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Volumn 11, Issue 9, 2010, Pages 1059-1073

Small players with big roles: MicroRNAs as targets to inhibit breast cancer progression

Author keywords

Breast cancer; miRNA; Novel therapeutics; Stem cells

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; MICRORNA; MICRORNA 107; MICRORNA 10A; MICRORNA 10B; MICRORNA 125A; MICRORNA 125B; MICRORNA 126; MICRORNA 130A; MICRORNA 143; MICRORNA 145; MICRORNA 146A; MICRORNA 146B; MICRORNA 15; MICRORNA 150; MICRORNA 154; MICRORNA 16; MICRORNA 17 5P; MICRORNA 21; MICRORNA 22; MICRORNA 26A; MICRORNA 26B; MICRORNA 29B; MICRORNA 30A 5P; MICRORNA 30B; MICRORNA 30C; MICRORNA 30D; MICRORNA 31; MICRORNA 9; PROTEIN P53; UNCLASSIFIED DRUG;

EID: 78651338744     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/138945010792006762     Document Type: Article
Times cited : (33)

References (173)
  • 1
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281.
    • (2004) Cell , vol.116 , pp. 281
    • Bartel, D.P.1
  • 2
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge CB Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005; 120(1): 15-20.
    • (2005) Cell , vol.120 , Issue.1 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 3
    • 33344477448 scopus 로고    scopus 로고
    • Genomics of microRNA
    • Kim VN Nam JW. Genomics of microRNA. Trends Genet 2006; 22(3): 165-73.
    • (2006) Trends Genet , vol.22 , Issue.3 , pp. 165-173
    • Kim, V.N.1    Nam, J.W.2
  • 4
    • 77951972792 scopus 로고    scopus 로고
    • Regulation of MicroRNA Biogenesis: A miRiad of mechanisms
    • Davis BN Hata A. Regulation of MicroRNA Biogenesis: A miRiad of mechanisms. Cell Commun Signal 2009; 7: 18.
    • (2009) Cell Commun Signal , vol.7 , pp. 18
    • Davis, B.N.1    Hata, A.2
  • 6
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-97.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 7
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mRNAs are conserved targets of microRNAs
    • Friedman RC, Farh KK, Burge CB Bartel DP. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 2009; 19(1): 92-105.
    • (2009) Genome Res , vol.19 , Issue.1 , pp. 92-105
    • Friedman, R.C.1    Farh, K.K.2    Burge, C.B.3    Bartel, D.P.4
  • 8
    • 2442566370 scopus 로고    scopus 로고
    • Cytoplasmic foci are sites of mRNA decay in human cells
    • Cougot N, Babajko S Seraphin B. Cytoplasmic foci are sites of mRNA decay in human cells. J Cell Biol 2004; 165(1): 31-40.
    • (2004) J Cell Biol , vol.165 , Issue.1 , pp. 31-40
    • Cougot, N.1    Babajko, S.2    Seraphin, B.3
  • 9
    • 22144478256 scopus 로고    scopus 로고
    • MicroRNAdependent localization of targeted mRNAs to mammalian P-bodies
    • Liu J, Valencia-Sanchez MA, Hannon GJ Parker R. MicroRNAdependent localization of targeted mRNAs to mammalian P-bodies. Nat Cell Biol 2005; 7(7): 719-23.
    • (2005) Nat Cell Biol , vol.7 , Issue.7 , pp. 719-723
    • Liu, J.1    Valencia-Sanchez, M.A.2    Hannon, G.J.3    Parker, R.4
  • 10
    • 20444427566 scopus 로고    scopus 로고
    • Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies
    • Sen GL Blau HM. Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies. Nat Cell Biol 2005; 7(6): 633-6.
    • (2005) Nat Cell Biol , vol.7 , Issue.6 , pp. 633-636
    • Sen, G.L.1    Blau, H.M.2
  • 11
    • 56049121431 scopus 로고    scopus 로고
    • MicroRNA-mediated up-regulation of an alternatively polyadenylated variant of the mouse cytoplasmic {beta}-actin gene
    • Ghosh T, Soni K, Scaria V, Halimani M, Bhattacharjee C Pillai B. MicroRNA-mediated up-regulation of an alternatively polyadenylated variant of the mouse cytoplasmic {beta}-actin gene. Nucleic Acids Res 2008; 36(19): 6318-32.
    • (2008) Nucleic Acids Res , vol.36 , Issue.19 , pp. 6318-6332
    • Ghosh, T.1    Soni, K.2    Scaria, V.3    Halimani, M.4    Bhattacharjee, C.5    Pillai, B.6
  • 12
    • 36749026906 scopus 로고    scopus 로고
    • Switching from repression to activation: MicroRNAs can up-regulate translation
    • Vasudevan S, Tong Y Steitz JA. Switching from repression to activation: microRNAs can up-regulate translation. Science 2007; 318(5858): 1931-4.
    • (2007) Science , vol.318 , Issue.5858 , pp. 1931-1934
    • Vasudevan, S.1    Tong, Y.2    Steitz, J.A.3
  • 13
    • 13844294261 scopus 로고    scopus 로고
    • Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing
    • Kanellopoulou C, Muljo SA, Kung AL, et al. Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev 2005; 19(4): 489-501.
    • (2005) Genes Dev , vol.19 , Issue.4 , pp. 489-501
    • Kanellopoulou, C.1    Muljo, S.A.2    Kung, A.L.3
  • 14
    • 33646716847 scopus 로고    scopus 로고
    • The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles
    • Andl T, Murchison EP, Liu F, et al. The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles. Curr Biol 2006; 16(10): 1041-9.
    • (2006) Curr Biol , vol.16 , Issue.10 , pp. 1041-1049
    • Andl, T.1    Murchison, E.P.2    Liu, F.3
  • 15
    • 0242266620 scopus 로고    scopus 로고
    • Dicer is essential for mouse development
    • Bernstein E, Kim SY, Carmell MA, et al. Dicer is essential for mouse development. Nat Genet 2003; 35(3): 215-7.
    • (2003) Nat Genet , vol.35 , Issue.3 , pp. 215-217
    • Bernstein, E.1    Kim, S.Y.2    Carmell, M.A.3
  • 17
    • 33644499134 scopus 로고    scopus 로고
    • Cell-typespecific signatures of microRNAs on target mRNA expression
    • Sood P, Krek A, Zavolan M, Macino G Rajewsky N. Cell-typespecific signatures of microRNAs on target mRNA expression. Proc Natl Acad Sci USA 2006; 103(8): 2746-51.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.8 , pp. 2746-2751
    • Sood, P.1    Krek, A.2    Zavolan, M.3    Macino, G.4    Rajewsky, N.5
  • 18
  • 19
    • 39749140336 scopus 로고    scopus 로고
    • MicroRNA regulation of cell lineages in mouse and human embryonic stem cells
    • Ivey KN, Muth A, Arnold J, et al. MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. Cell Stem Cell 2008; 2(3): 219-29.
    • (2008) Cell Stem Cell , vol.2 , Issue.3 , pp. 219-229
    • Ivey, K.N.1    Muth, A.2    Arnold, J.3
  • 20
    • 31744432337 scopus 로고    scopus 로고
    • The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation
    • Chen JF, Mandel EM, Thomson JM, et al. The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet 2006; 38(2): 228-33.
    • (2006) Nat Genet , vol.38 , Issue.2 , pp. 228-233
    • Chen, J.F.1    Mandel, E.M.2    Thomson, J.M.3
  • 21
    • 0346727524 scopus 로고    scopus 로고
    • MicroRNAs modulate hematopoietic lineage differentiation
    • Chen CZ, Li L, Lodish HF Bartel DP. MicroRNAs modulate hematopoietic lineage differentiation. Science 2004; 303(5654): 83-6.
    • (2004) Science , vol.303 , Issue.5654 , pp. 83-86
    • Chen, C.Z.1    Li, L.2    Lodish, H.F.3    Bartel, D.P.4
  • 22
    • 40749111551 scopus 로고    scopus 로고
    • A skin microRNA promotes differentiation by repressing 'stemness'
    • Yi R, Poy MN, Stoffel M Fuchs E. A skin microRNA promotes differentiation by repressing 'stemness'. Nature 2008; 452(7184): 225-9.
    • (2008) Nature , vol.452 , Issue.7184 , pp. 225-229
    • Yi, R.1    Poy, M.N.2    Stoffel, M.3    Fuchs, E.4
  • 25
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • Reya T, Morrison SJ, Clarke MF Weissman IL. Stem cells, cancer, and cancer stem cells. Nature 2001; 414(6859): 105-11.
    • (2001) Nature , vol.414 , Issue.6859 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 26
    • 0014330153 scopus 로고
    • The in vivo life span of normal and preneoplastic mouse mammary glands: A serial transplantation study
    • Daniel CW, De Ome KB, Young JT, Blair PB Faulkin LJ, Jr. The in vivo life span of normal and preneoplastic mouse mammary glands: a serial transplantation study. Proc Natl Acad Sci USA 1968; 61(1): 53-60.
    • (1968) Proc Natl Acad Sci USA , vol.61 , Issue.1 , pp. 53-60
    • Daniel, C.W.1    De Ome, K.B.2    Young, J.T.3    Blair, P.B.4    Faulkin Jr., L.J.5
  • 27
    • 84965810273 scopus 로고
    • Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice
    • Deome KB, Faulkin LJ, Jr., Bern HA Blair PB. Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice. Cancer Res 1959; 19(5): 515-20.
    • (1959) Cancer Res , vol.19 , Issue.5 , pp. 515-520
    • Deome, K.B.1    Faulkin Jr., L.J.2    Bern, H.A.3    Blair, P.B.4
  • 28
    • 0015016052 scopus 로고
    • The influence of host and tissue age on life span and growth rate of serially transplanted mouse mammary gland
    • Young LJ, Medina D, DeOme KB, Daniel CW. The influence of host and tissue age on life span and growth rate of serially transplanted mouse mammary gland. Exp Gerontol 1971; 6(1): 49-56.
    • (1971) Exp Gerontol , vol.6 , Issue.1 , pp. 49-56
    • Young, L.J.1    Medina, D.2    DeOme, K.B.3    Daniel, C.W.4
  • 29
    • 30144433093 scopus 로고    scopus 로고
    • Generation of a functional mammary gland from a single stem cell
    • Shackleton M, Vaillant F, Simpson KJ, et al. Generation of a functional mammary gland from a single stem cell. Nature 2006; 439(7072): 84-8.
    • (2006) Nature , vol.439 , Issue.7072 , pp. 84-88
    • Shackleton, M.1    Vaillant, F.2    Simpson, K.J.3
  • 30
    • 30144432901 scopus 로고    scopus 로고
    • Purification and unique properties of mammary epithelial stem cells
    • Stingl J, Eirew P, Ricketson I, et al. Purification and unique properties of mammary epithelial stem cells. Nature 2006; 439(7079): 993-7.
    • (2006) Nature , vol.439 , Issue.7079 , pp. 993-997
    • Stingl, J.1    Eirew, P.2    Ricketson, I.3
  • 31
    • 34247398806 scopus 로고    scopus 로고
    • Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia
    • Moraes RC, Zhang X, Harrington N, et al. Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia. Development 2007; 134(6): 1231-42.
    • (2007) Development , vol.134 , Issue.6 , pp. 1231-1242
    • Moraes, R.C.1    Zhang, X.2    Harrington, N.3
  • 32
    • 35848955428 scopus 로고    scopus 로고
    • ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
    • Ginestier C, Hur MH, Charafe-Jauffret E, et al. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 2007; 1(5): 555-67.
    • (2007) Cell Stem Cell , vol.1 , Issue.5 , pp. 555-567
    • Ginestier, C.1    Hur, M.H.2    Charafe-Jauffret, E.3
  • 33
    • 68349130357 scopus 로고    scopus 로고
    • Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
    • Lim E, Vaillant F, Wu D, et al. Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers. Nat Med 2009; 15(8): 907-13.
    • (2009) Nat Med , vol.15 , Issue.8 , pp. 907-913
    • Lim, E.1    Vaillant, F.2    Wu, D.3
  • 34
    • 33847304124 scopus 로고    scopus 로고
    • CD34+ hematopoietic stem-progenitor cell microRNA expression and function: A circuit diagram of differentiation control
    • Georgantas RW, 3rd, Hildreth R, Morisot S, et al. CD34+ hematopoietic stem-progenitor cell microRNA expression and function: a circuit diagram of differentiation control. Proc Natl Acad Sci USA 2007; 104(8): 2750-5.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.8 , pp. 2750-2755
    • Georgantas III, R.W.1    Hildreth, R.2    Morisot, S.3
  • 35
    • 76649099166 scopus 로고    scopus 로고
    • A putative role for microRNA-205 in mammary epithelial cell progenitors
    • Greene SB, Gunaratne PH, Hammond SM Rosen JM. A putative role for microRNA-205 in mammary epithelial cell progenitors. J Cell Sci 2010; 123(Pt 4): 606-18.
    • (2010) J Cell Sci , vol.123 , Issue.PART 4 , pp. 606-618
    • Greene, S.B.1    Gunaratne, P.H.2    Hammond, S.M.3    Rosen, J.M.4
  • 36
    • 37249031072 scopus 로고    scopus 로고
    • A role for microRNAs in maintenance of mouse mammary epithelial progenitor cells
    • Ibarra I, Erlich Y, Muthuswamy SK, Sachidanandam R Hannon GJ. A role for microRNAs in maintenance of mouse mammary epithelial progenitor cells. Genes Dev 2007; 21(24): 3238-43.
    • (2007) Genes Dev , vol.21 , Issue.24 , pp. 3238-3243
    • Ibarra, I.1    Erlich, Y.2    Muthuswamy, S.K.3    Sachidanandam, R.4    Hannon, G.J.5
  • 37
    • 68049114782 scopus 로고    scopus 로고
    • Downregulation of miRNA- 200c links breast cancer stem cells with normal stem cells
    • Shimono Y, Zabala M, Cho RW, et al. Downregulation of miRNA- 200c links breast cancer stem cells with normal stem cells. Cell 2009; 138(3): 592-603.
    • (2009) Cell , vol.138 , Issue.3 , pp. 592-603
    • Shimono, Y.1    Zabala, M.2    Cho, R.W.3
  • 38
    • 1942435249 scopus 로고    scopus 로고
    • Micromanagers of gene expression: The potentially widespread influence of metazoan microRNAs
    • Bartel DP Chen CZ. Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nature Rev Genet 2004; 5: 396.
    • (2004) Nature Rev Genet , vol.5 , pp. 396
    • Bartel, D.P.1    Chen, C.Z.2
  • 39
    • 12144290519 scopus 로고    scopus 로고
    • Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
    • Calin GA, Sevignani C, Dumitru CD, et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci USA 2004; 101(9): 2999-3004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.9 , pp. 2999-3004
    • Calin, G.A.1    Sevignani, C.2    Dumitru, C.D.3
  • 40
    • 20444467290 scopus 로고    scopus 로고
    • A microRNA polycistron as a potential human oncogene
    • He L, Thomson JM, Hemann MT, et al. A microRNA polycistron as a potential human oncogene. Nature 2005; 435(7043): 828-33.
    • (2005) Nature , vol.435 , Issue.7043 , pp. 828-833
    • He, L.1    Thomson, J.M.2    Hemann, M.T.3
  • 41
    • 31944435282 scopus 로고    scopus 로고
    • Lack of BIC and microRNA miR-155 expression in primary cases of Burkitt lymphoma
    • Kluiver J, Haralambieva E, de Jong D, et al. Lack of BIC and microRNA miR-155 expression in primary cases of Burkitt lymphoma. Genes Chromosomes Cancer 2006; 45(2): 147-53.
    • (2006) Genes Chromosomes Cancer , vol.45 , Issue.2 , pp. 147-153
    • Kluiver, J.1    Haralambieva, E.2    de Jong, D.3
  • 42
    • 37549024511 scopus 로고    scopus 로고
    • MicroRNA expression profiling of human breast cancer identifies new markers of tumour subtype
    • Blenkiron C, Goldstein LD, Thorne NP, et al. MicroRNA expression profiling of human breast cancer identifies new markers of tumour subtype. Genome Biol 2007; 8(10): R214.
    • (2007) Genome Biol , vol.8 , Issue.10
    • Blenkiron, C.1    Goldstein, L.D.2    Thorne, N.P.3
  • 43
    • 27244433702 scopus 로고    scopus 로고
    • Real-time expression profiling of microRNA precursors in human cancer cell lines
    • Jiang J, Lee EJ, Gusev Y Schmittgen TD. Real-time expression profiling of microRNA precursors in human cancer cell lines. Nucleic Acids Res 2005; 33(17): 5394-403.
    • (2005) Nucleic Acids Res , vol.33 , Issue.17 , pp. 5394-5403
    • Jiang, J.1    Lee, E.J.2    Gusev, Y.3    Schmittgen, T.D.4
  • 44
    • 23844555119 scopus 로고    scopus 로고
    • MicroRNA gene expression deregulation in human breast cancer
    • Iorio MV, Ferracin M, Liu CG, et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res 2005; 65: 7065-70.
    • (2005) Cancer Res , vol.65 , pp. 7065-7070
    • Iorio, M.V.1    Ferracin, M.2    Liu, C.G.3
  • 45
    • 33748624597 scopus 로고    scopus 로고
    • Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies
    • Mattie MD, Benz CC, Bowers J, et al. Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies. Mol Cancer 2006;5:24.
    • (2006) Mol Cancer , vol.5 , pp. 24
    • Mattie, M.D.1    Benz, C.C.2    Bowers, J.3
  • 46
    • 34250843675 scopus 로고    scopus 로고
    • The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines
    • Adams BD, Furneaux H White BA. The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines. Mol Endocrinol 2007; 21(5): 1132-47.
    • (2007) Mol Endocrinol , vol.21 , Issue.5 , pp. 1132-1147
    • Adams, B.D.1    Furneaux, H.2    White, B.A.3
  • 47
    • 48549099077 scopus 로고    scopus 로고
    • miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer
    • Kondo N, Toyama T, Sugiura H, Fujii Y Yamashita H. miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer. Cancer Res 2008; 68(13): 5004-8.
    • (2008) Cancer Res , vol.68 , Issue.13 , pp. 5004-5008
    • Kondo, N.1    Toyama, T.2    Sugiura, H.3    Fujii, Y.4    Yamashita, H.5
  • 48
    • 57649174634 scopus 로고    scopus 로고
    • MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer
    • Zhao JJ, Lin J, Yang H, et al. MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer. J Biol Chem 2008; 283(45): 31079-86.
    • (2008) J Biol Chem , vol.283 , Issue.45 , pp. 31079-31086
    • Zhao, J.J.1    Lin, J.2    Yang, H.3
  • 49
    • 56449092072 scopus 로고    scopus 로고
    • MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1
    • Miller TE, Ghoshal K, Ramaswamy B, et al. MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1. J Biol Chem 2008; 283(44): 29897-903.
    • (2008) J Biol Chem , vol.283 , Issue.44 , pp. 29897-298903
    • Miller, T.E.1    Ghoshal, K.2    Ramaswamy, B.3
  • 50
    • 77952921840 scopus 로고    scopus 로고
    • MicroRNA Cluster 221-222 and Estrogen Receptor {alpha} Interactions in Breast Cancer
    • Di Leva G, Gasparini P, Piovan C, et al. MicroRNA Cluster 221-222 and Estrogen Receptor {alpha} Interactions in Breast Cancer. J Natl Cancer Inst 2010; 102(10): 706-21.
    • (2010) J Natl Cancer Inst , vol.102 , Issue.10 , pp. 706-721
    • Di Leva, G.1    Gasparini, P.2    Piovan, C.3
  • 51
    • 77949617195 scopus 로고    scopus 로고
    • An estrogen receptor alpha suppressor, microRNA-22, is downregulated in estrogen receptor alpha-positive human breast cancer cell lines and clinical samples
    • Xiong J, Yu D, Wei N, et al. An estrogen receptor alpha suppressor, microRNA-22, is downregulated in estrogen receptor alpha-positive human breast cancer cell lines and clinical samples. FEBS J 2010; 277(7): 1684-94.
    • (2010) FEBS J , vol.277 , Issue.7 , pp. 1684-1694
    • Xiong, J.1    Yu, D.2    Wei, N.3
  • 52
    • 44049100934 scopus 로고    scopus 로고
    • Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy
    • Li X, Lewis MT, Huang J, et al. Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst 2008; 100(9): 672-9.
    • (2008) J Natl Cancer Inst , vol.100 , Issue.9 , pp. 672-679
    • Li, X.1    Lewis, M.T.2    Huang, J.3
  • 53
    • 33845904383 scopus 로고    scopus 로고
    • The response of CD24(- /low)/CD44+ breast cancer-initiating cells to radiation
    • Phillips TM, McBride WH Pajonk F. The response of CD24(- /low)/CD44+ breast cancer-initiating cells to radiation. J Natl Cancer Inst 2006; 98(24): 1777-85.
    • (2006) J Natl Cancer Inst , vol.98 , Issue.24 , pp. 1777-1785
    • Phillips, T.M.1    McBride, W.H.2    Pajonk, F.3
  • 54
    • 49649085001 scopus 로고    scopus 로고
    • Identification of tumorinitiating cells in a p53-null mouse model of breast cancer
    • Zhang M, Behbod F, Atkinson RL, et al. Identification of tumorinitiating cells in a p53-null mouse model of breast cancer. Cancer Res 2008; 68(12): 4674-82.
    • (2008) Cancer Res , vol.68 , Issue.12 , pp. 4674-4682
    • Zhang, M.1    Behbod, F.2    Atkinson, R.L.3
  • 55
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • Lu J, Getz G, Miska EA, et al. MicroRNA expression profiles classify human cancers. Nature 2005; 435(7043): 834-8.
    • (2005) Nature , vol.435 , Issue.7043 , pp. 834-838
    • Lu, J.1    Getz, G.2    Miska, E.A.3
  • 56
    • 33144490646 scopus 로고    scopus 로고
    • A microRNA expression signature of human solid tumors defines cancer gene targets
    • Volinia S, Calin GA, Liu CG, et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 2006; 103(7): 2257-61.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.7 , pp. 2257-2261
    • Volinia, S.1    Calin, G.A.2    Liu, C.G.3
  • 58
    • 36849078711 scopus 로고    scopus 로고
    • Let-7 regulates self renewal and tumorigenicity of breast cancer cells
    • Yu F, Yao H, Zhu P, et al. let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell 2007; 131(6): 1109-23.
    • (2007) Cell , vol.131 , Issue.6 , pp. 1109-1123
    • Yu, F.1    Yao, H.2    Zhu, P.3
  • 59
    • 44649163918 scopus 로고    scopus 로고
    • A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
    • Burk U, Schubert J, Wellner U, et al. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep 2008; 9(6): 582-9.
    • (2008) EMBO Rep , vol.9 , Issue.6 , pp. 582-589
    • Burk, U.1    Schubert, J.2    Wellner, U.3
  • 60
    • 43049103824 scopus 로고    scopus 로고
    • The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
    • Gregory PA, Bert AG, Paterson EL, et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 2008; 10(5): 593-601.
    • (2008) Nat Cell Biol , vol.10 , Issue.5 , pp. 593-601
    • Gregory, P.A.1    Bert, A.G.2    Paterson, E.L.3
  • 61
    • 47249091921 scopus 로고    scopus 로고
    • The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
    • Korpal M, Lee ES, Hu G Kang Y. The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem 2008; 283(22): 14910-4.
    • (2008) J Biol Chem , vol.283 , Issue.22 , pp. 14910-14914
    • Korpal, M.1    Lee, E.S.2    Hu, G.3    Kang, Y.4
  • 62
    • 41649091906 scopus 로고    scopus 로고
    • The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
    • Park SM, Gaur AB, Lengyel E Peter ME. The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev 2008; 22(7): 894-907.
    • (2008) Genes Dev , vol.22 , Issue.7 , pp. 894-907
    • Park, S.M.1    Gaur, A.B.2    Lengyel, E.3    Peter, M.E.4
  • 63
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani SA, Guo W, Liao MJ, et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008; 133(4): 704-15.
    • (2008) Cell , vol.133 , Issue.4 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.J.3
  • 64
    • 73349099030 scopus 로고    scopus 로고
    • MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells
    • Iliopoulos D, Polytarchou C, Hatziapostolou M, et al. MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells. Sci Signal 2009; 2(92): ra62.
    • (2009) Sci Signal , vol.2 , Issue.92
    • Iliopoulos, D.1    Polytarchou, C.2    Hatziapostolou, M.3
  • 65
    • 73049110243 scopus 로고    scopus 로고
    • The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
    • Wellner U, Schubert J, Burk UC, et al. The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nat Cell Biol 2009; 11(12): 1487-95.
    • (2009) Nat Cell Biol , vol.11 , Issue.12 , pp. 1487-1495
    • Wellner, U.1    Schubert, J.2    Burk, U.C.3
  • 66
    • 0024344852 scopus 로고
    • Multiple proto-oncogene activations in avian leukosis virus-induced lymphomas: Evidence for stagespecific events
    • Clurman BE Hayward WS. Multiple proto-oncogene activations in avian leukosis virus-induced lymphomas: evidence for stagespecific events. Mol Cell Biol 1989; 9(6): 2657-64.
    • (1989) Mol Cell Biol , vol.9 , Issue.6 , pp. 2657-2664
    • Clurman, B.E.1    Hayward, W.S.2
  • 67
    • 34247584465 scopus 로고    scopus 로고
    • Requirement of bic/microRNA-155 for normal immune function
    • Rodriguez A, Vigorito E, Clare S, et al. Requirement of bic/microRNA-155 for normal immune function. Science 2007; 316(5824): 608-11.
    • (2007) Science , vol.316 , Issue.5824 , pp. 608-611
    • Rodriguez, A.1    Vigorito, E.2    Clare, S.3
  • 68
    • 0346727383 scopus 로고    scopus 로고
    • High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma
    • Metzler M, Wilda M, Busch K, Viehmann S Borkhardt A. High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma. Genes Chromosomes Cancer 2004; 39(2): 167-9.
    • (2004) Genes Chromosomes Cancer , vol.39 , Issue.2 , pp. 167-169
    • Metzler, M.1    Wilda, M.2    Busch, K.3    Viehmann, S.4    Borkhardt, A.5
  • 69
    • 77951026718 scopus 로고    scopus 로고
    • MicroRNA-155 Functions as an OncomiR in Breast Cancer by Targeting the Suppressor of Cytokine Signaling 1 Gene
    • Jiang S, Zhang HW, Lu MH, et al. MicroRNA-155 Functions as an OncomiR in Breast Cancer by Targeting the Suppressor of Cytokine Signaling 1 Gene. Cancer Res 2010; 70(8): 3119-27.
    • (2010) Cancer Res , vol.70 , Issue.8 , pp. 3119-3127
    • Jiang, S.1    Zhang, H.W.2    Lu, M.H.3
  • 70
    • 34047270440 scopus 로고    scopus 로고
    • Characterization of microRNA expression levels and their biological correlates in human cancer cell lines
    • Gaur A, Jewell DA, Liang Y, et al. Characterization of microRNA expression levels and their biological correlates in human cancer cell lines. Cancer Res 2007; 67(6): 2456-68.
    • (2007) Cancer Res , vol.67 , Issue.6 , pp. 2456-2468
    • Gaur, A.1    Jewell, D.A.2    Liang, Y.3
  • 71
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
    • Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST Patel T. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 2007; 133(2): 647-58.
    • (2007) Gastroenterology , vol.133 , Issue.2 , pp. 647-658
    • Meng, F.1    Henson, R.2    Wehbe-Janek, H.3    Ghoshal, K.4    Jacob, S.T.5    Patel, T.6
  • 72
    • 38149042783 scopus 로고    scopus 로고
    • Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells
    • Frankel LB, Christoffersen NR, Jacobsen A, Lindow M, Krogh A Lund AH. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J Biol Chem 2008; 283(2): 1026-33.
    • (2008) J Biol Chem , vol.283 , Issue.2 , pp. 1026-1033
    • Frankel, L.B.1    Christoffersen, N.R.2    Jacobsen, A.3    Lindow, M.4    Krogh, A.5    Lund, A.H.6
  • 73
    • 40249092910 scopus 로고    scopus 로고
    • MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
    • Zhu S, Wu H, Wu F, Nie D, Sheng S Mo YY. MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res 2008; 18(3): 350-9.
    • (2008) Cell Res , vol.18 , Issue.3 , pp. 350-359
    • Zhu, S.1    Wu, H.2    Wu, F.3    Nie, D.4    Sheng, S.5    Mo, Y.Y.6
  • 74
    • 34347266556 scopus 로고    scopus 로고
    • MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1)
    • Zhu S, Si ML, Wu H Mo YY. MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J Biol Chem 2007; 282(19): 14328-36.
    • (2007) J Biol Chem , vol.282 , Issue.19 , pp. 14328-14336
    • Zhu, S.1    Si, M.L.2    Wu, H.3    Mo, Y.Y.4
  • 75
    • 54249136806 scopus 로고    scopus 로고
    • MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells
    • Papagiannakopoulos T, Shapiro A Kosik KS. MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Res 2008; 68(19): 8164-72.
    • (2008) Cancer Res , vol.68 , Issue.19 , pp. 8164-8172
    • Papagiannakopoulos, T.1    Shapiro, A.2    Kosik, K.S.3
  • 76
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • Calin GA, Dumitru CD, Shimizu M, et al. Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 2002; 99(24): 15524-9.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.24 , pp. 15524-15529
    • Calin, G.A.1    Dumitru, C.D.2    Shimizu, M.3
  • 77
    • 42449152333 scopus 로고    scopus 로고
    • MiR-15a and miR-16-1 cluster functions in human leukemia
    • Calin GA, Cimmino A, Fabbri M, et al. MiR-15a and miR-16-1 cluster functions in human leukemia. Proc Natl Acad Sci USA 2008; 105(13): 5166-71.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.13 , pp. 5166-5171
    • Calin, G.A.1    Cimmino, A.2    Fabbri, M.3
  • 78
    • 33847738628 scopus 로고    scopus 로고
    • Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b
    • Scott GK, Goga A, Bhaumik D, Berger CE, Sullivan CS Benz CC. Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b. J Biol Chem 2007; 282(2): 1479-86.
    • (2007) J Biol Chem , vol.282 , Issue.2 , pp. 1479-1486
    • Scott, G.K.1    Goga, A.2    Bhaumik, D.3    Berger, C.E.4    Sullivan, C.S.5    Benz, C.C.6
  • 79
    • 66249089505 scopus 로고    scopus 로고
    • Germline mutation of microRNA-125a is associated with breast cancer
    • Li W, Duan R, Kooy F, Sherman SL, Zhou W Jin P. Germline mutation of microRNA-125a is associated with breast cancer. J Med Genet 2009; 46(5): 358-60.
    • (2009) J Med Genet , vol.46 , Issue.5 , pp. 358-360
    • Li, W.1    Duan, R.2    Kooy, F.3    Sherman, S.L.4    Zhou, W.5    Jin, P.6
  • 80
    • 65549110881 scopus 로고    scopus 로고
    • microRNA-205 regulates HER3 in human breast cancer
    • Iorio MV, Casalini P, Piovan C, et al. microRNA-205 regulates HER3 in human breast cancer. Cancer Res 2009; 69(6): 2195-200.
    • (2009) Cancer Res , vol.69 , Issue.6 , pp. 2195-2200
    • Iorio, M.V.1    Casalini, P.2    Piovan, C.3
  • 81
    • 64149089915 scopus 로고    scopus 로고
    • Suppression of cell growth and invasion by miR-205 in breast cancer
    • Wu H, Zhu S Mo YY. Suppression of cell growth and invasion by miR-205 in breast cancer. Cell Res 2009; 19(4): 439-48.
    • (2009) Cell Res , vol.19 , Issue.4 , pp. 439-448
    • Wu, H.1    Zhu, S.2    Mo, Y.Y.3
  • 82
    • 27544495514 scopus 로고    scopus 로고
    • A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation
    • Hayashita Y, Osada H, Tatematsu Y, et al. A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res 2005; 65(21): 9628-32.
    • (2005) Cancer Res , vol.65 , Issue.21 , pp. 9628-9632
    • Hayashita, Y.1    Osada, H.2    Tatematsu, Y.3
  • 83
    • 49749086530 scopus 로고    scopus 로고
    • A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation
    • Yu Z, Wang C, Wang M, et al. A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. J Cell Biol 2008; 182(3): 509-17.
    • (2008) J Cell Biol , vol.182 , Issue.3 , pp. 509-517
    • Yu, Z.1    Wang, C.2    Wang, M.3
  • 84
    • 34047264639 scopus 로고    scopus 로고
    • Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors
    • Woods K, Thomson JM Hammond SM. Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J Biol Chem 2007; 282(4): 2130-4.
    • (2007) J Biol Chem , vol.282 , Issue.4 , pp. 2130-2134
    • Woods, K.1    Thomson, J.M.2    Hammond, S.M.3
  • 85
    • 39849095077 scopus 로고    scopus 로고
    • E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer
    • Petrocca F, Visone R, Onelli MR, et al. E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer. Cancer Cell 2008; 13(3): 272-86.
    • (2008) Cancer Cell , vol.13 , Issue.3 , pp. 272-286
    • Petrocca, F.1    Visone, R.2    Onelli, M.R.3
  • 86
    • 39749143354 scopus 로고    scopus 로고
    • Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters
    • Ventura A, Young AG, Winslow MM, et al. Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell 2008; 132(5): 875-86.
    • (2008) Cell , vol.132 , Issue.5 , pp. 875-886
    • Ventura, A.1    Young, A.G.2    Winslow, M.M.3
  • 87
    • 33947426095 scopus 로고    scopus 로고
    • Translational repression of E2F1 mRNA in carcinoma in situ and normal testis correlates with expression of the miR-17-92 cluster
    • Novotny GW, Sonne SB, Nielsen JE, et al. Translational repression of E2F1 mRNA in carcinoma in situ and normal testis correlates with expression of the miR-17-92 cluster. Cell Death Differ 2007; 14(4): 879-82.
    • (2007) Cell Death Differ , vol.14 , Issue.4 , pp. 879-882
    • Novotny, G.W.1    Sonne, S.B.2    Nielsen, J.E.3
  • 88
    • 33750376591 scopus 로고    scopus 로고
    • Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AIB1 mRNA
    • Hossain A, Kuo MT Saunders GF. Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AIB1 mRNA. Mol Cell Biol 2006; 26(21): 8191-201.
    • (2006) Mol Cell Biol , vol.26 , Issue.21 , pp. 8191-8201
    • Hossain, A.1    Kuo, M.T.2    Saunders, G.F.3
  • 90
    • 74049112952 scopus 로고    scopus 로고
    • Characterisation of microRNA expression in post-natal mouse mammary gland development
    • Avril-Sassen S, Goldstein LD, Stingl J, et al. Characterisation of microRNA expression in post-natal mouse mammary gland development. BMC Genomics 2009; 10: 548.
    • (2009) BMC Genomics , vol.10 , pp. 548
    • Avril-Sassen, S.1    Goldstein, L.D.2    Stingl, J.3
  • 91
    • 68649113121 scopus 로고    scopus 로고
    • The p53 Pathway Encounters the MicroRNA World
    • Takwi A Li Y. The p53 Pathway Encounters the MicroRNA World. Curr Genomics 2009; 10(3): 194-7.
    • (2009) Curr Genomics , vol.10 , Issue.3 , pp. 194-197
    • Takwi, A.1    Li, Y.2
  • 92
    • 34250851115 scopus 로고    scopus 로고
    • A microRNA component of the p53 tumour suppressor network
    • He L, He X, Lim LP, et al. A microRNA component of the p53 tumour suppressor network. Nature 2007; 447(7148): 1130-4.
    • (2007) Nature , vol.447 , Issue.7148 , pp. 1130-1134
    • He, L.1    He, X.2    Lim, L.P.3
  • 93
    • 62549148270 scopus 로고    scopus 로고
    • p53 represses c-Myc through induction of the tumor suppressor miR-145
    • Sachdeva M, Zhu S, Wu F, et al. p53 represses c-Myc through induction of the tumor suppressor miR-145. Proc Natl Acad Sci USA 2009; 106(9): 3207-12.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.9 , pp. 3207-3212
    • Sachdeva, M.1    Zhu, S.2    Wu, F.3
  • 94
    • 58149215802 scopus 로고    scopus 로고
    • miR-29 miRNAs activate p53 by targeting p85 alpha and CDC42
    • Park SY, Lee JH, Ha M, Nam JW Kim VN. miR-29 miRNAs activate p53 by targeting p85 alpha and CDC42. Nat Struct Mol Biol 2009; 16(1): 23-9.
    • (2009) Nat Struct Mol Biol , vol.16 , Issue.1 , pp. 23-29
    • Park, S.Y.1    Lee, J.H.2    Ha, M.3    Nam, J.W.4    Kim, V.N.5
  • 95
    • 57749099102 scopus 로고    scopus 로고
    • p53-Responsive MicroRNAs 192 and 215 Are Capable of Inducing Cell Cycle Arrest
    • Braun CJ, Zhang X, Savelyeva I, et al. p53-Responsive MicroRNAs 192 and 215 Are Capable of Inducing Cell Cycle Arrest. Cancer Res 2009; 68(24): 10094-104.
    • (2009) Cancer Res , vol.68 , Issue.24 , pp. 10094-100104
    • Braun, C.J.1    Zhang, X.2    Savelyeva, I.3
  • 97
    • 70350233470 scopus 로고    scopus 로고
    • Metastamir: The field of metastasis-regulatory microRNA is spreading
    • Hurst DR, Edmonds MD Welch DR. Metastamir: the field of metastasis-regulatory microRNA is spreading. Cancer Res 2009; 69(19): 7495-8.
    • (2009) Cancer Res , vol.69 , Issue.19 , pp. 7495-7498
    • Hurst, D.R.1    Edmonds, M.D.2    Welch, D.R.3
  • 99
    • 70349645539 scopus 로고    scopus 로고
    • miR-200 enhances mouse breast cancer cell colonization to form distant metastases
    • Dykxhoorn DM, Wu Y, Xie H, et al. miR-200 enhances mouse breast cancer cell colonization to form distant metastases. PLoS ONE 2009; 4(9): e7181.
    • (2009) PLoS ONE , vol.4 , Issue.9
    • Dykxhoorn, D.M.1    Wu, Y.2    Xie, H.3
  • 100
    • 66849140943 scopus 로고    scopus 로고
    • MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents
    • [Epub ahead of print]
    • Cochrane DR, Spoelstra NS, Howe EN, Nordeen SK Richer JK. MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents. Mol Cancer Ther 2009 [Epub ahead of print].
    • (2009) Mol Cancer Ther
    • Cochrane, D.R.1    Spoelstra, N.S.2    Howe, E.N.3    Nordeen, S.K.4    Richer, J.K.5
  • 101
    • 77649275464 scopus 로고    scopus 로고
    • miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis
    • Ma L, Young J, Prabhala H, et al. miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol 2010; 12(3): 247-56.
    • (2010) Nat Cell Biol , vol.12 , Issue.3 , pp. 247-256
    • Ma, L.1    Young, J.2    Prabhala, H.3
  • 102
    • 70349258097 scopus 로고    scopus 로고
    • Breast cancer metastasis suppressor 1 coordinately regulates metastasis-associated microRNA expression
    • Edmonds MD, Hurst DR, Vaidya KS, Stafford LJ, Chen D Welch DR. Breast cancer metastasis suppressor 1 coordinately regulates metastasis-associated microRNA expression. Int J Cancer 2009; 125(8): 1778-85.
    • (2009) Int J Cancer , vol.125 , Issue.8 , pp. 1778-1785
    • Edmonds, M.D.1    Hurst, D.R.2    Vaidya, K.S.3    Stafford, L.J.4    Chen, D.5    Welch, D.R.6
  • 103
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
    • Ma L, Teruya-Feldstein J Weinberg RA. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 2007; 449(7163): 682-8.
    • (2007) Nature , vol.449 , Issue.7163 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weinberg, R.A.3
  • 104
    • 77954230727 scopus 로고    scopus 로고
    • miR-10b targets Tiam1: Implications for Rac activation and carcinoma migration
    • [Epub ahead of print]
    • Moriarty CH, Pursell B Mercurio AM. miR-10b targets Tiam1: Implications for Rac activation and carcinoma migration. J Biol Chem 2010 [Epub ahead of print].
    • (2010) J Biol Chem
    • Moriarty, C.H.1    Pursell, B.2    Mercurio, A.M.3
  • 105
    • 77950665077 scopus 로고    scopus 로고
    • Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model
    • Ma L, Reinhardt F, Pan E, et al. Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model. Nat Biotechnol 2010; 28(4): 341-7.
    • (2010) Nat Biotechnol , vol.28 , Issue.4 , pp. 341-347
    • Ma, L.1    Reinhardt, F.2    Pan, E.3
  • 106
    • 38049115129 scopus 로고    scopus 로고
    • Endogenous human microRNAs that suppress breast cancer metastasis
    • Tavazoie SF, Alarcon C, Oskarsson T, et al. Endogenous human microRNAs that suppress breast cancer metastasis. Nature 2008; 451(7175): 147-52.
    • (2008) Nature , vol.451 , Issue.7175 , pp. 147-152
    • Tavazoie, S.F.1    Alarcon, C.2    Oskarsson, T.3
  • 107
    • 54449099588 scopus 로고    scopus 로고
    • The cell growth suppressor, mir- 126, targets IRS-1
    • Zhang J, Du YY, Lin YF, et al. The cell growth suppressor, mir- 126, targets IRS-1. Biochem Biophys Res Commun 2008; 377(1): 136-40.
    • (2008) Biochem Biophys Res Commun , vol.377 , Issue.1 , pp. 136-140
    • Zhang, J.1    Du, Y.Y.2    Lin, Y.F.3
  • 108
    • 52149102044 scopus 로고    scopus 로고
    • Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells
    • Bhaumik D, Scott GK, Schokrpur S, Patil CK, Campisi J Benz CC. Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells. Oncogene 2008; 27(42): 5643-7.
    • (2008) Oncogene , vol.27 , Issue.42 , pp. 5643-5647
    • Bhaumik, D.1    Scott, G.K.2    Schokrpur, S.3    Patil, C.K.4    Campisi, J.5    Benz, C.C.6
  • 109
    • 66449095667 scopus 로고    scopus 로고
    • A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis
    • Valastyan S, Reinhardt F, Benaich N, et al. A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell 2009; 137(6): 1032-46.
    • (2009) Cell , vol.137 , Issue.6 , pp. 1032-1046
    • Valastyan, S.1    Reinhardt, F.2    Benaich, N.3
  • 110
    • 72749098126 scopus 로고    scopus 로고
    • Concomitant suppression of three target genes can explain the impact of a microRNA on metastasis
    • Valastyan S, Benaich N, Chang A, Reinhardt F Weinberg RA. Concomitant suppression of three target genes can explain the impact of a microRNA on metastasis. Genes Dev 2009; 23(22): 2592-7.
    • (2009) Genes Dev , vol.23 , Issue.22 , pp. 2592-2597
    • Valastyan, S.1    Benaich, N.2    Chang, A.3    Reinhardt, F.4    Weinberg, R.A.5
  • 111
    • 38849107424 scopus 로고    scopus 로고
    • The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis
    • Huang Q, Gumireddy K, Schrier M, et al. The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis. Nature Cell Biol 2008; 10(2): 202-10.
    • (2008) Nature Cell Biol , vol.10 , Issue.2 , pp. 202-210
    • Huang, Q.1    Gumireddy, K.2    Schrier, M.3
  • 112
    • 75149124701 scopus 로고    scopus 로고
    • MicroRNA-145 Suppresses cell invasion and metastasis by directly targeting mucin 1
    • Sachdeva M Mo YY. MicroRNA-145 Suppresses cell invasion and metastasis by directly targeting mucin 1. Cancer Res 2010; 70(1): 378-87.
    • (2010) Cancer Res , vol.70 , Issue.1 , pp. 378-387
    • Sachdeva, M.1    Mo, Y.Y.2
  • 113
    • 72249097073 scopus 로고    scopus 로고
    • Inhibition of rho-associated kinase signaling prevents breast cancer metastasis to human bone
    • Liu S, Goldstein RH, Scepansky EM Rosenblatt M. Inhibition of rho-associated kinase signaling prevents breast cancer metastasis to human bone. Cancer Res 2009; 69(22): 8742-51.
    • (2009) Cancer Res , vol.69 , Issue.22 , pp. 8742-8751
    • Liu, S.1    Goldstein, R.H.2    Scepansky, E.M.3    Rosenblatt, M.4
  • 114
    • 77952360640 scopus 로고    scopus 로고
    • microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling
    • Yu Z, Willmarth NE, Zhou J, et al. microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling. Proc Natl Acad Sci USA 2010; 107(18): 8231-6.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.18 , pp. 8231-8236
    • Yu, Z.1    Willmarth, N.E.2    Zhou, J.3
  • 115
    • 70349134366 scopus 로고    scopus 로고
    • MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets
    • Baffa R, Fassan M, Volinia S, et al. MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets. J Pathol 2009; 219(2): 214-21.
    • (2009) J Pathol , vol.219 , Issue.2 , pp. 214-221
    • Baffa, R.1    Fassan, M.2    Volinia, S.3
  • 116
    • 40949137731 scopus 로고    scopus 로고
    • Hsa-miR-210 Is induced by hypoxia and is an independent prognostic factor in breast cancer
    • Camps C, Buffa FM, Colella S, et al. hsa-miR-210 Is induced by hypoxia and is an independent prognostic factor in breast cancer. Clin Cancer Res 2008; 14(5): 1340-8.
    • (2008) Clin Cancer Res , vol.14 , Issue.5 , pp. 1340-1348
    • Camps, C.1    Buffa, F.M.2    Colella, S.3
  • 117
    • 59149091637 scopus 로고    scopus 로고
    • MicroRNA regulation of DNA repair gene expression in hypoxic stress
    • Crosby ME, Kulshreshtha R, Ivan M Glazer PM. MicroRNA regulation of DNA repair gene expression in hypoxic stress. Cancer Res 2009; 69(3): 1221-9.
    • (2009) Cancer Res , vol.69 , Issue.3 , pp. 1221-1229
    • Crosby, M.E.1    Kulshreshtha, R.2    Ivan, M.3    Glazer, P.M.4
  • 119
    • 51349103144 scopus 로고    scopus 로고
    • Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer
    • Foekens JA, Sieuwerts AM, Smid M, et al. Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer. Proc Natl Acad Sci USA 2008; 105(35): 13021-6.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.35 , pp. 13021-13026
    • Foekens, J.A.1    Sieuwerts, A.M.2    Smid, M.3
  • 120
    • 47049119934 scopus 로고    scopus 로고
    • MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3
    • Fasanaro P, D'Alessandra Y, Di Stefano V, et al. MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3. J Biol Chem 2008; 283(23): 15878-83.
    • (2008) J Biol Chem , vol.283 , Issue.23 , pp. 15878-15883
    • Fasanaro, P.1    D'Alessandra, Y.2    Di Stefano, V.3
  • 121
    • 70349478990 scopus 로고    scopus 로고
    • MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2
    • Chan SY, Zhang YY, Hemann C, Mahoney CE, Zweier JL Loscalzo J. MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2. Cell Metab 2009; 10(4): 273-84.
    • (2009) Cell Metab , vol.10 , Issue.4 , pp. 273-284
    • Chan, S.Y.1    Zhang, Y.Y.2    Hemann, C.3    Mahoney, C.E.4    Zweier, J.L.5    Loscalzo, J.6
  • 122
    • 77950799838 scopus 로고    scopus 로고
    • MicroRNA-519c suppresses hypoxia-inducible factor-1alpha expression and tumor angiogenesis
    • Cha ST, Chen PS, Johansson G, et al. MicroRNA-519c suppresses hypoxia-inducible factor-1alpha expression and tumor angiogenesis. Cancer Res. 2010; 70(7): 2675-85.
    • (2010) Cancer Res , vol.70 , Issue.7 , pp. 2675-2685
    • Cha, S.T.1    Chen, P.S.2    Johansson, G.3
  • 123
    • 54249117763 scopus 로고    scopus 로고
    • A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk
    • Chin LJ, Ratner E, Leng S, et al. A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. Cancer Res 2008; 68(20): 8535-40.
    • (2008) Cancer Res , vol.68 , Issue.20 , pp. 8535-8540
    • Chin, L.J.1    Ratner, E.2    Leng, S.3
  • 124
    • 70349682881 scopus 로고    scopus 로고
    • An miR-502-binding site singlenucleotide polymorphism in the 3'-untranslated region of the SET8 gene is associated with early age of breast cancer onset
    • Song F, Zheng H, Liu B, et al. An miR-502-binding site singlenucleotide polymorphism in the 3'-untranslated region of the SET8 gene is associated with early age of breast cancer onset. Clin Cancer Res 2009; 15(19): 6292-300.
    • (2009) Clin Cancer Res , vol.15 , Issue.19 , pp. 6292-6300
    • Song, F.1    Zheng, H.2    Liu, B.3
  • 125
    • 58949101499 scopus 로고    scopus 로고
    • A variant affecting a putative miRNA target site in estrogen receptor (ESR) 1 is associated with breast cancer risk in premenopausal women
    • Tchatchou S, Jung A, Hemminki K, et al. A variant affecting a putative miRNA target site in estrogen receptor (ESR) 1 is associated with breast cancer risk in premenopausal women. Carcinogenesis 2009; 30(1): 59-64.
    • (2009) Carcinogenesis , vol.30 , Issue.1 , pp. 59-64
    • Tchatchou, S.1    Jung, A.2    Hemminki, K.3
  • 126
    • 77950822671 scopus 로고    scopus 로고
    • Single-nucleotide polymorphisms inside microRNA target sites influence tumor susceptibility
    • Nicoloso MS, Sun H, Spizzo R, et al. Single-nucleotide polymorphisms inside microRNA target sites influence tumor susceptibility. Cancer Res 2010; 70(7): 2789-98.
    • (2010) Cancer Res , vol.70 , Issue.7 , pp. 2789-2798
    • Nicoloso, M.S.1    Sun, H.2    Spizzo, R.3
  • 127
    • 67650995908 scopus 로고    scopus 로고
    • MicroRNA miR-196a-2 and breast cancer: A genetic and epigenetic association study and functional analysis
    • Hoffman AE, Zheng T, Yi C, et al. microRNA miR-196a-2 and breast cancer: a genetic and epigenetic association study and functional analysis. Cancer Res 2009; 69(14): 5970-7.
    • (2009) Cancer Res , vol.69 , Issue.14 , pp. 5970-5977
    • Hoffman, A.E.1    Zheng, T.2    Yi, C.3
  • 128
    • 77953122376 scopus 로고    scopus 로고
    • A genetic variant in the pre-miR-27a oncogene is associated with a reduced familial breast cancer risk
    • Yang R, Schlehe B, Hemminki K, et al. A genetic variant in the pre-miR-27a oncogene is associated with a reduced familial breast cancer risk. Breast Cancer Res Treat 2010; 121(3): 693-702.
    • (2010) Breast Cancer Res Treat , vol.121 , Issue.3 , pp. 693-702
    • Yang, R.1    Schlehe, B.2    Hemminki, K.3
  • 130
    • 1242318826 scopus 로고    scopus 로고
    • Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing
    • Meister G, Landthaler M, Dorsett Y, Tuschl T. Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing. RNA 2004; 10(3): 544-50.
    • (2004) RNA , vol.10 , Issue.3 , pp. 544-550
    • Meister, G.1    Landthaler, M.2    Dorsett, Y.3    Tuschl, T.4
  • 131
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan JA, Krichevsky AM, Kosik KS. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 2005; 65(14): 6029-33.
    • (2005) Cancer Res , vol.65 , Issue.14 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 132
    • 33646027887 scopus 로고    scopus 로고
    • LNA-modified oligonucleotides mediate specific inhibition of microRNA function
    • Orom UA, Kauppinen S, Lund AH. LNA-modified oligonucleotides mediate specific inhibition of microRNA function. Gene 2006; 372: 137-41.
    • (2006) Gene , vol.372 , pp. 137-141
    • Orom, U.A.1    Kauppinen, S.2    Lund, A.H.3
  • 133
    • 0034625010 scopus 로고    scopus 로고
    • Potent and nontoxic antisense oligonucleotides containing locked nucleic acids
    • Wahlestedt C, Salmi P, Good L, et al. Potent and nontoxic antisense oligonucleotides containing locked nucleic acids. Proc Natl Acad Sci USA 2000; 97(10): 5633-8.
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.10 , pp. 5633-5638
    • Wahlestedt, C.1    Salmi, P.2    Good, L.3
  • 134
    • 28444469246 scopus 로고    scopus 로고
    • Silencing of microRNAs in vivo with 'antagomirs'
    • Krutzfeldt J, Rajewsky N, Braich R, et al. Silencing of microRNAs in vivo with 'antagomirs'. Nature 2005; 438(7068): 685-9.
    • (2005) Nature , vol.438 , Issue.7068 , pp. 685-689
    • Krutzfeldt, J.1    Rajewsky, N.2    Braich, R.3
  • 135
    • 34250679405 scopus 로고    scopus 로고
    • Specificity, duplex degradation and subcellular localization of antagomirs
    • Krutzfeldt J, Kuwajima S, Braich R, et al. Specificity, duplex degradation and subcellular localization of antagomirs. Nucleic Acids Res 2007; 35(9): 2885-92.
    • (2007) Nucleic Acids Res , vol.35 , Issue.9 , pp. 2885-2892
    • Krutzfeldt, J.1    Kuwajima, S.2    Braich, R.3
  • 136
    • 48249098902 scopus 로고    scopus 로고
    • Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM
    • Fontana L, Fiori ME, Albini S, et al. Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM. PLoS ONE 2008; 3(5): e2236.
    • (2008) PLoS ONE , vol.3 , Issue.5
    • Fontana, L.1    Fiori, M.E.2    Albini, S.3
  • 137
    • 57749168828 scopus 로고    scopus 로고
    • MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
    • Thum T, Gross C, Fiedler J, et al. MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature 2008; 456(7224): 980-4.
    • (2008) Nature , vol.456 , Issue.7224 , pp. 980-984
    • Thum, T.1    Gross, C.2    Fiedler, J.3
  • 138
    • 66349123063 scopus 로고    scopus 로고
    • MicroRNA-320 is involved in the regulation of cardiac ischemia/reperfusion injury by targeting heatshock protein 20
    • Ren XP, Wu J, Wang X, et al. MicroRNA-320 is involved in the regulation of cardiac ischemia/reperfusion injury by targeting heatshock protein 20. Circulation 2009; 119(17): 2357-66.
    • (2009) Circulation , vol.119 , Issue.17 , pp. 2357-2366
    • Ren, X.P.1    Wu, J.2    Wang, X.3
  • 139
    • 34249279050 scopus 로고    scopus 로고
    • MicroRNA-133 controls cardiac hypertrophy
    • May
    • Care A, Catalucci D, Felicetti F, et al. MicroRNA-133 controls cardiac hypertrophy. Nat Med 2007 May; 13(5): 613-8.
    • (2007) Nat Med , vol.13 , Issue.5 , pp. 613-618
    • Care, A.1    Catalucci, D.2    Felicetti, F.3
  • 141
    • 51349141401 scopus 로고    scopus 로고
    • Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis
    • van Rooij E, Sutherland LB, Thatcher JE, et al. Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc Natl Acad Sci USA 2008; 105(35): 13027-32.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.35 , pp. 13027-13032
    • van Rooij, E.1    Sutherland, L.B.2    Thatcher, J.E.3
  • 142
    • 20044395613 scopus 로고    scopus 로고
    • RAS is regulated by the let-7 microRNA family
    • Johnson SM, Grosshans H, Shingara J, et al. RAS is regulated by the let-7 microRNA family. Cell 2005; 120(5): 635-47.
    • (2005) Cell , vol.120 , Issue.5 , pp. 635-647
    • Johnson, S.M.1    Grosshans, H.2    Shingara, J.3
  • 143
    • 34247593034 scopus 로고    scopus 로고
    • Impaired microRNA processing enhances cellular transformation and tumorigenesis
    • Kumar MS, Lu J, Mercer KL, Golub TR Jacks T. Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet 2007; 39(5): 673-7.
    • (2007) Nat Genet , vol.39 , Issue.5 , pp. 673-677
    • Kumar, M.S.1    Lu, J.2    Mercer, K.L.3    Golub, T.R.4    Jacks, T.5
  • 144
    • 34247565615 scopus 로고    scopus 로고
    • The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
    • Lee YS Dutta A. The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev 2007; 21(9): 1025-30.
    • (2007) Genes Dev , vol.21 , Issue.9 , pp. 1025-1030
    • Lee, Y.S.1    Dutta, A.2
  • 145
    • 34548012848 scopus 로고    scopus 로고
    • The let-7 microRNA represses cell proliferation pathways in human cells
    • Johnson CD, Esquela-Kerscher A, Stefani G, et al. The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res 2007; 67(16): 7713-22.
    • (2007) Cancer Res , vol.67 , Issue.16 , pp. 7713-7722
    • Johnson, C.D.1    Esquela-Kerscher, A.2    Stefani, G.3
  • 146
    • 42049103216 scopus 로고    scopus 로고
    • The let-7 microRNA reduces tumor growth in mouse models of lung cancer
    • Esquela-Kerscher A, Trang P, Wiggins JF, et al. The let-7 microRNA reduces tumor growth in mouse models of lung cancer. Cell Cycle 2008; 7(6): 759-64.
    • (2008) Cell Cycle , vol.7 , Issue.6 , pp. 759-764
    • Esquela-Kerscher, A.1    Trang, P.2    Wiggins, J.F.3
  • 147
    • 38349190243 scopus 로고    scopus 로고
    • MicroRNAs modulate the chemosensitivity of tumor cells
    • Blower PE, Chung JH, Verducci JS, et al. MicroRNAs modulate the chemosensitivity of tumor cells. Mol Cancer Ther 2008; 7(1): 1-9.
    • (2008) Mol Cancer Ther , vol.7 , Issue.1 , pp. 1-9
    • Blower, P.E.1    Chung, J.H.2    Verducci, J.S.3
  • 148
    • 77956995581 scopus 로고    scopus 로고
    • Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin
    • [Epub ahead of print]
    • Pogribny IP, Filkowski JN, Tryndyak VP, Golubov A, Shpyleva SI Kovalchuk O. Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin. Int J Cancer 2010 [Epub ahead of print].
    • (2010) Int J Cancer
    • Pogribny, I.P.1    Filkowski, J.N.2    Tryndyak, V.P.3    Golubov, A.4    Shpyleva, S.I.5    Kovalchuk, O.6
  • 149
    • 46249092601 scopus 로고    scopus 로고
    • Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites
    • Sandberg R, Neilson JR, Sarma A, Sharp PA Burge CB. Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites. Science 2008; 320(5883): 1643-7.
    • (2008) Science , vol.320 , Issue.5883 , pp. 1643-1647
    • Sandberg, R.1    Neilson, J.R.2    Sarma, A.3    Sharp, P.A.4    Burge, C.B.5
  • 150
    • 68749113985 scopus 로고    scopus 로고
    • Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
    • Mayr C Bartel DP. Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells. Cell 2009; 138(4): 673-84.
    • (2009) Cell , vol.138 , Issue.4 , pp. 673-684
    • Mayr, C.1    Bartel, D.P.2
  • 151
    • 0037478605 scopus 로고    scopus 로고
    • Repeated observation of breast tumor subtypes in independent gene expression data sets
    • Sorlie T, Tibshirani R, Parker J, et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci USA 2003; 100(14): 8418-23.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.14 , pp. 8418-8423
    • Sorlie, T.1    Tibshirani, R.2    Parker, J.3
  • 152
    • 37548999684 scopus 로고    scopus 로고
    • Altered MicroRNA expression confined to specific epithelial cell subpopulations in breast cancer
    • Sempere LF, Christensen M, Silahtaroglu A, et al. Altered MicroRNA expression confined to specific epithelial cell subpopulations in breast cancer. Cancer Res 2007; 67(24): 11612-20.
    • (2007) Cancer Res , vol.67 , Issue.24 , pp. 11612-11620
    • Sempere, L.F.1    Christensen, M.2    Silahtaroglu, A.3
  • 153
    • 25444520537 scopus 로고    scopus 로고
    • miR-15 and miR-16 induce apoptosis by targeting BCL2
    • Cimmino A, Calin GA, Fabbri M, et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA 2005; 102(39): 13944-9.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.39 , pp. 13944-13949
    • Cimmino, A.1    Calin, G.A.2    Fabbri, M.3
  • 154
    • 55549114664 scopus 로고    scopus 로고
    • The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities
    • Bonci D, Coppola V, Musumeci M, et al. The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. Nat Med 2008; 14(11): 1271-7.
    • (2008) Nat Med , vol.14 , Issue.11 , pp. 1271-1277
    • Bonci, D.1    Coppola, V.2    Musumeci, M.3
  • 155
    • 34548687035 scopus 로고    scopus 로고
    • mir-29 regulates Mcl-1 protein expression and apoptosis
    • Mott JL, Kobayashi S, Bronk SF Gores GJ. mir-29 regulates Mcl-1 protein expression and apoptosis. Oncogene 2007; 26(42): 6133-40.
    • (2007) Oncogene , vol.26 , Issue.42 , pp. 6133-6140
    • Mott, J.L.1    Kobayashi, S.2    Bronk, S.F.3    Gores, G.J.4
  • 156
    • 33846190181 scopus 로고    scopus 로고
    • Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181
    • Pekarsky Y, Santanam U, Cimmino A, et al. Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181. Cancer Res 2006; 66(24): 11590-3.
    • (2006) Cancer Res , vol.66 , Issue.24 , pp. 11590-11593
    • Pekarsky, Y.1    Santanam, U.2    Cimmino, A.3
  • 157
    • 35649020283 scopus 로고    scopus 로고
    • MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
    • Fabbri M, Garzon R, Cimmino A, et al. MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc Natl Acad Sci USA 2007; 104(40): 15805-10.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.40 , pp. 15805-15810
    • Fabbri, M.1    Garzon, R.2    Cimmino, A.3
  • 158
    • 68949198148 scopus 로고    scopus 로고
    • MiR-107 and MiR-185 can induce cell cycle arrest in human non small cell lung cancer cell lines
    • Takahashi Y, Forrest AR, Maeno E, Hashimoto T, Daub CO, Yasuda J. MiR-107 and MiR-185 can induce cell cycle arrest in human non small cell lung cancer cell lines. PLoS ONE 2009; 4(8): e6677.
    • (2009) PLoS ONE , vol.4 , Issue.8
    • Takahashi, Y.1    Forrest, A.R.2    Maeno, E.3    Hashimoto, T.4    Daub, C.O.5    Yasuda, J.6
  • 159
    • 48749130187 scopus 로고    scopus 로고
    • miR-126 regulates angiogenic signaling and vascular integrity
    • Fish JE, Santoro MM, Morton SU, et al. miR-126 regulates angiogenic signaling and vascular integrity. Developmental Cell 2008; 15(2): 272-84.
    • (2008) Developmental Cell , vol.15 , Issue.2 , pp. 272-284
    • Fish, J.E.1    Santoro, M.M.2    Morton, S.U.3
  • 160
    • 38949193234 scopus 로고    scopus 로고
    • Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5
    • Chen Y, Gorski DH. Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5. Blood 2008; 111(3): 1217-26.
    • (2008) Blood , vol.111 , Issue.3 , pp. 1217-1226
    • Chen, Y.1    Gorski, D.H.2
  • 162
    • 10344243662 scopus 로고    scopus 로고
    • MicroRNA-143 regulates adipocyte differentiation
    • Esau C, Kang X, Peralta E, et al. MicroRNA-143 regulates adipocyte differentiation. J Biol Chem 2004; 279(50): 52361-5.
    • (2004) J Biol Chem , vol.279 , Issue.50 , pp. 52361-52365
    • Esau, C.1    Kang, X.2    Peralta, E.3
  • 163
    • 60549090858 scopus 로고    scopus 로고
    • Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis
    • Hurst DR, Edmonds MD, Scott GK, Benz CC, Vaidya KS Welch DR. Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis. Cancer Res 2009; 69(4): 1279-83.
    • (2009) Cancer Res , vol.69 , Issue.4 , pp. 1279-1283
    • Hurst, D.R.1    Edmonds, M.D.2    Scott, G.K.3    Benz, C.C.4    Vaidya, K.S.5    Welch, D.R.6
  • 164
    • 46449092527 scopus 로고    scopus 로고
    • A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis
    • Labbaye C, Spinello I, Quaranta MT, et al. A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis. Nat Cell Biol 2008; 10(7): 788-801.
    • (2008) Nat Cell Biol , vol.10 , Issue.7 , pp. 788-801
    • Labbaye, C.1    Spinello, I.2    Quaranta, M.T.3
  • 165
    • 33747608638 scopus 로고    scopus 로고
    • NF-kappaBdependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
    • Taganov KD, Boldin MP, Chang KJ Baltimore D. NF-kappaBdependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci USA 2006; 103(33): 12481-6.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.33 , pp. 12481-12486
    • Taganov, K.D.1    Boldin, M.P.2    Chang, K.J.3    Baltimore, D.4
  • 166
    • 30044436911 scopus 로고    scopus 로고
    • The role of microRNA genes in papillary thyroid carcinoma
    • He H, Jazdzewski K, Li W, et al. The role of microRNA genes in papillary thyroid carcinoma. Proc Natl Acad Sci USA 2005; 102(52): 19075-80.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.52 , pp. 19075-19080
    • He, H.1    Jazdzewski, K.2    Li, W.3
  • 167
    • 52449090510 scopus 로고    scopus 로고
    • c-Myb is an evolutionary conserved miR-150 target and miR-150/c-Myb interaction is important for embryonic development
    • Lin YC, Kuo MW, Yu J, et al. c-Myb is an evolutionary conserved miR-150 target and miR-150/c-Myb interaction is important for embryonic development. Mol Biol Evol 2008; 25(10): 2189-98.
    • (2008) Mol Biol Evol , vol.25 , Issue.10 , pp. 2189-2198
    • Lin, Y.C.1    Kuo, M.W.2    Yu, J.3
  • 168
    • 60549112361 scopus 로고    scopus 로고
    • Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor
    • Segura MF, Hanniford D, Menendez S, et al. Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor. Proc Natl Acad Sci USA 2009; 106(6): 1814-9.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.6 , pp. 1814-1819
    • Segura, M.F.1    Hanniford, D.2    Menendez, S.3
  • 169
    • 65549115615 scopus 로고    scopus 로고
    • miR-205 Exerts tumorsuppressive functions in human prostate through down-regulation of protein kinase Cepsilon
    • Gandellini P, Folini M, Longoni N, et al. miR-205 Exerts tumorsuppressive functions in human prostate through down-regulation of protein kinase Cepsilon. Cancer Res 2009; 69(6): 2287-95.
    • (2009) Cancer Res , vol.69 , Issue.6 , pp. 2287-2295
    • Gandellini, P.1    Folini, M.2    Longoni, N.3
  • 170
    • 71749100911 scopus 로고    scopus 로고
    • An integrated approach for experimental target identification of hypoxia-induced miR-210
    • Fasanaro P, Greco S, Lorenzi M, et al. An integrated approach for experimental target identification of hypoxia-induced miR-210. J Biol Chem 2009; 284(50): 35134-43.
    • (2009) J Biol Chem , vol.284 , Issue.50 , pp. 35134-35143
    • Fasanaro, P.1    Greco, S.2    Lorenzi, M.3
  • 171
    • 60549117656 scopus 로고    scopus 로고
    • Microtranscriptome regulation by gonadotropin-releasing hormone
    • Yuen T, Ruf F, Chu T Sealfon SC. Microtranscriptome regulation by gonadotropin-releasing hormone. Mol Cell Endocrinol 2009; 302(1): 12-7.
    • (2009) Mol Cell Endocrinol , vol.302 , Issue.1 , pp. 12-17
    • Yuen, T.1    Ruf, F.2    Chu, T.3    Sealfon, S.C.4
  • 172
    • 39049086391 scopus 로고    scopus 로고
    • MicroRNA expression profiling in human ovarian cancer: MiR-214 induces cell survival and cisplatin resistance by targeting PTEN
    • Yang H, Kong W, He L, et al. MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN. Cancer Res 2008; 68(2): 425-33.
    • (2008) Cancer Res , vol.68 , Issue.2 , pp. 425-433
    • Yang, H.1    Kong, W.2    He, L.3
  • 173
    • 67651045805 scopus 로고    scopus 로고
    • MicroRNA-373 (miR-373) post-transcriptionally regulates large tumor suppressor, homolog 2 (LATS2) and stimulates proliferation in hu/man esophageal cancer
    • Lee KH, Goan YG, Hsiao M, et al. MicroRNA-373 (miR-373) post-transcriptionally regulates large tumor suppressor, homolog 2 (LATS2) and stimulates proliferation in hu/man esophageal cancer. Exp Cell Res 2009; 315(15): 2529-38.
    • (2009) Exp Cell Res , vol.315 , Issue.15 , pp. 2529-2538
    • Lee, K.H.1    Goan, Y.G.2    Hsiao, M.3


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