-
1
-
-
0035901090
-
Inflammation and cancer: Back to Virchow?
-
Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet 2001;357:539-45.
-
(2001)
Lancet
, vol.357
, pp. 539-545
-
-
Balkwill, F.1
Mantovani, A.2
-
2
-
-
66549124166
-
Is complement good or bad for cancer patients? A new perspective on an old dilemma
-
Markiewski MM, Lambris JD. Is complement good or bad for cancer patients? A new perspective on an old dilemma. Trends Immunol 2009;30:286-92.
-
(2009)
Trends Immunol
, vol.30
, pp. 286-292
-
-
Markiewski, M.M.1
Lambris, J.D.2
-
3
-
-
34248141100
-
A cytokine-mediated link between innate immunity, inflammation, and cancer
-
Lin WW, Karin M. A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest 2007;117:1175-83.
-
(2007)
J Clin Invest
, vol.117
, pp. 1175-1183
-
-
Lin, W.W.1
Karin, M.2
-
4
-
-
0037180757
-
Inflammation and cancer
-
Coussens LM, Werb Z. Inflammation and cancer. Nature 2002;420:860-7.
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
5
-
-
54549115052
-
Cancer exploiting complement: A clue or an exception?
-
Loveland BE, Cebon J. Cancer exploiting complement: a clue or an exception? Nat Immunol 2008;9:1205-6.
-
(2008)
Nat Immunol
, vol.9
, pp. 1205-1206
-
-
Loveland, B.E.1
Cebon, J.2
-
6
-
-
43749102276
-
Immune surveillance: A balance between protumor and antitumor immunity
-
Ostrand-Rosenberg S. Immune surveillance: a balance between protumor and antitumor immunity. Curr Opin Genet Dev 2008;18:11-8.
-
(2008)
Curr Opin Genet Dev
, vol.18
, pp. 11-18
-
-
Ostrand-Rosenberg, S.1
-
7
-
-
17644388462
-
Role of C5a in inflammatory responses
-
Guo RF, Ward PA. Role of C5a in inflammatory responses. Annu Rev Immunol 2005;23:821-52.
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 821-852
-
-
Guo, R.F.1
Ward, P.A.2
-
8
-
-
0034861323
-
Anaphylatoxins and infectious and non-infectious inflammatory diseases
-
Kohl J. Anaphylatoxins and infectious and non-infectious inflammatory diseases. Mol Immunol 2001;38:175-87.
-
(2001)
Mol Immunol
, vol.38
, pp. 175-187
-
-
Kohl, J.1
-
10
-
-
0036852241
-
Cancer immunoediting: From immunosurveillance to tumor escape
-
Dunn GP, Bruce AT, Ikeda H, Old LJ, Schreiber RD. Cancer immunoediting: from immunosurveillance to tumor escape. Nat Immunol 2002;3:991-8.
-
(2002)
Nat Immunol
, vol.3
, pp. 991-998
-
-
Dunn, G.P.1
Bruce, A.T.2
Ikeda, H.3
Old, L.J.4
Schreiber, R.D.5
-
11
-
-
54549109936
-
Modulation of the antitumor immune response by complement
-
Markiewski MM, DeAngelis RA, Benencia F, et al. Modulation of the antitumor immune response by complement. Nat Immunol 2008;9:1225-35.
-
(2008)
Nat Immunol
, vol.9
, pp. 1225-1235
-
-
Markiewski, M.M.1
DeAngelis, R.A.2
Benencia, F.3
-
12
-
-
36048937343
-
Complement-targeted therapeutics
-
Ricklin D, Lambris JD. Complement-targeted therapeutics. Nat Biotechnol 2007;25:1265-75.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 1265-1275
-
-
Ricklin, D.1
Lambris, J.D.2
-
13
-
-
0033390443
-
Complement activation and inhibition in experimental models of arthritis
-
Linton SM, Morgan BP. Complement activation and inhibition in experimental models of arthritis. Mol Immunol 1999;36:905-14.
-
(1999)
Mol Immunol
, vol.36
, pp. 905-914
-
-
Linton, S.M.1
Morgan, B.P.2
-
14
-
-
0036699081
-
Complement in glomerulonephritis
-
Welch TR. Complement in glomerulonephritis. Nat Genet 2002;31:333-4.
-
(2002)
Nat Genet
, vol.31
, pp. 333-334
-
-
Welch, T.R.1
-
15
-
-
3242888948
-
The role of complement activation in atherosclerosis
-
Niculescu F, Rus H. The role of complement activation in atherosclerosis. Immunol Res 2004;30:73-80.
-
(2004)
Immunol Res
, vol.30
, pp. 73-80
-
-
Niculescu, F.1
Rus, H.2
-
16
-
-
2442678025
-
The anaphylatoxins bridge innate and adaptive immune responses in allergic asthma
-
Hawlisch H, Wills-Karp M, Karp CL, Kohl J. The anaphylatoxins bridge innate and adaptive immune responses in allergic asthma. Mol Immunol 2004;41:123-31.
-
(2004)
Mol Immunol
, vol.41
, pp. 123-131
-
-
Hawlisch, H.1
Wills-Karp, M.2
Karp, C.L.3
Kohl, J.4
-
17
-
-
0034739041
-
A role for the C3a anaphylatoxin receptor in the effector phase of asthma
-
Humbles AA, Lu B, Nilsson CA, et al. A role for the C3a anaphylatoxin receptor in the effector phase of asthma. Nature 2000;406:998-1001.
-
(2000)
Nature
, vol.406
, pp. 998-1001
-
-
Humbles, A.A.1
Lu, B.2
Nilsson, C.A.3
-
18
-
-
0031748566
-
Multiple sclerosis: In situ evidence for antibody- and complement-mediated demyelination
-
Storch MK, Piddlesden S, Haltia M, Iivanainen M, Morgan P, Lassmann H. Multiple sclerosis: in situ evidence for antibody- and complement-mediated demyelination. Ann Neurol 1998;43:465-71.
-
(1998)
Ann Neurol
, vol.43
, pp. 465-471
-
-
Storch, M.K.1
Piddlesden, S.2
Haltia, M.3
Iivanainen, M.4
Morgan, P.5
Lassmann, H.6
-
19
-
-
34548849117
-
The role of complement in inflammatory diseases from behind the scenes into the spotlight
-
Markiewski MM, Lambris JD. The role of complement in inflammatory diseases from behind the scenes into the spotlight. Am J Pathol 2007;171:715-27.
-
(2007)
Am J Pathol
, vol.171
, pp. 715-727
-
-
Markiewski, M.M.1
Lambris, J.D.2
-
20
-
-
0035810399
-
Complement. First of two parts
-
Walport MJ. Complement. First of two parts. N Engl J Med 2001;344:1058-66.
-
(2001)
N Engl J Med
, vol.344
, pp. 1058-1066
-
-
Walport, M.J.1
-
21
-
-
0035849176
-
Complement. Second of two parts
-
Walport MJ. Complement. Second of two parts. N Engl J Med 2001;344:1140-4.
-
(2001)
N Engl J Med
, vol.344
, pp. 1140-1144
-
-
Walport, M.J.1
-
22
-
-
0036774408
-
Complement: More than a 'guard' against invading pathogens?
-
Mastellos D, Lambris JD. Complement: more than a 'guard' against invading pathogens? Trends Immunol 2002;23:485-91.
-
(2002)
Trends Immunol
, vol.23
, pp. 485-491
-
-
Mastellos, D.1
Lambris, J.D.2
-
23
-
-
78651278807
-
The complement cascade as a mediator of tissue growth and regeneration
-
Rutkowski MJ, Sughrue ME, Kane AJ, Ahn BJ, Fang S, Parsa AT. The complement cascade as a mediator of tissue growth and regeneration. Inflamm Res 2010;59:897-905.
-
(2010)
Inflamm Res
, vol.59
, pp. 897-905
-
-
Rutkowski, M.J.1
Sughrue, M.E.2
Kane, A.J.3
Ahn, B.J.4
Fang, S.5
Parsa, A.T.6
-
24
-
-
78649330001
-
Complement and the central nervous system: Emerging roles in development, protection and regeneration
-
Epub 2010 Apr 20
-
Rutkowski MJ, Sughrue ME, Kane AJ, Mills SA, Fang S, Parsa AT. Complement and the central nervous system: emerging roles in development, protection and regeneration. Immunol Cell Biol. Epub 2010 Apr 20.
-
Immunol Cell Biol
-
-
Rutkowski, M.J.1
Sughrue, M.E.2
Kane, A.J.3
Mills, S.A.4
Fang, S.5
Parsa, A.T.6
-
25
-
-
9444283776
-
Molecular cloning and characterization of the human anaphylatoxin C3a receptor
-
Ames RS, Li Y, Sarau HM, et al. Molecular cloning and characterization of the human anaphylatoxin C3a receptor. J Biol Chem 1996;271:20231-4.
-
(1996)
J Biol Chem
, vol.271
, pp. 20231-20234
-
-
Ames, R.S.1
Li, Y.2
Sarau, H.M.3
-
26
-
-
0026078539
-
The chemotactic receptor for human C5a anaphylatoxin
-
Gerard NP, Gerard C. The chemotactic receptor for human C5a anaphylatoxin. Nature 1991;349:614-7. (Pubitemid 21912116)
-
(1991)
Nature
, vol.349
, Issue.6310
, pp. 614-617
-
-
Gerard, N.P.1
Gerard, C.2
-
27
-
-
0037103283
-
Complement c3a and c5a induce different signal transduction cascades in endothelial cells
-
Schraufstatter IU, Trieu K, Sikora L, Sriramarao P, DiScipio R. Complement c3a and c5a induce different signal transduction cascades in endothelial cells. J Immunol 2002;169:2102-10.
-
(2002)
J Immunol
, vol.169
, pp. 2102-2110
-
-
Schraufstatter, I.U.1
Trieu, K.2
Sikora, L.3
Sriramarao, P.4
DiScipio, R.5
-
28
-
-
0037871469
-
Regulation by complement C3a and C5a anaphylatoxins of cytokine production in human umbilical vein endothelial cells
-
Monsinjon T, Gasque P, Chan P, Ischenko A, Brady JJ, Fontaine MC. Regulation by complement C3a and C5a anaphylatoxins of cytokine production in human umbilical vein endothelial cells. FASEB J 2003;17:1003-14.
-
(2003)
FASEB J
, vol.17
, pp. 1003-1014
-
-
Monsinjon, T.1
Gasque, P.2
Chan, P.3
Ischenko, A.4
Brady, J.J.5
Fontaine, M.C.6
-
29
-
-
33749257848
-
CXCL12 and C5a trigger cell migration via a PAK1/2-p38α MAPK-MAPKAP-K2-27 pathway
-
Rousseau S, Dolado I, Beardmore V, et al. CXCL12 and C5a trigger cell migration via a PAK1/2-p38α MAPK-MAPKAP-K2-27 pathway. Cell Signal 2006;18:1897-905.
-
(2006)
Cell Signal
, vol.18
, pp. 1897-1905
-
-
Rousseau, S.1
Dolado, I.2
Beardmore, V.3
-
30
-
-
10644221290
-
Distinct regulation of C3a-induced MCP-1/CCL2 and RANTES/CCL5 production in human mast cells by extracellular signal regulated kinase and PI3 kinase
-
Venkatesha RT, Berla Thangam E, Zaidi AK, Ali H. Distinct regulation of C3a-induced MCP-1/CCL2 and RANTES/CCL5 production in human mast cells by extracellular signal regulated kinase and PI3 kinase. Mol Immunol 2005;42:581-7.
-
(2005)
Mol Immunol
, vol.42
, pp. 581-587
-
-
Venkatesha, R.T.1
Berla Thangam, E.2
Zaidi, A.K.3
Ali, H.4
-
31
-
-
66949144423
-
The regulation of liver cell survival by complement
-
Markiewski MM, DeAngelis RA, Strey CW, et al. The regulation of liver cell survival by complement. J Immunol 2009;182:5412-8.
-
(2009)
J Immunol
, vol.182
, pp. 5412-5418
-
-
Markiewski, M.M.1
DeAngelis, R.A.2
Strey, C.W.3
-
32
-
-
0036632368
-
The phosphatidylinositol 3-kinase AKT pathway in human cancer
-
Vivanco I, Sawyers CL. The phosphatidylinositol 3-kinase AKT pathway in human cancer. Nat Rev Cancer 2002;2:489-501.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
33
-
-
33750058023
-
Upstream of the mammalian target of rapamycin: Do all roads pass through mTOR?
-
Corradetti MN, Guan KL. Upstream of the mammalian target of rapamycin: do all roads pass through mTOR? Oncogene 2006;25:6347-60.
-
(2006)
Oncogene
, vol.25
, pp. 6347-6360
-
-
Corradetti, M.N.1
Guan, K.L.2
-
34
-
-
33947110020
-
C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a
-
Chen NJ, Mirtsos C, Suh D, et al. C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a. Nature 2007;446:203-7.
-
(2007)
Nature
, vol.446
, pp. 203-207
-
-
Chen, N.J.1
Mirtsos, C.2
Suh, D.3
-
35
-
-
77951250395
-
The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction
-
Bamberg CE, Mackay CR, Lee H, et al. The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction. J Biol Chem 285:7633-44.
-
J Biol Chem
, vol.285
, pp. 7633-7644
-
-
Bamberg, C.E.1
Mackay, C.R.2
Lee, H.3
-
36
-
-
23844434887
-
G(i)-protein-dependent inhibition of IL-12 production is mediated by activation of the phosphatidylinositol 3-kinase-protein 3 kinase B/Akt pathway and JNK
-
la Sala A, Gadina M, Kelsall BL. G(i)-protein-dependent inhibition of IL-12 production is mediated by activation of the phosphatidylinositol 3-kinase-protein 3 kinase B/Akt pathway and JNK. J Immunol 2005;175:2994-9.
-
(2005)
J Immunol
, vol.175
, pp. 2994-2999
-
-
La Sala, A.1
Gadina, M.2
Kelsall, B.L.3
-
37
-
-
0034635513
-
Polarization of chemoattractant receptor signaling during neutrophil chemotaxis
-
Servant G, Weiner OD, Herzmark P, Balla T, Sedat JW, Bourne HR. Polarization of chemoattractant receptor signaling during neutrophil chemotaxis. Science 2000;287:1037-40.
-
(2000)
Science
, vol.287
, pp. 1037-1040
-
-
Servant, G.1
Weiner, O.D.2
Herzmark, P.3
Balla, T.4
Sedat, J.W.5
Bourne, H.R.6
-
38
-
-
0035076597
-
Complement anaphylatoxin C5a neuroprotects through mitogen-activated protein kinase-dependent inhibition of caspase 3
-
Mukherjee P, Pasinetti GM. Complement anaphylatoxin C5a neuroprotects through mitogen-activated protein kinase-dependent inhibition of caspase 3. J Neurochem 2001;77:43-9.
-
(2001)
J Neurochem
, vol.77
, pp. 43-49
-
-
Mukherjee, P.1
Pasinetti, G.M.2
-
39
-
-
0021273420
-
Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
-
Ullrich A, Coussens L, Hayflick JS, et al. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature 1984;309:418-25.
-
(1984)
Nature
, vol.309
, pp. 418-425
-
-
Ullrich, A.1
Coussens, L.2
Hayflick, J.S.3
-
40
-
-
4344686677
-
Expression of a functional C5a receptor in regenerating hepatocytes and its involvement in a proliferative signaling pathway in rat
-
Daveau M, Benard M, Scotte M, et al. Expression of a functional C5a receptor in regenerating hepatocytes and its involvement in a proliferative signaling pathway in rat. J Immunol 2004;173:3418-24.
-
(2004)
J Immunol
, vol.173
, pp. 3418-3424
-
-
Daveau, M.1
Benard, M.2
Scotte, M.3
-
41
-
-
0029885318
-
Pertussis toxin-sensitive activation of phospholipase C by the C5a and fMet-Leu-Phe receptors
-
Jiang H, Kuang Y, Wu Y, Smrcka A, Simon MI, Wu D. Pertussis toxin-sensitive activation of phospholipase C by the C5a and fMet-Leu-Phe receptors. J Biol Chem 1996;271:13430-4.
-
(1996)
J Biol Chem
, vol.271
, pp. 13430-13434
-
-
Jiang, H.1
Kuang, Y.2
Wu, Y.3
Smrcka, A.4
Simon, M.I.5
Wu, D.6
-
42
-
-
0025348474
-
Complement C5a activation of phospholipase D in human neutrophils. A major route to the production of phosphatidates and diglycerides
-
Mullmann TJ, Siegel MI, Egan RW, Billah MM. Complement C5a activation of phospholipase D in human neutrophils. A major route to the production of phosphatidates and diglycerides. J Immunol 1990;144:1901-8.
-
(1990)
J Immunol
, vol.144
, pp. 1901-1908
-
-
Mullmann, T.J.1
Siegel, M.I.2
Egan, R.W.3
Billah, M.M.4
-
44
-
-
0035869453
-
Neuronal expression of a functional receptor for the C5a complement activation fragment
-
O'Barr SA, Caguioa J, Gruol D, et al. Neuronal expression of a functional receptor for the C5a complement activation fragment. J Immunol 2001;166:4154-62.
-
(2001)
J Immunol
, vol.166
, pp. 4154-4162
-
-
O'Barr, S.A.1
Caguioa, J.2
Gruol, D.3
-
45
-
-
9644280856
-
The quantitative role of alternative pathway amplification in classical pathway induced terminal complement activation
-
Harboe M, Ulvund G, Vien L, Fung M, Mollnes TE. The quantitative role of alternative pathway amplification in classical pathway induced terminal complement activation. Clin Exp Immunol 2004;138:439-46.
-
(2004)
Clin Exp Immunol
, vol.138
, pp. 439-446
-
-
Harboe, M.1
Ulvund, G.2
Vien, L.3
Fung, M.4
Mollnes, T.E.5
-
46
-
-
34548244437
-
Opinion paper: Stimulation of complement amplification or activation of the alternative pathway of complement?
-
Lutz HU, Fumia S, Schurtenberger C, Alaia V. Opinion paper: stimulation of complement amplification or activation of the alternative pathway of complement? Mol Immunol 2007;44:3862-5.
-
(2007)
Mol Immunol
, vol.44
, pp. 3862-3865
-
-
Lutz, H.U.1
Fumia, S.2
Schurtenberger, C.3
Alaia, V.4
-
49
-
-
0028173973
-
2+ deregulation on mitochondrial membrane potential and cell viability in nucleated cells following lytic complement attack
-
2+ deregulation on mitochondrial membrane potential and cell viability in nucleated cells following lytic complement attack. Cell Calcium 1994;15:217-27.
-
(1994)
Cell Calcium
, vol.15
, pp. 217-227
-
-
Papadimitriou, J.C.1
Phelps, P.C.2
Shin, M.L.3
Smith, M.W.4
Trump, B.F.5
-
50
-
-
0038693797
-
Beyond lysis: How complement influences cell fate
-
Lond
-
Cole DS, Morgan BP. Beyond lysis: how complement influences cell fate. Clin Sci (Lond) 2003;104:455-66.
-
(2003)
Clin Sci
, vol.104
, pp. 455-466
-
-
Cole, D.S.1
Morgan, B.P.2
-
51
-
-
11244264468
-
The role of c5b-9 terminal complement complex in activation of the cell cycle and transcription
-
Fosbrink M, Niculescu F, Rus H. The role of c5b-9 terminal complement complex in activation of the cell cycle and transcription. Immunol Res 2005;31:37-46.
-
(2005)
Immunol Res
, vol.31
, pp. 37-46
-
-
Fosbrink, M.1
Niculescu, F.2
Rus, H.3
-
52
-
-
0034838024
-
Mechanisms of signal transduction activated by sublytic assembly of terminal complement complexes on nucleated cells
-
Niculescu F, Rus H. Mechanisms of signal transduction activated by sublytic assembly of terminal complement complexes on nucleated cells. Immunol Res 2001;24:191-9.
-
(2001)
Immunol Res
, vol.24
, pp. 191-199
-
-
Niculescu, F.1
Rus, H.2
-
53
-
-
0027217325
-
Terminal complement complex C5b-9 stimulates mitogenesis in 3T3 cells
-
Halperin JA, Taratuska A, Nicholson-Weller A. Terminal complement complex C5b-9 stimulates mitogenesis in 3T3 cells. J Clin Invest 1993;91:1974-8.
-
(1993)
J Clin Invest
, vol.91
, pp. 1974-1978
-
-
Halperin, J.A.1
Taratuska, A.2
Nicholson-Weller, A.3
-
54
-
-
0035069143
-
Involvement of the ERK mitogen-activated protein kinase in cell resistance to complement-mediated lysis
-
Kraus S, Seger R, Fishelson Z. Involvement of the ERK mitogen-activated protein kinase in cell resistance to complement-mediated lysis. Clin Exp Immunol 2001;123:366-74.
-
(2001)
Clin Exp Immunol
, vol.123
, pp. 366-374
-
-
Kraus, S.1
Seger, R.2
Fishelson, Z.3
-
55
-
-
0032890247
-
Sublytic C5b-9 induces proliferation of human aortic smooth muscle cells: Role of mitogen activated protein kinase and phosphatidylinositol 3-kinase
-
Niculescu F, Badea T, Rus H. Sublytic C5b-9 induces proliferation of human aortic smooth muscle cells: role of mitogen activated protein kinase and phosphatidylinositol 3-kinase. Atherosclerosis 1999;142:47-56.
-
(1999)
Atherosclerosis
, vol.142
, pp. 47-56
-
-
Niculescu, F.1
Badea, T.2
Rus, H.3
-
56
-
-
0033066412
-
Tyrosine phosphorylation and activation of Janus kinase 1 and STAT3 by sublytic C5b-9 complement complex in aortic endothelial cells
-
DOI 10.1016/S0162-3109(99)00014-4, PII S0162310999000144
-
Niculescu F, Soane L, Badea T, Shin M, Rus H. Tyrosine phosphorylation and activation of Janus kinase 1 and STAT3 by sublytic C5b-9 complement complex in aortic endothelial cells. Immunopharmacology 1999;42:187-93. (Pubitemid 29322301)
-
(1999)
Immunopharmacology
, vol.42
, Issue.1-3
, pp. 187-193
-
-
Niculescu, F.1
Soane, L.2
Badea, T.3
Shin, M.4
Rus, H.5
-
57
-
-
0034032736
-
Terminal complement complexes concomitantly stimulate proliferation and rescue of Schwann cells from apoptosis
-
Dashiell SM, Rus H, Koski CL. Terminal complement complexes concomitantly stimulate proliferation and rescue of Schwann cells from apoptosis. Glia 2000;30:187-98.
-
(2000)
Glia
, vol.30
, pp. 187-198
-
-
Dashiell, S.M.1
Rus, H.2
Koski, C.L.3
-
58
-
-
0032500522
-
Molecular cloning and characterization of RGC-32, a novel gene induced by complement activation in oligodendrocytes
-
Badea TC, Niculescu FI, Soane L, Shin ML, Rus H. Molecular cloning and characterization of RGC-32, a novel gene induced by complement activation in oligodendrocytes. J Biol Chem 1998;273:26977-81.
-
(1998)
J Biol Chem
, vol.273
, pp. 26977-26981
-
-
Badea, T.C.1
Niculescu, F.I.2
Soane, L.3
Shin, M.L.4
Rus, H.5
-
59
-
-
0037016763
-
RGC-32 increases p34CDC2 kinase activity and entry of aortic smooth muscle cells into S-phase
-
Badea T, Niculescu F, Soane L, et al. RGC-32 increases p34CDC2 kinase activity and entry of aortic smooth muscle cells into S-phase. J Biol Chem 2002;277:502-8.
-
(2002)
J Biol Chem
, vol.277
, pp. 502-508
-
-
Badea, T.1
Niculescu, F.2
Soane, L.3
-
60
-
-
13844298274
-
Overexpression of RGC-32 in colon cancer and other tumors
-
Fosbrink M, Cudrici C, Niculescu F, et al. Overexpression of RGC-32 in colon cancer and other tumors. Exp Mol Pathol 2005;78:116-22.
-
(2005)
Exp Mol Pathol
, vol.78
, pp. 116-122
-
-
Fosbrink, M.1
Cudrici, C.2
Niculescu, F.3
-
61
-
-
0029929039
-
Sublytic complement attack induces cell cycle in oligodendrocytes
-
Rus HG, Niculescu F, Shin ML. Sublytic complement attack induces cell cycle in oligodendrocytes. J Immunol 1996;156:4892-900.
-
(1996)
J Immunol
, vol.156
, pp. 4892-4900
-
-
Rus, H.G.1
Niculescu, F.2
Shin, M.L.3
-
62
-
-
0036721605
-
Complement activates the c-Jun N-terminal kinase/stress-activated protein kinase in glomerular epithelial cells
-
Peng H, Takano T, Papillon J, Bijian K, Khadir A, Cybulsky AV. Complement activates the c-Jun N-terminal kinase/stress-activated protein kinase in glomerular epithelial cells. J Immunol 2002;169:2594-601.
-
(2002)
J Immunol
, vol.169
, pp. 2594-2601
-
-
Peng, H.1
Takano, T.2
Papillon, J.3
Bijian, K.4
Khadir, A.5
Cybulsky, A.V.6
-
63
-
-
0031134091
-
Activation of Ras and mitogen-activated protein kinase pathway by terminal complement complexes is G protein dependent
-
Niculescu F, Rus H, van Biesen T, Shin ML. Activation of Ras and mitogen-activated protein kinase pathway by terminal complement complexes is G protein dependent. J Immunol 1997;158:4405-12.
-
(1997)
J Immunol
, vol.158
, pp. 4405-4412
-
-
Niculescu, F.1
Rus, H.2
Van Biesen, T.3
Shin, M.L.4
-
64
-
-
0642309618
-
Sublytic terminal complement attack induces c-fos transcriptional activation in myotubes
-
Badea TD, Park JH, Soane L, et al. Sublytic terminal complement attack induces c-fos transcriptional activation in myotubes. J Neuroimmunol 2003;142:58-66.
-
(2003)
J Neuroimmunol
, vol.142
, pp. 58-66
-
-
Badea, T.D.1
Park, J.H.2
Soane, L.3
-
65
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
67
-
-
5044232017
-
Liver regeneration: From myth to mechanism
-
Taub R. Liver regeneration: from myth to mechanism. Nat Rev Mol Cell Biol 2004;5:836-47.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 836-847
-
-
Taub, R.1
-
69
-
-
21344435775
-
Mechanisms of disease: Insights into the emerging role of signal transducers and activators of transcription in cancer
-
Haura EB, Turkson J, Jove R. Mechanisms of disease: insights into the emerging role of signal transducers and activators of transcription in cancer. Nat Clin Pract Oncol 2005;2:315-24.
-
(2005)
Nat Clin Pract Oncol
, vol.2
, pp. 315-324
-
-
Haura, E.B.1
Turkson, J.2
Jove, R.3
-
70
-
-
0033011634
-
Expression of cytokines by human astrocytomas following stimulation by C3a and C5a anaphylatoxins: Specific increase in interleukin-6 mRNA expression
-
Sayah S, Ischenko AM, Zhakhov A, Bonnard AS, Fontaine M. Expression of cytokines by human astrocytomas following stimulation by C3a and C5a anaphylatoxins: specific increase in interleukin-6 mRNA expression. J Neurochem 1999;72:2426-36.
-
(1999)
J Neurochem
, vol.72
, pp. 2426-2436
-
-
Sayah, S.1
Ischenko, A.M.2
Zhakhov, A.3
Bonnard, A.S.4
Fontaine, M.5
-
71
-
-
0028014275
-
Terminal complement proteins C5b-9 release basic fibroblast growth factor and platelet-derived growth factor from endothelial cells
-
Benzaquen LR, Nicholson-Weller A, Halperin JA. Terminal complement proteins C5b-9 release basic fibroblast growth factor and platelet-derived growth factor from endothelial cells. J Exp Med 1994;179:985-92.
-
(1994)
J Exp Med
, vol.179
, pp. 985-992
-
-
Benzaquen, L.R.1
Nicholson-Weller, A.2
Halperin, J.A.3
-
72
-
-
0027440843
-
Basic fibroblast growth factor and transforming growth factor β-1: Synergistic mediators of angiogenesis in vitro
-
Gajdusek CM, Luo Z, Mayberg MR. Basic fibroblast growth factor and transforming growth factor β-1: synergistic mediators of angiogenesis in vitro. J Cell Physiol 1993;157:133-44.
-
(1993)
J Cell Physiol
, vol.157
, pp. 133-144
-
-
Gajdusek, C.M.1
Luo, Z.2
Mayberg, M.R.3
-
73
-
-
34248199915
-
Complement C5 mediates experimental tubulointerstitial fibrosis
-
Boor P, Konieczny A, Villa L, et al. Complement C5 mediates experimental tubulointerstitial fibrosis. J Am Soc Nephrol 2007;18:1508-15.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 1508-1515
-
-
Boor, P.1
Konieczny, A.2
Villa, L.3
-
74
-
-
10844231850
-
Role of complement and complement membrane attack complex in laser-induced choroidal neovascularization
-
Bora PS, Sohn JH, Cruz JM, et al. Role of complement and complement membrane attack complex in laser-induced choroidal neovascularization. J Immunol 2005;174:491-7.
-
(2005)
J Immunol
, vol.174
, pp. 491-497
-
-
Bora, P.S.1
Sohn, J.H.2
Cruz, J.M.3
-
75
-
-
53149145652
-
Complement C5 regulates the expression of insulin-like growth factor binding proteins in chronic experimental allergic encephalomyelitis
-
Cudrici C, Ito T, Zafranskaia E, et al. Complement C5 regulates the expression of insulin-like growth factor binding proteins in chronic experimental allergic encephalomyelitis. J Neuroimmunol 2008;203:94-103.
-
(2008)
J Neuroimmunol
, vol.203
, pp. 94-103
-
-
Cudrici, C.1
Ito, T.2
Zafranskaia, E.3
-
76
-
-
39749202804
-
Fibrotic mechanisms in idiopathic rapidly progressive glomerulonephritis: The role of TGF-β1 and C5b-9
-
Gionanlis L, Alexopoulos E, Papagianni A, Leontsini M, Memmos D. Fibrotic mechanisms in idiopathic rapidly progressive glomerulonephritis: the role of TGF-β1 and C5b-9. Ren Fail 2008;30:239-46.
-
(2008)
Ren Fail
, vol.30
, pp. 239-246
-
-
Gionanlis, L.1
Alexopoulos, E.2
Papagianni, A.3
Leontsini, M.4
Memmos, D.5
-
77
-
-
0034785348
-
TGF-β signaling in tumor suppression and cancer progression
-
Derynck R, Akhurst RJ, Balmain A. TGF-β signaling in tumor suppression and cancer progression. Nat Genet 2001;29:117-29.
-
(2001)
Nat Genet
, vol.29
, pp. 117-129
-
-
Derynck, R.1
Akhurst, R.J.2
Balmain, A.3
-
78
-
-
0023100052
-
Synthesis of messenger RNAs for transforming growth factors α and β and the epidermal growth factor receptor by human tumors
-
Derynck R, Goeddel DV, Ullrich A, et al. Synthesis of messenger RNAs for transforming growth factors α and β and the epidermal growth factor receptor by human tumors. Cancer Res 1987;47:707-12.
-
(1987)
Cancer Res
, vol.47
, pp. 707-712
-
-
Derynck, R.1
Goeddel, D.V.2
Ullrich, A.3
-
79
-
-
0004834166
-
Activation of growth factor secretion in tumorigenic states of breast cancer induced by 17 β-estradiol or v-Ha-ras oncogene
-
Dickson RB, Kasid A, Huff KK, et al. Activation of growth factor secretion in tumorigenic states of breast cancer induced by 17 β-estradiol or v-Ha-ras oncogene. Proc Natl Acad Sci U S A 1987;84:837-41.
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 837-841
-
-
Dickson, R.B.1
Kasid, A.2
Huff, K.K.3
-
80
-
-
34249854131
-
Response gene to complement 32, a novel regulator for transforming growth factor-β-induced smooth muscle differentiation of neural crest cells
-
Li F, Luo Z, Huang W, et al. Response gene to complement 32, a novel regulator for transforming growth factor-β-induced smooth muscle differentiation of neural crest cells. J Biol Chem 2007;282:10133-7.
-
(2007)
J Biol Chem
, vol.282
, pp. 10133-10137
-
-
Li, F.1
Luo, Z.2
Huang, W.3
-
81
-
-
66149130307
-
RGC-32 mediates transforming growth factor-β-induced epithelial-mesenchymal transition in human renal proximal tubular cells
-
Huang WY, Li ZG, Rus H, Wang X, Jose PA, Chen SY. RGC-32 mediates transforming growth factor-β-induced epithelial-mesenchymal transition in human renal proximal tubular cells. J Biol Chem 2009;284:9426-32.
-
(2009)
J Biol Chem
, vol.284
, pp. 9426-9432
-
-
Huang, W.Y.1
Li, Z.G.2
Rus, H.3
Wang, X.4
Jose, P.A.5
Chen, S.Y.6
-
82
-
-
0030175273
-
Hereditary deficiencies in complement C5 are associated with intensified neurodegenerative responses that implicate new roles for the C-system in neuronal and astrocytic functions
-
Pasinetti GM, Tocco G, Sakhi S, et al. Hereditary deficiencies in complement C5 are associated with intensified neurodegenerative responses that implicate new roles for the C-system in neuronal and astrocytic functions. Neurobiol Dis 1996;3:197-204.
-
(1996)
Neurobiol Dis
, vol.3
, pp. 197-204
-
-
Pasinetti, G.M.1
Tocco, G.2
Sakhi, S.3
-
83
-
-
0033562337
-
Complement-derived anaphylatoxin C5a protects against glutamate-mediated neurotoxicity
-
Osaka H, Mukherjee P, Aisen PS, Pasinetti GM. Complement-derived anaphylatoxin C5a protects against glutamate-mediated neurotoxicity. J Cell Biochem 1999;73:303-11.
-
(1999)
J Cell Biochem
, vol.73
, pp. 303-311
-
-
Osaka, H.1
Mukherjee, P.2
Aisen, P.S.3
Pasinetti, G.M.4
-
84
-
-
39649121460
-
Complement anaphylatoxin C5a neuroprotects through regulation of glutamate receptor subunit 2 in vitro and in vivo
-
Mukherjee P, Thomas S, Pasinetti GM. Complement anaphylatoxin C5a neuroprotects through regulation of glutamate receptor subunit 2 in vitro and in vivo. J Neuroinflammation 2008;5:5.
-
(2008)
J Neuroinflammation
, vol.5
, pp. 5
-
-
Mukherjee, P.1
Thomas, S.2
Pasinetti, G.M.3
-
85
-
-
2142817257
-
Effects of Complement C5 on Apoptosis in Experimental Autoimmune Encephalomyelitis
-
Niculescu T, Weerth S, Niculescu F, et al. Effects of complement C5 on apoptosis in experimental autoimmune encephalomyelitis. J Immunol 2004;172:5702-6. (Pubitemid 38542074)
-
(2004)
Journal of Immunology
, vol.172
, Issue.9
, pp. 5702-5706
-
-
Niculescu, T.1
Weerth, S.2
Niculescu, F.3
Cudrici, C.4
Rus, V.5
Raine, C.S.6
Shin, M.L.7
Rus, H.8
-
86
-
-
34248643719
-
The insulin-like growth factor system in multiple sclerosis
-
Chesik D, Wilczak N, De Keyser J. The insulin-like growth factor system in multiple sclerosis. Int Rev Neurobiol 2007;79:203-26.
-
(2007)
Int Rev Neurobiol
, vol.79
, pp. 203-226
-
-
Chesik, D.1
Wilczak, N.2
De Keyser, J.3
-
87
-
-
0037100228
-
Insulin-like growth factor binding proteins-1 and -2 differentially inhibit rat oligodendrocyte precursor cell survival and differentiation in vitro
-
Kuhl NM, De Keyser J, De Vries H, Hoekstra D. Insulin-like growth factor binding proteins-1 and -2 differentially inhibit rat oligodendrocyte precursor cell survival and differentiation in vitro. J Neurosci Res 2002;69:207-16.
-
(2002)
J Neurosci Res
, vol.69
, pp. 207-216
-
-
Kuhl, N.M.1
De Keyser, J.2
De Vries, H.3
Hoekstra, D.4
-
88
-
-
0035847643
-
Complement anaphylatoxin C3a is selectively protective against NMDA-induced neuronal cell death
-
van Beek J, Nicole O, Ali C, et al. Complement anaphylatoxin C3a is selectively protective against NMDA-induced neuronal cell death. Neuroreport 2001;12:289-93.
-
(2001)
Neuroreport
, vol.12
, pp. 289-293
-
-
Van Beek, J.1
Nicole, O.2
Ali, C.3
-
89
-
-
0034793956
-
Sublytic C5b-9-stimulated Schwann cell survival through PI 3-kinase-mediated phosphorylation of BAD
-
Hila S, Soane L, Koski CL. Sublytic C5b-9-stimulated Schwann cell survival through PI 3-kinase-mediated phosphorylation of BAD. Glia 2001;36:58-67.
-
(2001)
Glia
, vol.36
, pp. 58-67
-
-
Hila, S.1
Soane, L.2
Koski, C.L.3
-
90
-
-
0033485393
-
Inhibition of oligodendrocyte apoptosis by sublytic C5b-9 is associated with enhanced synthesis of bcl-2 and mediated by inhibition of caspase-3 activation
-
Soane L, Rus H, Niculescu F, Shin ML. Inhibition of oligodendrocyte apoptosis by sublytic C5b-9 is associated with enhanced synthesis of bcl-2 and mediated by inhibition of caspase-3 activation. J Immunol 1999;163:6132-8.
-
(1999)
J Immunol
, vol.163
, pp. 6132-6138
-
-
Soane, L.1
Rus, H.2
Niculescu, F.3
Shin, M.L.4
-
91
-
-
33644516274
-
C5b-9 terminal complex protects oligodendrocytes from apoptotic cell death by inhibiting caspase-8 processing and up-regulating FLIP
-
Cudrici C, Niculescu F, Jensen T, et al. C5b-9 terminal complex protects oligodendrocytes from apoptotic cell death by inhibiting caspase-8 processing and up-regulating FLIP. J Immunol 2006;176:3173-80.
-
(2006)
J Immunol
, vol.176
, pp. 3173-3180
-
-
Cudrici, C.1
Niculescu, F.2
Jensen, T.3
-
92
-
-
0035881950
-
C5b-9 terminal complement complex protects oligodendrocytes from death by regulating Bad through phosphatidylinositol 3-kinase/Akt pathway
-
Soane L, Cho HJ, Niculescu F, Rus H, Shin ML. C5b-9 terminal complement complex protects oligodendrocytes from death by regulating Bad through phosphatidylinositol 3-kinase/Akt pathway. J Immunol 2001;167:2305-11.
-
(2001)
J Immunol
, vol.167
, pp. 2305-2311
-
-
Soane, L.1
Cho, H.J.2
Niculescu, F.3
Rus, H.4
Shin, M.L.5
-
93
-
-
33750623514
-
Complement activation in autoimmune demyelination: Dual role in neuroinflammation and neuroprotection
-
Rus H, Cudrici C, Niculescu F, Shin ML. Complement activation in autoimmune demyelination: dual role in neuroinflammation and neuroprotection. J Neuroimmunol 2006;180:9-16.
-
(2006)
J Neuroimmunol
, vol.180
, pp. 9-16
-
-
Rus, H.1
Cudrici, C.2
Niculescu, F.3
Shin, M.L.4
-
94
-
-
0037927904
-
The terminal complement complex inhibits apoptosis in vascular smooth muscle cells by activating an autocrine IGF-1 loop
-
Zwaka TP, Torzewski J, Hoeflich A, et al. The terminal complement complex inhibits apoptosis in vascular smooth muscle cells by activating an autocrine IGF-1 loop. FASEB J 2003;17:1346-8.
-
(2003)
FASEB J
, vol.17
, pp. 1346-1348
-
-
Zwaka, T.P.1
Torzewski, J.2
Hoeflich, A.3
-
95
-
-
0032890051
-
Vascular endothelial growth factor: Molecular and biological aspects
-
Ferrara N. Vascular endothelial growth factor: molecular and biological aspects. Curr Top Microbiol Immunol 1999;237:1-30. (Pubitemid 28554856)
-
(1999)
Current Topics in Microbiology and Immunology
, vol.237
, pp. 1-30
-
-
Ferrara, N.1
-
96
-
-
0032519011
-
C1qRP, the C1q receptor that enhances phagocytosis, is detected specifically in human cells of myeloid lineage, endothelial cells, and platelets
-
Nepomuceno RR, Tenner AJ. C1qRP, the C1q receptor that enhances phagocytosis, is detected specifically in human cells of myeloid lineage, endothelial cells, and platelets. J Immunol 1998;160:1929-35.
-
(1998)
J Immunol
, vol.160
, pp. 1929-1935
-
-
Nepomuceno, R.R.1
Tenner, A.J.2
-
97
-
-
0033152381
-
The molecular characterization of the fetal stem cell marker AA4
-
Petrenko O, Beavis A, Klaine M, Kittappa R, Godin I, Lemischka IR. The molecular characterization of the fetal stem cell marker AA4. Immunity 1999;10:691-700.
-
(1999)
Immunity
, vol.10
, pp. 691-700
-
-
Petrenko, O.1
Beavis, A.2
Klaine, M.3
Kittappa, R.4
Godin, I.5
Lemischka, I.R.6
-
98
-
-
33144488589
-
Drusen complement components C3a and C5a promote choroidal neovascularization
-
Nozaki M, Raisler BJ, Sakurai E, et al. Drusen complement components C3a and C5a promote choroidal neovascularization. Proc Natl Acad Sci U S A 2006;103:2328-33.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 2328-2333
-
-
Nozaki, M.1
Raisler, B.J.2
Sakurai, E.3
-
99
-
-
0029870954
-
The war on cancer
-
Sporn MB. The war on cancer. Lancet 1996;347:1377-81.
-
(1996)
Lancet
, vol.347
, pp. 1377-1381
-
-
Sporn, M.B.1
-
100
-
-
0038581169
-
Changing neighbours, changing behaviour: Cell adhesion molecule-mediated signaling during tumour progression
-
Christofori G. Changing neighbours, changing behaviour: cell adhesion molecule-mediated signaling during tumour progression. EMBO J 2003;22:2318-23.
-
(2003)
EMBO J
, vol.22
, pp. 2318-2323
-
-
Christofori, G.1
-
101
-
-
11144279989
-
Early neoplastic progression is complement independent
-
de Visser KE, Korets LV, Coussens LM. Early neoplastic progression is complement independent. Neoplasia 2004;6:768-76.
-
(2004)
Neoplasia
, vol.6
, pp. 768-776
-
-
De Visser, K.E.1
Korets, L.V.2
Coussens, L.M.3
-
102
-
-
0026780644
-
Persistent complement activation on tumor cells in breast cancer
-
Niculescu F, Rus HG, Retegan M, Vlaicu R. Persistent complement activation on tumor cells in breast cancer. Am J Pathol 1992;140:1039-43.
-
(1992)
Am J Pathol
, vol.140
, pp. 1039-1043
-
-
Niculescu, F.1
Rus, H.G.2
Retegan, M.3
Vlaicu, R.4
-
103
-
-
0028263593
-
Protection of thyroid cancer cells by complement-regulatory factors
-
Yamakawa M, Yamada K, Tsuge T, et al. Protection of thyroid cancer cells by complement-regulatory factors. Cancer 1994;73:2808-17.
-
(1994)
Cancer
, vol.73
, pp. 2808-2817
-
-
Yamakawa, M.1
Yamada, K.2
Tsuge, T.3
-
104
-
-
0029859464
-
Identification of a 35 kD tumor-associated autoantigen in papillary thyroid carcinoma
-
Lucas SD, Ek B, Rask L, Rastad J, Akerstrom G, Juhlin C. Identification of a 35 kD tumor-associated autoantigen in papillary thyroid carcinoma. Anticancer Res 1996;16:2493-6.
-
(1996)
Anticancer Res
, vol.16
, pp. 2493-2496
-
-
Lucas, S.D.1
Ek, B.2
Rask, L.3
Rastad, J.4
Akerstrom, G.5
Juhlin, C.6
-
105
-
-
0027936818
-
Activity and activation of the complement system in patients being operated on for cancer of the colon
-
Baatrup G, Qvist N, Junker A, Larsen KE, Zimmermann-Nielsen C. Activity and activation of the complement system in patients being operated on for cancer of the colon. Eur J Surg 1994;160:503-10.
-
(1994)
Eur J Surg
, vol.160
, pp. 503-510
-
-
Baatrup, G.1
Qvist, N.2
Junker, A.3
Larsen, K.E.4
Zimmermann-Nielsen, C.5
-
106
-
-
3142678924
-
Increased activity of the mannan-binding lectin complement activation pathway in patients with colorectal cancer
-
Ytting H, Jensenius JC, Christensen IJ, Thiel S, Nielsen HJ. Increased activity of the mannan-binding lectin complement activation pathway in patients with colorectal cancer. Scand J Gastroenterol 2004;39:674-9.
-
(2004)
Scand J Gastroenterol
, vol.39
, pp. 674-679
-
-
Ytting, H.1
Jensenius, J.C.2
Christensen, I.J.3
Thiel, S.4
Nielsen, H.J.5
-
108
-
-
0033079605
-
The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene
-
Christofori G, Semb H. The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene. Trends Biochem Sci 1999;24:73-6.
-
(1999)
Trends Biochem Sci
, vol.24
, pp. 73-76
-
-
Christofori, G.1
Semb, H.2
-
109
-
-
62149135267
-
C3a mediates epithelial-to-mesenchymal transition in proteinuric nephropathy
-
Tang Z, Lu B, Hatch E, Sacks SH, Sheerin NS. C3a mediates epithelial-to-mesenchymal transition in proteinuric nephropathy. J Am Soc Nephrol 2009;20:593-603.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 593-603
-
-
Tang, Z.1
Lu, B.2
Hatch, E.3
Sacks, S.H.4
Sheerin, N.S.5
-
110
-
-
0036559535
-
Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis
-
Lopez T, Hanahan D. Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis. Cancer Cell 2002;1:339-53.
-
(2002)
Cancer Cell
, vol.1
, pp. 339-353
-
-
Lopez, T.1
Hanahan, D.2
-
111
-
-
0035899466
-
IGF-II induces rapid β-catenin relocation to the nucleus during epithelium to mesenchyme transition
-
Morali OG, Delmas V, Moore R, Jeanney C, Thiery JP, Larue L. IGF-II induces rapid β-catenin relocation to the nucleus during epithelium to mesenchyme transition. Oncogene 2001;20:4942-50.
-
(2001)
Oncogene
, vol.20
, pp. 4942-4950
-
-
Morali, O.G.1
Delmas, V.2
Moore, R.3
Jeanney, C.4
Thiery, J.P.5
Larue, L.6
-
112
-
-
0032534678
-
Expression of the third component of complement, C3, in regenerating limb blastema cells of urodeles
-
Del Rio-Tsonis K, Tsonis PA, Zarkadis IK, Tsagas AG, Lambris JD. Expression of the third component of complement, C3, in regenerating limb blastema cells of urodeles. J Immunol 1998;161:6819-24.
-
(1998)
J Immunol
, vol.161
, pp. 6819-6824
-
-
Del Rio-Tsonis, K.1
Tsonis, P.A.2
Zarkadis, I.K.3
Tsagas, A.G.4
Lambris, J.D.5
-
113
-
-
0344211828
-
Expression of complement 3 and complement 5 in newt limb and lens regeneration
-
Kimura Y, Madhavan M, Call MK, et al. Expression of complement 3 and complement 5 in newt limb and lens regeneration. J Immunol 2003;170:2331-9.
-
(2003)
J Immunol
, vol.170
, pp. 2331-2339
-
-
Kimura, Y.1
Madhavan, M.2
Call, M.K.3
-
115
-
-
5144222255
-
Complement: A unique innate immune sensor for danger signals
-
Gasque P. Complement: a unique innate immune sensor for danger signals. Mol Immunol 2004;41:1089-98.
-
(2004)
Mol Immunol
, vol.41
, pp. 1089-1098
-
-
Gasque, P.1
-
116
-
-
60349127531
-
Complement activation and inhibition: A delicate balance
-
Sjoberg AP, Trouw LA, Blom AM. Complement activation and inhibition: a delicate balance. Trends Immunol 2009;30:83-90.
-
(2009)
Trends Immunol
, vol.30
, pp. 83-90
-
-
Sjoberg, A.P.1
Trouw, L.A.2
Blom, A.M.3
-
117
-
-
25444482114
-
The extracellular matrix and inflammation: Fibromodulin activates the classical pathway of complement by directly binding C1q
-
Sjoberg A, Onnerfjord P, Morgelin M, Heinegard D, Blom AM. The extracellular matrix and inflammation: fibromodulin activates the classical pathway of complement by directly binding C1q. J Biol Chem 2005;280:32301-8.
-
(2005)
J Biol Chem
, vol.280
, pp. 32301-32308
-
-
Sjoberg, A.1
Onnerfjord, P.2
Morgelin, M.3
Heinegard, D.4
Blom, A.M.5
-
118
-
-
59249103181
-
Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation
-
Sjoberg AP, Manderson GA, Morgelin M, Day AJ, Heinegard D, Blom AM. Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation. Mol Immunol 2009;46:830-9.
-
(2009)
Mol Immunol
, vol.46
, pp. 830-839
-
-
Sjoberg, A.P.1
Manderson, G.A.2
Morgelin, M.3
Day, A.J.4
Heinegard, D.5
Blom, A.M.6
-
119
-
-
70349564335
-
Interactions of histidine-rich glycoprotein with immunoglobulins and proteins of the complement system
-
Manderson GA, Martin M, Onnerfjord P, et al. Interactions of histidine-rich glycoprotein with immunoglobulins and proteins of the complement system. Mol Immunol 2009;46:3388-98.
-
(2009)
Mol Immunol
, vol.46
, pp. 3388-3398
-
-
Manderson, G.A.1
Martin, M.2
Onnerfjord, P.3
-
120
-
-
63149095644
-
Complement inhibitor C4b-binding protein interacts directly with small glycoproteins of the extracellular matrix
-
Happonen KE, Sjoberg AP, Morgelin M, Heinegard D, Blom AM. Complement inhibitor C4b-binding protein interacts directly with small glycoproteins of the extracellular matrix. J Immunol 2009;182:1518-25.
-
(2009)
J Immunol
, vol.182
, pp. 1518-1525
-
-
Happonen, K.E.1
Sjoberg, A.P.2
Morgelin, M.3
Heinegard, D.4
Blom, A.M.5
-
121
-
-
25444512040
-
Interactions of the extracellular matrix proteoglycans decorin and biglycan with C1q and collectins
-
Groeneveld TW, Oroszlan M, Owens RT, et al. Interactions of the extracellular matrix proteoglycans decorin and biglycan with C1q and collectins. J Immunol 2005;175:4715-23.
-
(2005)
J Immunol
, vol.175
, pp. 4715-4723
-
-
Groeneveld, T.W.1
Oroszlan, M.2
Owens, R.T.3
-
122
-
-
0030715322
-
ECM and cell surface proteolysis: Regulating cellular ecology
-
Werb Z. ECM and cell surface proteolysis: regulating cellular ecology. Cell 1997;91:439-42.
-
(1997)
Cell
, vol.91
, pp. 439-442
-
-
Werb, Z.1
-
123
-
-
0030587432
-
Complement proteins are present in developing endochondral bone and may mediate cartilage cell death and vascularization
-
Andrades JA, Nimni ME, Becerra J, Eisenstein R, Davis M, Sorgente N. Complement proteins are present in developing endochondral bone and may mediate cartilage cell death and vascularization. Exp Cell Res 1996;227:208-13.
-
(1996)
Exp Cell Res
, vol.227
, pp. 208-213
-
-
Andrades, J.A.1
Nimni, M.E.2
Becerra, J.3
Eisenstein, R.4
Davis, M.5
Sorgente, N.6
-
124
-
-
0025376478
-
Degradation of type I and II collagen by human activated C1-s
-
Yamaguchi K, Sakiyama H, Matsumoto M, Moriya H, Sakiyama S. Degradation of type I and II collagen by human activated C1-s. FEBS Lett 1990;268:206-8.
-
(1990)
FEBS Lett
, vol.268
, pp. 206-208
-
-
Yamaguchi, K.1
Sakiyama, H.2
Matsumoto, M.3
Moriya, H.4
Sakiyama, S.5
-
125
-
-
0034721666
-
MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis
-
Coussens LM, Tinkle CL, Hanahan D, Werb Z. MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis. Cell 2000;103:481-90.
-
(2000)
Cell
, vol.103
, pp. 481-490
-
-
Coussens, L.M.1
Tinkle, C.L.2
Hanahan, D.3
Werb, Z.4
-
126
-
-
0036782035
-
MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis
-
Hiratsuka S, Nakamura K, Iwai S, et al. MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis. Cancer Cell 2002;2:289-300.
-
(2002)
Cancer Cell
, vol.2
, pp. 289-300
-
-
Hiratsuka, S.1
Nakamura, K.2
Iwai, S.3
-
127
-
-
0037192458
-
Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
-
Coussens LM, Fingleton B, Matrisian LM. Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science 2002;295:2387-92.
-
(2002)
Science
, vol.295
, pp. 2387-2392
-
-
Coussens, L.M.1
Fingleton, B.2
Matrisian, L.M.3
-
128
-
-
5444225991
-
Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis
-
Yang L, DeBusk LM, Fukuda K, et al. Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis. Cancer Cell 2004;6:409-21.
-
(2004)
Cancer Cell
, vol.6
, pp. 409-421
-
-
Yang, L.1
DeBusk, L.M.2
Fukuda, K.3
-
129
-
-
37049006066
-
Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumorbone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma
-
Melani C, Sangaletti S, Barazzetta FM, Werb Z, Colombo MP. Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumorbone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma. Cancer Res 2007;67:11438-46.
-
(2007)
Cancer Res
, vol.67
, pp. 11438-11446
-
-
Melani, C.1
Sangaletti, S.2
Barazzetta, F.M.3
Werb, Z.4
Colombo, M.P.5
-
130
-
-
65449147900
-
C3a and C5a are chemotactic factors for human mesenchymal stem cells, which cause prolonged ERK1/2 phosphorylation
-
Schraufstatter IU, Discipio RG, Zhao M, Khaldoyanidi SK. C3a and C5a are chemotactic factors for human mesenchymal stem cells, which cause prolonged ERK1/2 phosphorylation. J Immunol 2009;182:3827-36.
-
(2009)
J Immunol
, vol.182
, pp. 3827-3836
-
-
Schraufstatter, I.U.1
Discipio, R.G.2
Zhao, M.3
Khaldoyanidi, S.K.4
-
131
-
-
0038264433
-
Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1
-
Reca R, Mastellos D, Majka M, et al. Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1. Blood 2003;101:3784-93.
-
(2003)
Blood
, vol.101
, pp. 3784-3793
-
-
Reca, R.1
Mastellos, D.2
Majka, M.3
-
132
-
-
33645309347
-
Complement: A novel factor in basal and ischemia-induced neurogenesis
-
Rahpeymai Y, Hietala MA, Wilhelmsson U, et al. Complement: a novel factor in basal and ischemia-induced neurogenesis. EMBO J 2006;25:1364-74.
-
(2006)
EMBO J
, vol.25
, pp. 1364-1374
-
-
Rahpeymai, Y.1
Hietala, M.A.2
Wilhelmsson, U.3
-
133
-
-
72849120050
-
Complement-derived anaphylatoxin C3a regulates in vitro differentiation and migration of neural progenitor cells
-
Shinjyo N, Stahlberg A, Dragunow M, Pekny M, Pekna M. Complement-derived anaphylatoxin C3a regulates in vitro differentiation and migration of neural progenitor cells. Stem Cells 2009;27:2824-32.
-
(2009)
Stem Cells
, vol.27
, pp. 2824-2832
-
-
Shinjyo, N.1
Stahlberg, A.2
Dragunow, M.3
Pekny, M.4
Pekna, M.5
-
134
-
-
33745297408
-
New signals from the invasive front
-
Christofori G. New signals from the invasive front. Nature 2006;441:444-50.
-
(2006)
Nature
, vol.441
, pp. 444-450
-
-
Christofori, G.1
-
136
-
-
33747859659
-
Stromal fibroblasts in cancer: A novel tumor-promoting cell type
-
Orimo A, Weinberg RA. Stromal fibroblasts in cancer: a novel tumor-promoting cell type. Cell Cycle 2006;5:1597-601.
-
(2006)
Cell Cycle
, vol.5
, pp. 1597-1601
-
-
Orimo, A.1
Weinberg, R.A.2
-
137
-
-
0033215242
-
Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium
-
Olumi AF, Grossfeld GD, Hayward SW, Carroll PR, Tlsty TD, Cunha GR. Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium. Cancer Res 1999;59:5002-11.
-
(1999)
Cancer Res
, vol.59
, pp. 5002-5011
-
-
Olumi, A.F.1
Grossfeld, G.D.2
Hayward, S.W.3
Carroll, P.R.4
Tlsty, T.D.5
Cunha, G.R.6
-
138
-
-
64549145804
-
Mesenchymal stem cell transition to tumor-associated fibroblasts contributes to fibrovascular network expansion and tumor progression
-
Spaeth EL, Dembinski JL, Sasser AK, et al. Mesenchymal stem cell transition to tumor-associated fibroblasts contributes to fibrovascular network expansion and tumor progression. PLoS One 2009;4:e4992.
-
(2009)
PLoS One
, vol.4
-
-
Spaeth, E.L.1
Dembinski, J.L.2
Sasser, A.K.3
-
139
-
-
0017875328
-
C3b and c3d receptor sites on human fibroblasts derived from several human tissues
-
Ueki A, Fukushima Y, Hyodoh F, Kimoto T. C3b and c3d receptor sites on human fibroblasts derived from several human tissues. Virchows Arch B Cell Pathol 1978;27:155-7.
-
(1978)
Virchows Arch B Cell Pathol
, vol.27
, pp. 155-157
-
-
Ueki, A.1
Fukushima, Y.2
Hyodoh, F.3
Kimoto, T.4
-
140
-
-
0031031213
-
Expression of the receptor for complement C5a (CD88) is up-regulated on reactive astrocytes, microglia, and endothelial cells in the inflamed human central nervous system
-
Gasque P, Singhrao SK, Neal JW, Gotze O, Morgan BP. Expression of the receptor for complement C5a (CD88) is up-regulated on reactive astrocytes, microglia, and endothelial cells in the inflamed human central nervous system. Am J Pathol 1997;150:31-41.
-
(1997)
Am J Pathol
, vol.150
, pp. 31-41
-
-
Gasque, P.1
Singhrao, S.K.2
Neal, J.W.3
Gotze, O.4
Morgan, B.P.5
-
141
-
-
38049027265
-
Complement system is activated in stenotic aortic valves
-
Helske S, Oksjoki R, Lindstedt KA, et al. Complement system is activated in stenotic aortic valves. Atherosclerosis 2008;196:190-200.
-
(2008)
Atherosclerosis
, vol.196
, pp. 190-200
-
-
Helske, S.1
Oksjoki, R.2
Lindstedt, K.A.3
-
142
-
-
0031180570
-
Distribution of receptors of collagen and globular domains of C1q in human lung fibroblasts
-
Narayanan AS, Lurton J, Raghu G. Distribution of receptors of collagen and globular domains of C1q in human lung fibroblasts. Am J Respir Cell Mol Biol 1997;17:84-90.
-
(1997)
Am J Respir Cell Mol Biol
, vol.17
, pp. 84-90
-
-
Narayanan, A.S.1
Lurton, J.2
Raghu, G.3
-
143
-
-
34249752194
-
1 integrin: A novel collectin/C1q receptor
-
1 integrin: a novel collectin/C1q receptor. Immunobiology 2007;212:343-53.
-
(2007)
Immunobiology
, vol.212
, pp. 343-353
-
-
Zutter, M.M.1
Edelson, B.T.2
-
146
-
-
0041563779
-
Obstacles to cancer immunotherapy: Expression of membrane complement regulatory proteins (mCRPs) in tumors
-
Fishelson Z, Donin N, Zell S, Schultz S, Kirschfink M. Obstacles to cancer immunotherapy: expression of membrane complement regulatory proteins (mCRPs) in tumors. Mol Immunol 2003;40:109-23.
-
(2003)
Mol Immunol
, vol.40
, pp. 109-123
-
-
Fishelson, Z.1
Donin, N.2
Zell, S.3
Schultz, S.4
Kirschfink, M.5
-
147
-
-
0037316424
-
Complement resistance of human carcinoma cells depends on membrane regulatory proteins, protein kinases and sialic acid
-
Donin N, Jurianz K, Ziporen L, Schultz S, Kirschfink M, Fishelson Z. Complement resistance of human carcinoma cells depends on membrane regulatory proteins, protein kinases and sialic acid. Clin Exp Immunol 2003;131:254-63.
-
(2003)
Clin Exp Immunol
, vol.131
, pp. 254-263
-
-
Donin, N.1
Jurianz, K.2
Ziporen, L.3
Schultz, S.4
Kirschfink, M.5
Fishelson, Z.6
-
148
-
-
0033368042
-
Complement resistance of tumor cells: Basal and induced mechanisms
-
Jurianz K, Ziegler S, Garcia-Schuler H, et al. Complement resistance of tumor cells: basal and induced mechanisms. Mol Immunol 1999;36:929-39.
-
(1999)
Mol Immunol
, vol.36
, pp. 929-939
-
-
Jurianz, K.1
Ziegler, S.2
Garcia-Schuler, H.3
-
149
-
-
45549086969
-
Complement and cellular cytotoxicity in antibody therapy of cancer
-
Wang SY, Weiner G. Complement and cellular cytotoxicity in antibody therapy of cancer. Expert Opin Biol Ther 2008;8:759-68.
-
(2008)
Expert Opin Biol Ther
, vol.8
, pp. 759-768
-
-
Wang, S.Y.1
Weiner, G.2
-
150
-
-
0034670027
-
Cutting edge: Targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock
-
Kildsgaard J, Hollmann TJ, Matthews KW, Bian K, Murad F, Wetsel RA. Cutting edge: targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock. J Immunol 2000;165:5406-9.
-
(2000)
J Immunol
, vol.165
, pp. 5406-5409
-
-
Kildsgaard, J.1
Hollmann, T.J.2
Matthews, K.W.3
Bian, K.4
Murad, F.5
Wetsel, R.A.6
-
151
-
-
23644456320
-
C3a expressed in the central nervous system protects against LPS-induced shock
-
Boos L, Szalai AJ, Barnum SR. C3a expressed in the central nervous system protects against LPS-induced shock. Neurosci Lett 2005;387:68-71.
-
(2005)
Neurosci Lett
, vol.387
, pp. 68-71
-
-
Boos, L.1
Szalai, A.J.2
Barnum, S.R.3
-
152
-
-
0031781612
-
Both C3a and C3a(desArg) regulate interleukin-6 synthesis in human peripheral blood mononuclear cells
-
Takabayashi T, Vannier E, Burke JF, Tompkins RG, Gelfand JA, Clark BD. Both C3a and C3a(desArg) regulate interleukin-6 synthesis in human peripheral blood mononuclear cells. J Infect Dis 1998;177:1622-8.
-
(1998)
J Infect Dis
, vol.177
, pp. 1622-1628
-
-
Takabayashi, T.1
Vannier, E.2
Burke, J.F.3
Tompkins, R.G.4
Gelfand, J.A.5
Clark, B.D.6
-
153
-
-
0029974609
-
A new biologic role for C3a and C3a desArg: Regulation of TNF-α and IL-1 β synthesis
-
Takabayashi T, Vannier E, Clark BD, et al. A new biologic role for C3a and C3a desArg: regulation of TNF-α and IL-1 β synthesis. J Immunol 1996;156:3455-60.
-
(1996)
J Immunol
, vol.156
, pp. 3455-3460
-
-
Takabayashi, T.1
Vannier, E.2
Clark, B.D.3
-
154
-
-
71149101844
-
Cooperation of decay-accelerating factor and membrane cofactor protein in regulating survival of human cervical cancer cells
-
Gao LJ, Guo SY, Cai YQ, et al. Cooperation of decay-accelerating factor and membrane cofactor protein in regulating survival of human cervical cancer cells. BMC Cancer 2009;9:384.
-
(2009)
BMC Cancer
, vol.9
, pp. 384
-
-
Gao, L.J.1
Guo, S.Y.2
Cai, Y.Q.3
-
155
-
-
0037105426
-
Complement-induced impairment of innate immunity during sepsis
-
Huber-Lang MS, Younkin EM, Sarma JV, et al. Complement-induced impairment of innate immunity during sepsis. J Immunol 2002;169:3223-31.
-
(2002)
J Immunol
, vol.169
, pp. 3223-3231
-
-
Huber-Lang, M.S.1
Younkin, E.M.2
Sarma, J.V.3
-
156
-
-
33748450585
-
Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction
-
Girardi G, Yarilin D, Thurman JM, Holers VM, Salmon JE. Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction. J Exp Med 2006;203:2165-75.
-
(2006)
J Exp Med
, vol.203
, pp. 2165-2175
-
-
Girardi, G.1
Yarilin, D.2
Thurman, J.M.3
Holers, V.M.4
Salmon, J.E.5
-
157
-
-
78649482676
-
Complement-mediated inhibition of neovascularization reveals a point of convergence between innate immunity and angiogenesis
-
Epub 2010 Jul 12
-
Langer HF, Chung KJ, Orlova VV, et al. Complement-mediated inhibition of neovascularization reveals a point of convergence between innate immunity and angiogenesis. Blood. Epub 2010 Jul 12.
-
Blood
-
-
Langer, H.F.1
Chung, K.J.2
Orlova, V.V.3
-
158
-
-
0036147901
-
Enhancement of the complement activating capacity of 17-1A mAb to overcome the effect of membrane-bound complement regulatory proteins on colorectal carcinoma
-
Gelderman KA, Kuppen PJ, Bruin W, Fleuren GJ, Gorter A. Enhancement of the complement activating capacity of 17-1A mAb to overcome the effect of membrane-bound complement regulatory proteins on colorectal carcinoma. Eur J Immunol 2002;32:128-35.
-
(2002)
Eur J Immunol
, vol.32
, pp. 128-135
-
-
Gelderman, K.A.1
Kuppen, P.J.2
Bruin, W.3
Fleuren, G.J.4
Gorter, A.5
-
159
-
-
16544391809
-
β-Glucan enhanced killing of renal cell carcinoma micrometastases by monoclonal antibody G250 directed complement activation
-
Sier CF, Gelderman KA, Prins FA, Gorter A. β-Glucan enhanced killing of renal cell carcinoma micrometastases by monoclonal antibody G250 directed complement activation. Int J Cancer 2004;109:900-8.
-
(2004)
Int J Cancer
, vol.109
, pp. 900-908
-
-
Sier, C.F.1
Gelderman, K.A.2
Prins, F.A.3
Gorter, A.4
-
160
-
-
18944394199
-
C5a-mediated leukotriene B4-amplified neutrophil chemotaxis is essential in tumor immunotherapy facilitated by anti-tumor monoclonal antibody and β-glucan
-
Allendorf DJ, Yan J, Ross GD, et al. C5a-mediated leukotriene B4-amplified neutrophil chemotaxis is essential in tumor immunotherapy facilitated by anti-tumor monoclonal antibody and β-glucan. J Immunol 2005;174:7050-6.
-
(2005)
J Immunol
, vol.174
, pp. 7050-7056
-
-
Allendorf, D.J.1
Yan, J.2
Ross, G.D.3
|