Manipulating the Mouse Genome to Engineer Precise Functional Syntenic Replacements with Human Sequence

Cell

Volumn 128, Issue 1, 2007, Pages 197-209

  Wallace, Helen A C ^a   Marques Kranc, Fatima ^b   Richardson, Melville ^a   Luna Crespo, Francisco ^a   Sharpe, Jackie A ^b   Hughes, Jim ^b   Wood, William G ^b   Higgs, Douglas R ^b   Smith, Andrew J H ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GLOBIN; CRE RECOMBINASE; RECOMBINASE;

ALPHA THALASSEMIA; ANIMAL CELL; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CONTROLLED STUDY; DISEASE MODEL; EMBRYO CELL; FEASIBILITY STUDY; GENE EXPRESSION; GENETIC DISORDER; GENETIC ENGINEERING; GENETIC MODEL; GENETIC PROCEDURES; GENETIC RECOMBINATION; GENOME ANALYSIS; GENOMIC FRAGMENT; HOMOZYGOTE; HUMAN; HUMAN CELL; LOXP SITE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RECOMBINASE MEDIATED GENOMIC REPLACEMENT; SEQUENCE ANALYSIS; SYNTENY; TRANSGENICS;

MUS;

EID: 33846011896     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2006.11.044     Document Type: Article

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