Hypermethylation of E-cadherin in leukemia

Blood

Volumn 95, Issue 10, 2000, Pages 3208-3213

  Melki, John R ^b   Vincent, Paul C ^b   Brown, Ross D ^b   Clark, Susan J ^a  

^a CSIRO   (Australia)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; UVOMORULIN;

ALLELISM; ARTICLE; GENE INACTIVATION; GENE SEQUENCE; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; LEUKEMIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METHYLATION;

EID: 0034657952     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v95.10.3208.010k02_3208_3213     Document Type: Article

References (32)

1. Jankowski JA, Bedford FK, Kim YS. Changes in gene structure and regulation of E-cadherin during epithelial development, differentiation, and disease. Prog Nucleic Acid Res Mol Biol. 1997; 57:187.
2. Paul R, Ewing CM, Jarrard DF, Isaacs WB. The cadherin cell-cell adhesion pathway in prostate cancer progression. Br J Urol. 1997;79:37.
3. Graff JR, Herman JG, Lapidus RG, et al. E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas. Cancer Res. 1995;55:5195.
4. Kanai Y, Ushijima S, Hui AM, et al. The E-cadherin gene is silenced by CpG methylation in human hepatocellular carcinomas. Int J Cancer. 1997;71:355.
5. Yoshiura K, Kanai Y, Ochiai A, Shimoyama Y, Sugimura T, Hirohashi S. Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas. Proc Natl Acad Sci U S A. 1995;92:7416.
6. Armeanu S, Buhring HJ, Reuss-Borst M, Muller CA, Klein G. E-cadherin is functionally involved in the maturation of the erythroid lineage. J Cell Biol. 1995;131:243.
7. Buhring HJ, Muller T, Herbst R, et al. The adhesion molecule E-cadherin and a surface antigen recognized by the antibody 9C4 are selectively expressed on erythroid cells of defined maturational stages. Leukemia. 1996;10:106.
8. Ji X, Woodard AS, Rimm DL, Fearon ER. Transcriptional defects underlie loss of E-cadherin expression in breast cancer. Cell Growth Differ. 1997;8:773.
9. Hiraguri S, Godfrey T, Nakamura H, et al. Mechanisms of inactivation of E-cadherin in breast cancer cell lines. Cancer Res. 1998;58:1972.
10. Hennig G, Behrens J, Truss M, Frisch S, Reichmann E, Birchmeier W. Progression of carcinoma cells is associated with alterations in chromalin structure and factor binding at the E-cadherin promoter in vivo. Oncogene. 1995;11:475.
11. Guilford P, Hopkins J, Harraway J, et al. E-cadherin germline mutations in familial gastric cancer. Nature. 1998;392:402.
12. Saito Y, Takazawa H, Uzawa K, Tanzawa H, Sato K. Reduced expression of E-cadherin in oral squamous cell carcinoma: relationship with DNA methylation of 5′ CpG island. Int J Oncol. 1998; 12:293.
13. Turker MS, Bestor TH. Formation of methylation patterns in the mammalian genome [see comments]. Mutat Res. 1997;386:119.
14. Holliday R. DNA methylation and epigenetic inheritance. Philos Trans R Soc Lond B Biol Sci. 1990;326:329.
15. Melki J, Vincent P, Clark S. Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia. Cancer Res. 1999;59:3730.
16. Issa JP, Baylin SB, Herman JG. DNA methylation changes in hematologic malignancies: biologic and clinical implications. Leukemia. 1997;11:S7.
17. Melki J, Warnecke P, Vincent P, Clark S. Increased DNA methyltransferase expression in leukemia. Leukemia. 1998;12:311.
18. Baylin SB, Herman JG, Graff JR, Vertino PM, Issa JP. Alterations in DNA methylation: a fundamental aspect of neoplasia. Adv Cancer Res. 1998;72: 141.
19. Bird AP. CpG-rich islands and the function of DNA methylation. Nature. 1986;321:209.
20. Frommer M, McDonald LE, Millar DS, et al. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc Natl Acad Sci U S A. 1992;89: 1827.
21. Clark SJ, Harrison J, Paul CL, Frommer M. High sensitivity mapping of methylated cytosines. Nucleic Acids Res. 1994;22:2990.
22. Clark SJ, Frommer M. Bisulphite genomic sequencing of methylated cytosines. In: Taylor GR, ed. Laboratory Methods for the Detection of Mutations and Polymorphisms in DNA. New York: CRC Press; 1997:151.
23. Warnecke PM, Stirzaker C, Melki JR, Millar DS, Paul CL, Clark S. Detection and measurement of PCR bias in quantitative methylation analysis of bisulphite-treated DNA. Nucleic Acids Res. 1997; 25:4422.
24. Levy JE, Jin O, Fujiwara Y, Kuo F, Andrews NC. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Nat Genet. 1999;21:396.
25. Berx G, Staes K, van Hengel J, et al. Cloning and characterization of the human invasion suppressor gene E-cadherin (CDH1). Genomics. 1995; 26:281.
26. Graff JR, Herman JG, Myohanen S, Baylin SB, Vertino PM. Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de novo methylation. J Biol Chem. 1997;272:22,322.
27. Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci U S A. 1996;93:9821.
28. To LB, Haylock DN, Simmons PJ, Juttner CA. The biology and clinical uses of blood stem cells. Blood. 1997;89:2233.
29. Fliedner TM. The role of blood stem cells in hematopoietic cell renewal. Stem Cells. 1998;16: 361.
30. Millar DS, Ow KK, Paul CL, Russell PJ, Molloy PL, Clark SJ. Detailed methylation analysis of the glutathione S-transferase Pi (GSTP1) gene in prostate cancer. Oncogene. 1999;18:1313.
31. Stirzaker C, Millar DS, Paul CL, et al. Extensive DNA methylation spanning the Rb promoter in retinoblastoma tumors. Cancer Res. 1997;57: 2229.
32. Warnecke PM, Clark SJ. DNA methylation profile of the mouse skeletal alpha-actin promoter during development and differentiation. Mol Cell Biol. 1999;19:164