Telomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongation

Journal of Biological Chemistry

Volumn 286, Issue 5, 2011, Pages 3894-3906

  Soohoo, Christina Y ^a   Shi, Rong ^a,b   Lee, Tae Ho ^a   Huang, Pengyu ^a   Lu, Kun Ping ^a   Zhou, Xiao Zhen ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID RESIDUES; AMINO ACID SEQUENCE; CATALYTIC ACTIVITY; CRITICAL LINKS; FUNCTIONAL DOMAINS; HOMOLOGY DOMAIN; HUMAN TELOMERASE; HYDROPHILIC AND HYDROPHOBIC INTERACTIONS; IN-CELL; TELOMERASE; TELOMERASE ACTIVITY; TELOMERE LENGTH; TELOMERE MAINTENANCE; TELOMERES;

AMINO ACIDS; CATALYST ACTIVITY; ELONGATION; HYDROPHOBICITY; MAINTENANCE; PROTEINS;

CHROMOSOMES;

PROTEIN PINX1; TELOMERASE; TELOMERASE INHIBITOR; TELOMERIC REPEAT BINDING FACTOR 1; UNCLASSIFIED DRUG; AMINO ACID; PINX1 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CHROMOSOMES AND CHROMOSOMAL PHENOMENA; CONTROLLED STUDY; ENZYME ACTIVITY; GENE SILENCING; HOMEOSTASIS; HUMAN; HUMAN CELL; HYDROPHILICITY; HYDROPHOBICITY; METABOLIC REGULATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; TELOMERE ELONGATION; BINDING SITE; DRUG ANTAGONISM; METABOLISM; PROTEIN BINDING; PROTEIN TRANSPORT; TELOMERE;

AMINO ACIDS; BINDING SITES; HOMEOSTASIS; HUMANS; PROTEIN BINDING; PROTEIN TRANSPORT; TELOMERASE; TELOMERE; TELOMERIC REPEAT BINDING PROTEIN 1; TUMOR SUPPRESSOR PROTEINS;

EID: 79952809386     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.180174     Document Type: Article

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