-
1
-
-
0032694577
-
'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
-
Nicholson J.K., Lindon J.C., Holmes E. 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 1999, 29:1181-1189.
-
(1999)
Xenobiotica
, vol.29
, pp. 1181-1189
-
-
Nicholson, J.K.1
Lindon, J.C.2
Holmes, E.3
-
2
-
-
0036007687
-
Metabolomics - the link between genotypes and phenotypes
-
Fiehn O. Metabolomics - the link between genotypes and phenotypes. Plant Molecular Biology 2002, 48:155-171.
-
(2002)
Plant Molecular Biology
, vol.48
, pp. 155-171
-
-
Fiehn, O.1
-
3
-
-
16244402990
-
Metabolomics: current analytical platforms and methodologies
-
Dunn W.B., Ellis D.I. Metabolomics: current analytical platforms and methodologies. Trac-Trends in Analytical Chemistry 2005, 24:285-294.
-
(2005)
Trac-Trends in Analytical Chemistry
, vol.24
, pp. 285-294
-
-
Dunn, W.B.1
Ellis, D.I.2
-
4
-
-
20544466649
-
Metabonomics in toxicology: a review
-
Robertson D.G. Metabonomics in toxicology: a review. Toxicological Sciences 2005, 85:809-822.
-
(2005)
Toxicological Sciences
, vol.85
, pp. 809-822
-
-
Robertson, D.G.1
-
5
-
-
0034130232
-
Chemometric models for toxicity classification based on NMR spectra of biofluids
-
Holmes E., Nicholls A.W., Lindon J.C., et al. Chemometric models for toxicity classification based on NMR spectra of biofluids. Chemical Research in Toxicology 2000, 13:471-478.
-
(2000)
Chemical Research in Toxicology
, vol.13
, pp. 471-478
-
-
Holmes, E.1
Nicholls, A.W.2
Lindon, J.C.3
-
6
-
-
9944247186
-
Using chemometrics for navigating in the large data sets of genomics, proteomics, and metabonomics (gpm)
-
Eriksson L., Antti H., Gottfries J., et al. Using chemometrics for navigating in the large data sets of genomics, proteomics, and metabonomics (gpm). Analytical and Bioanalytical Chemistry 2004, 380:419-429.
-
(2004)
Analytical and Bioanalytical Chemistry
, vol.380
, pp. 419-429
-
-
Eriksson, L.1
Antti, H.2
Gottfries, J.3
-
7
-
-
1942470073
-
Metabolomics by numbers: acquiring and understanding global metabolite data
-
Goodacre R., Vaidyanathan S., Dunn W.B., Harrigan G.G., Kell D.B. Metabolomics by numbers: acquiring and understanding global metabolite data. Trends in Biotechnology 2004, 22:245-252.
-
(2004)
Trends in Biotechnology
, vol.22
, pp. 245-252
-
-
Goodacre, R.1
Vaidyanathan, S.2
Dunn, W.B.3
Harrigan, G.G.4
Kell, D.B.5
-
8
-
-
0036463681
-
Metabonomics: a platform for studying drug toxicity and gene function
-
Nicholson J.K., Connelly J., Lindon J.C., Holmes E. Metabonomics: a platform for studying drug toxicity and gene function. Nature Reviews Drug Discovery 2002, 1:153-161.
-
(2002)
Nature Reviews Drug Discovery
, vol.1
, pp. 153-161
-
-
Nicholson, J.K.1
Connelly, J.2
Lindon, J.C.3
Holmes, E.4
-
9
-
-
4444309760
-
Potential of metabolomics as a functional genomics tool
-
Bino R.J., Hall R.D., Fiehn O., et al. Potential of metabolomics as a functional genomics tool. Trends in Plant Science 2004, 9:418-425.
-
(2004)
Trends in Plant Science
, vol.9
, pp. 418-425
-
-
Bino, R.J.1
Hall, R.D.2
Fiehn, O.3
-
11
-
-
0043069547
-
Understanding 'global' systems biology: metabonomics and the continuum of metabolism
-
Nicholson J.K., Wilson I.D. Understanding 'global' systems biology: metabonomics and the continuum of metabolism. Nature Reviews Drug Discovery 2003, 2:668-676.
-
(2003)
Nature Reviews Drug Discovery
, vol.2
, pp. 668-676
-
-
Nicholson, J.K.1
Wilson, I.D.2
-
12
-
-
4444277707
-
Innovation - metabolite profiling: from diagnostics to systems biology
-
Fernie A.R., Trethewey R.N., Krotzky A.J., Willmitzer L. Innovation - metabolite profiling: from diagnostics to systems biology. Nature Reviews Molecular Cell Biology 2004, 5:763-769.
-
(2004)
Nature Reviews Molecular Cell Biology
, vol.5
, pp. 763-769
-
-
Fernie, A.R.1
Trethewey, R.N.2
Krotzky, A.J.3
Willmitzer, L.4
-
13
-
-
0036500993
-
Systems biology: a brief overview
-
Kitano H. Systems biology: a brief overview. Science 2002, 295:1662-1664.
-
(2002)
Science
, vol.295
, pp. 1662-1664
-
-
Kitano, H.1
-
18
-
-
17444404226
-
High resolution "ultra performance" liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies
-
Wilson I.D., Nicholson J.K., Castro-Perez J., et al. High resolution "ultra performance" liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies. Journal of Proteome Research 2005, 4:591-598.
-
(2005)
Journal of Proteome Research
, vol.4
, pp. 591-598
-
-
Wilson, I.D.1
Nicholson, J.K.2
Castro-Perez, J.3
-
20
-
-
0034368580
-
Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids
-
Lindon J.C., Nicholson J.K., Holmes E., Everett J.R. Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids. Concepts in Magnetic Resonance 2000, 12:289-320.
-
(2000)
Concepts in Magnetic Resonance
, vol.12
, pp. 289-320
-
-
Lindon, J.C.1
Nicholson, J.K.2
Holmes, E.3
Everett, J.R.4
-
21
-
-
33847377098
-
From exogenous to endogenous: the inevitable imprint of mass spectrometry in metabolomics
-
Want E.J., Nordstrom A., Morita H., Siuzdak G. From exogenous to endogenous: the inevitable imprint of mass spectrometry in metabolomics. Journal of Proteome Research 2007, 6:459-468.
-
(2007)
Journal of Proteome Research
, vol.6
, pp. 459-468
-
-
Want, E.J.1
Nordstrom, A.2
Morita, H.3
Siuzdak, G.4
-
22
-
-
66349087823
-
Spectroscopic and statistical techniques for information recovery in metabonomics and metabolomics
-
Lindon J.C., Nicholson J.K. Spectroscopic and statistical techniques for information recovery in metabonomics and metabolomics. Annual Review of Analytical Chemistry 2008, 1:45-69.
-
(2008)
Annual Review of Analytical Chemistry
, vol.1
, pp. 45-69
-
-
Lindon, J.C.1
Nicholson, J.K.2
-
24
-
-
33645671556
-
1H NMR spectroscopy based metabonomics for large-scale epidemiological research: the INTERMAP study
-
1H NMR spectroscopy based metabonomics for large-scale epidemiological research: the INTERMAP study. Analytical Chemistry 2006, 78:2199-2208.
-
(2006)
Analytical Chemistry
, vol.78
, pp. 2199-2208
-
-
Dumas, M.E.1
Maibaum, E.C.2
Teague, C.3
-
25
-
-
20044368617
-
GC-MS libraries for the rapid identification of metabolites in complex biological samples
-
Schauer N., Steinhauser D., Strelkov S., et al. GC-MS libraries for the rapid identification of metabolites in complex biological samples. FEBS Letters 2005, 579:1332-1337.
-
(2005)
FEBS Letters
, vol.579
, pp. 1332-1337
-
-
Schauer, N.1
Steinhauser, D.2
Strelkov, S.3
-
26
-
-
1542408614
-
A strategy for identifying differences in large series of metabolomic samples analyzed by GC/MS
-
Jonsson P., Gullberg J., Nordstrom A., et al. A strategy for identifying differences in large series of metabolomic samples analyzed by GC/MS. Analytical Chemistry 2004, 76:1738-1745.
-
(2004)
Analytical Chemistry
, vol.76
, pp. 1738-1745
-
-
Jonsson, P.1
Gullberg, J.2
Nordstrom, A.3
-
27
-
-
34248580879
-
Gas chromatography mass spectrometry-based metabolite profiling in plants
-
Lisec J., Schauer N., Kopka J., Willmitzer L., Fernie A.R. Gas chromatography mass spectrometry-based metabolite profiling in plants. Nature Protocols 2006, 1:387-396.
-
(2006)
Nature Protocols
, vol.1
, pp. 387-396
-
-
Lisec, J.1
Schauer, N.2
Kopka, J.3
Willmitzer, L.4
Fernie, A.R.5
-
28
-
-
33646743247
-
Nonlinear data alignment for UPLC-MS and HPLC-MS based metabolomics: quantitative analysis of endogenous and exogenous metabolites in human serum
-
Nordstrom A., O'Maille G., Qin C., Siuzdak G. Nonlinear data alignment for UPLC-MS and HPLC-MS based metabolomics: quantitative analysis of endogenous and exogenous metabolites in human serum. Analytical Chemistry 2006, 78:3289-3295.
-
(2006)
Analytical Chemistry
, vol.78
, pp. 3289-3295
-
-
Nordstrom, A.1
O'Maille, G.2
Qin, C.3
Siuzdak, G.4
-
29
-
-
22044449913
-
Strategy for metabonomics research based on high-performance liquid chromatography and liquid chromatography coupled with tandem mass spectrometry
-
Yang J., Xu G.W., Zheng W.F., et al. Strategy for metabonomics research based on high-performance liquid chromatography and liquid chromatography coupled with tandem mass spectrometry. Journal of Chromatography A 2005, 1084:214-221.
-
(2005)
Journal of Chromatography A
, vol.1084
, pp. 214-221
-
-
Yang, J.1
Xu, G.W.2
Zheng, W.F.3
-
30
-
-
2342483689
-
1H NMR spectroscopy, HPLC-TOF/MS and chemometrics
-
1H NMR spectroscopy, HPLC-TOF/MS and chemometrics. Journal of Pharmaceutical and Biomedical Analysis 2004, 35:599-608.
-
(2004)
Journal of Pharmaceutical and Biomedical Analysis
, vol.35
, pp. 599-608
-
-
Lenz, E.M.1
Bright, J.2
Knight, R.3
Wilson, I.D.4
Major, H.5
-
31
-
-
0345168159
-
Monolithic silica-based capillary reversed-phase liquid chromatography/electrospray mass spectrometry for plant metabolomics
-
Tolstikov V.V., Lommen A., Nakanishi K., Tanaka N., Fiehn O. Monolithic silica-based capillary reversed-phase liquid chromatography/electrospray mass spectrometry for plant metabolomics. Analytical Chemistry 2003, 75:6737-6740.
-
(2003)
Analytical Chemistry
, vol.75
, pp. 6737-6740
-
-
Tolstikov, V.V.1
Lommen, A.2
Nakanishi, K.3
Tanaka, N.4
Fiehn, O.5
-
32
-
-
0242569355
-
Quantitative metabolome analysis using capillary electrophoresis mass spectrometry
-
Soga T., Ohashi Y., Ueno Y., et al. Quantitative metabolome analysis using capillary electrophoresis mass spectrometry. Journal of Proteome Research 2003, 2:488-494.
-
(2003)
Journal of Proteome Research
, vol.2
, pp. 488-494
-
-
Soga, T.1
Ohashi, Y.2
Ueno, Y.3
-
33
-
-
74049156423
-
Metabolomics of transgenic maize combining Fourier transform-ion cyclotron resonance-mass spectrometry, capillary electrophoresis-mass spectrometry and pressurized liquid extraction
-
Leon C., Rodriguez-Meizoso I., Lucio M., et al. Metabolomics of transgenic maize combining Fourier transform-ion cyclotron resonance-mass spectrometry, capillary electrophoresis-mass spectrometry and pressurized liquid extraction. Journal of Chromatography A 2009, 1216:7314-7323.
-
(2009)
Journal of Chromatography A
, vol.1216
, pp. 7314-7323
-
-
Leon, C.1
Rodriguez-Meizoso, I.2
Lucio, M.3
-
35
-
-
45849120634
-
Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: a prospective blinded pilot study
-
Scott R., Seli E., Miller K., et al. Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: a prospective blinded pilot study. Fertility and Sterility 2008, 90:77-83.
-
(2008)
Fertility and Sterility
, vol.90
, pp. 77-83
-
-
Scott, R.1
Seli, E.2
Miller, K.3
-
36
-
-
33746449986
-
Metabolic fingerprinting in disease diagnosis: biomedical applications of infrared and Raman spectroscopy
-
Ellis D.I., Goodacre R. Metabolic fingerprinting in disease diagnosis: biomedical applications of infrared and Raman spectroscopy. Analyst 2006, 131:875-885.
-
(2006)
Analyst
, vol.131
, pp. 875-885
-
-
Ellis, D.I.1
Goodacre, R.2
-
37
-
-
72249110521
-
Development of a novel, FTIR (Fourier transform infrared spectroscopy) based, yeast bioassay for toxicity testing and stress response study
-
Corte L., Rellini P., Roscini L., Fatichenti F., Cardinali G. Development of a novel, FTIR (Fourier transform infrared spectroscopy) based, yeast bioassay for toxicity testing and stress response study. Analytica Chimica Acta 2010, 659:258-265.
-
(2010)
Analytica Chimica Acta
, vol.659
, pp. 258-265
-
-
Corte, L.1
Rellini, P.2
Roscini, L.3
Fatichenti, F.4
Cardinali, G.5
-
38
-
-
44949262024
-
Metabolomic profiling by near-infrared spectroscopy as a tool to assess embryo viability: a novel, non-invasive method for embryo selection
-
Vergouw C.G., Botros L.L., Roos P., et al. Metabolomic profiling by near-infrared spectroscopy as a tool to assess embryo viability: a novel, non-invasive method for embryo selection. Human Reproduction 2008, 23:1499-1504.
-
(2008)
Human Reproduction
, vol.23
, pp. 1499-1504
-
-
Vergouw, C.G.1
Botros, L.L.2
Roos, P.3
-
39
-
-
68949211048
-
Complementary advanced techniques applied for plant and food authentication
-
Socaciu C., Ranga F., Fetea F., et al. Complementary advanced techniques applied for plant and food authentication. Czech Journal of Food Sciences 2009, 27:S70-S75.
-
(2009)
Czech Journal of Food Sciences
, vol.27
-
-
Socaciu, C.1
Ranga, F.2
Fetea, F.3
-
40
-
-
19144371287
-
NMR-based metabonomic approaches for evaluating physiological influences on biofluid composition
-
Bollard M.E., Stanley E.G., Lindon J.C., Nicholson J.K., Holmes E. NMR-based metabonomic approaches for evaluating physiological influences on biofluid composition. NMR in Biomedicine 2005, 18:143-162.
-
(2005)
NMR in Biomedicine
, vol.18
, pp. 143-162
-
-
Bollard, M.E.1
Stanley, E.G.2
Lindon, J.C.3
Nicholson, J.K.4
Holmes, E.5
-
41
-
-
33747019547
-
Centering, scaling, and transformations: improving the biological information content of metabolomics data
-
van den Berg R.A., Hoefsloot H.C., Westerhuis J.A., Smilde A.K., van der Werf M.J. Centering, scaling, and transformations: improving the biological information content of metabolomics data. BMC Genomics 2006, 7:142.
-
(2006)
BMC Genomics
, vol.7
, pp. 142
-
-
van den Berg, R.A.1
Hoefsloot, H.C.2
Westerhuis, J.A.3
Smilde, A.K.4
van der Werf, M.J.5
-
42
-
-
70049102530
-
Understanding the human salivary metabolome
-
Takeda I., Stretch C., Barnaby P., et al. Understanding the human salivary metabolome. NMR in Biomedicine 2009, 22:577-584.
-
(2009)
NMR in Biomedicine
, vol.22
, pp. 577-584
-
-
Takeda, I.1
Stretch, C.2
Barnaby, P.3
-
43
-
-
56649121905
-
Noninvasive metabolomic profiling of embryo culture media using proton nuclear magnetic resonance correlates with reproductive potential of embryos in women undergoing in vitro fertilization
-
Seli E., Botros L., Sakkas D., Burns D.H. Noninvasive metabolomic profiling of embryo culture media using proton nuclear magnetic resonance correlates with reproductive potential of embryos in women undergoing in vitro fertilization. Fertility and Sterility 2008, 90:2183-2189.
-
(2008)
Fertility and Sterility
, vol.90
, pp. 2183-2189
-
-
Seli, E.1
Botros, L.2
Sakkas, D.3
Burns, D.H.4
-
44
-
-
68549106304
-
1H NMR based metabonomics of human amniotic fluid for the metabolic characterization of fetus malformations
-
1H NMR based metabonomics of human amniotic fluid for the metabolic characterization of fetus malformations. Journal of Proteome Research 2009, 8:4144-4150.
-
(2009)
Journal of Proteome Research
, vol.8
, pp. 4144-4150
-
-
Graca, G.1
Duarte, I.F.2
Barros, A.S.3
-
46
-
-
33748354488
-
Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia
-
Holmes E., Tsang T.M., Huang J.T., et al. Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia. Public Library of Science Medicine 2006, 3:e327.
-
(2006)
Public Library of Science Medicine
, vol.3
-
-
Holmes, E.1
Tsang, T.M.2
Huang, J.T.3
-
47
-
-
58449083360
-
Concentration of blood and seminal plasma elements and their relationships with semen parameters in men with spinal cord injury
-
Salsabili N., Mehrsai A.R., Jalaie S. Concentration of blood and seminal plasma elements and their relationships with semen parameters in men with spinal cord injury. Andrologia 2009, 41:24-28.
-
(2009)
Andrologia
, vol.41
, pp. 24-28
-
-
Salsabili, N.1
Mehrsai, A.R.2
Jalaie, S.3
-
48
-
-
0242690435
-
Spectral editing and pattern recognition methods applied to high-resolution magic-angle spinning 1H nuclear magnetic resonance spectroscopy of liver tissues
-
Wang Y., Bollard M.E., Keun H., et al. Spectral editing and pattern recognition methods applied to high-resolution magic-angle spinning 1H nuclear magnetic resonance spectroscopy of liver tissues. Analytical Biochemistry 2003, 323:26-32.
-
(2003)
Analytical Biochemistry
, vol.323
, pp. 26-32
-
-
Wang, Y.1
Bollard, M.E.2
Keun, H.3
-
49
-
-
0036639485
-
NMR and pattern recognition studies on liver extracts and intact livers from rats treated with alpha-naphthylisothiocyanate
-
Waters N.J., Holmes E., Waterfield C.J., Farrant R.D., Nicholson J.K. NMR and pattern recognition studies on liver extracts and intact livers from rats treated with alpha-naphthylisothiocyanate. Biochem Pharmacol 2002, 64:67-77.
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 67-77
-
-
Waters, N.J.1
Holmes, E.2
Waterfield, C.J.3
Farrant, R.D.4
Nicholson, J.K.5
-
50
-
-
33645804032
-
Metabolic profiling of livers and blood from obese Zucker rats
-
Serkova N.J., Jackman M., Brown J.L., et al. Metabolic profiling of livers and blood from obese Zucker rats. Journal of Hepatology 2006, 44:956-962.
-
(2006)
Journal of Hepatology
, vol.44
, pp. 956-962
-
-
Serkova, N.J.1
Jackman, M.2
Brown, J.L.3
-
51
-
-
20844461344
-
H-NMR-based metabolic signatures of mild and severe ischemia/reperfusion injury in rat kidney transplants
-
Serkova N., Fuller T.F., Klawitter J., Freise C.E., Niemann C.U. H-NMR-based metabolic signatures of mild and severe ischemia/reperfusion injury in rat kidney transplants. Kidney International 2005, 67:1142-1151.
-
(2005)
Kidney International
, vol.67
, pp. 1142-1151
-
-
Serkova, N.1
Fuller, T.F.2
Klawitter, J.3
Freise, C.E.4
Niemann, C.U.5
-
53
-
-
38649108480
-
Species variation in the fecal metabolome gives insight into differential gastrointestinal function
-
Saric J., Wang Y., Li J., et al. Species variation in the fecal metabolome gives insight into differential gastrointestinal function. Journal of Proteome Research 2008, 7:352-360.
-
(2008)
Journal of Proteome Research
, vol.7
, pp. 352-360
-
-
Saric, J.1
Wang, Y.2
Li, J.3
-
54
-
-
33847378014
-
Rapid and noninvasive metabonomic characterization of inflammatory bowel disease
-
Marchesi J.R., Holmes E., Khan F., et al. Rapid and noninvasive metabonomic characterization of inflammatory bowel disease. Journal of Proteome Research 2007, 6:546-551.
-
(2007)
Journal of Proteome Research
, vol.6
, pp. 546-551
-
-
Marchesi, J.R.1
Holmes, E.2
Khan, F.3
-
55
-
-
48349115856
-
1H NMR metabolite profiling of feces as a tool to assess the impact of nutrition on the human microbiome
-
1H NMR metabolite profiling of feces as a tool to assess the impact of nutrition on the human microbiome. NMR in Biomedicine 2008, 21:615-626.
-
(2008)
NMR in Biomedicine
, vol.21
, pp. 615-626
-
-
Jacobs, D.M.1
Deltimple, N.2
van Velzen, E.3
-
56
-
-
34249870602
-
Clofibrate-induced changes in the liver, heart, brain and white adipose lipid metabolome of Swiss-Webster mice
-
Wheelock C.E., Goto S., Hammock B.D., Newman J.W. Clofibrate-induced changes in the liver, heart, brain and white adipose lipid metabolome of Swiss-Webster mice. Metabolomics 2007, 3:137-145.
-
(2007)
Metabolomics
, vol.3
, pp. 137-145
-
-
Wheelock, C.E.1
Goto, S.2
Hammock, B.D.3
Newman, J.W.4
-
57
-
-
0033795182
-
Metabonomics: evaluation of nuclear magnetic resonance (NMR) and pattern recognition technology for rapid in vivo screening of liver and kidney toxicants
-
Robertson D.G., Reily M.D., Sigler R.E., et al. Metabonomics: evaluation of nuclear magnetic resonance (NMR) and pattern recognition technology for rapid in vivo screening of liver and kidney toxicants. Toxicological Sciences 2000, 57:326-337.
-
(2000)
Toxicological Sciences
, vol.57
, pp. 326-337
-
-
Robertson, D.G.1
Reily, M.D.2
Sigler, R.E.3
-
60
-
-
0345270397
-
Plant metabolomics: large-scale phytochemistry in the functional genomics era
-
Sumner L.W., Mendes P., Dixon R.A. Plant metabolomics: large-scale phytochemistry in the functional genomics era. Phytochemistry 2003, 62:817-836.
-
(2003)
Phytochemistry
, vol.62
, pp. 817-836
-
-
Sumner, L.W.1
Mendes, P.2
Dixon, R.A.3
-
61
-
-
4444309760
-
Potential of metabolomics as a functional genomics tool
-
Bino R.J., Hall R.D., Fiehn O., et al. Potential of metabolomics as a functional genomics tool. Trends in Plant Science 2004, 9:418-425.
-
(2004)
Trends in Plant Science
, vol.9
, pp. 418-425
-
-
Bino, R.J.1
Hall, R.D.2
Fiehn, O.3
-
62
-
-
65249164096
-
1H NMR, GC-EI-TOFMS, and data set correlation for fruit metabolomics: application to spatial metabolite analysis in melon
-
1H NMR, GC-EI-TOFMS, and data set correlation for fruit metabolomics: application to spatial metabolite analysis in melon. Analytical Chemistry 2009, 81:2884-2894.
-
(2009)
Analytical Chemistry
, vol.81
, pp. 2884-2894
-
-
Biais, B.1
Allwood, J.W.2
Deborde, C.3
-
63
-
-
33144485880
-
Microbial metabolomics with gas chromatography/mass spectrometry
-
Koek M.M., Muilwijk B., van der Werf M.J. Microbial metabolomics with gas chromatography/mass spectrometry. Analytical Chemistry 2006, 78:1272-1281.
-
(2006)
Analytical Chemistry
, vol.78
, pp. 1272-1281
-
-
Koek, M.M.1
Muilwijk, B.2
van der Werf, M.J.3
-
65
-
-
1542375217
-
Ecotoxicogenomics: the challenge of integrating genomics into aquatic and terrestrial ecotoxicology
-
Snape J.R., Maund S.J., Pickford D.B., Hutchinson T.H. Ecotoxicogenomics: the challenge of integrating genomics into aquatic and terrestrial ecotoxicology. Aquatic Toxicology 2004, 67:143-154.
-
(2004)
Aquatic Toxicology
, vol.67
, pp. 143-154
-
-
Snape, J.R.1
Maund, S.J.2
Pickford, D.B.3
Hutchinson, T.H.4
-
66
-
-
45449111362
-
'Systems toxicology' approach identifies coordinated metabolic responses to copper in a terrestrial non-model invertebrate, the earthworm Lumbricus rubellus
-
Bundy J.G., Sidhu J.K., Rana F. 'Systems toxicology' approach identifies coordinated metabolic responses to copper in a terrestrial non-model invertebrate, the earthworm Lumbricus rubellus. Bmc Biology 2008, 6.
-
(2008)
Bmc Biology
, vol.6
-
-
Bundy, J.G.1
Sidhu, J.K.2
Rana, F.3
-
67
-
-
0032517858
-
The identification of novel biomarkers of renal toxicity using automatic data reduction techniques and PCA of proton NMR spectra of urine
-
Holmes E., Nicholson J.K., Nicholls A.W., et al. The identification of novel biomarkers of renal toxicity using automatic data reduction techniques and PCA of proton NMR spectra of urine. Chemometrics and Intelligent Laboratory Systems 1998, 44:245-255.
-
(1998)
Chemometrics and Intelligent Laboratory Systems
, vol.44
, pp. 245-255
-
-
Holmes, E.1
Nicholson, J.K.2
Nicholls, A.W.3
-
68
-
-
0025891393
-
Application of pattern-recognition methods to the analysis and classification of toxicological data derived from proton nuclear-magnetic-resonance spectroscopy of urine
-
Gartland K.P.R., Beddell C.R., Lindon J.C., Nicholson J.K. Application of pattern-recognition methods to the analysis and classification of toxicological data derived from proton nuclear-magnetic-resonance spectroscopy of urine. Molecular Pharmacology 1991, 39:629-642.
-
(1991)
Molecular Pharmacology
, vol.39
, pp. 629-642
-
-
Gartland, K.P.R.1
Beddell, C.R.2
Lindon, J.C.3
Nicholson, J.K.4
-
69
-
-
0028083271
-
Pattern-recognition classification of the site of nephrotoxicity based on metabolic data derived from proton nuclear-magnetic-resonance spectra of urine
-
Anthony M.L., Sweatman B.C., Beddell C.R., Lindon J.C., Nicholson J.K. Pattern-recognition classification of the site of nephrotoxicity based on metabolic data derived from proton nuclear-magnetic-resonance spectra of urine. Molecular Pharmacology 1994, 46:199-211.
-
(1994)
Molecular Pharmacology
, vol.46
, pp. 199-211
-
-
Anthony, M.L.1
Sweatman, B.C.2
Beddell, C.R.3
Lindon, J.C.4
Nicholson, J.K.5
-
70
-
-
72249110121
-
Self modeling curve resolution
-
Lawton W.H., Sylvestre A. Self modeling curve resolution. Technometrics 1971, 13:617-633.
-
(1971)
Technometrics
, vol.13
, pp. 617-633
-
-
Lawton, W.H.1
Sylvestre, A.2
-
71
-
-
46849110351
-
Self-modeling curve resolution: a new approach to recovering temporal metabolite signal modulation in NMR spectroscopic data: application to a life-long caloric restriction study in dogs
-
Richards S.E., Wang Y., Lawler D., et al. Self-modeling curve resolution: a new approach to recovering temporal metabolite signal modulation in NMR spectroscopic data: application to a life-long caloric restriction study in dogs. Analytical Chemistry 2008, 80:4876-4885.
-
(2008)
Analytical Chemistry
, vol.80
, pp. 4876-4885
-
-
Richards, S.E.1
Wang, Y.2
Lawler, D.3
-
72
-
-
0001129840
-
Multivariate curve resolution applied to spectral data from multiple runs of an industrial-process
-
Tauler R., Kowalski B., Fleming S. Multivariate curve resolution applied to spectral data from multiple runs of an industrial-process. Analytical Chemistry 1993, 65:2040-2047.
-
(1993)
Analytical Chemistry
, vol.65
, pp. 2040-2047
-
-
Tauler, R.1
Kowalski, B.2
Fleming, S.3
-
73
-
-
50549086569
-
Quantitative iterative target transformation factor analysis
-
Richards S.E., Walmsley A.D. Quantitative iterative target transformation factor analysis. Journal of Chemometrics 2007, 22:63-80.
-
(2007)
Journal of Chemometrics
, vol.22
, pp. 63-80
-
-
Richards, S.E.1
Walmsley, A.D.2
-
74
-
-
0035965479
-
Some recent developments in PLS modeling
-
Wold S., Trygg J., Berglund A., Antti H. Some recent developments in PLS modeling. Chemometrics and Intelligent Laboratory Systems 2001, 58:131-150.
-
(2001)
Chemometrics and Intelligent Laboratory Systems
, vol.58
, pp. 131-150
-
-
Wold, S.1
Trygg, J.2
Berglund, A.3
Antti, H.4
-
75
-
-
0032517819
-
Orthogonal signal correction of near-infrared spectra
-
Wold S., Antti H., Lindgren F., Ohman J. Orthogonal signal correction of near-infrared spectra. Chemometrics and Intelligent Laboratory Systems 1998, 44(175):185.
-
(1998)
Chemometrics and Intelligent Laboratory Systems
, vol.44
, Issue.175
, pp. 185
-
-
Wold, S.1
Antti, H.2
Lindgren, F.3
Ohman, J.4
-
76
-
-
0037163864
-
Physiological variation in metabolic phenotyping and functional genomic studies: use of orthogonal signal correction and PLS-DA
-
Gavaghan C.L., Wilson I.D., Nicholson J.K. Physiological variation in metabolic phenotyping and functional genomic studies: use of orthogonal signal correction and PLS-DA. FEBS Letters 2002, 530:191-196.
-
(2002)
FEBS Letters
, vol.530
, pp. 191-196
-
-
Gavaghan, C.L.1
Wilson, I.D.2
Nicholson, J.K.3
-
79
-
-
0036083139
-
Orthogonal projections to latent structures (O-PLS)
-
Trygg J., Wold S. Orthogonal projections to latent structures (O-PLS). Journal of Chemometrics 2002, 16:119-128.
-
(2002)
Journal of Chemometrics
, vol.16
, pp. 119-128
-
-
Trygg, J.1
Wold, S.2
-
80
-
-
0037282744
-
O2-PLS, a two-block (X-Y) latent variable regression (LVR) method with an integral OSC filter
-
Trygg J., Wold S. O2-PLS, a two-block (X-Y) latent variable regression (LVR) method with an integral OSC filter. Journal of Chemometrics 2003, 17:53-64.
-
(2003)
Journal of Chemometrics
, vol.17
, pp. 53-64
-
-
Trygg, J.1
Wold, S.2
-
81
-
-
0035107971
-
Metabonomic characterization of genetic variations in toxicological and metabolic responses using probabilistic neural networks
-
Holmes E., Nicholson J.K., Tranter G. Metabonomic characterization of genetic variations in toxicological and metabolic responses using probabilistic neural networks. Chemical Research in Toxicology 2001, 14:182-191.
-
(2001)
Chemical Research in Toxicology
, vol.14
, pp. 182-191
-
-
Holmes, E.1
Nicholson, J.K.2
Tranter, G.3
-
82
-
-
0037371851
-
Metabonomics classifies pathways affected by bioactive compounds. Artificial neural network classification of NMR spectra of plant extracts
-
Ott K.H., Aranibar N., Singh B.J., Stockton G.W. Metabonomics classifies pathways affected by bioactive compounds. Artificial neural network classification of NMR spectra of plant extracts. Phytochemistry 2003, 62:971-985.
-
(2003)
Phytochemistry
, vol.62
, pp. 971-985
-
-
Ott, K.H.1
Aranibar, N.2
Singh, B.J.3
Stockton, G.W.4
-
83
-
-
42149172522
-
K-OPLS package: kernel-based orthogonal projections to latent structures for prediction and interpretation in feature space
-
Bylesjo M., Rantalainen M., Nicholson J.K., Holmes E., Trygg J. K-OPLS package: kernel-based orthogonal projections to latent structures for prediction and interpretation in feature space. BMC Bioinformatics 2008, 9:106.
-
(2008)
BMC Bioinformatics
, vol.9
, pp. 106
-
-
Bylesjo, M.1
Rantalainen, M.2
Nicholson, J.K.3
Holmes, E.4
Trygg, J.5
-
84
-
-
84984286248
-
A PLS kernel algorithm for data sets with many variables and fewer objects. 1. Theory and algorithm
-
Rannar S., Lindgren F., Wold S. A PLS kernel algorithm for data sets with many variables and fewer objects. 1. Theory and algorithm. Journal of Chemometrics 1994, 8:111-125.
-
(1994)
Journal of Chemometrics
, vol.8
, pp. 111-125
-
-
Rannar, S.1
Lindgren, F.2
Wold, S.3
-
86
-
-
36348960223
-
Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the consortium on metabonomic toxicology screening approach
-
Ebbels T.M.D., Keun H.C., Beckonert O.P., et al. Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the consortium on metabonomic toxicology screening approach. Journal of Proteome Research 2007, 6:4407-4422.
-
(2007)
Journal of Proteome Research
, vol.6
, pp. 4407-4422
-
-
Ebbels, T.M.D.1
Keun, H.C.2
Beckonert, O.P.3
-
87
-
-
0142134307
-
Toxicity classification from metabonomic data using a density superposition approach: 'CLOUDS'
-
Ebbels T., Keun H., Beckonert O., et al. Toxicity classification from metabonomic data using a density superposition approach: 'CLOUDS'. Analytica Chimica Acta 2003, 490:109-122.
-
(2003)
Analytica Chimica Acta
, vol.490
, pp. 109-122
-
-
Ebbels, T.1
Keun, H.2
Beckonert, O.3
-
88
-
-
0028807247
-
Multivariate curve resolution applied to second order data
-
Tauler R. Multivariate curve resolution applied to second order data. Chemometrics and Intelligent Laboratory Systems 1995, 30:133-146.
-
(1995)
Chemometrics and Intelligent Laboratory Systems
, vol.30
, pp. 133-146
-
-
Tauler, R.1
-
90
-
-
33845429108
-
Review on multiway analysis in chemistry - 2000-2005
-
Bro R. Review on multiway analysis in chemistry - 2000-2005. Critical Reviews in Analytical Chemistry 2006, 36:279-293.
-
(2006)
Critical Reviews in Analytical Chemistry
, vol.36
, pp. 279-293
-
-
Bro, R.1
-
92
-
-
0001369487
-
Hierarchical multiblock PLS and PC models for easier model interpretation and as an alternative to variable selection
-
Wold S., Kettaneh N., Tjessem K. Hierarchical multiblock PLS and PC models for easier model interpretation and as an alternative to variable selection. Journal of Chemometrics 1996, 10:463-482.
-
(1996)
Journal of Chemometrics
, vol.10
, pp. 463-482
-
-
Wold, S.1
Kettaneh, N.2
Tjessem, K.3
-
96
-
-
70349267961
-
Metabolomics data exploration guided by prior knowledge
-
van den Berg R.A., Rubingh C.M., Westerhuis J.A., van der Werf M.J., Smilde A.K. Metabolomics data exploration guided by prior knowledge. Analytica Chimica Acta 2009, 651:173-181.
-
(2009)
Analytica Chimica Acta
, vol.651
, pp. 173-181
-
-
van den Berg, R.A.1
Rubingh, C.M.2
Westerhuis, J.A.3
van der Werf, M.J.4
Smilde, A.K.5
-
97
-
-
27144506971
-
Fusion of mass spectrometry-based metabolomics data
-
Smilde A.K., van der Werf M.J., Bijlsma S., van der Werff-van der Vat B.J., Jellema R.H. Fusion of mass spectrometry-based metabolomics data. Analytical Chemistry 2005, 77:6729-6736.
-
(2005)
Analytical Chemistry
, vol.77
, pp. 6729-6736
-
-
Smilde, A.K.1
van der Werf, M.J.2
Bijlsma, S.3
van der Werff-van der Vat, B.J.4
Jellema, R.H.5
-
98
-
-
59549100948
-
Matrix correlations for high-dimensional data: the modified RV-coefficient
-
Smilde A.K., Kiers H.A., Bijlsma S., Rubingh C.M., van Erk M.J. Matrix correlations for high-dimensional data: the modified RV-coefficient. Bioinformatics 2009, 25:401-405.
-
(2009)
Bioinformatics
, vol.25
, pp. 401-405
-
-
Smilde, A.K.1
Kiers, H.A.2
Bijlsma, S.3
Rubingh, C.M.4
van Erk, M.J.5
-
100
-
-
0035965470
-
Multiple factor analysis combined with PLS path modelling, application to the analysis of relationships between physicochemical variables, sensory profiles and hedonic judgements
-
Pages J., Tenenhaus M. Multiple factor analysis combined with PLS path modelling, application to the analysis of relationships between physicochemical variables, sensory profiles and hedonic judgements. Chemometrics and Intelligent laboratory systems 2001, 58:261-273.
-
(2001)
Chemometrics and Intelligent laboratory systems
, vol.58
, pp. 261-273
-
-
Pages, J.1
Tenenhaus, M.2
-
101
-
-
26844461471
-
Selection of biomarkers by a multivariate statistical processing of composite metabonomic data sets using multiple factor analysis
-
Dumas M.E., Canlet C., Debrauwer L., Martin P., Paris A. Selection of biomarkers by a multivariate statistical processing of composite metabonomic data sets using multiple factor analysis. Journal of Proteome Research 2005, 4:1485-1492.
-
(2005)
Journal of Proteome Research
, vol.4
, pp. 1485-1492
-
-
Dumas, M.E.1
Canlet, C.2
Debrauwer, L.3
Martin, P.4
Paris, A.5
-
102
-
-
70349279640
-
A structured overview of simultaneous component based data integration
-
Van Deun K., Smilde A.K., van der Werf M.J., Kiers H.A., Van Mechelen I. A structured overview of simultaneous component based data integration. BMC Bioinformatics 2009, 10:246.
-
(2009)
BMC Bioinformatics
, vol.10
, pp. 246
-
-
Van Deun, K.1
Smilde, A.K.2
van der Werf, M.J.3
Kiers, H.A.4
Van Mechelen, I.5
-
103
-
-
70549098154
-
Integrating functional genomics data using maximum likelihood based simultaneous component analysis
-
van den Berg R.A., Van Mechelen I., Wilderjans T.F., et al. Integrating functional genomics data using maximum likelihood based simultaneous component analysis. BMC Bioinformatics 2009, 10:1-12.
-
(2009)
BMC Bioinformatics
, vol.10
, pp. 1-12
-
-
van den Berg, R.A.1
Van Mechelen, I.2
Wilderjans, T.F.3
-
105
-
-
0013953617
-
Some mathematical notes on three-mode factor analysis
-
Tucker L.R. Some mathematical notes on three-mode factor analysis. Psychometrika 1966, 31:279-311.
-
(1966)
Psychometrika
, vol.31
, pp. 279-311
-
-
Tucker, L.R.1
-
106
-
-
0002332422
-
Principal component analysis of 3-mode data by means of alternating least-squares algorithms
-
Kroonenberg P.M., Deleeuw J. Principal component analysis of 3-mode data by means of alternating least-squares algorithms. Psychometrika 1980, 45:69-97.
-
(1980)
Psychometrika
, vol.45
, pp. 69-97
-
-
Kroonenberg, P.M.1
Deleeuw, J.2
-
107
-
-
0000311581
-
Some additional results on principal components-analysis of 3-mode data by means of alternating least-squares algorithms
-
Tenberge J.M.F., Deleeuw J., Kroonenberg P.M. Some additional results on principal components-analysis of 3-mode data by means of alternating least-squares algorithms. Psychometrika 1987, 52:183-191.
-
(1987)
Psychometrika
, vol.52
, pp. 183-191
-
-
Tenberge, J.M.F.1
Deleeuw, J.2
Kroonenberg, P.M.3
-
109
-
-
0028066826
-
N-way principal component analysis theory, algorithms and applications
-
Henrion R. N-way principal component analysis theory, algorithms and applications. Chemometrics and Intelligent Laboratory Systems 1994, 25:1-23.
-
(1994)
Chemometrics and Intelligent Laboratory Systems
, vol.25
, pp. 1-23
-
-
Henrion, R.1
-
110
-
-
14844327781
-
Multiway chemometric analysis of the metabolic response to toxins monitored by NMR
-
Dyrby M., Baunsgaard D., Bro R., Engelsen S.B. Multiway chemometric analysis of the metabolic response to toxins monitored by NMR. Chemometrics and Intelligent Laboratory Systems 2005, 76:79-89.
-
(2005)
Chemometrics and Intelligent Laboratory Systems
, vol.76
, pp. 79-89
-
-
Dyrby, M.1
Baunsgaard, D.2
Bro, R.3
Engelsen, S.B.4
-
111
-
-
4544326639
-
1H NMR-based urine metabolic profiles of male Wistar Han rats: implications for biomarker discovery
-
1H NMR-based urine metabolic profiles of male Wistar Han rats: implications for biomarker discovery. Biomarkers 2004, 9:156-179.
-
(2004)
Biomarkers
, vol.9
, pp. 156-179
-
-
Connor, S.C.1
Wu, W.2
Sweatman, B.C.3
-
112
-
-
2442517316
-
Multivariate approaches for efficient detection of potential metabolites from liquid chromatography/mass spectrometry data
-
Idborg H., Edlund P.O., Jacobsson S.P. Multivariate approaches for efficient detection of potential metabolites from liquid chromatography/mass spectrometry data. Rapid Commun Mass Spectrom 2004, 18:944-954.
-
(2004)
Rapid Commun Mass Spectrom
, vol.18
, pp. 944-954
-
-
Idborg, H.1
Edlund, P.O.2
Jacobsson, S.P.3
-
113
-
-
0003009442
-
Multiway calibration, multilinear PLS
-
Bro R. Multiway calibration, multilinear PLS. Journal of Chemometrics 1996, 10:47-61.
-
(1996)
Journal of Chemometrics
, vol.10
, pp. 47-61
-
-
Bro, R.1
-
114
-
-
13844276929
-
Analysis of lipoproteins using 2D diffusion-edited NMR spectroscopy and multi-way chemometrics
-
Dyrby M., Petersen M., Whittaker A.K., et al. Analysis of lipoproteins using 2D diffusion-edited NMR spectroscopy and multi-way chemometrics. Analytica Chimica Acta 2005, 531:209-216.
-
(2005)
Analytica Chimica Acta
, vol.531
, pp. 209-216
-
-
Dyrby, M.1
Petersen, M.2
Whittaker, A.K.3
-
115
-
-
33750738290
-
Generalized correlation loadings extending correlation loadings to congruence and to multi-way models
-
Lorho G., Westad F., Bro R. Generalized correlation loadings extending correlation loadings to congruence and to multi-way models. Chemometrics and Intelligent Laboratory Systems 2006, 84:119-125.
-
(2006)
Chemometrics and Intelligent Laboratory Systems
, vol.84
, pp. 119-125
-
-
Lorho, G.1
Westad, F.2
Bro, R.3
-
116
-
-
32444450572
-
ASCA: analysis of multivariate data obtained from an experimental design
-
Jansen J.J., Hoefsloot H.C.J., van der Greef J., et al. ASCA: analysis of multivariate data obtained from an experimental design. Journal of Chemometrics 2005, 19:469-481.
-
(2005)
Journal of Chemometrics
, vol.19
, pp. 469-481
-
-
Jansen, J.J.1
Hoefsloot, H.C.J.2
van der Greef, J.3
-
117
-
-
53649107769
-
PARAFASCA: ASCA combined with PARAFAC for the analysis of metabolic fingerprinting data
-
Jansen J.J., Bro R., Hoefsloot H.C.J., et al. PARAFASCA: ASCA combined with PARAFAC for the analysis of metabolic fingerprinting data. Journal of Chemometrics 2008, 22:114-121.
-
(2008)
Journal of Chemometrics
, vol.22
, pp. 114-121
-
-
Jansen, J.J.1
Bro, R.2
Hoefsloot, H.C.J.3
-
118
-
-
20044366919
-
Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets
-
Cloarec O., Dumas M.E., Craig A., et al. Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets. Analytical Chemistry 2005, 77:1282-1289.
-
(2005)
Analytical Chemistry
, vol.77
, pp. 1282-1289
-
-
Cloarec, O.1
Dumas, M.E.2
Craig, A.3
-
119
-
-
34247131764
-
Detection of urinary drug metabolite (xenometabolome) signatures in molecular epidemiology studies via statistical total correlation (NMR) spectroscopy
-
Holmes E., Loo R.L., Cloarec O., et al. Detection of urinary drug metabolite (xenometabolome) signatures in molecular epidemiology studies via statistical total correlation (NMR) spectroscopy. Analytical Chemistry 2007, 79:2629-2640.
-
(2007)
Analytical Chemistry
, vol.79
, pp. 2629-2640
-
-
Holmes, E.1
Loo, R.L.2
Cloarec, O.3
-
120
-
-
33745002268
-
Probing latent biomarker signatures and in vivo pathway activity in experimental disease states via statistical total correlation spectroscopy (STOCSY) of biofluids: application to HgCl2 toxicity
-
Holmes E., Cloarec O., Nicholson J.K. Probing latent biomarker signatures and in vivo pathway activity in experimental disease states via statistical total correlation spectroscopy (STOCSY) of biofluids: application to HgCl2 toxicity. Journal of Proteome Research 2006, 5:1313-1320.
-
(2006)
Journal of Proteome Research
, vol.5
, pp. 1313-1320
-
-
Holmes, E.1
Cloarec, O.2
Nicholson, J.K.3
-
121
-
-
46849112801
-
Kinetic and J-resolved statistical total correlation NMR spectroscopy approaches to structural information recovery in complex reacting mixtures: application to acyl glucuronide intramolecular transacylation reactions
-
Johnson C.H., Athersuch T.J., Wilson I.D., et al. Kinetic and J-resolved statistical total correlation NMR spectroscopy approaches to structural information recovery in complex reacting mixtures: application to acyl glucuronide intramolecular transacylation reactions. Analytical Chemistry 2008, 80:4886-4895.
-
(2008)
Analytical Chemistry
, vol.80
, pp. 4886-4895
-
-
Johnson, C.H.1
Athersuch, T.J.2
Wilson, I.D.3
-
122
-
-
72249097113
-
Metabonomic investigations into the global biochemical sequelae of exposure to the pancreatic toxin 1-cyano-2-hydroxy-3-butene in the rat
-
Bohus E., Racz A., Noszal B., et al. Metabonomic investigations into the global biochemical sequelae of exposure to the pancreatic toxin 1-cyano-2-hydroxy-3-butene in the rat. Magnetic Resonance in Chemistry 2009, 47:S26-S35.
-
(2009)
Magnetic Resonance in Chemistry
, vol.47
-
-
Bohus, E.1
Racz, A.2
Noszal, B.3
-
123
-
-
50149103744
-
Two-dimensional correlation analysis of nuclear magnetic resonance metabonomics data
-
Sasic S. Two-dimensional correlation analysis of nuclear magnetic resonance metabonomics data. Applied Spectroscopy 2008, 62:840-846.
-
(2008)
Applied Spectroscopy
, vol.62
, pp. 840-846
-
-
Sasic, S.1
-
124
-
-
36849083581
-
31P statistical total correlation NMR spectroscopy of intact liver for metabolic biomarker assignment: application to galactosamine-induced hepatotoxicity
-
31P statistical total correlation NMR spectroscopy of intact liver for metabolic biomarker assignment: application to galactosamine-induced hepatotoxicity. Analytical Chemistry 2007, 79:8956-8966.
-
(2007)
Analytical Chemistry
, vol.79
, pp. 8956-8966
-
-
Coen, M.1
Hong, Y.S.2
Cloarec, O.3
-
125
-
-
39449099306
-
31P heteronuclear statistical total correlation spectroscopy of intact human gut biopsies
-
31P heteronuclear statistical total correlation spectroscopy of intact human gut biopsies. Analytical Chemistry 2008, 80:1058-1066.
-
(2008)
Analytical Chemistry
, vol.80
, pp. 1058-1066
-
-
Wang, Y.1
Cloarec, O.2
Tang, H.3
-
126
-
-
39449113596
-
1H statistical total correlation spectroscopy as a tool in drug metabolism: study of flucloxacillin biotransformation
-
1H statistical total correlation spectroscopy as a tool in drug metabolism: study of flucloxacillin biotransformation. Analytical Chemistry 2008, 80:1073-1079.
-
(2008)
Analytical Chemistry
, vol.80
, pp. 1073-1079
-
-
Keun, H.C.1
Athersuch, T.J.2
Beckonert, O.3
-
127
-
-
51949105732
-
1H NMR and UPLC-MS(E) statistical heterospectroscopy: characterization of drug metabolites (xenometabolome) in epidemiological studies
-
1H NMR and UPLC-MS(E) statistical heterospectroscopy: characterization of drug metabolites (xenometabolome) in epidemiological studies. Analytical Chemistry 2008, 80:6835-6844.
-
(2008)
Analytical Chemistry
, vol.80
, pp. 6835-6844
-
-
Crockford, D.J.1
Maher, A.D.2
Ahmadi, K.R.3
-
128
-
-
30744443014
-
Statistical heterospectroscopy, an approach to the integrated analysis of NMR and UPLC-MS data sets: application in metabonomic toxicology studies
-
Crockford D.J., Holmes E., Lindon J.C., et al. Statistical heterospectroscopy, an approach to the integrated analysis of NMR and UPLC-MS data sets: application in metabonomic toxicology studies. Analytical Chemistry 2006, 78:363-371.
-
(2006)
Analytical Chemistry
, vol.78
, pp. 363-371
-
-
Crockford, D.J.1
Holmes, E.2
Lindon, J.C.3
-
129
-
-
75749140577
-
Bidirectional correlation of NMR and capillary electrophoresis fingerprints: a new approach to investigating Schistosoma mansoni infection in a mouse model
-
Garcia-Perez I., Alves A.C., Angulo S., et al. Bidirectional correlation of NMR and capillary electrophoresis fingerprints: a new approach to investigating Schistosoma mansoni infection in a mouse model. Analytical Chemistry 2010, 82:203-210.
-
(2010)
Analytical Chemistry
, vol.82
, pp. 203-210
-
-
Garcia-Perez, I.1
Alves, A.C.2
Angulo, S.3
-
130
-
-
0034775361
-
NMR and pattern recognition studies on the time-related metabolic effects of alpha-naphthylisothiocyanate on liver, urine, and plasma in the rat: an integrative metabonomic approach
-
Waters N.J., Holmes E., Williams A., et al. NMR and pattern recognition studies on the time-related metabolic effects of alpha-naphthylisothiocyanate on liver, urine, and plasma in the rat: an integrative metabonomic approach. Chemical Research in Toxicology 2001, 14:1401-1412.
-
(2001)
Chemical Research in Toxicology
, vol.14
, pp. 1401-1412
-
-
Waters, N.J.1
Holmes, E.2
Williams, A.3
-
131
-
-
17644369998
-
Metabonomic deconvolution of embedded toxicity: application to thioacetamide hepato- and nephrotoxicity
-
Waters N.J., Waterfield C.J., Farrant R.D., Holmes E., Nicholson J.K. Metabonomic deconvolution of embedded toxicity: application to thioacetamide hepato- and nephrotoxicity. Chemical Research in Toxicology 2005, 18:639-654.
-
(2005)
Chemical Research in Toxicology
, vol.18
, pp. 639-654
-
-
Waters, N.J.1
Waterfield, C.J.2
Farrant, R.D.3
Holmes, E.4
Nicholson, J.K.5
-
132
-
-
33750111733
-
An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate
-
Yap I.K., Clayton T.A., Tang H., et al. An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research 2006, 5:2675-2684.
-
(2006)
Journal of Proteome Research
, vol.5
, pp. 2675-2684
-
-
Yap, I.K.1
Clayton, T.A.2
Tang, H.3
-
133
-
-
13844250571
-
Integrated metabonomic analysis of the multiorgan effects of hydrazine toxicity in the rat
-
Garrod S., Bollard M.E., Nicholls A.W., et al. Integrated metabonomic analysis of the multiorgan effects of hydrazine toxicity in the rat. Chemical Research in Toxicology 2005, 18:115-122.
-
(2005)
Chemical Research in Toxicology
, vol.18
, pp. 115-122
-
-
Garrod, S.1
Bollard, M.E.2
Nicholls, A.W.3
-
134
-
-
73649083369
-
NMR-based metabolic profiling identifies biomarkers of liver regeneration following partial hepatectomy in the rat
-
Bollard M.E., Contel N.R., Ebbels T.M., et al. NMR-based metabolic profiling identifies biomarkers of liver regeneration following partial hepatectomy in the rat. Journal of Proteome Research 2010, 9:59-69.
-
(2010)
Journal of Proteome Research
, vol.9
, pp. 59-69
-
-
Bollard, M.E.1
Contel, N.R.2
Ebbels, T.M.3
-
135
-
-
53949089441
-
Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes
-
Claus S.P., Tsang T.M., Wang Y., et al. Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes. Molecular Systems Biology 2008, 4:219.
-
(2008)
Molecular Systems Biology
, vol.4
, pp. 219
-
-
Claus, S.P.1
Tsang, T.M.2
Wang, Y.3
-
137
-
-
47349114231
-
Top-down systems biology integration of conditional prebiotic modulated transgenomic interactions in a humanized microbiome mouse model
-
Martin F.P., Wang Y., Sprenger N., et al. Top-down systems biology integration of conditional prebiotic modulated transgenomic interactions in a humanized microbiome mouse model. Molecular Systems Biology 2008, 4:205.
-
(2008)
Molecular Systems Biology
, vol.4
, pp. 205
-
-
Martin, F.P.1
Wang, Y.2
Sprenger, N.3
-
138
-
-
71549121959
-
Metabolic effects of dark chocolate consumption on energy, gut microbiota, and stress-related metabolism in free-living subjects
-
Martin F.P., Rezzi S., Pere-Trepat E., et al. Metabolic effects of dark chocolate consumption on energy, gut microbiota, and stress-related metabolism in free-living subjects. Journal of Proteome Reseach 2009, 8:5568-5579.
-
(2009)
Journal of Proteome Reseach
, vol.8
, pp. 5568-5579
-
-
Martin, F.P.1
Rezzi, S.2
Pere-Trepat, E.3
-
139
-
-
39449120417
-
Correlation network analysis for data integration and biomarker selection
-
Adourian A., Jennings E., Balasubramanian R., et al. Correlation network analysis for data integration and biomarker selection. Molecular Biosystems 2008, 4:249-259.
-
(2008)
Molecular Biosystems
, vol.4
, pp. 249-259
-
-
Adourian, A.1
Jennings, E.2
Balasubramanian, R.3
-
140
-
-
59749103024
-
Metabolic profiling of a Schistosoma mansoni infection in mouse tissues using magic angle spinning-nuclear magnetic resonance spectroscopy
-
Li J.V., Holmes E., Saric J., et al. Metabolic profiling of a Schistosoma mansoni infection in mouse tissues using magic angle spinning-nuclear magnetic resonance spectroscopy. International Journal for Parasitology 2009, 39:547-558.
-
(2009)
International Journal for Parasitology
, vol.39
, pp. 547-558
-
-
Li, J.V.1
Holmes, E.2
Saric, J.3
-
142
-
-
0028483476
-
Monitoring batch processes using multiway principal component analysis
-
Nomikos P., MacGregor J.F. Monitoring batch processes using multiway principal component analysis. AICHE Journal 1994, 40:1361-1375.
-
(1994)
AICHE Journal
, vol.40
, pp. 1361-1375
-
-
Nomikos, P.1
MacGregor, J.F.2
-
143
-
-
37849020261
-
Network inference, analysis, and modeling in systems biology
-
Albert R. Network inference, analysis, and modeling in systems biology. Plant Cell 2007, 19:3327-3338.
-
(2007)
Plant Cell
, vol.19
, pp. 3327-3338
-
-
Albert, R.1
-
144
-
-
77949524119
-
VitisNet: "omics" integration through grapevine molecular networks
-
Grimplet J., Cramer G.R., Dickerson J.A., et al. VitisNet: "omics" integration through grapevine molecular networks. PLoS One 2009, 4:e8365.
-
(2009)
PLoS One
, vol.4
-
-
Grimplet, J.1
Cramer, G.R.2
Dickerson, J.A.3
-
145
-
-
0033982936
-
KEGG: kyoto encyclopedia of genes and genomes
-
Kanehisa M., Goto S. KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Research 2000, 28:27-30.
-
(2000)
Nucleic Acids Research
, vol.28
, pp. 27-30
-
-
Kanehisa, M.1
Goto, S.2
-
146
-
-
0034069495
-
Gene ontology: tool for the unification of biology. The Gene Ontology Consortium
-
Ashburner M., Ball C.A., Blake J.A., et al. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nature Genetics 2000, 25:25-29.
-
(2000)
Nature Genetics
, vol.25
, pp. 25-29
-
-
Ashburner, M.1
Ball, C.A.2
Blake, J.A.3
-
148
-
-
0033028596
-
Systematic determination of genetic network architecture
-
Tavazoie S., Hughes J.D., Campbell M.J., Cho R.J., Church G.M. Systematic determination of genetic network architecture. Nature Genetics 1999, 22:281-285.
-
(1999)
Nature Genetics
, vol.22
, pp. 281-285
-
-
Tavazoie, S.1
Hughes, J.D.2
Campbell, M.J.3
Cho, R.J.4
Church, G.M.5
-
149
-
-
0038054341
-
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
Mootha V.K., Lindgren C.M., Eriksson K.F., et al. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nature Genetics 2003, 34:267-273.
-
(2003)
Nature Genetics
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.F.3
-
152
-
-
0035733690
-
Correlation between transcriptome and interactome mapping data from Saccharomyces cerevisiae
-
Ge H., Liu Z., Church G.M., Vidal M. Correlation between transcriptome and interactome mapping data from Saccharomyces cerevisiae. Nature Genetics 2001, 29:482-486.
-
(2001)
Nature Genetics
, vol.29
, pp. 482-486
-
-
Ge, H.1
Liu, Z.2
Church, G.M.3
Vidal, M.4
-
153
-
-
0032943195
-
Grasping at molecular interactions and genetic networks in Drosophila melanogaster using FlyNets, an Internet database
-
Sanchez C., Lachaize C., Janody F., et al. Grasping at molecular interactions and genetic networks in Drosophila melanogaster using FlyNets, an Internet database. Nucleic Acids Research 1999, 27:89-94.
-
(1999)
Nucleic Acids Research
, vol.27
, pp. 89-94
-
-
Sanchez, C.1
Lachaize, C.2
Janody, F.3
-
154
-
-
33748352373
-
Multiple knockout analysis of genetic robustness in the yeast metabolic network
-
Deutscher D., Meilijson I., Kupiec M., Ruppin E. Multiple knockout analysis of genetic robustness in the yeast metabolic network. Nature Genetics 2006, 38:993-998.
-
(2006)
Nature Genetics
, vol.38
, pp. 993-998
-
-
Deutscher, D.1
Meilijson, I.2
Kupiec, M.3
Ruppin, E.4
-
155
-
-
51349092391
-
Network-based prediction of human tissue-specific metabolism
-
Shlomi T., Cabili M.N., Herrgard M.J., Palsson B.O., Ruppin E. Network-based prediction of human tissue-specific metabolism. Nature Biotechnology 2008, 26:1003-1010.
-
(2008)
Nature Biotechnology
, vol.26
, pp. 1003-1010
-
-
Shlomi, T.1
Cabili, M.N.2
Herrgard, M.J.3
Palsson, B.O.4
Ruppin, E.5
-
156
-
-
66249132328
-
Predicting metabolic biomarkers of human inborn errors of metabolism
-
Shlomi T., Cabili M.N., Ruppin E. Predicting metabolic biomarkers of human inborn errors of metabolism. Molecular Systems Biology 2009, 5:263.
-
(2009)
Molecular Systems Biology
, vol.5
, pp. 263
-
-
Shlomi, T.1
Cabili, M.N.2
Ruppin, E.3
-
158
-
-
44049089850
-
Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis
-
Kleemann R., Verschuren L., van Erk M.J., et al. Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis. Genome Biology 2007, 8:R200.
-
(2007)
Genome Biology
, vol.8
-
-
Kleemann, R.1
Verschuren, L.2
van Erk, M.J.3
-
159
-
-
20844437901
-
Methods for the differential integrative omic analysis of plasma from a transgenic disease animal model
-
Davidov E., Clish C.B., Oresic M., et al. Methods for the differential integrative omic analysis of plasma from a transgenic disease animal model. Omics 2004, 8:267-288.
-
(2004)
Omics
, vol.8
, pp. 267-288
-
-
Davidov, E.1
Clish, C.B.2
Oresic, M.3
-
160
-
-
11144355343
-
Integrative biological analysis of the APOE*3-leiden transgenic mouse
-
Clish C.B., Davidov E., Oresic M., et al. Integrative biological analysis of the APOE*3-leiden transgenic mouse. Omics 2004, 8:3-13.
-
(2004)
Omics
, vol.8
, pp. 3-13
-
-
Clish, C.B.1
Davidov, E.2
Oresic, M.3
-
161
-
-
3142661160
-
An integrated reverse functional genomic and metabolic approach to understanding orotic acid-induced fatty liver
-
Griffin J.L., Bonney S.A., Mann C., et al. An integrated reverse functional genomic and metabolic approach to understanding orotic acid-induced fatty liver. Physiol Genomics 2004, 17:140-149.
-
(2004)
Physiol Genomics
, vol.17
, pp. 140-149
-
-
Griffin, J.L.1
Bonney, S.A.2
Mann, C.3
-
162
-
-
33750093232
-
Statistically integrated metabonomic-proteomic studies on a human prostate cancer xenograft model in mice
-
Rantalainen M., Cloarec O., Beckonert O., et al. Statistically integrated metabonomic-proteomic studies on a human prostate cancer xenograft model in mice. Journal of Proteome Research 2006, 5:2642-2655.
-
(2006)
Journal of Proteome Research
, vol.5
, pp. 2642-2655
-
-
Rantalainen, M.1
Cloarec, O.2
Beckonert, O.3
-
163
-
-
36949021555
-
Data integration in plant biology: the O2PLS method for combined modeling of transcript and metabolite data
-
Bylesjo M., Eriksson D., Kusano M., Moritz T., Trygg J. Data integration in plant biology: the O2PLS method for combined modeling of transcript and metabolite data. The Plant Journal 2007, 52:1181-1191.
-
(2007)
The Plant Journal
, vol.52
, pp. 1181-1191
-
-
Bylesjo, M.1
Eriksson, D.2
Kusano, M.3
Moritz, T.4
Trygg, J.5
-
164
-
-
60849098774
-
Integrated analysis of transcript, protein and metabolite data to study lignin biosynthesis in hybrid aspen
-
Bylesjo M., Nilsson R., Srivastava V., et al. Integrated analysis of transcript, protein and metabolite data to study lignin biosynthesis in hybrid aspen. Journal of Proteome Research 2009, 8:199-210.
-
(2009)
Journal of Proteome Research
, vol.8
, pp. 199-210
-
-
Bylesjo, M.1
Nilsson, R.2
Srivastava, V.3
-
166
-
-
0035400051
-
Genetical genomics: the added value from segregation
-
Jansen R.C., Nap J.P. Genetical genomics: the added value from segregation. Trends in Genetics 2001, 17:388-391.
-
(2001)
Trends in Genetics
, vol.17
, pp. 388-391
-
-
Jansen, R.C.1
Nap, J.P.2
-
167
-
-
0037456823
-
Genetics of gene expression surveyed in maize, mouse and man
-
Schadt E.E., Monks S.A., Drake T.A., et al. Genetics of gene expression surveyed in maize, mouse and man. Nature 2003, 422:297-302.
-
(2003)
Nature
, vol.422
, pp. 297-302
-
-
Schadt, E.E.1
Monks, S.A.2
Drake, T.A.3
-
169
-
-
33750070372
-
Integrated sampling procedure for metabolome analysis
-
Schaub J., Schiesling C., Reuss M., Dauner M. Integrated sampling procedure for metabolome analysis. Biotechnology Progress 2006, 22:1434-1442.
-
(2006)
Biotechnology Progress
, vol.22
, pp. 1434-1442
-
-
Schaub, J.1
Schiesling, C.2
Reuss, M.3
Dauner, M.4
-
170
-
-
34247560771
-
Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models
-
Dumas M.E., Wilder S.P., Bihoreau M.T., et al. Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models. Nature Genetics 2007, 39:666-672.
-
(2007)
Nature Genetics
, vol.39
, pp. 666-672
-
-
Dumas, M.E.1
Wilder, S.P.2
Bihoreau, M.T.3
-
171
-
-
43749087841
-
Human metabolic phenotype diversity and its association with diet and blood pressure
-
Holmes E., Loo R.L., Stamler J., et al. Human metabolic phenotype diversity and its association with diet and blood pressure. Nature 2008, 453:396-400.
-
(2008)
Nature
, vol.453
, pp. 396-400
-
-
Holmes, E.1
Loo, R.L.2
Stamler, J.3
-
172
-
-
57149114936
-
Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum
-
Gieger C., Geistlinger L., Altmaier E., et al. Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. Public Library of Science Genetics 2008, 4:e1000282.
-
(2008)
Public Library of Science Genetics
, vol.4
-
-
Gieger, C.1
Geistlinger, L.2
Altmaier, E.3
-
173
-
-
75749134031
-
A genome-wide perspective of genetic variation in human metabolism
-
Illig T., Gieger C., Zhai G., et al. A genome-wide perspective of genetic variation in human metabolism. Nature Genetics 2010, 42:137-141.
-
(2010)
Nature Genetics
, vol.42
, pp. 137-141
-
-
Illig, T.1
Gieger, C.2
Zhai, G.3
-
174
-
-
59249096217
-
Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study
-
Tanaka T., Shen J., Abecasis G.R., et al. Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study. Public Library of Science Genetics 2009, 5:e1000338.
-
(2009)
Public Library of Science Genetics
, vol.5
-
-
Tanaka, T.1
Shen, J.2
Abecasis, G.R.3
-
175
-
-
59149100506
-
System-wide molecular evidence for phenotypic buffering in Arabidopsis
-
Fu J., Keurentjes J.J., Bouwmeester H., et al. System-wide molecular evidence for phenotypic buffering in Arabidopsis. Nature Genetics 2009, 41:166-167.
-
(2009)
Nature Genetics
, vol.41
, pp. 166-167
-
-
Fu, J.1
Keurentjes, J.J.2
Bouwmeester, H.3
-
176
-
-
77951108285
-
Metabolomics: towards understanding host-microbe interactions
-
Han J., Antunes L.C., Finlay B.B., Borchers C.H. Metabolomics: towards understanding host-microbe interactions. Future Microbiology 2010, 5:153-161.
-
(2010)
Future Microbiology
, vol.5
, pp. 153-161
-
-
Han, J.1
Antunes, L.C.2
Finlay, B.B.3
Borchers, C.H.4
|