The identification of novel biomarkers of renal toxicity using automatic data reduction techniques and PCA of proton NMR spectra of urine

Chemometrics and Intelligent Laboratory Systems

Volumn 44, Issue 1-2, 1998, Pages 245-255

  Holmes, Elaine ^a   Nicholson, Jeremy K ^a   Nicholls, Andrew W ^a   Lindon, John C ^a   Connor, Susan C ^b   Polley, Stephen ^b   Connelly, John ^b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

1H NMR spectroscopy; Nephrotoxin; Principal components analysis

Indexed keywords

AMPHOTERICIN B; CADMIUM CHLORIDE; CEFALORIDINE; CISPLATIN; DOXORUBICIN; FLUORIDE SODIUM; LEAD ACETATE; MERCURIC CHLORIDE; TOXIN; URANYL NITRATE;

ANALYTIC METHOD; ANIMAL MODEL; CONFERENCE PAPER; CONTROLLED STUDY; DRUG INDUCED DISEASE; INTRAPERITONEAL DRUG ADMINISTRATION; NEPHROTOXICITY; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; TISSUE SPECIFICITY; TOXICITY TESTING; URINALYSIS;

EID: 0032517858     PISSN: 01697439     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-7439(98)00110-5     Document Type: Conference Paper

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