Early-onset and Robust Cerebral Microvascular Accumulation of Amyloid β-Protein in Transgenic Mice Expressing Low Levels of a Vasculotropic Dutch/Iowa Mutant Form of Amyloid β-Protein Precursor

Journal of Biological Chemistry

Volumn 279, Issue 19, 2004, Pages 20296-20306

  Davis, Judianne ^a   Xu, Feng ^a   Deane, Rashid ^b   Romanov, Galina ^a   Previti, Mary Lou ^a   Zeigler, Kelly ^a   Zlokovic, Berislav V ^b   Van Nostrand, William E ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; BRAIN; IMMUNOLOGY; PATHOLOGY; PROTEINS;

MICROVESSELS; MUTATIONS; PRECURSORS;

BIOCHEMISTRY;

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; DIRECT YELLOW 7; THIOFLAVINE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; BLEEDING; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE OVEREXPRESSION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MUTATION; NONHUMAN; ONSET AGE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN TRANSPORT; SENILE PLAQUE; TRANSGENIC MOUSE;

AMYLOID BETA-PROTEIN; ANIMALS; BRAIN; DNA, COMPLEMENTARY; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENETIC VECTORS; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROCIRCULATION; MODELS, GENETIC; MUTATION; PEPTIDES; PROMOTER REGIONS (GENETICS); THIAZOLES; TIME FACTORS; TISSUE DISTRIBUTION; TRANSGENES;

ANIMALIA; MUS MUSCULUS;

EID: 2442594971     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M312946200     Document Type: Article

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