-
1
-
-
0016293655
-
Pulmonary alveolar macrophage, defender against bacterial infection of the lung
-
Goldstein E, Lippert W, Warshauer D. Pulmonary alveolar macrophage, defender against bacterial infection of the lung. J Clin Invest 1974;54:519-528.
-
(1974)
J Clin Invest
, vol.54
, pp. 519-528
-
-
Goldstein, E.1
Lippert, W.2
Warshauer, D.3
-
2
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak A, He X, Smirnova I, Liu MY, Van Huffel C, Du X, Birdwell D, Alejos E, Silva M, Galanos C, et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998;282:2085-2088.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Van Huffel, C.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
-
3
-
-
0032133278
-
MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways
-
Medzhitov R, Preston-Hurlburt P, Kopp E, Stadlen A, Chen C, Ghosh S, Janeway CA Jr. MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways. Mol Cell 1998;2:253-258.
-
(1998)
Mol Cell
, vol.2
, pp. 253-258
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Kopp, E.3
Stadlen, A.4
Chen, C.5
Ghosh, S.6
Janeway Jr, C.A.7
-
4
-
-
3142724031
-
Toll-like receptor signalling
-
Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol 2004;4:499-511.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
5
-
-
0037178785
-
IRAK-M is a negative regulator of Toll-like receptor signaling
-
Kobayashi K, Hernandez LD, Galan JE, Janeway CA Jr, Medzhitov R, Flavell RA. IRAK-M is a negative regulator of Toll-like receptor signaling. Cell 2002;110:191-202.
-
(2002)
Cell
, vol.110
, pp. 191-202
-
-
Kobayashi, K.1
Hernandez, L.D.2
Galan, J.E.3
Janeway Jr, C.A.4
Medzhitov, R.5
Flavell, R.A.6
-
6
-
-
20644450101
-
Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105
-
Divanovic S, Trompette A, Atabani SF, Madan R, Golenbock DT, Visintin A, Finberg RW, Tarakhovsky A, Vogel SN, Belkaid Y, et al. Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105. Nat Immunol 2005;6:571-578.
-
(2005)
Nat Immunol
, vol.6
, pp. 571-578
-
-
Divanovic, S.1
Trompette, A.2
Atabani, S.F.3
Madan, R.4
Golenbock, D.T.5
Visintin, A.6
Finberg, R.W.7
Tarakhovsky, A.8
Vogel, S.N.9
Belkaid, Y.10
-
7
-
-
0034748924
-
GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.1
-
Shibata Y, Berclaz PY, Chroneos ZC, Yoshida M, Whitsett JA, Trapnell BC. GM-CSF regulates alveolar macrophage differentiation and innate immunity in the lung through PU.1. Immunity 2001;15:557-567.
-
(2001)
Immunity
, vol.15
, pp. 557-567
-
-
Shibata, Y.1
Berclaz, P.Y.2
Chroneos, Z.C.3
Yoshida, M.4
Whitsett, J.A.5
Trapnell, B.C.6
-
8
-
-
0036893475
-
GM-CSF, via PU.1. regulates alveolar macrophage Fcgamma R-mediated phagocytosis and the IL-18/IFN-gamma-mediated molecular connection between innate and adaptive immunity in the lung
-
Berclaz PY, Shibata Y, Whitsett JA, Trapnell BC. GM-CSF, via PU.1. regulates alveolar macrophage Fcgamma R-mediated phagocytosis and the IL-18/IFN-gamma-mediated molecular connection between innate and adaptive immunity in the lung. Blood 2002;100:4193-4200.
-
(2002)
Blood
, vol.100
, pp. 4193-4200
-
-
Berclaz, P.Y.1
Shibata, Y.2
Whitsett, J.A.3
Trapnell, B.C.4
-
9
-
-
0036884161
-
Endocytic internalization of adenovirus, nonspecific phagocytosis, and cytoskeletal organization are coordinately regulated in alveolar macrophages by GM-CSF and PU.1
-
Berclaz PY, Zsengeller Z, Shibata Y, Otake K, Strasbaugh S, Whitsett JA, Trapnell BC. Endocytic internalization of adenovirus, nonspecific phagocytosis, and cytoskeletal organization are coordinately regulated in alveolar macrophages by GM-CSF and PU.1. J Immunol 2002;169:6332-6342.
-
(2002)
J Immunol
, vol.169
, pp. 6332-6342
-
-
Berclaz, P.Y.1
Zsengeller, Z.2
Shibata, Y.3
Otake, K.4
Strasbaugh, S.5
Whitsett, J.A.6
Trapnell, B.C.7
-
10
-
-
0029967842
-
Surfactant metabolism in transgenic mice after granulocyte macrophage-colony stimulating factor ablation
-
Ikegami M, Ueda T, Hull W, Whitsett JA, Mulligan RC, Dranoff G, Jobe AH. Surfactant metabolism in transgenic mice after granulocyte macrophage-colony stimulating factor ablation. Am J Physiol 1996;270:L650-L658.
-
(1996)
Am J Physiol
, vol.270
-
-
Ikegami, M.1
Ueda, T.2
Hull, W.3
Whitsett, J.A.4
Mulligan, R.C.5
Dranoff, G.6
Jobe, A.H.7
-
11
-
-
0028263504
-
Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis
-
Dranoff G, Crawford AD, Sadelain M, Ream B, Rashid A, Bronson RT, Dickersin GR, Bachurski CJ, Mark El, Whitsett JA, et al. Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis. Science 1994;264:713-716.
-
(1994)
Science
, vol.264
, pp. 713-716
-
-
Dranoff, G.1
Crawford, A.D.2
Sadelain, M.3
Ream, B.4
Rashid, A.5
Bronson, R.T.6
Dickersin, G.R.7
Bachurski, C.J.8
Mark, E.9
Whitsett, J.A.10
-
12
-
-
0028236526
-
Granulocyte/macrophage colony-stimulating fiielor-delicienl mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology
-
Stanley E, Lieschke GJ, Grail D, Metcalf D, Hodgson G, Gall JA, Maher DW, Cebon J, Sinickas V, Dunn AR. Granulocyte/macrophage colony-stimulating fiielor-delicienl mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology. Proc Natl Acad Sci USA 1994;91:5592-5596.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 5592-5596
-
-
Stanley, E.1
Lieschke, G.J.2
Grail, D.3
Metcalf, D.4
Hodgson, G.5
Gall, J.A.6
Maher, D.W.7
Cebon, J.8
Sinickas, V.9
Dunn, A.R.10
-
13
-
-
0033557298
-
GM-CSF-deficient mice are susceptible to pulmonary group B streptococcal infection
-
LeVine AM, Reed JA, Kurak KE, Cianciolo E, Whitsett JA. GM-CSF-deficient mice are susceptible to pulmonary group B streptococcal infection. J Clin Invest 1999;103:563-569.
-
(1999)
J Clin Invest
, vol.103
, pp. 563-569
-
-
LeVine, A.M.1
Reed, J.A.2
Kurak, K.E.3
Cianciolo, E.4
Whitsett, J.A.5
-
14
-
-
0034161743
-
Granulocyte-macrophage colony-stimulating factor in the innate immune response to Pneumocystis carinii pneumonia in mice
-
Paine R III, Preston AM, Wilcoxen S, Jin H, Siu BB, Morris SB, Reed JA, Ross G, Whitsell JA, Beck JM. Granulocyte-macrophage colony-stimulating factor in the innate immune response to Pneumocystis carinii pneumonia in mice. J Immunol 2000;164:2602-2609.
-
(2000)
J Immunol
, vol.164
, pp. 2602-2609
-
-
Paine III, R.1
Preston, A.M.2
Wilcoxen, S.3
Jin, H.4
Siu, B.B.5
Morris, S.B.6
Reed, J.A.7
Ross, G.8
Whitsell, J.A.9
Beck, J.M.10
-
15
-
-
20044379240
-
Disruption of granulocyte macrophage-colony stimulating factor production in the lungs severely affects the ability of mice to control Mycobacterium tuberculosis infection
-
Gonzalez-Juarrero M, Hattle JM, Izzo A, Junqueira-Kipnis AP, Shim TS, Trapnell BC, Cooper AM, Orme IM. Disruption of granulocyte macrophage-colony stimulating factor production in the lungs severely affects the ability of mice to control Mycobacterium tuberculosis infection. J Leukoc Biol 2005;77:914-922.
-
(2005)
J Leukoc Biol
, vol.77
, pp. 914-922
-
-
Gonzalez-Juarrero, M.1
Hattle, J.M.2
Izzo, A.3
Junqueira-Kipnis, A.P.4
Shim, T.S.5
Trapnell, B.C.6
Cooper, A.M.7
Orme, I.M.8
-
16
-
-
0030038425
-
Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF-deficient mice
-
see comments
-
Huffman JA, Hull WM, Dranoff G, Mulligan RC, Whitsett JA. Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF-deficient mice. J Clin Invest 1996;97:649-655. (see comments).
-
(1996)
J Clin Invest
, vol.97
, pp. 649-655
-
-
Huffman, J.A.1
Hull, W.M.2
Dranoff, G.3
Mulligan, R.C.4
Whitsett, J.A.5
-
17
-
-
0032954397
-
Aerosolized GM-CSF ameliorates pulmonary alveolar proteinosis in GM-CSF-deficient mice
-
Reed JA, Ikegami M, Cianciolo ER, Lu W, Cho PS, Hull W, Jobe AH, Whitsett JA. Aerosolized GM-CSF ameliorates pulmonary alveolar proteinosis in GM-CSF-deficient mice. Am J Physiol 1999;276:L556-L563.
-
(1999)
Am J Physiol
, vol.276
-
-
Reed, J.A.1
Ikegami, M.2
Cianciolo, E.R.3
Lu, W.4
Cho, P.S.5
Hull, W.6
Jobe, A.H.7
Whitsett, J.A.8
-
18
-
-
20644438874
-
GM-CSF enhances lung growth and causes alveolar type II epithelial cell hyperplasia in transgenic mice
-
Huffman Reed JA, Rice WR, Zsengeller ZK, Wert SE, Dranoff G, Whitsett JA. GM-CSF enhances lung growth and causes alveolar type II epithelial cell hyperplasia in transgenic mice. Am J Physiol 1997;273:L715-L725.
-
(1997)
Am J Physiol
, vol.273
-
-
Huffman Reed, J.A.1
Rice, W.R.2
Zsengeller, Z.K.3
Wert, S.E.4
Dranoff, G.5
Whitsett, J.A.6
-
19
-
-
0024320061
-
-
Mbawuike IN, Herscowitz HB, MH-S, a murine alveolar macrophage cell line: morphological, cytochemical, and functional characteristics. J Leukoc Biol 1989;46:119-127.
-
Mbawuike IN, Herscowitz HB, MH-S, a murine alveolar macrophage cell line: morphological, cytochemical, and functional characteristics. J Leukoc Biol 1989;46:119-127.
-
-
-
-
20
-
-
0034717335
-
Regulation of B lymphocyte and macrophage development by graded expression of PU.1
-
DeKoter RP, Singh H. Regulation of B lymphocyte and macrophage development by graded expression of PU.1. Science 2000;288:1439-1441.
-
(2000)
Science
, vol.288
, pp. 1439-1441
-
-
DeKoter, R.P.1
Singh, H.2
-
21
-
-
0032505771
-
Nonspecific inflammation inhibits adenovirus-mediated pulmonary gene transfer and expression independent of specific acquired immune responses
-
Otake K, Ennist DL, Harrod K, Trapnell BC. Nonspecific inflammation inhibits adenovirus-mediated pulmonary gene transfer and expression independent of specific acquired immune responses. Hum Gene Ther 1998;9:2207-2222.
-
(1998)
Hum Gene Ther
, vol.9
, pp. 2207-2222
-
-
Otake, K.1
Ennist, D.L.2
Harrod, K.3
Trapnell, B.C.4
-
22
-
-
0032474868
-
The oncoprotein Evi-1 represses TGK-beta signalling by inhibiting Smad3
-
Kurokawa M, Mitani K, Irie K, Matsuyama T, Takahashi T, Chiba S, Yazaki Y, Matsumoto K, Hirai H. The oncoprotein Evi-1 represses TGK-beta signalling by inhibiting Smad3. Nature 1998;394:92-96.
-
(1998)
Nature
, vol.394
, pp. 92-96
-
-
Kurokawa, M.1
Mitani, K.2
Irie, K.3
Matsuyama, T.4
Takahashi, T.5
Chiba, S.6
Yazaki, Y.7
Matsumoto, K.8
Hirai, H.9
-
23
-
-
0031201475
-
Increased tolerance to endotoxin by granulocyte-macrophage colony-stimulating factor-deficient mice
-
Basu S, Dunn AR, Marino MW, Savoia H, Hodgson G, Liesehke GJ, Cebon J. Increased tolerance to endotoxin by granulocyte-macrophage colony-stimulating factor-deficient mice. J Immunol 1997;159:1412-1417.
-
(1997)
J Immunol
, vol.159
, pp. 1412-1417
-
-
Basu, S.1
Dunn, A.R.2
Marino, M.W.3
Savoia, H.4
Hodgson, G.5
Liesehke, G.J.6
Cebon, J.7
-
24
-
-
1642405415
-
Innate immune responses to LPS in mouse lung are suppressed and reversed by neutralization of GM-CSF via repression of TLR-4
-
Bozinovski S, Jones J, Beuvitt SJ, Cook AD, Hamilton JA, Anderson GP. Innate immune responses to LPS in mouse lung are suppressed and reversed by neutralization of GM-CSF via repression of TLR-4. Am J Physiol Lung Cell Mol Physiol 2004;286:L877-L885.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.286
-
-
Bozinovski, S.1
Jones, J.2
Beuvitt, S.J.3
Cook, A.D.4
Hamilton, J.A.5
Anderson, G.P.6
-
25
-
-
0030838839
-
Mice lacking both granulocyte colony-stimulating factor (CSF) and granulocyte-macrophage CSF have impaired reproductive capacity, perturbed neonatal granulopoiesis, lung disease, amyloidosis, and reduced long-lerm survival
-
Seymour JF, Lieschke GJ, Grail D, Quilici C, Hodgson G, Dunn AR. Mice lacking both granulocyte colony-stimulating factor (CSF) and granulocyte-macrophage CSF have impaired reproductive capacity, perturbed neonatal granulopoiesis, lung disease, amyloidosis, and reduced long-lerm survival. Blood 1997;90:3037-3049.
-
(1997)
Blood
, vol.90
, pp. 3037-3049
-
-
Seymour, J.F.1
Lieschke, G.J.2
Grail, D.3
Quilici, C.4
Hodgson, G.5
Dunn, A.R.6
-
26
-
-
0036201268
-
GM-CSF regulates pulmonary surfactant ho meostasis and alveolar macrophage-mediated innate host defense
-
Trapnell BC, Whitsett JA. GM-CSF regulates pulmonary surfactant ho meostasis and alveolar macrophage-mediated innate host defense. Annu Rev Physiol 2002;64:775-802.
-
(2002)
Annu Rev Physiol
, vol.64
, pp. 775-802
-
-
Trapnell, B.C.1
Whitsett, J.A.2
-
28
-
-
9144247674
-
High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis
-
Uchida K, Nakata K, Trapnell BC, Terakawa T, Hamano E, Mikami A, Matsushita I, Seymour JF, Oh-Eda M, Ishige I, et al. High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis. Blood 2004;103:1089-1098.
-
(2004)
Blood
, vol.103
, pp. 1089-1098
-
-
Uchida, K.1
Nakata, K.2
Trapnell, B.C.3
Terakawa, T.4
Hamano, E.5
Mikami, A.6
Matsushita, I.7
Seymour, J.F.8
Oh-Eda, M.9
Ishige, I.10
-
29
-
-
0037099251
-
Pulmonary alveolar proteinosis: Progress in the first 44 years
-
Seymour JF, Presneill JJ. Pulmonary alveolar proteinosis: progress in the first 44 years. Am J Respir Crit Care Med 2002;166:215-235.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. 215-235
-
-
Seymour, J.F.1
Presneill, J.J.2
-
31
-
-
0018650296
-
Pulmonary alveolar proteinosis: Abnormal in vitro function of alveolar macrophages
-
Harris JO. Pulmonary alveolar proteinosis: abnormal in vitro function of alveolar macrophages. Chest 1979;76:156-159.
-
(1979)
Chest
, vol.76
, pp. 156-159
-
-
Harris, J.O.1
-
32
-
-
0020531471
-
Macrophage function in pulmonary alveolar proteinosis
-
Nugent KM, Pesanli BL. Macrophage function in pulmonary alveolar proteinosis. Am Rev Respir Dis 1983;127:780-781.
-
(1983)
Am Rev Respir Dis
, vol.127
, pp. 780-781
-
-
Nugent, K.M.1
Pesanli, B.L.2
-
33
-
-
0023022231
-
Pulmonary alveolar proteinosis: Further evaluation of abnormal alveolar macrophages
-
Gonzalez-Rothi RJ, Harris JO. Pulmonary alveolar proteinosis: further evaluation of abnormal alveolar macrophages. Chest 1986;90:656-661.
-
(1986)
Chest
, vol.90
, pp. 656-661
-
-
Gonzalez-Rothi, R.J.1
Harris, J.O.2
-
34
-
-
0142181976
-
-
Bonfield TL, Raychaudhuri B, Malur A, Abraham S. Trapnell BC, Kavuru MS, Thomassen MJ. PU.1 regulation of human alveolar macrophage differentiation requires granulocyte-macrophage colony-stimulating factor. Am J Physiol Lung Cell Mol Physiol 2003;285: L1132-L1136.
-
Bonfield TL, Raychaudhuri B, Malur A, Abraham S. Trapnell BC, Kavuru MS, Thomassen MJ. PU.1 regulation of human alveolar macrophage differentiation requires granulocyte-macrophage colony-stimulating factor. Am J Physiol Lung Cell Mol Physiol 2003;285: L1132-L1136.
-
-
-
-
35
-
-
0036846144
-
Bacterial stimulation of epithelial G-CSF and GM-CSF expression promotes PMN survival in CF airways
-
Saba S, Soong G, Greenberg S, Prince A. Bacterial stimulation of epithelial G-CSF and GM-CSF expression promotes PMN survival in CF airways. Am J Respir Cell Mol Biol 2002;27:561-567.
-
(2002)
Am J Respir Cell Mol Biol
, vol.27
, pp. 561-567
-
-
Saba, S.1
Soong, G.2
Greenberg, S.3
Prince, A.4
-
36
-
-
0034703072
-
CD14-dependent lipopolysaccharide-induced beta-defensin-2 expression in human tracheobronchial epithelium
-
Becker MN, Diamond G, Verghese MW, Randell SH. CD14-dependent lipopolysaccharide-induced beta-defensin-2 expression in human tracheobronchial epithelium. J Biol Chem 2000;275:29731-29736.
-
(2000)
J Biol Chem
, vol.275
, pp. 29731-29736
-
-
Becker, M.N.1
Diamond, G.2
Verghese, M.W.3
Randell, S.H.4
-
37
-
-
0028979682
-
Requirement of MIP-1 alpha for an inflammatory response to viral infection
-
Cook DN, Beck MA, Coffman TM, Kirby SL, Sheridan JF, Pragnell IB. Smithies O. Requirement of MIP-1 alpha for an inflammatory response to viral infection. Science 1996;269:1583-1585.
-
(1996)
Science
, vol.269
, pp. 1583-1585
-
-
Cook, D.N.1
Beck, M.A.2
Coffman, T.M.3
Kirby, S.L.4
Sheridan, J.F.5
Pragnell, I.B.6
Smithies, O.7
-
38
-
-
0029061668
-
Role of macrophage inflammatory protein-1 alpha (MIP-1 alpha) in acute lung injury in rats
-
Shanley TP, Schmal H, Friedl HP, Jones ML, Ward PA. Role of macrophage inflammatory protein-1 alpha (MIP-1 alpha) in acute lung injury in rats. J Immunol 1995;154:4793-4802.
-
(1995)
J Immunol
, vol.154
, pp. 4793-4802
-
-
Shanley, T.P.1
Schmal, H.2
Friedl, H.P.3
Jones, M.L.4
Ward, P.A.5
-
39
-
-
0002958069
-
Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state
-
Hume DA, Underhill DM, Sweet MJ, Ozinsky AO, Liew FY, Aderem A. Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state. BMC Immunol 2001;2:11.
-
(2001)
BMC Immunol
, vol.2
, pp. 11
-
-
Hume, D.A.1
Underhill, D.M.2
Sweet, M.J.3
Ozinsky, A.O.4
Liew, F.Y.5
Aderem, A.6
|