Alterations in ceramide concentration and pH determine the release of reactive oxygen species by Cftr-deficient macrophages on infection

Journal of Immunology

Volumn 184, Issue 9, 2010, Pages 5104-5111

  Zhang, Yang ^a   Li, Xiang ^a   Grassmé, Heike ^a   Döring, Gerd ^b   Gulbins, Erich ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE; CYTOKINE; GLYCOPROTEIN GP 91; REACTIVE OXYGEN METABOLITE; SPHINGOMYELIN PHOSPHODIESTERASE; TRANSMEMBRANE CONDUCTANCE REGULATOR; DEXTRAN; DEXTRAN TETRAMETHYLRHODAMINE; FLUORESCENT DYE; RHODAMINE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; CYTOKINE RELEASE; ENZYME ACTIVATION; EPITHELIUM CELL; LUNG ALVEOLUS EPITHELIUM; LUNG ALVEOLUS MACROPHAGE; MOUSE; NONHUMAN; PH; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTION; WILD TYPE; ANIMAL; BACTERICIDAL ACTIVITY; C57BL MOUSE; CELL CULTURE; CHEMISTRY; COMPARATIVE STUDY; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR MOUSE; DRUG ANTAGONISM; ENZYMOLOGY; FLUORESCENCE MICROSCOPY; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MOUSE MUTANT; PHYSIOLOGY; SECRETION; STAINING; TRANSGENIC MOUSE;

ANIMALS; CELLS, CULTURED; CERAMIDES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DEXTRANS; FLUORESCENT DYES; HYDROGEN-ION CONCENTRATION; MACROPHAGES, ALVEOLAR; MICE; MICE, INBRED C57BL; MICE, INBRED CFTR; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; PSEUDOMONAS AERUGINOSA; REACTIVE OXYGEN SPECIES; RHODAMINES; SERUM BACTERICIDAL TEST; SPHINGOMYELIN PHOSPHODIESTERASE; STAINING AND LABELING;

EID: 77954504913     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0902851     Document Type: Article

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