Effect of metal chelators on γ-secretase indicates that calcium and magnesium ions facilitate cleavage of Alzheimer amyloid precursor substrate

International Journal of Alzheimer's Disease

Volumn , Issue , 2011, Pages

  Evin, Geneviéve ^a   Ho, Michael ^a,b   Hoke, David E ^a   Chua, Yee Jia ^a   Li, Qiao Xin ^a   Culvenor, Janetta G ^a   Masters, Colin ^a   White, Anthony R ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; CALCIUM ION; CHELATING AGENT; CLIOQUINOL; EDETIC ACID; EGTAZIC ACID; GAMMA SECRETASE; MAGNESIUM ION; METALLOPROTEINASE INHIBITOR; PHENANTHROLINE; PHOSPHORAMIDON; PRESENILIN 1;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; GEL ELECTROPHORESIS; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; NEUROBLASTOMA; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CLEAVAGE; WESTERN BLOTTING;

EID: 79952170352     PISSN: None     EISSN: 20900252     Source Type: Journal    
DOI: 10.4061/2011/950932     Document Type: Article

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