-
1
-
-
0034707105
-
Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis
-
Bombardier C, Laine L, Reicin A, Shapiro D, Burgos-Vargas R, Davis B, Day R, Ferraz MB, Hawkey CJ, Hochberg MC, Kvein TK, Schnitzer TJ, for the VIGOR Study Group (2000) Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. N Engl J Med 343: 1520-1528
-
(2000)
N Engl J Med
, vol.343
, pp. 1520-1528
-
-
Bombardier, C.1
Laine, L.2
Reicin, A.3
Shapiro, D.4
Burgos-Vargas, R.5
Davis, B.6
Day, R.7
Ferraz, M.B.8
Hawkey, C.J.9
Hochberg, M.C.10
Kvein, T.K.11
Schnitzer, T.J.12
-
2
-
-
0842329914
-
Sulindac targets nuclear β-catenin accumulation and Wnt signalling in adenomas of patients with familial adenomatous polyposis and in human colorectal cancer cell lines
-
Boon EMJ, Keller JJ, Wormhoudt TAM, Giardiello FM, Offerhaus GJA, van der Neut R, Pals ST (2004) Sulindac targets nuclear β-catenin accumulation and Wnt signalling in adenomas of patients with familial adenomatous polyposis and in human colorectal cancer cell lines. Br J Cancer 90: 224-229
-
(2004)
Br J Cancer
, vol.90
, pp. 224-229
-
-
Boon, E.M.J.1
Keller, J.J.2
Wormhoudt, T.A.M.3
Giardiello, F.M.4
Offerhaus, G.J.A.5
Van Der Neut, R.6
Pals, S.T.7
-
3
-
-
0032754225
-
Butyrate-induced apoptotic cascade in colonic carcinoma cells: Modulation of the β-catenin-Tcf pathway and concordance with effects of sulindac and trichostatin A but not curcumin
-
Bordonaro M, Mariadason JM, Aslam F, Heerdt BG, Augenlicht LH (1999) Butyrate-induced apoptotic cascade in colonic carcinoma cells: modulation of the β-catenin-Tcf pathway and concordance with effects of sulindac and trichostatin A but not curcumin. Cell Growth Diff 10: 713-720
-
(1999)
Cell Growth Diff
, vol.10
, pp. 713-720
-
-
Bordonaro, M.1
Mariadason, J.M.2
Aslam, F.3
Heerdt, B.G.4
Augenlicht, L.H.5
-
4
-
-
0034755368
-
Inhibition of β-catenin translocation in rodent colorectal tumors. A novel explanation for the protective effect of nonsteroidal antiinflammatory drugs in colorectal cancer
-
Brown WA, Skinner SA, Vogiagis D, O'Brien PE (2001a) Inhibition of β-catenin translocation in rodent colorectal tumors. A novel explanation for the protective effect of nonsteroidal antiinflammatory drugs in colorectal cancer. Dig Dis Sci 46: 2314-2321
-
(2001)
Dig Dis Sci
, vol.46
, pp. 2314-2321
-
-
Brown, W.A.1
Skinner, S.A.2
Vogiagis, D.3
O'Brien, P.E.4
-
5
-
-
0035033709
-
Non-steroidal anti-inflammatory drugs with activity against either cyclooxygenase-1 or cyclooxygenase-2 inhibit colorectal cancer in a DMH rodent model by inducing apoptosis and inhibiting cell proliferation
-
Brown WA, Skinner SA, Malcontenti-Wilson C, Vogiagis D, O'Brien PE (2001b) Non-steroidal anti-inflammatory drugs with activity against either cyclooxygenase-1 or cyclooxygenase-2 inhibit colorectal cancer in a DMH rodent model by inducing apoptosis and inhibiting cell proliferation. Gut 48: 660-666
-
(2001)
Gut
, vol.48
, pp. 660-666
-
-
Brown, W.A.1
Skinner, S.A.2
Malcontenti-Wilson, C.3
Vogiagis, D.4
O'Brien, P.E.5
-
6
-
-
0033889233
-
Localisation of cyclooxygenase-2 in human sporadic colorectal adenomas
-
Chapple KS, Cartwright EJ, Hawcroft G, Tisbury A, Bonifer C, Scott N, Windsor ACJ, Guillou PJ, Markham AF, Coletta PL, Hull MA (2000) Localisation of cyclooxygenase-2 in human sporadic colorectal adenomas. Am J Pathol 156: 545-553
-
(2000)
Am J Pathol
, vol.156
, pp. 545-553
-
-
Chapple, K.S.1
Cartwright, E.J.2
Hawcroft, G.3
Tisbury, A.4
Bonifer, C.5
Scott, N.6
Windsor, A.C.J.7
Guillou, P.J.8
Markham, A.F.9
Coletta, P.L.10
Hull, M.A.11
-
7
-
-
0035252741
-
The nonsteroidal anti-inflammatory drugs aspirin and indomethacin attenuate β-catenin/TCF-4 signaling
-
Dihlmann S, Siermann A, von Knebel Doeberitz M (2001) The nonsteroidal anti-inflammatory drugs aspirin and indomethacin attenuate β-catenin/TCF-4 signaling. Oncogene 20: 645-653
-
(2001)
Oncogene
, vol.20
, pp. 645-653
-
-
Dihlmann, S.1
Siermann, A.2
Von Knebel Doeberitz, M.3
-
8
-
-
1542649391
-
Reduction of β-catenin/T-cell transcription factor signaling by aspirin and indomethacin is caused by an increased stabilization of phosphorylated β-catenin
-
Dihlmann S, Klein S, von Knebel Doeberitz M (2003) Reduction of β-catenin/T-cell transcription factor signaling by aspirin and indomethacin is caused by an increased stabilization of phosphorylated β-catenin. Mol Cancer Therap 2: 509-516
-
(2003)
Mol Cancer Therap
, vol.2
, pp. 509-516
-
-
Dihlmann, S.1
Klein, S.2
Von Knebel Doeberitz, M.3
-
9
-
-
0036199569
-
Indomethacin induces differential expression of β-catenin, γ-catenin and T-cell factor genes in human colorectal cancer cells
-
Hawcroft G, D'Amico M, Albanese C, Markham AF, Pestell RG, Hull MA (2002) Indomethacin induces differential expression of β-catenin, γ-catenin and T-cell factor genes in human colorectal cancer cells. Carcinogenesis 23: 101-108
-
(2002)
Carcinogenesis
, vol.23
, pp. 101-108
-
-
Hawcroft, G.1
D'Amico, M.2
Albanese, C.3
Markham, A.F.4
Pestell, R.G.5
Hull, M.A.6
-
10
-
-
0037405882
-
Activation of peroxisome proliferator-activated receptor γ does not explain the antiproliferative activity of the nonsteroidal anti-inflammatory drug indomethacin on human colorectal cancer cells
-
Hawcroft G, Gardner SH, Hull MA (2003) Activation of peroxisome proliferator-activated receptor γ does not explain the antiproliferative activity of the nonsteroidal anti-inflammatory drug indomethacin on human colorectal cancer cells. J Pharmacol Exp Therap 305: 632-637
-
(2003)
J Pharmacol Exp Therap
, vol.305
, pp. 632-637
-
-
Hawcroft, G.1
Gardner, S.H.2
Hull, M.A.3
-
11
-
-
0032976834
-
Intracellular distribution of β-catenin in colorectal adenomas, carcinomas and Peutz-Jeghers polyps
-
Herter P, Kuhnen C, Muller K-M, Wittinghofer A, Muller O (1999) Intracellular distribution of β-catenin in colorectal adenomas, carcinomas and Peutz-Jeghers polyps. J Cancer Res Clin Oncol 125: 297-304
-
(1999)
J Cancer Res Clin Oncol
, vol.125
, pp. 297-304
-
-
Herter, P.1
Kuhnen, C.2
Muller, K.-M.3
Wittinghofer, A.4
Muller, O.5
-
12
-
-
0028335192
-
Anti-proliferative effect of nonsteroidal antiinflammatory drugs against human colon cancer cells
-
Hixson LJ, Alberts DS, Krutzsch M, Einsphar J, Brendel K, Gross PH, Shipp Paranka N, Baier M, Emerson S, Pamukcu R, Burt RW (1994) Anti-proliferative effect of nonsteroidal antiinflammatory drugs against human colon cancer cells. Cancer Epidemiol Biomarkers Prev 3: 433-438
-
(1994)
Cancer Epidemiol Biomarkers Prev
, vol.3
, pp. 433-438
-
-
Hixson, L.J.1
Alberts, D.S.2
Krutzsch, M.3
Einsphar, J.4
Brendel, K.5
Gross, P.H.6
Shipp Paranka, N.7
Baier, M.8
Emerson, S.9
Pamukcu, R.10
Burt, R.W.11
-
13
-
-
0041409648
-
The anti-colorectal cancer activity of the non-steroidal anti-inflammatory drug indomethacin
-
Hull MA, Gardner SH, Hawcroft G (2003) The anti-colorectal cancer activity of the non-steroidal anti-inflammatory drug indomethacin. Cancer Treat Rev 29: 309-320
-
(2003)
Cancer Treat Rev
, vol.29
, pp. 309-320
-
-
Hull, M.A.1
Gardner, S.H.2
Hawcroft, G.3
-
14
-
-
0036124654
-
National Cancer Institute workshop on chemopreventive properties of nonsteroidal anti-inflammatory drugs: Role of COX-dependent and -independent mechanisms
-
Hwang DH, Fung V, Dannenberg AJ (2002) National Cancer Institute workshop on chemopreventive properties of nonsteroidal anti-inflammatory drugs: role of COX-dependent and -independent mechanisms. Neoplasia 4: 91-97
-
(2002)
Neoplasia
, vol.4
, pp. 91-97
-
-
Hwang, D.H.1
Fung, V.2
Dannenberg, A.J.3
-
15
-
-
0037126389
-
Paracrine cyclooxygenase-2-mediated signalling by macrophages promotes tumorigenic progression of intestinal epithelial cells
-
Ko SCW, Chapple KS, Hawcroft G, Coletta PL, Markham AF, Hull MA (2002) Paracrine cyclooxygenase-2-mediated signalling by macrophages promotes tumorigenic progression of intestinal epithelial cells. Oncogene 21: 7175-7186
-
(2002)
Oncogene
, vol.21
, pp. 7175-7186
-
-
Ko, S.C.W.1
Chapple, K.S.2
Hawcroft, G.3
Coletta, P.L.4
Markham, A.F.5
Hull, M.A.6
-
16
-
-
0030975671
-
-/- colon carcinoma
-
-/- colon carcinoma. Science 275: 1784-1787
-
(1997)
Science
, vol.275
, pp. 1784-1787
-
-
Korinek, V.1
Barker, N.2
Morin, P.J.3
Van Wichen, D.4
De Weger, R.5
Kinzler, K.W.6
Vogelstein, B.7
Clevers, H.8
-
17
-
-
0036830654
-
Pro-apoptotic actions of exisulind and CP461 in SW480 colon tumor cells involve β-catenin and cyclin D1 down-regulation
-
Li H, Liu L, David ML, Whitehead CM, Chen M, Fetter JR, Sperl GJ, Pamukcu R, Thompson WJ (2002) Pro-apoptotic actions of exisulind and CP461 in SW480 colon tumor cells involve β-catenin and cyclin D1 down-regulation. Biochem Pharmacol 64: 1325-1336
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 1325-1336
-
-
Li, H.1
Liu, L.2
David, M.L.3
Whitehead, C.M.4
Chen, M.5
Fetter, J.R.6
Sperl, G.J.7
Pamukcu, R.8
Thompson, W.J.9
-
19
-
-
0036893756
-
Nonsteroidal anti-inflammatory drugs, apoptosis, and colorectal adenomas
-
Martin C, Connelly A, Keku TO, Mountcastle SB, Galanko J, Woosley JT, Schliebe B, Lund PK, Sandler RS (2002) Nonsteroidal anti-inflammatory drugs, apoptosis, and colorectal adenomas. Gastroenterology 123: 1770-1777
-
(2002)
Gastroenterology
, vol.123
, pp. 1770-1777
-
-
Martin, C.1
Connelly, A.2
Keku, T.O.3
Mountcastle, S.B.4
Galanko, J.5
Woosley, J.T.6
Schliebe, B.7
Lund, P.K.8
Sandler, R.S.9
-
20
-
-
0033028647
-
Relationship of beta-catenin and Bcl-2 expression to sulindac-induced regression of intestinal tumors in Min mice
-
McEntee MF, Chiu CH, Whelan J (1999) Relationship of beta-catenin and Bcl-2 expression to sulindac-induced regression of intestinal tumors in Min mice. Carcinogenesis 20: 635-640
-
(1999)
Carcinogenesis
, vol.20
, pp. 635-640
-
-
McEntee, M.F.1
Chiu, C.H.2
Whelan, J.3
-
21
-
-
0037201536
-
ΔNβ-cat mutant mice to treatment with tea, sulindac and 2-amino-1-methyl-6-phenylimidazol[4,5- b]pyridine (PhIP)
-
ΔNβ-cat mutant mice to treatment with tea, sulindac and 2-amino-1-methyl-6-phenylimidazol[4,5-b]pyridine (PhIP). Mutation Res 506-507: 121-127
-
(2002)
Mutation Res
, vol.506-507
, pp. 121-127
-
-
Orner, G.A.1
Dashwood, W.-M.2
Blum, C.A.3
Diaz, G.D.4
Li, Q.5
Al-Fageeh, M.6
Tebbutt, N.7
Heath, J.K.8
Ernst, M.9
Dashwood, R.H.10
-
22
-
-
0035866401
-
Δ716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor
-
Δ716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor. Cancer Res 61: 1733-1740
-
(2001)
Cancer Res
, vol.61
, pp. 1733-1740
-
-
Oshima, M.1
Murai, N.2
Kargman, S.3
Arguello, M.4
Luk, P.5
Kwong, E.6
Taketo, M.M.7
Evans, J.F.8
-
23
-
-
0030747817
-
Sulindac sulphone inhibits azoxymethane-induced colon carcinogenesis in rats without reducing prostaglandin levels
-
Piazza GA, Alberts DS, Hixson LJ, Paranka NS, Li H, Finn T, Bogert C, Guillen JM, Brendel K, Gross PH, Sperl G, Ritchie J, Burt RW, Ellsworth L, Ahnen DJ, Pamukcu R (1997a) Sulindac sulphone inhibits azoxymethane-induced colon carcinogenesis in rats without reducing prostaglandin levels. Cancer Res 57: 2909-2915
-
(1997)
Cancer Res
, vol.57
, pp. 2909-2915
-
-
Piazza, G.A.1
Alberts, D.S.2
Hixson, L.J.3
Paranka, N.S.4
Li, H.5
Finn, T.6
Bogert, C.7
Guillen, J.M.8
Brendel, K.9
Gross, P.H.10
Sperl, G.11
Ritchie, J.12
Burt, R.W.13
Ellsworth, L.14
Ahnen, D.J.15
Pamukcu, R.16
-
24
-
-
0030968757
-
Apoptosis primarily accounts for the growth-inhibitory properties of sulindac metabolites and involves a mechanism that is independent of cyclooxygenase inhibition, cell cycle arrest and p53 induction
-
Piazza GA, Rahm AK, Finn TS, Li H, Stoumen AL, Pamukcu R, Ahnen DJ (1997b) Apoptosis primarily accounts for the growth-inhibitory properties of sulindac metabolites and involves a mechanism that is independent of cyclooxygenase inhibition, cell cycle arrest and p53 induction. Cancer Res 57: 2452-2459
-
(1997)
Cancer Res
, vol.57
, pp. 2452-2459
-
-
Piazza, G.A.1
Rahm, A.K.2
Finn, T.S.3
Li, H.4
Stoumen, A.L.5
Pamukcu, R.6
Ahnen, D.J.7
-
25
-
-
0030938529
-
Sulindac sulfide inhibits the proliferation of colon cancer cells: Diminished expression of the proliferation markers PCNA and Ki-67
-
Qiao L, Shiff SJ, Rigas B (1997) Sulindac sulfide inhibits the proliferation of colon cancer cells: diminished expression of the proliferation markers PCNA and Ki-67. Cancer Lett 115: 229-234
-
(1997)
Cancer Lett
, vol.115
, pp. 229-234
-
-
Qiao, L.1
Shiff, S.J.2
Rigas, B.3
-
26
-
-
0642287832
-
Sulindac metabolites induce caspase- and proteasome-dependent degradation of β-catenin protein in human colon cancer cells
-
Rice PL, Kelloff J, Sullivan H, Daggers LJ, Beard KS, Kuwada S, Piazza G, Ahnen DJ (2003) Sulindac metabolites induce caspase- and proteasome-dependent degradation of β-catenin protein in human colon cancer cells. Mol Cancer Therap 2: 885-892
-
(2003)
Mol Cancer Therap
, vol.2
, pp. 885-892
-
-
Rice, P.L.1
Kelloff, J.2
Sullivan, H.3
Daggers, L.J.4
Beard, K.S.5
Kuwada, S.6
Piazza, G.7
Ahnen, D.J.8
-
27
-
-
0030038519
-
Nonsteroidal antiinflammatory drugs inhibit the proliferation of colon adenocarcinoma cells: Effects on cell cycle and apoptosis
-
Shiff SJ, Koutsos MI, Qiao L, Rigas B (1996) Nonsteroidal antiinflammatory drugs inhibit the proliferation of colon adenocarcinoma cells: effects on cell cycle and apoptosis. Exp Cell Res 222: 179-188
-
(1996)
Exp Cell Res
, vol.222
, pp. 179-188
-
-
Shiff, S.J.1
Koutsos, M.I.2
Qiao, L.3
Rigas, B.4
-
28
-
-
0033545845
-
The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway
-
Shtutman M, Zhurinsky J, Simcha I, Albanese C, D'Amico M, Pestell R, Ben-Ze'ev A (1999) The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway. Proc Natl Acad Sci USA 96: 5522-5527
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 5522-5527
-
-
Shtutman, M.1
Zhurinsky, J.2
Simcha, I.3
Albanese, C.4
D'Amico, M.5
Pestell, R.6
Ben-Ze'ev, A.7
-
29
-
-
0034057928
-
The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: Evidence of different mechanisms of action
-
Smith M-L, Hawcroft G, Hull MA (2000) The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action. Eur J Cancer 36: 664-674
-
(2000)
Eur J Cancer
, vol.36
, pp. 664-674
-
-
Smith, M.-L.1
Hawcroft, G.2
Hull, M.A.3
-
30
-
-
0031984227
-
β-Catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors
-
Takahashi M, Fukuda K, Sugimura T, Wakabayashi K (1998) β-Catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors. Cancer Res 58: 42-46
-
(1998)
Cancer Res
, vol.58
, pp. 42-46
-
-
Takahashi, M.1
Fukuda, K.2
Sugimura, T.3
Wakabayashi, K.4
-
31
-
-
0034234978
-
Exisulind induction of apoptosis involves guanosine 3′, 5′-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation and attenuated β-catenin
-
Thompson WJ, Piazza GA, Li H, Liu L, Fetter J, Zhu B, Sperl G, Ahnen D, Pamukcu R (2000) Exisulind induction of apoptosis involves guanosine 3′, 5′-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation and attenuated β-catenin. Cancer Res 60: 3338-3342
-
(2000)
Cancer Res
, vol.60
, pp. 3338-3342
-
-
Thompson, W.J.1
Piazza, G.A.2
Li, H.3
Liu, L.4
Fetter, J.5
Zhu, B.6
Sperl, G.7
Ahnen, D.8
Pamukcu, R.9
-
32
-
-
0035052916
-
Inhibition of cellular proliferation through IκB kinase-independent and peroxisome proliferator-activated receptor γ-dependent repression of cyclin D1
-
Wang C, Fu M, D'Amico M, Albanese C, Zhou J-N, Brownlee M, Lisanti MP, Chatterjee VKK, Lazar MA, Pestell RG (2001) Inhibition of cellular proliferation through IκB kinase-independent and peroxisome proliferator-activated receptor γ-dependent repression of cyclin D1. Mol Cell Biol 21: 3057-3070
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3057-3070
-
-
Wang, C.1
Fu, M.2
D'Amico, M.3
Albanese, C.4
Zhou, J.-N.5
Brownlee, M.6
Lisanti, M.P.7
Chatterjee, V.K.K.8
Lazar, M.A.9
Pestell, R.G.10
-
33
-
-
0033594911
-
Nonsteroid drug selectivities for cyclooxygenase-1 rather than cyclooxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis
-
Warner TD, Giuliano F, Vojnovic I, Bukasa A, Mitchell JA, Vane JR (1999) Nonsteroid drug selectivities for cyclooxygenase-1 rather than cyclooxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc Natl Acad Sci USA 96: 7563-7568
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7563-7568
-
-
Warner, T.D.1
Giuliano, F.2
Vojnovic, I.3
Bukasa, A.4
Mitchell, J.A.5
Vane, J.R.6
-
34
-
-
0036174452
-
β-Catenin - A linchpin in colorectal carcinogenesis?
-
Wong NACS, Pignatelli M (2002) β-Catenin - a linchpin in colorectal carcinogenesis? Am J Pathol 160: 380-401
-
(2002)
Am J Pathol
, vol.160
, pp. 380-401
-
-
Wong, N.A.C.S.1
Pignatelli, M.2
-
35
-
-
0037032482
-
Selective cyclooxygenase-2 inhibitors show a differential ability to inhibit proliferation and induce apoptosis of colon adenocarcinoma cells
-
Yamazaki R, Kusunoki N, Matsuzaki T, Hashimoto S, Kawai S (2002) Selective cyclooxygenase-2 inhibitors show a differential ability to inhibit proliferation and induce apoptosis of colon adenocarcinoma cells. FEBS Lett 531: 278-284
-
(2002)
FEBS Lett
, vol.531
, pp. 278-284
-
-
Yamazaki, R.1
Kusunoki, N.2
Matsuzaki, T.3
Hashimoto, S.4
Kawai, S.5
|