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Volumn 3, Issue 1, 2004, Pages 36-41

Wht signaling and breast cancer

Author keywords

Breast cancer; Mutations; Pathway; Wnt proteins; Wnt signaling; catenin

Indexed keywords

APC PROTEIN; AXIN; BETA CATENIN; RNA; WNT PROTEIN; CATNB PROTEIN, MOUSE; CTNNB1 PROTEIN, HUMAN; CYTOSKELETON PROTEIN; ONCOPROTEIN; TRANSACTIVATOR PROTEIN;

EID: 3142590865     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.3.1.561     Document Type: Review
Times cited : (290)

References (76)
  • 1
    • 0031456158 scopus 로고    scopus 로고
    • Wnt signaling: A common theme in animal development
    • Cadigan KM, Nusse R. Wnt signaling: a common theme in animal development. Genes Dev 1997;11:3286-305.
    • (1997) Genes Dev , vol.11 , pp. 3286-3305
    • Cadigan, K.M.1    Nusse, R.2
  • 4
    • 0037737728 scopus 로고    scopus 로고
    • A role for Wnt signalling in self-renewal of haematopoietic stem cells
    • Reya T, Duncan AW, Ailles L, et al. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature 2003; 423:409-14.
    • (2003) Nature , vol.423 , pp. 409-414
    • Reya, T.1    Duncan, A.W.2    Ailles, L.3
  • 5
    • 0037737726 scopus 로고    scopus 로고
    • Wnt proteins are lipid-modified and can act as stem cell growth factors
    • Willert K, Brown JD, Danenberg E, et al. Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 2003; 423:448-52.
    • (2003) Nature , vol.423 , pp. 448-452
    • Willert, K.1    Brown, J.D.2    Danenberg, E.3
  • 6
    • 0026772731 scopus 로고
    • Wnt genes
    • Nusse R, Varmus HE. Wnt genes. Cell 1992; 69:1073-87.
    • (1992) Cell , vol.69 , pp. 1073-1087
    • Nusse, R.1    Varmus, H.E.2
  • 7
    • 0035719960 scopus 로고    scopus 로고
    • Wnt signaling in breast cancer: Have we come full circle?
    • Brown AMC. Wnt signaling in breast cancer: have we come full circle? Breast Cancer Res 2001;3:351-5.
    • (2001) Breast Cancer Res , vol.3 , pp. 351-355
    • Brown, A.M.C.1
  • 8
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis P. Wnt signaling and cancer. Genes Dev 2000; 14:1837-51.
    • (2000) Genes Dev , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 10
    • 0035656179 scopus 로고    scopus 로고
    • Expression of WNT14 and WNT14B mRNAs in human cancer, up-regulation of WNT14 by IFNgamma and up-regulation of WNT14B by beta-estradiol
    • Kirikoshi H, Sekihara H, Katoh M. Expression of WNT14 and WNT14B mRNAs in human cancer, up-regulation of WNT14 by IFNgamma and up-regulation of WNT14B by beta-estradiol. Int J Oncol 2001; 19:1221-5.
    • (2001) Int J Oncol , vol.19 , pp. 1221-1225
    • Kirikoshi, H.1    Sekihara, H.2    Katoh, M.3
  • 12
    • 0034649645 scopus 로고    scopus 로고
    • Wnt signaling: An embarrassment of receptors
    • Bejsovec A. Wnt signaling: An embarrassment of receptors. Curr Biol 2000; 10:R919-R22.
    • (2000) Curr Biol , vol.10
    • Bejsovec, A.1
  • 13
    • 0042131956 scopus 로고    scopus 로고
    • A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor
    • Liu G, Bafico A, Harris VK, Aaronson SA. A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor. Mol Cell Biol 2003; 23:5825-35.
    • (2003) Mol Cell Biol , vol.23 , pp. 5825-5835
    • Liu, G.1    Bafico, A.2    Harris, V.K.3    Aaronson, S.A.4
  • 14
    • 0032843036 scopus 로고    scopus 로고
    • Cadherins and catenins: Role in signal transduction and tumor progression
    • Behrens J. Cadherins and catenins: role in signal transduction and tumor progression. Cancer Metastasis Rev 1999; 18:15-30.
    • (1999) Cancer Metastasis Rev , vol.18 , pp. 15-30
    • Behrens, J.1
  • 15
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996; 87:159-70.
    • (1996) Cell , vol.87 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 16
    • 0030949463 scopus 로고    scopus 로고
    • Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
    • Morin PJ, Sparks AB, Korinek V, et al. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 1997; 275:1787-90.
    • (1997) Science , vol.275 , pp. 1787-1790
    • Morin, P.J.1    Sparks, A.B.2    Korinek, V.3
  • 18
    • 0020216124 scopus 로고
    • Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
    • Nusse R, Varmus HE. Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome. Cell 1982; 31:99-109.
    • (1982) Cell , vol.31 , pp. 99-109
    • Nusse, R.1    Varmus, H.E.2
  • 19
    • 0021270667 scopus 로고
    • Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15
    • Nusse R, van Ooyen A, Cox D, Fung YK, Varmus HE. Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15. Nature 1984; 307:131-6.
    • (1984) Nature , vol.307 , pp. 131-136
    • Nusse, R.1    Van Ooyen, A.2    Cox, D.3    Fung, Y.K.4    Varmus, H.E.5
  • 20
    • 0035972159 scopus 로고    scopus 로고
    • Delta-N89beta-catenin induces precocious development, differentiation, and neoplasia in mammary gland
    • Imbert A, Eelkema R, Jordan S, Feiner H, Cowin P. Delta-N89beta-catenin induces precocious development, differentiation, and neoplasia in mammary gland. J Cell Biol 2001; 153:555-68.
    • (2001) J Cell Biol , vol.153 , pp. 555-568
    • Imbert, A.1    Eelkema, R.2    Jordan, S.3    Feiner, H.4    Cowin, P.5
  • 21
    • 0035939818 scopus 로고    scopus 로고
    • Beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland
    • Michaelson JS, Leder P. beta-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland. Oncogene 2001; 20:5093-9.
    • (2001) Oncogene , vol.20 , pp. 5093-5099
    • Michaelson, J.S.1    Leder, P.2
  • 22
    • 0024162530 scopus 로고
    • Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice
    • Tsukamoto AS, Grosschedl R, Guzman RC, Parslow T, Varmus HE. Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. Cell 1988; 55:619-25.
    • (1988) Cell , vol.55 , pp. 619-625
    • Tsukamoto, A.S.1    Grosschedl, R.2    Guzman, R.C.3    Parslow, T.4    Varmus, H.E.5
  • 23
    • 0034840950 scopus 로고    scopus 로고
    • Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC
    • Ryo A, Nakamura M, Wulf G, Liou YC, Lu KP. Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC. Nat Cell Biol 2001; 3:793-801.
    • (2001) Nat Cell Biol , vol.3 , pp. 793-801
    • Ryo, A.1    Nakamura, M.2    Wulf, G.3    Liou, Y.C.4    Lu, K.P.5
  • 24
    • 0034636153 scopus 로고    scopus 로고
    • Beta-catenin, a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression
    • USA
    • Lin SY, Xia W, Wang JC, et al. Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression. Proc Natl Acad Sci USA 2000; 97:4262-6.
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 4262-4266
    • Lin, S.Y.1    Xia, W.2    Wang, J.C.3
  • 25
    • 0033976526 scopus 로고    scopus 로고
    • Involvement of adenomatous polyposis coli (APC)/beta-catenin signalling in human breast cancer
    • Jonsson M, Borg A, Nilbert M, Andersson T. Involvement of adenomatous polyposis coli (APC)/beta-catenin signalling in human breast cancer. Eur J Cancer 2000; 36:242-8.
    • (2000) Eur J Cancer , vol.36 , pp. 242-248
    • Jonsson, M.1    Borg, A.2    Nilbert, M.3    Andersson, T.4
  • 26
    • 0033119801 scopus 로고    scopus 로고
    • Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu O, McCormick F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999; 398:422-6.
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 27
    • 0030051927 scopus 로고    scopus 로고
    • No evidence for mutations in the alpha- and beta-catenin genes in human gastric and breast carcinomas
    • Candidus S, Bischoff P, Becker KF, Hofler H. No evidence for mutations in the alpha- and beta-catenin genes in human gastric and breast carcinomas. Cancer Res 1996; 56:49-52.
    • (1996) Cancer Res , vol.56 , pp. 49-52
    • Candidus, S.1    Bischoff, P.2    Becker, K.F.3    Hofler, H.4
  • 28
    • 0033923197 scopus 로고    scopus 로고
    • APC truncation and increased beta-catenin levels in a human breast cancer cell line
    • Schlosshauer PW, Brown SA, Eisinger K, et al. APC truncation and increased beta-catenin levels in a human breast cancer cell line. Carcinogenesis 2000; 21:1453-6.
    • (2000) Carcinogenesis , vol.21 , pp. 1453-1456
    • Schlosshauer, P.W.1    Brown, S.A.2    Eisinger, K.3
  • 29
    • 0036154011 scopus 로고    scopus 로고
    • Fibromatosis of the breast and mutations involving the APC/beta-catenin pathway
    • Abraham SC, Reynolds C, Lee JH, et al. Fibromatosis of the breast and mutations involving the APC/beta-catenin pathway. Hum Pathol 2002; 33:39-46.
    • (2002) Hum Pathol , vol.33 , pp. 39-46
    • Abraham, S.C.1    Reynolds, C.2    Lee, J.H.3
  • 30
    • 0032222643 scopus 로고    scopus 로고
    • Truncating somatic mutation in exon 15 of the APC gene is a rare event in human breast carcinomas. Mutations in brief no. 179
    • Online
    • Sorlie T, Bukholm I, Borresen-Dale AL. Truncating somatic mutation in exon 15 of the APC gene is a rare event in human breast carcinomas. Mutations in brief no. 179. Online. Hum Mutat 1998; 12:215.
    • (1998) Hum Mutat , vol.12 , pp. 215
    • Sorlie, T.1    Bukholm, I.2    Borresen-Dale, A.L.3
  • 31
    • 0033083827 scopus 로고    scopus 로고
    • Cloning of the human homolog of conductin (AXIN2), a gene mapping to chromosome 17q23-q24
    • Mai M, Qian C, Yokomizo A, Smith DI, Liu W. Cloning of the human homolog of conductin (AXIN2), a gene mapping to chromosome 17q23-q24. Genomics 1999; 55:341-4.
    • (1999) Genomics , vol.55 , pp. 341-344
    • Mai, M.1    Qian, C.2    Yokomizo, A.3    Smith, D.I.4    Liu, W.5
  • 32
    • 0033948526 scopus 로고    scopus 로고
    • Sequence variants of the axin gene in breast, colon, and other cancers: An analysis of mutations that interfere with GSK3 binding
    • Webster MT, Rozycka M, Sara E, et al. Sequence variants of the axin gene in breast, colon, and other cancers: an analysis of mutations that interfere with GSK3 binding. Genes Chromosomes Cancer 2000; 28:443-53.
    • (2000) Genes Chromosomes Cancer , vol.28 , pp. 443-453
    • Webster, M.T.1    Rozycka, M.2    Sara, E.3
  • 33
    • 0035902050 scopus 로고    scopus 로고
    • LDL-receptor-related protein 6 is a receptor for Dickkopf proteins
    • Mao B, Wu W, Li Y, et al. LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature 2001; 411:321-5.
    • (2001) Nature , vol.411 , pp. 321-325
    • Mao, B.1    Wu, W.2    Li, Y.3
  • 34
    • 18244427021 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway
    • Mao J, Wang J, Liu B, et al. Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol Cell 2001; 7:801-9.
    • (2001) Mol Cell , vol.7 , pp. 801-809
    • Mao, J.1    Wang, J.2    Liu, B.3
  • 35
    • 0037118285 scopus 로고    scopus 로고
    • High bone density due to a mutation in LDL-receptor-related protein 5
    • Boyden LM, Mao J, Belsky J, et al. High bone density due to a mutation in LDL-receptor-related protein 5. N Engl J Med 2002; 346:1513-21.
    • (2002) N Engl J Med , vol.346 , pp. 1513-1521
    • Boyden, L.M.1    Mao, J.2    Belsky, J.3
  • 36
    • 0028902359 scopus 로고
    • Wnt5a cloning, expression, and up-regulation in human primary breast cancers
    • Lejeune S, Huguet EL, Hamby A, Poulsom R, Harris AL. Wnt5a cloning, expression, and up-regulation in human primary breast cancers. Clin Cancer Res 1995; 1:215-22.
    • (1995) Clin Cancer Res , vol.1 , pp. 215-222
    • Lejeune, S.1    Huguet, E.L.2    Hamby, A.3    Poulsom, R.4    Harris, A.L.5
  • 37
    • 0037081290 scopus 로고    scopus 로고
    • Loss of Wnt-5a protein is associated with early relapse in invasive ductal breast carcinomas
    • Jonsson M, Dejmek J, Bendahl PO, Andersson T. Loss of Wnt-5a protein is associated with early relapse in invasive ductal breast carcinomas. Cancer Res 2002; 62:409-16.
    • (2002) Cancer Res , vol.62 , pp. 409-416
    • Jonsson, M.1    Dejmek, J.2    Bendahl, P.O.3    Andersson, T.4
  • 38
    • 0029096787 scopus 로고
    • Aberrant expression of the growth factor Wnt-5a in human malignancy
    • Iozzo RV, Eichstetter I, Danielson KG. Aberrant expression of the growth factor Wnt-5a in human malignancy. Cell Regulation 1995; 55:3495-9.
    • (1995) Cell Regulation , vol.55 , pp. 3495-3499
    • Iozzo, R.V.1    Eichstetter, I.2    Danielson, K.G.3
  • 39
    • 0029738843 scopus 로고    scopus 로고
    • Compartment switching of WNT-2 expression in human breast tumors
    • Dale TC, Weber-Hall SJ, Smith K, et al. Compartment switching of WNT-2 expression in human breast tumors. Cell Regulation 1996; 56:4320-3.
    • (1996) Cell Regulation , vol.56 , pp. 4320-4323
    • Dale, T.C.1    Weber-Hall, S.J.2    Smith, K.3
  • 40
    • 0035855667 scopus 로고    scopus 로고
    • WNT pathway and mammary carcinogenesis: Loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type
    • Ugolini F, Charafe-Jauffret E, Bardou VJ, et al. WNT pathway and mammary carcinogenesis: loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type. Oncogene 2001; 20:5810-7.
    • (2001) Oncogene , vol.20 , pp. 5810-5817
    • Ugolini, F.1    Charafe-Jauffret, E.2    Bardou, V.J.3
  • 41
    • 0141995804 scopus 로고    scopus 로고
    • WIF1, a component of the Wnt pathway, is down-regulated in prostate, breast, lung, and bladder cancer
    • Wissmann C, Wild PJ, Kaiser S, et al. WIF1, a component of the Wnt pathway, is down-regulated in prostate, breast, lung, and bladder cancer. J Pathol 2003; 201:204-12.
    • (2003) J Pathol , vol.201 , pp. 204-212
    • Wissmann, C.1    Wild, P.J.2    Kaiser, S.3
  • 42
    • 0030973456 scopus 로고    scopus 로고
    • Casein kinase 2 associates with and phosphorylates dishevelled
    • Willert K, Brink M, Wodarz A, Varmus H, Nusse R. Casein kinase 2 associates with and phosphorylates dishevelled. EMBO J 1997; 16:3089-96.
    • (1997) EMBO J , vol.16 , pp. 3089-3096
    • Willert, K.1    Brink, M.2    Wodarz, A.3    Varmus, H.4    Nusse, R.5
  • 43
    • 0038267245 scopus 로고    scopus 로고
    • CK2 phosphorylation of the armadillo repeat region of beta-catenin potentiates Wnt signaling
    • Song DH, Dominguez I, Mizuno J, Kaut M, Mohr SC, Seldin DC. CK2 phosphorylation of the armadillo repeat region of beta-catenin potentiates Wnt signaling. J Biol Chem 2003; 278:24018-25.
    • (2003) J Biol Chem , vol.278 , pp. 24018-24025
    • Song, D.H.1    Dominguez, I.2    Mizuno, J.3    Kaut, M.4    Mohr, S.C.5    Seldin, D.C.6
  • 45
    • 0037334895 scopus 로고    scopus 로고
    • One-thousand-and-one substrates of protein kinase CK2?
    • Meggio F, Pinna LA. One-thousand-and-one substrates of protein kinase CK2? Faseb J 2003;17:349-68.
    • (2003) Faseb J , vol.17 , pp. 349-368
    • Meggio, F.1    Pinna, L.A.2
  • 47
    • 0037195920 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 induces Lef/Tcf-dependent transcription in human endothelial cells
    • Holnthoner W, Pillinger M, Groger M, et al. Fibroblast growth factor-2 induces Lef/Tcf-dependent transcription in human endothelial cells. J Biol Chem 2002; 277:45847-53.
    • (2002) J Biol Chem , vol.277 , pp. 45847-45853
    • Holnthoner, W.1    Pillinger, M.2    Groger, M.3
  • 48
    • 0035907390 scopus 로고    scopus 로고
    • Akt participation in the Wnt signaling pathway through Dishevelled
    • Fukumoto S, Hsieh CM, Maemura K, et al. Akt participation in the Wnt signaling pathway through Dishevelled. J Biol Chem 2001; 276:17479-83.
    • (2001) J Biol Chem , vol.276 , pp. 17479-17483
    • Fukumoto, S.1    Hsieh, C.M.2    Maemura, K.3
  • 49
    • 0037163032 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase/Akt stimulates androgen pathway through GSK3beta inhibition and nuclear beta-catenin accumulation
    • Sharma M, Chuang WW, Sun Z. Phosphatidylinositol 3-kinase/Akt stimulates androgen pathway through GSK3beta inhibition and nuclear beta-catenin accumulation. J Biol Chem 2002; 277:30935-41.
    • (2002) J Biol Chem , vol.277 , pp. 30935-30941
    • Sharma, M.1    Chuang, W.W.2    Sun, Z.3
  • 50
    • 0035843148 scopus 로고    scopus 로고
    • Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation
    • Desbois-Mouthon C, Cadoret A, Blivet-Van Eggelpoel MJ, et al. Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation. Oncogene 2001; 20:252-9.
    • (2001) Oncogene , vol.20 , pp. 252-259
    • Desbois-Mouthon, C.1    Cadoret, A.2    Blivet-Van Eggelpoel, M.J.3
  • 51
    • 0032530482 scopus 로고    scopus 로고
    • Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase
    • USA
    • Delcommenne M, Tan C, Gray V, Rue L, Woodgett J, Dedhar S. Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase. Proc Natl Acad Sci USA 1998; 95:11211-6.
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 11211-11216
    • Delcommenne, M.1    Tan, C.2    Gray, V.3    Rue, L.4    Woodgett, J.5    Dedhar, S.6
  • 52
    • 0032516094 scopus 로고    scopus 로고
    • Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways
    • USA
    • Novak A, Hsu SC, Leung-Hagesteijn C, et al. Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways. Proc Natl Acad Sci USA 1998; 95:4374-9.
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 4374-4379
    • Novak, A.1    Hsu, S.C.2    Leung-Hagesteijn, C.3
  • 53
    • 84907115825 scopus 로고
    • Tyrosine phosphorylation of beta-catenin and plakoglobin enhanced by hepatocyte growth factor and epidermal growth factor in human carcinoma cells
    • Shibamoto S, Hayakawa M, Takeuchi K, et al. Tyrosine phosphorylation of beta-catenin and plakoglobin enhanced by hepatocyte growth factor and epidermal growth factor in human carcinoma cells. Cell Adhes Commun 1994; 1:295-305.
    • (1994) Cell Adhes Commun , vol.1 , pp. 295-305
    • Shibamoto, S.1    Hayakawa, M.2    Takeuchi, K.3
  • 54
    • 0028170977 scopus 로고
    • Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor
    • Hoschuetzky H, Aberle H, Kemler R. Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor. J Cell Biol 1994; 127:1375-80.
    • (1994) J Cell Biol , vol.127 , pp. 1375-1380
    • Hoschuetzky, H.1    Aberle, H.2    Kemler, R.3
  • 55
    • 0028987640 scopus 로고
    • C-erbB-2 gene product directly associates with beta-catenin and plakoglobin
    • Kanai Y, Ochiai A, Shibata T, et al. c-erbB-2 gene product directly associates with beta-catenin and plakoglobin. Biochem Biophys Res Commun 1995; 208:1067-72.
    • (1995) Biochem Biophys Res Commun , vol.208 , pp. 1067-1072
    • Kanai, Y.1    Ochiai, A.2    Shibata, T.3
  • 56
    • 0035958897 scopus 로고    scopus 로고
    • Tiam1 overexpression potentiates heregulin-induced lymphoid enhancer factor-1/beta -catenin nuclear signaling in breast cancer cells by modulating the intercellular stability
    • Adam L, Vadlamudi RK, McCrea P, Kumar R. Tiam1 overexpression potentiates heregulin-induced lymphoid enhancer factor-1/beta -catenin nuclear signaling in breast cancer cells by modulating the intercellular stability. J Biol Chem 2001; 276:28443-50.
    • (2001) J Biol Chem , vol.276 , pp. 28443-28450
    • Adam, L.1    Vadlamudi, R.K.2    McCrea, P.3    Kumar, R.4
  • 57
    • 0037151060 scopus 로고    scopus 로고
    • ErbB-beta-catenin complexes are associated with human infiltrating ductal breast and murine mammary tumor virus (MMTV)-Wnt-1 and MMTV-c-Neu transgenic carcinomas
    • Schroeder JA, Adriance MC, McConnell EJ, Thompson MC, Pockaj B, Gendler SJ. ErbB-beta-catenin complexes are associated with human infiltrating ductal breast and murine mammary tumor virus (MMTV)-Wnt-1 and MMTV-c-Neu transgenic carcinomas. J Biol Chem 2002; 277:22692-8.
    • (2002) J Biol Chem , vol.277 , pp. 22692-22698
    • Schroeder, J.A.1    Adriance, M.C.2    McConnell, E.J.3    Thompson, M.C.4    Pockaj, B.5    Gendler, S.J.6
  • 58
    • 0034710915 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin
    • USA
    • Playford MP, Bicknell D, Bodmer WF, Macaulay VM. Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin. Proc Natl Acad Sci USA 2000; 97:12103-8.
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 12103-12108
    • Playford, M.P.1    Bicknell, D.2    Bodmer, W.F.3    Macaulay, V.M.4
  • 59
    • 0034987934 scopus 로고    scopus 로고
    • Tyrosine phosphorylation translocates beta-catenin from cell→cell interface to the cytoplasm, but does not significantly enhance the LEF-1-dependent transactivating function
    • Kim K, Lee KY. Tyrosine phosphorylation translocates beta-catenin from cell→cell interface to the cytoplasm, but does not significantly enhance the LEF-1-dependent transactivating function. Cell Biol Int 2001; 25:421-7.
    • (2001) Cell Biol Int , vol.25 , pp. 421-427
    • Kim, K.1    Lee, K.Y.2
  • 60
  • 61
    • 1642421130 scopus 로고    scopus 로고
    • Target-based agents against ErbB receptors and their ligands: A novel approach to cancer treatment
    • Normanno N, Bianco C, De Luca A, Maiello MR, Salomon DS. Target-based agents against ErbB receptors and their ligands: a novel approach to cancer treatment. Endocr Relat Cancer 2003;10:1-21.
    • (2003) Endocr Relat Cancer , vol.10 , pp. 1-21
    • Normanno, N.1    Bianco, C.2    De Luca, A.3    Maiello, M.R.4    Salomon, D.S.5
  • 62
    • 0037010076 scopus 로고    scopus 로고
    • Overview of epidermal growth factor receptor biology and its role as a therapeutic target in human neoplasia
    • Arteaga CL. Overview of epidermal growth factor receptor biology and its role as a therapeutic target in human neoplasia. Semin Oncol 2002; 29:3-9.
    • (2002) Semin Oncol , vol.29 , pp. 3-9
    • Arteaga, C.L.1
  • 63
    • 0035721657 scopus 로고    scopus 로고
    • PTEN deficiency: A role in mammary carcinogenesis
    • Petrocelli T, Slingerland JM. PTEN deficiency: a role in mammary carcinogenesis. Breast Cancer Res 2001; 3:356-60.
    • (2001) Breast Cancer Res , vol.3 , pp. 356-360
    • Petrocelli, T.1    Slingerland, J.M.2
  • 64
    • 0035844886 scopus 로고    scopus 로고
    • Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation
    • Persad S, Troussard AA, McPhee TR, Mulholland DJ, Dedhar S. Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation. J Cell Biol 2001; 153:1161-74.
    • (2001) J Cell Biol , vol.153 , pp. 1161-1174
    • Persad, S.1    Troussard, A.A.2    McPhee, T.R.3    Mulholland, D.J.4    Dedhar, S.5
  • 65
    • 0037031934 scopus 로고    scopus 로고
    • Fibroblast growth factor 1 regulates signaling via the glycogen synthase kinase-3beta pathway. Implications for neuroprotection
    • Hashimoto M, Sagara Y, Langford D, et al. Fibroblast growth factor 1 regulates signaling via the glycogen synthase kinase-3beta pathway. Implications for neuroprotection. J Biol Chem 2002; 277:32985-91.
    • (2002) J Biol Chem , vol.277 , pp. 32985-32991
    • Hashimoto, M.1    Sagara, Y.2    Langford, D.3
  • 66
    • 0037221767 scopus 로고    scopus 로고
    • TP53 and breast cancer
    • Borresen-Dale AL. TP53 and breast cancer. Hum Mutat 2003;21:292-300.
    • (2003) Hum Mutat , vol.21 , pp. 292-300
    • Borresen-Dale, A.L.1
  • 67
    • 0033151867 scopus 로고    scopus 로고
    • Excess beta-catenin promotes accumulation of transcriptionally active p53
    • Damalas A, Ben-Ze'ev A, Simcha I, et al. Excess beta-catenin promotes accumulation of transcriptionally active p53. EMBO J 1999; 18:3054-63.
    • (1999) EMBO J , vol.18 , pp. 3054-3063
    • Damalas, A.1    Ben-Ze'ev, A.2    Simcha, I.3
  • 68
    • 0035947080 scopus 로고    scopus 로고
    • Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses
    • Matsuzawa SI, Reed JC. Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses. Mol Cell 2001; 7:915-26.
    • (2001) Mol Cell , vol.7 , pp. 915-926
    • Matsuzawa, S.I.1    Reed, J.C.2
  • 69
    • 0035947083 scopus 로고    scopus 로고
    • Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein
    • Liu J, Stevens J, Rote CA, et al. Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein. Mol Cell 2001;7:927-36.
    • (2001) Mol Cell , vol.7 , pp. 927-936
    • Liu, J.1    Stevens, J.2    Rote, C.A.3
  • 70
    • 0034808019 scopus 로고    scopus 로고
    • Down-regulation of beta-catenin by activated p53
    • Sadot E, Geiger B, Oren M, Ben-Ze'ev A. Down-regulation of beta-catenin by activated p53. Mol Cell Biol 2001; 21:6768-81.
    • (2001) Mol Cell Biol , vol.21 , pp. 6768-6781
    • Sadot, E.1    Geiger, B.2    Oren, M.3    Ben-Ze'ev, A.4
  • 71
    • 0035796405 scopus 로고    scopus 로고
    • Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1
    • Wulf GM, Ryo A, Wulf GG, et al. Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1. EMBO J 2001; 20:3459-72.
    • (2001) EMBO J , vol.20 , pp. 3459-3472
    • Wulf, G.M.1    Ryo, A.2    Wulf, G.G.3
  • 72
    • 0035513435 scopus 로고    scopus 로고
    • Frequent up-regulation of WNT2 in primary gastric cancer and colorectal cancer
    • Katoh M. Frequent up-regulation of WNT2 in primary gastric cancer and colorectal cancer. Int J Oncol 2001; 19:1003-7.
    • (2001) Int J Oncol , vol.19 , pp. 1003-1007
    • Katoh, M.1
  • 73
    • 0028272485 scopus 로고
    • Differential expression of human Wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and diseased breast tissue
    • Huguet EL, McMahon JA, McMahon AP, Bicknell R, Harris AL. Differential expression of human Wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and diseased breast tissue. Cancer Res 1994; 54:2615-21.
    • (1994) Cancer Res , vol.54 , pp. 2615-2621
    • Huguet, E.L.1    McMahon, J.A.2    McMahon, A.P.3    Bicknell, R.4    Harris, A.L.5
  • 74
    • 0030899334 scopus 로고    scopus 로고
    • A novel human Wnt gene, WNT10B, maps to 12q13 and is expressed in human breast carcinomas
    • Bui TD, Rankin J, Smith K, et al. A novel human Wnt gene, WNT10B, maps to 12q13 and is expressed in human breast carcinomas. Oncogene 1997; 14:1249-53.
    • (1997) Oncogene , vol.14 , pp. 1249-1253
    • Bui, T.D.1    Rankin, J.2    Smith, K.3
  • 75
    • 0032833946 scopus 로고    scopus 로고
    • Reduced expression of APC and DCC gene protein in breast cancer
    • Ho KY, Kalle WH, Lo TH, Lam WY, Tang CM. Reduced expression of APC and DCC gene protein in breast cancer. Histopathology 1999; 35:249-56.
    • (1999) Histopathology , vol.35 , pp. 249-256
    • Ho, K.Y.1    Kalle, W.H.2    Lo, T.H.3    Lam, W.Y.4    Tang, C.M.5
  • 76
    • 0036207721 scopus 로고    scopus 로고
    • The Wnt pathway, epithelial-stromal interactions, and malignant progression in phyllodes tumours
    • Sawyer EJ, Hanby AM, Rowan AJ, et al. The Wnt pathway, epithelial-stromal interactions, and malignant progression in phyllodes tumours. J Pathol 2002;196:437-44.
    • (2002) J Pathol , vol.196 , pp. 437-444
    • Sawyer, E.J.1    Hanby, A.M.2    Rowan, A.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.