Over-expression of LPTS-L in hepatocellular carcinoma cell line SMMC-7721 induces crisis

World Journal of Gastroenterology

Volumn 8, Issue 6, 2002, Pages 1050-1052

  Liao, Cheng ^a   Zhao, Mu Jun ^a   Zhao, Jing ^a   Jia, Di ^a   Song, Hai ^a   Li, Zai Ping ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE DERIVATIVE; HYBRID PROTEIN; TELOMERASE;

ARTICLE; ASSAY; CANCER CELL CULTURE; CLONE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ESCHERICHIA COLI; GENE CONSTRUCT; GENE FUNCTION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HEPATOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL CARCINOMA; LIVER RELATED PUTATIVE TUMOR SUPPRESSOR GENE; PHENOTYPE; PROTEIN EXPRESSION; TELOMERE; TELOMERIC REPEAT AMPLIFICATION PROTOCOL; TUMOR SUPPRESSOR GENE;

EID: 0036898057     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v8.i6.1050     Document Type: Article

References (18)

1. Blackburn EH. Structure and function of telomeres. Nature 1991; 350: 569-573
2. n, present at the telomeres of human chromosomes. Proc Natl Acad Sci USA 1988; 85: 6622-6626
3. Blackburn EH. Telomeres: Structure and synthesis. J Biol Chem 1990; 265: 5919-5921
4. Blackburn EH. Switching and signaling at the telomere. Cell 2001; 106: 661-673
5. Greider W, Blackburn EH. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 1985; 43: 405-413
6. Nugent CI, Lundblad V. The telomerase reverse transcriptase: Components and regulation. Genes Dev 1998; 12: 1073-1085
7. Feng J, Funk WD, Wang SS, Weinrich SL, Avilion AA, Chiu CP, Adams RR, Chang E, Allsopp RC, Yu J. The RNA component of human telomerase. Science 1995; 269: 1236-1241
8. Shay JW, Zou Y, Hiyama E, Wright WE. Telomerase and cancer. Hum Mol Genet 2001; 10: 677-685
9. Stewart SA, Weinberg RA. Telomerase and human tumorigenesis. Semin Cancer Biol 2000; 10: 399-406
10. Meyerson M. Role of telomerase in normal and cancer cells. J Clin Oncol 2000; 18: 2626-2634
11. Liao C, Zhao M, Song H, Uchida K, Yokoyama KK, Li T. Identification of the gene for a novel liver-related putative tumor suppressor at a high-frequency loss of heterozygosity region of chromosome 8p23 in human hepatocellular carcinoma. Hepatology 2000; 32: 721-727
12. Zhou XZ, Lu KP. The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor. Cell 2001; 107: 347-359
13. Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PL, Coviello GM, Wright WE, Weinrich SL, Shay JW. Specific association of human telomerase activity with immortal cells and cancer. Science 1994; 266: 2011-2015
14. Miuia N, Horikawa I, Nishimoto A, Ohmura H, Ito H, Hirohashi S, Shay JW, Oshimura M. Progressive telomere shortening and telomerase reactivation during hepatocellular carcinogenesis. Cancer Genet Cytogenet 1997; 93: 56-62
15. Huang GT, Lee HS, Chen CH, Chiou LL, Lin YW, Lee CZ, Chen DS, Sheu JC. Telomerase activity and telomere length in human hepatocellular carcinoma. Eur J Cancer 1998; 34: 1946-1949
16. Erlitzki R, Minuk GY. Telomeres, telomerase and HCC: The long and the short of it. J Hepatol 1999; 31: 939-945
17. Zhang FX, Zhang XY, Fan DM, Deng ZY, Yan Y, Wu HP, Fan JJ. Antisense telomerase RNA induced human gastric cancer cell apoptosis. World J Gastroenterol 2000; 6: 430-432
18. Yakoob J, Hu GL, Fan XG, Zhang Z. Telomere, telomerase and digestive cancer. World J Gastroenterol 1999; 5: 334-337