The extracellular matrix and inflammation: Fibromodulin activates the classical pathway of complement by directly binding C1q

Journal of Biological Chemistry

Volumn 280, Issue 37, 2005, Pages 32301-32308

  Sjöberg, Andreas ^a   Önnerfjord, Patrik ^b   Mörgelin, Matthias ^b   Heinegård, Dick ^b   Blom, Anna M ^a  

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGICAL MEMBRANES; CARTILAGE; DEPOSITION; FLAMMABILITY; IMMUNOLOGY; SULFATE MINERALS;

EXTRACELLULAR MATRIX; FIBROMODULIN BINDS; IMMUNOGLOBULINS; INFLAMMATION; METAL IONS;

DISEASES;

ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C3B; COMPLEMENT COMPONENT C4B; COMPLEMENT FACTOR H; COMPLEMENT INHIBITOR; COMPLEMENT MEMBRANE ATTACK COMPLEX; FIBROMODULIN; IMMUNOGLOBULIN; IMMUNOGLOBULIN G; INTERLEUKIN 1; KERATAN SULFATE; METAL ION;

ARTHRITIS; ARTHROPATHY; ARTICLE; CARTILAGE; COMPLEMENT ACTIVATION; COMPLEMENT CLASSICAL PATHWAY; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HUMAN; INFLAMMATION; JOINT PROSTHESIS; PRIORITY JOURNAL; PROTEIN BINDING; SERUM;

COMPLEMENT ACTIVATION; COMPLEMENT C1Q; COMPLEMENT SYSTEM PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; GLYCOSYLATION; HUMANS; IMMUNOGLOBULIN G; INFLAMMATION; INTERLEUKIN-1; IONS; KERATAN SULFATE; MICROSCOPY, ELECTRON; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEOGLYCANS; SURFACE PLASMON RESONANCE; TIME FACTORS;

EID: 25444482114     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M504828200     Document Type: Article

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