-
1
-
-
0033011755
-
Molecular pathogenesis of chronic lymphocytic leukemia: Factors and signaling pathways regulating cell growth and survival
-
Meinhardt, G.; Wendtner, C. M.; Hallek, M. Molecular pathogenesis of chronic lymphocytic leukemia: factors and signaling pathways regulating cell growth and survival. J. Mol. Med. 1999, 77, 282-293.
-
(1999)
J. Mol. Med
, vol.77
, pp. 282-293
-
-
Meinhardt, G.1
Wendtner, C.M.2
Hallek, M.3
-
2
-
-
0026015638
-
Fludarabine - a new agent with marked cytoreductive activity in untreated chronic lymphocytic-leukemia
-
Keating, M. J.; Kantarjian, H.; OBrien, S.; Koller, C.; Talpaz, M.; Schachner, J.; Childs, C. C.; Freireich, E. J.; Mccredie, K. B. Fludarabine - a new agent with marked cytoreductive activity in untreated chronic lymphocytic-leukemia. J. Clin. Oncol. 1991, 9, 44-49.
-
(1991)
J. Clin. Oncol
, vol.9
, pp. 44-49
-
-
Keating, M.J.1
Kantarjian, H.2
Obrien, S.3
Koller, C.4
Talpaz, M.5
Schachner, J.6
Childs, C.C.7
Freireich, E.J.8
McCredie, K.B.9
-
3
-
-
0034649696
-
Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia
-
Rai, K. R.; Peterson, B. L.; Appelbaum, F. R.; Kolitz, J.; Elias, L.; Shepherd, L.; Hines, J.; Threatte, G. A.; Larson, R. A.; Cheson, B. D.; Schiffer, C. A. Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia. N. Engl. J. Med. 2000, 343, 1750-1757.
-
(2000)
N. Engl. J. Med
, vol.343
, pp. 1750-1757
-
-
Rai, K.R.1
Peterson, B.L.2
Appelbaum, F.R.3
Kolitz, J.4
Elias, L.5
Shepherd, L.6
Hines, J.7
Threatte, G.A.8
Larson, R.A.9
Cheson, B.D.10
Schiffer, C.A.11
-
4
-
-
10544231614
-
Phase I/II evaluation of 2' deoxycoformycin (Pentostatin) in a five-day schedule for the treatment of relapse/refractory chronic lymphocytic leukaemia (CLL)
-
Johnson, S.; Catovsky, D.; Child, J.; Newland, A. C.; Milligan, D.; Janmohamed, R. Phase I/II evaluation of 2' deoxycoformycin (Pentostatin) in a five-day schedule for the treatment of relapse/refractory chronic lymphocytic leukaemia (CLL). Blood 1996,88, 2350-2350.
-
(1996)
Blood
, vol.88
, pp. 2350-2350
-
-
Johnson, S.1
Catovsky, D.2
Child, J.3
Newland, A.C.4
Milligan, D.5
Janmohamed, R.6
-
5
-
-
0032529509
-
Long-term follow-up of patients with chronic lymphocytic leukemia (CLL) receiving fludarabine regimens as initial therapy
-
Keating, M. J.; O'Brien, S.; Lerner, S.; Koller, C.; Beran, M.; Robertson, L. E.; Freireich, E. J.; Estey, E.; Kantarjian, H. Long-term follow-up of patients with chronic lymphocytic leukemia (CLL) receiving fludarabine regimens as initial therapy. Blood 1998, 92, 1165-1171.
-
(1998)
Blood
, vol.92
, pp. 1165-1171
-
-
Keating, M.J.1
O'Brien, S.2
Lerner, S.3
Koller, C.4
Beran, M.5
Robertson, L.E.6
Freireich, E.J.7
Estey, E.8
Kantarjian, H.9
-
6
-
-
0035889147
-
Randomized comparison of fludarabine, CAP, and ChOP in 938 previously untreated stage B and C chronic lymphocytic leukemia patients
-
Leporrier, M.; Chevret, S.; Cazin, B.; Boudjerra, N.; Feugier, P.; Desablens, B.; Rapp, M. J.; Jaubert, J.; Autrand, C.; Divine, M.; Dreyfus, B.; Maloum, K.; Travade, P.; Dighiero, G.; Binet, J. L.; Chastang, C. Randomized comparison of fludarabine, CAP, and ChOP in 938 previously untreated stage B and C chronic lymphocytic leukemia patients. Blood 2001, 98, 2319-2325.
-
(2001)
Blood
, vol.98
, pp. 2319-2325
-
-
Leporrier, M.1
Chevret, S.2
Cazin, B.3
Boudjerra, N.4
Feugier, P.5
Desablens, B.6
Rapp, M.J.7
Jaubert, J.8
Autrand, C.9
Divine, M.10
Dreyfus, B.11
Maloum, K.12
Travade, P.13
Dighiero, G.14
Binet, J.L.15
Chastang, C.16
-
7
-
-
0034893776
-
Fludarabine plus cyclophosphamide is an efficient treatment for advanced chronic lymphocytic leukaemia, (CLL): Results of a phase II study of the German CLL Study Group
-
Hallek, M.; Schmitt, B.; Wilhelm, M.; Busch, R.; Krober, A.; Fostitsch, H. P.; Sezer, O.; Herold, M.; Knauf, W.; Wendtner, C. M.; Kuse, R.; Freund, M.; Franke, A.; Schriever, F.; Nerl, C.; Dohner, H.; Thiel, E.; Hiddemann, W.; Brittinger, G.; Emmerich, B. Fludarabine plus cyclophosphamide is an efficient treatment for advanced chronic lymphocytic leukaemia, (CLL): results of a phase II study of the German CLL Study Group. Br. J. Haematol. 2001, 114, 342-348.
-
(2001)
Br. J. Haematol
, vol.114
, pp. 342-348
-
-
Hallek, M.1
Schmitt, B.2
Wilhelm, M.3
Busch, R.4
Krober, A.5
Fostitsch, H.P.6
Sezer, O.7
Herold, M.8
Knauf, W.9
Wendtner, C.M.10
Kuse, R.11
Freund, M.12
Franke, A.13
Schriever, F.14
Nerl, C.15
Dohner, H.16
Thiel, E.17
Hiddemann, W.18
Brittinger, G.19
Emmerich, B.20
more..
-
8
-
-
34547880421
-
Revision of the guidelines for diagnosis and therapy of chronic lymphocytic leukemia (CLL). Best Pract. Res. Clin
-
Eichhorst, B.; Hallek, M. Revision of the guidelines for diagnosis and therapy of chronic lymphocytic leukemia (CLL). Best Pract. Res. Clin. Haematol. 2007, 20, 469-477.
-
(2007)
Haematol
, vol.20
, pp. 469-477
-
-
Eichhorst, B.1
Hallek, M.2
-
9
-
-
0036125593
-
The role of nucleoside analogues in the treatment of chronic lymphocytic leukemia-lessons learned from prospective randomized trials
-
Robak, T. The role of nucleoside analogues in the treatment of chronic lymphocytic leukemia-lessons learned from prospective randomized trials. Leuk. Lymphoma 2002, 43, 537-548.
-
(2002)
Leuk. Lymphoma
, vol.43
, pp. 537-548
-
-
Robak, T.1
-
10
-
-
0037214931
-
Phase II study of cladribine and cyclophosphamide in patients with chronic lymphocytic leukemia and prolymphocytic leukemia
-
Montillo, M.; Tedeschi, A.; O'Brien, S.; Di Raimondo, F.; Lerner, S.; Ferrajoli, A.; Morra, E.; Keating, M. J. Phase II study of cladribine and cyclophosphamide in patients with chronic lymphocytic leukemia and prolymphocytic leukemia. Cancer 2003, 97, 114-120.
-
(2003)
Cancer
, vol.97
, pp. 114-120
-
-
Montillo, M.1
Tedeschi, A.2
O'Brien, S.3
Di Raimondo, F.4
Lerner, S.5
Ferrajoli, A.6
Morra, E.7
Keating, M.J.8
-
11
-
-
37549046061
-
Consolidation and maintenance immunotherapy with rituximab improve clinical outcome in patients with B-cell chronic lymphocytic leukemia
-
Del Poeta, G.; Del Principe, M. I.; Buccisano, F.; Maurillo, L.; Capelli, G.; Luciano, F.; Perrotti, A. P.; Degan, M.; Venditti, A.; de Fabritiis, P.; Gattei, V.; Amadori, S. Consolidation and maintenance immunotherapy with rituximab improve clinical outcome in patients with B-cell chronic lymphocytic leukemia. Cancer 2008, 112, 119-128.
-
(2008)
Cancer
, vol.112
, pp. 119-128
-
-
Del Poeta, G.1
Del Principe, M.I.2
Buccisano, F.3
Maurillo, L.4
Capelli, G.5
Luciano, F.6
Perrotti, A.P.7
Degan, M.8
Venditti, A.9
de Fabritiis, P.10
Gattei, V.11
Amadori, S.12
-
12
-
-
33749600951
-
Rituximab combined with cladribine or with cladribine and cyclophosphamide in heavily pretreated patients with indolent lymphoproliferative disorders and mantle cell lymphoma
-
Robak, T.; Smolewski, P.; Cebula, B.; Szmigielska-Kaplon, A.; Chojnowski, K.; Blonski, J. Z. Rituximab combined with cladribine or with cladribine and cyclophosphamide in heavily pretreated patients with indolent lymphoproliferative disorders and mantle cell lymphoma. Cancer 2006, 107, 1542-1550.
-
(2006)
Cancer
, vol.107
, pp. 1542-1550
-
-
Robak, T.1
Smolewski, P.2
Cebula, B.3
Szmigielska-Kaplon, A.4
Chojnowski, K.5
Blonski, J.Z.6
-
13
-
-
34547961559
-
Chemoimmunotherapy of chronic lymphocytic leukemia
-
Tam, C. S.; Keating, M. J. Chemoimmunotherapy of chronic lymphocytic leukemia. Best Pract. Res. Clin. Haematol. 2007, 20, 479-498.
-
(2007)
Best Pract. Res. Clin. Haematol
, vol.20
, pp. 479-498
-
-
Tam, C.S.1
Keating, M.J.2
-
14
-
-
0036738061
-
Rituximab reduces the number of peripheral blood B-cells in vitro mainly by effector cell-mediated mechanisms
-
Voso, M. T.; Pantel, G.; Rutella, S.; Weis, M.; D'Alo, F.; Urbano, R.; Leone, G.; Haas, R.; Hohaus, S. Rituximab reduces the number of peripheral blood B-cells in vitro mainly by effector cell-mediated mechanisms. Haematologica 2002, 87, 918-925.
-
(2002)
Haematologica
, vol.87
, pp. 918-925
-
-
Voso, M.T.1
Pantel, G.2
Rutella, S.3
Weis, M.4
D'Alo, F.5
Urbano, R.6
Leone, G.7
Haas, R.8
Hohaus, S.9
-
15
-
-
0035871445
-
Rituximab using a thrice weekly dosing schedule in B-Cell chronic lymphocytic leukemia and small lymphocytic lymphoma demonstrates clinical activity and acceptable toxicity
-
Byrd, J. C.; Murphy, T.; Howard, R. S.; Lucas, M. S.; Goodrich, A.; Park, K.; Pearson, M.; Waselenko, J. K.; Ling, G.; Grever, M. R.; Grillo-Lopez, A. J.; Rosenberg, J.; Kunkel, L.; Flinn, I. W. Rituximab using a thrice weekly dosing schedule in B-Cell chronic lymphocytic leukemia and small lymphocytic lymphoma demonstrates clinical activity and acceptable toxicity. J. Clin. Oncol. 2001,19, 2153-2164.
-
(2001)
J. Clin. Oncol
, vol.19
, pp. 2153-2164
-
-
Byrd, J.C.1
Murphy, T.2
Howard, R.S.3
Lucas, M.S.4
Goodrich, A.5
Park, K.6
Pearson, M.7
Waselenko, J.K.8
Ling, G.9
Grever, M.R.10
Grillo-Lopez, A.J.11
Rosenberg, J.12
Kunkel, L.13
Flinn, I.W.14
-
16
-
-
0036757311
-
Standard-dose anti-CD20 antibody rituximab has efficacy in chronic lymphocytic leukaemia: Results from a Nordic multicentre study
-
Itala, M.; Geisler, C. H.; Kimby, E.; Juvonen, E.; Tjonnfjord, G.; Karlsson, K.; Remes, K. Standard-dose anti-CD20 antibody rituximab has efficacy in chronic lymphocytic leukaemia: results from a Nordic multicentre study. Eur. J. Haematol. 2002, 69, 129-134.
-
(2002)
Eur. J. Haematol
, vol.69
, pp. 129-134
-
-
Itala, M.1
Geisler, C.H.2
Kimby, E.3
Juvonen, E.4
Tjonnfjord, G.5
Karlsson, K.6
Remes, K.7
-
17
-
-
0035871441
-
Rituximab dose-escalation trial in chronic lymphocytic leukemia
-
O'Brien, S. M.; Kantarjian, H.; Thomas, D. A.; Giles, F. J.; Freireich, E. J.; Cortes, J.; Lerner, S.; Keating, M. J. Rituximab dose-escalation trial in chronic lymphocytic leukemia. J. Clin. Oncol. 2001, 19, 2165-2170.
-
(2001)
J. Clin. Oncol
, vol.19
, pp. 2165-2170
-
-
O'Brien, S.M.1
Kantarjian, H.2
Thomas, D.A.3
Giles, F.J.4
Freireich, E.J.5
Cortes, J.6
Lerner, S.7
Keating, M.J.8
-
18
-
-
78649297898
-
Response: Rituximab and fludarabine combination therapy for CLL: Potential future directions of clinical investigation
-
Byrd, J. C.; Rai, K.; Larson, R. A. Response: Rituximab and fludarabine combination therapy for CLL: potential future directions of clinical investigation. Blood 2003, 102, 2309-2310.
-
(2003)
Blood
, vol.102
, pp. 2309-2310
-
-
Byrd, J.C.1
Rai, K.2
Larson, R.A.3
-
19
-
-
0036839469
-
Phase 2 study of a combined immunochemotherapy using rituximab and fludarabine in patients with chronic lymphocytic leukemia
-
Schulz, H.; Klein, S. K.; Rehwald, U.; Reiser, M.; Hinke, A.; Knauf, W. U.; Aulitzky, W. E.; Hensel, M.; Herold, M.; Huhn, D.; Hallek, M.; Diehl, V.; Engert, A. Phase 2 study of a combined immunochemotherapy using rituximab and fludarabine in patients with chronic lymphocytic leukemia. Blood 2002, 100, 3115-3120.
-
(2002)
Blood
, vol.100
, pp. 3115-3120
-
-
Schulz, H.1
Klein, S.K.2
Rehwald, U.3
Reiser, M.4
Hinke, A.5
Knauf, W.U.6
Aulitzky, W.E.7
Hensel, M.8
Herold, M.9
Huhn, D.10
Hallek, M.11
Diehl, V.12
Engert, A.13
-
20
-
-
14344252714
-
Chemoimmunotherapy with fludarabine (F), cyclophosphamide (C), and ritux-imab (R) improves complete response (CR), remission duration and survival as initial therapy of chronic lymphocytic leukemia (CLL)
-
Keating, M. J.; O'Brien, S.; Lerner, S.; Wierda, W.; Kantarjian, H. Chemoimmunotherapy with fludarabine (F), cyclophosphamide (C), and ritux-imab (R) improves complete response (CR), remission duration and survival as initial therapy of chronic lymphocytic leukemia (CLL). J. Clin. Oncol. 2004, 22, 573S-573S.
-
(2004)
J. Clin. Oncol
, vol.22
-
-
Keating, M.J.1
O'Brien, S.2
Lerner, S.3
Wierda, W.4
Kantarjian, H.5
-
21
-
-
23044501404
-
Chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab for relapsed and refractory chronic lymphocytic leukemia
-
Wierda, W.; O'Brien, S.; Wen, S.; Faderl, S.; Garcia-Manero, G.; Thomas, D.; Do, K. A.; Cortes, J.; Koller, C.; Beran, M.; Ferrajoli, A.; Giles, F.; Lerner, S.; Albitar, M.; Kantarjian, H.; Keating, M. Chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab for relapsed and refractory chronic lymphocytic leukemia. J. Clin. Oncol. 2005, 23, 4070-4078.
-
(2005)
J. Clin. Oncol
, vol.23
, pp. 4070-4078
-
-
Wierda, W.1
O'Brien, S.2
Wen, S.3
Faderl, S.4
Garcia-Manero, G.5
Thomas, D.6
Do, K.A.7
Cortes, J.8
Koller, C.9
Beran, M.10
Ferrajoli, A.11
Giles, F.12
Lerner, S.13
Albitar, M.14
Kantarjian, H.15
Keating, M.16
-
22
-
-
0036335916
-
Results of first salvage therapy for patients refractory to a fluidarabine regimen in chronic lymphocytic leukemia
-
Keating, M. J.; O'Brien, S.; Kontoyiannis, D.; Plunkett, W.; Koller, C.; Beran, A.; Lerner, S.; Kantarjian, H. Results of first salvage therapy for patients refractory to a fluidarabine regimen in chronic lymphocytic leukemia. Leuk. Lymphoma 2002, 43, 1755-1762.
-
(2002)
Leuk. Lymphoma
, vol.43
, pp. 1755-1762
-
-
Keating, M.J.1
O'Brien, S.2
Kontoyiannis, D.3
Plunkett, W.4
Koller, C.5
Beran, A.6
Lerner, S.7
Kantarjian, H.8
-
23
-
-
0036273648
-
Clinical effects of alemtuzumab (Campath-1H) in B-cell chronic lymphocytic leukemia
-
Osterborg, A.; Mellstedt, H.; Keating, M. Clinical effects of alemtuzumab (Campath-1H) in B-cell chronic lymphocytic leukemia. Med. Oncol. 2002, 19, S21-S26.
-
(2002)
Med. Oncol
, vol.19
-
-
Osterborg, A.1
Mellstedt, H.2
Keating, M.3
-
24
-
-
0037106502
-
Alemtuzumab in previously treated chronic lymphocytic leukemia patients who also had received fludarabine
-
Rai, K. R.; Freter, C. E.; Mercier, R. J.; Cooper, M. R.; Mitchell, B. S.; Stadtmauer, E. A.; Santabarbara, P.; Wacker, B.; Brettman, L. Alemtuzumab in previously treated chronic lymphocytic leukemia patients who also had received fludarabine. J. Clin. Oncol. 2002, 20, 3891-3897.
-
(2002)
J. Clin. Oncol
, vol.20
, pp. 3891-3897
-
-
Rai, K.R.1
Freter, C.E.2
Mercier, R.J.3
Cooper, M.R.4
Mitchell, B.S.5
Stadtmauer, E.A.6
Santabarbara, P.7
Wacker, B.8
Brettman, L.9
-
25
-
-
11144357657
-
Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions
-
Lozanski, G.; Heerema, N. A.; Flinn, I. W.; Smith, L.; Harbison, J.; Webb, J.; Moran, M.; Lucas, M.; Lin, T.; Hackbarth, M. L.; Proffitt, J. H.; Lucas, D.; Grever, M. R.; Byrd, J. C. Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions. Blood 2004, 103, 3278-3281.
-
(2004)
Blood
, vol.103
, pp. 3278-3281
-
-
Lozanski, G.1
Heerema, N.A.2
Flinn, I.W.3
Smith, L.4
Harbison, J.5
Webb, J.6
Moran, M.7
Lucas, M.8
Lin, T.9
Hackbarth, M.L.10
Proffitt, J.H.11
Lucas, D.12
Grever, M.R.13
Byrd, J.C.14
-
26
-
-
0009351039
-
Campath-1H in refractory B-CLL - Complete remission despite p53 gene mutation
-
Stilgenbauer, S.; Scherer, K.; Krober, A.; Bullinger, L.; Hochsmann, B.; Mayer-Steinacker, R.; Bunjes, D.; Dohner, H. Campath-1H in refractory B-CLL - Complete remission despite p53 gene mutation. Blood 2001, 98, 771A-771A.
-
(2001)
Blood
, vol.98
-
-
Stilgenbauer, S.1
Scherer, K.2
Krober, A.3
Bullinger, L.4
Hochsmann, B.5
Mayer-Steinacker, R.6
Bunjes, D.7
Dohner, H.8
-
27
-
-
33845543049
-
Indications for allogeneic stem cell transplantation in chronic lymphocytic leukemia: The EBMT transplant consensus
-
Dreger, P.; Corradini, P.; Kimby, E.; Michallet, M.; Milligan, D.; Schetelig, J.; Wiktor-Jedrzejczak, W.; Niederwieser, D.; Hallek, M.; Montserrat, E. Indications for allogeneic stem cell transplantation in chronic lymphocytic leukemia: the EBMT transplant consensus. Leukemia 2007, 21, 12-17.
-
(2007)
Leukemia
, vol.21
, pp. 12-17
-
-
Dreger, P.1
Corradini, P.2
Kimby, E.3
Michallet, M.4
Milligan, D.5
Schetelig, J.6
Wiktor-Jedrzejczak, W.7
Niederwieser, D.8
Hallek, M.9
Montserrat, E.10
-
28
-
-
4444227593
-
Stem cell transplantation for chronic lymphocytic leukemia: Should not more patients get a transplant?
-
Jabbour, E.; Keating, M. J.; Champlin, R. E.; Khouri, I. F. Stem cell transplantation for chronic lymphocytic leukemia: should not more patients get a transplant? Bone Marrow Transplant. 2004, 34, 289-297.
-
(2004)
Bone Marrow Transplant
, vol.34
, pp. 289-297
-
-
Jabbour, E.1
Keating, M.J.2
Champlin, R.E.3
Khouri, I.F.4
-
29
-
-
32944475363
-
Phase I to II multicenter study of oblimersen sodium, a Bcl-2 antisense oligonucleotide, in patients with advanced chronic lymphocytic leukemia
-
O'Brien, S. M.; Cunningham, C. C.; Golenkov, A. K.; Turkina, A. G.; Novick, S. C.; Rai, K. R. Phase I to II multicenter study of oblimersen sodium, a Bcl-2 antisense oligonucleotide, in patients with advanced chronic lymphocytic leukemia. J. Clin. Oncol. 2005, 23, 7697-7702.
-
(2005)
J. Clin. Oncol
, vol.23
, pp. 7697-7702
-
-
O'Brien, S.M.1
Cunningham, C.C.2
Golenkov, A.K.3
Turkina, A.G.4
Novick, S.C.5
Rai K., R.6
-
30
-
-
34047217206
-
Randomized phase III trial of fludarabine plus cyclophosphamide with or without oblimersen sodium (Bcl-2 antisense) in patients with relapsed or refractory chronic lymphocytic leukemia
-
O'Brien, S.; Moore, J. O.; Boyd, T. E.; Larratt, L. M.; Skotnicki, A.; Koziner, B.; Chanan-Khan, A. A.; Seymour, J. F.; Bociek, R. G.; Pavletic, S.; Rai, K. R. Randomized phase III trial of fludarabine plus cyclophosphamide with or without oblimersen sodium (Bcl-2 antisense) in patients with relapsed or refractory chronic lymphocytic leukemia. J. Clin. Oncol. 2007, 25, 1114-1120.
-
(2007)
J. Clin. Oncol
, vol.25
, pp. 1114-1120
-
-
O'Brien, S.1
Moore, J.O.2
Boyd, T.E.3
Larratt, L.M.4
Skotnicki, A.5
Koziner, B.6
Chanan-Khan, A.A.7
Seymour, J.F.8
Bociek, R.G.9
Pavletic, S.10
Rai, K.R.11
-
31
-
-
58349116485
-
A phase 1 study evaluating the safety, PK & efficacy of ABT-263 in subjects with refractory or relapsed lymphoid malignancies
-
O'Connor, O.; Czuczman, M. S.; LaCasce, A.; Gerecitano, J.; Leonard, J. P.; Dunleavy, K.; Krivoshik, A.; Shovlin, M.; Narwal, A.; Xiong, H.; Chiu, Y.; Wilson, W. A phase 1 study evaluating the safety, PK & efficacy of ABT-263 in subjects with refractory or relapsed lymphoid malignancies. Ann. Oncol. 2008, 19, 115-116.
-
(2008)
Ann. Oncol
, vol.19
, pp. 115-116
-
-
O'Connor, O.1
Czuczman, M.S.2
Lacasce, A.3
Gerecitano, J.4
Leonard, J.P.5
Dunleavy, K.6
Krivoshik, A.7
Shovlin, M.8
Narwal, A.9
Xiong, H.10
Chiu, Y.11
Wilson, W.12
-
32
-
-
0034214847
-
The Wnt/Ca2+ pathway - a new vertebrate Wnt signaling pathway takes shape
-
Kuhl, M.; Sheldahl, L. C.; Park, M.; Miller, J. R.; Moon, R. T. The Wnt/Ca2+ pathway - a new vertebrate Wnt signaling pathway takes shape. Trends Genet. 2000, 16, 279-283.
-
(2000)
Trends Genet
, vol.16
, pp. 279-283
-
-
Kuhl, M.1
Sheldahl, L.C.2
Park, M.3
Miller, J.R.4
Moon, R.T.5
-
33
-
-
0038581580
-
Wnt signaling, Ca2+, and cyclic GMP: Visualizing frizzled functions
-
Wang, H. Y.; Malbon, C. C. Wnt signaling, Ca2+, and cyclic GMP: Visualizing frizzled functions. Science 2003, 300, 1529-1530.
-
(2003)
Science
, vol.300
, pp. 1529-1530
-
-
Wang, H.Y.1
Malbon, C.C.2
-
34
-
-
0033828645
-
Jun mediates Frizzled-induced R3/R4 cell fate distinction and planar polarity determination in the Drosophila eye
-
Weber, U.; Paricio, N.; Mlodzik, M. Jun mediates Frizzled-induced R3/R4 cell fate distinction and planar polarity determination in the Drosophila eye. Development 2000, 127, 3619-3629.
-
(2000)
Development
, vol.127
, pp. 3619-3629
-
-
Weber, U.1
Paricio, N.2
Mlodzik, M.3
-
35
-
-
0036418966
-
A three-tiered mechanism for regulation of planar cell polarity
-
Tree, D. R. P.; Ma, D. L.; Axelrod, J. D. A three-tiered mechanism for regulation of planar cell polarity. Semin. Cell Dev. Biol. 2002, 13, 217-224.
-
(2002)
Semin. Cell Dev. Biol
, vol.13
, pp. 217-224
-
-
Tree, D.R.P.1
Ma, D.L.2
Axelrod, J.D.3
-
36
-
-
0031080919
-
Modulation of embryonic intracellular Ca2+ signaling by Wnt-5A
-
Slusarski, D. C.; YangSnyder, J.; Busa, W. B.; Moon, R. T. Modulation of embryonic intracellular Ca2+ signaling by Wnt-5A. Dev. Biol. 1997, 182, 114-120.
-
(1997)
Dev. Biol
, vol.182
, pp. 114-120
-
-
Slusarski, D.C.1
Yangsnyder, J.2
Busa, W.B.3
Moon, R.T.4
-
37
-
-
2242453282
-
Signaling of rat Frizzled-2 through phosphodiesterase and cyclic GMP
-
Ahumada, A.; Slusarski, D. C.; Liu, X. X.; Moon, R. T.; Malbon, C. C.; Wang, H. Y. Signaling of rat Frizzled-2 through phosphodiesterase and cyclic GMP. Science 2002, 298, 2006-2010.
-
(2002)
Science
, vol.298
, pp. 2006-2010
-
-
Ahumada, A.1
Slusarski, D.C.2
Liu, X.X.3
Moon, R.T.4
Malbon, C.C.5
Wang, H.Y.6
-
38
-
-
0031883962
-
Redundant regulation of T cell differentiation and TCR alpha gene expression by the transcription factors LEF-1 and TCF-1
-
Okamura, R. M.; Sigvardsson, M.; Galceran, J.; Verbeek, S.; Clevers, H.; Grosschedl, R. Redundant regulation of T cell differentiation and TCR alpha gene expression by the transcription factors LEF-1 and TCF-1. Immunity 1998, 8, 11-20.
-
(1998)
Immunity
, vol.8
, pp. 11-20
-
-
Okamura, R.M.1
Sigvardsson, M.2
Galceran, J.3
Verbeek, S.4
Clevers, H.5
Grosschedl, R.6
-
39
-
-
0033711624
-
Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism
-
Reya, T.; O'Riordan, M.; Okamura, R.; Devaney, E.; Willert, K.; Nusse, R.; Grosschedl, R. Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism. Immunity 2000,13, 15-24.
-
(2000)
Immunity
, vol.13
, pp. 15-24
-
-
Reya, T.1
O'Riordan, M.2
Okamura, R.3
Devaney, E.4
Willert, K.5
Nusse, R.6
Grosschedl, R.7
-
40
-
-
0037737728
-
A role for Wnt signalling in self-renewal of haematopoietic stem cells
-
Reya, T.; Duncan, A. W.; Ailles, L.; Domen, J.; Scherer, D. C.; Willert, K.; Hintz, L.; Nusse, R.; Weissman, I. L. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature 2003,423, 409-414.
-
(2003)
Nature
, vol.423
, pp. 409-414
-
-
Reya, T.1
Duncan, A.W.2
Ailles, L.3
Domen, J.4
Scherer, D.C.5
Willert, K.6
Hintz, L.7
Nusse, R.8
Weissman, I.L.9
-
41
-
-
33845351956
-
Xu, W. beta-Catenin destruction complex: Insights and questions from a structural perspective
-
Kimelman, D.; Xu, W. beta-Catenin destruction complex: insights and questions from a structural perspective. Oncogene 2006, 25, 7482-7491.
-
(2006)
Oncogene
, vol.25
, pp. 7482-7491
-
-
Kimelman, D.1
-
42
-
-
0032473355
-
Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3 beta and beta-catenin and promotes GSK-3 beta-dependent phosphorylation of beta-catenin
-
Ikeda, S.; Kishida, S.; Yamamoto, H.; Murai, H.; Koyama, S.; Kikuchi, A. Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3 beta and beta-catenin and promotes GSK-3 beta-dependent phosphorylation of beta-catenin. EMBO J. 1998, 17, 1371-1384.
-
(1998)
EMBO J
, vol.17
, pp. 1371-1384
-
-
Ikeda, S.1
Kishida, S.2
Yamamoto, H.3
Murai, H.4
Koyama, S.5
Kikuchi, A.6
-
43
-
-
0032576777
-
Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb
-
Jiang, J.; Struhl, G. Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb. Nature 1998, 391, 493-496.
-
(1998)
Nature
, vol.391
, pp. 493-496
-
-
Jiang, J.1
Struhl, G.2
-
44
-
-
0032170327
-
beta-TrCP is a negative regulator of the Wnt/beta-catenin signaling pathway and dorsal axis formation in Xenopus embryos
-
Marikawa, Y.; Elinson, R. P. beta-TrCP is a negative regulator of the Wnt/beta-catenin signaling pathway and dorsal axis formation in Xenopus embryos. Mech. Dev. 1998, 77, 75-80.
-
(1998)
Mech. Dev
, vol.77
, pp. 75-80
-
-
Marikawa, Y.1
Elinson, R.P.2
-
45
-
-
0028176875
-
Dishevelled and Armadillo Act in the Wingless Signaling Pathway in Drosophila
-
Noordermeer, J.; Klingensmith, J.; Perrimon, N.; Nusse, R. Dishevelled and Armadillo Act in the Wingless Signaling Pathway in Drosophila. Nature 1994, 367, 80-83.
-
(1994)
Nature
, vol.367
, pp. 80-83
-
-
Noordermeer, J.1
Klingensmith, J.2
Perrimon, N.3
Nusse, R.4
-
46
-
-
0033611558
-
Axin prevents Wnt-3a-induced accumulation of beta-catenin
-
Kishida, M.; Koyama, S.; Kishida, S.; Matsubara, K.; Nakashima, S.; Higano, K.; Takada, R.; Takada, S.; Kikuchi, A. Axin prevents Wnt-3a-induced accumulation of beta-catenin. Oncogene 1999, 18, 979-985.
-
(1999)
Oncogene
, vol.18
, pp. 979-985
-
-
Kishida, M.1
Koyama, S.2
Kishida, S.3
Matsubara, K.4
Nakashima, S.5
Higano, K.6
Takada, R.7
Takada, S.8
Kikuchi, A.9
-
47
-
-
0033577732
-
Interaction of Axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription
-
Smalley, M. J.; Sara, E.; Paterson, H.; Naylor, S.; Cook, D.; Jayatilake, H.; Fryer, L. G.; Hutchinson, L.; Fry, M. J.; Dale, T. C. Interaction of Axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription. EMBO J. 1999, 18, 2823-2835.
-
(1999)
EMBO J
, vol.18
, pp. 2823-2835
-
-
Smalley, M.J.1
Sara, E.2
Paterson, H.3
Naylor, S.4
Cook, D.5
Jayatilake, H.6
Fryer, L.G.7
Hutchinson, L.8
Fry, M.J.9
Dale, T.C.10
-
48
-
-
0033993931
-
Interaction of dishevelled and Xenopus axin-related protein is required for Wnt signal transduction
-
Itoh, K.; Antipova, A.; Ratcliffe, M. J.; Sokol, S. Interaction of dishevelled and Xenopus axin-related protein is required for Wnt signal transduction. Mol. Cell. Biol. 2000, 20, 2228-2238.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 2228-2238
-
-
Itoh, K.1
Antipova, A.2
Ratcliffe, M.J.3
Sokol, S.4
-
49
-
-
0031856533
-
Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin
-
Hsu, S. C.; Galceran, J.; Grosschedl, R. Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin. Mol. Cell. Biol. 1998, 18, 4807-4818.
-
(1998)
Mol. Cell. Biol
, vol.18
, pp. 4807-4818
-
-
Hsu, S.C.1
Galceran, J.2
Grosschedl, R.3
-
50
-
-
1542347695
-
Convergence of Wnt, beta-catenin, and cadherin pathways
-
Nelson, W. J. and Nusse, R. Convergence of Wnt, beta-catenin, and cadherin pathways. Science 2004, 303, 1483-1487.
-
(2004)
Science
, vol.303
, pp. 1483-1487
-
-
Nelson, W.J.1
Nusse, R.2
-
51
-
-
4344584730
-
WNT and beta-catenin signalling: Diseases and therapies
-
Moon, R. T.; Kohn, A. D.; De Ferrari, G. V.; Kaykas, A. WNT and beta-catenin signalling: diseases and therapies. Nat. Rev. Genet. 2004,5, 691-701.
-
(2004)
Nat. Rev. Genet
, vol.5
, pp. 691-701
-
-
Moon, R.T.1
Kohn, A.D.2
de Ferrari, G.V.3
Kaykas, A.4
-
52
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis, P. Wnt signaling and cancer. Genes Dev. 2000, 14, 1837-1851.
-
(2000)
Genes Dev
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
53
-
-
0038359353
-
Caught up in a Wnt storm: Wnt signaling in cancer
-
Giles, R. H.; van Es, J. H.; Clevers, H. Caught up in a Wnt storm: Wnt signaling in cancer. Biochim. Biophys. Acta 2003, 1653, 1-24.
-
(2003)
Biochim. Biophys. Acta
, vol.1653
, pp. 1-24
-
-
Giles, R.H.1
van Es, J.H.2
Clevers, H.3
-
54
-
-
0037778008
-
The Wnt signaling pathway and its role in tumor development
-
Lustig, B. and Behrens, J. The Wnt signaling pathway and its role in tumor development. J. Cancer Res. Clin. Oncol. 2003, 129, 199-221.
-
(2003)
J. Cancer Res. Clin. Oncol
, vol.129
, pp. 199-221
-
-
Lustig, B.1
Behrens, J.2
-
56
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers, H. Wnt/beta-catenin signaling in development and disease. Cell 2006, 127, 469-480.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
57
-
-
70350023790
-
Targeting the WNT/beta-catenin/TCF/LEF1 axis in solid and haematological cancers: Multiplicity of therapeutic options
-
Gehrke, I.; Gandhirajan, R. K.; Kreuzer, K. A. Targeting the WNT/beta-catenin/TCF/LEF1 axis in solid and haematological cancers: Multiplicity of therapeutic options. Eur. J. Cancer 2009, 45, 2759-2767.
-
(2009)
Eur. J. Cancer
, vol.45
, pp. 2759-2767
-
-
Gehrke, I.1
Gandhirajan, R.K.2
Kreuzer, K.A.3
-
58
-
-
0037442760
-
Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis
-
Gunther, E. J.; Moody, S. E.; Belka, G. K.; Hahn, K. T.; Innocent, N.; Dugan, K. D.; Cardiff, R. D.; Chodosh, L. A. Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis. Genes Dev. 2003, 17, 488-501.
-
(2003)
Genes Dev
, vol.17
, pp. 488-501
-
-
Gunther, E.J.1
Moody, S.E.2
Belka, G.K.3
Hahn, K.T.4
Innocent, N.5
Dugan, K.D.6
Cardiff, R.D.7
Chodosh, L.A.8
-
59
-
-
0030613905
-
Wnt-10b directs hypermorphic development and transformation in mammary glands of male and female mice
-
Lane, T. F. and Philip, L. Wnt-10b directs hypermorphic development and transformation in mammary glands of male and female mice. Oncogene 1997, 15, 2133-2144.
-
(1997)
Oncogene
, vol.15
, pp. 2133-2144
-
-
Lane, T.F.1
Philip, L.2
-
60
-
-
0028272485
-
Differential expression of human Wnt gene-2, gene-3, gene-4, and gene-7B in human breast cell-lines and normal and disease states of human breast-tissue
-
Huguet, E. L.; Mcmahon, J. A.; Mcmahon, A. P.; Bicknell, R.; Harris, A. L. Differential expression of human Wnt gene-2, gene-3, gene-4, and gene-7B in human breast cell-lines and normal and disease states of human breast-tissue. Cancer Res. 1994, 54, 2615-2621.
-
(1994)
Cancer Res
, vol.54
, pp. 2615-2621
-
-
Huguet, E.L.1
McMahon, J.A.2
McMahon, A.P.3
Bicknell, R.4
Harris, A.L.5
-
62
-
-
3142590865
-
Wnt signaling and breast cancer
-
Howe, L. R.; Brown, A. M. C. Wnt signaling and breast cancer. Cancer Biol. Ther. 2004, 3, 36-41.
-
(2004)
Cancer Biol. Ther
, vol.3
, pp. 36-41
-
-
Howe, L.R.1
Brown, A.M.C.2
-
63
-
-
0035825119
-
Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription
-
Chen, S. Q.; Guttridge, D. C.; You, Z. B.; Zhang, Z. C.; Fribley, A.; Mayo, M. W.; Kitajewski, J.; Wang, C. Y. Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription. J. Cell Biol. 2001, 152, 87-96.
-
(2001)
J. Cell Biol
, vol.152
, pp. 87-96
-
-
Chen, S.Q.1
Guttridge, D.C.2
You, Z.B.3
Zhang, Z.C.4
Fribley, A.5
Mayo, M.W.6
Kitajewski, J.7
Wang, C.Y.8
-
64
-
-
78649262622
-
Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells
-
You, L.; He, B.; Xu, Z.; Uematsu, K.; Mazieres, J.; Mikami, I.; Reguart, N.; McComick, F.; Jablons, D. Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells. Lung Cancer 2005, 49, S76-S77.
-
(2005)
Lung Cancer
, vol.49
-
-
You, L.1
He, B.2
Xu, Z.3
Uematsu, K.4
Mazieres, J.5
Mikami, I.6
Reguart, N.7
McComick, F.8
Jablons, D.9
-
65
-
-
3442894128
-
An anti-Wnt-2 monoclonal antibody induces apoptosis in malignant melanoma cells and inhibits tumor growth
-
You, L.; He, B.; Xu, Z. D.; Uematsu, K.; Mazieres, J.; Fujii, N.; Mikami, I.; Reguart, N.; McIntosh, J. K.; Kashani-Sabet, M.; McCormick, F.; Jablons, D. M. An anti-Wnt-2 monoclonal antibody induces apoptosis in malignant melanoma cells and inhibits tumor growth. Cancer Res. 2004, 64, 5385-5389.
-
(2004)
Cancer Res
, vol.64
, pp. 5385-5389
-
-
You, L.1
He, B.2
Xu, Z.D.3
Uematsu, K.4
Mazieres, J.5
Fujii, N.6
Mikami, I.7
Reguart, N.8
McIntosh, J.K.9
Kashani-Sabet, M.10
McCormick, F.11
Jablons, D.M.12
-
66
-
-
16444374026
-
Constitutive activation of the Wnt/beta-catenin signalling pathway in acute myeloid leukaemia
-
Simon, M.; Grandage, V. L.; Linch, D. C.; Khwaja, A. Constitutive activation of the Wnt/beta-catenin signalling pathway in acute myeloid leukaemia. Oncogene 2005, 24, 2410-2420.
-
(2005)
Oncogene
, vol.24
, pp. 2410-2420
-
-
Simon, M.1
Grandage, V.L.2
Linch, D.C.3
Khwaja, A.4
-
67
-
-
34250678970
-
Targeting the beta-catenin/TCF transcriptional complex in the treatment of multiple myeloma
-
Sukhdeo, K.; Mani, M.; Zhang, Y.; Dutta, J.; Yasui, H.; Rooney, M. D.; Carrasco, D. E.; Zheng, M.; He, H.; Tai, Y. T.; Mitsiades, C.; Anderson, K. C.; Carrasco, D. R. Targeting the beta-catenin/TCF transcriptional complex in the treatment of multiple myeloma. Proc. Natl. Acad. Sci. USA 2007, 104, 7516-7521.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 7516-7521
-
-
Sukhdeo, K.1
Mani, M.2
Zhang, Y.3
Dutta, J.4
Yasui, H.5
Rooney, M.D.6
Carrasco, D.E.7
Zheng, M.8
He, H.9
Tai, Y.T.10
Mitsiades, C.11
Anderson, K.C.12
Carrasco, D.R.13
-
68
-
-
0035803371
-
Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia
-
Rosenwald, A.; Alizadeh, A. A.; Widhopf, G.; Simon, R.; Davis, R. E.; Yu, X.; Yang, L. M.; Pickeral, O. K.; Rassenti, L. Z.; Powell, J.; Botstein, D.; Byrd, J. C.; Grever, M. R.; Cheson, B. D.; Chiorazzi, N.; Wilson, W. H.; Kipps, T. J.; Brown, P. O.; Staudt, L. M. Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia. J. Exp. Med. 2001,194, 1639-1647.
-
(2001)
J. Exp. Med
, vol.194
, pp. 1639-1647
-
-
Rosenwald, A.1
Alizadeh, A.A.2
Widhopf, G.3
Simon, R.4
Davis, R.E.5
Yu, X.6
Yang, L.M.7
Pickeral, O.K.8
Rassenti, L.Z.9
Powell, J.10
Botstein, D.11
Byrd, J.C.12
Grever, M.R.13
Cheson, B.D.14
Chiorazzi, N.15
Wilson, W.H.16
Kipps, T.J.17
Brown, P.O.18
Staudt, L.M.19
-
69
-
-
0031596806
-
Identification of a Frizzled-like cysteine rich domain in the extracellular region of developmental receptor tyrosine kinases
-
Saldanha, J.; Singh, J.; Mahadevan, D. Identification of a Frizzled-like cysteine rich domain in the extracellular region of developmental receptor tyrosine kinases. Protein Sci. 1998, 7, 1632-1635.
-
(1998)
Protein Sci
, vol.7
, pp. 1632-1635
-
-
Saldanha, J.1
Singh, J.2
Mahadevan, D.3
-
70
-
-
42949121156
-
Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal,antigen and receptor for Wnt5a
-
Fukuda, T.; Chen, L.; Endo, T.; Tang, L.; Lu, D.; Castro, J. E.; Widhopf, G. F.; Rassenti, L. Z.; Cantwell, M. J.; Prussak, C. E.; Carson, D. A.; Kipps, T. J. Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal,antigen and receptor for Wnt5a. Proc. Natl. Acad. Sci. USA 2008,105, 3047-3052.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 3047-3052
-
-
Fukuda, T.1
Chen, L.2
Endo, T.3
Tang, L.4
Lu, D.5
Castro, J.E.6
Widhopf, G.F.7
Rassenti, L.Z.8
Cantwell, M.J.9
Prussak, C.E.10
Carson, D.A.11
Kipps, T.J.12
-
71
-
-
1542267803
-
Activation of the Wnt signaling pathway in chronic lymphocytic leukemia
-
Lu, D.; Zhao, Y.; Tawatao, R.; Cottam, H. B.; Sen, M.; Leoni, L. M.; Kipps, T. J.; Corr, M.; Carson, D. A. Activation of the Wnt signaling pathway in chronic lymphocytic leukemia. Proc. Natl. Acad. Sci. USA 2004, 101, 3118-3123.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3118-3123
-
-
Lu, D.1
Zhao, Y.2
Tawatao, R.3
Cottam, H.B.4
Sen, M.5
Leoni, L.M.6
Kipps, T.J.7
Corr, M.8
Carson, D.A.9
-
72
-
-
0032406715
-
Mechanisms of Wnt signaling in development
-
Wodarz, A.; Nusse, R. Mechanisms of Wnt signaling in development. Ann. Rev. Cell Dev. Biol. 1998, 14, 59-88.
-
(1998)
Ann. Rev. Cell Dev. Biol
, vol.14
, pp. 59-88
-
-
Wodarz, A.1
Nusse, R.2
-
73
-
-
64049104989
-
Dysregulation of Frizzled 6 is a critical component of B-cell leukemogenesis in a mouse model of chronic lymphocytic leukemia
-
Wu, Q. L.; Zierold, C.; Ranheim, E. A. Dysregulation of Frizzled 6 is a critical component of B-cell leukemogenesis in a mouse model of chronic lymphocytic leukemia. Blood 2009, 113, 3031-3039.
-
(2009)
Blood
, vol.113
, pp. 3031-3039
-
-
Wu, Q.L.1
Zierold, C.2
Ranheim, E.A.3
-
74
-
-
2442548880
-
The human frizzled 6 (HFz6) acts as a negative regulator of the canonical Wnt center dot beta-Catenin signaling cascade
-
Golan, T.; Yaniv, A.; Bafico, A.; Liu, G. Z.; Gazit, A. The human frizzled 6 (HFz6) acts as a negative regulator of the canonical Wnt center dot beta-Catenin signaling cascade. J. Biol. Chem. 2004, 279, 14879-14888.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 14879-14888
-
-
Golan, T.1
Yaniv, A.2
Bafico, A.3
Liu, G.Z.4
Gazit, A.5
-
75
-
-
0034727104
-
LDL-receptor-related proteins in Wnt signal transduction
-
Tamai, K.; Semenov, M.; Kato, Y.; Spokony, R.; Liu, C. M.; Katsuyama, Y.; Hess, F.; Saint-Jeannet, J. P.; He, X. LDL-receptor-related proteins in Wnt signal transduction. Nature 2000, 407, 530-535.
-
(2000)
Nature
, vol.407
, pp. 530-535
-
-
Tamai, K.1
Semenov, M.2
Kato, Y.3
Spokony, R.4
Liu, C.M.5
Katsuyama, Y.6
Hess, F.7
Saint-Jeannet, J.P.8
He, X.9
-
76
-
-
0035902050
-
LDL-receptor-related protein 6 is a receptor for Dickkopf proteins
-
Mao, B. Y.; Wu, W.; Li, Y.; Hoppe, D.; Stannek, P.; Glinka, A.; Niehrs, C. LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature 2001, 411, 321-325.
-
(2001)
Nature
, vol.411
, pp. 321-325
-
-
Mao, B.Y.1
Wu, W.2
Li, Y.3
Hoppe, D.4
Stannek, P.5
Glinka, A.6
Niehrs, C.7
-
77
-
-
0034657952
-
Hypermethylation of E-cadherin in leukemia
-
Melki, J. R.; Vincent, P. C.; Brown, R. D.; Clark, S. J. Hypermethylation of E-cadherin in leukemia. Blood 2000, 95, 3208-3213.
-
(2000)
Blood
, vol.95
, pp. 3208-3213
-
-
Melki, J.R.1
Vincent, P.C.2
Brown, R.D.3
Clark, S.J.4
-
78
-
-
77950524963
-
Aberrant splicing of the E-cadherin transcript is a novel mechanism of gene silencing in chronic lymphocytic leukemia cells
-
Sharma, S.; Lichtenstein, A. Aberrant splicing of the E-cadherin transcript is a novel mechanism of gene silencing in chronic lymphocytic leukemia cells. Blood 2009, 114, 4179-4185.
-
(2009)
Blood
, vol.114
, pp. 4179-4185
-
-
Sharma, S.1
Lichtenstein, A.2
-
79
-
-
0033523005
-
Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling
-
Bafico, A.; Gazit, A.; Pramila, T.; Finch, P. W.; Yaniv, A.; Aaronson, S. A. Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling. J. Biol. Chem. 1999, 274, 16180-16187.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 16180-16187
-
-
Bafico, A.1
Gazit, A.2
Pramila, T.3
Finch, P.W.4
Yaniv, A.5
Aaronson, S.A.6
-
80
-
-
11144356462
-
Epigenetic profiling in chronic lymphocytic leukemia reveals novel methylation targets
-
Rush, L. J.; Raval, A.; Funchain, P.; Johnson, A. J.; Smith, L.; Lucas, D. M.; Bembea, M.; Liu, T. H.; Heerema, N. A.; Rassenti, L.; Liyanarachchi, S.; Davuluri, R.; Byrd, J. C.; Plass, C. Epigenetic profiling in chronic lymphocytic leukemia reveals novel methylation targets. Cancer Res. 2004, 64, 2424-2433.
-
(2004)
Cancer Res
, vol.64
, pp. 2424-2433
-
-
Rush, L.J.1
Raval, A.2
Funchain, P.3
Johnson, A.J.4
Smith, L.5
Lucas, D.M.6
Bembea, M.7
Liu, T.H.8
Heerema, N.A.9
Rassenti, L.10
Liyanarachchi, S.11
Davuluri, R.12
Byrd, J.C.13
Plass, C.14
-
81
-
-
31544469759
-
CpG island methylation and expression of the secreted frizzled-related protein gene family in chronic lymphocytic leukemia
-
Liu, T. H.; Raval, A.; Chen, S. S.; Matkovic, J. J.; Byrd, J. C.; Plass, C. CpG island methylation and expression of the secreted frizzled-related protein gene family in chronic lymphocytic leukemia. Cancer Res. 2006, 66, 653-658.
-
(2006)
Cancer Res
, vol.66
, pp. 653-658
-
-
Liu, T.H.1
Raval, A.2
Chen, S.S.3
Matkovic, J.J.4
Byrd, J.C.5
Plass, C.6
-
82
-
-
56049111627
-
Epigenetic dysregulation of the Wnt signalling pathway in chronic lymphocytic leukaemia
-
Chim, C. S.; Pang, R.; Liang, R. Epigenetic dysregulation of the Wnt signalling pathway in chronic lymphocytic leukaemia. J. Clin. Pathol. 2008, 61, 1214-1219.
-
(2008)
J. Clin. Pathol
, vol.61
, pp. 1214-1219
-
-
Chim, C.S.1
Pang, R.2
Liang, R.3
-
83
-
-
67650912362
-
CpG island methylation patterns in chronic lymphocytic leukemia
-
Seeliger, B.; Wilop, S.; Osieka, R.; Galm, O.; Jost, E. CpG island methylation patterns in chronic lymphocytic leukemia. Leuk. Lymphoma 2009, 50, 419-426.
-
(2009)
Leuk. Lymphoma
, vol.50
, pp. 419-426
-
-
Seeliger, B.1
Wilop, S.2
Osieka, R.3
Galm, O.4
Jost, E.5
-
84
-
-
12144291274
-
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer
-
Suzuki, H.; Watkins, D. N.; Jair, K. W.; Schuebel, K. E.; Markowitz, S. D.; Chen, W. D.; Pretlow, T. P.; Bin, Y.; Akiyama, Y.; van Engeland, M.; Toyota, M.; Tokino, T.; Hinoda, Y.; Imai, K.; Herman, J. G.; Baylin, S. B. Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nat. Genetics 2004, 36, 417-422.
-
(2004)
Nat. Genetics
, vol.36
, pp. 417-422
-
-
Suzuki, H.1
Watkins, D.N.2
Jair, K.W.3
Schuebel, K.E.4
Markowitz, S.D.5
Chen, W.D.6
Pretlow, T.P.7
Bin, Y.8
Akiyama, Y.9
van Engeland, M.10
Toyota, M.11
Tokino, T.12
Hinoda, Y.13
Imai, K.14
Herman, J.G.15
Baylin, S.B.16
-
85
-
-
0038783316
-
Secreted antagonists of the Wnt signalling pathway
-
Kawano, Y.; Kypta, R. Secreted antagonists of the Wnt signalling pathway. J. Cell Science 2003, 116, 2627-2634.
-
(2003)
J. Cell Science
, vol.116
, pp. 2627-2634
-
-
Kawano, Y.1
Kypta, R.2
-
86
-
-
3142679453
-
Wnt inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer
-
Mazieres, J.; He, B.; You, L.; Xu, Z. D.; Lee, A. Y.; Mikami, I.; Reguart, N.; Rosell, R.; McCormick, F.; Jablons, D. M. Wnt inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer. Cancer Res. 2004, 64, 4717-4720.
-
(2004)
Cancer Res
, vol.64
, pp. 4717-4720
-
-
Mazieres, J.1
He, B.2
You, L.3
Xu, Z.D.4
Lee, A.Y.5
Mikami, I.6
Reguart, N.7
Rosell, R.8
McCormick, F.9
Jablons, D.M.10
-
87
-
-
33745823867
-
Infrequent Wnt inhibitory factor-1 (Wif-1) methylation in chronic lymphocytic leukemia
-
Chim, C. S.; Fung, T. K.; Wong, K. F.; Lau, J. S.; Liang, R. Infrequent Wnt inhibitory factor-1 (Wif-1) methylation in chronic lymphocytic leukemia. Leuk. Res. 2006, 30, 1135-1139.
-
(2006)
Leuk. Res
, vol.30
, pp. 1135-1139
-
-
Chim, C.S.1
Fung, T.K.2
Wong, K.F.3
Lau, J.S.4
Liang, R.5
-
88
-
-
33845526567
-
The Akt signaling pathway determines the different proliferative capacity of chronic lymphocytic leukemia B-cells from patients with progressive and stable disease
-
Longo, P. G.; Laurenti, L.; Gobessi, S.; Petlickovski, A.; Pelosi, M.; Chiusolo, P.; Sica, S.; Leone, G.; Efremov, D. G. The Akt signaling pathway determines the different proliferative capacity of chronic lymphocytic leukemia B-cells from patients with progressive and stable disease. Leukemia 2007, 21, 110-120.
-
(2007)
Leukemia
, vol.21
, pp. 110-120
-
-
Longo, P.G.1
Laurenti, L.2
Gobessi, S.3
Petlickovski, A.4
Pelosi, M.5
Chiusolo, P.6
Sica, S.7
Leone, G.8
Efremov, D.G.9
-
89
-
-
38349107623
-
The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells
-
Longo, P. G.; Laurenti, L.; Gobessi, S.; Sica, S.; Leone, G.; Efremov, D. G. The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells. Blood 2008, 111, 846-855.
-
(2008)
Blood
, vol.111
, pp. 846-855
-
-
Longo, P.G.1
Laurenti, L.2
Gobessi, S.3
Sica, S.4
Leone, G.5
Efremov, D.G.6
-
90
-
-
3042857530
-
PI3-kinase regulates survival of chronic lymphocytic leukemia B-cells by preventing caspase-8 activation
-
Plate, J. M. D. PI3-kinase regulates survival of chronic lymphocytic leukemia B-cells by preventing caspase-8 activation. Leuk. Lymphoma 2004, 45, 1519-1529.
-
(2004)
Leuk. Lymphoma
, vol.45
, pp. 1519-1529
-
-
Plate, J.M.D.1
-
91
-
-
0037111661
-
Constitutively activated phosphatidylinositol-3 kinase (PI-3K) is involved in the defect of apoptosis in B- CLL: Association with protein kinase C8
-
Ringshausen, I.; Schneller, F.; Bogner, C.; Hipp, S.; Duyster, J.; Peschel, C.; Decker, T. Constitutively activated phosphatidylinositol-3 kinase (PI-3K) is involved in the defect of apoptosis in B- CLL: association with protein kinase C8. Blood 2002, 100, 3741-3748.
-
(2002)
Blood
, vol.100
, pp. 3741-3748
-
-
Ringshausen, I.1
Schneller, F.2
Bogner, C.3
Hipp, S.4
Duyster, J.5
Peschel, C.6
Decker, T.7
-
92
-
-
0037100392
-
The B cell antigen receptor regulates the transcriptional activator beta-catenin via protein kinase C-mediated inhibition of glycogen synthase kinase-3
-
Christian, S. L.; Sims, P. V.; Gold, M. R. The B cell antigen receptor regulates the transcriptional activator beta-catenin via protein kinase C-mediated inhibition of glycogen synthase kinase-3. J. Immunol. 2002, 169, 758-769.
-
(2002)
J. Immunol
, vol.169
, pp. 758-769
-
-
Christian, S.L.1
Sims, P.V.2
Gold, M.R.3
-
93
-
-
0025794148
-
Lef-1 A, Gene Encoding A Lymphoid-Specific with Protein, An Hmg Domain, Regulates T-Cell Receptor-Alpha Enhancer Function
-
Travis, A.; Amsterdam, A.; Belanger, C.; Grosschedl, R. Lef-1, A Gene Encoding A Lymphoid-Specific with Protein, An Hmg Domain, Regulates T-Cell Receptor-Alpha Enhancer Function. Genes Dev. 1991, 5, 880-894.
-
(1991)
Genes Dev
, vol.5
, pp. 880-894
-
-
Travis, A.1
Amsterdam, A.2
Belanger, C.3
Grosschedl, R.4
-
94
-
-
27844465017
-
Variation of LEF-1 mRNA expression in low-grade B-cell non-Hodgkin's lymphoma
-
Howe, D.; Bromidge, T. Variation of LEF-1 mRNA expression in low-grade B-cell non-Hodgkin's lymphoma. Leuk. Res. 2006, 30, 29-32.
-
(2006)
Leuk. Res
, vol.30
, pp. 29-32
-
-
Howe, D.1
Bromidge, T.2
-
95
-
-
33847185954
-
Gene expression profiling of B lymphocytes and plasma cells from Waldenstrom's macroglobulinemia: Comparison with expression patterns of the same cell counterparts from chronic lymphocytic leukemia, multiple myeloma and normal individuals
-
Gutierrez, N. C.; Ocio, E. M.; Rivas, J. D. L.; Maiso, P.; Delgado, M.; Ferminan, E.; Arcos, M. J.; Sanchez, M. L.; Hernandez, J. M.; Miguel, J. F. S. Gene expression profiling of B lymphocytes and plasma cells from Waldenstrom's macroglobulinemia: comparison with expression patterns of the same cell counterparts from chronic lymphocytic leukemia, multiple myeloma and normal individuals. Leukemia 2007, 21, 541-549.
-
(2007)
Leukemia
, vol.21
, pp. 541-549
-
-
Gutierrez, N.C.1
Ocio, E.M.2
Rivas, J.D.L.3
Maiso, P.4
Delgado, M.5
Ferminan, E.6
Arcos, M.J.7
Sanchez, M.L.8
Hernandez, J.M.9
Miguel, J.F.S.10
-
96
-
-
0037358145
-
Identification of a global gene expression signature of B-chronic lymphocytic leukemia
-
Jelinek, D. F.; Tschumper, R. C.; Stolovitzky, G. A.; Iturria, S. J.; Tu, Y. H.; Lepre, J.; Shah, N.; Kay, N. E. Identification of a global gene expression signature of B-chronic lymphocytic leukemia. Mol. Cancer Res.2003, 1, 346-361.
-
(2003)
Mol. Cancer Res
, vol.1
, pp. 346-361
-
-
Jelinek, D.F.1
Tschumper, R.C.2
Stolovitzky, G.A.3
Iturria, S.J.4
Tu, Y.H.5
Lepre, J.6
Shah, N.7
Kay, N.E.8
-
97
-
-
25844482087
-
Epigenetic treatment of hematopoietic malignancies: In vivo targets of demethylating agents
-
Claus, R.; Almstedt, M.; Lubbert, M. Epigenetic treatment of hematopoietic malignancies: In vivo targets of demethylating agents. Semin. Oncol. 2005, 32, 511-520.
-
(2005)
Semin. Oncol
, vol.32
, pp. 511-520
-
-
Claus, R.1
Almstedt, M.2
Lubbert, M.3
-
98
-
-
33947281469
-
Survival advantage with decitabine versus intensive chemotherapy in patients with higher risk myelodysplastic syndrome - Comparison with historical experience
-
Kantarjian, H. M.; O'Brien, S.; Huang, X. L.; Garcia-Manero, G.; Ravandi, F.; Cortes, J.; Shan, J. Q.; Davisson, J.; Bueso-Ramos, C. E.; Issa, J. P. Survival advantage with decitabine versus intensive chemotherapy in patients with higher risk myelodysplastic syndrome - Comparison with historical experience. Cancer 2007, 109, 1133-1137.
-
(2007)
Cancer
, vol.109
, pp. 1133-1137
-
-
Kantarjian, H.M.1
O'Brien, S.2
Huang, X.L.3
Garcia-Manero, G.4
Ravandi, F.5
Cortes, J.6
Shan, J.Q.7
Davisson, J.8
Bueso-Ramos, C.E.9
Issa, J.P.10
-
99
-
-
21844443820
-
Decitabine in chronic leukemias
-
Issa, J. P.; Byrd, J. C. Decitabine in chronic leukemias. Semin. Hematol. 2009, 42, 43-49.
-
(2009)
Semin. Hematol
, vol.42
, pp. 43-49
-
-
Issa, J.P.1
Byrd, J.C.2
-
100
-
-
0026725175
-
Selective toxicity of ethacrynic-acid towards lymphocytes of chronic lymphocytic-leukemia In vitro
-
Twentyman, P. R.; Lambert, E.; Muller, M.; Rees, J. K. H. Selective toxicity of ethacrynic-acid towards lymphocytes of chronic lymphocytic-leukemia In vitro. Leukemia 1992, 6, 726-728.
-
(1992)
Leukemia
, vol.6
, pp. 726-728
-
-
Twentyman, P.R.1
Lambert, E.2
Muller, M.3
Rees, J.K.H.4
-
101
-
-
58549110011
-
Amide derivatives of ethacrynic acid: Synthesis and evaluation as antagonists of Wnt/beta-catenin signaling and CLL cell survival
-
Jin, G. Y.; Lu, D. S.; Yao, S. Y.; Wu, C. C. N.; Liu, J. X.; Carson, D. A.; Cottam, H. B. Amide derivatives of ethacrynic acid: Synthesis and evaluation as antagonists of Wnt/beta-catenin signaling and CLL cell survival. Bioorg. Med. Chem. Lett. 2009, 19, 606-609.
-
(2009)
Bioorg. Med. Chem. Lett
, vol.19
, pp. 606-609
-
-
Jin, G.Y.1
Lu, D.S.2
Yao, S.Y.3
Wu, C.C.N.4
Liu, J.X.5
Carson, D.A.6
Cottam, H.B.7
-
102
-
-
1642512639
-
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex
-
Lepourcelet, M.; Chen, Y. N.; France, D. S.; Wang, H.; Crews, P.; Petersen, F.; Bruseo, C.; Wood, A. W.; Shivdasani, R. A. Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex. Cancer Cell 2004, 5, 91-102.
-
(2004)
Cancer Cell
, vol.5
, pp. 91-102
-
-
Lepourcelet, M.1
Chen, Y.N.2
France, D.S.3
Wang, H.4
Crews, P.5
Petersen, F.6
Bruseo, C.7
Wood, A.W.8
Shivdasani, R.A.9
-
103
-
-
77951230705
-
Small molecule antagonists of Tcf4/beta-catenin complex inhibit the growth of HCC cells in vitro and in vivo
-
Wei, W.; Chua, M. S.; Grepper, S.; So, S. Small molecule antagonists of Tcf4/beta-catenin complex inhibit the growth of HCC cells in vitro and in vivo. Int. J. Cancer 2010, 126, 2426-36.
-
(2010)
Int. J. Cancer
, vol.126
, pp. 2426-2436
-
-
Wei, W.1
Chua, M.S.2
Grepper, S.3
So, S.4
-
104
-
-
49249137734
-
The T cell factor/beta-catenin antagonist PKF115-584 inhibits proliferation of adrenocortical carcinoma cells
-
Doghman, M.; Cazareth, J.; Lalli, E. The T cell factor/beta-catenin antagonist PKF115-584 inhibits proliferation of adrenocortical carcinoma cells. J. Clin. Endocrinol. Metab. 2008, 93, 3222-3225.
-
(2008)
J. Clin. Endocrinol. Metab
, vol.93
, pp. 3222-3225
-
-
Doghman, M.1
Cazareth, J.2
Lalli, E.3
-
105
-
-
58849147900
-
Small molecule inhibitors of WNT signaling effectively induce apoptosis in acute myeloid leukemia cells
-
Minke, K. S.; Staib, P.; Puetter, A.; Gehrke, I.; Gandhirajan, R. K.; Schlosser, A.; Schmitt, E. K.; Hallek, M.; Kreuzer, K. A. Small molecule inhibitors of WNT signaling effectively induce apoptosis in acute myeloid leukemia cells. Eur. J. Haematol. 2009, 82, 165-175.
-
(2009)
Eur. J. Haematol
, vol.82
, pp. 165-175
-
-
Minke, K.S.1
Staib, P.2
Puetter, A.3
Gehrke, I.4
Gandhirajan, R.K.5
Schlosser, A.6
Schmitt, E.K.7
Hallek, M.8
Kreuzer, K.A.9
-
106
-
-
77951675861
-
Small molecule inhibitors of Wnt/beta-catenin/lef-1 signaling induces apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo
-
Gandhirajan, R. K.; Staib, P. A.; Minke, K.; Gehrke, I.; Plickert, G.; Schlosser, A.; Schmitt, E. K.; Hallek, M.; Kreuzer, K. A. Small molecule inhibitors of Wnt/beta-catenin/lef-1 signaling induces apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo. Neoplasia 2010, 12, 326-335.
-
(2010)
Neoplasia
, vol.12
, pp. 326-335
-
-
Gandhirajan, R.K.1
Staib, P.A.2
Minke, K.3
Gehrke, I.4
Plickert, G.5
Schlosser, A.6
Schmitt, E.K.7
Hallek, M.8
Kreuzer, K.A.9
-
107
-
-
29444449618
-
Repression of beta-catenin function in malignant cells by nonsteroidal antiinflammatory drugs
-
Lu, D. S.; Cottam, H. B.; Corr, M.; Carson, D. A. Repression of beta-catenin function in malignant cells by nonsteroidal antiinflammatory drugs. Proc. Natl. Acad. Sci. USA 2005, 102, 18567-18571.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 18567-18571
-
-
Lu, D.S.1
Cottam, H.B.2
Corr, M.3
Carson, D.A.4
-
108
-
-
3343010645
-
Effect of nonsteroidal anti-inflammatory drugs on beta-catenin protein levels and catenin-related transcription in human colorectal cancer cells
-
Gardner, S. H.; Hawcroft, G.; Hull, M. A. Effect of nonsteroidal anti-inflammatory drugs on beta-catenin protein levels and catenin-related transcription in human colorectal cancer cells. Br. J. Cancer 2004,91, 153-163.
-
(2004)
Br. J. Cancer
, vol.91
, pp. 153-163
-
-
Gardner, S.H.1
Hawcroft, G.2
Hull, M.A.3
-
109
-
-
78649275472
-
Cytotoxic effect of Sdx-308, analogue of R-enantiomer of etodolac, in combination with purine analogues or monoclonal antibodies on ex vivo B-cell chronic lymphocytic leukemia cells
-
Robak, P.; Robak, T.; Smolewski, P.; Linke, A.; Cebula, B. Cytotoxic effect of Sdx-308, analogue of R-enantiomer of etodolac, in combination with purine analogues or monoclonal antibodies on ex vivo B-cell chronic lymphocytic leukemia cells. Haematologica 2008,93, 219-219.
-
(2008)
Haematologica
, vol.93
, pp. 219-219
-
-
Robak, P.1
Robak, T.2
Smolewski, P.3
Linke, A.4
Cebula, B.5
-
110
-
-
3042837373
-
Nitric-oxide-donating NSAIDs as agents for cancer prevention
-
Rigas, B.; Kashfi, K. Nitric-oxide-donating NSAIDs as agents for cancer prevention. Trends Mol. Med. 2004, 10, 324-330.
-
(2004)
Trends Mol. Med
, vol.10
, pp. 324-330
-
-
Rigas, B.1
Kashfi, K.2
-
111
-
-
0242300130
-
Nitric oxide-donating aspirin inhibits beta-catenin T cell factor (TCF) signaling in SW480 colon cancer cells by disrupting the nuclear beta-catenin-TCF association
-
Nath, N.; Kashfi, K.; Chen, J.; Rigas, B. Nitric oxide-donating aspirin inhibits beta-catenin T cell factor (TCF) signaling in SW480 colon cancer cells by disrupting the nuclear beta-catenin-TCF association. Proc. Natl. Acad. Sci. USA 2003, 100, 12584-12589.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 12584-12589
-
-
Nath, N.1
Kashfi, K.2
Chen, J.3
Rigas, B.4
-
112
-
-
4344587136
-
A small molecule inhibitor of beta- catenin/cyclic AMP response element-binding protein transcription
-
Emami, K. H.; Nguyen, C.; Ma, H.; Kim, D. H.; Jeong, K. W.; Eguchi, M.; Moon, R. T.; Teo, J. L.; Oh, S. W.; Kim, H. Y.; Moon, S. H.; Ha, J. R.; Kahn, M. A small molecule inhibitor of beta- catenin/cyclic AMP response element-binding protein transcription. Proc. Natl. Acad. Sci. USA 2004, 101, 12682-1268.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 12682-11268
-
-
Emami, K.H.1
Nguyen, C.2
Ma, H.3
Kim, D.H.4
Jeong, K.W.5
Eguchi, M.6
Moon, R.T.7
Teo, J.L.8
Oh, S.W.9
Kim, H.Y.10
Moon, S.H.11
Ha, J.R.12
Kahn, M.13
-
113
-
-
74249094451
-
Oral fludarabine in untreated patients with B-cell chronic lymphocytic leukemia
-
Shustik, C.; Turner, A. R.; Desjardins, P.; Fernandez, L.; Rubin, S.; Larratt, L.; Duncan, A. M. V.; Rizi, D.; Sadura, A.; Shepherd, L.; Li, D.; Rassenti, L.; Kipps, T. Oral fludarabine in untreated patients with B-cell chronic lymphocytic leukemia. Leukemia 2010, 24, 237-239.
-
(2010)
Leukemia
, vol.24
, pp. 237-239
-
-
Shustik, C.1
Turner, A.R.2
Desjardins, P.3
Fernandez, L.4
Rubin, S.5
Larratt, L.6
Duncan, A.M.V.7
Rizi, D.8
Sadura, A.9
Shepherd, L.10
Li, D.11
Rassenti, L.12
Kipps, T.13
-
114
-
-
19944429446
-
Addition of rituximab to fludarabine may prolong progression-free survival and overall survival in patients with previously untreated chronic lymphocytic leukemia: An updated retrospective comparative analysis of CALGB 9712 and CALGB 9011
-
Byrd, J. C.; Rai, K.; Peterson, B. L.; Appelbaum, F. R.; Morrison, V. A.; Kolitz, J. E.; Shepherd, L.; Hines, J. D.; Schiffer, C. A.; Larson, R. A. Addition of rituximab to fludarabine may prolong progression-free survival and overall survival in patients with previously untreated chronic lymphocytic leukemia: an updated retrospective comparative analysis of CALGB 9712 and CALGB 9011. Blood 2005, 105, 49-53.
-
(2005)
Blood
, vol.105
, pp. 49-53
-
-
Byrd, J.C.1
Rai, K.2
Peterson, B.L.3
Appelbaum, F.R.4
Morrison, V.A.5
Kolitz, J.E.6
Shepherd, L.7
Hines, J.D.8
Schiffer, C.A.9
Larson, R.A.10
-
115
-
-
51449089880
-
Liposomal packaging generates Wnt Protein with in vivo biological activity
-
Morrell, N. T.; Leucht, P.; Zhao, L. D.; Kim, J. B.; ten Berge, D.; Ponnusamy, K.; Carre, A. L.; Dudek, H.; Zachlederova, M.; McElhaney, M.; Brunton, S.; Gunzner, J.; Callow, M.; Polakis, P.; Costa, M.; Zhang, X. M.; Helms, J. A.; Nusse, R. Liposomal packaging generates Wnt Protein with in vivo biological activity. PLoS One 2008,3, e2930.
-
(2008)
PLoS One
, vol.e2930
, pp. 3
-
-
Morrell, N.T.1
Leucht, P.2
Zhao, L.D.3
Kim, J.B.4
ten Berge, D.5
Ponnusamy, K.6
Carre, A.L.7
Dudek, H.8
Zachlederova, M.9
McElhaney, M.10
Brunton, S.11
Gunzner, J.12
Callow, M.13
Polakis, P.14
Costa, M.15
Zhang, X.M.16
Helms, J.A.17
Nusse, R.18
-
116
-
-
70350489312
-
The anti-helminthic niclosamide inhibits Wnt/Frizzled1 signaling
-
Chen, M. Y.; Wang, J. B.; Lu, J. Y.; Bond, M. C.; Ren, X. R.; Lyerly, H. K.; Barak, L. S.; Chen, W. The anti-helminthic niclosamide inhibits Wnt/Frizzled1 signaling. Biochemistry 2009, 48, 10267-10274.
-
(2009)
Biochemistry
, vol.48
, pp. 10267-10274
-
-
Chen, M.Y.1
Wang, J.B.2
Lu, J.Y.3
Bond, M.C.4
Ren, X.R.5
Lyerly, H.K.6
Barak, L.S.7
Chen, W.8
-
117
-
-
28244496603
-
Identification of a specific inhibitor of the dishevelled PDZ domain
-
Shan, J. F.; Shi, D. L.; Wang, J. M.; Zheng, J. Identification of a specific inhibitor of the dishevelled PDZ domain. Biochemistry 2005,44, 15495-15503.
-
(2005)
Biochemistry
, vol.44
, pp. 15495-15503
-
-
Shan, J.F.1
Shi, D.L.2
Wang, J.M.3
Zheng, J.4
-
118
-
-
58249122326
-
Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
-
Chen, B. Z.; Dodge, M. E.; Tang, W.; Lu, J. M.; Ma, Z. Q.; Fan, C. W.; Wei, S. G.; Hao, W. N.; Kilgore, J.; Williams, N. S.; Roth, M. G.; Amatruda, J. F.; Chen, C.; Lum, L. Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. Nat. Chem. Biol. 2009, 5, 100-107.
-
(2009)
Nat. Chem. Biol
, vol.5
, pp. 100-107
-
-
Chen, B.Z.1
Dodge, M.E.2
Tang, W.3
Lu, J.M.4
Ma, Z.Q.5
Fan, C.W.6
Wei, S.G.7
Hao, W.N.8
Kilgore, J.9
Williams, N.S.10
Roth, M.G.11
Amatruda, J.F.12
Chen, C.13
Lum, L.14
-
119
-
-
12844274417
-
Quercetin, a potent inhibitor against beta-catenin/Tcf signaling in SW480 colon cancer cells
-
Park, C. H.; Chang, J. Y.; Hahm, E. R.; Park, S.; Kim, H. K.; Yang, C. H. Quercetin, a potent inhibitor against beta-catenin/Tcf signaling in SW480 colon cancer cells. Biochem. Biophys. Res. Commun. 2005,328, 227-234.
-
(2005)
Biochem. Biophys. Res. Commun
, vol.328
, pp. 227-234
-
-
Park, C.H.1
Chang, J.Y.2
Hahm, E.R.3
Park, S.4
Kim, H.K.5
Yang, C.H.6
-
120
-
-
68549112883
-
2,4-Diamino-quinazolines as inhibitors of beta-catenin/Tcf-4 pathway: Potential treatment for colorectal cancer
-
Chen, Z. C.; Venkatesan, A. M.; Dehnhardt, C. M.; Dos Santos, O.; os Santos, E.; yral-Kaloustian, S.; Chen, L.; Geng, Y.; Arndt, K. T.; Lucas, J.; Chaudhary, I.; Mansour, T. S. 2,4-Diamino-quinazolines as inhibitors of beta-catenin/Tcf-4 pathway: Potential treatment for colorectal cancer. Bioorg. Med. Chem. Lett. 2009, 19, 4980-4983.
-
(2009)
Bioorg. Med. Chem. Lett
, vol.19
, pp. 4980-4983
-
-
Chen, Z.C.1
Venkatesan, A.M.2
Dehnhardt, C.M.3
Dos Santos, O.4
os Santos, E.5
Yral-Kaloustian, S.6
Chen, L.7
Geng, Y.8
Arndt, K.T.9
Lucas, J.10
Chaudhary, I.11
Mansour, T.S.12
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