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Volumn 22, Issue 2, 2010, Pages 345-355

Do Amyloid β-associated factors co-deposit with Aβ in mouse models for Alzheimer's disease?

Author keywords

Acute phase proteins; Alzheimer's disease; amyloid ; apolipoprotein E; complement; heparan sulfate proteoglycans; transgenic mice

Indexed keywords

AGRIN; ALPHA 2 MACROGLOBULIN; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E; CLASSICAL COMPLEMENT PATHWAY C3 C5 CONVERTASE; CLUSTERIN; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4; COMPLEMENT COMPONENT C5B; COMPLEMENT COMPONENT C7; COMPLEMENT COMPONENT C9; CYSTATIN C; GLYPICAN 1; HEPARAN SULFATE; INTERCELLULAR ADHESION MOLECULE 1; PERLECAN; SERUM AMYLOID P; SYNDECAN 3;

EID: 78650833299     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2010-100711     Document Type: Review
Times cited : (12)

References (118)
  • 1
    • 0021256895 scopus 로고
    • Alzheimer's disease: Initial report ofthe purification and characterization ofa novel cere-brovascular amyloid protein
    • Glenner GG, Wong CW (1984) Alzheimer's disease: initial report ofthe purification and characterization ofa novel cere-brovascular amyloid protein. Biochem Biophys Res Commun 120, 885-890.
    • (1984) Biochem Biophys Res Commun , vol.120 , pp. 885-890
    • Glenner, G.G.1    Wong, C.W.2
  • 3
    • 34548036227 scopus 로고    scopus 로고
    • Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
    • Ballatore C, Lee VM, Trojanowski JQ (2007) Tau-mediated neurodegeneration in Alzheimer's disease and related disorders. Nat Rev Neurosci 8, 663-672.
    • (2007) Nat Rev Neurosci , vol.8 , pp. 663-672
    • Ballatore, C.1    Lee, V.M.2    Trojanowski, J.Q.3
  • 6
    • 0033864011 scopus 로고    scopus 로고
    • Molecular genetics of Alzheimer's disease: The role of beta-amyloid and the presenilins
    • Tandon A, Rogaeva E, Mullan M, St George-Hyslop PH (2000) Molecular genetics of Alzheimer's disease: the role of beta-amyloid and the presenilins. Curr Opin Neurol 13, 377-384.
    • (2000) Curr Opin Neurol , vol.13 , pp. 377-384
    • Tandon, A.1    Rogaeva, E.2    Mullan, M.3    St George-Hyslop, P.H.4
  • 7
    • 0034534952 scopus 로고    scopus 로고
    • Identifying proteases that cleave A(PP)
    • Citron M (2000) Identifying proteases that cleave A(PP). Ann NY Acad Sci 920, 192-196.
    • (2000) Ann NY Acad Sci , vol.920 , pp. 192-196
    • Citron, M.1
  • 8
    • 0035927426 scopus 로고    scopus 로고
    • Secretase targets for Alzheimer's disease: Identification and therapeutic potential
    • Wolfe MS (2001) Secretase targets for Alzheimer's disease: identification and therapeutic potential. J Med Chem 44, 2039-2060.
    • (2001) J Med Chem , vol.44 , pp. 2039-2060
    • Wolfe, M.S.1
  • 9
    • 76849086405 scopus 로고    scopus 로고
    • The secretases: Enzymes with therapeutic potential in Alzheimer disease
    • De Strooper B., Vassar R, Golde T (2010) The secretases: enzymes with therapeutic potential in Alzheimer disease. Nat Rev Neurol 6, 99-107.
    • (2010) Nat Rev Neurol , vol.6 , pp. 99-107
    • De Strooper, B.1    Vassar, R.2    Golde, T.3
  • 10
    • 18844378852 scopus 로고    scopus 로고
    • Presenilin function and gamma-secretase activity
    • Brunkan AL, Goate AM (2005) Presenilin function and gamma-secretase activity. J Neurochem 93, 769-792.
    • (2005) J Neurochem , vol.93 , pp. 769-792
    • Brunkan, A.L.1    Goate, A.M.2
  • 13
    • 56349116391 scopus 로고    scopus 로고
    • Molecular genetics of Alzheimer's disease: An update
    • Brouwers N, Sleegers K, Van Broeckhoven C (2008) Molecular genetics of Alzheimer's disease: an update. Ann Med 40, 562-583.
    • (2008) Ann Med , vol.40 , pp. 562-583
    • Brouwers, N.1    Sleegers, K.2    Van Broeckhoven, C.3
  • 14
    • 0035937153 scopus 로고    scopus 로고
    • The Role of presenilins in gamma-secretase activity
    • Wolfe MS, Haass C (2001) The Role of presenilins in gamma-secretase activity. J Biol Chem 276, 5413-5416.
    • (2001) J Biol Chem , vol.276 , pp. 5413-5416
    • Wolfe, M.S.1    Haass, C.2
  • 16
    • 64549150594 scopus 로고    scopus 로고
    • Natural non-trasgenic animal models for research in Alzheimer's disease
    • Sarasa M, Pesini P (2009) Natural non-trasgenic animal models for research in Alzheimer's disease. Curr Alzheimer Res 6, 171-178.
    • (2009) Curr Alzheimer Res , vol.6 , pp. 171-178
    • Sarasa, M.1    Pesini, P.2
  • 18
    • 0028985574 scopus 로고
    • Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein
    • Blackwell C, Carr T, Clemens J, Donaldson T, Gillespie F, Guido T, Hagopian S, Johnson-Wood K, Khan K, Lee M, Lei-bowitz P, Lieberburg I, Little S, Masliah E, McConlogue L, Montoya-Zavala M, Mucke L, Paganini L, Penniman E, Power M, Schenk D, Seubert P, Snyder B, Soriano F, Tan H, Vitale J, Wadsworth S, Wolozin B, Zhao J
    • Games D, Adams D, Alessandrini R, Barbour R, Berthelette P, Blackwell C, Carr T, Clemens J, Donaldson T, Gillespie F, Guido T, Hagopian S, Johnson-Wood K, Khan K, Lee M, Lei-bowitz P, Lieberburg I, Little S, Masliah E, McConlogue L, Montoya-Zavala M, Mucke L, Paganini L, Penniman E, Power M, Schenk D, Seubert P, Snyder B, Soriano F, Tan H, Vitale J, Wadsworth S, Wolozin B, Zhao J (1995) Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein. Nature 373, 523-527.
    • (1995) Nature , vol.373 , pp. 523-527
    • Games, D.1    Adams, D.2    Alessandrini, R.3    Barbour, R.4    Berthelette, P.5
  • 19
    • 0033501744 scopus 로고    scopus 로고
    • Behavioral disturbances in transgenic mice overexpressing the V717F beta-amyloid precursor protein
    • Dodart JC, Meziane H, Mathis C, Bales KR, Paul SM, Ungerer A (1999) Behavioral disturbances in transgenic mice overexpressing the V717F beta-amyloid precursor protein. Behav Neurosci 113, 982-990.
    • (1999) Behav Neurosci , vol.113 , pp. 982-990
    • Dodart, J.C.1    Meziane, H.2    Mathis, C.3    Bales, K.R.4    Paul, S.M.5    Ungerer, A.6
  • 25
    • 2442594971 scopus 로고    scopus 로고
    • Early-onset and robust cerebral microvascular accumulation ofamyloid beta-protein in transgenic mice expressing low levels of a vas-culotropic Dutch/Iowa mutant form of amyloid beta-protein precursor
    • Davis J, Xu F, Deane R, Romanov G, Previti ML, Zeigler K, Zlokovic BV, Van Nostrand WE (2004) Early-onset and robust cerebral microvascular accumulation ofamyloid beta-protein in transgenic mice expressing low levels of a vas-culotropic Dutch/Iowa mutant form of amyloid beta-protein precursor. J Biol Chem 279, 20296-20306.
    • (2004) J Biol Chem , vol.279 , pp. 20296-20306
    • Davis, J.1    Xu, F.2    Deane, R.3    Romanov, G.4    Previti, M.L.5    Zeigler, K.6    Zlokovic, B.V.7    Van Nostrand, W.E.8
  • 28
    • 0035808361 scopus 로고    scopus 로고
    • Tau filament formation in transgenic mice expressing P301L tau
    • Gotz J, Chen F, Barmettler R, Nitsch RM (2001) Tau filament formation in transgenic mice expressing P301L tau. J Biol Chem 276, 529-534.
    • (2001) J Biol Chem , vol.276 , pp. 529-534
    • Gotz, J.1    Chen, F.2    Barmettler, R.3    Nitsch, R.M.4
  • 36
    • 36248968668 scopus 로고    scopus 로고
    • Heat shock proteins and amateur chaperones in amyloid-Beta accumulation and clearance in Alzheimer's disease
    • Wilhelmus MM, de Waal RM, Verbeek MM (2007) Heat shock proteins and amateur chaperones in amyloid-Beta accumulation and clearance in Alzheimer's disease. Mol Neu-robiol 35, 203-216.
    • (2007) Mol Neu-robiol , vol.35 , pp. 203-216
    • Wilhelmus, M.M.1    De Waal, R.M.2    Verbeek, M.M.3
  • 37
    • 0024364438 scopus 로고
    • The protease inhibitor, alpha 1-antichymotrypsin, is a component of the brain amyloid deposits in normal aging and Alzheimer's disease
    • Abraham CR, Potter H (1989) The protease inhibitor, alpha 1-antichymotrypsin, is a component of the brain amyloid deposits in normal aging and Alzheimer's disease. Ann Med 21,77-81.
    • (1989) Ann Med , vol.21 , pp. 77-81
    • Abraham, C.R.1    Potter, H.2
  • 38
    • 0028173205 scopus 로고
    • Amyloid-associated proteins alpha 1-antichymotrypsin and apolipoprotein e promote assembly of Alzheimer beta-protein into filaments
    • Ma J, Yee A, Brewer HB, Jr., Das S, Potter H (1994) Amyloid-associated proteins alpha 1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer beta-protein into filaments. Nature 372, 92-94.
    • (1994) Nature , vol.372 , pp. 92-94
    • Ma, J.1    Yee, A.2    Brewer, Jr.H.B.3    Das, S.4    Potter, H.5
  • 40
    • 0027970307 scopus 로고
    • Acceleration of Alzheimer's fibril formation by apolipoprotein e in vitro
    • Wisniewski T, Castano EM, Golabek A, Vogel T, Frangione B (1994) Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro. Am J Pathol 145, 1030-1035.
    • (1994) Am J Pathol , vol.145 , pp. 1030-1035
    • Wisniewski, T.1    Castano, E.M.2    Golabek, A.3    Vogel, T.4    Frangione, B.5
  • 41
    • 0024273721 scopus 로고
    • The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy in Alzheimer's disease
    • Snow AD, Mar H, Nochlin D, Kimata K, Kato M, Suzuki S, Hassell J, Wight TN (1988) The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy in Alzheimer's disease. Am J Pathol 133, 456-463.
    • (1988) Am J Pathol , vol.133 , pp. 456-463
    • Snow, A.D.1    Mar, H.2    Nochlin, D.3    Kimata, K.4    Kato, M.5    Suzuki, S.6    Hassell, J.7    Wight, T.N.8
  • 43
    • 0033953066 scopus 로고    scopus 로고
    • Agrin binds to beta-amyloid (Abeta), accelerates abeta fibril formation, and is localized to Abeta deposits in Alzheimer's disease brain
    • Cotman SL, Halfter W, Cole GJ (2000) Agrin binds to beta-amyloid (Abeta), accelerates abeta fibril formation, and is localized to Abeta deposits in Alzheimer's disease brain. Mol CellNeurosci 15, 183-198.
    • (2000) Mol CellNeurosci , vol.15 , pp. 183-198
    • Cotman, S.L.1    Halfter, W.2    Cole, G.J.3
  • 45
    • 0029047722 scopus 로고
    • Differential binding of vascular cell-derived proteoglycans (perlecan, biglycan, decorin, and versican) to the beta-amyloid protein of Alzheimer's disease
    • Snow AD, Kinsella MG, Parks E, Sekiguchi RT, Miller JD, Kimata K, Wight TN (1995) Differential binding of vascular cell-derived proteoglycans (perlecan, biglycan, decorin, and versican) to the beta-amyloid protein of Alzheimer's disease. Arch Biochem Biophys 320, 84-95.
    • (1995) Arch Biochem Biophys , vol.320 , pp. 84-95
    • Snow, A.D.1    Kinsella, M.G.2    Parks, E.3    Sekiguchi, R.T.4    Miller, J.D.5    Kimata, K.6    Wight, T.N.7
  • 46
    • 0030725311 scopus 로고    scopus 로고
    • Perlecan binds to the beta-amyloid proteins (A beta) of Alzheimer's disease, accelerates A beta fibril formation, and maintains A beta fibril stability
    • Castillo GM, Ngo C, Cummings J, Wight TN, Snow AD (1997) Perlecan binds to the beta-amyloid proteins (A beta) of Alzheimer's disease, accelerates A beta fibril formation, and maintains A beta fibril stability. J Neurochem 69, 24522465.
    • (1997) J Neurochem , vol.69 , pp. 24522465
    • Castillo, G.M.1    Ngo, C.2    Cummings, J.3    Wight, T.N.4    Snow, A.D.5
  • 47
    • 0033026552 scopus 로고    scopus 로고
    • The sulfate moieties of glycosaminoglycans are critical for the enhancement of beta-amyloid protein fibril formation
    • Castillo GM, Lukito W, Wight TN, Snow AD (1999) The sulfate moieties of glycosaminoglycans are critical for the enhancement of beta-amyloid protein fibril formation. J Neurochem 72, 1681-1687.
    • (1999) J Neurochem , vol.72 , pp. 1681-1687
    • Castillo, G.M.1    Lukito, W.2    Wight, T.N.3    Snow, A.D.4
  • 48
    • 0033943119 scopus 로고    scopus 로고
    • Transgenic mouse models of Alzheimer's disease
    • Bornemann KD, Staufenbiel M (2000) Transgenic mouse models of Alzheimer's disease. Ann N Y Acad Sci 908, 260266.
    • (2000) Ann N y Acad Sci , vol.908 , pp. 260266
    • Bornemann, K.D.1    Staufenbiel, M.2
  • 50
    • 77956512204 scopus 로고    scopus 로고
    • Limited expression of hep-aran sulfate proteoglycans associated with Abeta deposits in the AftPPswe/PS 1dE9 mouse model for Alzheimer's disease
    • Timmer NM, Herbert MK, Kleinovink JW, Kiliaan AJ, de Waal RM, Verbeek MM (2010) Limited expression of hep-aran sulfate proteoglycans associated with Abeta deposits in the AftPPswe/PS 1dE9 mouse model for Alzheimer's disease. Neuropathol Appl Neurobiol 36, 478-486.
    • (2010) Neuropathol Appl Neurobiol , vol.36 , pp. 478-486
    • Timmer, N.M.1    Herbert, M.K.2    Kleinovink, J.W.3    Kiliaan, A.J.4    De Waal, R.M.5    Verbeek, M.M.6
  • 51
    • 67649805281 scopus 로고    scopus 로고
    • Amyloid precursor protein transgenic mouse models and Alzheimer's disease: Understanding the paradigms, limitations, and contributions
    • Kokjohn TA, Roher AE (2009) Amyloid precursor protein transgenic mouse models and Alzheimer's disease: understanding the paradigms, limitations, and contributions. Alzheimers Dement 5, 340-347.
    • (2009) Alzheimers Dement , vol.5 , pp. 340-347
    • Kokjohn, T.A.1    Roher, A.E.2
  • 52
    • 0024387388 scopus 로고
    • Proteoglycans in the pathogenesis of Alzheimer's disease and other amyloidoses
    • Snow AD, Wight TN (1989) Proteoglycans in the pathogenesis of Alzheimer's disease and other amyloidoses. Neurobiol Aging 10, 481-497.
    • (1989) Neurobiol Aging , vol.10 , pp. 481-497
    • Snow, A.D.1    Wight, T.N.2
  • 53
    • 0022350033 scopus 로고
    • Apolipoprotein e associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system
    • Boyles JK, Pitas RE, Wilson E, Mahley RW, Taylor JM (1985) Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system. J Clin Invest 76, 1501-1513.
    • (1985) J Clin Invest , vol.76 , pp. 1501-1513
    • Boyles, J.K.1    Pitas, R.E.2    Wilson, E.3    Mahley, R.W.4    Taylor, J.M.5
  • 54
    • 75549089646 scopus 로고    scopus 로고
    • Apolipoprotein e protects cultured pericytes and astrocytes from D-Abeta(1-40)-mediated cell death
    • Bruinsma IB, Wilhelmus MM, Kox M, Veerhuis R, de Waal RM, Verbeek MM (2010) Apolipoprotein E protects cultured pericytes and astrocytes from D-Abeta(1-40)-mediated cell death. Brain Res 1315, 169-180.
    • (2010) Brain Res , vol.1315 , pp. 169-180
    • Bruinsma, I.B.1    Wilhelmus, M.M.2    Kox, M.3    Veerhuis, R.4    De Waal, R.M.5    Verbeek, M.M.6
  • 56
    • 0023280054 scopus 로고
    • Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain
    • Pitas RE, Boyles JK, Lee SH, Hui D, Weisgraber KH (1987) Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain. JBiol Chem 262, 14352-14360.
    • (1987) JBiol Chem , vol.262 , pp. 14352-14360
    • Pitas, R.E.1    Boyles, J.K.2    Lee, S.H.3    Hui, D.4    Weisgraber, K.H.5
  • 58
    • 68249134074 scopus 로고    scopus 로고
    • The role of apolipoprotein e in Alzheimer's disease
    • Kim J, Basak JM, Holtzman DM (2009) The role of apolipoprotein E in Alzheimer's disease. Neuron 63, 287-303.
    • (2009) Neuron , vol.63 , pp. 287-303
    • Kim, J.1    Basak, J.M.2    Holtzman, D.M.3
  • 59
    • 0025971426 scopus 로고
    • Apolipoprotein e immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease
    • Namba Y, Tomonaga M, Kawasaki H, Otomo E, Ikeda K (1991) Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease. Brain Res 541, 163-166.
    • (1991) Brain Res , vol.541 , pp. 163-166
    • Namba, Y.1    Tomonaga, M.2    Kawasaki, H.3    Otomo, E.4    Ikeda, K.5
  • 60
    • 0842342533 scopus 로고    scopus 로고
    • Immunohistochemical study of distribution of apolipoproteins e and D in human cerebral beta amyloid deposits
    • Navarro A, Del VE, Astudillo A, Gonzalez del RC, Tolivia J (2003) Immunohistochemical study of distribution of apolipoproteins E and D in human cerebral beta amyloid deposits. Exp Neurol 184, 697-704.
    • (2003) Exp Neurol , vol.184 , pp. 697-704
    • Navarro, A.1    Del, V.E.2    Astudillo, A.3    Gonzalez Del, R.C.4    Tolivia, J.5
  • 61
    • 0026542786 scopus 로고
    • Apolipoprotein E: Apatho-logical chaperone protein in patients with cerebral and systemic amyloid
    • Wisniewski T, Frangione B (1992) Apolipoprotein E: apatho-logical chaperone protein in patients with cerebral and systemic amyloid. Neurosci Lett 135, 235-238.
    • (1992) Neurosci Lett , vol.135 , pp. 235-238
    • Wisniewski, T.1    Frangione, B.2
  • 62
    • 0029757510 scopus 로고    scopus 로고
    • Apolipoprotein e distribution among different plaque types in Alzheimer's disease: Implications for its role in plaque progression
    • Sheng JG, Mrak RE, Griffin WS (1996) Apolipoprotein E distribution among different plaque types in Alzheimer's disease: implications for its role in plaque progression. Neu-ropathol Appl Neurobiol 22, 334-341.
    • (1996) Neu-ropathol Appl Neurobiol , vol.22 , pp. 334-341
    • Sheng, J.G.1    Mrak, R.E.2    Griffin, W.S.3
  • 63
    • 0034183020 scopus 로고    scopus 로고
    • Elevated A beta and apolipoprotein e in A betaPP transgenic mice and its relationship to amyloid accumulation in Alzheimer's disease
    • Kuo YM, Crawford F, Mullan M, Kokjohn TA, Emmer-ling MR, Weller RO, Roher AE (2000) Elevated A beta and apolipoprotein E in A betaPP transgenic mice and its relationship to amyloid accumulation in Alzheimer's disease. MolMed 6, 430-439.
    • (2000) MolMed , vol.6 , pp. 430-439
    • Kuo, Y.M.1    Crawford, F.2    Mullan, M.3    Kokjohn, T.A.4    Emmerling, M.R.5    Weller, R.O.6    Roher, A.E.7
  • 64
    • 0035805091 scopus 로고    scopus 로고
    • Apolipoprotein e deposition and astroglio-sis are associated with maturation ofbeta-amyloid plaques in betaAftPPswe transgenic mouse: Implications for the patho-genesis of Alzheimer's disease
    • Terai K, Iwai A, Kawabata S, Sasamata M, Miyata K, Yamaguchi T (2001) Apolipoprotein E deposition and astroglio-sis are associated with maturation ofbeta-amyloid plaques in betaAftPPswe transgenic mouse: Implications for the patho-genesis of Alzheimer's disease. Brain Res 900, 48-56.
    • (2001) Brain Res , vol.900 , pp. 48-56
    • Terai, K.1    Iwai, A.2    Kawabata, S.3    Sasamata, M.4    Miyata, K.5    Yamaguchi, T.6
  • 65
    • 2942611429 scopus 로고    scopus 로고
    • Transgenic mice overexpressing amyloid beta protein are an incomplete model of Alzheimer disease
    • Schwab C, Hosokawa M, McGeer PL (2004) Transgenic mice overexpressing amyloid beta protein are an incomplete model of Alzheimer disease. Exp Neurol 188, 52-64.
    • (2004) Exp Neurol , vol.188 , pp. 52-64
    • Schwab, C.1    Hosokawa, M.2    McGeer, P.L.3
  • 67
    • 0035664046 scopus 로고    scopus 로고
    • Neuropathological characterization of mutant amyloid precursor protein yeast artificial chromosome transgenic mice
    • Kulnane LS, Lamb BT (2001) Neuropathological characterization of mutant amyloid precursor protein yeast artificial chromosome transgenic mice. Neurobiol Dis 8, 982-992.
    • (2001) Neurobiol Dis , vol.8 , pp. 982-992
    • Kulnane, L.S.1    Lamb, B.T.2
  • 68
    • 0030007964 scopus 로고    scopus 로고
    • Sequence of deposition ofheteroge-neous amyloid beta-peptides and APO e in Down syndrome: Implications for initial events in amyloid plaque formation
    • Lemere CA, Blusztajn JK, Yamaguchi H, Wisniewski T, Sai-do TC, Selkoe DJ(1996) Sequence of deposition ofheteroge-neous amyloid beta-peptides and APO E in Down syndrome: implications for initial events in amyloid plaque formation. NeurobiolDis 3, 16-32.
    • (1996) NeurobiolDis , vol.3 , pp. 16-32
    • Lemere, C.A.1    Blusztajn, J.K.2    Yamaguchi, H.3    Wisniewski, T.4    Sai-Do, T.C.5    Selkoe, D.J.6
  • 74
    • 0030014990 scopus 로고    scopus 로고
    • Apolipoprotein J and Alzheimer's amyloid beta solubility
    • Matsubara E, Soto C, Governale S, Frangione B, Ghiso J (1996) Apolipoprotein J and Alzheimer's amyloid beta solubility. Biochem J 316 (Pt 2), 671-679.
    • (1996) Biochem J , vol.316 , Issue.PART 2 , pp. 671-679
    • Matsubara, E.1    Soto, C.2    Governale, S.3    Frangione, B.4    Ghiso, J.5
  • 76
    • 0030271257 scopus 로고    scopus 로고
    • Expression of complement in the brain: Role in health and disease
    • Morgan BP, Gasque P (1996) Expression of complement in the brain: role in health and disease. Immunol Today 17, 461-466.
    • (1996) Immunol Today , vol.17 , pp. 461-466
    • Morgan, B.P.1    Gasque, P.2
  • 77
    • 0032479929 scopus 로고    scopus 로고
    • Complement-dependent proinflammatory properties of the Alzheimer's disease beta-peptide
    • Bradt BM, Kolb WP, Cooper NR (1998) Complement-dependent proinflammatory properties of the Alzheimer's disease beta-peptide. J Exp Med 188, 431-438.
    • (1998) J Exp Med , vol.188 , pp. 431-438
    • Bradt, B.M.1    Kolb, W.P.2    Cooper, N.R.3
  • 78
    • 0028178458 scopus 로고
    • Beta-Amyloid activates complement by binding to a specific region of the collagen-like domain of the C1q A chain
    • Jiang H, Burdick D, Glabe CG, Cotman CW, Tenner AJ (1994) beta-Amyloid activates complement by binding to a specific region of the collagen-like domain of the C1q A chain. J Immunol 152, 5050-5059.
    • (1994) J Immunol , vol.152 , pp. 5050-5059
    • Jiang, H.1    Burdick, D.2    Glabe, C.G.3    Cotman, C.W.4    Tenner, A.J.5
  • 79
    • 0033061855 scopus 로고    scopus 로고
    • Up-regulated production and activation of the complement system in Alzheimer's disease brain
    • Yasojima K, Schwab C, McGeer EG, McGeer PL (1999) Up-regulated production and activation of the complement system in Alzheimer's disease brain. Am J Pathol 154, 927936.
    • (1999) Am J Pathol , vol.154 , pp. 927936
    • Yasojima, K.1    Schwab, C.2    McGeer, E.G.3    McGeer, P.L.4
  • 81
    • 18144373149 scopus 로고    scopus 로고
    • Using animal models to determine the significance of complement activation in Alzheimer's disease
    • Loeffler DA (2004) Using animal models to determine the significance of complement activation in Alzheimer's disease. J Neuroinflammation 1, 18.
    • (2004) J Neuroinflammation , vol.1 , pp. 18
    • Loeffler, D.A.1
  • 82
    • 0028135459 scopus 로고
    • Enhanced aggregation and beta structure of amyloid beta peptide after coincubation with C1q
    • Webster S, O'Barr S, Rogers J (1994) Enhanced aggregation and beta structure of amyloid beta peptide after coincubation with C1q. J Neurosci Res 39, 448-456.
    • (1994) J Neurosci Res , vol.39 , pp. 448-456
    • Webster, S.1    O'Barr, S.2    Rogers, J.3
  • 83
    • 0028836519 scopus 로고
    • Complement-mediated neurotoxicity is regulated by homologous restriction
    • Shen Y, Halperin JA, Lee CM (1995) Complement-mediated neurotoxicity is regulated by homologous restriction. Brain Res 671, 282-292.
    • (1995) Brain Res , vol.671 , pp. 282-292
    • Shen, Y.1    Halperin, J.A.2    Lee, C.M.3
  • 85
    • 3242766671 scopus 로고    scopus 로고
    • Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease
    • Fonseca MI, Zhou J, Botto M, Tenner AJ (2004) Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease. J Neurosci 24, 6457-6465.
    • (2004) J Neurosci , vol.24 , pp. 6457-6465
    • Fonseca, M.I.1    Zhou, J.2    Botto, M.3    Tenner, A.J.4
  • 86
    • 49549095792 scopus 로고    scopus 로고
    • Complement C3 and C4 expression in C1q sufficient and deficient mouse models of Alzheimer's disease
    • Zhou J, Fonseca MI, Pisalyaput K, Tenner AJ (2008) Complement C3 and C4 expression in C1q sufficient and deficient mouse models of Alzheimer's disease. J Neurochem 106, 2080-2092.
    • (2008) J Neurochem , vol.106 , pp. 2080-2092
    • Zhou, J.1    Fonseca, M.I.2    Pisalyaput, K.3    Tenner, A.J.4
  • 88
    • 36849063880 scopus 로고    scopus 로고
    • Induction of complement proteins in a mouse model for cerebral mi-crovascular A beta deposition
    • Fan R, DeFilippis K, Van Nostrand WE (2007) Induction of complement proteins in a mouse model for cerebral mi-crovascular A beta deposition. J Neuroinflammation 4, 22.
    • (2007) J Neuroinflammation , vol.4 , pp. 22
    • Fan, R.1    Defilippis, K.2    Van Nostrand, W.E.3
  • 89
    • 71049194870 scopus 로고    scopus 로고
    • Expression of complement system components during aging and amyloid deposition in AftPP transgenic mice
    • Reichwald J, Danner S, Wiederhold KH, Staufenbiel M (2009) Expression of complement system components during aging and amyloid deposition in AftPP transgenic mice. J Neuroinflammation 6, 35.
    • (2009) J Neuroinflammation , vol.6 , pp. 35
    • Reichwald, J.1    Danner, S.2    Wiederhold, K.H.3    Staufenbiel, M.4
  • 90
    • 0033133360 scopus 로고    scopus 로고
    • The mouse C1q A-chain sequence alters beta-amyloid-induced complement activation
    • Webster SD, Tenner AJ, Poulos TL, Cribbs DH (1999) The mouse C1q A-chain sequence alters beta-amyloid-induced complement activation. Neurobiol Aging 20, 297-304.
    • (1999) Neurobiol Aging , vol.20 , pp. 297-304
    • Webster, S.D.1    Tenner, A.J.2    Poulos, T.L.3    Cribbs, D.H.4
  • 91
    • 0029971956 scopus 로고    scopus 로고
    • Mouse complement component C4 is devoid ofclassical pathway C5 convertase subunit activity
    • Ebanks RO, Isenman DE (1996) Mouse complement component C4 is devoid ofclassical pathway C5 convertase subunit activity. Mol Immunol 33, 297-309.
    • (1996) Mol Immunol , vol.33 , pp. 297-309
    • Ebanks, R.O.1    Isenman, D.E.2
  • 94
    • 0023838532 scopus 로고
    • Immunochem-ical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease
    • Abraham CR, Selkoe DJ, Potter H (1988) Immunochem-ical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease. Cell 52, 487-501.
    • (1988) Cell , vol.52 , pp. 487-501
    • Abraham, C.R.1    Selkoe, D.J.2    Potter, H.3
  • 95
    • 0025309009 scopus 로고
    • Serum amyloid P immunore-activity in hippocampal tangles, plaques and vessels: Implications for leakage across the blood-brain barrier in Alzheimer's disease
    • Kalaria RN, Grahovac I (1990) Serum amyloid P immunore-activity in hippocampal tangles, plaques and vessels: implications for leakage across the blood-brain barrier in Alzheimer's disease. Brain Res 516, 349-353.
    • (1990) Brain Res , vol.516 , pp. 349-353
    • Kalaria, R.N.1    Grahovac, I.2
  • 96
    • 0035696284 scopus 로고    scopus 로고
    • The pentraxins: Possible role in Alzheimer's disease and other innate inflammatory diseases
    • McGeer EG, Yasojima K, Schwab C, McGeer PL (2001) The pentraxins: possible role in Alzheimer's disease and other innate inflammatory diseases. Neurobiol Aging 22, 843-848.
    • (2001) Neurobiol Aging , vol.22 , pp. 843-848
    • McGeer, E.G.1    Yasojima, K.2    Schwab, C.3    McGeer, P.L.4
  • 97
    • 0027394985 scopus 로고
    • Human serum amyloid P component oligomers bind and activate the classical complement pathway via residues 14-26 and 76-92 of the A chain collagen-like region of C1q
    • Ying SC, Gewurz AT, Jiang H, Gewurz H (1993) Human serum amyloid P component oligomers bind and activate the classical complement pathway via residues 14-26 and 76-92 of the A chain collagen-like region of C1q. J Immunol 150, 169-176.
    • (1993) J Immunol , vol.150 , pp. 169-176
    • Ying, S.C.1    Gewurz, A.T.2    Jiang, H.3    Gewurz, H.4
  • 98
    • 0032732637 scopus 로고    scopus 로고
    • Serum amyloid P is not present in amyloid beta deposits ofa transgenic animal model
    • Shi J, Perry G, Aliev G, Smith MA, Ashe KH, Friedland RP (1999) Serum amyloid P is not present in amyloid beta deposits ofa transgenic animal model. Neuroreport 10, 32293232.
    • (1999) Neuroreport , vol.10 , pp. 3229-3232
    • Shi, J.1    Perry, G.2    Aliev, G.3    Smith, M.A.4    Ashe, K.H.5    Friedland, R.P.6
  • 99
    • 0036330242 scopus 로고    scopus 로고
    • Labeling ofcerebralamyloid beta deposits in vivo using intranasal basic fibroblast growth factor and serum amyloid P component in mice
    • Shi J, Perry G, Berridge MS, Aliev G, Siedlak SL, Smith MA, LaManna JC, Friedland RP (2002) Labeling ofcerebralamyloid beta deposits in vivo using intranasal basic fibroblast growth factor and serum amyloid P component in mice. J Nucl Med 43, 1044-1051.
    • (2002) J Nucl Med , vol.43 , pp. 1044-1051
    • Shi, J.1    Perry, G.2    Berridge, M.S.3    Aliev, G.4    Siedlak, S.L.5    Smith, M.A.6    Lamanna, J.C.7    Friedland, R.P.8
  • 101
    • 0027160249 scopus 로고
    • Alpha 2-Macroglobulin expression in neuritic-type plaques in patients with Alzheimer's disease
    • Van Gool D., De Strooper B., Van Leuven F., Triau E, Dom R (1993) alpha 2-Macroglobulin expression in neuritic-type plaques in patients with Alzheimer's disease. Neurobiol Aging 14, 233-237.
    • (1993) Neurobiol Aging , vol.14 , pp. 233-237
    • Van Gool, D.1    De Strooper, B.2    Van Leuven, F.3    Triau, E.4    Dom, R.5
  • 103
    • 0041939975 scopus 로고    scopus 로고
    • Deposition of Alpha2-Macroglobulin in Fibrillar Type of Senile Plaques in the Brain of PS/A(PP-Transgenic Mice
    • Kondo T, Tooyama I (2003) Deposition of Alpha2-Macroglobulin in Fibrillar Type of Senile Plaques in the Brain of PS/A(PP-Transgenic Mice. ActaHistochem Cytochem 36, 215-220.
    • (2003) ActaHistochem Cytochem , vol.36 , pp. 215-220
    • Kondo, T.1    Tooyama, I.2
  • 104
    • 0028986858 scopus 로고
    • Alpha 1-antichymotrypsin regulates Alzheimer beta-amyloid peptide fibril formation
    • Eriksson S, Janciauskiene S, Lannfelt L (1995) Alpha 1-antichymotrypsin regulates Alzheimer beta-amyloid peptide fibril formation. Proc Natl Acad Sci USA 92, 2313-2317.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 2313-2317
    • Eriksson, S.1    Janciauskiene, S.2    Lannfelt, L.3
  • 105
    • 0032561313 scopus 로고    scopus 로고
    • Alzheimer's peptide Abeta1-42 binds to two beta-sheets of alpha1-antichymotrypsin and transforms it from inhibitor to substrate
    • Janciauskiene S, Rubin H, Lukacs CM, Wright HT (1998) Alzheimer's peptide Abeta1-42 binds to two beta-sheets of alpha1-antichymotrypsin and transforms it from inhibitor to substrate. J Biol Chem 273, 28360-28364.
    • (1998) J Biol Chem , vol.273 , pp. 28360-28364
    • Janciauskiene, S.1    Rubin, H.2    Lukacs, C.M.3    Wright, H.T.4
  • 106
    • 0035282790 scopus 로고    scopus 로고
    • Alpha-1-antichymotrypsin promotes beta-sheet amyloid plaque deposition in a transgenic mouse model of Alzheimer's disease
    • Nilsson LN, Bales KR, DiCarlo G, Gordon MN, Morgan D, Paul SM, Potter H (2001) Alpha-1-antichymotrypsin promotes beta-sheet amyloid plaque deposition in a transgenic mouse model of Alzheimer's disease. J Neurosci 21, 14441451.
    • (2001) J Neurosci , vol.21 , pp. 1444-1451
    • Nilsson, L.N.1    Bales, K.R.2    Dicarlo, G.3    Gordon, M.N.4    Morgan, D.5    Paul, S.M.6    Potter, H.7
  • 107
    • 0028239387 scopus 로고
    • Accumulation of intercellular adhesion molecule-1 in senile plaques in brain tissue of patients with Alzheimer's disease
    • Verbeek MM, Otte-Holler I, Westphal JR, Wesseling P, Ruiter DJ, de Waal RM (1994) Accumulation of intercellular adhesion molecule-1 in senile plaques in brain tissue of patients with Alzheimer's disease. Am J Pathol 144, 104-116.
    • (1994) Am J Pathol , vol.144 , pp. 104-116
    • Verbeek, M.M.1    Otte-Holler, I.2    Westphal, J.R.3    Wesseling, P.4    Ruiter, D.J.5    De Waal, R.M.6
  • 108
    • 15844373497 scopus 로고    scopus 로고
    • Differential expression of intercellular adhesion molecule-1 (ICAM-1) in the A beta-containing lesions in brains of patients with dementia of the Alzheimer type
    • Verbeek MM, Otte-Holler I, Wesseling P, Ruiter DJ, de Waal RM (1996) Differential expression of intercellular adhesion molecule-1 (ICAM-1) in the A beta-containing lesions in brains of patients with dementia of the Alzheimer type. Acta Neuropathol 91, 608-615.
    • (1996) Acta Neuropathol , vol.91 , pp. 608-615
    • Verbeek, M.M.1    Otte-Holler, I.2    Wesseling, P.3    Ruiter, D.J.4    De Waal, R.M.5
  • 109
    • 0037162769 scopus 로고    scopus 로고
    • Beta-amyloid-associated expression of intercellular adhesion molecule-1 in brain cortical tissue of transgenic Tg2576 mice
    • Apelt J, Lessig J, Schliebs R (2002) Beta-amyloid-associated expression of intercellular adhesion molecule-1 in brain cortical tissue of transgenic Tg2576 mice. Neurosci Lett 329, 111-115.
    • (2002) Neurosci Lett , vol.329 , pp. 111-115
    • Apelt, J.1    Lessig, J.2    Schliebs, R.3
  • 111
    • 0029999658 scopus 로고    scopus 로고
    • The molecular pathology of hereditary cystatin C amyloid angiopathy causing brain hemorrhage
    • Olafsson I, Thorsteinsson L, Jensson O (1996) The molecular pathology of hereditary cystatin C amyloid angiopathy causing brain hemorrhage. Brain Pathol 6, 121-126.
    • (1996) Brain Pathol , vol.6 , pp. 121-126
    • Olafsson, I.1    Thorsteinsson, L.2    Jensson, O.3
  • 114
    • 53849106834 scopus 로고    scopus 로고
    • Cystatin C-cathepsin B axis regulates amyloid beta levels and associated neuronal deficits in an animal model of Alzheimer's disease
    • Sun B, Zhou Y, Halabisky B, Lo I, Cho SH, Mueller-Steiner S, Devidze N, Wang X, Grubb A, Gan L (2008) Cystatin C-cathepsin B axis regulates amyloid beta levels and associated neuronal deficits in an animal model of Alzheimer's disease. Neuron 60, 247-257.
    • (2008) Neuron , vol.60 , pp. 247-257
    • Sun, B.1    Zhou, Y.2    Halabisky, B.3    Lo, I.4    Cho, S.H.5    Mueller-Steiner, S.6    Devidze, N.7    Wang, X.8    Grubb, A.9    Gan, L.10
  • 116
    • 3042643601 scopus 로고    scopus 로고
    • Mostly separate distributions of CLAC-versus A(rfsti 40-or Thioflavin S-reactivities in senile plaques reveal two distinct subpopu-lations of (-amyloid deposits
    • Kowa H, Sakakura T, Matsuura Y, Wakabayashi T, Mann DM, Duff K, Tsuji S, Hashimoto T, Iwatsubo T (2004) Mostly separate distributions of CLAC-versus A(40-or Thioflavin S-reactivities in senile plaques reveal two distinct subpopu-lations of (-amyloid deposits. Am J Pathol 165, 273-281.
    • (2004) Am J Pathol , vol.165 , pp. 273-281
    • Kowa, H.1    Sakakura, T.2    Matsuura, Y.3    Wakabayashi, T.4    Mann, D.M.5    Duff, K.6    Tsuji, S.7    Hashimoto, T.8    Iwatsubo, T.9


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