메뉴 건너뛰기




Volumn 436, Issue 7048, 2005, Pages 272-276

Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse

Author keywords

[No Author keywords available]

Indexed keywords

GENES; GENETIC ENGINEERING; MUTAGENS; TISSUE;

EID: 22444444402     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature03681     Document Type: Article
Times cited : (357)

References (27)
  • 1
    • 0036780602 scopus 로고    scopus 로고
    • Retroviral insertion sites and cancer: Fountain of all knowledge?
    • Neil, J. C. & Cameron, E. R. Retroviral insertion sites and cancer: fountain of all knowledge? Cancer Cell 2, 253-255 (2002).
    • (2002) Cancer Cell , vol.2 , pp. 253-255
    • Neil, J.C.1    Cameron, E.R.2
  • 2
    • 0029892554 scopus 로고    scopus 로고
    • Retroviral insertional mutagenesis as a strategy to identify cancer genes
    • Jonkers, J. & Berns, A. Retroviral insertional mutagenesis as a strategy to identify cancer genes. Biochim. Biophys. Acta 1287, 29-57 (1996).
    • (1996) Biochim. Biophys. Acta , vol.1287 , pp. 29-57
    • Jonkers, J.1    Berns, A.2
  • 3
    • 0030662074 scopus 로고    scopus 로고
    • Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells
    • Ivics, Z., Hackett, P. B., Plasterk, R. H. & Izsvak, Z. Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells. Cell 91, 501-510 (1997).
    • (1997) Cell , vol.91 , pp. 501-510
    • Ivics, Z.1    Hackett, P.B.2    Plasterk, R.H.3    Izsvak, Z.4
  • 4
    • 0034964286 scopus 로고    scopus 로고
    • Transposition and gene disruption in the male germline of the mouse
    • Dupuy, A. J., Fritz, S. & Largaespada, D. A. Transposition and gene disruption in the male germline of the mouse. Genesis 30, 82-88 (2001).
    • (2001) Genesis , vol.30 , pp. 82-88
    • Dupuy, A.J.1    Fritz, S.2    Largaespada, D.A.3
  • 5
    • 0035979255 scopus 로고    scopus 로고
    • Efficient chromosomal transposition of a Tc1/mariner-like transposon Sleeping Beauty in mice
    • Horie, K. et al. Efficient chromosomal transposition of a Tc1/mariner-like transposon Sleeping Beauty in mice. Proc. Natl Acad. Sci. USA 98, 9191-9196 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 9191-9196
    • Horie, K.1
  • 6
    • 0035810931 scopus 로고    scopus 로고
    • Regulated transposition of a fish transposon in the mouse germ line
    • Fischer, S. E., Wienholds, E. & Plasterk, R. H. Regulated transposition of a fish transposon in the mouse germ line. Proc. Natl Acad. Sci. USA 98, 6759-6764 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 6759-6764
    • Fischer, S.E.1    Wienholds, E.2    Plasterk, R.H.3
  • 7
    • 0034103009 scopus 로고    scopus 로고
    • Somatic integration and long-term transgene expression in normal and haemophilia mice using a DNA transposon system
    • Yant, S. R. et al. Somatic integration and long-term transgene expression in normal and haemophilia mice using a DNA transposon system. Nature Genet. 25, 35-41 (2000).
    • (2000) Nature Genet. , vol.25 , pp. 35-41
    • Yant, S.R.1
  • 8
    • 0036932834 scopus 로고    scopus 로고
    • In vivo correction of murine tyrosinemia type I by DNA-mediated transposition
    • Montini, E. et al. In vivo correction of murine tyrosinemia type I by DNA-mediated transposition. Mol. Ther. 6, 759-769 (2002).
    • (2002) Mol. Ther. , vol.6 , pp. 759-769
    • Montini, E.1
  • 9
    • 0029799791 scopus 로고    scopus 로고
    • A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: Polyethylenimine
    • Abdallah, B. et al. A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: polyethylenimine. Hum. Gene Ther. 7, 1947-1954 (1996).
    • (1996) Hum. Gene Ther. , vol.7 , pp. 1947-1954
    • Abdallah, B.1
  • 10
    • 0028385758 scopus 로고
    • Versatile retroviral vectors for potential use in gene therapy
    • Hawley, R. G., Lieu, F. H., Fong, A. Z. & Hawley, T. S. Versatile retroviral vectors for potential use in gene therapy. Gene Ther. 1, 136-138 (1994).
    • (1994) Gene Ther. , vol.1 , pp. 136-138
    • Hawley, R.G.1    Lieu, F.H.2    Fong, A.Z.3    Hawley, T.S.4
  • 13
    • 0030728468 scopus 로고    scopus 로고
    • Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
    • Kamijo, T. et al. Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF. Cell 91, 649-659 (1997).
    • (1997) Cell , vol.91 , pp. 649-659
    • Kamijo, T.1
  • 15
    • 0037841763 scopus 로고    scopus 로고
    • Transcription start regions in the human genome are favored targets for MLV integration
    • Wu, X., Li, Y., Crise, B. & Burgess, S. M. Transcription start regions in the human genome are favored targets for MLV integration. Science 300, 1749-1751 (2003).
    • (2003) Science , vol.300 , pp. 1749-1751
    • Wu, X.1    Li, Y.2    Crise, B.3    Burgess, S.M.4
  • 16
    • 0036404918 scopus 로고    scopus 로고
    • Common physical properties of DNA affecting target site selection of sleeping beauty and other Tc1/mariner transposable elements
    • Vigdal, T. J., Kaufman, C. D., Izsvak, Z., Voytas, D. F. & Ivics, Z. Common physical properties of DNA affecting target site selection of sleeping beauty and other Tc1/mariner transposable elements. J. Mol. Biol. 323, 441-452 (2002).
    • (2002) J. Mol. Biol. , vol.323 , pp. 441-452
    • Vigdal, T.J.1    Kaufman, C.D.2    Izsvak, Z.3    Voytas, D.F.4    Ivics, Z.5
  • 17
    • 0141566659 scopus 로고    scopus 로고
    • Transposon mutagenesis of the mouse germline
    • Carlson, C. M. et al. Transposon mutagenesis of the mouse germline. Genetics 165, 243-256 (2003).
    • (2003) Genetics , vol.165 , pp. 243-256
    • Carlson, C.M.1
  • 18
    • 10744231615 scopus 로고    scopus 로고
    • Characterization of Sleeping Beauty transposition and its application to genetic screening in mice
    • Horie, K. et al. Characterization of Sleeping Beauty transposition and its application to genetic screening in mice. Mol. Cell. Biol. 23, 9189-9207 (2003).
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 9189-9207
    • Horie, K.1
  • 19
    • 0036729878 scopus 로고    scopus 로고
    • High-throughput retroviral tagging to identify components of specific signalling pathways in cancer
    • Mikkers, H. et al. High-throughput retroviral tagging to identify components of specific signalling pathways in cancer. Nature Genet. 32, 153-159 (2002).
    • (2002) Nature Genet. , vol.32 , pp. 153-159
    • Mikkers, H.1
  • 20
    • 3843115428 scopus 로고    scopus 로고
    • Identification of candidate cancer-causing genes in mouse brain tumors by retroviral tagging
    • Johansson, F. K. et al. Identification of candidate cancer-causing genes in mouse brain tumors by retroviral tagging. Proc. Natl Acad. Sci. USA 101, 11334-11337 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 11334-11337
    • Johansson, F.K.1
  • 21
    • 22444431606 scopus 로고    scopus 로고
    • Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system
    • doi:10.1038/nature03691 (this issue)
    • Dupuy, A. J., Akagi, K., Largaespada, D. A., Copeland, N. G. & Jenkins, N. A. Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system. Nature doi:10.1038/nature03691 (this issue).
    • Nature
    • Dupuy, A.J.1    Akagi, K.2    Largaespada, D.A.3    Copeland, N.G.4    Jenkins, N.A.5
  • 23
    • 0036725322 scopus 로고    scopus 로고
    • Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice
    • Lund, A. H. et al. Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice. Nature Genet. 32, 160-165 (2002).
    • (2002) Nature Genet. , vol.32 , pp. 160-165
    • Lund, A.H.1
  • 24
    • 18444374405 scopus 로고    scopus 로고
    • Mutations of the BRAF gene in human cancer
    • Davies, H. et al. Mutations of the BRAF gene in human cancer. Nature 417, 949-954 (2002).
    • (2002) Nature , vol.417 , pp. 949-954
    • Davies, H.1
  • 25
    • 14044279223 scopus 로고    scopus 로고
    • Alterations of cancer-related genes in soft tissue sarcomas: Hypermethylation of RASSF1A is frequently detected in leiomyosarcoma and associated with poor prognosis in sarcoma
    • Seidel, C. et al. Alterations of cancer-related genes in soft tissue sarcomas: hypermethylation of RASSF1A is frequently detected in leiomyosarcoma and associated with poor prognosis in sarcoma. Int. J. Cancer 114, 442-447 (2005).
    • (2005) Int. J. Cancer , vol.114 , pp. 442-447
    • Seidel, C.1
  • 26
    • 0025277489 scopus 로고
    • Mutational activation of c-raf-1 and definition of the minimal transforming sequence
    • Heidecker, G. et al. Mutational activation of c-raf-1 and definition of the minimal transforming sequence. Mol. Cell. Biol. 10, 2503-2512 (1990).
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 2503-2512
    • Heidecker, G.1
  • 27
    • 0042700227 scopus 로고    scopus 로고
    • Gene transfer into genomes of human cells by the Sleeping Beauty transposon system
    • Geurts, A. M. et al. Gene transfer into genomes of human cells by the Sleeping Beauty transposon system. Mol. Ther. 8, 108-117 (2003).
    • (2003) Mol. Ther. , vol.8 , pp. 108-117
    • Geurts, A.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.