-
1
-
-
0000019231
-
WNT genes and breast cancer
-
ed. A.M. Bowcock. Humana Press, Totowa, NJ
-
Bergstein, I. and Brown, A.M.C. 1999. WNT genes and breast cancer. In Breast cancer: Molecular genetics, pathogenesis, and therapeutics (ed. A.M. Bowcock), pp. 181-198. Humana Press, Totowa, NJ.
-
(1999)
Breast Cancer: Molecular Genetics, Pathogenesis, and Therapeutics
, pp. 181-198
-
-
Bergstein, I.1
Brown, A.M.C.2
-
2
-
-
0034644526
-
Linking colorectal cancer to Wnt signaling
-
Bienz, M. and Clevers, H. 2000. Linking colorectal cancer to Wnt signaling. Cell 103: 311-320.
-
(2000)
Cell
, vol.103
, pp. 311-320
-
-
Bienz, M.1
Clevers, H.2
-
3
-
-
0032701521
-
Disruption of p53 in human cancer cells alters the responses to therapeutic agents
-
Bunz, F., Hwang, P.M., Torrance, C., Waldman, T., Zhang, Y., Dillehay, L., Williams, J., Lengauer, C., Kinzler, K.W., and Vogelstein, B. 1999. Disruption of p53 in human cancer cells alters the responses to therapeutic agents. J. Clin. Invest. 104: 263-269.
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 263-269
-
-
Bunz, F.1
Hwang, P.M.2
Torrance, C.3
Waldman, T.4
Zhang, Y.5
Dillehay, L.6
Williams, J.7
Lengauer, C.8
Kinzler, K.W.9
Vogelstein, B.10
-
4
-
-
0031456158
-
Wnt signaling: A common theme in animal development
-
Cadigan, K.M. and Nusse, R. 1997. Wnt signaling: A common theme in animal development. Genes & Dev. 11: 3286-3305.
-
(1997)
Genes & Dev.
, vol.11
, pp. 3286-3305
-
-
Cadigan, K.M.1
Nusse, R.2
-
5
-
-
0025820233
-
Transgenic oncogene mice. Tumor phenotype predicts genotype
-
Cardiff, R.D., Sinn, E., Muller, W., and Leder, P. 1991. Transgenic oncogene mice. Tumor phenotype predicts genotype. Am. J. Pathol. 139: 495-501.
-
(1991)
Am. J. Pathol.
, vol.139
, pp. 495-501
-
-
Cardiff, R.D.1
Sinn, E.2
Muller, W.3
Leder, P.4
-
6
-
-
0033614962
-
Essential role for oncogenic Ras in tumour maintenance
-
Chin, L., Tam, A., Pomerantz, J., Wong, M., Holash, J., Bardeesy, N., Shen, Q., O'Hagan, R., Pantginis, J., Zhou, H., et al. 1999. Essential role for oncogenic Ras in tumour maintenance. Nature 400: 468-472.
-
(1999)
Nature
, vol.400
, pp. 468-472
-
-
Chin, L.1
Tam, A.2
Pomerantz, J.3
Wong, M.4
Holash, J.5
Bardeesy, N.6
Shen, Q.7
O'Hagan, R.8
Pantginis, J.9
Zhou, H.10
-
7
-
-
0035126052
-
c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations
-
D'Cruz, C.M., Gunther, E.J., Boxer, R.B., Hartman, J.L., Sintasath, L., Moody, S.E., Cox, J.D., Ha, S.I., Belka, G.K., Golant, A., et al. 2001. c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations. Nat. Med.7: 235-239.
-
(2001)
Nat. Med.
, vol.7
, pp. 235-239
-
-
D'Cruz, C.M.1
Gunther, E.J.2
Boxer, R.B.3
Hartman, J.L.4
Sintasath, L.5
Moody, S.E.6
Cox, J.D.7
Ha, S.I.8
Belka, G.K.9
Golant, A.10
-
8
-
-
0028951801
-
Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability
-
Donehower, L.A., Godley, L.A., Aldaz, C.M., Pyle, R., Shi, Y.P., Pinkel, D., Gray, J., Bradley, A., Medina, D., and Varmus, H.E. 1995. Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability. Genes & Dev. 9: 882-895.
-
(1995)
Genes & Dev.
, vol.9
, pp. 882-895
-
-
Donehower, L.A.1
Godley, L.A.2
Aldaz, C.M.3
Pyle, R.4
Shi, Y.P.5
Pinkel, D.6
Gray, J.7
Bradley, A.8
Medina, D.9
Varmus, H.E.10
-
9
-
-
0030333191
-
The role of p53 loss in genomic instability and tumor progression in a murine mammary cancer model
-
Donehower, L.A., Godley, L.A., Aldaz, C.M., Pyle, R., Shi, Y.P., Pinkel, D., Gray, J., Bradley, A., Medina, D., and Varmus, H.E. 1996. The role of p53 loss in genomic instability and tumor progression in a murine mammary cancer model. Prog. Clin. Biol. Res. 395: 1-11.
-
(1996)
Prog. Clin. Biol. Res.
, vol.395
, pp. 1-11
-
-
Donehower, L.A.1
Godley, L.A.2
Aldaz, C.M.3
Pyle, R.4
Shi, Y.P.5
Pinkel, D.6
Gray, J.7
Bradley, A.8
Medina, D.9
Varmus, H.E.10
-
10
-
-
0035902115
-
Proliferation, cell cycle, and apoptosis in cancer
-
Evan, G.I. and Vousden, K.H. 2001. Proliferation, cell cycle, and apoptosis in cancer. Nature 411: 342-348.
-
(2001)
Nature
, vol.411
, pp. 342-348
-
-
Evan, G.I.1
Vousden, K.H.2
-
11
-
-
0033180211
-
Reversible tumorigenesis by MYC in hematopoietic lineages
-
Felsher, D.W. and Bishop, J.M. 1999. Reversible tumorigenesis by MYC in hematopoietic lineages. Mol. Cell 4: 199-207.
-
(1999)
Mol. Cell
, vol.4
, pp. 199-207
-
-
Felsher, D.W.1
Bishop, J.M.2
-
12
-
-
0035893318
-
Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes
-
Fisher, G.H., Wellen, S.L., Klimstra, D., Lenczowski, J.M., Tichelaar, J.W., Lizak, M.J., Whitsett, J.A., Koretsky, A., and Varmus, H.E. 2001. Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes. Genes & Dev. 15: 3249-3262.
-
(2001)
Genes & Dev.
, vol.15
, pp. 3249-3262
-
-
Fisher, G.H.1
Wellen, S.L.2
Klimstra, D.3
Lenczowski, J.M.4
Tichelaar, J.W.5
Lizak, M.J.6
Whitsett, J.A.7
Koretsky, A.8
Varmus, H.E.9
-
13
-
-
0033739742
-
Developmental role of the SNF1-related kinase Hunk in pregnancy-induced changes in the mammary gland
-
Gardner, H.P., Belka, G.K., Wertheim, G.B., Hartman, J.L., Ha, S.I., Gimotty, P.A., Marquis, S.T., and Chodosh, L.A. 2000. Developmental role of the SNF1-related kinase Hunk in pregnancy-induced changes in the mammary gland. Development 127: 4493-4509.
-
(2000)
Development
, vol.127
, pp. 4493-4509
-
-
Gardner, H.P.1
Belka, G.K.2
Wertheim, G.B.3
Hartman, J.L.4
Ha, S.I.5
Gimotty, P.A.6
Marquis, S.T.7
Chodosh, L.A.8
-
14
-
-
0036014978
-
Molecular mechanisms of resistance to STI571 in chronic myeloid leukemia
-
Gorre, M.E. and Sawyers, C.L. 2002. Molecular mechanisms of resistance to STI571 in chronic myeloid leukemia. Curr. Opin. Hematol. 9: 303-307.
-
(2002)
Curr. Opin. Hematol.
, vol.9
, pp. 303-307
-
-
Gorre, M.E.1
Sawyers, C.L.2
-
15
-
-
0036187113
-
A novel doxycycline-inducible system for the transgenic analysis of mammary gland biology
-
Gunther, E.J., Belka, G.K., Wertheim, G.B., Wang, J., Hartman, J.L., Boxer, R.B., and Chodosh, L.A. 2002. A novel doxycycline-inducible system for the transgenic analysis of mammary gland biology. FASEB J. 16: 283-292.
-
(2002)
FASEB J.
, vol.16
, pp. 283-292
-
-
Gunther, E.J.1
Belka, G.K.2
Wertheim, G.B.3
Wang, J.4
Hartman, J.L.5
Boxer, R.B.6
Chodosh, L.A.7
-
16
-
-
0032483439
-
Identification of c-MYC as a target of the APC pathway
-
He, T.C., Sparks, A.B., Rago, C., Hermeking, H., Zawel, L., da Costa, L.T., Morin, P.J., Vogelstein, B., and Kinzler, K.W. 1998. Identification of c-MYC as a target of the APC pathway. Science 281: 1509-1512.
-
(1998)
Science
, vol.281
, pp. 1509-1512
-
-
He, T.C.1
Sparks, A.B.2
Rago, C.3
Hermeking, H.4
Zawel, L.5
Da Costa, L.T.6
Morin, P.J.7
Vogelstein, B.8
Kinzler, K.W.9
-
17
-
-
0033987718
-
Reversibility of acute B-cell leukemia induced by BCR-ABL1
-
Huettner, C.S., Zhang, P., Van Etten, R.A., and Tenen, D.G. 2000. Reversibility of acute B-cell leukemia induced by BCR-ABL1. Nat. Genet. 24: 57-60.
-
(2000)
Nat. Genet.
, vol.24
, pp. 57-60
-
-
Huettner, C.S.1
Zhang, P.2
Van Etten, R.A.3
Tenen, D.G.4
-
18
-
-
0035972159
-
Delta N89 β-catenin induces precocious development, differentiation, and neoplasia in mammary gland
-
Imbert, A., Eelkema, R., Jordan, S., Feiner, H., and Cowin, P. 2001. Delta N89 β-catenin induces precocious development, differentiation, and neoplasia in mammary gland. J. Cell Biol. 153: 555-568.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 555-568
-
-
Imbert, A.1
Eelkema, R.2
Jordan, S.3
Feiner, H.4
Cowin, P.5
-
19
-
-
0028118111
-
Tumor spectrum analysis in p53-mutant mice
-
Jacks, T., Remington, L., Williams, B.O., Schmitt, E.M., Halachmi, S., Bronson, R.T., and Weinberg, R.A. 1994. Tumor spectrum analysis in p53-mutant mice. Curr. Biol. 4: 1-7.
-
(1994)
Curr. Biol.
, vol.4
, pp. 1-7
-
-
Jacks, T.1
Remington, L.2
Williams, B.O.3
Schmitt, E.M.4
Halachmi, S.5
Bronson, R.T.6
Weinberg, R.A.7
-
20
-
-
0037025201
-
Sustained loss of a neoplastic phenotype by brief inactivation of MYC
-
Jain, M., Arvanitis, C., Chu, K., Dewey, W., Leonhardt, E., Trinh, M., Sundberg, C.D., Bishop, J.M., and Felsher, D.W. 2002. Sustained loss of a neoplastic phenotype by brief inactivation of MYC. Science 297: 102-104.
-
(2002)
Science
, vol.297
, pp. 102-104
-
-
Jain, M.1
Arvanitis, C.2
Chu, K.3
Dewey, W.4
Leonhardt, E.5
Trinh, M.6
Sundberg, C.D.7
Bishop, J.M.8
Felsher, D.W.9
-
21
-
-
0037169358
-
Apoptosis: A link between cancer genetics and chemotherapy
-
Johnstone, R.W., Ruefli, A.A., and Lowe, S.W. 2002. Apoptosis: A link between cancer genetics and chemotherapy. Cell 108: 153-164.
-
(2002)
Cell
, vol.108
, pp. 153-164
-
-
Johnstone, R.W.1
Ruefli, A.A.2
Lowe, S.W.3
-
22
-
-
0037081290
-
Loss of Wnt-5a protein is associated with early relapse in invasive ductal breast carcinomas
-
Jonsson, M., Dejmek, J., Bendahl, P.-O., and Andersson, T. 2002. Loss of Wnt-5a protein is associated with early relapse in invasive ductal breast carcinomas. Cancer Res. 62: 409-416.
-
(2002)
Cancer Res.
, vol.62
, pp. 409-416
-
-
Jonsson, M.1
Dejmek, J.2
Bendahl, P.-O.3
Andersson, T.4
-
23
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler, K.W. and Vogelstein, B. 1996. Lessons from hereditary colorectal cancer. Cell 87: 159-170.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
24
-
-
0034696336
-
Use of MMTV-Wnt-1 transgenic mice for studying the genetic basis of breast cancer
-
Li, Y., Hively, W.P., and Varmus, H.E. 2000. Use of MMTV-Wnt-1 transgenic mice for studying the genetic basis of breast cancer. Oncogene 19: 1002-1009.
-
(2000)
Oncogene
, vol.19
, pp. 1002-1009
-
-
Li, Y.1
Hively, W.P.2
Varmus, H.E.3
-
25
-
-
0027319521
-
p53 is required for radiation-induced apoptosis in mouse thymocytes
-
Lowe, S.W., Schmitt, E.M., Smith, S.W., Osborne, B.A., and Jacks, T. 1993. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362: 847-849.
-
(1993)
Nature
, vol.362
, pp. 847-849
-
-
Lowe, S.W.1
Schmitt, E.M.2
Smith, S.W.3
Osborne, B.A.4
Jacks, T.5
-
26
-
-
0027944206
-
p53 status and the efficacy of cancer therapy in vivo
-
Lowe, S.W., Bodis, S., McClatchey, A., Remington, L., Ruley, H.E., Fisher, D.E., Housman, D.E., and Jacks, T. 1994. p53 status and the efficacy of cancer therapy in vivo. Science 266: 807-810.
-
(1994)
Science
, vol.266
, pp. 807-810
-
-
Lowe, S.W.1
Bodis, S.2
McClatchey, A.3
Remington, L.4
Ruley, H.E.5
Fisher, D.E.6
Housman, D.E.7
Jacks, T.8
-
27
-
-
0029115660
-
The developmental pattern of Brcal expression implies a role in differentiation of the breast and other tissues
-
Marquis, S.T., Rajan, J.V., Wynshaw-Boris, A., Xu, J., Yin, G.Y., Abel, K.J., Weber, B.L., and Chodosh, L.A. 1995. The developmental pattern of Brcal expression implies a role in differentiation of the breast and other tissues. Nat. Genet. 11: 17-26.
-
(1995)
Nat. Genet.
, vol.11
, pp. 17-26
-
-
Marquis, S.T.1
Rajan, J.V.2
Wynshaw-Boris, A.3
Xu, J.4
Yin, G.Y.5
Abel, K.J.6
Weber, B.L.7
Chodosh, L.A.8
-
28
-
-
0035939818
-
β-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland
-
Michaelson, J.S. and Leder, P. 2001. β-catenin is a downstream effector of Wnt-mediated tumorigenesis in the mammary gland. Oncogene 20: 5093-5099.
-
(2001)
Oncogene
, vol.20
, pp. 5093-5099
-
-
Michaelson, J.S.1
Leder, P.2
-
29
-
-
0037039355
-
Activation of β-catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias
-
Miyoshi, K., Shillingford, J.M., Le Provost, F., Gounari, F., Bronson, R., von Boehmer, H., Taketo, M.M., Cardiff, R.D., Hennighausen, L., and Khazaie, K. 2002. Activation of β-catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias. Proc. Natl. Acad. Sci. 99: 219-224.
-
(2002)
Proc. Natl. Acad. Sci.
, vol.99
, pp. 219-224
-
-
Miyoshi, K.1
Shillingford, J.M.2
Le Provost, F.3
Gounari, F.4
Bronson, R.5
Von Boehmer, H.6
Taketo, M.M.7
Cardiff, R.D.8
Hennighausen, L.9
Khazaie, K.10
-
30
-
-
0027340690
-
ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias
-
Moser, A.R., Mattes, E.M., Dove, W.F., Lindstrom, M.J., Haag, J.D., and Gould, M.N. 1993. ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias. Proc. Natl. Acad. Sci. 90: 8977-8981.
-
(1993)
Proc. Natl. Acad. Sci.
, vol.90
, pp. 8977-8981
-
-
Moser, A.R.1
Mattes, E.M.2
Dove, W.F.3
Lindstrom, M.J.4
Haag, J.D.5
Gould, M.N.6
-
31
-
-
0029312683
-
Histopathology of transgenic mouse mammary tumors (a short atlas)
-
Munn, R.J., Webster, M., Muller, W.J., and Cardiff, R.D. 1995. Histopathology of transgenic mouse mammary tumors (a short atlas). Semin. Cancer Bio. 6: 153-158.
-
(1995)
Semin. Cancer Bio.
, vol.6
, pp. 153-158
-
-
Munn, R.J.1
Webster, M.2
Muller, W.J.3
Cardiff, R.D.4
-
32
-
-
0020216124
-
Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
-
Nusse, R. and Varmus, H.E. 1982. Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome. Cell 31: 99-109.
-
(1982)
Cell
, vol.31
, pp. 99-109
-
-
Nusse, R.1
Varmus, H.E.2
-
33
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis, P. 2000. Wnt signaling and cancer. Genes & Dev. 14: 1837-1851.
-
(2000)
Genes & Dev.
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
34
-
-
0033578918
-
Synergy between tumor suppressor APC and the β-catenin-Tcf4 target Tcf1
-
Roose, J., Huls, G., van Beest, M., Moerer, P., van der Horn, K., Goldschmeding, R., Logtenberg, T., and Clevers, H. 1999. Synergy between tumor suppressor APC and the β-catenin-Tcf4 target Tcf1. Science 285: 1923-1926.
-
(1999)
Science
, vol.285
, pp. 1923-1926
-
-
Roose, J.1
Huls, G.2
Van Beest, M.3
Moerer, P.4
Van der Horn, K.5
Goldschmeding, R.6
Logtenberg, T.7
Clevers, H.8
-
35
-
-
0034123593
-
Mammary gland neoplasia: Insights from transgenic mouse models
-
Siegel, P.M., Hardy, W.R., and Muller, W.J. 2000. Mammary gland neoplasia: Insights from transgenic mouse models. Bioessays 22: 554-563.
-
(2000)
Bioessays
, vol.22
, pp. 554-563
-
-
Siegel, P.M.1
Hardy, W.R.2
Muller, W.J.3
-
36
-
-
0035902140
-
The Hedgehog and Wnt signalling pathways in cancer
-
Taipale, J. and Beachy, P.A. 2001. The Hedgehog and Wnt signalling pathways in cancer. Nature 411: 349-354.
-
(2001)
Nature
, vol.411
, pp. 349-354
-
-
Taipale, J.1
Beachy, P.A.2
-
37
-
-
0024162530
-
Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice
-
Tsukamoto, A.S., Grosschedl, R., Guzman, R.C., Parslow, T., and Varmus, H.E. 1988. Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. Cell 55: 619-625.
-
(1988)
Cell
, vol.55
, pp. 619-625
-
-
Tsukamoto, A.S.1
Grosschedl, R.2
Guzman, R.C.3
Parslow, T.4
Varmus, H.E.5
-
38
-
-
0035855667
-
Wnt pathway and mammary carcinogenesis: Loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type
-
Ugolini, F., Charafe-Jauffret, E., Bardou, V.-J., Geneix, J., Adelaide, J., Labat-Moleur, F., Penault-Llorca, F., Longy, M., Jacquemier, J., Birnbaum, D., et al. 2001. Wnt pathway and mammary carcinogenesis: Loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type. Oncogene 20: 5810-5817.
-
(2001)
Oncogene
, vol.20
, pp. 5810-5817
-
-
Ugolini, F.1
Charafe-Jauffret, E.2
Bardou, V.-J.3
Geneix, J.4
Adelaide, J.5
Labat-Moleur, F.6
Penault-Llorca, F.7
Longy, M.8
Jacquemier, J.9
Birnbaum, D.10
-
39
-
-
0017714532
-
Flow microfluorometric analysis of nuclear DNA in cells from solid tumors and cell suspensions. A new method for rapid isolation and straining of nuclei
-
Vindelov, L.L. 1977. Flow microfluorometric analysis of nuclear DNA in cells from solid tumors and cell suspensions. A new method for rapid isolation and straining of nuclei. Virchows Arch. B Cell Pathol. 24: 227-242.
-
(1977)
Virchows Arch. B Cell Pathol.
, vol.24
, pp. 227-242
-
-
Vindelov, L.L.1
-
40
-
-
0037154738
-
Effect of p53 status on tumor response to antiangiogenic therapy
-
Yu, J.L., Rak, J.W., Coomber, B.L., Hicklin, D.J., and Kerbel, R.S. 2002. Effect of p53 status on tumor response to antiangiogenic therapy. Science 295: 1526-1528.
-
(2002)
Science
, vol.295
, pp. 1526-1528
-
-
Yu, J.L.1
Rak, J.W.2
Coomber, B.L.3
Hicklin, D.J.4
Kerbel, R.S.5
|