메뉴 건너뛰기




Volumn 203, Issue 9, 2006, Pages 2165-2175

Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENIC FACTOR; COMPLEMENT COMPONENT C5A; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1;

EID: 33748450585     PISSN: 00221007     EISSN: 00221007     Source Type: Journal    
DOI: 10.1084/jem.20061022     Document Type: Article
Times cited : (428)

References (54)
  • 4
    • 0034097042 scopus 로고    scopus 로고
    • Immunology at the maternal-fetal interface: Lessons for T cell tolerance and suppression
    • Mellor, A.L., and D.H. Munn. 2000. Immunology at the maternal-fetal interface: lessons for T cell tolerance and suppression. Annu. Rev. Immunol. 18:367-391.
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 367-391
    • Mellor, A.L.1    Munn, D.H.2
  • 7
    • 0034695647 scopus 로고    scopus 로고
    • A critical role for murine complement regulator crry in fetomaternal tolerance
    • Xu, C., D. Mao, V.M. Holers, B. Palanca, A.M. Cheng, and H. Molina. 2000. A critical role for murine complement regulator crry in fetomaternal tolerance. Science. 287:498-501.
    • (2000) Science , vol.287 , pp. 498-501
    • Xu, C.1    Mao, D.2    Holers, V.M.3    Palanca, B.4    Cheng, A.M.5    Molina, H.6
  • 8
    • 1542287265 scopus 로고    scopus 로고
    • Regulatory T cells mediate maternal tolerance to the fetus
    • Aluvihare, V.R., M. Kallikourdis, and A.G. Betz. 2004. Regulatory T cells mediate maternal tolerance to the fetus. Nat. Immunol. 5:266-271.
    • (2004) Nat. Immunol. , vol.5 , pp. 266-271
    • Aluvihare, V.R.1    Kallikourdis, M.2    Betz, A.G.3
  • 9
    • 0035221101 scopus 로고    scopus 로고
    • Prevention of T cell-driven complement activation and inflammation by tryptophan catabolism during pregnancy
    • Mellor, A.L., J. Sivakumar, P. Chandler, K. Smith, H. Molina, D. Mao, and D.H. Munn. 2001. Prevention of T cell-driven complement activation and inflammation by tryptophan catabolism during pregnancy. Nat. Immunol. 2:64-68.
    • (2001) Nat. Immunol. , vol.2 , pp. 64-68
    • Mellor, A.L.1    Sivakumar, J.2    Chandler, P.3    Smith, K.4    Molina, H.5    Mao, D.6    Munn, D.H.7
  • 10
    • 0037331182 scopus 로고    scopus 로고
    • At the innate frontiers between mother and fetus: Linking abortion with complement activation
    • Caucheteux, S.M., C. Kanellopoulos-Langevin, and D.M. Ojcius. 2003. At the innate frontiers between mother and fetus: linking abortion with complement activation. Immunity. 18:169-172.
    • (2003) Immunity , vol.18 , pp. 169-172
    • Caucheteux, S.M.1    Kanellopoulos-Langevin, C.2    Ojcius, D.M.3
  • 14
    • 27444433714 scopus 로고    scopus 로고
    • Circulating angiogenic factors in the pathogenesis and prediction of preeclampsia
    • Lam, C., K.H. Lim, and S.A. Karumanchi. 2005. Circulating angiogenic factors in the pathogenesis and prediction of preeclampsia. Hypertension. 46:1077-1085.
    • (2005) Hypertension , vol.46 , pp. 1077-1085
    • Lam, C.1    Lim, K.H.2    Karumanchi, S.A.3
  • 15
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara, N., H.P. Gerber, and J. LeCouter. 2003. The biology of VEGF and its receptors. Nat. Med. 9:669-676.
    • (2003) Nat. Med. , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 16
    • 0027421333 scopus 로고
    • Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor
    • Kendall, R.L., and K.A. Thomas. 1993. Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor. Proc. Natl. Acad. Sci. USA. 90:10705-10709.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10705-10709
    • Kendall, R.L.1    Thomas, K.A.2
  • 17
    • 0033334764 scopus 로고    scopus 로고
    • Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (FLT-1) pre-mRNA is important for the regulation of VEGF activity
    • He, Y., S.K. Smith, K.A. Day, D.E. Clark, D.R. Licence, and D.S. Charnock-Jones. 1999. Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (FLT-1) pre-mRNA is important for the regulation of VEGF activity. Mol. Endocrinol. 13:537-545.
    • (1999) Mol. Endocrinol. , vol.13 , pp. 537-545
    • He, Y.1    Smith, S.K.2    Day, K.A.3    Clark, D.E.4    Licence, D.R.5    Charnock-Jones, D.S.6
  • 18
    • 10344251488 scopus 로고    scopus 로고
    • GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice
    • Eubank, T.D., R. Roberts, M. Galloway, Y. Wang, D.E. Cohn, and C.B. Marsh. 2004. GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice. Immunity. 21:831-842.
    • (2004) Immunity , vol.21 , pp. 831-842
    • Eubank, T.D.1    Roberts, R.2    Galloway, M.3    Wang, Y.4    Cohn, D.E.5    Marsh, C.B.6
  • 19
    • 31944436278 scopus 로고    scopus 로고
    • Soluble vascular endothelial growth factor receptor-1 (sFLT-1) mediates downregulation of FLT-1 and prevents activated neutrophils from women with preeclampsia from additional migration by VEGF
    • Krysiak, O., A. Bretschneider, E. Zhong, J. Webb, H. Hopp, S. Verlohren, N. Fuhr, M. Lanowska, A. Nonnenmacher, R. Vetter, et al. 2005. Soluble vascular endothelial growth factor receptor-1 (sFLT-1) mediates downregulation of FLT-1 and prevents activated neutrophils from women with preeclampsia from additional migration by VEGF. Circ. Res. 97:1253-1261.
    • (2005) Circ. Res. , vol.97 , pp. 1253-1261
    • Krysiak, O.1    Bretschneider, A.2    Zhong, E.3    Webb, J.4    Hopp, H.5    Verlohren, S.6    Fuhr, N.7    Lanowska, M.8    Nonnenmacher, A.9    Vetter, R.10
  • 20
    • 0037373006 scopus 로고    scopus 로고
    • Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia
    • Maynard, S.E., J.Y. Min, J. Merchan, K.H. Lim, J. Li, S. Mondal, T.A. Libermann, J.P. Morgan, F.W. Sellke, I.E. Stillman, et al. 2003. Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J. Clin. Invest. 111:649-658.
    • (2003) J. Clin. Invest. , vol.111 , pp. 649-658
    • Maynard, S.E.1    Min, J.Y.2    Merchan, J.3    Lim, K.H.4    Li, J.5    Mondal, S.6    Libermann, T.A.7    Morgan, J.P.8    Sellke, F.W.9    Stillman, I.E.10
  • 23
    • 0036114404 scopus 로고    scopus 로고
    • Vascular endothelial growth factor ligands and receptors that regulate human cytotrophoblast survival are dysregulated in severe preeclampsia and hemolysis, elevated liver enzymes, and low platelets syndrome
    • Zhou, Y., M. McMaster, K. Woo, M. Janatpour, J. Perry, T. Karpanen, K. Alitalo, C. Damsky, and S.J. Fisher. 2002. Vascular endothelial growth factor ligands and receptors that regulate human cytotrophoblast survival are dysregulated in severe preeclampsia and hemolysis, elevated liver enzymes, and low platelets syndrome. Am. J. Pathol. 160:1405-1423.
    • (2002) Am. J. Pathol. , vol.160 , pp. 1405-1423
    • Zhou, Y.1    McMaster, M.2    Woo, K.3    Janatpour, M.4    Perry, J.5    Karpanen, T.6    Alitalo, K.7    Damsky, C.8    Fisher, S.J.9
  • 24
    • 10744228170 scopus 로고    scopus 로고
    • Blockade of vascular endothelial growth factor receptor I (VEGF-RI), but not VEGF-RII, suppresses joint destruction in the K/BxN model of rheumatoid arthritis
    • De Bandt, M., M.H. Ben Mahdi, V. Ollivier, M. Grossin, M. Dupuis, M. Gaudry, P. Bohlen, K.E. Lipson, A. Rice, Y. Wu, et al. 2003. Blockade of vascular endothelial growth factor receptor I (VEGF-RI), but not VEGF-RII, suppresses joint destruction in the K/BxN model of rheumatoid arthritis. J. Immunol. 171:4853-4859.
    • (2003) J. Immunol. , vol.171 , pp. 4853-4859
    • De Bandt, M.1    Ben Mahdi, M.H.2    Ollivier, V.3    Grossin, M.4    Dupuis, M.5    Gaudry, M.6    Bohlen, P.7    Lipson, K.E.8    Rice, A.9    Wu, Y.10
  • 27
    • 21444452423 scopus 로고    scopus 로고
    • Extra-placental expression of vascular endothelial growth factor receptor-1, (Flt-1) and soluble Flt-1 (sFlt-1), by peripheral blood mononuclear cells (PBMCs) in normotensive and preeclamptic pregnant women
    • Rajakumar, A., H.M. Michael, P.A. Rajakumar, E. Shibata, C.A. Hubel, S.A. Karumanchi, R. Thadhani, M. Wolf, G. Harger, and N. Markovic. 2005. Extra-placental expression of vascular endothelial growth factor receptor-1, (Flt-1) and soluble Flt-1 (sFlt-1), by peripheral blood mononuclear cells (PBMCs) in normotensive and preeclamptic pregnant women. Placenta. 26:563-573.
    • (2005) Placenta , vol.26 , pp. 563-573
    • Rajakumar, A.1    Michael, H.M.2    Rajakumar, P.A.3    Shibata, E.4    Hubel, C.A.5    Karumanchi, S.A.6    Thadhani, R.7    Wolf, M.8    Harger, G.9    Markovic, N.10
  • 28
    • 0031965342 scopus 로고    scopus 로고
    • Cytokine-dependent abortion in CBA x DBA/2 mice is mediated by the procoagulant fgl2 prothrombinase
    • Clark, D.A., G. Chaouat, P.C. Arck, H.W. Mittruecker, and G.A. Levy. 1998. Cytokine-dependent abortion in CBA x DBA/2 mice is mediated by the procoagulant fgl2 prothrombinase. J. Immunol. 160:545-549.
    • (1998) J. Immunol. , vol.160 , pp. 545-549
    • Clark, D.A.1    Chaouat, G.2    Arck, P.C.3    Mittruecker, H.W.4    Levy, G.A.5
  • 29
    • 13544261752 scopus 로고    scopus 로고
    • Intercellular adhesion molecule-1/LFA-1 cross talk is a proximate mediator capable of disrupting immune integration and tolerance mechanism at the feto-maternal interface in murine pregnancies
    • Blois, S., M. Tometten, J. Kandil, E. Hagen, B.F. Klapp, R.A. Margni, and P.C. Arck. 2005. Intercellular adhesion molecule-1/LFA-1 cross talk is a proximate mediator capable of disrupting immune integration and tolerance mechanism at the feto-maternal interface in murine pregnancies. J. Immunol. 174:1820-1829.
    • (2005) J. Immunol. , vol.174 , pp. 1820-1829
    • Blois, S.1    Tometten, M.2    Kandil, J.3    Hagen, E.4    Klapp, B.F.5    Margni, R.A.6    Arck, P.C.7
  • 30
    • 0028954469 scopus 로고
    • Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein
    • Kim, Y.U., T. Kinoshita, H. Molina, D. Hourcade, T. Seya, L.M. Wagner, and V.M. Holers. 1995. Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein. J. Exp. Med. 181:151-159.
    • (1995) J. Exp. Med. , vol.181 , pp. 151-159
    • Kim, Y.U.1    Kinoshita, T.2    Molina, H.3    Hourcade, D.4    Seya, T.5    Wagner, L.M.6    Holers, V.M.7
  • 31
    • 0029114993 scopus 로고
    • Anti-C5 monoclonal antibody therapy prevents collagen-induced arthritis and ameliorates established disease
    • Wang, Y., S.A. Rollins, J.A. Madri, and L.A. Matis. 1995. Anti-C5 monoclonal antibody therapy prevents collagen-induced arthritis and ameliorates established disease. Proc. Natl. Acad. Sci. USA. 92:8955-8959.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8955-8959
    • Wang, Y.1    Rollins, S.A.2    Madri, J.A.3    Matis, L.A.4
  • 32
    • 0034659827 scopus 로고    scopus 로고
    • A new small molecule C5a receptor antagonist inhibits the reverse-passive Arthus reaction and endotoxic shock in rats
    • Strachan, A.J., T.M. Woodruff, G. Haaima, D.P. Fairlie, and S.M. Taylor. 2000. A new small molecule C5a receptor antagonist inhibits the reverse-passive Arthus reaction and endotoxic shock in rats. J. Immunol. 164:6560-6565.
    • (2000) J. Immunol. , vol.164 , pp. 6560-6565
    • Strachan, A.J.1    Woodruff, T.M.2    Haaima, G.3    Fairlie, D.P.4    Taylor, S.M.5
  • 34
    • 0021946245 scopus 로고
    • Factor B, the complement alternative pathway serine proteinase, is a major constitutive protein synthesized and secreted by resident and elicited mouse macrophages
    • Sundsmo, J.S., J.R. Chin, R.A. Papin, D.S. Fair, and Z. Werb. 1985. Factor B, the complement alternative pathway serine proteinase, is a major constitutive protein synthesized and secreted by resident and elicited mouse macrophages. J. Exp. Med. 161:306-322.
    • (1985) J. Exp. Med. , vol.161 , pp. 306-322
    • Sundsmo, J.S.1    Chin, J.R.2    Papin, R.A.3    Fair, D.S.4    Werb, Z.5
  • 37
    • 9144243607 scopus 로고    scopus 로고
    • Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation
    • Girardi, G., P. Redecha, and J.E. Salmon. 2004. Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation. Nat. Med. 10:1222-1226.
    • (2004) Nat. Med. , vol.10 , pp. 1222-1226
    • Girardi, G.1    Redecha, P.2    Salmon, J.E.3
  • 38
    • 0030068055 scopus 로고    scopus 로고
    • Tumor necrosis factors: Pivotal components of pregnancy?
    • Hunt, J.S., H.L. Chen, and L. Miller. 1996. Tumor necrosis factors: pivotal components of pregnancy? Biol. Reprod. 54:554-562.
    • (1996) Biol. Reprod. , vol.54 , pp. 554-562
    • Hunt, J.S.1    Chen, H.L.2    Miller, L.3
  • 39
    • 10844288801 scopus 로고    scopus 로고
    • TNF-alpha is a critical effector and a target for therapy in antiphospholipid antibody-induced pregnancy loss
    • Berman, J., G. Girardi, and J.E. Salmon. 2005. TNF-alpha is a critical effector and a target for therapy in antiphospholipid antibody-induced pregnancy loss. J. Immunol. 174:485-490.
    • (2005) J. Immunol. , vol.174 , pp. 485-490
    • Berman, J.1    Girardi, G.2    Salmon, J.E.3
  • 40
    • 1242271321 scopus 로고    scopus 로고
    • Secretion of tumor necrosis factor-alpha from human placental tissues induced by hypoxia-reoxygenation causes endothelial cell activation in vitro: A potential mediator of the inflammatory response in preeclampsia
    • Hung, T.H., D.S. Charnock-Jones, J.N. Skepper, and G.J. Burton. 2004. Secretion of tumor necrosis factor-alpha from human placental tissues induced by hypoxia-reoxygenation causes endothelial cell activation in vitro: a potential mediator of the inflammatory response in preeclampsia. Am. J. Pathol. 164:1049-1061.
    • (2004) Am. J. Pathol. , vol.164 , pp. 1049-1061
    • Hung, T.H.1    Charnock-Jones, D.S.2    Skepper, J.N.3    Burton, G.J.4
  • 41
    • 0030977208 scopus 로고    scopus 로고
    • Soluble receptors neutralizing TNF-alpha and IL-1 block stress-triggered murine abortion
    • Arck, P.C., A.B. Troutt, and D.A. Clark. 1997. Soluble receptors neutralizing TNF-alpha and IL-1 block stress-triggered murine abortion. Am. J. Reprod. Immunol. 37:262-266.
    • (1997) Am. J. Reprod. Immunol. , vol.37 , pp. 262-266
    • Arck, P.C.1    Troutt, A.B.2    Clark, D.A.3
  • 42
    • 0033853079 scopus 로고    scopus 로고
    • TNF-alpha/TNFRI in primary and immortalized first trimester cytotrophoblasts
    • Knofler, M., B. Mosl, S. Bauer, G. Griesinger, and P. Husslein. 2000. TNF-alpha/TNFRI in primary and immortalized first trimester cytotrophoblasts. Placenta. 21:525-535.
    • (2000) Placenta , vol.21 , pp. 525-535
    • Knofler, M.1    Mosl, B.2    Bauer, S.3    Griesinger, G.4    Husslein, P.5
  • 43
    • 0032476725 scopus 로고    scopus 로고
    • Requirement of the mouse I-mfa gene for placental development and skeletal patterning
    • Kraut, N., L. Snider, C.M. Chen, S.J. Tapscott, and M. Groudine. 1998. Requirement of the mouse I-mfa gene for placental development and skeletal patterning. EMBO J. 17:6276-6288.
    • (1998) EMBO J. , vol.17 , pp. 6276-6288
    • Kraut, N.1    Snider, L.2    Chen, C.M.3    Tapscott, S.J.4    Groudine, M.5
  • 44
    • 17044371242 scopus 로고    scopus 로고
    • How to make a placenta: Mechanisms of trophoblast cell differentiation in mice - A review
    • Cross, J.C. 2005. How to make a placenta: mechanisms of trophoblast cell differentiation in mice - a review. Placenta. 26:S3-S9.
    • (2005) Placenta , vol.26
    • Cross, J.C.1
  • 45
    • 0030017083 scopus 로고    scopus 로고
    • Downregulation of vascular endothelial growth factor receptors by tumor necrosis factor-alpha in cultured human vascular endothelial cells
    • Patterson, C., M.A. Perrella, W.O. Endege, M. Yoshizumi, M.E. Lee, and E. Haber. 1996. Downregulation of vascular endothelial growth factor receptors by tumor necrosis factor-alpha in cultured human vascular endothelial cells. J. Clin. Invest. 98:490-496.
    • (1996) J. Clin. Invest. , vol.98 , pp. 490-496
    • Patterson, C.1    Perrella, M.A.2    Endege, W.O.3    Yoshizumi, M.4    Lee, M.E.5    Haber, E.6
  • 46
    • 0031975690 scopus 로고    scopus 로고
    • The role of placental trophoblast in the pathophysiology of the antiphospholipid antibody syndrome
    • Rote, N.S., E. Vogt, G. DeVere, A.R. Obringer, and A.K. Ng. 1998. The role of placental trophoblast in the pathophysiology of the antiphospholipid antibody syndrome. Am. J. Reprod. Immunol. 39:125-136.
    • (1998) Am. J. Reprod. Immunol. , vol.39 , pp. 125-136
    • Rote, N.S.1    Vogt, E.2    DeVere, G.3    Obringer, A.R.4    Ng, A.K.5
  • 47
    • 0026782588 scopus 로고
    • Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy
    • Rodesch, F., P. Simon, C. Donner, and E. Jauniaux. 1992. Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy. Obstet. Gynecol. 80:283-285.
    • (1992) Obstet. Gynecol. , vol.80 , pp. 283-285
    • Rodesch, F.1    Simon, P.2    Donner, C.3    Jauniaux, E.4
  • 49
    • 1642463804 scopus 로고    scopus 로고
    • The lectin-complement pathway - Its role in innate immunity and evolution
    • Fujita, T., M. Matsushita, and Y. Endo. 2004. The lectin-complement pathway - its role in innate immunity and evolution. Immunol. Rev. 198:185-202.
    • (2004) Immunol. Rev. , vol.198 , pp. 185-202
    • Fujita, T.1    Matsushita, M.2    Endo, Y.3
  • 50
    • 0035908925 scopus 로고    scopus 로고
    • Inhibition of mannose-binding lectin reduces postischemic myocardial reperfusion injury
    • Jordan, J.E., M.C. Montalto, and G.L. Stahl. 2001. Inhibition of mannose-binding lectin reduces postischemic myocardial reperfusion injury. Circulation. 104:1413-1418.
    • (2001) Circulation , vol.104 , pp. 1413-1418
    • Jordan, J.E.1    Montalto, M.C.2    Stahl, G.L.3
  • 51
    • 0347480217 scopus 로고    scopus 로고
    • Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway
    • Mao, D., X. Wu, C. Deppong, L.D. Friend, G. Dolecki, D.M. Nelson, and H. Molina. 2003. Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway. Immunity. 19:813-822.
    • (2003) Immunity , vol.19 , pp. 813-822
    • Mao, D.1    Wu, X.2    Deppong, C.3    Friend, L.D.4    Dolecki, G.5    Nelson, D.M.6    Molina, H.7
  • 52
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • Gordon, S. 2003. Alternative activation of macrophages. Nat. Rev. Immunol. 3:23-35.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 23-35
    • Gordon, S.1
  • 53
    • 0028042424 scopus 로고
    • FcR gamma chain deletion results in pleiotrophic effector cell defects
    • Takai, T., M. Li, D. Sylvestre, R. Clynes, and J.V. Ravetch. 1994. FcR gamma chain deletion results in pleiotrophic effector cell defects. Cell. 76:519-529.
    • (1994) Cell , vol.76 , pp. 519-529
    • Takai, T.1    Li, M.2    Sylvestre, D.3    Clynes, R.4    Ravetch, J.V.5
  • 54
    • 0029795542 scopus 로고    scopus 로고
    • The C5a chemoattractant receptor mediates mucosal defence to infection
    • Hopken, U.E., B. Lu, N.P. Gerard, and C. Gerard. 1996. The C5a chemoattractant receptor mediates mucosal defence to infection. Nature. 383:86-89.
    • (1996) Nature , vol.383 , pp. 86-89
    • Hopken, U.E.1    Lu, B.2    Gerard, N.P.3    Gerard, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.