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Volumn 69, Issue 22, 2009, Pages 8742-8751

Inhibition of Rho-associated kinase signaling prevents breast cancer metastasis to human bone

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ACTIN; MICRORNA; MYC PROTEIN; MYOSIN; RHO KINASE; SMALL INTERFERING RNA;

EID: 72249097073     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-1541     Document Type: Article
Times cited : (233)

References (50)
  • 1
    • 54849186600 scopus 로고    scopus 로고
    • The expression and prognostic value of ROCK I and ROCK II and their role in human breast cancer
    • Lane J, Martin TA, Watkins G, et al. The expression and prognostic value of ROCK I and ROCK II and their role in human breast cancer. Int J Oncol 2008;33:585-593
    • (2008) Int J Oncol , vol.33 , pp. 585-593
    • Lane, J.1    Martin, T.A.2    Watkins, G.3
  • 2
    • 0032812619 scopus 로고    scopus 로고
    • Rho-kinase (ROK) promotes CD44v(3,8-10)-ankyrin interaction and tumor cell migration in metastatic breast cancer cells
    • Bourguignon LY, Zhu H, Shao L, et al. Rho-kinase (ROK) promotes CD44v(3,8-10)-ankyrin interaction and tumor cell migration in metastatic breast cancer cells. Cell Motil Cytoskeleton 1999;43:269-287
    • (1999) Cell Motil Cytoskeleton , vol.43 , pp. 269-287
    • Bourguignon, L.Y.1    Zhu, H.2    Shao, L.3
  • 3
    • 33745861998 scopus 로고    scopus 로고
    • Involvement of Rho/ROCK signalling in small cell lung cancer migration through human brain microvascular endothelial cells
    • DOI 10.1016/j.febslet.2006.06.056, PII S0014579306007733
    • Li B, Zhao WD, Tan ZM, et al. Involvement of Rho/ ROCK signalling in small cell lung cancer migration through human brain microvascular endothelial cells. FEBS Lett 2006;580:4252-4260 (Pubitemid 44037578)
    • (2006) FEBS Letters , vol.580 , Issue.17 , pp. 4252-4260
    • Li, B.1    Zhao, W.-D.2    Tan, Z.-M.3    Fang, W.-G.4    Zhu, L.5    Chen, Y.-H.6
  • 5
    • 33746562929 scopus 로고    scopus 로고
    • ROCK- And Myosin-Dependent Matrix Deformation Enables Protease-Independent Tumor-Cell Invasion in Vivo
    • DOI 10.1016/j.cub.2006.05.065, PII S0960982206017246
    • Wyckoff JB, Pinner SE, Gschmeissner S, et al. ROCKand myosin-dependent matrix deformation enables protease-independent tumor-cell invasion in vivo. Curr Biol 2006;16:1515-1523 (Pubitemid 44142977)
    • (2006) Current Biology , vol.16 , Issue.15 , pp. 1515-1523
    • Wyckoff, J.B.1    Pinner, S.E.2    Gschmeissner, S.3    Condeelis, J.S.4    Sahai, E.5
  • 6
    • 41949102707 scopus 로고    scopus 로고
    • miRiad roles for the miR-17-92 cluster in development and disease
    • Mendell JT. miRiad roles for the miR-17-92 cluster in development and disease. Cell 2008;133:217-222
    • (2008) Cell , vol.133 , pp. 217-222
    • Mendell, J.T.1
  • 9
    • 2342449399 scopus 로고    scopus 로고
    • Identification and Characterization of a Novel Gene, C13orf25, as a Target for 13q31-q32 Amplification in Malignant Lymphoma
    • DOI 10.1158/0008-5472.CAN-03-3773
    • Ota A, Tagawa H, Karnan S, et al. Identification and characterization of a novel gene, C13orf25, as a target for 13q31-32 amplification in malignant lymphoma. Cancer Res 2004;64:3087-3095 (Pubitemid 38581408)
    • (2004) Cancer Research , vol.64 , Issue.9 , pp. 3087-3095
    • Ota, A.1    Tagawa, H.2    Karnan, S.3    Tsuzuki, S.4    Karpas, A.5    Kira, S.6    Yoshida, Y.7    Seto, M.8
  • 10
    • 20444467290 scopus 로고    scopus 로고
    • A microRNA polycistron as a potential human oncogene
    • He L, Thomson JM, Hemann MT, et al. A microRNA polycistron as a potential human oncogene. Nature 2005;435:828-833
    • (2005) Nature , vol.435 , pp. 828-833
    • He, L.1    Thomson, J.M.2    Hemann, M.T.3
  • 13
    • 34347218991 scopus 로고    scopus 로고
    • In vitro scratch assay: A convenient and inexpensive method for analysis of cell migration in vitro
    • Liang CC, Park AY, Guan JL. In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro. Nat Protoc 2007;2:329-333
    • (2007) Nat Protoc , vol.2 , pp. 329-333
    • Liang, C.C.1    Park, A.Y.2    Guan, J.L.3
  • 14
    • 38349064711 scopus 로고    scopus 로고
    • MicroRNA-134 modulates the differentiation of mouse embryonic stem cells, where it causes post-transcriptional attenuation of Nanog and LRH1
    • Tay YM, Tam WL, Ang YS, et al. MicroRNA-134 modulates the differentiation of mouse embryonic stem cells, where it causes post-transcriptional attenuation of Nanog and LRH1. Stem Cells 2008;26:17-29.
    • (2008) Stem Cells , vol.26 , pp. 17-29
    • Tay, Y.M.1    Tam, W.L.2    Ang, Y.S.3
  • 15
    • 48249098902 scopus 로고    scopus 로고
    • Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM
    • Fontana L, Fiori ME, Albini S, et al. Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM. PLoS ONE 2008;3:e2236.
    • (2008) PLoS ONE , vol.3
    • Fontana, L.1    Fiori, M.E.2    Albini, S.3
  • 18
    • 51249094266 scopus 로고    scopus 로고
    • Haem-regulated eIF2α kinase is necessary for adaptive gene expression in erythroid precursors under the stress of iron deficiency
    • Liu S, Bhattacharya S, Han A, et al. Haem-regulated eIF2α kinase is necessary for adaptive gene expression in erythroid precursors under the stress of iron deficiency. Br J Haematol 2008;143:129-137
    • (2008) Br J Haematol , vol.143 , pp. 129-137
    • Liu, S.1    Bhattacharya, S.2    Han, A.3
  • 20
    • 0038024241 scopus 로고    scopus 로고
    • Rocks: Multifunctional kinases in cell behaviour
    • DOI 10.1038/nrm1128
    • Riento K, Ridley AJ. Rocks: multifunctional kinases in cell behaviour. Nat Rev Mol Cell Biol 2003;4:446-456 (Pubitemid 36648590)
    • (2003) Nature Reviews Molecular Cell Biology , vol.4 , Issue.6 , pp. 446-456
    • Riento, K.1    Ridley, A.J.2
  • 21
    • 43249129458 scopus 로고    scopus 로고
    • MYH9-siRNA and MYH9 mutant alleles: Expression in cultured cell lines and their effects upon cell structure and function
    • DOI 10.1002/cm.20268
    • Li Y, Friedmann DR, Mhatre AN, et al. MYH9-siRNA and MYH9 mutant alleles: expression in cultured cell lines and their effects upon cell structure and function. Cell Motil Cytoskeleton 2008;65:393-405. (Pubitemid 351657154)
    • (2008) Cell Motility and the Cytoskeleton , vol.65 , Issue.5 , pp. 393-405
    • Li, Y.1    Friedmann, D.R.2    Mhatre, A.N.3    Lalwani, A.K.4
  • 23
    • 33750289641 scopus 로고    scopus 로고
    • ROCK signaling mediates the adoption of different modes of migration and invasion in human mammary epithelial tumor cells
    • DOI 10.1016/j.yexcr.2006.08.025, PII S0014482706003375
    • Torka R, Thuma F, Herzog V, et al. ROCK signaling mediates the adoption of different modes of migration and invasion in human mammary epithelial tumor cells. Exp Cell Res 2006;312:3857-3871 (Pubitemid 44633886)
    • (2006) Experimental Cell Research , vol.312 , Issue.19 , pp. 3857-3871
    • Torka, R.1    Thuma, F.2    Herzog, V.3    Kirfel, G.4
  • 24
    • 51849115992 scopus 로고    scopus 로고
    • The Rho-Rock-myosin signaling axis determines cell-cell integrity of selfrenewing pluripotent stem cells
    • Harb N, Archer TK, Sato N. The Rho-Rock-myosin signaling axis determines cell-cell integrity of selfrenewing pluripotent stem cells. PLoS ONE 2008;3:e3001.
    • (2008) PLoS ONE , vol.3
    • Harb, N.1    Archer, T.K.2    Sato, N.3
  • 25
    • 34250893239 scopus 로고    scopus 로고
    • Transcriptomal profiling of the cellular transformation induced by Rho subfamily GTPases
    • DOI 10.1038/sj.onc.1210194, PII 1210194
    • Berenjeno IM, Nunez F, Bustelo XR. Transcriptomal profiling of the cellular transformation induced by Rho subfamily GTPases. Oncogene 2007;26:4295-4305 (Pubitemid 46975793)
    • (2007) Oncogene , vol.26 , Issue.29 , pp. 4295-4305
    • Berenjeno, I.M.1    Nunez, F.2    Bustelo, X.R.3
  • 27
    • 33744914879 scopus 로고    scopus 로고
    • Hypoxic regulation of vascular endothelial growth factor through the induction of phosphatidylinositol 3-kinase/Rho/ROCK and c-Myc
    • DOI 10.1074/jbc.M511763200
    • Mizukami Y, Fujiki K, Duerr EM, et al. Hypoxic regulation of vascular endothelial growth factor through the induction of phosphatidylinositol 3-kinase/Rho/ ROCK and c-Myc. J Biol Chem 2006;281:13957-13963 (Pubitemid 43848321)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.20 , pp. 13957-13963
    • Mizukami, Y.1    Fujiki, K.2    Duerr, E.-M.3    Gala, M.4    Jo, W.-S.5    Zhang, X.6    Chung, D.C.7
  • 28
    • 0042972556 scopus 로고    scopus 로고
    • Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis
    • Watnick RS, Cheng YN, Rangarajan A, et al. Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis. Cancer Cell 2003;3:219-231
    • (2003) Cancer Cell , vol.3 , pp. 219-231
    • Watnick, R.S.1    Cheng, Y.N.2    Rangarajan, A.3
  • 31
    • 2442564320 scopus 로고    scopus 로고
    • Correlation of amplification and overexpression of the c-myc oncogene in high-grade breast cancer: FISH, in situ hybridisation and immunohistochemical analyses
    • DOI 10.1038/sj.bjc.6601703
    • Blancato J, Singh B, Liu A, et al. Correlation of amplification and overexpression of the c-myc oncogene in high-grade breast cancer: FISH, in situ hybridisation and immunohistochemical analyses. Br J Cancer 2004; 90:1612-1619 (Pubitemid 38648247)
    • (2004) British Journal of Cancer , vol.90 , Issue.8 , pp. 1612-1619
    • Blancato, J.1    Singh, B.2    Liu, A.3    Liao, D.J.4    Dickson, R.B.5
  • 32
    • 33845923201 scopus 로고    scopus 로고
    • Overexpression of c-Myc and Bcl-2 during progression and distant metastasis of hormone-treated breast cancer
    • Planas-Silva MD, Bruggeman RD, Grenko RT, et al. Overexpression of c-Myc and Bcl-2 during progression and distant metastasis of hormone-treated breast cancer. Exp Mol Pathol 2007;82:85-90.
    • (2007) Exp Mol Pathol , vol.82 , pp. 85-90
    • Planas-Silva, M.D.1    Bruggeman, R.D.2    Grenko, R.T.3
  • 34
    • 0033790685 scopus 로고    scopus 로고
    • Dickson RB. c-Myc in breast cancer
    • Liao DJ, Dickson RB. c-Myc in breast cancer. Endocr Relat Cancer 2000;7:143-164
    • (2000) Endocr Relat Cancer , vol.7 , pp. 143-164
    • Liao, D.J.1
  • 35
    • 48949119505 scopus 로고    scopus 로고
    • The estrogen and c-Myc target gene HSPC111 is over-expressed in breast cancer and associated with poor patient outcome
    • Butt AJ, Sergio CM, Inman CK, et al. The estrogen and c-Myc target gene HSPC111 is over-expressed in breast cancer and associated with poor patient outcome. Breast Cancer Res 2008;10:R28.
    • (2008) Breast Cancer Res , vol.10
    • Butt, A.J.1    Sergio, C.M.2    Inman, C.K.3
  • 36
    • 58849148000 scopus 로고    scopus 로고
    • MicroRNA- 17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes
    • Inomata M, Tagawa H, Guo YM, et al. MicroRNA- 17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes. Blood 2009;113: 396-402.
    • (2009) Blood , vol.113 , pp. 396-402
    • Inomata, M.1    Tagawa, H.2    Guo, Y.M.3
  • 37
    • 58149328931 scopus 로고    scopus 로고
    • miR-17 and miR-20a temper an E2F1-induced G1 checkpoint to regulate cell cycle progression
    • Pickering MT, Stadler BM, Kowalik TF. miR-17 and miR-20a temper an E2F1-induced G1 checkpoint to regulate cell cycle progression. Oncogene 2009;28:140-145
    • (2009) Oncogene , vol.28 , pp. 140-145
    • Pickering, M.T.1    Stadler, B.M.2    Kowalik, T.F.3
  • 38
    • 0034695913 scopus 로고    scopus 로고
    • Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis
    • Hazan RB, Phillips GR, Qiao RF, et al. Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis. J Cell Biol 2000;148:779-790
    • (2000) J Cell Biol , vol.148 , pp. 779-790
    • Hazan, R.B.1    Phillips, G.R.2    Qiao, R.F.3
  • 39
    • 0032935495 scopus 로고    scopus 로고
    • An essential part for Rho-associated kinase in the transcellular invasion of tumor cells
    • DOI 10.1038/5587
    • Itoh K, Yoshioka K, Akedo H, et al. An essential part for Rho-associated kinase in the transcellular invasion of tumor cells. Nat Med 1999;5:221-225 (Pubitemid 29068531)
    • (1999) Nature Medicine , vol.5 , Issue.2 , pp. 221-225
    • Itoh, K.1    Yoshioka, K.2    Akedo, H.3    Uehata, M.4    Ishizaki, T.5    Narumiya, S.6
  • 40
    • 35948949806 scopus 로고    scopus 로고
    • Tissue-engineered bone serves as a target for metastasis of human breast cancer in a mouse model
    • DOI 10.1158/0008-5472.CAN-07-2483
    • Moreau JE, Anderson K, Mauney JR, et al. Tissueengineered bone serves as a target for metastasis of human breast cancer in a mouse model. Cancer Res 2007;67:10304-10308 (Pubitemid 350070804)
    • (2007) Cancer Research , vol.67 , Issue.21 , pp. 10304-10308
    • Moreau, J.E.1    Anderson, K.2    Mauney, J.R.3    Nguyen, T.4    Kaplan, D.L.5    Rosenblatt, M.6
  • 41
    • 34547735571 scopus 로고    scopus 로고
    • Synergistic action of the microRNA-17 polycistron and Myc in aggressive cancer development
    • DOI 10.1111/j.1349-7006.2007.00531.x
    • Tagawa H, Karube K, Tsuzuki S, et al. Synergistic action of the microRNA-17 polycistron and Myc in aggressive cancer development. Cancer Sci 2007;98:1482-1490 (Pubitemid 47241774)
    • (2007) Cancer Science , vol.98 , Issue.9 , pp. 1482-1490
    • Tagawa, H.1    Karube, K.2    Tsuzuki, S.3    Ohshima, K.4    Seto, M.5
  • 42
    • 37349100945 scopus 로고    scopus 로고
    • + myeloid cells that promote metastasis
    • + myeloid cells that promote metastasis. Cancer Cell 2008;13:23-35.
    • (2008) Cancer Cell , vol.13 , pp. 23-35
    • Yang, L.1    Huang, J.2    Ren, X.3
  • 43
    • 41749091574 scopus 로고    scopus 로고
    • Applications for ROCK kinase inhibition
    • Olson MF. Applications for ROCK kinase inhibition. Curr Opin Cell Biol 2008;20:242-248
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 242-248
    • Olson, M.F.1
  • 44
    • 62449294770 scopus 로고    scopus 로고
    • The actin cytoskeleton in cancer cell motility
    • Olson MF, Sahai E. The actin cytoskeleton in cancer cell motility. Clin Exp Metastasis 2009;26:273-287
    • (2009) Clin Exp Metastasis , vol.26 , pp. 273-287
    • Olson, M.F.1    Sahai, E.2
  • 45
    • 0034538306 scopus 로고    scopus 로고
    • C-myc amplification in breast cancer: A meta-analysis of its occurrence and prognostic relevance
    • Deming SL, Nass SJ, Dickson RB, et al. C-myc amplification in breast cancer: a meta-analysis of its occurrence and prognostic relevance. Br J Cancer 2000;83: 1688-1695
    • (2000) Br J Cancer , vol.83 , pp. 1688-1695
    • Deming, S.L.1    Nass, S.J.2    Dickson, R.B.3
  • 46
    • 0038024096 scopus 로고    scopus 로고
    • C-myc, not HER- 2/neu, can predict recurrence and mortality of patients with node-negative breast cancer
    • Schlotter CM, Vogt U, Bosse U, et al. C-myc, not HER- 2/neu, can predict recurrence and mortality of patients with node-negative breast cancer. Breast Cancer Res 2003;5:R30-6.
    • (2003) Breast Cancer Res , vol.5
    • Schlotter, C.M.1    Vogt, U.2    Bosse, U.3
  • 47
    • 0036483866 scopus 로고    scopus 로고
    • Protein expression and molecular analysis of c-myc gene in primary breast carcinomas using immunohistochemistry and differential polymerase chain reaction
    • Naidu R, Wahab NA, Yadav M, et al. Protein expression and molecular analysis of c-myc gene in primary breast carcinomas using immunohistochemistry and differential polymerase chain reaction. Int J Mol Med 2002;9:189-196
    • (2002) Int J Mol Med , vol.9 , pp. 189-196
    • Naidu, R.1    Wahab, N.A.2    Yadav, M.3
  • 48
    • 56749184298 scopus 로고    scopus 로고
    • Reflecting on 25 years with MYC
    • Meyer N, Penn LZ. Reflecting on 25 years with MYC. Nat Rev Cancer 2008;8:976-990
    • (2008) Nat Rev Cancer , vol.8 , pp. 976-990
    • Meyer, N.1    Penn, L.Z.2
  • 50
    • 0034017744 scopus 로고    scopus 로고
    • Pharmacological properties of Y-27632, a specific inhibitor of Rhoassociated kinases
    • Ishizaki T, Uehata M, Tamechika I, et al. Pharmacological properties of Y-27632, a specific inhibitor of Rhoassociated kinases. Mol Pharmacol 2000;57:976-983
    • (2000) Mol Pharmacol , vol.57 , pp. 976-983
    • Ishizaki, T.1    Uehata, M.2    Tamechika, I.3


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