 894-901
    • (2001) Free Radic. Biol. Med. , vol.31 , pp. 894-901
    • Liu, X.1    Zweier, J.L.2
  • 78
    • 33646054284 scopus 로고    scopus 로고
    • Cutting edge: enhanced pulmonary clearance of Pseudomonas aeruginosa by Muc1 knockout mice
    • Lu W., Hisatsune A., Koga T., Kato K., Kuwahara I., Lillehoj E.P., et al. Cutting edge: enhanced pulmonary clearance of Pseudomonas aeruginosa by Muc1 knockout mice. J. Immunol. 176 (2006) 3890-3894
    • (2006) J. Immunol. , vol.176 , pp. 3890-3894
    • Lu, W.1    Hisatsune, A.2    Koga, T.3    Kato, K.4    Kuwahara, I.5    Lillehoj, E.P.6
  • 82
    • 0031992345 scopus 로고    scopus 로고
    • Induction of p21WAF/CIP1 during hyperoxia
    • McGrath S.A. Induction of p21WAF/CIP1 during hyperoxia. Am. J. Respir. Cell Mol. Biol. 18 (1998) 179-187
    • (1998) Am. J. Respir. Cell Mol. Biol. , vol.18 , pp. 179-187
    • McGrath, S.A.1
  • 83
    • 27144514336 scopus 로고    scopus 로고
    • Impact of CFTR DeltaF508 mutation on prostaglandin E2 production and type IIA phospholipase A2 expression by pulmonary epithelial cells
    • Medjane S., Raymond B., Wu Y., and Touqui L. Impact of CFTR DeltaF508 mutation on prostaglandin E2 production and type IIA phospholipase A2 expression by pulmonary epithelial cells. Am. J. Physiol. Lung Cell Mol. Physiol. 289 (2005) L816-L824
    • (2005) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.289
    • Medjane, S.1    Raymond, B.2    Wu, Y.3    Touqui, L.4
  • 87
    • 20144387174 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled, dose-escalating study of aerosolized interferon gamma-1b in patients with mild to moderate cystic fibrosis lung disease
    • Moss R.B., Mayer-Hamblett N., Wagener J., Daines C., Hale K., Ahrens R., et al. Randomized, double-blind, placebo-controlled, dose-escalating study of aerosolized interferon gamma-1b in patients with mild to moderate cystic fibrosis lung disease. Pediatr. Pulmonol. 39 (2005) 209-218
    • (2005) Pediatr. Pulmonol. , vol.39 , pp. 209-218
    • Moss, R.B.1    Mayer-Hamblett, N.2    Wagener, J.3    Daines, C.4    Hale, K.5    Ahrens, R.6
  • 88
    • 33744736979 scopus 로고    scopus 로고
    • Oxidants and signaling by mitogen-activated protein kinases in lung epithelium
    • Mossman B.T., Lounsbury K.M., and Reddy S.P. Oxidants and signaling by mitogen-activated protein kinases in lung epithelium. Am. J. Respir. Cell Mol. Biol. 34 (2006) 666-669
    • (2006) Am. J. Respir. Cell Mol. Biol. , vol.34 , pp. 666-669
    • Mossman, B.T.1    Lounsbury, K.M.2    Reddy, S.P.3
  • 89
    • 0036529082 scopus 로고    scopus 로고
    • Endotoxin activity and inflammatory markers in the airways of young patients with cystic fibrosis
    • Muhlebach M.S., and Noah T.L. Endotoxin activity and inflammatory markers in the airways of young patients with cystic fibrosis. Am. J. Respir. Crit. Care Med. 165 (2002) 911-915
    • (2002) Am. J. Respir. Crit. Care Med. , vol.165 , pp. 911-915
    • Muhlebach, M.S.1    Noah, T.L.2
  • 90
    • 2442581515 scopus 로고    scopus 로고
    • Quantitative cytokine gene expression in CF airway
    • Muhlebach M.S., Reed W., and Noah T.L. Quantitative cytokine gene expression in CF airway. Pediatr. Pulmonol. 37 (2004) 393-399
    • (2004) Pediatr. Pulmonol. , vol.37 , pp. 393-399
    • Muhlebach, M.S.1    Reed, W.2    Noah, T.L.3
  • 91
    • 0032770489 scopus 로고    scopus 로고
    • Quantitation of inflammatory responses to bacteria in young cystic fibrosis and control patients
    • Muhlebach M.S., Stewart P.W., Leigh M.W., and Noah T.L. Quantitation of inflammatory responses to bacteria in young cystic fibrosis and control patients. Am. J. Respir. Crit. Care Med. 160 (1999) 186-191
    • (1999) Am. J. Respir. Crit. Care Med. , vol.160 , pp. 186-191
    • Muhlebach, M.S.1    Stewart, P.W.2    Leigh, M.W.3    Noah, T.L.4
  • 92
    • 49349102821 scopus 로고    scopus 로고
    • Chronic Inflammation in the Cystic Fibrosis Lung: Alterations in Inter- and Intracellular Signaling
    • Nichols D., Chmiel J., and Berger M. Chronic Inflammation in the Cystic Fibrosis Lung: Alterations in Inter- and Intracellular Signaling. Clin. Rev. Allergy Immunol. (2007)
    • (2007) Clin. Rev. Allergy Immunol.
    • Nichols, D.1    Chmiel, J.2    Berger, M.3
  • 93
    • 33645211759 scopus 로고    scopus 로고
    • Rescue of functional delF508-CFTR channels in cystic fibrosis epithelial cells by the alpha-glucosidase inhibitor miglustat
    • Norez C., Noel S., Wilke M., Bijvelds M., Jorna H., Melin P., et al. Rescue of functional delF508-CFTR channels in cystic fibrosis epithelial cells by the alpha-glucosidase inhibitor miglustat. FEBS Lett. 580 (2006) 2081-2086
    • (2006) FEBS Lett. , vol.580 , pp. 2081-2086
    • Norez, C.1    Noel, S.2    Wilke, M.3    Bijvelds, M.4    Jorna, H.5    Melin, P.6
  • 94
    • 36048932954 scopus 로고    scopus 로고
    • Elevated furin levels in human cystic fibrosis cells result in hypersusceptibility to exotoxin A-induced cytotoxicity
    • Ornatowski W., Poschet J.F., Perkett E., Taylor-Cousar J.L., and Deretic V. Elevated furin levels in human cystic fibrosis cells result in hypersusceptibility to exotoxin A-induced cytotoxicity. J. Clin. Invest. 117 (2007) 3489-3497
    • (2007) J. Clin. Invest. , vol.117 , pp. 3489-3497
    • Ornatowski, W.1    Poschet, J.F.2    Perkett, E.3    Taylor-Cousar, J.L.4    Deretic, V.5
  • 95
    • 1342347864 scopus 로고    scopus 로고
    • Alveolar cell death in hyperoxia-induced lung injury
    • Pagano A., and Barazzone-Argiroffo C. Alveolar cell death in hyperoxia-induced lung injury. Ann. NY Acad. Sci. 1010 (2003) 405-416
    • (2003) Ann. NY Acad. Sci. , vol.1010 , pp. 405-416
    • Pagano, A.1    Barazzone-Argiroffo, C.2
  • 97
    • 37449031035 scopus 로고    scopus 로고
    • Circulating and airway neutrophils in cystic fibrosis display different TLR expression and responsiveness to interleukin-10
    • Petit-Bertron A.F., Tabary O., Corvol H., Jacquot J., Clement A., Cavaillon J.M., et al. Circulating and airway neutrophils in cystic fibrosis display different TLR expression and responsiveness to interleukin-10. Cytokine 41 (2008) 54-60
    • (2008) Cytokine , vol.41 , pp. 54-60
    • Petit-Bertron, A.F.1    Tabary, O.2    Corvol, H.3    Jacquot, J.4    Clement, A.5    Cavaillon, J.M.6
  • 100
    • 20044365463 scopus 로고    scopus 로고
    • High abundance protein profiling of cystic fibrosis lung epithelial cells
    • Pollard H.B., Ji X.D., Jozwik C., and Jacobowitz D.M. High abundance protein profiling of cystic fibrosis lung epithelial cells. Proteomics 5 (2005) 2210-2226
    • (2005) Proteomics , vol.5 , pp. 2210-2226
    • Pollard, H.B.1    Ji, X.D.2    Jozwik, C.3    Jacobowitz, D.M.4
  • 101
    • 23244438717 scopus 로고    scopus 로고
    • Oxidative stress in pathogenesis of chronic obstructive pulmonary disease: cellular and molecular mechanisms
    • Rahman I. Oxidative stress in pathogenesis of chronic obstructive pulmonary disease: cellular and molecular mechanisms. Cell Biochem. Biophys. 43 (2005) 167-188
    • (2005) Cell Biochem. Biophys. , vol.43 , pp. 167-188
    • Rahman, I.1
  • 102
    • 13244262601 scopus 로고    scopus 로고
    • Redox signaling in the lungs
    • Rahman I. Redox signaling in the lungs. Antioxid. Redox Signal. 7 (2005) 1-5
    • (2005) Antioxid. Redox Signal. , vol.7 , pp. 1-5
    • Rahman, I.1
  • 103
    • 24744461848 scopus 로고    scopus 로고
    • Inhibition of p38 mitogen activated protein kinase controls airway inflammation in cystic fibrosis
    • Raia V., Maiuri L., Ciacci C., Ricciardelli I., Vacca L., Auricchio S., et al. Inhibition of p38 mitogen activated protein kinase controls airway inflammation in cystic fibrosis. Thorax 60 (2005) 773-780
    • (2005) Thorax , vol.60 , pp. 773-780
    • Raia, V.1    Maiuri, L.2    Ciacci, C.3    Ricciardelli, I.4    Vacca, L.5    Auricchio, S.6
  • 104
    • 33745191871 scopus 로고    scopus 로고
    • What's new in CF airway inflammation: an update
    • Ratjen F. What's new in CF airway inflammation: an update. Paediatr. Respir. Rev. 7 Suppl 1 (2006) S70-S72
    • (2006) Paediatr. Respir. Rev. , vol.7 , Issue.SUPPL. 1
    • Ratjen, F.1
  • 105
    • 0037460729 scopus 로고    scopus 로고
    • Cystic fibrosis
    • Ratjen F., and Doring G. Cystic fibrosis. Lancet 361 (2003) 681-689
    • (2003) Lancet , vol.361 , pp. 681-689
    • Ratjen, F.1    Doring, G.2
  • 106
    • 0035374513 scopus 로고    scopus 로고
    • Cystic fibrosis pathogens activate Ca2+-dependent mitogen-activated protein kinase signaling pathways in airway epithelial cells
    • Ratner A.J., Bryan R., Weber A., Nguyen S., Barnes D., Pitt A., et al. Cystic fibrosis pathogens activate Ca2+-dependent mitogen-activated protein kinase signaling pathways in airway epithelial cells. J. Biol. Chem. 276 (2001) 19267-19275
    • (2001) J. Biol. Chem. , vol.276 , pp. 19267-19275
    • Ratner, A.J.1    Bryan, R.2    Weber, A.3    Nguyen, S.4    Barnes, D.5    Pitt, A.6
  • 107
    • 33845687299 scopus 로고    scopus 로고
    • Oxidative stress and lipid-derived inflammatory mediators during acute exacerbations of cystic fibrosis
    • Reid D.W., Misso N., Aggarwal S., Thompson P.J., and Walters E.H. Oxidative stress and lipid-derived inflammatory mediators during acute exacerbations of cystic fibrosis. Respirology 12 (2007) 63-69
    • (2007) Respirology , vol.12 , pp. 63-69
    • Reid, D.W.1    Misso, N.2    Aggarwal, S.3    Thompson, P.J.4    Walters, E.H.5
  • 108
    • 34147134534 scopus 로고    scopus 로고
    • Resistance to Pseudomonas aeruginosa chronic lung infection requires cystic fibrosis transmembrane conductance regulator-modulated interleukin-1 (IL-1) release and signaling through the IL-1 receptor
    • Reiniger N., Lee M.M., Coleman F.T., Ray C., Golan D.E., and Pier G.B. Resistance to Pseudomonas aeruginosa chronic lung infection requires cystic fibrosis transmembrane conductance regulator-modulated interleukin-1 (IL-1) release and signaling through the IL-1 receptor. Infect. Immun. 75 (2007) 1598-1608
    • (2007) Infect. Immun. , vol.75 , pp. 1598-1608
    • Reiniger, N.1    Lee, M.M.2    Coleman, F.T.3    Ray, C.4    Golan, D.E.5    Pier, G.B.6
  • 109
    • 15444376938 scopus 로고    scopus 로고
    • Cystic fibrosis airway epithelial Ca2+ i signaling: the mechanism for the larger agonist-mediated Ca2+ i signals in human cystic fibrosis airway epithelia
    • Ribeiro C.M., Paradiso A.M., Carew M.A., Shears S.B., and Boucher R.C. Cystic fibrosis airway epithelial Ca2+ i signaling: the mechanism for the larger agonist-mediated Ca2+ i signals in human cystic fibrosis airway epithelia. J. Biol. Chem. 280 (2005) 10202-10209
    • (2005) J. Biol. Chem. , vol.280 , pp. 10202-10209
    • Ribeiro, C.M.1    Paradiso, A.M.2    Carew, M.A.3    Shears, S.B.4    Boucher, R.C.5
  • 111
    • 0032779834 scopus 로고    scopus 로고
    • Glutathione aerosol suppresses lung epithelial surface inflammatory cell-derived oxidants in cystic fibrosis
    • Roum J.H., Borok Z., McElvaney N.G., Grimes G.J., Bokser A.D., Buhl R., et al. Glutathione aerosol suppresses lung epithelial surface inflammatory cell-derived oxidants in cystic fibrosis. J. Appl. Physiol. 87 (1999) 438-443
    • (1999) J. Appl. Physiol. , vol.87 , pp. 438-443
    • Roum, J.H.1    Borok, Z.2    McElvaney, N.G.3    Grimes, G.J.4    Bokser, A.D.5    Buhl, R.6
  • 114
    • 34249892217 scopus 로고    scopus 로고
    • Parthenolide inhibits IkappaB kinase, NF-kappaB activation, and inflammatory response in cystic fibrosis cells and mice
    • Saadane A., Masters S., DiDonato J., Li J., and Berger M. Parthenolide inhibits IkappaB kinase, NF-kappaB activation, and inflammatory response in cystic fibrosis cells and mice. Am. J. Respir. Cell Mol. Biol. 36 (2007) 728-736
    • (2007) Am. J. Respir. Cell Mol. Biol. , vol.36 , pp. 728-736
    • Saadane, A.1    Masters, S.2    DiDonato, J.3    Li, J.4    Berger, M.5
  • 115
    • 3442879853 scopus 로고    scopus 로고
    • Molecular targets for modulating lung inflammation and injury
    • Sadikot R.T., Christman J.W., and Blackwell T.S. Molecular targets for modulating lung inflammation and injury. Curr. Drug Targets 5 (2004) 581-588
    • (2004) Curr. Drug Targets , vol.5 , pp. 581-588
    • Sadikot, R.T.1    Christman, J.W.2    Blackwell, T.S.3
  • 116
    • 34548282581 scopus 로고    scopus 로고
    • Sputum biomarkers of inflammation in cystic fibrosis lung disease
    • Sagel S.D., Chmiel J.F., and Konstan M.W. Sputum biomarkers of inflammation in cystic fibrosis lung disease. Proc. Am. Thorac. Soc. 4 (2007) 406-417
    • (2007) Proc. Am. Thorac. Soc. , vol.4 , pp. 406-417
    • Sagel, S.D.1    Chmiel, J.F.2    Konstan, M.W.3
  • 117
    • 0141816759 scopus 로고    scopus 로고
    • Azithromycin in patients with cystic fibrosis chronically infected with Pseudomonas aeruginosa: a randomized controlled trial
    • Saiman L., Marshall B.C., Mayer-Hamblett N., Burns J.L., Quittner A.L., Cibene D.A., et al. Azithromycin in patients with cystic fibrosis chronically infected with Pseudomonas aeruginosa: a randomized controlled trial. JAMA 290 (2003) 1749-1756
    • (2003) JAMA , vol.290 , pp. 1749-1756
    • Saiman, L.1    Marshall, B.C.2    Mayer-Hamblett, N.3    Burns, J.L.4    Quittner, A.L.5    Cibene, D.A.6
  • 118
    • 0020696950 scopus 로고
    • Chronic Pseudomonas aeruginosa lung infection in cystic fibrosis. A longitudinal study of immune complex activity and inflammatory response in sputum sol-phase of cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infections: influence of local steroid treatment
    • Schiotz P.O., Jorgensen M., Flensborg E.W., Faero O., Husby S., Hoiby N., et al. Chronic Pseudomonas aeruginosa lung infection in cystic fibrosis. A longitudinal study of immune complex activity and inflammatory response in sputum sol-phase of cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infections: influence of local steroid treatment. Acta Paediatr. Scand. 72 (1983) 283-287
    • (1983) Acta Paediatr. Scand. , vol.72 , pp. 283-287
    • Schiotz, P.O.1    Jorgensen, M.2    Flensborg, E.W.3    Faero, O.4    Husby, S.5    Hoiby, N.6
  • 121
    • 4344710449 scopus 로고    scopus 로고
    • NADPH oxidase-dependent acid production in airway epithelial cells
    • Schwarzer C., Machen T.E., Illek B., and Fischer H. NADPH oxidase-dependent acid production in airway epithelial cells. J. Biol. Chem. 279 (2004) 36454-36461
    • (2004) J. Biol. Chem. , vol.279 , pp. 36454-36461
    • Schwarzer, C.1    Machen, T.E.2    Illek, B.3    Fischer, H.4
  • 122
    • 0032912589 scopus 로고    scopus 로고
    • Structure and function of the CFTR chloride channel
    • Sheppard D.N., and Welsh M.J. Structure and function of the CFTR chloride channel. Physiol. Rev. 79 (1999) S23-S45
    • (1999) Physiol. Rev. , vol.79
    • Sheppard, D.N.1    Welsh, M.J.2
  • 124
    • 30944440652 scopus 로고    scopus 로고
    • Protein oxidation by chronic pulmonary diseases in children
    • Starosta V., and Griese M. Protein oxidation by chronic pulmonary diseases in children. Pediatr. Pulmonol. 41 (2006) 67-73
    • (2006) Pediatr. Pulmonol. , vol.41 , pp. 67-73
    • Starosta, V.1    Griese, M.2
  • 125
    • 34247497283 scopus 로고    scopus 로고
    • Cystic fibrosis: A review of epidemiology and pathobiology
    • Strausbaugh S.D., and Davis P.B. Cystic fibrosis: A review of epidemiology and pathobiology. Clin. Chest Med. 28 (2007) 279-288
    • (2007) Clin. Chest Med. , vol.28 , pp. 279-288
    • Strausbaugh, S.D.1    Davis, P.B.2
  • 126
    • 30944432774 scopus 로고    scopus 로고
    • Calcium-dependent regulation of NF-(kappa)B activation in cystic fibrosis airway epithelial cells
    • Tabary O., Boncoeur E., de Martin R., Pepperkok R., Clement A., Schultz C., et al. Calcium-dependent regulation of NF-(kappa)B activation in cystic fibrosis airway epithelial cells. Cell Signal 18 (2006) 652-660
    • (2006) Cell Signal , vol.18 , pp. 652-660
    • Tabary, O.1    Boncoeur, E.2    de Martin, R.3    Pepperkok, R.4    Clement, A.5    Schultz, C.6
  • 128
    • 0032813905 scopus 로고    scopus 로고
    • Genistein inhibits constitutive and inducible NFkappaB activation and decreases IL-8 production by human cystic fibrosis bronchial gland cells
    • Tabary O., Escotte S., Couetil J.P., Hubert D., Dusser D., Puchelle E., et al. Genistein inhibits constitutive and inducible NFkappaB activation and decreases IL-8 production by human cystic fibrosis bronchial gland cells. Am. J. Pathol. 155 (1999) 473-481
    • (1999) Am. J. Pathol. , vol.155 , pp. 473-481
    • Tabary, O.1    Escotte, S.2    Couetil, J.P.3    Hubert, D.4    Dusser, D.5    Puchelle, E.6
  • 129
    • 0034653569 scopus 로고    scopus 로고
    • High susceptibility for cystic fibrosis human airway gland cells to produce IL-8 through the I kappa B kinase alpha pathway in response to extracellular NaCl content
    • Tabary O., Escotte S., Couetil J.P., Hubert D., Dusser D., Puchelle E., et al. High susceptibility for cystic fibrosis human airway gland cells to produce IL-8 through the I kappa B kinase alpha pathway in response to extracellular NaCl content. J. Immunol. 164 (2000) 3377-3384
    • (2000) J. Immunol. , vol.164 , pp. 3377-3384
    • Tabary, O.1    Escotte, S.2    Couetil, J.P.3    Hubert, D.4    Dusser, D.5    Puchelle, E.6
  • 130
    • 0035191223 scopus 로고    scopus 로고
    • Relationship between IkappaBalpha deficiency, NFkappaB activity and interleukin-8 production in CF human airway epithelial cells
    • Tabary O., Escotte S., Couetil J.P., Hubert D., Dusser D., Puchelle E., et al. Relationship between IkappaBalpha deficiency, NFkappaB activity and interleukin-8 production in CF human airway epithelial cells. Pflugers Arch. 443 Suppl 1 (2001) S40-S44
    • (2001) Pflugers Arch. , vol.443 , Issue.SUPPL. 1
    • Tabary, O.1    Escotte, S.2    Couetil, J.P.3    Hubert, D.4    Dusser, D.5    Puchelle, E.6
  • 131
    • 0037223456 scopus 로고    scopus 로고
    • Interleukin-10 inhibits elevated chemokine interleukin-8 and regulated on activation normal T cell expressed and secreted production in cystic fibrosis bronchial epithelial cells by targeting the I(k)B kinase alpha/beta complex
    • Tabary O., Muselet C., Escotte S., Antonicelli F., Hubert D., Dusser D., et al. Interleukin-10 inhibits elevated chemokine interleukin-8 and regulated on activation normal T cell expressed and secreted production in cystic fibrosis bronchial epithelial cells by targeting the I(k)B kinase alpha/beta complex. Am. J. Pathol. 162 (2003) 293-302
    • (2003) Am. J. Pathol. , vol.162 , pp. 293-302
    • Tabary, O.1    Muselet, C.2    Escotte, S.3    Antonicelli, F.4    Hubert, D.5    Dusser, D.6
  • 132
    • 0031659351 scopus 로고    scopus 로고
    • Selective up-regulation of chemokine IL-8 expression in cystic fibrosis bronchial gland cells in vivo and in vitro
    • Tabary O., Zahm J.M., Hinnrasky J., Couetil J.P., Cornillet P., Guenounou M., et al. Selective up-regulation of chemokine IL-8 expression in cystic fibrosis bronchial gland cells in vivo and in vitro. Am. J. Pathol. 153 (1998) 921-930
    • (1998) Am. J. Pathol. , vol.153 , pp. 921-930
    • Tabary, O.1    Zahm, J.M.2    Hinnrasky, J.3    Couetil, J.P.4    Cornillet, P.5    Guenounou, M.6
  • 135
    • 0025852479 scopus 로고
    • Modulation of transcription factor NF-kappa B binding activity by oxidation-reduction in vitro
    • Toledano M.B., and Leonard W.J. Modulation of transcription factor NF-kappa B binding activity by oxidation-reduction in vitro. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 4328-4332
    • (1991) Proc. Natl. Acad. Sci. U.S.A. , vol.88 , pp. 4328-4332
    • Toledano, M.B.1    Leonard, W.J.2
  • 136
    • 33750737798 scopus 로고    scopus 로고
    • Mitochondrial oxidative stress in the lungs of cystic fibrosis transmembrane conductance regulator protein mutant mice
    • Velsor L.W., Kariya C., Kachadourian R., and Day B.J. Mitochondrial oxidative stress in the lungs of cystic fibrosis transmembrane conductance regulator protein mutant mice. Am. J. Respir. Cell Mol. Biol. 35 (2006) 579-586
    • (2006) Am. J. Respir. Cell Mol. Biol. , vol.35 , pp. 579-586
    • Velsor, L.W.1    Kariya, C.2    Kachadourian, R.3    Day, B.J.4
  • 137
  • 142
    • 0032938086 scopus 로고    scopus 로고
    • Priming of blood neutrophils in children with cystic fibrosis: correlation between functional and phenotypic expression of opsonin receptors before and after platelet-activating factor priming
    • Witko-Sarsat V., Halbwachs-Mecarelli L., Sermet-Gaudelus I., Bessou G., Lenoir G., Allen R.C., et al. Priming of blood neutrophils in children with cystic fibrosis: correlation between functional and phenotypic expression of opsonin receptors before and after platelet-activating factor priming. J. Infect. Dis. 179 (1999) 151-162
    • (1999) J. Infect. Dis. , vol.179 , pp. 151-162
    • Witko-Sarsat, V.1    Halbwachs-Mecarelli, L.2    Sermet-Gaudelus, I.3    Bessou, G.4    Lenoir, G.5    Allen, R.C.6
  • 143
    • 4644313798 scopus 로고    scopus 로고
    • Interleukin 8 secretion from monocytes of subjects heterozygous for the deltaF508 cystic fibrosis transmembrane conductance regulator gene mutation is altered
    • Zaman M.M., Gelrud A., Junaidi O., Regan M.M., Warny M., Shea J.C., et al. Interleukin 8 secretion from monocytes of subjects heterozygous for the deltaF508 cystic fibrosis transmembrane conductance regulator gene mutation is altered. Clin. Diagn. Lab. Immunol. 11 (2004) 819-824
    • (2004) Clin. Diagn. Lab. Immunol. , vol.11 , pp. 819-824
    • Zaman, M.M.1    Gelrud, A.2    Junaidi, O.3    Regan, M.M.4    Warny, M.5    Shea, J.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.