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Volumn 6, Issue , 2011, Pages 95-119

Mouse models of cancer

Author keywords

cancer gene discovery; gene targeting; genetically engineered mice; oncogene; oncogenomics; tumor suppressor gene

Indexed keywords

BIOLOGICAL MARKER; ETHYLNITROSOUREA; GENE PRODUCT; TUMOR MARKER;

EID: 79751514764     PISSN: 15534006     EISSN: 15534014     Source Type: Book Series    
DOI: 10.1146/annurev.pathol.3.121806.154244     Document Type: Article
Times cited : (277)

References (143)
  • 1
    • 0021720781 scopus 로고
    • Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes
    • Stewart TA, Pattengale PK, Leder P. 1984. Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MT (Pubitemid 15176093)
    • (1984) Cell , vol.38 , Issue.3 , pp. 627-637
    • Stewart, T.A.1    Pattengale, P.K.2    Leder, P.3
  • 2
    • 0021183267 scopus 로고
    • Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors
    • Brinster RL, ChenHY, Messing A, vanDyke T, Levine AJ, et al. 1984. Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors. Cell 37:367-79 (Pubitemid 14079032)
    • (1984) Cell , vol.37 , Issue.2 , pp. 367-379
    • Brinster, R.L.1    Chen, H.Y.2    Messing, A.3
  • 3
    • 0021888904 scopus 로고
    • Heritable formation of pancreatic β-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes
    • DOI 10.1038/315115a0
    • Hanahan D. 1985. Heritable formation of pancreatic â-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes. Nature 315:115-22 (Pubitemid 15064530)
    • (1985) Nature , vol.315 , Issue.6015 , pp. 115-122
    • Hanahan, D.1
  • 4
    • 0022380768 scopus 로고
    • The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice
    • DOI 10.1038/318533a0
    • Adams JM, Harris AW, Pinkert CA, Corcoran LM, Alexander WS, et al. 1985. The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenicmice. Nature 318:533-38 (Pubitemid 16173038)
    • (1985) Nature , vol.318 , Issue.6046 , pp. 533-538
    • Adams, J.M.1    Harris, A.W.2    Pinkert, C.A.3
  • 5
    • 0023646810 scopus 로고
    • Site-directedmutagenesis by gene targeting inmouse embryo-derived stem cells
    • Thomas KR,CapecchiMR. 1987. Site-directedmutagenesis by gene targeting inmouse embryo-derived stem cells. Cell 51:503-12
    • (1987) Cell , vol.51 , pp. 503-512
    • Thomas, K.R.1    Capecchi, M.R.2
  • 6
    • 34548217651 scopus 로고    scopus 로고
    • Maximizing mouse cancer models
    • DOI 10.1038/nrc2192, PII NRC2192
    • Frese KK, Tuveson DA. 2007. Maximizing mouse cancer models. Nat. Rev. Cancer 7:645-58 (Pubitemid 47327410)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.9 , pp. 645-658
    • Frese, K.K.1    Tuveson, D.A.2
  • 7
    • 70350555815 scopus 로고    scopus 로고
    • Germline modification strategies
    • ed. EC Holland, New York: Wiley
    • Grisendi S, Pandolfi PP. 2004. Germline modification strategies. In Mouse Models of Human Cancer, ed. EC Holland, pp. 43-63. New York: Wiley
    • (2004) Mouse Models of Human Cancer , pp. 43-63
    • Grisendi, S.1    Pandolfi, P.P.2
  • 9
    • 0034696399 scopus 로고    scopus 로고
    • Transforming growth factor alpha- and c-myc-induced mammary carcinogenesis in transgenic mice
    • Rose-Hellekant TA, Sandgren EP. 2000. Transforming growth factor á- and c-myc-induced mammary carcinogenesis in transgenic mice. Oncogene 19:1092-96 (Pubitemid 30153795)
    • (2000) Oncogene , vol.19 , Issue.8 , pp. 1092-1096
    • Rose-Hellekant, T.A.1    Sandgren, E.P.2
  • 10
    • 67650383818 scopus 로고    scopus 로고
    • MMTV mouse models and the diagnostic values of MMTV-like sequences in human breast cancer
    • Taneja P, Frazier DP, Kendig RD, Maglic D, Sugiyama T, et al. 2009. MMTV mouse models and the diagnostic values of MMTV-like sequences in human breast cancer. Expert Rev. Mol. Diagn. 9:423-40
    • (2009) Expert Rev. Mol. Diagn. , vol.9 , pp. 423-440
    • Taneja, P.1    Frazier, D.P.2    Kendig, R.D.3    Maglic, D.4    Sugiyama, T.5
  • 11
    • 0026021366 scopus 로고
    • Carcinogen-induced lymphomagenesis in pim-1 transgenic mice: Dose dependence and involvement of myc and ras
    • Breuer M, Wientjens E, Verbeek S, Slebos R, Berns A. 1991. Carcinogen-induced lymphomagenesis in pim-1 transgenic mice: dose dependence and involvement of myc and ras. Cancer Res. 51:958-63
    • (1991) Cancer Res , vol.51 , pp. 958-963
    • Breuer, M.1    Wientjens, E.2    Verbeek, S.3    Slebos, R.4    Berns, A.5
  • 12
    • 0024595556 scopus 로고
    • Predisposition to lymphomagenesis in pim-1 transgenic mice: Cooperation with c-myc and N-myc in murine leukemia virus-induced tumors
    • DOI 10.1016/0092-8674(89)90589-8
    • van LohuizenM, Verbeek S, Krimpenfort P,Domen J, Saris C, et al. 1989. Predisposition to lymphomagenesis in pim-1 transgenic mice: cooperation with c-myc and N-myc in murine leukemia virus-induced tumors. Cell 56:673-82 (Pubitemid 19065532)
    • (1989) Cell , vol.56 , Issue.4 , pp. 673-682
    • Van Lohuizen, M.1    Verbeek, S.2    Krimpenfort, P.3    Domen, J.4    Saris, C.5    Radaszkiewicz, T.6    Berns, A.7
  • 13
    • 0036468677 scopus 로고    scopus 로고
    • Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors
    • DOI 10.1126/science.1067081
    • Lois C, Hong EJ, Pease S, Brown EJ, Baltimore D. 2002. Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors. Science 295:868-72 (Pubitemid 34118370)
    • (2002) Science , vol.295 , Issue.5556 , pp. 868-872
    • Lois, C.1    Hong, E.J.2    Pease, S.3    Brown, E.J.4    Baltimore, D.5
  • 14
    • 0034488835 scopus 로고    scopus 로고
    • Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision
    • Novak A, Guo C, Yang W, Nagy A, Lobe CG. 2000. Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision. Genesis 28:147-55
    • (2000) Genesis , vol.28 , pp. 147-155
    • Novak, A.1    Guo, C.2    Yang, W.3    Nagy, A.4    Lobe, C.G.5
  • 15
    • 0036467996 scopus 로고    scopus 로고
    • Insulators: Many functions, many mechanisms
    • DOI 10.1101/gad.954702
    • West AG, Gaszner M, Felsenfeld G. 2002. Insulators: many functions, many mechanisms. Genes Dev. 16:271-88 (Pubitemid 34111407)
    • (2002) Genes and Development , vol.16 , Issue.3 , pp. 271-288
    • West, A.G.1    Gaszner, M.2    Felsenfeld, G.3
  • 16
    • 32344453096 scopus 로고    scopus 로고
    • Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells
    • DOI 10.1002/gene.20180
    • Beard C, Hochedlinger K, Plath K,Wutz A, Jaenisch R. 2006. Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells. Genesis 44:23-28 (Pubitemid 43222207)
    • (2006) Genesis , vol.44 , Issue.1 , pp. 23-28
    • Beard, C.1    Hochedlinger, K.2    Plath, K.3    Wutz, A.4    Jaenisch, R.5
  • 17
    • 50849133226 scopus 로고    scopus 로고
    • Conditional activation of a single-copy L1 transgene in mice by Cre
    • An W, Han JS, Schrum CM, Maitra A, Koentgen F, et al. 2008. Conditional activation of a single-copy L1 transgene in mice by Cre. Genesis 46:373-83
    • (2008) Genesis , vol.46 , pp. 373-383
    • An, W.1    Han, J.S.2    Schrum, C.M.3    Maitra, A.4    Koentgen, F.5
  • 20
    • 0026561121 scopus 로고
    • Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
    • Donehower LA, Harvey M, Slagle BL, McArthur MJ, Montgomery CA Jr, et al. 1992. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356:215-21
    • (1992) Nature , vol.356 , pp. 215-221
    • Donehower, L.A.1    Harvey, M.2    Slagle, B.L.3    McArthur, M.J.4    Montgomery Jr., C.A.5
  • 22
    • 0030051903 scopus 로고    scopus 로고
    • Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities
    • DOI 10.1038/ng0296-191
    • Gowen LC, Johnson BL, Latour AM, Sulik KK, Koller BH. 1996. Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities. Nat. Genet. 12:191-94 (Pubitemid 26051301)
    • (1996) Nature Genetics , vol.12 , Issue.2 , pp. 191-194
    • Gowen, L.C.1    Johnson, B.L.2    Latour, A.M.3    Sulik, K.K.4    Koller, B.H.5
  • 23
    • 0025992469 scopus 로고
    • Promoter traps in embryonic stem cells: A genetic screen to identify and mutate developmental genes in mice
    • Friedrich G, Soriano P. 1991. Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev. 5:1513-23 (Pubitemid 21906058)
    • (1991) Genes and Development , vol.5 , Issue.9 , pp. 1513-1523
    • Friedrich, G.1    Soriano, P.2
  • 25
    • 0035953550 scopus 로고    scopus 로고
    • Somatic activation of the K-ras oncogene causes early onset lung cancer in mice
    • DOI 10.1038/35074129
    • Johnson L, Mercer K, Greenbaum D, Bronson RT, Crowley D, et al. 2001. Somatic activation of the K-ras oncogene causes early onset lung cancer in mice. Nature 410:1111-16 (Pubitemid 32391044)
    • (2001) Nature , vol.410 , Issue.6832 , pp. 1111-1116
    • Johnson, L.1    Mercer, K.2    Greenbaum, D.3    Bronson, R.T.4    Crowley, D.5    Tuveson, D.A.6    Jacks, T.7
  • 26
    • 0023046599 scopus 로고
    • The role of the loxP spacer region in P1 site-specific recombination
    • Hoess RH, Wierzbicki A, Abremski K. 1986. The role of the loxP spacer region in P1 site-specific recombination. Nucleic Acids Res. 14:2287-300
    • (1986) Nucleic Acids Res , vol.14 , pp. 2287-2300
    • Hoess, R.H.1    Wierzbicki, A.2    Abremski, K.3
  • 29
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain [1]
    • DOI 10.1038/5007
    • Soriano P. 1999. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 21:70-71 (Pubitemid 29036285)
    • (1999) Nature Genetics , vol.21 , Issue.1 , pp. 70-71
    • Soriano, P.1
  • 31
    • 0034794191 scopus 로고    scopus 로고
    • Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase
    • DOI 10.1038/nbt1001-929
    • Jo D, Nashabi A, Doxsee C, Lin Q, Unutmaz D, et al. 2001. Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase. Nat. Biotechnol. 19:929-33 (Pubitemid 32947570)
    • (2001) Nature Biotechnology , vol.19 , Issue.10 , pp. 929-933
    • Jo, D.1    Nashabi, A.2    Doxsee, C.3    Lin, Q.4    Unutmaz, D.5    Chen, J.6    Ruley, H.E.7
  • 33
    • 0033001621 scopus 로고    scopus 로고
    • Reversible activation of c-Myc in skin: Induction of a complex neoplastic phenotype by a single oncogenic lesion
    • DOI 10.1016/S1097-2765(00)80350-0
    • Pelengaris S, Littlewood T, Khan M, Elia G, Evan G. 1999. Reversible activation of c-myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion. Mol. Cell 3:565-77 (Pubitemid 29268440)
    • (1999) Molecular Cell , vol.3 , Issue.5 , pp. 565-577
    • Pelengaris, S.1    Littlewood, T.2    Khan, M.3    Elia, G.4    Evan, G.5
  • 34
    • 70149118758 scopus 로고    scopus 로고
    • The effects of tamoxifen and estradiol on myometrial differentiationand organization during early uterine development in the CD1mouse
    • MehassebMK, Bell SC, HabibaMA. 2009. The effects of tamoxifen and estradiol on myometrial differentiationand organization during early uterine development in the CD1mouse. Reproduction 138:341-50
    • (2009) Reproduction , vol.138 , pp. 341-350
    • Mehasseb, M.K.1    Bell, S.C.2    Habiba, M.A.3
  • 35
    • 66949153645 scopus 로고    scopus 로고
    • Direct hematological toxicity and illegitimate chromosomal recombination caused by the systemic activation of CreERT2
    • Higashi AY, IkawaT,Muramatsu M, Economides AN,Niwa A, et al. 2009. Direct hematological toxicity and illegitimate chromosomal recombination caused by the systemic activation of CreERT2. J. Immunol. 182:5633-40
    • (2009) J. Immunol. , vol.182 , pp. 5633-5640
    • Higashi, A.Y.1    Ikawa, T.2    Muramatsu, M.3    Economides, A.N.4    Niwa, A.5
  • 38
    • 0035490099 scopus 로고    scopus 로고
    • Engineering chromosomal rearrangements in mice
    • DOI 10.1038/35093564
    • Yu Y, Bradley A. 2001. Engineering chromosomal rearrangements in mice. Nat. Rev. Genet. 2:780-90 (Pubitemid 33685575)
    • (2001) Nature Reviews Genetics , vol.2 , Issue.10 , pp. 780-790
    • Yu, Y.1    Bradley, A.2
  • 39
    • 0034252564 scopus 로고    scopus 로고
    • Inducible chromosomal translocation of AML1 and ETO genes through Cre/loxP-mediated recombination in the mouse
    • Buchholz F, Refaeli Y, Trumpp A, Bishop JM. 2000. Inducible chromosomal translocation of AML1 and ETO genes through Cre/loxP-mediated recombination in the mouse. EMBO Rep. 1:133-39
    • (2000) EMBO Rep , vol.1 , pp. 133-139
    • Buchholz, F.1    Refaeli, Y.2    Trumpp, A.3    Bishop, J.M.4
  • 41
    • 26444461266 scopus 로고    scopus 로고
    • Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference
    • Coumoul X, Shukla V, Li C,Wang RH, Deng CX. 2005. Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference. Nucleic Acids Res. 33:e102
    • (2005) Nucleic Acids Res , vol.33
    • Coumoul, X.1    Shukla, V.2    Li, C.3    Wang, R.H.4    Deng, C.X.5
  • 43
    • 0038708339 scopus 로고    scopus 로고
    • Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype
    • DOI 10.1038/nbt813
    • Kunath T, Gish G, Lickert H, Jones N, Pawson T, et al. 2003. Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype. Nat. Biotechnol. 21:559-61 (Pubitemid 36532022)
    • (2003) Nature Biotechnology , vol.21 , Issue.5 , pp. 559-561
    • Kunath, T.1    Gish, G.2    Lickert, H.3    Jones, N.4    Pawson, T.5    Rossant, J.6
  • 46
    • 54049146099 scopus 로고    scopus 로고
    • Somatic cell gene transfer
    • ed. EC Holland, New York: Wiley
    • Uhrbom L, Holland EC. 2004. Somatic cell gene transfer. In Mouse Models of Human Cancer, ed. EC Holland, pp. 67-79. New York: Wiley
    • (2004) Mouse Models of Human Cancer , pp. 67-79
    • Uhrbom, L.1    Holland, E.C.2
  • 48
    • 13444269246 scopus 로고    scopus 로고
    • Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer
    • DOI 10.1038/nm1173
    • Dinulescu DM, Ince TA, Quade BJ, Shafer SA, Crowley D, et al. 2005. Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer. Nat. Med. 11:63-70 (Pubitemid 40215839)
    • (2005) Nature Medicine , vol.11 , Issue.1 , pp. 63-70
    • Dinulescu, D.M.1    Ince, T.A.2    Quade, B.J.3    Shafer, S.A.4    Crowley, D.5    Jacks, T.6
  • 50
    • 0036463949 scopus 로고    scopus 로고
    • Induction of ovarian cancer by defined multiple genetic changes in a mouse model system
    • DOI 10.1016/S1535-6108(01)00002-2
    • Orsulic S, Li Y, Soslow RA, Vitale-Cross LA, Gutkind JS, et al. 2002. Induction of ovarian cancer by defined multiple genetic changes in a mouse model system. Cancer Cell 1:53-62 (Pubitemid 41039176)
    • (2002) Cancer Cell , vol.1 , Issue.1 , pp. 53-62
    • Orsulic, S.1    Li, Y.2    Soslow, R.A.3    Vitale-Cross, L.A.4    Gutkind, J.S.5    Varmus, H.E.6
  • 51
    • 4444273153 scopus 로고    scopus 로고
    • Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice
    • DOI 10.1038/sj.onc.1207818
    • Rao G, Pedone CA, Del Valle L, Reiss K, Holland EC, et al. 2004. Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice. Oncogene 23:6156-62 (Pubitemid 39178868)
    • (2004) Oncogene , vol.23 , Issue.36 , pp. 6156-6162
    • Rao, G.1    Pedone, C.A.2    Valle, L.D.3    Reiss, K.4    Holland, E.C.5    Fults, D.W.6
  • 52
    • 74049163724 scopus 로고    scopus 로고
    • Chimeric mouse tumor models reveal differences in pathway activation between ERBB family- and KRAS-dependent lung adenocarcinomas
    • Zhou Y, Rideout WM 3rd, Zi T, Bressel A, Reddypalli S, et al. Chimeric mouse tumor models reveal differences in pathway activation between ERBB family- and KRAS-dependent lung adenocarcinomas. Nat. Biotechnol. 28:71-78
    • Nat. Biotechnol. , vol.28 , pp. 71-78
    • Zhou, Y.1    Rideout III, W.M.2    Zi, T.3    Bressel, A.4    Reddypalli, S.5
  • 54
    • 35148869096 scopus 로고    scopus 로고
    • Fly MARCM and mouse MADM: Genetic methods of labeling and manipulating single neurons
    • DOI 10.1016/j.brainresrev.2007.01.012, PII S0165017307000264
    • Luo L. 2007. Fly MARCM and mouse MADM: genetic methods of labeling and manipulating single neurons. Brain Res. Rev. 55:220-27 (Pubitemid 47538750)
    • (2007) Brain Research Reviews , vol.55 , Issue.2 SPEC. ISS. , pp. 220-227
    • Luo, L.1
  • 56
    • 65249130551 scopus 로고    scopus 로고
    • Uncoupling dendrite growth and patterning: Singlecell knockout analysis of NMDA receptor 2B
    • Espinosa JS,Wheeler DG, Tsien RW, Luo L. 2009. Uncoupling dendrite growth and patterning: singlecell knockout analysis of NMDA receptor 2B. Neuron 62:205-17
    • (2009) Neuron , vol.62 , pp. 205-217
    • Espinosa, J.S.1    Wheeler, D.G.2    Tsien, R.W.3    Luo, L.4
  • 60
    • 27944496521 scopus 로고    scopus 로고
    • Retroviral insertional mutagenesis: Past, present and future
    • DOI 10.1038/sj.onc.1209043, PII 1209043
    • Uren AG, Kool J, Berns A, van LohuizenM. 2005. Retroviral insertional mutagenesis: past, present and future. Oncogene 24:7656-72 (Pubitemid 41670669)
    • (2005) Oncogene , vol.24 , Issue.52 , pp. 7656-7672
    • Uren, A.G.1    Kool, J.2    Berns, A.3    Van Lohuizen, M.4
  • 61
    • 0021767931 scopus 로고
    • Involvement of c-myc in MuLV-induced T cell lymphomas in mice: Frequency and mechanisms of activation
    • Selten G, Cuypers HT, Zijlstra M, Melief C, Berns A. 1984. Involvement of c-myc in MuLV-induced T cell lymphomas in mice: frequency and mechanisms of activation. EMBO J. 3:3215-22
    • (1984) EMBO J , vol.3 , pp. 3215-3222
    • Selten, G.1    Cuypers, H.T.2    Zijlstra, M.3    Melief, C.4    Berns, A.5
  • 63
    • 0022100028 scopus 로고
    • Proviral activation of the putative oncogene Pim-1 in MuLV induced T-cell lymphomas
    • Selten G, Cuypers HT, Berns A. 1985. Proviral activation of the putative oncogene Pim-1 in MuLV induced T-cell lymphomas. EMBO J. 4:1793-98
    • (1985) EMBO J , vol.4 , pp. 1793-1798
    • Selten, G.1    Cuypers, H.T.2    Berns, A.3
  • 64
    • 33746569501 scopus 로고    scopus 로고
    • Tumor suppressor gene identification using retroviral insertional mutagenesis in Blm-deficient mice
    • DOI 10.1038/sj.emboj.7601215, PII 7601215
    • Suzuki T, Minehata K, AkagiK, Jenkins NA,CopelandNG. 2006. Tumor suppressor gene identification using retroviral insertional mutagenesis in Blm-deficient mice. EMBO J. 25:3422-31 (Pubitemid 44141798)
    • (2006) EMBO Journal , vol.25 , Issue.14 , pp. 3422-3431
    • Suzuki, T.1    Minehata, K.-I.2    Akagi, K.3    Jenkins, N.A.4    Copeland, N.G.5
  • 65
    • 0025863346 scopus 로고
    • Identification of cooperating oncogenes in Eμ-myc transgenic mice by provirus tagging
    • van Lohuizen M, Verbeek S, Scheijen B, Wientjens E, van der Gulden H, et al. 1991. Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging. Cell 65:737-52 (Pubitemid 121001306)
    • (1991) Cell , vol.65 , Issue.5 , pp. 737-752
    • Van Lohuizen, M.1    Verbeek, S.2    Scheijen, B.3    Wientjens, E.4    Van Der Gulden, H.5    Berns, A.6
  • 66
    • 3843115428 scopus 로고    scopus 로고
    • Identification of candidate cancercausing genes in mouse brain tumors by retroviral tagging
    • Johansson FK, Brodd J, EklofC, Ferletta M, Hesselager G, et al. 2004. Identification of candidate cancercausing genes in mouse brain tumors by retroviral tagging. Proc. Natl. Acad. Sci. USA 101:11334-37
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 11334-1137
    • Johansson, F.K.1    Brodd, J.2    Eklof, C.3    Ferletta, M.4    Hesselager, G.5
  • 68
    • 68349145078 scopus 로고    scopus 로고
    • Next-generation gene targeting in the mouse for functional genomics
    • Gondo Y, Fukumura R, Murata T, Makino S. 2009. Next-generation gene targeting in the mouse for functional genomics. BMB Rep. 42:315-23
    • (2009) BMB Rep , vol.42 , pp. 315-323
    • Gondo, Y.1    Fukumura, R.2    Murata, T.3    Makino, S.4
  • 69
    • 0025015168 scopus 로고
    • A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
    • Moser AR, Pitot HC, Dove WF. 1990. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 247:322-24
    • (1990) Science , vol.247 , pp. 322-324
    • Moser, A.R.1    Pitot, H.C.2    Dove, W.F.3
  • 70
    • 0026562404 scopus 로고
    • Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene
    • Su LK, Kinzler KW, Vogelstein B, Preisinger AC, Moser AR, et al. 1992. Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene. Science 256:668-70
    • (1992) Science , vol.256 , pp. 668-670
    • Su, L.K.1    Kinzler, K.W.2    Vogelstein, B.3    Preisinger, A.C.4    Moser, A.R.5
  • 71
    • 0026871980 scopus 로고
    • Genetic resolution of susceptibility to cancer-new perspectives
    • Demant P. 1992. Genetic resolution of susceptibility to cancer-new perspectives. Semin. Cancer Biol. 3:159-66
    • (1992) Semin. Cancer Biol. , vol.3 , pp. 159-166
    • Demant, P.1
  • 72
    • 0042881036 scopus 로고    scopus 로고
    • Cancer susceptibility in the mouse: Genetics, biology and implications for human cancer
    • DOI 10.1038/nrg1157
    • Demant P. 2003. Cancer susceptibility in the mouse: genetics, biology and implications for human cancer. Nat. Rev. Genet. 4:721-34 (Pubitemid 37046139)
    • (2003) Nature Reviews Genetics , vol.4 , Issue.9 , pp. 721-734
    • Demant, P.1
  • 73
    • 0036649023 scopus 로고    scopus 로고
    • Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers
    • Ruivenkamp CA, van Wezel T, Zanon C, Stassen AP, Vlcek C, et al. 2002. Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers. Nat. Genet. 31:295-300
    • (2002) Nat. Genet. , vol.31 , pp. 295-300
    • Ruivenkamp, C.A.1    Van Wezel, T.2    Zanon, C.3    Stassen, A.P.4    Vlcek, C.5
  • 76
    • 22444444402 scopus 로고    scopus 로고
    • Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse
    • DOI 10.1038/nature03681
    • Collier LS, Carlson CM, Ravimohan S, Dupuy AJ, Largaespada DA. 2005. Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse. Nature 436:272-76 (Pubitemid 41021279)
    • (2005) Nature , vol.436 , Issue.7048 , pp. 272-276
    • Collier, L.S.1    Carlson, C.M.2    Ravimohan, S.3    Dupuy, A.J.4    Largaespada, D.A.5
  • 77
    • 22444431606 scopus 로고    scopus 로고
    • Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system
    • DOI 10.1038/nature03691
    • Dupuy AJ, Akagi K, Largaespada DA, Copeland NG, Jenkins NA. 2005. Mammalian mutagenesis using a highly mobile somatic sleeping beauty transposon system. Nature 436:221-26 (Pubitemid 41021267)
    • (2005) Nature , vol.436 , Issue.7048 , pp. 221-226
    • Dupuy, A.J.1    Akagi, K.2    Largaespada, D.A.3    Copeland, N.G.4    Jenkins, N.A.5
  • 78
    • 62149116794 scopus 로고    scopus 로고
    • A conditional transposonbased insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma
    • Keng VW, Villanueva A, Chiang DY, Dupuy AJ, Ryan BJ, et al. 2009. A conditional transposonbased insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma. Nat. Biotechnol. 27:264-74
    • (2009) Nat. Biotechnol. , vol.27 , pp. 264-274
    • Keng, V.W.1    Villanueva, A.2    Chiang, D.Y.3    Dupuy, A.J.4    Ryan, B.J.5
  • 79
    • 63049105067 scopus 로고    scopus 로고
    • A transposon-based genetic screen in mice identifies genes altered in colorectal cancer
    • Starr TK, Allaei R, Silverstein KA, Staggs RA, Sarver AL, et al. 2009. A transposon-based genetic screen in mice identifies genes altered in colorectal cancer. Science 323:1747-50
    • (2009) Science , vol.323 , pp. 1747-1750
    • Starr, T.K.1    Allaei, R.2    Silverstein, K.A.3    Staggs, R.A.4    Sarver, A.L.5
  • 80
    • 70350227239 scopus 로고    scopus 로고
    • A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in mice
    • Dupuy AJ, Rogers LM, Kim J, Nannapaneni K, Starr TK, et al. 2009. A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in mice. Cancer Res. 69:8150-56
    • (2009) Cancer Res , vol.69 , pp. 8150-8156
    • Dupuy, A.J.1    Rogers, L.M.2    Kim, J.3    Nannapaneni, K.4    Starr, T.K.5
  • 81
    • 27544512127 scopus 로고    scopus 로고
    • Hopping around the tumor genome: Transposons for cancer gene discovery
    • DOI 10.1158/0008-5472.CAN-05-3085
    • Collier LS, Largaespada DA. 2005. Hopping around the tumor genome: transposons for cancer gene discovery. Cancer Res. 65:9607-10 (Pubitemid 41541432)
    • (2005) Cancer Research , vol.65 , Issue.21 , pp. 9607-9610
    • Collier, L.S.1    Largaespada, D.A.2
  • 82
    • 0034623009 scopus 로고    scopus 로고
    • Sleeping beauty, a wide host-range transposon vector for genetic transformation in vertebrates
    • Izsvak Z, Ivics Z, Plasterk RH. 2000. Sleeping beauty, a wide host-range transposon vector for genetic transformation in vertebrates. J. Mol. Biol. 302:93-102
    • (2000) J. Mol. Biol. , vol.302 , pp. 93-102
    • Izsvak, Z.1    Ivics, Z.2    Plasterk, R.H.3
  • 84
    • 34547638572 scopus 로고    scopus 로고
    • Generation of an inducible and optimized piggyBac transposon system
    • Cadinanos J, Bradley A. 2007. Generation of an inducible and optimized piggyBac transposon system. Nucleic Acids Res. 35:e87
    • (2007) Nucleic Acids Res , vol.35
    • Cadinanos, J.1    Bradley, A.2
  • 85
    • 23744479962 scopus 로고    scopus 로고
    • Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice
    • DOI 10.1016/j.cell.2005.07.013, PII S0092867405007075
    • Ding S,WuX, Li G, HanM,ZhuangY, et al. 2005. Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice. Cell 122:473-83 (Pubitemid 41127147)
    • (2005) Cell , vol.122 , Issue.3 , pp. 473-483
    • Ding, S.1    Wu, X.2    Li, G.3    Han, M.4    Zhuang, Y.5    Xu, T.6
  • 86
    • 34347337601 scopus 로고    scopus 로고
    • Toward simpler and faster genome-wide mutagenesis in mice
    • DOI 10.1038/ng2060, PII NG2060
    • Wu S, Ying G, Wu Q, Capecchi MR. 2007. Toward simpler and faster genome-wide mutagenesis in mice. Nat. Genet. 39:922-30 (Pubitemid 47014495)
    • (2007) Nature Genetics , vol.39 , Issue.7 , pp. 922-930
    • Wu, S.1    Ying, G.2    Wu, Q.3    Capecchi, M.R.4
  • 87
    • 37049202712 scopus 로고
    • A note on ovarian secretion and cancer
    • MurrayWS. 1928. A note on ovarian secretion and cancer. Science 67:396-97
    • (1928) Science , vol.67 , pp. 396-397
    • Murray, W.S.1
  • 88
    • 0017372823 scopus 로고
    • Effects of tamoxifen in relation to breast cancer
    • Jordan VC. 1977. Effects of tamoxifen in relation to breast cancer. Br. Med. J. 1:1534-35 (Pubitemid 8115362)
    • (1977) British Medical Journal , vol.1 , Issue.6075 , pp. 1534-1535
    • Jordan, V.C.1
  • 89
    • 0344641797 scopus 로고
    • The influence of the degree of caloric restriction on the formation of skin tumors and hepatomas in mice
    • Tannenbaum A, SilverstoneH. 1949. The influence of the degree of caloric restriction on the formation of skin tumors and hepatomas in mice. Cancer Res. 9:724-27
    • (1949) Cancer Res , vol.9 , pp. 724-727
    • Tannenbaum, A.1    Silverstone, H.2
  • 91
    • 0034660887 scopus 로고    scopus 로고
    • Accelerated ultraviolet radiation-induced carcinogenesis in hepatocyte growth factor/scatter factor transgenic mice
    • Noonan FP, Otsuka T, Bang S, Anver MR, Merlino G. 2000. Accelerated UV radiation-induced carcinogenesis in hepatocyte growth factor/scatter factor transgenic mice. Cancer Res. 60:3738-43 (Pubitemid 32204561)
    • (2000) Cancer Research , vol.60 , Issue.14 , pp. 3738-3743
    • Noonan, F.P.1    Otsuka, T.2    Bang, S.3    Anver, M.R.4    Merlino, G.5
  • 93
    • 0032694528 scopus 로고    scopus 로고
    • Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice
    • DOI 10.1038/15242
    • Aszterbaum M, Epstein J, Oro A, Douglas V, LeBoit PE, et al. 1999. Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice. Nat. Med. 5:1285-91 (Pubitemid 29535606)
    • (1999) Nature Medicine , vol.5 , Issue.11 , pp. 1285-1291
    • Aszterbaum, M.1    Epstein, J.2    Anthony, O.3    Douglas, V.4    Leboit, P.E.5    Scott, M.P.6    Epstein Jr., E.H.7
  • 94
    • 0035936026 scopus 로고    scopus 로고
    • Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of β-catenin-mutated mouse liver tumors
    • DOI 10.1038/sj/onc/1204982
    • Aydinlik H, Nguyen TD, Moennikes O, Buchmann A, Schwarz M. 2001. Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of â-catenin-mutated mouse liver tumors. Oncogene 20:7812-16 (Pubitemid 33121956)
    • (2001) Oncogene , vol.20 , Issue.53 , pp. 7812-7816
    • Aydinlik, H.1    Nguyen, T.D.2    Moennikes, O.3    Buchmann, A.4    Schwarz, M.5
  • 95
    • 13644251904 scopus 로고    scopus 로고
    • Advances in imaging mouse tumour models in vivo
    • DOI 10.1002/path.1697
    • Lyons SK. 2005. Advances in imaging mouse tumor models in vivo. J. Pathol. 205:194-205 (Pubitemid 40227991)
    • (2005) Journal of Pathology , vol.205 , Issue.2 , pp. 194-205
    • Lyons, S.K.1
  • 97
    • 62449135386 scopus 로고    scopus 로고
    • Imaging cancer dynamics in vivo at the tumor and cellular level with fluorescent proteins
    • Hoffman RM. 2009. Imaging cancer dynamics in vivo at the tumor and cellular level with fluorescent proteins. Clin. Exp. Metastasis 26:345-55
    • (2009) Clin. Exp. Metastasis , vol.26 , pp. 345-355
    • Hoffman, R.M.1
  • 100
    • 0037086089 scopus 로고    scopus 로고
    • Noninvasive imaging of spontaneous retinoblastoma pathway-dependent tumors in mice
    • Vooijs M, Jonkers J, Lyons S, Berns A. 2002. Noninvasive imaging of spontaneous retinoblastoma pathway-dependent tumors in mice. Cancer Res. 62:1862-67 (Pubitemid 34408514)
    • (2002) Cancer Research , vol.62 , Issue.6 , pp. 1862-1867
    • Vooijs, M.1    Jonkers, J.2    Lyons, S.3    Berns, A.4
  • 103
    • 56349121125 scopus 로고    scopus 로고
    • An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer
    • Zender L, Xue W, Zuber J, Semighini CP, Krasnitz A, et al. 2008. An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer. Cell 135:852-64
    • (2008) Cell , vol.135 , pp. 852-864
    • Zender, L.1    Xue, W.2    Zuber, J.3    Semighini, C.P.4    Krasnitz, A.5
  • 105
    • 70349454058 scopus 로고    scopus 로고
    • Functional identification of tumorsuppressor genes through an in vivo RNA interference screen in a mouse lymphoma model
    • Bric A, Miething C, Bialucha CU, Scuoppo C, Zender L, et al. 2009. Functional identification of tumorsuppressor genes through an in vivo RNA interference screen in a mouse lymphoma model. Cancer Cell 16:324-35
    • (2009) Cancer Cell , vol.16 , pp. 324-335
    • Bric, A.1    Miething, C.2    Bialucha, C.U.3    Scuoppo, C.4    Zender, L.5
  • 106
    • 0033617532 scopus 로고    scopus 로고
    • Effects of angiogenesis inhibitors on multistage carcinogenesis in mice
    • DOI 10.1126/science.284.5415.808
    • Bergers G, Javaherian K, Lo KM, Folkman J, Hanahan D. 1999. Effects of angiogenesis inhibitors on multistage carcinogenesis in mice. Science 284:808-12 (Pubitemid 29291347)
    • (1999) Science , vol.284 , Issue.5415 , pp. 808-812
    • Bergers, G.1    Javaherian, K.2    Lo, K.-M.3    Folkman, J.4    Hanahan, D.5
  • 107
    • 1942503022 scopus 로고    scopus 로고
    • SU5416 selectively impairs angiogenesis to induce prostate cancer-specific apoptosis
    • Huss WJ, Barrios RJ, Greenberg NM. 2003. SU5416 selectively impairs angiogenesis to induce prostate cancer-specific apoptosis. Mol. Cancer Ther. 2:611-16
    • (2003) Mol. Cancer Ther. , vol.2 , pp. 611-616
    • Huss, W.J.1    Barrios, R.J.2    Greenberg, N.M.3
  • 108
    • 64349109459 scopus 로고    scopus 로고
    • Mouse models of human AML accurately predict chemotherapy response
    • Zuber J, Radtke I, Pardee TS, Zhao Z, Rappaport AR, et al. 2009. Mouse models of human AML accurately predict chemotherapy response. Genes Dev. 23:877-89
    • (2009) Genes Dev , vol.23 , pp. 877-889
    • Zuber, J.1    Radtke, I.2    Pardee, T.S.3    Zhao, Z.4    Rappaport, A.R.5
  • 109
    • 33748331308 scopus 로고    scopus 로고
    • The mighty mouse: Genetically engineered mouse models in cancer drug development
    • DOI 10.1038/nrd2110, PII NRD2110
    • Sharpless NE, Depinho RA. 2006. The mighty mouse: genetically engineered mouse models in cancer drug development. Nat. Rev. Drug Discov. 5:741-54 (Pubitemid 44323701)
    • (2006) Nature Reviews Drug Discovery , vol.5 , Issue.9 , pp. 741-754
    • Sharpless, N.E.1    DePinho, R.A.2
  • 111
    • 26644471951 scopus 로고    scopus 로고
    • Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
    • DOI 10.1016/j.ccr.2005.09.005, PII S1535610805002989
    • Casanovas O, Hicklin DJ, Bergers G, Hanahan D. 2005. Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors. Cancer Cell 8:299-309 (Pubitemid 41443415)
    • (2005) Cancer Cell , vol.8 , Issue.4 , pp. 299-309
    • Casanovas, O.1    Hicklin, D.J.2    Bergers, G.3    Hanahan, D.4
  • 113
    • 0034730198 scopus 로고    scopus 로고
    • Retinoic acid (RA) and As2O3 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RARáand PLZF-RARáoncoproteins
    • Rego EM, He LZ, Warrell RP Jr, Wang ZG, Pandolfi PP. 2000. Retinoic acid (RA) and As2O3 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RARáand PLZF-RARáoncoproteins. Proc. Natl. Acad. Sci. USA 97:10173-78
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 10173-10178
    • Rego, E.M.1    He, L.Z.2    Warrell Jr., R.P.3    Wang, Z.G.4    Pandolfi, P.P.5
  • 115
    • 41649100689 scopus 로고    scopus 로고
    • Mining the plasma proteome for cancer biomarkers
    • DOI 10.1038/nature06916, PII NATURE06916
    • Hanash SM, Pitteri SJ, Faca VM. 2008. Mining the plasma proteome for cancer biomarkers. Nature 452:571-79 (Pubitemid 351483371)
    • (2008) Nature , vol.452 , Issue.7187 , pp. 571-579
    • Hanash, S.M.1    Pitteri, S.J.2    Faca, V.M.3
  • 117
    • 46349104324 scopus 로고    scopus 로고
    • A mouse to human search for plasma proteome changes associated with pancreatic tumor development
    • Faca VM, Song KS, Wang H, Zhang Q, Krasnoselsky AL, et al. 2008. A mouse to human search for plasma proteome changes associated with pancreatic tumor development. PLoS Med. 5:e123
    • (2008) PLoS Med , vol.5
    • Faca, V.M.1    Song, K.S.2    Wang, H.3    Zhang, Q.4    Krasnoselsky, A.L.5
  • 118
    • 68349105689 scopus 로고    scopus 로고
    • Comprehensive proteome analysis of an Apc mouse model uncovers proteins associated with intestinal tumorigenesis
    • Hung KE, Faca V, Song K, Sarracino DA, Richard LG, et al. 2009. Comprehensive proteome analysis of an Apc mouse model uncovers proteins associated with intestinal tumorigenesis. Cancer Prev. Res. 2:224-33
    • (2009) Cancer Prev. Res. , vol.2 , pp. 224-233
    • Hung, K.E.1    Faca, V.2    Song, K.3    Sarracino, D.A.4    Richard, L.G.5
  • 120
    • 71049162589 scopus 로고    scopus 로고
    • Integrated proteomic analysis of human cancer cells and plasma from tumor bearing mice for ovarian cancer biomarker discovery
    • Pitteri SJ, JeBailey L, Faca VM, Thorpe JD, Silva MA, et al. 2009. Integrated proteomic analysis of human cancer cells and plasma from tumor bearing mice for ovarian cancer biomarker discovery. PLoS One 4:e7916
    • (2009) PLoS One , vol.4
    • Pitteri, S.J.1    Jebailey, L.2    Faca, V.M.3    Thorpe, J.D.4    Silva, M.A.5
  • 121
    • 70350534843 scopus 로고    scopus 로고
    • Hedgehog target genes: Mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation
    • Katoh Y, Katoh M. 2009. Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation. Curr. Mol. Med. 9:873-86
    • (2009) Curr. Mol. Med. , vol.9 , pp. 873-886
    • Katoh, Y.1    Katoh, M.2
  • 122
    • 33846193290 scopus 로고    scopus 로고
    • The many ways ofWnt in cancer
    • Polakis P. 2007. The many ways ofWnt in cancer. Curr. Opin. Genet. Dev. 17:45-51
    • (2007) Curr. Opin. Genet. Dev. , vol.17 , pp. 45-51
    • Polakis, P.1
  • 123
    • 0034946638 scopus 로고    scopus 로고
    • Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis
    • DOI 10.1038/90108
    • Xu X, Qiao W, Linke SP, Cao L, LiWM, et al. 2001. Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis. Nat. Genet. 28:266-71 (Pubitemid 32626030)
    • (2001) Nature Genetics , vol.28 , Issue.3 , pp. 266-271
    • Xu, X.1    Qiao, W.2    Linke, S.P.3    Cao, L.4    Li, W.-M.5    Furth, P.A.6    Harris, C.C.7    Deng, C.-X.8
  • 125
  • 126
    • 0032511848 scopus 로고    scopus 로고
    • The murine gene p27(Kip 1) is haplo-insufficient for tumour suppression
    • DOI 10.1038/24179
    • Fero ML, Randel E, Gurley KE, Roberts JM, Kemp CJ. 1998. The murine gene p27Kip1 is haploinsufficient for tumor suppression. Nature 396:177-80 (Pubitemid 28523620)
    • (1998) Nature , vol.396 , Issue.6707 , pp. 177-180
    • Fero, M.L.1    Randel, E.2    Gurley, K.E.3    Roberts, J.M.4    Kemp, C.J.5
  • 127
    • 33749482498 scopus 로고    scopus 로고
    • A mouse model for the molecular characterization of Brca1-associated ovarian carcinoma
    • DOI 10.1158/0008-5472.CAN-06-1495
    • Xing D, Orsulic S. 2006. A mouse model for the molecular characterization of Brca1-associated ovarian carcinoma. Cancer Res. 66:8949-53 (Pubitemid 44521109)
    • (2006) Cancer Research , vol.66 , Issue.18 , pp. 8949-8953
    • Xing, D.1    Orsulic, S.2
  • 132
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia - A key regulatory factor in tumour growth
    • Harris AL. 2002. Hypoxia-a key regulatory factor in tumor growth. Nat. Rev. Cancer 2:38-47 (Pubitemid 37328806)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.1 , pp. 38-47
    • Harris, A.L.1
  • 133
    • 34547630698 scopus 로고    scopus 로고
    • Tumor angiogenesis: Cause or consequence of cancer?
    • DOI 10.1158/0008-5472.CAN-07-2053
    • Shchors K, Evan G. 2007. Tumor angiogenesis: cause or consequence of cancer? Cancer Res. 67:7059-61 (Pubitemid 47206529)
    • (2007) Cancer Research , vol.67 , Issue.15 , pp. 7059-7061
    • Shchors, K.1    Evan, G.2
  • 135
    • 28944432805 scopus 로고    scopus 로고
    • Selective evolution of stromal mesenchyme with p53 loss in response to epithelial tumorigenesis
    • DOI 10.1016/j.cell.2005.09.030, PII S0092867405010366
    • Hill R, Song Y, Cardiff RD, Van Dyke T. 2005. Selective evolution of stromal mesenchyme with p53 loss in response to epithelial tumorigenesis. Cell 123:1001-11 (Pubitemid 41785416)
    • (2005) Cell , vol.123 , Issue.6 , pp. 1001-1011
    • Hill, R.1    Song, Y.2    Cardiff, R.D.3    Van Dyke, T.4
  • 136
    • 58149215849 scopus 로고    scopus 로고
    • Prostate tumor progression is mediated by a paracrine TGF-â/Wnt3a signaling axis
    • Li X, Placencio V, Iturregui JM,Uwamariya C, Sharif-Afshar AR, et al. 2008. Prostate tumor progression is mediated by a paracrine TGF-â/Wnt3a signaling axis. Oncogene 27:7118-30
    • (2008) Oncogene , vol.27 , pp. 7118-7130
    • Li, X.1    Placencio, V.2    Iturregui, J.M.3    Uwamariya, C.4    Sharif-Afshar, A.R.5
  • 137
    • 48749118242 scopus 로고    scopus 로고
    • Combinatorial patterns of somatic gene mutations in cancer
    • Yeang CH, McCormick F, Levine A. 2008. Combinatorial patterns of somatic gene mutations in cancer. FASEB J. 22:2605-22
    • (2008) FASEB J , vol.22 , pp. 2605-2622
    • Yeang, C.H.1    McCormick, F.2    Levine, A.3
  • 138
    • 33745240353 scopus 로고    scopus 로고
    • Cross-species oncogenomics in cancer gene identification
    • DOI 10.1016/j.cell.2006.06.018, PII S0092867406007768
    • Peeper D, Berns A. 2006. Cross-species oncogenomics in cancer gene identification. Cell 125:1230-33 (Pubitemid 43929103)
    • (2006) Cell , vol.125 , Issue.7 , pp. 1230-1233
    • Peeper, D.1    Berns, A.2
  • 139
    • 0035545961 scopus 로고    scopus 로고
    • Building 'validated' mouse models of human cancer
    • DOI 10.1016/S0955-0674(00)00283-0
    • Hann B, Balmain A. 2001. Building "validated" mouse models of human cancer. Curr. Opin. Cell Biol. 13:778-84 (Pubitemid 33042740)
    • (2001) Current Opinion in Cell Biology , vol.13 , Issue.6 , pp. 778-784
    • Hann, B.1    Balmain, A.2
  • 140
    • 1342288971 scopus 로고    scopus 로고
    • Comparative biology of mouse versus human cells: Modelling human cancer in mice
    • Rangarajan A, Weinberg RA. 2003. Opinion. Comparative biology of mouse versus human cells: modelling human cancer in mice. Nat. Rev. Cancer 3:952-59 (Pubitemid 37500180)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.12 , pp. 952-959
    • Rangarajan, A.1    Weinberg, R.A.2
  • 143
    • 1842481560 scopus 로고    scopus 로고
    • Advances in molecular carcinogenesis: current and future use of mousemodels to screen and validatemolecularly targeted anticancer drugs
    • DOI 10.1002/mc.20013
    • Frijhoff AF, Conti CJ, Senderowicz AM. 2004. Advances in molecular carcinogenesis: current and future use ofmousemodels to screen and validatemolecularly targeted anticancer drugs. Mol. Carcinog. 39:183-94 (Pubitemid 38452238)
    • (2004) Molecular Carcinogenesis , vol.39 , Issue.4 , pp. 183-194
    • Frijhoff, A.F.W.1    Conti, C.J.2    Senderowicz, A.M.3


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