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Volumn 42, Issue SUPPL. 2, 2005, Pages

Decitabine in chronic leukemias

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ALPHA1 INTERFERON; AZACITIDINE; BUSULFAN; CHLORAMBUCIL; CYCLOPHOSPHAMIDE; CYTOSINE DERIVATIVE; FLUDARABINE; HISTONE DEACETYLASE INHIBITOR; IMATINIB; PROTEIN TYROSINE KINASE INHIBITOR; PURINE DERIVATIVE; PYRIMIDINE DERIVATIVE; RETINOIC ACID; RITUXIMAB; VALPROIC ACID;

EID: 21844443820     PISSN: 00371963     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.seminhematol.2005.05.005     Document Type: Article
Times cited : (18)

References (67)
  • 1
    • 0024240878 scopus 로고
    • Regimen-related toxicity in patients undergoing bone marrow transplantation
    • S.I. Bearman, F.R. Appelbaum, C.D. Buckner Regimen-related toxicity in patients undergoing bone marrow transplantation J Clin Oncol 6 1988 1562 1568
    • (1988) J Clin Oncol , vol.6 , pp. 1562-1568
    • Bearman, S.I.1    Appelbaum, F.R.2    Buckner, C.D.3
  • 2
    • 0017715217 scopus 로고
    • Investigation of a new parameter in chronic lymphocytic leukemia: The percentage of large peripheral lymphocytes determined by the Hemalog D. Prognostic significance
    • J.L. Binet, G. Vaugier, G. Dighiero Investigation of a new parameter in chronic lymphocytic leukemia The percentage of large peripheral lymphocytes determined by the Hemalog D. Prognostic significance Am J Med 63 1977 683 688
    • (1977) Am J Med , vol.63 , pp. 683-688
    • Binet, J.L.1    Vaugier, G.2    Dighiero, G.3
  • 3
    • 10744232328 scopus 로고    scopus 로고
    • Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis
    • S. Branford, Z. Rudzki, S. Walsh Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis Blood 102 2003 276 283
    • (2003) Blood , vol.102 , pp. 276-283
    • Branford, S.1    Rudzki, Z.2    Walsh, S.3
  • 5
    • 19944429446 scopus 로고    scopus 로고
    • Addition of rituximab to fludarabine may prolong progression-free survival and overall survival in patients with previously untreated chronic lymphocytic leukemia: An updated retrospective, comparative analysis of CALGB 9712 and CALGB 9011
    • J.C. Byrd, K. Rai, B.L. Peterson Addition of rituximab to fludarabine may prolong progression-free survival and overall survival in patients with previously untreated chronic lymphocytic leukemia An updated retrospective, comparative analysis of CALGB 9712 and CALGB 9011 Blood 105 2005 49 53
    • (2005) Blood , vol.105 , pp. 49-53
    • Byrd, J.C.1    Rai, K.2    Peterson, B.L.3
  • 6
    • 0029981025 scopus 로고    scopus 로고
    • National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: Revised guidelines for diagnosis and treatment
    • B.D. Cheson, J.M. Bennett, M. Grever National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia Revised guidelines for diagnosis and treatment Blood 87 1996 4990 4997
    • (1996) Blood , vol.87 , pp. 4990-4997
    • Cheson, B.D.1    Bennett, J.M.2    Grever, M.3
  • 7
    • 0037255947 scopus 로고    scopus 로고
    • Advanced-phase chronic myeloid leukemia
    • J. Cortes, H. Kantarjian Advanced-phase chronic myeloid leukemia Semin Hematol 40 2003 79 86
    • (2003) Semin Hematol , vol.40 , pp. 79-86
    • Cortes, J.1    Kantarjian, H.2
  • 9
    • 0031594270 scopus 로고    scopus 로고
    • Hypermethylation of the M27beta (DXS255) locus in chronic B-cell leukaemia
    • P.E. Crossen, M.J. Morrison Hypermethylation of the M27beta (DXS255) locus in chronic B-cell leukaemia Br J Haematol 100 1998 191 193
    • (1998) Br J Haematol , vol.100 , pp. 191-193
    • Crossen, P.E.1    Morrison, M.J.2
  • 10
    • 0344211845 scopus 로고    scopus 로고
    • Long-term follow-up of a phase I study of high-dose decitabine, busulfan, and cyclophosphamide plus allogeneic transplantation for the treatment of patients with leukemias
    • M. de Lima, F. Ravandi, M. Shahjahan Long-term follow-up of a phase I study of high-dose decitabine, busulfan, and cyclophosphamide plus allogeneic transplantation for the treatment of patients with leukemias Cancer 97 2003 1242 1247
    • (2003) Cancer , vol.97 , pp. 1242-1247
    • De Lima, M.1    Ravandi, F.2    Shahjahan, M.3
  • 11
    • 0034670036 scopus 로고    scopus 로고
    • The molecular biology of chronic myeloid leukemia
    • M.W. Deininger, J.M. Goldman, J.V. Melo The molecular biology of chronic myeloid leukemia Blood 96 2000 3343 3356
    • (2000) Blood , vol.96 , pp. 3343-3356
    • Deininger, M.W.1    Goldman, J.M.2    Melo, J.V.3
  • 12
    • 0033572883 scopus 로고    scopus 로고
    • The American College of Surgeons Commission on Cancer and the American Cancer Society. the National Cancer Data Base report on age, gender, treatment, and outcomes of patients with chronic lymphocytic leukemia
    • L.F. Diehl, L.H. Karnell, H.R. Menck The American College of Surgeons Commission on Cancer and the American Cancer Society. The National Cancer Data Base report on age, gender, treatment, and outcomes of patients with chronic lymphocytic leukemia Cancer 86 1999 2684 2692
    • (1999) Cancer , vol.86 , pp. 2684-2692
    • Diehl, L.F.1    Karnell, L.H.2    Menck, H.R.3
  • 13
    • 0034727833 scopus 로고    scopus 로고
    • Genomic aberrations and survival in chronic lymphocytic leukemia
    • H. Dohner, S. Stilgenbauer, A. Benner Genomic aberrations and survival in chronic lymphocytic leukemia N Engl J Med 343 2000 1910 1916
    • (2000) N Engl J Med , vol.343 , pp. 1910-1916
    • Dohner, H.1    Stilgenbauer, S.2    Benner, A.3
  • 14
    • 0036463948 scopus 로고    scopus 로고
    • Perspectives on the development of a molecularly targeted agent
    • B.J. Druker Perspectives on the development of a molecularly targeted agent Cancer Cell 1 2002 31 36
    • (2002) Cancer Cell , vol.1 , pp. 31-36
    • Druker, B.J.1
  • 15
    • 32644484164 scopus 로고    scopus 로고
    • Fludarabine and cyclophosphamide produces a higher remission rates and longer progression free survival (PFS) than fludarabine (F) alone in first line therapy of advanced chronic lymphocytic leukemia (CLL): Results of a phase II (CLL4 Protocol) of the German CLL Study Group (GCLLSG)
    • B.F. Eichhorst, G. Hopfinger, R. Pasold Fludarabine and cyclophosphamide produces a higher remission rates and longer progression free survival (PFS) than fludarabine (F) alone in first line therapy of advanced chronic lymphocytic leukemia (CLL) Results of a phase II (CLL4 Protocol) of the German CLL Study Group (GCLLSG) Blood 104 2004 102 (abstr)
    • (2004) Blood , vol.104 , pp. 102
    • Eichhorst, B.F.1    Hopfinger, G.2    Pasold, R.3
  • 16
    • 0032999728 scopus 로고    scopus 로고
    • Chronic myelogenous leukemia: Update on biology and treatment
    • S. Faderl, H.M. Kantarjian, M. Talpaz Chronic myelogenous leukemia Update on biology and treatment Oncology (Huntingt) 13 1999 169 180
    • (1999) Oncology (Huntingt) , vol.13 , pp. 169-180
    • Faderl, S.1    Kantarjian, H.M.2    Talpaz, M.3
  • 17
    • 26044450179 scopus 로고    scopus 로고
    • Fludarabine and cyclophosphamide produces a higher complete response rate and more durabel remissions than fludarabine in patients with previously untreated CLL: Intergroup Trial E2997
    • I.W. Flinn, M. Grever, D. Neuberg Fludarabine and cyclophosphamide produces a higher complete response rate and more durabel remissions than fludarabine in patients with previously untreated CLL Intergroup Trial E2997 Blood 104 2004 475 (abstr)
    • (2004) Blood , vol.104 , pp. 475
    • Flinn, I.W.1    Grever, M.2    Neuberg, D.3
  • 18
    • 0030946652 scopus 로고    scopus 로고
    • Studies of decitabine with allogeneic progenitor cell transplantation
    • S. Giralt, M. Davis, S. O'Brien Studies of decitabine with allogeneic progenitor cell transplantation Leukemia 11 suppl 1 1997 S32 S34
    • (1997) Leukemia , vol.11 , Issue.1 SUPPL.
    • Giralt, S.1    Davis, M.2    O'Brien, S.3
  • 19
    • 0036014978 scopus 로고    scopus 로고
    • Molecular mechanisms of resistance to STI571 in chronic myeloid leukemia
    • M.E. Gorre, C.L. Sawyers Molecular mechanisms of resistance to STI571 in chronic myeloid leukemia Curr Opin Hematol 9 2002 303 307
    • (2002) Curr Opin Hematol , vol.9 , pp. 303-307
    • Gorre, M.E.1    Sawyers, C.L.2
  • 20
    • 0024216099 scopus 로고
    • Fludarabine monophosphate: A potentially useful agent in chronic lymphocytic leukemia
    • M.R. Grever, K.J. Kopecky, C.A. Coltman Fludarabine monophosphate A potentially useful agent in chronic lymphocytic leukemia Nouv Rev Fr Hematol 30 1988 457 459
    • (1988) Nouv Rev Fr Hematol , vol.30 , pp. 457-459
    • Grever, M.R.1    Kopecky, K.J.2    Coltman, C.A.3
  • 21
    • 0027239823 scopus 로고
    • Bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia
    • M. Hanada, D. Delia, A. Aiello bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia Blood 82 1993 1820 1828
    • (1993) Blood , vol.82 , pp. 1820-1828
    • Hanada, M.1    Delia, D.2    Aiello, A.3
  • 22
    • 0028072991 scopus 로고
    • Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma
    • J.G. Herman, F. Latif, Y. Weng Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma Proc Natl Acad Sci U S A 91 1994 9700 9704
    • (1994) Proc Natl Acad Sci U S a , vol.91 , pp. 9700-9704
    • Herman, J.G.1    Latif, F.2    Weng, Y.3
  • 23
    • 3242816121 scopus 로고    scopus 로고
    • Clinical resistance to imatinib: Mechanisms and implications
    • A. Hochhaus, T. Hughes Clinical resistance to imatinib Mechanisms and implications Hematol Oncol Clin North Am 18 2004 641 656
    • (2004) Hematol Oncol Clin North Am , vol.18 , pp. 641-656
    • Hochhaus, A.1    Hughes, T.2
  • 24
    • 10744229080 scopus 로고    scopus 로고
    • Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemia
    • T.P. Hughes, J. Kaeda, S. Branford Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemia N Engl J Med 349 2003 1423 1432
    • (2003) N Engl J Med , vol.349 , pp. 1423-1432
    • Hughes, T.P.1    Kaeda, J.2    Branford, S.3
  • 25
    • 10744233452 scopus 로고    scopus 로고
    • Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2′-deoxycytidine (decitabine) in hematopoietic malignancies
    • J.P. Issa, G. Garcia-Manero, F.J. Giles Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2′- deoxycytidine (decitabine) in hematopoietic malignancies Blood 103 2004 1635 1640
    • (2004) Blood , vol.103 , pp. 1635-1640
    • Issa, J.P.1    Garcia-Manero, G.2    Giles, F.J.3
  • 26
    • 21244431605 scopus 로고    scopus 로고
    • Phase II study of low-dose decitabine in patients with chronic myelogenous leukemia resistant to imatinib mesylate
    • J.P. Issa, V. Gharibyan, J. Cortes Phase II study of low-dose decitabine in patients with chronic myelogenous leukemia resistant to imatinib mesylate J Clin Oncol 2005 May 9, (Epub ahead of print)
    • (2005) J Clin Oncol
    • Issa, J.P.1    Gharibyan, V.2    Cortes, J.3
  • 29
    • 15844368449 scopus 로고    scopus 로고
    • Multicentre prospective randomised trial of fludarabine versus cyclophosphamide, doxorubicin, and prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia. the French Cooperative Group on CLL
    • S. Johnson, A.G. Smith, H. Loffler Multicentre prospective randomised trial of fludarabine versus cyclophosphamide, doxorubicin, and prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia. The French Cooperative Group on CLL Lancet 347 1996 1432 1438
    • (1996) Lancet , vol.347 , pp. 1432-1438
    • Johnson, S.1    Smith, A.G.2    Loffler, H.3
  • 30
    • 16944363756 scopus 로고    scopus 로고
    • Results of decitabine therapy in the accelerated and blastic phases of chronic myelogenous leukemia
    • H.M. Kantarjian, S.M. O'Brien, M. Keating Results of decitabine therapy in the accelerated and blastic phases of chronic myelogenous leukemia Leukemia 11 1997 1617 1620
    • (1997) Leukemia , vol.11 , pp. 1617-1620
    • Kantarjian, H.M.1    O'Brien, S.M.2    Keating, M.3
  • 31
    • 0037092980 scopus 로고    scopus 로고
    • Imatinib mesylate (STI571) therapy for Philadelphia chromosome-positive chronic myelogenous leukemia in blast phase
    • H.M. Kantarjian, J. Cortes, S. O'Brien Imatinib mesylate (STI571) therapy for Philadelphia chromosome-positive chronic myelogenous leukemia in blast phase Blood 99 2002 3547 3553
    • (2002) Blood , vol.99 , pp. 3547-3553
    • Kantarjian, H.M.1    Cortes, J.2    O'Brien, S.3
  • 32
    • 0037962005 scopus 로고    scopus 로고
    • Results of decitabine (5-aza-2′deoxycytidine) therapy in 130 patients with chronic myelogenous leukemia
    • H.M. Kantarjian, S. O'Brien, J. Cortes Results of decitabine (5-aza-2′deoxycytidine) therapy in 130 patients with chronic myelogenous leukemia Cancer 98 2003 522 528
    • (2003) Cancer , vol.98 , pp. 522-528
    • Kantarjian, H.M.1    O'Brien, S.2    Cortes, J.3
  • 33
    • 11144354274 scopus 로고    scopus 로고
    • High-dose imatinib mesylate therapy in newly diagnosed Philadelphia chromosome-positive chronic phase chronic myeloid leukemia
    • H. Kantarjian, M. Talpaz, S. O'Brien High-dose imatinib mesylate therapy in newly diagnosed Philadelphia chromosome-positive chronic phase chronic myeloid leukemia Blood 103 2004 2873 2878
    • (2004) Blood , vol.103 , pp. 2873-2878
    • Kantarjian, H.1    Talpaz, M.2    O'Brien, S.3
  • 34
    • 0030722392 scopus 로고    scopus 로고
    • Altered methylation of the human MDR1 promoter is associated with acquired multidrug resistance
    • P. Kantharidis, A. El-Osta, M. deSilva Altered methylation of the human MDR1 promoter is associated with acquired multidrug resistance Clin Cancer Res 3 1997 2025 2032
    • (1997) Clin Cancer Res , vol.3 , pp. 2025-2032
    • Kantharidis, P.1    El-Osta, A.2    Desilva, M.3
  • 35
    • 0024319910 scopus 로고
    • Fludarabine: A new agent with major activity against chronic lymphocytic leukemia
    • M.J. Keating, H. Kantarjian, M. Talpaz Fludarabine A new agent with major activity against chronic lymphocytic leukemia Blood 74 1989 19 25
    • (1989) Blood , vol.74 , pp. 19-25
    • Keating, M.J.1    Kantarjian, H.2    Talpaz, M.3
  • 36
    • 23044510136 scopus 로고    scopus 로고
    • Early results of a chemoimmunotherapy regimen of fludarabine, cyclophosphamide, and rituximab as initial therapy for chronic lymphocytic leukemia
    • M. Keating, S. O'Brien, M. Albitar Early results of a chemoimmunotherapy regimen of fludarabine, cyclophosphamide, and rituximab as initial therapy for chronic lymphocytic leukemia J Clin Oncol 2005 March 14, (Epub ahead of print)
    • (2005) J Clin Oncol
    • Keating, M.1    O'Brien, S.2    Albitar, M.3
  • 38
    • 0033766291 scopus 로고    scopus 로고
    • Human Dermo-1 has attributes similar to twist in early bone development
    • M.S. Lee, G. Lowe, S. Flanagan Human Dermo-1 has attributes similar to twist in early bone development Bone 27 2000 591 602
    • (2000) Bone , vol.27 , pp. 591-602
    • Lee, M.S.1    Lowe, G.2    Flanagan, S.3
  • 39
    • 0035889147 scopus 로고    scopus 로고
    • Randomized comparison of fludarabine, CAP, and ChOP in 938 previously untreated stage B and C chronic lymphocytic leukemia patients
    • M. Leporrier, S. Chevret, B. Cazin Randomized comparison of fludarabine, CAP, and ChOP in 938 previously untreated stage B and C chronic lymphocytic leukemia patients Blood 98 2001 2319 2325
    • (2001) Blood , vol.98 , pp. 2319-2325
    • Leporrier, M.1    Chevret, S.2    Cazin, B.3
  • 40
    • 0037103272 scopus 로고    scopus 로고
    • Relationship between p53 dysfunction, CD38 expression, and IgV(H) mutation in chronic lymphocytic leukemia
    • K. Lin, P.D. Sherrington, M. Dennis Relationship between p53 dysfunction, CD38 expression, and IgV(H) mutation in chronic lymphocytic leukemia Blood 100 2002 1404 1409
    • (2002) Blood , vol.100 , pp. 1404-1409
    • Lin, K.1    Sherrington, P.D.2    Dennis, M.3
  • 41
    • 0042744704 scopus 로고    scopus 로고
    • High frequency of p53 dysfunction and low level of VH mutation in chronic lymphocytic leukemia patients using the VH3-21 gene segment
    • K. Lin, S. Manocha, R.J. Harris High frequency of p53 dysfunction and low level of VH mutation in chronic lymphocytic leukemia patients using the VH3-21 gene segment Blood 102 2003 1145 1146
    • (2003) Blood , vol.102 , pp. 1145-1146
    • Lin, K.1    Manocha, S.2    Harris, R.J.3
  • 42
    • 0024272160 scopus 로고
    • Hypomethylation of ornithine decarboxylase gene and erb-A1 oncogene in human chronic lymphatic leukemia
    • V. Lipsanen, P. Leinonen, L. Alhonen Hypomethylation of ornithine decarboxylase gene and erb-A1 oncogene in human chronic lymphatic leukemia Blood 72 1988 2042 2044
    • (1988) Blood , vol.72 , pp. 2042-2044
    • Lipsanen, V.1    Leinonen, P.2    Alhonen, L.3
  • 43
    • 0033200349 scopus 로고    scopus 로고
    • Twist is a potential oncogene that inhibits apoptosis
    • R. Maestro, A.P. Dei Tos, Y. Hamamori Twist is a potential oncogene that inhibits apoptosis Genes Dev 13 1999 2207 2217
    • (1999) Genes Dev , vol.13 , pp. 2207-2217
    • Maestro, R.1    Dei Tos, A.P.2    Hamamori, Y.3
  • 44
    • 0034657952 scopus 로고    scopus 로고
    • Hypermethylation of E-cadherin in leukemia
    • J.R. Melki, P.C. Vincent, R.D. Brown Hypermethylation of E-cadherin in leukemia Blood 95 2000 3208 3213
    • (2000) Blood , vol.95 , pp. 3208-3213
    • Melki, J.R.1    Vincent, P.C.2    Brown, R.D.3
  • 45
    • 0022404250 scopus 로고
    • Induction of differentiation and inhibition of DNA methylation in HL-60 myeloid leukemic cells by 5-AZA-2′-deoxycytidine
    • R.L. Momparler, J. Bouchard, J. Samson Induction of differentiation and inhibition of DNA methylation in HL-60 myeloid leukemic cells by 5-AZA-2′-deoxycytidine Leuk Res 9 1985 1361 1366
    • (1985) Leuk Res , vol.9 , pp. 1361-1366
    • Momparler, R.L.1    Bouchard, J.2    Samson, J.3
  • 46
    • 10744233716 scopus 로고    scopus 로고
    • Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
    • S.G. O'Brien, F. Guilhot, R.A. Larson Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia N Engl J Med 348 2003 994 1004
    • (2003) N Engl J Med , vol.348 , pp. 994-1004
    • O'Brien, S.G.1    Guilhot, F.2    Larson, R.A.3
  • 47
    • 32644481446 scopus 로고    scopus 로고
    • Zap70 methylation correlates with Zap70 expression in chronic lymphocytic leukemia
    • D.G. Oscier, Z. Davis, W. Michaela Zap70 methylation correlates with Zap70 expression in chronic lymphocytic leukemia Blood 104 2004 962 (abstr)
    • (2004) Blood , vol.104 , pp. 962
    • Oscier, D.G.1    Davis, Z.2    Michaela, W.3
  • 48
    • 0028787221 scopus 로고
    • CDKN2 gene silencing in lung cancer by DNA hypermethylation and kinetics of p16INK4 protein induction by 5-aza 2′deoxycytidine
    • G.A. Otterson, S.N. Khleif, W. Chen CDKN2 gene silencing in lung cancer by DNA hypermethylation and kinetics of p16INK4 protein induction by 5-aza 2′deoxycytidine Oncogene 11 1995 1211 1216
    • (1995) Oncogene , vol.11 , pp. 1211-1216
    • Otterson, G.A.1    Khleif, S.N.2    Chen, W.3
  • 49
    • 0037434853 scopus 로고    scopus 로고
    • Imatinib mesylate - The new gold standard for treatment of chronic myeloid leukemia
    • K. Peggs, S. Mackinnon Imatinib mesylate - The new gold standard for treatment of chronic myeloid leukemia N Engl J Med 348 2003 1048 1050
    • (2003) N Engl J Med , vol.348 , pp. 1048-1050
    • Peggs, K.1    MacKinnon, S.2
  • 50
    • 0021160287 scopus 로고
    • 5-Aza-2′-deoxycytidine induces terminal differentiation of leukemic blasts from patients with acute myeloid leukemias
    • A. Pinto, V. Attadia, A. Fusco 5-Aza-2′-deoxycytidine induces terminal differentiation of leukemic blasts from patients with acute myeloid leukemias Blood 64 1984 922 929
    • (1984) Blood , vol.64 , pp. 922-929
    • Pinto, A.1    Attadia, V.2    Fusco, A.3
  • 51
    • 0016740933 scopus 로고
    • Clinical staging of chronic lymphocytic leukemia
    • K.R. Rai, A. Sawitsky, E.P. Cronkite Clinical staging of chronic lymphocytic leukemia Blood 46 1975 219 234
    • (1975) Blood , vol.46 , pp. 219-234
    • Rai, K.R.1    Sawitsky, A.2    Cronkite, E.P.3
  • 52
    • 0034649696 scopus 로고    scopus 로고
    • Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia
    • K.R. Rai, B.L. Peterson, F.R. Appelbaum Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia N Engl J Med 343 2000 1750 1757
    • (2000) N Engl J Med , vol.343 , pp. 1750-1757
    • Rai, K.R.1    Peterson, B.L.2    Appelbaum, F.R.3
  • 53
    • 21244503530 scopus 로고    scopus 로고
    • TWIST2 demonstrates differential methylation in immunoglobulin variable heavy chain mutated and unmutated chronic lymphocytic leukemia
    • A. Raval, D.M. Lucas, J.J. Matkovic TWIST2 demonstrates differential methylation in immunoglobulin variable heavy chain mutated and unmutated chronic lymphocytic leukemia J Clin Oncol 2005 April 4, (Epub ahead of print)
    • (2005) J Clin Oncol
    • Raval, A.1    Lucas, D.M.2    Matkovic, J.J.3
  • 54
    • 0034940793 scopus 로고    scopus 로고
    • Decitabine with allogeneic peripheral blood stem cell transplantation in the therapy of leukemia relapse following a prior transplant: Results of a phase I study
    • F. Ravandi, H. Kantarjian, A. Cohen Decitabine with allogeneic peripheral blood stem cell transplantation in the therapy of leukemia relapse following a prior transplant Results of a phase I study Bone Marrow Transplant 27 2001 1221 1225
    • (2001) Bone Marrow Transplant , vol.27 , pp. 1221-1225
    • Ravandi, F.1    Kantarjian, H.2    Cohen, A.3
  • 55
    • 0037044560 scopus 로고    scopus 로고
    • Alterations of DNA methylation in hematologic malignancies
    • L.J. Rush, C. Plass Alterations of DNA methylation in hematologic malignancies Cancer Lett 185 2002 1 12
    • (2002) Cancer Lett , vol.185 , pp. 1-12
    • Rush, L.J.1    Plass, C.2
  • 56
    • 11144356462 scopus 로고    scopus 로고
    • Epigenetic profiling in chronic lymphocytic leukemia reveals novel methylation targets
    • L.J. Rush, A. Raval, P. Funchain Epigenetic profiling in chronic lymphocytic leukemia reveals novel methylation targets Cancer Res 64 2004 2424 2433
    • (2004) Cancer Res , vol.64 , pp. 2424-2433
    • Rush, L.J.1    Raval, A.2    Funchain, P.3
  • 57
    • 0033572876 scopus 로고    scopus 로고
    • Chronic myelogenous leukemia in nonlymphoid blastic phase: Analysis of the results of first salvage therapy with three different treatment approaches for 162 patients
    • S. Sacchi, H.M. Kantarjian, S. O'Brien Chronic myelogenous leukemia in nonlymphoid blastic phase Analysis of the results of first salvage therapy with three different treatment approaches for 162 patients Cancer 86 1999 2632 2641
    • (1999) Cancer , vol.86 , pp. 2632-2641
    • Sacchi, S.1    Kantarjian, H.M.2    O'Brien, S.3
  • 58
    • 0035799382 scopus 로고    scopus 로고
    • Changes in DNA methylation in neoplasia: Pathophysiology and therapeutic implications
    • V. Santini, H.M. Kantarjian, J.P. Issa Changes in DNA methylation in neoplasia pathophysiology and therapeutic implications Ann Intern Med 134 2001 573 586
    • (2001) Ann Intern Med , vol.134 , pp. 573-586
    • Santini, V.1    Kantarjian, H.M.2    Issa, J.P.3
  • 59
    • 0037093092 scopus 로고    scopus 로고
    • Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: Results of a phase II study
    • C.L. Sawyers, A. Hochhaus, E. Feldman Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis Results of a phase II study Blood 99 2002 3530 3539
    • (2002) Blood , vol.99 , pp. 3530-3539
    • Sawyers, C.L.1    Hochhaus, A.2    Feldman, E.3
  • 60
    • 0001686739 scopus 로고    scopus 로고
    • Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia
    • N.P. Shah, J.M. Nicoll, B. Nagar Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia Cancer Cell 2 2002 117 125
    • (2002) Cancer Cell , vol.2 , pp. 117-125
    • Shah, N.P.1    Nicoll, J.M.2    Nagar, B.3
  • 61
    • 0037085785 scopus 로고    scopus 로고
    • Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: Results of a phase 2 study
    • M. Talpaz, R.T. Silver, B.J. Druker Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia Results of a phase 2 study Blood 99 2002 1928 1937
    • (2002) Blood , vol.99 , pp. 1928-1937
    • Talpaz, M.1    Silver, R.T.2    Druker, B.J.3
  • 62
    • 0033555709 scopus 로고    scopus 로고
    • Identification of DERMO-1 as a member of helix-loop-helix type transcription factors expressed in osteoblastic cells
    • M. Tamura, M. Noda Identification of DERMO-1 as a member of helix-loop-helix type transcription factors expressed in osteoblastic cells J Cell Biochem 72 1999 167 176
    • (1999) J Cell Biochem , vol.72 , pp. 167-176
    • Tamura, M.1    Noda, M.2
  • 63
    • 0038528151 scopus 로고    scopus 로고
    • Aberrant methylation and impaired expression of the p15(INK4b) cell cycle regulatory gene in chronic myelomonocytic leukemia (CMML)
    • M. Tessema, F. Langer, J. Dingemann Aberrant methylation and impaired expression of the p15(INK4b) cell cycle regulatory gene in chronic myelomonocytic leukemia (CMML) Leukemia 17 2003 910 918
    • (2003) Leukemia , vol.17 , pp. 910-918
    • Tessema, M.1    Langer, F.2    Dingemann, J.3
  • 64
    • 0032740836 scopus 로고    scopus 로고
    • Chronic myeloid leukemia from basics to bedside
    • S. Thijsen, G. Schuurhuis, J. van Oostveen Chronic myeloid leukemia from basics to bedside Leukemia 13 1999 1646 1674
    • (1999) Leukemia , vol.13 , pp. 1646-1674
    • Thijsen, S.1    Schuurhuis, G.2    Van Oostveen, J.3
  • 65
    • 0026786945 scopus 로고
    • Genomic hypomethylation in human chronic lymphocytic leukemia
    • J. Wahlfors, H. Hiltunen, K. Heinonen Genomic hypomethylation in human chronic lymphocytic leukemia Blood 80 1992 2074 2080
    • (1992) Blood , vol.80 , pp. 2074-2080
    • Wahlfors, J.1    Hiltunen, H.2    Heinonen, K.3
  • 66
    • 20144366960 scopus 로고    scopus 로고
    • Global assessment of promoter methylation in a mouse model of cancer identifies ID4 as a putative tumor-suppressor gene in human leukemia
    • L. Yu, C. Liu, J. Vandeusen Global assessment of promoter methylation in a mouse model of cancer identifies ID4 as a putative tumor-suppressor gene in human leukemia Nat Genet 37 2005 265 274
    • (2005) Nat Genet , vol.37 , pp. 265-274
    • Yu, L.1    Liu, C.2    Vandeusen, J.3
  • 67
    • 0035100284 scopus 로고    scopus 로고
    • TCL1 is activated by chromosomal rearrangement or by hypomethylation
    • M.R. Yuille, A. Condie, E.M. Stone TCL1 is activated by chromosomal rearrangement or by hypomethylation Genes Chromosomes Cancer 30 2001 336 341
    • (2001) Genes Chromosomes Cancer , vol.30 , pp. 336-341
    • Yuille, M.R.1    Condie, A.2    Stone, E.M.3


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